Skip to main content

Gene Therapy Of Cancer

In Order to Read Online or Download Gene Therapy Of Cancer Full eBooks in PDF, EPUB, Tuebl and Mobi you need to create a Free account. Get any books you like and read everywhere you want. Fast Download Speed ~ Commercial & Ad Free. We cannot guarantee that every book is in the library!

Gene Therapy of Cancer

Gene Therapy of Cancer Book
Author : Wolfgang Walther,Ulrike Stein
Publisher : Springer Science & Business Media
Release : 2000
ISBN : 1592590861
Language : En, Es, Fr & De

GET BOOK

Book Description :

In Gene Therapy of Cancer: Methods and Protocols, Wolfgang Walther and Ulrike Stein survey the rapidly evolving field cancer gene therapy and provide a broad array of leading-edge protocols for the delivery of therapeutic genes into tumors. Described in step-by-step fashion and enriched with each author's own practical tips, these readily reproducible methods are currently being widely applied in cancer gene therapy investigations, including immunotherapy and tumor vaccination, suicide gene therapy, antioncogene therapy, and antisense and ribozyme gene therapy. Representative strategies are provided for gene targeting and for viral or nonviral gene delivery in cancer therapy, as well as a significant number of clinical protocols for the development of novel cancer gene therapies. Gene Therapy of Cancer: Methods and Protocols offers basic and clinical researchers a broad ranging overview and collection of the most recent advances in gene transfer techniques. Written by leading international authorities, its readily reproducible, cutting-edge methods constitute today's most valuable tools for the study of cancer gene therapy in both the laboratory and clinical trials.

Cancer Gene Therapy

Cancer Gene Therapy Book
Author : David T. Curiel,Joanne T. Douglas
Publisher : Springer Science & Business Media
Release : 2007-11-03
ISBN : 1592597858
Language : En, Es, Fr & De

GET BOOK

Book Description :

A complete introduction and guide to the latest developments in cancer gene therapy-from bench to bedside. The authors comprehensively review the anticancer genes and gene delivery methods currently available for cancer gene therapy, including the transfer of genetic material into the cancer cells, stimulation of the immune system to recognize and eliminate cancer cells, and the targeting of the nonmalignant stromal cells that support their growth. They also thoroughly examine the advantages and limitations of the different therapies and detail strategies to overcome obstacles to their clinical implementation. Topics of special interest include vector-targeting techniques, the lessons learned to date from clinical trials of cancer gene therapy, and the regulatory guidelines for future trials. Noninvasive techniques to monitor the extent of gene transfer and disease regression during the course of treatment are also discussed.

Gene Therapy for Cancer

Gene Therapy for Cancer Book
Author : Kelly K. Hunt,Stephan A. Vorburger,Stephen G. Swisher
Publisher : Springer Science & Business Media
Release : 2007-10-26
ISBN : 159745222X
Language : En, Es, Fr & De

GET BOOK

Book Description :

The three sections of this volume present currently available cancer gene therapy techniques. Part I describes the various aspects of gene delivery. In Part II, the contributors discuss strategies and targets for the treatment of cancer. Finally, in Part III, experts discuss the difficulties inherent in bringing gene therapy treatment for cancer to the clinic. This book will prove valuable as the volume of preclinical and clinical data continues to increase.

Gene Therapy of Cancer

Gene Therapy of Cancer Book
Author : Edmund C. Lattime,Stanton L. Gerson
Publisher : Academic Press
Release : 2013-08-28
ISBN : 0123946328
Language : En, Es, Fr & De

GET BOOK

Book Description :

