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Glioblastoma Resistance To Chemotherapy

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Glioblastoma Resistance to Chemotherapy Molecular Mechanisms and Innovative Reversal Strategies

Glioblastoma Resistance to Chemotherapy  Molecular Mechanisms and Innovative Reversal Strategies Book
Author : Ramasamy Paulmurugan,Tarik F. Massoud, MD, PhD
Publisher : Academic Press
Release : 2021-07-02
ISBN : 9780128215678
Language : En, Es, Fr & De

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Book Description :

Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an international team of experts on the science and clinical management of glioblastoma chemoresistance. The book discusses topics such as molecular mechanisms of chemoresistance, experimental models to study chemoresistance, chemoresistance to drugs other than Temozolomide, and specific strategies to reverse chemoresistance. Additionally, it encompasses information on how to mitigate chemoresistance by targeted enhancement of p53 function. This book is a valuable resource for cancer researchers, oncologists, neuro-oncologists and other members of the biomedical field. Glioblastoma (GBM) is the most invasive and malignant primary brain tumor in humans with poor survival after diagnosis, therefore it is imperative that molecular and cellular mechanisms behind therapy resistant GBM cells, as well as the therapeutic strategies available to counter the resistance are comprehensively understood. Provides comprehensive, core knowledge related to the entire discipline of glioblastoma chemoresistance, from its many etiological mechanisms, to specific strategies to reverse resistance Presents current information from an international team of experts on the basic science, pre-clinical research, and clinical management of glioblastoma chemoresistance Discusses molecular and cellular mechanisms behind therapy resistant glioblastoma cells, as well as the therapeutic strategies available to counter this resistance

Glioblastoma Resistance to Chemotherapy Molecular Mechanisms and Innovative Reversal Strategies

Glioblastoma Resistance to Chemotherapy  Molecular Mechanisms and Innovative Reversal Strategies Book
Author : Ramasamy Paulmurugan,Tarik F. Massoud
Publisher : Academic Press
Release : 2021-06-18
ISBN : 0128215682
Language : En, Es, Fr & De

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Book Description :

Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an international team of experts on the science and clinical management of glioblastoma chemoresistance. The book discusses topics such as molecular mechanisms of chemoresistance, experimental models to study chemoresistance, chemoresistance to drugs other than Temozolomide, and specific strategies to reverse chemoresistance. Additionally, it encompasses information on how to mitigate chemoresistance by targeted enhancement of p53 function. This book is a valuable resource for cancer researchers, oncologists, neuro-oncologists and other members of the biomedical field. Glioblastoma (GBM) is the most invasive and malignant primary brain tumor in humans with poor survival after diagnosis, therefore it is imperative that molecular and cellular mechanisms behind therapy resistant GBM cells, as well as the therapeutic strategies available to counter the resistance are comprehensively understood. Provides comprehensive, core knowledge related to the entire discipline of glioblastoma chemoresistance, from its many etiological mechanisms, to specific strategies to reverse resistance Presents current information from an international team of experts on the basic science, pre-clinical research, and clinical management of glioblastoma chemoresistance Discusses molecular and cellular mechanisms behind therapy resistant glioblastoma cells, as well as the therapeutic strategies available to counter this resistance

New Targeting in The Reversal of Resistant Glioblastomas

New Targeting in The Reversal of Resistant Glioblastomas Book
Author : Ali Syed Arbab
Publisher : Academic Press
Release : 2021-03-18
ISBN : 0128232765
Language : En, Es, Fr & De

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Book Description :

New Targeting in The Reversal of Resistant Glioblastomas discusses alternative treatment strategies that not only target tumor cells but also target the tumor microenvironment, metabolic pathways and interaction of cytokines in tumor cells. The current treatment for primary and recurrent glioblastomas is failing because clinicians are not considering the effect of bone marrow derived cells to the development of resistance to clinically practiced therapies. This book helps readers rethink treatment strategies to successfully fight glioblastomas. It is a valuable resource for cancer researchers, clinicians, graduate students and other members of the biomedical field. Explains the effect of bone marrow derived cells on the development of resistance to clinically practiced therapies Provides information on the availability of alternate therapies for recurrent glioblastoma when standard practices have failed Discusses targeting tumor microenvironment using available FDA approved drugs as an alternative treatment strategy for glioblastoma

Cumulated Index Medicus

Cumulated Index Medicus Book
Author : Anonim
Publisher : Unknown
Release : 1995
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cumulated Index Medicus book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Cancer Research

Cancer Research Book
Author : Anonim
Publisher : Unknown
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cancer Research book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Cancer Chemotherapy Reports

