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Genes Brain Function And Behavior

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Genes Brain Function and Behavior

Genes  Brain Function  and Behavior Book
Author : Douglas Wahlsten
Publisher : Academic Press
Release : 2019-03-14
ISBN : 012812833X
Language : En, Es, Fr & De

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Book Description :

Genes, Brain Function, and Behavior offers a concise description of the nervous system that processes sensory input and initiates motor movements. It reviews how behaviors are defined and measured, and how experts decide when a behavior is perturbed and in need of treatment. Behavioral disorders that are clearly related to a defect in a specific gene are reviewed, and the challenges of understanding complex traits such as intelligence, autism and schizophrenia that involve numerous genes and environmental factors are explored. New methods of altering genes offer hope for treating or even preventing difficulties that arise in our genes. This book explains what genes are, what they do in the nervous system, and how this impacts both brain function and behavior. Presents essential background, facts, and terminology about genes, brain function, and behavior Builds clear explanations on this solid foundation while minimizing technical jargon Explores in depth several single-gene and chromosomal neurological disorders Derives lessons from these clear examples and highlights key lessons in boxes Examines the intricacies of complex traits that involve multiple genetic and environmental factors by applying lessons from simpler disorders Explains diagnosis and definition Includes a companion website with Powerpoint slides and images for each chapter for instructors and links to resources

Genes Brain and Behavior

Genes  Brain  and Behavior Book
Author : Paul Rodney McHugh
Publisher : Lippincott Williams & Wilkins
Release : 1991
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Applications of concepts & tech. in medical genetics to the study diagnosis & control of neurologic & psychiatric dis.

Molecular Genetic and Statistical Techniques for Behavioral and Neural Research

Molecular Genetic and Statistical Techniques for Behavioral and Neural Research Book
Author : Robert T. Gerlai
Publisher : Academic Press
Release : 2018-04-24
ISBN : 0128041161
Language : En, Es, Fr & De

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Book Description :

Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior Written and edited by leading international experts

Human Language

Human Language Book
Author : Peter Hagoort
Publisher : MIT Press
Release : 2019-10-29
ISBN : 0262042630
Language : En, Es, Fr & De

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Book Description :

A unique overview of the human language faculty at all levels of organization. Language is not only one of the most complex cognitive functions that we command, it is also the aspect of the mind that makes us uniquely human. Research suggests that the human brain exhibits a language readiness not found in the brains of other species. This volume brings together contributions from a range of fields to examine humans' language capacity from multiple perspectives, analyzing it at genetic, neurobiological, psychological, and linguistic levels. In recent decades, advances in computational modeling, neuroimaging, and genetic sequencing have made possible new approaches to the study of language, and the contributors draw on these developments. The book examines cognitive architectures, investigating the functional organization of the major language skills; learning and development trajectories, summarizing the current understanding of the steps and neurocognitive mechanisms in language processing; evolutionary and other preconditions for communication by means of natural language; computational tools for modeling language; cognitive neuroscientific methods that allow observations of the human brain in action, including fMRI, EEG/MEG, and others; the neural infrastructure of language capacity; the genome's role in building and maintaining the language-ready brain; and insights from studying such language-relevant behaviors in nonhuman animals as birdsong and primate vocalization. Section editors Christian F. Beckmann, Carel ten Cate, Simon E. Fisher, Peter Hagoort, Evan Kidd, Stephen C. Levinson, James M. McQueen, Antje S. Meyer, David Poeppel, Caroline F. Rowland, Constance Scharff, Ivan Toni, Willem Zuidema

Regulation of Gene Expression and Brain Function

Regulation of Gene Expression and Brain Function Book
Author : Paul J. Harrison
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3642784585
Language : En, Es, Fr & De

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Book Description :

Gene expression converts the information coded by our genes into proteins. These determine the structure and function of an organ such as the brain. Itis therefore an essential process, linking molecular genetics with neurochemistry and behavioral neuroscience. This volume presents a didactic approach to the understanding of the basic processes of gene expression and their involvement in certain brain diseases, such asAlzheimer's disease and schizophrenia. Generously illustrated, the contributions provide a valuable outline of this key aspect of molecular neurobiology and clinical neuroscience.

