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Genetic Steroid Disorders 2e

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Growth Disorders 2E

Growth Disorders 2E Book
Author : Chris Kelnar,Martin Savage,Paul Saenger,Chris Cowell
Publisher : CRC Press
Release : 2007-06-29
ISBN : 1444113739
Language : En, Es, Fr & De

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Book Description :

Linear growth is a biological process of fundamental importance to the physical and psychological make-up of a child and adolescent but which can be subject to a number of interruptions and disorders. The management and treatment of patients with growth disorders constitues a major, and important, part of practice in clinical paediatrics, while in public health terms growth assessment remains one of the most useful indices of health and economic well being in both developed and the developing world. This book approaches growth and its disorders from both a physiological and pathophysiological standpoint. The book outlines in detail the fundamental biological mechanisms of normal and abnormal linear growth, how to assess growth accurately fundamental to the early detection of abnormality and, importantly, how to manage disorders leading to short and tall stature, and disorders of the timing of puberty. Throughout, emphasis is given on achieving a satisfactory outcome for the child and parent by keeping them fully informed as to what is possible from a particular treatment strategy. The result is a wide-ranging and balanced account of this challenging field drawing on the expertise of a team of international specialists from a variety of backgrounds.

Annotated alphabetical list

Annotated alphabetical list Book
Author : National Institute on Alcohol Abuse and Alcoholism (U.S.)
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Annotated alphabetical list book written by National Institute on Alcohol Abuse and Alcoholism (U.S.), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Excerpta medica Section 22 Human genetics

Excerpta medica  Section 22  Human genetics Book
Author : Anonim
Publisher : Unknown
Release : 1985
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Excerpta medica Section 22 Human genetics book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Growth Disorders 2E

Growth Disorders 2E Book
Author : Chris Kelnar,Martin Savage,Paul Saenger,Chris Cowell
Publisher : CRC Press
Release : 2007-06-29
ISBN : 0340812400
Language : En, Es, Fr & De

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Book Description :

Linear growth is a biological process of fundamental importance to the physical and psychological make-up of a child and adolescent but which can be subject to a number of interruptions and disorders. The management and treatment of patients with growth disorders constitues a major, and important, part of practice in clinical paediatrics, while in public health terms growth assessment remains one of the most useful indices of health and economic well being in both developed and the developing world. This book approaches growth and its disorders from both a physiological and pathophysiological standpoint. The book outlines in detail the fundamental biological mechanisms of normal and abnormal linear growth, how to assess growth accurately fundamental to the early detection of abnormality and, importantly, how to manage disorders leading to short and tall stature, and disorders of the timing of puberty. Throughout, emphasis is given on achieving a satisfactory outcome for the child and parent by keeping them fully informed as to what is possible from a particular treatment strategy. The result is a wide-ranging and balanced account of this challenging field drawing on the expertise of a team of international specialists from a variety of backgrounds.

Role of Protein Protein Interactions in Metabolism Genetics Structure Function 2nd Edition

Role of Protein Protein Interactions in Metabolism  Genetics  Structure  Function  2nd Edition Book
Author : Amit V. Pandey,Colin J. Henderson,Yuji Ishii,Michel Kranendonk,Wayne L. Backes,Ulrich M. Zanger
Publisher : Frontiers Media SA
Release : 2018-06-20
ISBN : 2889454916
Language : En, Es, Fr & De

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Book Description :

