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Gut Microbiota In Neurologic And Visceral Diseases

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Gut Microbiota in Neurologic and Visceral Diseases

Gut Microbiota in Neurologic and Visceral Diseases Book
Author : Tahira Farooqui,Akhlaq A. Farooqui
Publisher : Academic Press
Release : 2021-03-24
ISBN : 0128210400
Language : En, Es, Fr & De

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Book Description :

Gut Microbiota in Neurologic and Visceral Diseases presents readers with comprehensive information on the involvement of microbiota in the pathogenesis of neurological disorders. Chapters cover the effect of microbiota on the development of visceral (obesity, type 2 diabetes, heart disease) and neurological disorders (Alzheimer’s disease, Parkinson’s, depression, anxiety, and autism). Sections focus on the molecular mechanisms and signal transduction processes associated with the links among microbiota-related visceral and neurological disorders. It is hoped that this discussion will not only integrate and consolidate knowledge in this field but will also jumpstart more studies on the involvement of microbiota in the pathogenesis of neurological disorders. Reviews the relationship between gut microbiome, diseases and disorders Discusses the relationship between diet, microbiota and inflammation Includes neurodegenerative, neuropsychiatric and cardiovascular disorders Covers diabetes, obesity and metabolic disorders Identifies molecular mechanisms and signal transduction processes Encompasses dietary fiber, fat, prebiotics and probiotics

Insulin Resistance As a Risk Factor in Visceral and Neurological Disorders

Insulin Resistance As a Risk Factor in Visceral and Neurological Disorders Book
Author : Akhlaq A. Farooqui
Publisher : Academic Press
Release : 2020-03
ISBN : 0128196033
Language : En, Es, Fr & De

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Book Description :

Insulin Resistance as a Risk Factor in Visceral and Neurological Disorders provides an overview on the risk factors for insulin resistance in visceral and neurological disorders. The book focuses on molecular mechanisms and signal transduction processes associated with the links. The comprehensive information in this monograph will not only help in the early detection of insulin resistance related visceral and neurological disorders, but also promote the discovery of new drugs which may block or delay onset in elderly patients. Understanding these processes is important not only for patients, caregivers and health professionals, but also for health policymakers who must plan for national resources.

Neuroinflammation Resolution and Neuroprotection in the Brain

Neuroinflammation  Resolution  and Neuroprotection in the Brain Book
Author : Akhlaq A. Farooqui
Publisher : Academic Press
Release : 2021-10-01
ISBN : 032388461X
Language : En, Es, Fr & De

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Book Description :

Neuroinflammation, Resolution, and Neuroprotection in the Brain discusses the molecular aspects of neuroinflammation in neurological disorders. The book examines the effect of diet and exercise on neuroinflammatory diseases. Chapters focus on bioactive lipids, cytokines and chemokines, as well as the involvement of neuroinflammation, resolution and neuroprotection in neurotraumatic diseases, neurodegenerative diseases and neuropsychiatric diseases. The comprehensive information in this monograph will help readers understand molecular cross-talk among mediators of phospholipid, sphingolipid and cholesterol metabolism. The book's goal is to jumpstart more studies on molecular mechanisms and the therapeutic aspects of neurological disorders in human subjects. Discusses the molecular aspects of neuroinflammation, resolution and neuroprotection Examines the role of diet and exercise on neuroinflammatory diseases Provides cutting-edge research on signal transduction processes Explores the treatment of neurological disorders caused by neuroinflammation

Neuro Immuno Gastroenterology

Neuro Immuno Gastroenterology Book
Author : Cris S. Constantinescu,Rāzvan I. Arsenescu,Violeta Arsenescu
Publisher : Springer
Release : 2016-05-24
ISBN : 3319286099
Language : En, Es, Fr & De

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Book Description :

This book addresses important issues regarding the interaction between the nervous system, the immune system, and the digestive system. Gut flora has a profound influence on the shaping of the immune response, not only in the gastrointestinal system but also in the nervous system. Fascinatingly, manipulation of intestinal immune responses can be used to modulate neurological disease. Conversely, the nervous system and the psyche have significant effects on the functioning of the gut and liver. After introductory chapters on the neurology, the immunology and microbiology of the gut, the effects of the gut immune system and gut flora and its manipulation on neurological disease are discussed, followed by molecular mimicry and immune tolerance in neuroimmune diseases. Additionally, several chapters deal with gastrointestinal manifestations of neurological diseases. Neuro-Immuno-Gastroenterology is aimed at neurologists, gastroenterologists, and immunologists.