Genes Brain Function and Behavior

Genes  Brain Function  and Behavior Book
Author : Douglas Wahlsten
Publisher : Academic Press
Release : 2019-03-01
ISBN : 0128128321
Language : En, Es, Fr & De

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Book Description :

Genes, Brain Function, and Behavior offers a concise description of the nervous system that processes sensory input and initiates motor movements. It reviews how behaviors are defined and measured, and how experts decide when a behavior is perturbed and in need of treatment. Behavioral disorders that are clearly related to a defect in a specific gene are reviewed, and the challenges of understanding complex traits such as intelligence, autism and schizophrenia that involve numerous genes and environmental factors are explored. New methods of altering genes offer hope for treating or even preventing difficulties that arise in our genes. This book explains what genes are, what they do in the nervous system, and how this impacts both brain function and behavior. Presents essential background, facts, and terminology about genes, brain function, and behavior Builds clear explanations on this solid foundation while minimizing technical jargon Explores in depth several single-gene and chromosomal neurological disorders Derives lessons from these clear examples and highlights key lessons in boxes Examines the intricacies of complex traits that involve multiple genetic and environmental factors by applying lessons from simpler disorders Explains diagnosis and definition Includes a companion website with Powerpoint slides and images for each chapter for instructors and links to resources

Genes Brains and Emotions

Genes  Brains  and Emotions Book
Author : Andrei C. Miu,Judith R. Homberg,Klaus-Peter Lesch
Publisher : Oxford University Press, USA
Release : 2019-04-04
ISBN : 0198793014
Language : En, Es, Fr & De

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Book Description :

The study of emotions has rapidly expanded in recent decades, incorporating interdisciplinary research on the genetic underpinnings and neural mechanisms of emotion. This has involved a wide range of methods from as varied fields as behavioral genetics, molecular biology, and cognitive neuroscience, and has allowed researchers to start addressing complex multi-level questions such as: what is the role of genes in individual differences in emotions and emotional vulnerability to psychopathology, and what are the neural mechanisms through which genes and experience shape these emotion? Genes, Brain, and Emotions: Interdisciplinary and translational perspectives offers a comprehensive account of this interdisciplinary field of research, bridging psychology, genetics, and neuroscience, with rich sections dedicated to methods, cognitive and biological mechanisms, and psychopathology. Written by leading researchers who have each inspired new research directions and innovated methods and concepts, this book will be of interest to anyone working or studying in the field of affective science, whether they be behavioural geneticists, psychologists and psychiatrists, or cognitive neuroscientists.

Behavioral Neurogenomics

Behavioral Neurogenomics Book
Author : Elisabeth B. Binder,Torsten Klengel
Publisher : Springer Nature
Release : 2019-12-12
ISBN : 3030312658
Language : En, Es, Fr & De

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Book Description :

This book provides a unique overview on the most recent developments in initially diverse areas of behavioral genomic research that now start to intertwine to provide more detailed insights into the complex nature of behavior in health and disease. It focuses on our current understanding of genetic and epigenetic mechanisms of brain function and how they contribute to the complex formation of behavioral traits and psychiatric disorders. Readers experience diverse perspectives of the contributing authors starting from the genetic viewpoint and the effort to establish functional connection between genetic variants and behavioral phenotypes. Particular attention is given to the broad spectrum of epigenetic mechanisms and behavior. The chapter 'Role of MicoRNAs in Anxiety and Anxiety-Related Disorders' is available open access under a CC BY 4.0 license at link.springer.com

Hormones Brain and Behavior

Hormones  Brain and Behavior Book
Author : Marian Joels
Publisher : Academic Press
Release : 2016-12-22
ISBN : 9780128035924
Language : En, Es, Fr & De

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Book Description :

Hormones, Brain and Behavior, Third Edition offers a state-of-the-art overview of hormonally-mediated behaviors, including an extensive discussion of the effects of hormones on insects, fish, amphibians, birds, rodents, and humans. Entries have been carefully designed to provide a valuable source of information for students and researchers in neuroendocrinology and those working in related areas, such as biology, psychology, psychiatry, and neurology. This third edition has been substantially restructured to include both foundational information and recent developments in the field. Continuing the emphasis on interdisciplinary research and practical applications, the book includes articles aligned in five main subject sections, with new chapters included on genetic and genomic techniques and clinical investigations. This reference provides unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics. The topics cover an unusual breadth (from molecules to ecophysiology), ranging from basic science to clinical research, making this reference of interest to a broad range of scientists in a variety of fields. Comprehensive and updated coverage of a rapidly growing field of researchUnique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular geneticsCovers an unusual breadth of topics and subject fields, ranging from molecules to ecophysiology, and from basic science to clinical researchIdeal resource for interdisciplinary learning and understanding in the fields of hormones and behavior

Lateralized Brain Functions Methods in Human and Non Human Species

Lateralized Brain Functions  Methods in Human and Non Human Species Book
Author : Lesley J. Rogers,Giorgio Vallortigara
Publisher : Neuromethods
Release : 2019-02
ISBN : 9781493982837
Language : En, Es, Fr & De