Genetic variations may change the structure and function of individual proteins as well as affect their interactions with other proteins and thereby impact metabolic processes dependent on protein-protein interactions. For example, cytochrome P450 proteins, which metabolize a vast array of drugs, steroids and other xenobiotics, are dependent on interactions with redox and allosteric partner proteins for their localization, stability, (catalytic) function and metabolic diversity (reactions). Genetic variations may impact such interactions by changing the splicing and/or amino acid sequence which in turn may impact protein topology, localization, post translational modifications and three dimensional structure. More generally, research on single gene defects and their role in disease, as well as recent large scale sequencing studies suggest that a large number of genetic variations may contribute to disease not only by affecting gene function or expression but also by modulating complex protein interaction networks. The aim of this research topic is to bring together researchers working in the area of drug, steroid and xenobiotic metabolism who are studying protein-protein interactions, to describe their recent advances in the field. We are aiming for a comprehensive analysis of the subject from different approaches including genetics, proteomics, transcriptomics, structural biology, biochemistry and pharmacology. Of particular interest are papers dealing with translational research describing the role of novel genetic variations altering protein-protein interaction. Authors may submit original articles, reviews and opinion or hypothesis papers dealing with the role of protein-protein interactions in health and disease. Potential topics include, but are not limited to: • Role of protein-protein interactions in xenobiotic metabolism by cytochrome P450s and other drug metabolism enzymes. • Role of classical and novel interaction partners for cytochrome P450-dependent metabolism which may include interactions with redox partners, interactions with other P450 enzymes to form P450 dimers/multimers, P450-UGT interactions and proteins involved in posttranslational modification of P450s. • Effect of genetic variations (mutations and polymorphisms) on metabolism affected by protein-protein interactions. • Structural implications of mutations and polymorphisms on protein-protein interactions. • Functional characterization of protein-protein interactions. • Analysis of protein-protein interaction networks in health and disease. • Regulatory mechanisms governing metabolic processes based on protein-protein interactions. • Experimental approaches for identification of new protein-protein interactions including changes caused by mutations and polymorphisms.

Amern Handbk Psychi V3 2e

Amern Handbk Psychi V3 2e Book
Author : Silvano Arieti,Eugene B. Brody
Publisher : Unknown
Release : 1974-07-11
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Amern Handbk Psychi V3 2e book written by Silvano Arieti,Eugene B. Brody, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Hormone Behavior Relations of Clinical Importance

Hormone Behavior Relations of Clinical Importance Book
Author : Robert H. Rubin,Donald W. Pfaff
Publisher : Academic Press
Release : 2010-03-16
ISBN : 9780080958002
Language : En, Es, Fr & De

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Book Description :

A single volume of 41 articles, Hormone/Behavior Relations of Clinical Importance is an authoritative selection of relevant chapters from the Hormones Brain and Behavior 2e MRW, the most comprehensive source of neuroendocrinological information assembled to date (AP July 2009). The study of hormones as they impact the brain and, subsequently, behavior is a central topic in neuroscience, endocrinology and psychiatry. This volume offers an overview of neuroendocrinological topics, approaching the subject from the perspective of hormone-brain function, hormone-behavior relations, sex differences, and the impact on various diseases/pathologies. Many basic human behavioral functions are subject to the influence of hormones - sexual orientation, the experience of pain, fertility, immunity - as are clinical conditions such as diabetes, substance abuse disorder, eating disorders, PTSD, TBI, pain, Alzheimer's, stress/anxiety, affective disorders, and more. There is considerable commercial clinical potential in the study of hormones - drug companies are currently developing a Cholecystokinin (hormonal peptide) booster to reduce appetite in those who suffer from sever obesity, and catamenial epilepsy (features seizure exacerbation in relation to the menstrual cycle) is resistant to treatment by standard antiepileptic medications, but may be hormonally controlled. These issues and more are covered, and there is simply no other current single-volume reference with such comprehensive coverage and depth. Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 150 figures (50 in color). A collection of articles reviewing our fundamental knowledge of neuroendocrinology, the book provides an essential, affordable reference for researchers, clinicians and graduate students in the area. - Offering outstanding scholarship, each chapter is written by an expert in the topic area and approximately 25% of chapters are written by international contributors (7 countries represented) - Provides more fully vetted expert knowledge than any existing work with broad appeal for the US, UK and Europe, accurately crediting the contributions to research in those regions - Heavily illustrated with 150 figures, approximately 50 in color, presenting the material in the most visually useful form for the reader - Fully explores various clinical conditions associated with the hormones and the brain (PTSD, TBI, Stress & Anxiety, eating disorders, diabetes, addictive disorders, Alzheimer's, affective disorders) - Broad coverage of disorders makes the volume relevant to clinicians as well as researchers and basic scientists