Microbial Endocrinology The Microbiota Gut Brain Axis in Health and Disease

Microbial Endocrinology  The Microbiota Gut Brain Axis in Health and Disease Book
Author : Mark Lyte,John F. Cryan
Publisher : Springer
Release : 2014-07-05
ISBN : 1493908979
Language : En, Es, Fr & De

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Book Description :

The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host (“us”). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease.​

Molecular Aspects of Neurodegeneration Neuroprotection and Regeneration in Neurological Disorders

Molecular Aspects of Neurodegeneration  Neuroprotection  and Regeneration in Neurological Disorders Book
Author : Akhlaq A. Farooqui
Publisher : Academic Press
Release : 2020-09-07
ISBN : 0128217014
Language : En, Es, Fr & De

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Book Description :

Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of neurological disorders. The book covers information on signal transduction processes associated with neurochemistry of neurological disorders, including neurodegenerative, neurotraumatic, and neuropsychiatric disorders. The book also discusses risk factors, symptoms, pathogenesis, biomarkers, and the potential treatments of neurological disorders. The comprehensive information in this monograph may not only help in early detection of various neurological disorders, but will also promote the discovery of new drugs. Provides a comprehensive overview of the molecular aspects of neurodegeneration, neuroprotection, and neuro-regeneration, along with therapeutic strategies for various types of neurological disorders Provides cutting-edge research information on the signal transduction processes associated with the neurochemistry of neurological disorders Discusses risk factors, symptoms, pathogenesis, biomarkers, and the potential for treatments of neurological disorders

Handbook of Developmental Neurotoxicology

Handbook of Developmental Neurotoxicology Book
Author : William Slikker, Jr.,Merle G. Paule,Cheng Wang
Publisher : Academic Press
Release : 2018-01-04
ISBN : 0128093943
Language : En, Es, Fr & De

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Book Description :

Handbook of Developmental Neurotoxicology, Second Edition, provides a comprehensive view of the fundamental aspects of neurodevelopment, the pathways and agents that affect them, relevant clinical syndromes, and risk assessment procedures for developmental neurotoxicants. The editors and chapter authors are internationally recognized experts whose collaboration heralds a remarkable advance in the field, bridging developmental neuroscience with the principles of neurotoxicology. The book features eight new chapters with newly recruited authors, making it an essential text for students and professionals in toxicology, neurotoxicology, developmental biology, pharmacology, and neuroscience. Presents a comprehensive, up-to-date resource on developmental neurotoxicology with updated chapters from the first edition Contains new chapters that focus on subjects recent to the field Includes well-illustrated material, with diagrams, charts, and tables Contains compelling case studies and chapters written by world experts

Metabonomics and Gut Microbiota in Nutrition and Disease

Metabonomics and Gut Microbiota in Nutrition and Disease Book
Author : Sunil Kochhar,François-Pierre Martin
Publisher : Springer
Release : 2014-10-21
ISBN : 144716539X
Language : En, Es, Fr & De

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Book Description :

This book provides a comprehensive overview of metabonomics and gut microbiota research from molecular analysis to population-based global health considerations. The topics include the discussion of the applications in relation to metabonomics and gut microbiota in nutritional research, in health and disease and a review of future therapeutical, nutraceutical and clinical applications. It also examines the translatability of systems biology approaches into applied clinical research and to patient health and nutrition. The rise in multifactorial disorders, the lack of understanding of the molecular processes at play and the needs for disease prediction in asymptomatic conditions are some of the many questions that system biology approaches are well suited to address. Achieving this goal lies in our ability to model and understand the complex web of interactions between genetics, metabolism, environmental factors and gut microbiota. Being the most densely populated microbial ecosystem on earth, gut microbiota co-evolved as a key component of human biology, essentially extending the physiological definition of humans. Major advances in microbiome research have shown that the contribution of the intestinal microbiota to the overall health status of the host has been so far underestimated. Human host gut microbial interaction is one of the most significant human health considerations of the present day with relevance for both prevention of disease via microbiota-oriented environmental protection as well as strategies for new therapeutic approaches using microbiota as targets and/or biomarkers. In many aspects, humans are not a complete and fully healthy organism without their appropriate microbiological components. Increasingly, scientific evidence identifies gut microbiota as a key biological interface between human genetics and environmental conditions encompassing nutrition. Microbiota dysbiosis or variation in metabolic activity has been associated with metabolic deregulation (e.g. obesity, inflammatory bowel disease), disease risk factor (e.g. coronary heart disease) and even the aetiology of various pathologies (e.g. autism, cancer), although causal role into impaired metabolism still needs to be established. Metabonomics and Gut Microbiota in Nutrition and Disease serves as a handbook for postgraduate students, researchers in life sciences or health sciences, scientists in academic and industrial environments working in application areas as diverse as health, disease, nutrition, microbial research and human clinical medicine.

