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Handbook Of Advanced Chromatography Mass Spectrometry Techniques

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Handbook of Advanced Chromatography mass Spectrometry Techniques

Handbook of Advanced Chromatography mass Spectrometry Techniques Book
Author : Michal Holčapek,William Craig Byrdwell
Publisher : Unknown
Release : 2017
ISBN : 9781523114450
Language : En, Es, Fr & De

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Book Description :

Handbook of Advanced Chromatography /Mass Spectrometry Techniques is a compendium of new and advanced analytical techniques that have been developed in recent years for analysis of all types of molecules in a variety of complex matrices, from foods to fuel to pharmaceuticals and more. Focusing on areas that are becoming widely used or growing rapidly, this is a comprehensive volume that describes both theoretical and practical aspects of advanced methods for analysis. Written by authors who have published the foundational works in the field, the chapters have an emphasis on lipids, but reach a broader audience by including advanced analytical techniques applied to a variety of fields. Handbook of Advanced Chromatography / Mass Spectrometry Techniques is the ideal reference for those just entering the analytical fields covered, but also for those experienced analysts who want a combination of an overview of the techniques plus specific and pragmatic details not often covered in journal reports. The authors provide, in one source, a synthesis of knowledge that is scattered across a multitude of literature articles. The combination of pragmatic hints and tips with theoretical concepts and demonstrated applications provides both breadth and depth to produce a valuable and enduring reference manual. It is well suited for advanced analytical instrumentation students as well as for analysts seeking additional knowledge or a deeper understanding of familiar techniques.

Handbook of Advanced Chromatography Mass Spectrometry Techniques

Handbook of Advanced Chromatography  Mass Spectrometry Techniques Book
Author : Michal Holcapek,Wm. Craig Byrdwell
Publisher : Elsevier
Release : 2017-09-07
ISBN : 0128117338
Language : En, Es, Fr & De

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Book Description :

Handbook of Advanced Chromatography /Mass Spectrometry Techniques is a compendium of new and advanced analytical techniques that have been developed in recent years for analysis of all types of molecules in a variety of complex matrices, from foods to fuel to pharmaceuticals and more. Focusing on areas that are becoming widely used or growing rapidly, this is a comprehensive volume that describes both theoretical and practical aspects of advanced methods for analysis. Written by authors who have published the foundational works in the field, the chapters have an emphasis on lipids, but reach a broader audience by including advanced analytical techniques applied to a variety of fields. Handbook of Advanced Chromatography / Mass Spectrometry Techniques is the ideal reference for those just entering the analytical fields covered, but also for those experienced analysts who want a combination of an overview of the techniques plus specific and pragmatic details not often covered in journal reports. The authors provide, in one source, a synthesis of knowledge that is scattered across a multitude of literature articles. The combination of pragmatic hints and tips with theoretical concepts and demonstrated applications provides both breadth and depth to produce a valuable and enduring reference manual. It is well suited for advanced analytical instrumentation students as well as for analysts seeking additional knowledge or a deeper understanding of familiar techniques. Includes UHPLC, HILIC, nano-liquid chromatographic separations, two-dimensional LC-MS (LCxLC), multiple parallel MS, 2D-GC (GCxGC) methodologies for lipids analysis, and more Contains both practical and theoretical knowledge, providing core understanding for implementing modern chromatographic and mass spectrometric techniques Presents chapters on the most popular and fastest-growing new techniques being implemented in diverse areas of research

Handbook of Bioanalytics

Handbook of Bioanalytics Book
Author : Bogusław Buszewski,Irena Baranowska
Publisher : Springer Nature
Release : 2022-08-01
ISBN : 3030956601
Language : En, Es, Fr & De

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Book Description :

This book presents an authoritative review of analytical methods used for diagnostics, medical therapy and for forensic purposes. Divided into 4 parts, the book discusses new challenges in bioanalytics, covers bioanalysis as a source of clinical, pharmaceutical and forensic information, explores natural resources as a source of biologically active compounds, and offers new analytical strategies and equipment solutions. Written by interdisciplinary expert academics, this work will appeal to a wide readership of students, researchers and professionals interested in the fields of medicine, chemistry, pharmaceutical, life and health sciences, engineering and environmental protection. Clinicians and employees of forensic laboratories will also find this work instructive and informative.