Alphabetical index

Alphabetical index Book
Author : National Institute on Alcohol Abuse and Alcoholism (U.S.)
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Alphabetical index book written by National Institute on Alcohol Abuse and Alcoholism (U.S.), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Endocrine Society Annual Meeting Program and Abstracts

The Endocrine Society   Annual Meeting  Program and Abstracts Book
Author : Endocrine Society. Meeting,Endocrine Society
Publisher : Unknown
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Endocrine Society Annual Meeting Program and Abstracts book written by Endocrine Society. Meeting,Endocrine Society, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Chemical Abstracts

Chemical Abstracts Book
Author : Anonim
Publisher : Unknown
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Chemical Abstracts book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Annotated hierarchy

Annotated hierarchy Book
Author : National Institute on Alcohol Abuse and Alcoholism (U.S.)
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Annotated hierarchy book written by National Institute on Alcohol Abuse and Alcoholism (U.S.), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Harrison s Gastroenterology and Hepatology 2e

Harrison s Gastroenterology and Hepatology  2e Book
Author : Dan Longo,Anthony S. Fauci
Publisher : McGraw-Hill Prof Med/Tech
Release : 2013-03-22
ISBN : 0071814892
Language : En, Es, Fr & De

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Book Description :

Gastroenterology – as only Harrison’s can cover it Featuring a superb compilation of chapters related to gastroenterology that appear in Harrison’s Principles of Internal Medicine, Eighteenth Edition, this concise, full-color clinical companion delivers the latest knowledge in the field backed by the scientific rigor and authority that have defined Harrison’s. You will find content from renowned editors and contributors in a carry-anywhere presentation that is ideal for the classroom, clinic, ward, or exam/certification preparation. Features Complete coverage of must-know gastroenterology and hepatology topics, including cardinal manifestations of disease, differential diagnosis and diagnostic evaluation, management of diseases and disorders, obesity, nutrition, and eating disorders Reflects the most current advances in genetics, cell biology, pathophysiology, and treatment Integration of pathophysiology with clinical management 107 high-yield questions and answers drawn from Harrison’s Principles of Internal Medicine Self-Assessment and Board Review, 18e Content updates and new developments since the publication of Harrison’s Principles of Internal Medicine, 18e 60 chapters written by physicians who are recognized experts in the field of gastroenterology Helpful appendix of laboratory values of clinical importance

Oxford Dictionary of Biochemistry and Molecular Biology

Oxford Dictionary of Biochemistry and Molecular Biology Book
Author : Anthony David Smith
Publisher : Oxford University Press, USA
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The Oxford Dictionary of Biochemistry and Molecular Biology provides a comprehensive survey of current biochemistry and molecular biology. The entries are short but informative, providing up-to-date information on a broad range of topics. There are over 17,000 main entries, which give details of biochemical substances and the processes in which they are involved, define methods and concepts in molecular biology, and give definitions of biochemical symbols and abbreviations. Alternative names for biochemical compounds are listed and will refer the reader to the main entry where the internationally recommended biochemical nomenclature is used. Entries also include the structures and activities of chemical compounds of interest to biochemists, with over 800 illustrations of chemical structures. Brief biographical details are provided for relevant Nobel Laureates and for eponyms.

Genetic Mechanisms of Sexual Development

Genetic Mechanisms of Sexual Development Book
Author : H. Lawrence Vallet,Ian H. Porter
Publisher : Unknown
Release : 1979
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Genetic Mechanisms of Sexual Development book written by H. Lawrence Vallet,Ian H. Porter, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Pediatric Practice Endocrinology 2nd Edition

Pediatric Practice  Endocrinology  2nd Edition Book
Author : Michael S. Kappy,David B. Allen,Mitchell E. Geffner
Publisher : McGraw Hill Professional
Release : 2014-05-22
ISBN : 0071813187
Language : En, Es, Fr & De

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Book Description :