Clinical and Basic Neurogastroenterology and Motility

Clinical and Basic Neurogastroenterology and Motility Book
Author : Satish S.C. Rao,Yeong Yeh Lee,Uday C. Ghoshal
Publisher : Academic Press
Release : 2019-12-01
ISBN : 0128130385
Language : En, Es, Fr & De

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Book Description :

Clinical and Basic Neurogastroenterology and Motility is a state-of-the-art, lucidly written, generously illustrated, landmark publication that comprehensively addresses the underlying mechanisms and management of common adult and pediatric motility disorders. These problems affect 50% of the population and include conditions such as dysphagia, achalasia, gastroesophageal reflux disease, gastroparesis, irritable bowel syndrome (IBS), gas and bloating, SIBO, constipation and fecal incontinence. The book brings together international experts and clinician scientists, epitomizing their years of wisdom into a concise yet practical text that is delivered in two distinct sections, basic and clinical. It fulfills a large unmet need, and bridges a long-awaited knowledge gap among trainees, clinicians, scientists, nurses and technicians, earnestly engaged in this field. First of its kind text that covers both basic and clinical aspects, bridging the knowledge gap, and providing a bench to bedside approach for management of common disorders Discusses the latest concepts and basic principles of neurogastroenterology and motility, and how the gut and brain interact in the genesis of functional gastrointestinal and motility disorders Provides an illustrated and practical text on hot topics written by leading adult and pediatric gastroenterology experts across the globe Includes an accompanying more detailed web version of the text with free access to future podcasts

Chronic Pelvic Pain and Pelvic Dysfunctions

Chronic Pelvic Pain and Pelvic Dysfunctions Book
Author : Alessandro Giammò
Publisher : Springer Nature
Release : 2021-10-18
ISBN : 3030563871
Language : En, Es, Fr & De

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Book Description :

Download Chronic Pelvic Pain and Pelvic Dysfunctions book written by Alessandro Giammò, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Gut Microbiome in Health and Disease

The Gut Microbiome in Health and Disease Book
Author : Dirk Haller
Publisher : Springer
Release : 2018-07-27
ISBN : 3319905457
Language : En, Es, Fr & De

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Book Description :

The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.

The Complex Interplay Between Gut Brain Gut Liver and Liver Brain Axes

The Complex Interplay Between Gut Brain  Gut Liver  and Liver Brain Axes Book
Author : Cristina Stasi
Publisher : Academic Press
Release : 2021-04-06
ISBN : 0128219289
Language : En, Es, Fr & De

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Book Description :

The Complex Interplay Between Gut–Brain, Gut–Liver, and Liver–Brain Axes provides current and wide-ranging information in the field of gastrointestinal, liver, and brain interactions that can be used in resolving important clinical issues. This book is systematically split into three distinct sections. The first section introduces the pathophysiology of the gut–brain connection, including the causative effect of the interactions between the gut and brain in gastrointestinal and psychiatric/neurological disorders, and the role of serotonin and its pathways in gastrointestinal disorders. The second section examines the pathophysiology of the gut–liver connection along with the interactions between gut microbiota and liver in chronic liver diseases, with special focus on the role of serotonin and its pathways in hepatic fibrogenesis. Finally, the third section describes the pathophysiology of the liver–brain connection, including the role of gut microbiota in hepatic encephalopathy, as well as dietary and therapeutic interventions that target the gut microbiome. Provides current and wide-ranging knowledge in the field of gastrointestinal, liver, and brain interactions. Resolves important clinical issues concerning gut, liver, and brain interactions. Demonstrates advances in the understanding of the pathophysiology of gastrointestinal and liver diseases.