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Book Description :

Download Lateralized Brain Functions Methods in Human and Non Human Species book written by Lesley J. Rogers,Giorgio Vallortigara, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Neurobiology of Criminal Behavior

The Neurobiology of Criminal Behavior Book
Author : Anthony Walsh,Jonathan D. Bolen
Publisher : Ashgate Publishing, Ltd.
Release : 2012
ISBN : 9781409438410
Language : En, Es, Fr & De

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Book Description :

Explores the neurobiology of crime from a biosocial perspective. While the brain and its various mechanisms are the main focus of this work, the authors look at criminal behaviour guided by Nikolas Tinbergen's famous Four Questions: Causation, Development, Phylogeny, and Function.

Lateralized Brain Functions

Lateralized Brain Functions Book
Author : Lesley Rogers,Giorgio Vallortigara
Publisher : Humana Press
Release : 2016-12-05
ISBN : 9781493967230
Language : En, Es, Fr & De

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Book Description :

This volume explores both simple and sophisticated techniques used in the study of different types of lateralization of brain and behavior. Research in this field increases our understanding of various brain functions in humans, other vertebrate species, and invertebrates. The book is divided into five parts: behavioral methods; neurobiological methods; electroencephalographic, imaging, and neuro-stimulation methods; genetic techniques; and development of lateralization. Part I addresses measuring lateralization by scoring behavior induced by inputs to one or the other side of the brain in a range of species. Part II covers neurobiological methods used to reveal lateralization, such as lesion studies, electrophysiology and pharmacology, early gene expression, and new optogenetic methods. Part III looks at imaging techniques, electroencephalographic techniques, and transcranial stimulation to reveal lateralization. Part IV describes techniques used to study the role of genes in the development and establishment of brain asymmetry in humans and other species. Lastly, Part V refers to methods used in the study of development of lateralization through the manipulation of sensory exposure, hormone levels, and in model systems. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory. Cutting-edge and thorough, Lateralized Brain Function: Methods in Human and Non-Human Species is a valuable resource for investigating lateralization in a broad range of species and provides excellent advice for both new and veteran researchers.

Handbook of Molecular Genetic Techniques for Brain and Behavior Research

Handbook of Molecular Genetic Techniques for Brain and Behavior Research Book
Author : Wim E. Crusio,R.T. Gerlai
Publisher : Elsevier
Release : 1999-10-18
ISBN : 9780080536866
Language : En, Es, Fr & De

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Book Description :

The book gives a broad overview of recombinant DNA techniques for the behavioral neuroscientist, with illustrative examples of applications. Species covered include rodents (mainly mice), Drosophila melanogaster, Caenorhabditis elegans and Danio rerio. Experimental techniques required to characterize the behavioral phenotypes of mutant animals is provided. Several aspects of novel molecular-genetic techniques are overviewed and possible research strategies are explained. The sections of the book start with general descriptions of techniques followed by illustrative examples. It is divided into six sections. Section 1, bioinformatics and genomics research. Section 2, top-down strategies, where the researcher starts with the phenotype and then analyzes the associated genes; bottom-up strategies, where the physiological chain leading to a phenotype is analyzed starting from the gene product. Section 3, transgenic approaches in rodents including overexpressing foreign genes and gene-targeting; systemic manipulation approaches directly targeting the central nervous system and methods used with invertebrates. Section 4, methods used to evaluate relevant behavioral phenotypes, including learning and aggression. Section 5, examples on molecular brain research in man. Section 6, ethical aspects of research in this field.

Hormone Behavior Relations of Clinical Importance

Hormone Behavior Relations of Clinical Importance Book
Author : Robert H. Rubin,Donald W. Pfaff
Publisher : Academic Press
Release : 2010-03-16
ISBN : 9780080958002
Language : En, Es, Fr & De

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Book Description :