Identification and Quantification of Drugs Metabolites Drug Metabolizing Enzymes and Transporters

Identification and Quantification of Drugs  Metabolites  Drug Metabolizing Enzymes  and Transporters Book
Author : Shuguang Ma,Swapan Chowdhury
Publisher : Elsevier
Release : 2020-07-09
ISBN : 0128200197
Language : En, Es, Fr & De

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Book Description :

Identification and Quantification of Drugs, Metabolites, Drug Metabolizing Enzymes, and Transporters, Second Edition, is completely updated to provide an overview of the last decade’s numerous advances in analytical technologies for detection and quantification of drugs, metabolites, and biomarkers. This new edition goes beyond LC-MS and features all-new chapters on how to evaluate drug absorption, distribution, metabolism, and excretion, potential for hepatic and renal toxicity, immunogenicity of biotherapeutics and translational tools for predicting human dosage, safety and efficacy of small molecules and biologics. This book will be an important handbook and desk reference for pharmacologists, toxicologists, clinical scientists, and students interested in the fields of pharmacology, biochemistry, and drug metabolism. Four sections in the book with 24 chapters give readers an overview of state-of-the-art techniques for identifying and quantifying drugs, metabolites and biomarkers, including a chapter on new approaches for quantification of enzymes and transporters in different tissues Focuses on the role of drug metabolism enzymes, transporters in disposition and drug-drug interactions, as well as strategies for evaluating drug metabolism and safety using advanced liver and kidney models. Discussions on immunogenicity risks of biologics and their evaluation methods have been included Includes several chapters on advanced translational sciences to predict human dosage, pharmacokinetics and efficacy for small molecules and biotherapeutics All chapters are written by experts with a wide range of practical experience from the industry and academia

Supercritical Fluid Chromatography

Supercritical Fluid Chromatography Book
Author : Gérard Rossé
Publisher : Walter de Gruyter GmbH & Co KG
Release : 2018-12-17
ISBN : 3110618982
Language : En, Es, Fr & De

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Book Description :

Supercritical Fluid Chromatography (SFC) provides a timely overview of SFC application areas which were unimaginable just a decade ago. This two-volume series opens with an overview of the history and expectant future of SFC and continues with recent applications in the pharmaceutical industry and other fascinating areas of science. SFC has found its place in the pharmaceutical industry with an increasing body of applications for chiral and achiral molecules in both the research and development phases of the drug discovery process. As illustrated in this two-volume series, the current interest in SFC extends well beyond the pharmaceutical industry. Chapters encompassing applications for polar and non-polar mixtures of importance are covering widely disparate areas in substance abuse, natural products including cannabinoids, bioactive lipids, flavor and fragrance. With its broad balance and coverage, this two-volume book constitutes a unique educational platform to students and scientists for many years to come. The major objective of this book editions is to inspire and stimulate readers to continue exploring the possibilities of exploiting supercritical fluids as a particular media for analysis, purifications and synthesis

Advances in Chromatography

Advances in Chromatography Book
Author : Nelu Grinberg,Peter W. Carr
Publisher : CRC Press
Release : 2019-02-07
ISBN : 0429651961
Language : En, Es, Fr & De

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Book Description :

For more than five decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-todate information on a wide range of developments in chromatographic methods and applications. The clear presentation of topics and vivid illustrations for which this series has become known makes the material accessible and engaging to analytical, biochemical, organic, polymer, and pharmaceutical chemists at all levels of technical skill. Key Features: Includes a chapter dedicated to Izaak Maurits Kolthoff, offering a unique look at his non-professional life as well as his impact and legacy in Analytical Chemistry. Discusses recent advances in two-dimensional liquid chromatography for the characterization of monoclonal antibodies and other therapeutic proteins. Reviews solvation processes, methodologies of their measurement, and parameters influenced solvation Explores recent advances in TLC analysis of natural colorings, determination of synthetic dyes, and determination of EU-permitted natural colors, in foods. Offers comprehensive and critical insights on the key aspects of CE-MS analysis of intact proteins