Gut Microbiota

Gut Microbiota Book
Author : Alper Evrensel,Barış Önen Ünsalver
Publisher : BoD – Books on Demand
Release : 2018-12-12
ISBN : 1789848148
Language : En, Es, Fr & De

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Book Description :

The gut-brain axis has gained considerable attention from different branches of the scientific community in recent years. In this book, scientists from different disciplines present current scientific knowledge on the topic. The interaction between the prokaryote and eukaryote cells stimulates the evolutionary processes, and results in various systemic illnesses such as neuropsychiatric disorders and may help the continuity of health. Nature has provided us with healthy food that builds our pharmacy. This natural pharmacy store may help the body's healing processes through its effects on gut microbiota and the immune system. This book aims to provide the reader with detailed analyses of the current scientific knowledge on the gut-brain axis and its relation with health and disease. We hope that the reader benefits from the presented material.

IAN Textbook of Neurology

IAN Textbook of Neurology Book
Author : Arabinda Mukherjee
Publisher : Jaypee Brothers,Medical Publishers Pvt. Limited
Release : 2018-07-31
ISBN : 9352701798
Language : En, Es, Fr & De

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Book Description :

This book is a comprehensive guide to the diagnosis and management of both common and rare neurological disorders, for practising neurologists and trainees. Divided into twelve chapters, each section is dedicated to a subspecialty of neurology, including movement disorders, headache, epilepsy, neurotoxicology, stroke and more. Topics are presented with a broad overview and include recent advances in the field. Content is further enhanced by tables, clinical images, boxes and flow charts to assist learning. Key points Comprehensive guide to neurological disorders for clinicians and trainees Each section dedicated to a subspecialty of neurology Includes recent advances in the field Highly illustrated with tables, clinical images, boxes and flow charts

The Microbiome and the Brain

The Microbiome and the Brain Book
Author : David Perlmutter
Publisher : CRC Press
Release : 2019-12-06
ISBN : 1351235680
Language : En, Es, Fr & De

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Book Description :

Brain related disorders are among the most challenging health issues of our time. The development of effective therapeutic and preventive strategies for these disorders relies on a comprehensive understanding of the underlying causative mechanisms. And, until recently, these mechanisms have remained somewhat elusive. The newly discovered pivotal role of the intestinal microbiome in brain health, functionality, and resistance to disease is revolutionizing neuroscience. The Microbiome and the Brain, through the contributions of some of the most forward thinking researchers and clinicians in the field, comprehensively reveals the leading edge of our understanding of the fundamental role of gut microbes and their metabolites in a wide array of seemingly diverse brain issues including Alzheimer’s disease, autism, multiple sclerosis, and mood disorders. In addition, mechanisms defining these relationships are explored along with a presentation of the state-of-the-art as it relates to interpretation of relevant laboratory assessments. Finally, novel therapeutic opportunities, derived from this exciting science are presented. Readers will learn: The highly validated relationship between alterations of gut microbes and their metabolites, and risk for Alzheimer’s disease. The important link between autism and intestinal dysbiosis. Appropriate interpretation of available laboratory assessments of the intestinal microbiome. The potential role of fecal microbial transplant in neurological diseases. The influence of diet and other lifestyle choices on the microbiome as it relates to brain health and functionality.

Microbes and the Mind

Microbes and the Mind Book
Author : C.S.M. Cowan,B.E. Leonard
Publisher : Karger Medical and Scientific Publishers
Release : 2021-05-06
ISBN : 331806856X
Language : En, Es, Fr & De

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Book Description :

Interest in the mind-body connection has grown in recent years, with accumulating evidence showing that the gut microbiome can alter behavioral, neural, and psychological outcomes. This publication brings together a group of international experts who are investigating the microbiome and its potential to contribute to the causes and treatment of mental illness. The contributions are not aimed solely at specialists in clinical and experimental neuroscience. They cover a range of key topics, including the role of the microbiome in mental health and specific psychiatric disorders that occur across the lifespan, interactions with the immune system, diet, and pharmacological interventions. Furthermore, the microbial metabolite production and the potential for psychobiotic interventions that target the microbiome to improve mental health outcomes are discussed. This book is unique in its focus on the mechanisms and consequences of the activities of gut microorganisms in mental health and illness, providing expert insight into the current state of the art and important future directions for this emerging area of research. Additionally, it provides an excellent knowledge base for newcomers and a refresher for researchers and clinicians working in the fields of neuroscience, psychology, or psychiatry.