Gene therapy as a treatment for cancer is at a critical point in its evolution. Exciting new developments in gene targeting and vector technology, coupled with results from the first generation of preclinical and clinical studies have led to the design and testing of new therapeutic approaches. The Third Edition of Gene Therapy of Cancer provides crucial updates on the basic and applied sciences of gene therapy. It offers a comprehensive assessment of the field including the areas of suicide gene therapy, oncogene and suppressor gene targeting, immunotherapy, drug resistance gene therapy, and the genetic modification of stem cells. Researchers at all levels of development, from basic laboratory investigators to clinical practitioners, will find this book to be instructive. Cancer gene therapy, like cancer therapy in general, is evolving rapidly, testing new concepts, targets and pathways, evoking new technologies, and passing new regulatory hurdles. Its essence, however, has not changed: the hope and challenges of returning altered genes to normal, using targeted gene expression to alter the function of both tumor and microenvironment, and in some cases normal cells, and delivering functionally important genes to specific cell types to increase sensitivity to killing or to protect normal cells from cancer therapies. In some instances, gene therapy for cancer forms a continuum from gene repair through the use of molecularly modified cells; the use of viral and non-viral vector based gene delivery to both tumor and tumor microenvironment; the use of viral and gene based vaccines; and development of new gene-based therapeutics. The unique mechanistically chosen vector platforms are at the heart of this technology because they allow for direct and selective cell death and transient to sustained delivery of vaccine molecules or molecules that affect the microenvironment, vasculature, or the immune response. Explains the underlying cancer biology necessary for understanding proposed therapeutic approaches Presents in-depth description of targeting systems and treatment strategies Covers the breadth of gene therapy approaches including immunotherapeutic, drug resistance,oncolytic viruses, as well as regulatory perspectives from both the NCI and FDA

Gene Based Therapies for Cancer

Gene Based Therapies for Cancer Book
Author : Jack A. Roth
Publisher : Springer Science & Business Media
Release : 2010-07-28
ISBN : 9781441961020
Language : En, Es, Fr & De

GET BOOK

Book Description :

Cancer gene therapy is a novel therapy that targets the underlying genetic defects in the cancer cell. Progress in this field has been rapid and gene therapy promises to further extend personalized cancer treatment. In this volume leading experts have contributed their experience in developing gene therapies for a variety of cancers. Translational gene therapy approaches are emphasized. Chapters include discussions of specific gene delivery technologies as well as their application to various cancers with extensive discussions of ongoing clinical trials. This information should be useful to both students, fellows, and experienced scientists with an interest in this rapidly developing area.

Gene Therapy and Cancer Research Focus

Gene Therapy and Cancer Research Focus Book
Author : Rebecca N. Campbell
Publisher : Nova Publishers
Release : 2008
ISBN : 9781600219702
Language : En, Es, Fr & De

GET BOOK

Book Description :

Genes, which are carried on chromosomes, are the basic physical and functional units of heredity. Genes are specific sequences of bases that encode instructions on how to make proteins. Although genes get a lot of attention, it's the proteins that perform most life functions and even make up the majority of cellular structures. When genes are altered so that the encoded proteins are unable to carry out their normal functions, genetic disorders can result. Gene therapy is an experimental treatment that involves introducing genetic material into a person's cells to fight disease. Gene therapy is being studied in clinical trials for many different types of cancer and for numerous other diseases. The volume presents significant new research results in this promising field.

Cancer Gene Therapy by Viral and Non viral Vectors

Cancer Gene Therapy by Viral and Non viral Vectors Book
Author : Malcolm Brenner,Mien-Chie Hung
Publisher : John Wiley & Sons
Release : 2014-03-17
ISBN : 9781118501627
Language : En, Es, Fr & De

GET BOOK

Book Description :

Provides expert, state-of-the-art insight into the current progress of viral and non-viral gene therapy Translational medicine has opened the gateway to the era of personalized or precision medicine. No longer a one-size-fits-all approach, the treatment of cancer is now based on an understanding of underlying biologic mechanisms and is increasingly being tailored to the molecular specificity of a tumor. This book provides a comprehensive overview of the pertinent molecular discoveries in the cancer field and explains how these are being used for gene-based cancer therapies. Designed as a volume in the Translational Oncology book series, Cancer Gene Therapy by Viral and Non-viral Vectors deals with the practice of gene-therapy, with reference to vectors for gene expression and gene transfer, as well as viral therapy. It covers the history and current and future applications of gene transfer in cancer, and provides expert insight on the progress of viral and non-viral gene therapy with regard to delivery system, vector design, potential therapeutic genes, and principles and regulations for cancer gene therapy. Presented in three parts, Cancer Gene Therapy by Viral and Non-viral Vectors covers: Delivery Systems * Translational Cancer Research: Gene Therapy by Viral and Non-viral Vectors * Retroviruses for Cancer Therapy * DNA Plasmids for Non-viral Gene Therapy of Cancer * Cancer Therapy with RNAi delivered by Non-viral Membrane/Core Nanoparticles Targeted Expression * Cancer Gene Therapy by Tissue-specific and Cancer-targeting Promptors * MicroRNAs as Drugs and Drug Targets in Cancer Principles of Clinical Trials in Gene Therapy * Regulatory issues for Manufacturers of Viral Vectors and Vector-transduced Cells for Phase I/II Trials * US Regulations Governing Clinical Trials in Gene Therapy * Remaining Obstacles to the Success of Cancer Gene Therapy Focusing on speeding the process in clinical cancer care by bringing therapies as quickly as possible from bench to bedside, Cancer Gene Therapy by Viral and Non-viral Vectors is an absolutely vital book for physicians, clinicians, researchers, and students involved in this area of medicine.