Forensic Chemistry

Forensic Chemistry Book
Author : Suzanne Bell
Publisher : CRC Press
Release : 2022-04-28
ISBN : 0429804458
Language : En, Es, Fr & De

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Book Description :

Forensic Chemistry, Third Edition, the new edition of this ground-breaking book, continues to serve as the leading forensic chemistry text on the market. Fully updated, this edition describes the latest advances in current forensic chemistry analysis and practice. New and expanded coverage includes rapid advances in forensic mass spectrometry, NMR, and novel psychoactive substances (NPSs). Topics related to seized drug analysis, toxicology, combustion and fire investigation, explosives, and firearms discharge residue are described and illustrated with case studies. The role of statistics, quality assurance/quality control, uncertainty, and metrology are integrated into all topics. More pharmacological and toxicokinetic calculations are presented and discussed. Hundreds of color figures, along with graphs, illustrations, worked example problems, and case descriptions are used to show how analytical chemistry is applied to forensic practice. Topics covered offer students insight into the legal context in which forensic chemistry is conducted and introduces them to the sample types and sample matrices encountered in forensic laboratories.

Separation Techniques Applied to Omics Sciences

Separation Techniques Applied to Omics Sciences Book
Author : Ana Valéria Colnaghi Simionato
Publisher : Springer Nature
Release : 2021-10-09
ISBN : 3030772527
Language : En, Es, Fr & De

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Book Description :

This book covers liquid chromatography, gas chromatography and capillary electrophoresis, the three main separation techniques lately available, applied to key omic sciences, such as genomics, proteomics, metabolomics and foodomics. The fundamentals of each technique are not covered herein. Instead, the recent advances in such techniques are presented focusing on the application to omics analyses and unique aspects in each case. This volume intends to offer wide ranging options available to researchers on omics sciences, and how to integrate them in order to achieve the comprehension of a biological system as a whole. Omic sciences have been of ultimate importance to comprehend the complex biochemical reactions and related events that occurs upon a biological system. The classical central dogma of molecular biology, which states that genetic information flows unidirectionally from DNA to RNA and then to proteins, has been gradually replaced by the systems biology approach. This book presents a multidisciplinary approach that explains the biological system as a whole, where the entire organism is influenced by a variety of internal events as well as by the environment, showing that each level of the biological information flux may influence the previous or the subsequent one.

Advanced Techniques in Gas Chromatography Mass Spectrometry GC MS MS and GC TOF MS for Environmental Chemistry

Advanced Techniques in Gas Chromatography Mass Spectrometry  GC MS MS and GC TOF MS  for Environmental Chemistry Book
Author : Anonim
Publisher : Newnes
Release : 2013-09-26
ISBN : 0444626247
Language : En, Es, Fr & De

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Book Description :

Gas chromatography mass spectrometry (GC-MS) has been the technique of choice of analytical scientists for many years. The latest developments in instrumentation, including tandem mass spectrometry (MS-MS) and time-of-flight (TOF) detectors, have opened up and broadened the scope of environmental analytical chemistry. This book summarizes the major advances and relevant applications of GC-MS techniques over the last 10 years, with chapters by leading authors in the field of environmental chemistry. The authors are drawn from academia, industry and government. The book is organized in three main parts. Part I covers applications of basic GC-MS to solve environmental-related problems. Part II focuses on GC-MS-MS instrumentation for the analyses of a broad range of analysis in environmental samples (pesticides, persistent organic pollutants, endocrine disruptors, etc.). Part III covers the use of more advanced GC-MS techniques using low- and high-resolution mass spectrometry for many applications related to the environment, food and industry. Summarizes the major advances of GC-MS techniques in the last decade Presents relevant applications of GC-MS techniques Covers academic, industrial and governmental sectors

Mass Spectrometry Handbook

Mass Spectrometry Handbook Book
Author : Mike S. Lee
Publisher : John Wiley & Sons
Release : 2012-04-16
ISBN : 1118180720
Language : En, Es, Fr & De