A single volume of 41 articles, Hormone/Behavior Relations of Clinical Importance is an authoritative selection of relevant chapters from the Hormones Brain and Behavior 2e MRW, the most comprehensive source of neuroendocrinological information assembled to date (AP July 2009). The study of hormones as they impact the brain and, subsequently, behavior is a central topic in neuroscience, endocrinology and psychiatry. This volume offers an overview of neuroendocrinological topics, approaching the subject from the perspective of hormone-brain function, hormone-behavior relations, sex differences, and the impact on various diseases/pathologies. Many basic human behavioral functions are subject to the influence of hormones - sexual orientation, the experience of pain, fertility, immunity - as are clinical conditions such as diabetes, substance abuse disorder, eating disorders, PTSD, TBI, pain, Alzheimer's, stress/anxiety, affective disorders, and more. There is considerable commercial clinical potential in the study of hormones - drug companies are currently developing a Cholecystokinin (hormonal peptide) booster to reduce appetite in those who suffer from sever obesity, and catamenial epilepsy (features seizure exacerbation in relation to the menstrual cycle) is resistant to treatment by standard antiepileptic medications, but may be hormonally controlled. These issues and more are covered, and there is simply no other current single-volume reference with such comprehensive coverage and depth. Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 150 figures (50 in color). A collection of articles reviewing our fundamental knowledge of neuroendocrinology, the book provides an essential, affordable reference for researchers, clinicians and graduate students in the area. - Offering outstanding scholarship, each chapter is written by an expert in the topic area and approximately 25% of chapters are written by international contributors (7 countries represented) - Provides more fully vetted expert knowledge than any existing work with broad appeal for the US, UK and Europe, accurately crediting the contributions to research in those regions - Heavily illustrated with 150 figures, approximately 50 in color, presenting the material in the most visually useful form for the reader - Fully explores various clinical conditions associated with the hormones and the brain (PTSD, TBI, Stress & Anxiety, eating disorders, diabetes, addictive disorders, Alzheimer's, affective disorders) - Broad coverage of disorders makes the volume relevant to clinicians as well as researchers and basic scientists

Hormones Brain and Behavior Online

Hormones  Brain and Behavior Online Book
Author : Anonim
Publisher : Academic Press
Release : 2002-06-18
ISBN : 008088783X
Language : En, Es, Fr & De

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Book Description :

Hormones, Brain, and Behavior, Second Edition is a comprehensive work discussing the effect of hormones on the brain and, subsequently, behavior. This major reference work has 109 chapters covering a broad range of topics with an extensive discussion of the effects of hormones on insects, fish, amphibians, birds, rodents, and humans. To truly understand all aspects of our behavior, we must take every influence (including the hormonal influences) into consideration. Donald Pfaff and a number of well-qualified editors examine and discuss how we are influenced by hormonal factors, offering insight, and information on the lives of a variety of species. Hormones, Brain, and Behavior offers the reader comprehensive coverage of growing field of research, with a state-of-the-art overview of hormonally-mediated behaviors. This reference provides unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics. The topics cover an unusual breadth (from molecules to ecophysiology), ranging from basic science to clinical research, making this reference of interest to a broad range of scientists in a variety of fields. Available online exclusively via ScienceDirect. A limited edition print version is also available. Comprehensive coverage of a growing field of research Unique treatment of all major vertebrate and invertebrate model systems with excellent opportunites for relating behavior to molecular genetics Covers an unusual breadth ranging from molecules to ecophysiology, and from basic science to clinical research

Sleep Neuronal Plasticity and Brain Function

Sleep  Neuronal Plasticity and Brain Function Book
Author : Peter Meerlo,Ruth M. Benca,Ted Abel
Publisher : Springer
Release : 2015-05-18
ISBN : 3662468786
Language : En, Es, Fr & De

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Book Description :

This book reviews current knowledge on the importance of sleep for brain function, from molecular mechanisms to behavioral output, with special emphasis on the question of how sleep and sleep loss ultimately affect cognition and mood. It provides an extensive overview of the latest insights in the role of sleep in regulating gene expression, synaptic plasticity and neurogenesis and how that in turn is linked to learning and memory processes. In addition, readers will learn about the potential clinical implications of insufficient sleep and discover how chronically restricted or disrupted sleep may contribute to age-related cognitive decline and the development of psychiatric disorders such as schizophrenia and depression. The book consists of 19 chapters, written by experts in basic sleep research and sleep medicine, which together cover a wide range of topics on the importance of sleep and consequences of sleep disruption. This book will be of interest to students, researchers and clinicians with a general interest in brain function or a specific interest in sleep.