Cancer Chemotherapy Reports Book
Author : Anonim
Publisher : Unknown
Release : 1964
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cancer Chemotherapy Reports book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Anticancer Research

Anticancer Research Book
Author : Anonim
Publisher : Unknown
Release : 2009
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Type 1 Sodium Hydrogen Exchanger NHE1 in Human Glioblastoma Cell Lines

Type 1 Sodium Hydrogen Exchanger NHE1 in Human Glioblastoma Cell Lines Book
Author : Jane Ann Roscoe
Publisher : Unknown
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Type 1 Sodium Hydrogen Exchanger NHE1 in Human Glioblastoma Cell Lines book written by Jane Ann Roscoe, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Pathology and Genetics of Tumours of the Nervous System

Pathology and Genetics of Tumours of the Nervous System Book
Author : International Agency for Research on Cancer
Publisher : International Agency for Research on Cancer
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The second edition of this concise reference book was prepared by 106 authors from 21 countries and covers the neuro-oncological literature until January 2000. Diagnostic criteria, pathological features and associated genetic alterations are described in a strictly disease-oriented manner. Sections on more than 70 neoplasms and their variants include ICD-O codes, incidence, age and sex distribution, location, clinical signs and symptoms, pathology, genetics and predictive factors. New disease entities include the chordoid glioma of the third ventricle and the cerebellar liponeurocytoma. Inherited tumor syndromes involving the nervous system are dealt with in a separate chapter, combining diagnostic criteria, pathology and genetics.

Integration Interaction of Oncologic Growth

Integration Interaction of Oncologic Growth Book
Author : Gary G. Meadows
Publisher : Springer Science & Business Media
Release : 2005-05-25
ISBN : 9781402034138
Language : En, Es, Fr & De

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Book Description :

A unique book on the interactions and interrelationships between tumor and host that modulate progression and metastasis. Several authors emphasize targeting the host rather than the tumor itself for therapeutic intervention to control cancer.

Excerpta Medica

Excerpta Medica Book
Author : Anonim
Publisher : Unknown
Release : 1991
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Annual Meeting Proceedings

Annual Meeting Proceedings Book
Author : American Society of Clinical Oncology. Meeting
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Annual Meeting Proceedings book written by American Society of Clinical Oncology. Meeting, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Chemoradiation

Chemoradiation Book
Author : Marshall Flam
Publisher : Unknown
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Chemoradiation book written by Marshall Flam, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Drug Resistance as a Biochemical Target in Cancer Chemotherapy

Drug Resistance as a Biochemical Target in Cancer Chemotherapy Book
Author : Takashi Tsuruo,M. Ogawa
Publisher : Unknown
Release : 1992
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The development of drug resistance hinders the effectiveness of cancer chemotherapy. This book, drawing upon recent molecular biological and biochemical studies that are helping shed light on the molecular mechanisms of drug resistance, summarizes recent clinical and preclinical studies.

The Journal of Neuroscience

The Journal of Neuroscience Book
Author : Anonim
Publisher : Unknown
Release : 2009
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Journal of Neuroscience book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

NMC

NMC Book
Author : Anonim
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Contains the proceedings of the 12th- annual meeting of the Japan Neurosurgical Society.

International Journal of Oncology

International Journal of Oncology Book
Author : Anonim
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download International Journal of Oncology book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Textbook of Neuro oncology

Textbook of Neuro oncology Book
Author : Mitchel S. Berger,Michael Prados
Publisher : Saunders
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Presents an outstanding review of state-of-the-art basic science, including epidemiology as well as molecular and cellular biology. This volume describes the very latest approaches to diagnostic imaging and pathologic classification; covers the newest treatment techniques, from neurosurgery through radiation therapy, chemotherapy, neuro-interventional techniques, immunotherapy, and gene therapy, and discusses functional outcomes and clinical trial findings. It explores all of the most challenging neurologic cancers that clinicians face, including meningiomas, chordomas and chondrosarcomas of the cranial base, benign and malignant peripheral nerve tumors, medulloblastomas, neurocutaneous syndromes, ependymomas, and malignant rhabdoid tumors. Includes a thorough section on Pediatric Neuro-Oncology and offers more than 800 crisp clinical and pathological photos to facilitate diagnosis and treatment.

Enhanced Chemotherapy by Drug Conjugation and Release from Polymer

Enhanced Chemotherapy by Drug Conjugation and Release from Polymer Book
Author : Victoria Ying
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

In the collagen gel experiment, 9L spheroids were more like tumors than 9L cells, CM-PEG-CPT reduced spheroid areas and migrations more than CPT, and CM-PEG-CPT variants were equally effective in reducing areas and migrations.