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Book Description :

Due to its enormous sensitivity and ease of use, mass spectrometry has grown into the analytical tool of choice in most industries and areas of research. This unique reference provides an extensive library of methods used in mass spectrometry, covering applications of mass spectrometry in fields as diverse as drug discovery, environmental science, forensic science, clinical analysis, polymers, oil composition, doping, cellular research, semiconductor, ceramics, metals and alloys, and homeland security. The book provides the reader with a protocol for the technique described (including sampling methods) and explains why to use a particular method and not others. Essential for MS specialists working in industrial, environmental, and clinical fields.

Liquid Chromatography Mass Spectrometry

Liquid Chromatography   Mass Spectrometry Book
Author : Robert E. Ardrey
Publisher : John Wiley & Sons
Release : 2003-07-25
ISBN : 0470862173
Language : En, Es, Fr & De

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Book Description :

First explaining the basic principles of liquid chromatography and mass spectrometry and then discussing the current applications and practical benefits of LC-MS, along with descriptions of the basic instrumentation, this title will prove to be the indispensable reference source for everyone wishing to use this increasingly important tandem technique. * First book to concentrate on principles of LC-MS * Explains principles of mass spectrometry and chromatography before moving on to LC-MS * Describes instrumental aspects of LC-MS * Discusses current applications of LC-MS and shows benefits of using this technique in practice

Tools and Trends in Bioanalytical Chemistry

Tools and Trends in Bioanalytical Chemistry Book
Author : Lauro Tatsuo Kubota,José Alberto Fracassi da Silva,Marcelo Martins Sena,Wendel Andrade Alves
Publisher : Springer Nature
Release : 2021-11-25
ISBN : 3030823814
Language : En, Es, Fr & De

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Book Description :

This textbook covers the main tools and techniques used in bioanalysis, provides an overview of their principles, and offers several examples of their application and future trends in diagnosis. Chapters from expert contributors explore the role of bioanalysis in different areas such as biochemistry, physiology, forensics, and clinical diagnosis, including topics from sampling/sample preparation, chemometrics in bioanalysis to the latest techniques used in the field. Particular attention is given to the recent advances in the application of mass spectrometry, NMR, electrochemical methods and separation techniques in bioanalysis. Readers will also find more about the application of microchip-based devices and analytical microarrays. This textbook will appeal to graduate/advanced undergraduate students in Chemistry, Biology, Biochemistry, Pharmacy, and Chemical Engineering. It is also a useful resource for researchers and professionals working in the fields of biomedicine and veterinary sciences, with clear explanations and examples of how the different bioanalytical devices are applied for clinical diagnosis.

Gas Chromatography Mass Spectrometry

Gas Chromatography   Mass Spectrometry Book
Author : Diane C Turner,Mathias Schäfer,Steven Lancaster,Imran Janmohamed,Anthony Gachanja,Jason Creasey
Publisher : Royal Society of Chemistry
Release : 2019-11-28
ISBN : 1782629289
Language : En, Es, Fr & De

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Book Description :

Gas chromatography–mass spectrometry (GC-MS) is a powerful way to analyse a range of substances. It is used in everything from food safety to medicine. It has even been used to protect endangered vultures through analysis of poisonous pesticide molecules in their environment! I want to apply this technique, where do I begin? Is GC-MS is the right technique to use? How do I prepare my samples and calibrate the instruments? This textbook has the answers to all these questions and more. Throughout the book, case studies illustrate the practical process, the techniques used and any common challenges. Newcomers can easily search for answers to their question and find clear advice with coloured images on how to get started and all subsequent steps involved in using GC-MS as part of a research process. Readers will find information on collecting and preparing samples, designing and validating methods, analysing results, and troubleshooting. Examples of pollutant, food, oil and fragrance analysis bring the theory to life. The authors use their extensive experience teaching GC-MS theory and practice and draw on their combined backgrounds applying the technique in academic and industry settings to bring this practical reference together. The authors also design and teach the Royal Society of Chemistry’s Pan Africa Chemistry Network GC-MS course, which is supported by GSK.