The go-to guide for managing endocrine problems in children – completely updated for today’s practice Part of the Pediatric Practice series, Pediatric Practice: Endocrinology is an outstanding clinical analysis and decision-making tool for those treating endocrine problems in children. Featuring an innovative problem-oriented approach, this well-illustrated, full-color guide skillfully integrates pathophysiology with clinical management. Numerous figures illustrate the principles of normal and abnormal physiology and treatment rationale and effects. Since an understanding of the clinical manifestations and treatments of endocrine disorders begins with knowledge of concepts of hormone action and principles of feedback control, the first chapter, "General Concepts and Physiology," links genetics, cell biology, and physiology with pathophysiology to provide a clear and approachable overview of endocrine systems. Subsequent chapters discuss disorders of growth, puberty, thyroid and adrenal glands, sex development, calcium and bone metabolism, water homeostasis, and carbohydrate metabolism and its comorbidities. In this second edition, contributing authors have updated all chapters. Important additions include sections on genetics for the endocrinologist in the general concepts chapter, an overview of the physiology and treatment of metabolic syndrome and dyslipidemia in the obesity chapter, and the addition of a new chapter on enteric hormones. Features of the Pediatric Practice Series The Pediatric Practice series simplifies the care of pediatric patients by delivering: Tips that tell you what you must know--and what you must do--at every stage of care Diagnostic and treatment algorithms Signs/Symptoms and Differential Diagnosis boxes When to Refer boxes, which examine all the relevant clinical considerations Diagnostic Tests--with a realistic emphasis on the right tests to order Medical Treatment coverage that includes drugs, dosages, and administration in an easy-to-read tabular format Convenient icons and a consistent chapter design Numerous clinical color photos and didactic diagrams

Gene Therapy

Gene Therapy Book
Author : Nancy Smyth Templeton,D. D. Lasic
Publisher : CRC Press
Release : 2000-06-15
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This text covers all aspects of gene therapy, including basic principles, viral and nonviral delivery systems, targeted diseases, regulatory issues, and FDA requirements. It investigates genetic bullets to block HIV-1 replication and genetic guns to deliver antiviral agents.

Current Catalog

Current Catalog Book
Author : Anonim
Publisher : Unknown
Release : 1989
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

First multi-year cumulation covers six years: 1965-70.

Testosterone

Testosterone Book
Author : Eberhard Nieschlag,Hermann M. Behre
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3642721850
Language : En, Es, Fr & De

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Book Description :

The first edition of "Testosterone: Action, Deficiency, Substitu tion" was published in 1990. Since then our understanding of the hormone that turns males into men has tremendously increased. Therefore, the editors felt that a second extended edition of the book is warranted in order to summarize established and recent findings in the field and to present the reader with an up-to-date is reflected by the textbook. The increased mass of knowledge growth of the volume from 14 to 20 chapters. In the updated edition the biochemistry and metabolism of androgens have been complemented by extensive information on the molecular biology of the androgen receptor and its disorders. The key role of testosterone in spermatogenesis is now better de fined. We have a more complete understanding of the psychotro pic effects of testosterone and know so much about the different target organs and functions that individual chapters deal with testosterone and the prostate, lipids and the cardiovascular sys tem, hair, bones and muscles. The general chapter on pharmacol ogy and clinical uses of testosterone, in particular in male hypo gonadism, is extended by pharmacokinetic studies on testoster one preparations and individual substitution modalities using testosterone esters as well as implants and advanced trans dermal applications. The physiologic basis and possible clinical applica tions of testosterone in non-gonadal diseases, in male senes cence, in hormonal male contraception and in transsexuals are discussed. The last chapter describes the role of "investigative" steroid biochemistry applied to tracking anabolic steroid abuse.

International Research Centers Directory

International Research Centers Directory Book
Author : Anonim
Publisher : Unknown
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download International Research Centers Directory book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Disorders of Hair Growth

Disorders of Hair Growth Book
Author : Elise A. Olsen
Publisher : McGraw-Hill
Release : 2003
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The only comprehensive book on the subject of hair loss! Highly illustrated, with 250 new color photographs, this resource covers the basic science, diagnosis, and treatment of all problems related to hair. Conditions covered include childhood hair loss, excessive body hair, various types of adult balding, and loss due to medical conditions, trauma, and medications. The new Second Edition emphasizes various new diagnosis and treatment methods including popular, recently approved remedies.