Principles of Behavioral Genetics

Principles of Behavioral Genetics Book
Author : Robert RH Anholt,Trudy F. C. Mackay
Publisher : Academic Press
Release : 2009-09-21
ISBN : 9780080919898
Language : En, Es, Fr & De

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Book Description :

Principles of Behavioral Genetics provides an introduction to the fascinating science that aims to understand how our genes determine what makes us tick. It presents a comprehensive overview of the relationship between genes, brain, and behavior. Introductory chapters give clear explanations of basic processes of the nervous system and fundamental principles of genetics of complex traits without excessive statistical jargon. Individual chapters describe the genetics of social interactions, olfaction and taste, memory and learning, circadian behavior, locomotion, sleep, and addiction, as well as the evolution of behavior. Whereas the focus is on genetics, neurobiological and ecological aspects are also included to provide intellectual breadth. The book uses examples that span the gamut from classical model organisms to non-model systems and human biology, and include both laboratory and field studies. Samples of historical information accentuate the text to provide the reader with an appreciation of the history of the field. This book will be a valuable resource for future generations of scientists who focus on the field of behavioral genetics. Defines the emerging science of behavioral genetics Engagingly written by two leading experts in behavioral genetics Clear explanations of basic quantitative genetic, neurogenetic and genomic applications to the study of behavior Numerous examples ranging from model organisms to non-model systems and humans Concise overviews and summaries for each chapter

Sex Differences in the Brain From Genes to Behavior

Sex Differences in the Brain From Genes to Behavior Book
Author : Jill B. Becker,Karen J. Berkley,Nori Geary,Elizabeth Hampson,James P. Herman,Elizabeth Young
Publisher : Oxford University Press, USA
Release : 2007-12-04
ISBN : 9780195311587
Language : En, Es, Fr & De

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Book Description :

Sex is a fundamentally important biological variable. Recent years have seen significant progress in the integration of sex in many aspects of basic and clinical research, including analyses of sex differences in brain function. Significant advances in the technology available for studying the endocrine and nervous systems are now coupled with a more sophisticated awareness of the interconnections of these two communication systems of the body. A thorough understanding of the current knowledge, conceptual approaches, methodological capabilities, and challenges is a prerequisite to continued progress in research and therapeutics in this interdisciplinary area.Sex Differences in the Brain provides scientists with the basic tools for investigating sex differences in brain and behavior and insight into areas where important progress in understanding physiologically relevant sex differences has already been made. This book was edited and co-authored by members of the Isis Fund Network on Sex, Gender, Drugs and the Brain, sponsored by the Society for Womens Health Research.The book is arranged in three parts. The first part of the book introduces the study of sex differences in the brain, with an overview of how the brain, stress systems, and pharmacogenetics differ in males and females and how this information is important for the study of behavior and neurobiology of both genders. The second part presents examples of sex differences in neurobiology and behavior from both basic and clinical research perspectives, covering both humans and nonhuman animals. The final part discusses sex differences in the neurobiology of disease and neurological disorders.For interested individuals as well as those who are considering conducting research at the intersections of endocrinology, neuroscience, and other areas of biomedicine, the study of sex differences offers exciting and challenging questions and perspectives. This book is intended as a guide and resource for clinicians, scientists, and students.

Behavioral and Neural Genetics of Zebrafish

Behavioral and Neural Genetics of Zebrafish Book
Author : Robert T. Gerlai
Publisher : Academic Press
Release : 2020-04-03
ISBN : 012817529X
Language : En, Es, Fr & De

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Book Description :

Behavioral and Neural Genetics of Zebrafish assembles the state-of-the-art methodologies and current concepts pertinent to their neurobehavioral genetics. Discussing their natural behavior, motor function, learning and memory, this book focuses on the fry and adult zebrafish, featuring a comprehensive account of modern genetic and neural methods adapted to, or specifically developed for, Danio rerio. Numerous examples of how these behavioral methods may be utilized for disease models using the zebrafish are presented, as is a section on bioinformatics and "big-data" related questions. Provides the most comprehensive snapshot of the fast-evolving zebrafish neurobehavior genetics field Describes behavioral, genetic and neural methods and concepts for use in adult and larval zebrafish Features examples of zebrafish models of human central nervous system disorders Discusses bioinformatics questions pertinent to zebrafish neurobehavioral genetics

Techniques for the Genetic Analysis of Brain and Behavior

Techniques for the Genetic Analysis of Brain and Behavior Book
Author : D. Goldowitz,D. Wahlsten
Publisher : Elsevier Science Limited
Release : 1992
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The goal of this book is to provide a neurobehavioral context for the ever-growing list of single and multiple genes that play a role in brain structure and function. The chapters present strategies and techniques for the rigorous analysis of the genetic bases of brain and behavior, and discusses the practical and theoretical means to address these topics and provide the researcher with fine techniques for dissecting the genomic components of brain structure and behavioral function. This volume concentrates on techniques and approaches that have been largely developed with the house mouse, while providing a glimpse of genetic research with other species, such as the fruit fly, nematode worm and seaslug. Given the aim of doing genetic analysis of brain and behavior, this volume is an excellent overview of current techniques and recent innovations.