Nanotechnology in the Beverage Industry

Nanotechnology in the Beverage Industry Book
Author : Abdeltif Amrane,Susai Rajendran,Tuan Anh Nguyen,Ashraf Mahdy Sharoba,Aymen Amine Assadi
Publisher : Elsevier
Release : 2020-05-04
ISBN : 0128199415
Language : En, Es, Fr & De

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Book Description :

Nanotechnology in the Beverage industry: Fundamentals and Applications looks at how nanotechnology is being used to enhance water quality, as well as how the properties of nanomaterials can be used to create different properties in both alcoholic and no-alcoholic drinks and enhance the biosafety of both drinks and their packaging. This is an important reference for materials scientists, engineers, food scientists and microbiologists who want to learn more about how nanotechnology is being used to enhance beverage products. As active packaging technology, nanotechnology can increase shelf-life and maintain the quality of beverages. In the field of water treatment, nanomaterials offer new routes to address challenges.

Amino Acids Peptides and Proteins Volume 44

Amino Acids  Peptides and Proteins Volume 44 Book
Author : Maxim Ryadnov,Ferenc Hudecz
Publisher : Royal Society of Chemistry
Release : 2020-12-08
ISBN : 1788016890
Language : En, Es, Fr & De

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Book Description :

Compiled by leading researchers, Amino Acids, Peptides and Proteins is a broad ranging title comprising comprehensive and critical reviews of significant developments at the biology and chemistry interface.

Handbook of GC MS

Handbook of GC MS Book
Author : Hans-Joachim Hübschmann
Publisher : John Wiley & Sons
Release : 2015-07-27
ISBN : 3527334742
Language : En, Es, Fr & De

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Book Description :

The only comprehensive reference on this popular and rapidly developing technique provides a detailed overview, ranging from fundamentals to applications, including a section on the evaluation of GC-MS analyses. As such, it covers all aspects, including the theory and principles, as well as a broad range of real-life examples taken from laboratories in environmental, food, pharmaceutical and clinical analysis. It also features a glossary of approximately 300 terms and a substance index that facilitates finding a specific application. For this new edition the work has been now extended to two volumes, reflecting the latest developments in the technique and related instrumentation, while also incorporating several new examples of applications in many fields. The first two editions were very well received, making this handbook a must-have in all analytical laboratories using GC-MS.

Handbook of Food Analysis Two Volume Set

Handbook of Food Analysis   Two Volume Set Book
Author : Leo M.L. Nollet,Fidel Toldra
Publisher : CRC Press
Release : 2015-06-10
ISBN : 1482297841
Language : En, Es, Fr & De

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Book Description :

Updated to reflect changes in the industry during the last ten years, The Handbook of Food Analysis, Third Edition covers the new analysis systems, optimization of existing techniques, and automation and miniaturization methods. Under the editorial guidance of food science pioneer Leo M.L. Nollet and new editor Fidel Toldra, the chapters take an in

Pharmaceutical Analysis E Book

Pharmaceutical Analysis E Book Book
Author : David G. Watson
Publisher : Elsevier Health Sciences
Release : 2020-06-10
ISBN : 0702078093
Language : En, Es, Fr & De

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Book Description :

Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of analyses, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals. The mathematics involved is notoriously difficult, but this much-praised and well established textbook, now revised and updated for its fifth edition, guides a student through the complexities with clear writing and the author's expertise from many years' teaching pharmacy students. Worked calculation examples and self-assessment test questions aid continuous learning reinforcement throughout Frequent use of figures and diagrams clarify points made in the text Practical examples are used to show the application of techniques Key points boxes summarise the need to know information for each topic Focuses on the most relevant and frequently used techniques within the field

Handbook of Essential Oils

Handbook of Essential Oils Book
Author : K. Husnu Can Baser,Gerhard Buchbauer
Publisher : CRC Press
Release : 2020-08-11
ISBN : 1351246445
Language : En, Es, Fr & De

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Book Description :