Neuro Immune Connections to Enable Repair in CNS Disorders

Neuro Immune Connections to Enable Repair in CNS Disorders Book
Author : Tim Vanmierlo,Bieke Broux,Jack Van Horssen,Niels Hellings
Publisher : Frontiers Media SA
Release : 2020-10-28
ISBN : 2889660079
Language : En, Es, Fr & De

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Book Description :

Download Neuro Immune Connections to Enable Repair in CNS Disorders book written by Tim Vanmierlo,Bieke Broux,Jack Van Horssen,Niels Hellings, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Psychological Aspects of Inflammatory Bowel Disease

Psychological Aspects of Inflammatory Bowel Disease Book
Author : Simon R. Knowles,Antonina A. Mikocka-Walus
Publisher : Routledge
Release : 2014-09-19
ISBN : 1317807383
Language : En, Es, Fr & De

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Book Description :

In the Western world around 360 in every 100,000 individuals have inflammatory bowel disease (IBD), a relapsing-remitting autoimmune disease that affects the gastrointestinal tract. Its impact on individual functioning across physical and psychosocial domains is significant and psychological distress is a common feature, with research suggesting that active IBD is associated with one of the highest rates of depression and anxiety of all chronic illnesses. Despite the high prevalence of mental health co-morbidities in IBD, psychological illness remains largely undertreated, with studies showing that 60% of IBD patients experiencing mental health problems do not receive adequate help. In this book, Knowles and Mikocka-Walus bring together world experts who practice integrated and holistic approach in their care for IBD patients, to provide an overview of research across a range of topics associated with the biopsychosocial treatment of IBD. Each chapter provides an up-to-date comprehensive consolidation and evaluation of the current literature alongside recommendations for practice. Key themes include: current understanding of the interrelationship of the neurological and biological aspects of IBD common concerns and issues individuals with IBD face exploring challenges across individual life-stages current evidence for psychosocial interventions recommendations for future directions of biopsychosocial work. Psychological Aspects of Inflammatory Bowel Disease: A biopsychosocial approach is a key resource for researchers, practitioners and academics considering psychosocial aspects of the disease and psychological interventions. It will also appeal to health psychologists and mental health practitioners working with clients with IBD, as well as gastroenterologists interested in a comprehensive and holistic approach to IBD management.

Gut Microbiome Related Diseases and Therapies

Gut Microbiome Related Diseases and Therapies Book
Author : Maria Gazouli,George Theodoropoulos
Publisher : Springer Nature
Release : 2021-04-24
ISBN : 3030596427
Language : En, Es, Fr & De

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Book Description :

This book reviews recent knowledge of the role of gut microbiome in health and disease. It covers extensive topics for several diseases, including metabolic-related diseases, allergies, gastrointestinal diseases, psychiatric diseases, and cancer, while also discussing therapeutic approaches by microbiota modification. Comprehensive and cutting-edge, Gut Microbiome-Related Diseases and Therapies deepens a reader’s theoretical expertise in gut microbiome. Graduate and postdoctoral students, medical doctors, and biomedical researchers will benefit from this book.

Nutrition Microbiota and Noncommunicable Diseases

Nutrition  Microbiota and Noncommunicable Diseases Book
Author : Julio Plaza-Díaz
Publisher : MDPI
Release : 2021-01-20
ISBN : 3039369164
Language : En, Es, Fr & De

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Book Description :

Health is defined as “the state of the organism when it functions optimally without evidence of disease”. Surprisingly, the words “microbes” or “microorganism” are missing in this definition. The regulation of gut microbiota is mediated by an enormous quantity of aspects, such as microbiological factors, host characteristics, diet patterns, and environmental variables. Some protective, structural, and metabolic functions have been reported for gut microbiota, and these functions are related to the regulation of homeostasis and host health. Host defense against pathogens is, in part, mediated through gut microbiota action and requires intimate interpretation of the current microenvironment and discrimination between commensal and occasional bacteria. The present Special Issue provides a summary of the progress on the topic of intestinal microbiota and its important role in human health in different populations. This Special Issue will be of great interest from a clinical and public health perspective. Nevertheless, more studies with more samples and comparable methods are necessary to understand the actual function of intestinal microbiota in disease development and health maintenance.