Handbook of Essential Oils: Science, Technology, and Applications presents the development, use and marketing of essential oils. Exciting new topics include insecticidal applications, but there is a continued focus on the chemistry, pharmacology and biological activities of essential oils. The third edition unveils new chapters including the insect repellent and insecticidal activities of essential oils, the synergistic activity with antibiotics against resistant microorganisms, essential oil applications in agriculture, plant-insect interactions, and pheromones and contaminants in essential oils. Features Presents a wide range of topics including sources, production, analysis, storage, transport, chemistry, aromatherapy, pharmacology, toxicology, metabolism, technology, biotransformation, application, utilization, and trade Includes discussions of biological activity testing, results of antimicrobial and antioxidant tests, and penetration enhancing activities useful in drug delivery Covers up-to-date regulations and legislative procedures, together with the use of essential oils in perfumes, cosmetics, feed, food, beverages, and pharmaceutical industries Unveils new chapters including the insect repellent and insecticidal activities of essential oils, the synergistic activity with antibiotics against resistant microorganisms, essential oil applications in agriculture, plant-insect interactions, and pheromones and contaminants in essential oils The American Botanical Council (ABC) named the second edition as the recipient of the 2016 ABC James A. Duke Excellence in Botanical Literature Award and recognized that essential oils are one of the fastest growing segments of the herbal product market

Handbook of Modern Sensors

Handbook of Modern Sensors Book
Author : Jacob Fraden
Publisher : Springer Science & Business Media
Release : 2004
ISBN : 0387007504
Language : En, Es, Fr & De

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Book Description :

This book is about devices commonly called sensors. Digital systems, however complex and intelligent they might be, must receive information from the outside world that is generally analog and not electrical. Sensors are interface devices between various physical values and the electronic circuits who "understand" only a language of moving electrical charges. In other words, sensors are the eyes, ears, and noses of silicon chips. Unlike other books on sensors, this book is organized according to the measured variables (temperature, pressure, position, etc.) that make it much more practical and easier to read. In this new edition recent ideas and developments have been added while less important and non-essential designs were dropped. Sections on practical designs and use of the modern micro-machining technologies have been revised substantially. This book is a reference text that can be used by students, researchers interested in modern instrumentation (applied physicists and engineers), sensor designers, application engineers and technicians whose job it is to understand, select and/or design sensors for practical systems. The scope of this book is rather broad covering many different designs. Some are well known, but describing them is still useful for students and those who look for a convenient reference. It is the author's intention to present a comprehensive and up-to-date account of the theory (physical principles), design, and practical implementations of various sensors for scientific, industrial, and consumer applications.nbsp;nbsp;From the reviews:"... A very useful book ... It strikes an excellent balance between a large variety of different sensor types and moderate description of each to yield a book of reasonable length ... Provides excellent information on all types of physical measurements. I recommend it highly." Biomedical Instrumentation & Technology"Jacob Fraden has produced a valuable, single-volume reference on the devices that bridge the analog and digital worlds." Lawrence Rubin, MIT From the reviews of the third edition:"This is a weighty volume of nearly 600 pages. ... The book is undoubtedly useful as a source of reference. The large number of sensors described in it, and the consideration of underlying principles of operation should help people ... ." (Allan Hobson, Robotica, Vol. 23, 2005)"This book handles the basic and absolutely most important common areas of all sensor applications. It gives a good overview of a very wide range of sensor applications, which is not found in many other books in such a detailed form. ... This book is useful for everybody who works with any kind of measurement technique. For beginners it is a good introduction to the world of sensors. For advanced users it is a good and extensive handbook and help." (Rüdiger Frank, Analytical and Bioanalytical Chemistry, Vol. 382, 2005)"This book ... aims for breadth and to be a reasonably comprehensive account of most modern sensors. ... The Handbook is a readable reference text for researchers, graduate students and engineers ... . Don't read this book if you don't want to know how the sensors work ... . If, however you want to understand how a sensor works, the principle behind it ... or use all that sensors have to offer technically, then this book is for you." (Stephen Kukureka Fimmm, Materials World, Vol. 13 (2), February, 2005)