The Development of Human Gene Therapy

The Development of Human Gene Therapy Book
Author : Professor at Center for Molecular Genetics Department of Paediatrics Theodore Friedmann,Theodore Friedmann
Publisher : CSHL Press
Release : 1999
ISBN : 9780879695286
Language : En, Es, Fr & De

GET BOOK

Book Description :

The idea of human gene therapy was accepted by the medical community and society at large long before believable clinical benefits began to emerge. In this book, some of the fields most distinguished contributors chronicle the evolution of this momentous direction for medicine, illustrating how imaginative concepts shaped the development of technologies and brought the daring new idea to its current position of imminent practical success. This is a book designed to endure as clinical advances accumulate, a clear-eyed work of reference that will anchor the further development of this revolution in therapy. It is an essential addition to libraries of clinical medicine, biotechnology, and public policy, and a resource that no laboratory investigator with an interest in the biology of gene transfer should be without.

Cancer

Cancer Book
Author : Joseph Panno
Publisher : Infobase Publishing
Release : 2009-01-01
ISBN : 0816067325
Language : En, Es, Fr & De

GET BOOK

Book Description :

Examines what is known about cancer cells and current cancer research.

Journal of the National Cancer Institute

Journal of the National Cancer Institute Book
Author : Anonim
Publisher : Unknown
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Journal of the National Cancer Institute book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Gene Therapy in Cancer

Gene Therapy in Cancer Book
Author : Grace W. Redberry
Publisher : Nova Publishers
Release : 2005
ISBN : 9781594542886
Language : En, Es, Fr & De

GET BOOK

Book Description :

Genes, which are carried on chromosomes, are the basic physical and functional units of heredity. Genes are specific sequences of bases that encode instructions on how to make proteins. Although genes get a lot of attention, it's the proteins that perform most life functions and even make up the majority of cellular structures. When genes are altered so that the encoded proteins are unable to carry out their normal functions, genetic disorders can result. Gene therapy is an experimental treatment that involves introducing genetic material into a person's cells to fight disease. Gene therapy is being studied in clinical trials for many different types of cancer and for numerous other diseases. This new book offers the latest research in a field bursting with new developments, hope and expectations.

Gene Therapy

Gene Therapy Book
Author : Kam Man Hui
Publisher : World Scientific Publishing Company Incorporated
Release : 1994
ISBN : 9789810216542
Language : En, Es, Fr & De

GET BOOK

Book Description :

With advances in our understanding of the molecular biology of human diseases and the development of efficient gene transfer techniques, the treatment of such diseases as cancer and infectious disease using gene therapy has progressed from a distant prospect to a distinct possibility in a very short time. The development of gene transfer methods which are suitable for different forms of therapy has been a major topic of research over the past several years. A common goal of this research has been to achieve the efficient delivery of genes into cells. The successful implementation of gene transfer as a cure for diseases, however, will continue to require the translation of preclinical studies in gene therapy into effective clinical protocols. This volume outlines the latest developments in cancer treatment using various gene delivery systems, which include cytokine gene transfer, the delivery of anti-ras DNA by retroviral vector and the injection of allogeneic HLA DNA via liposomes. Several of these molecular approaches have recently been approved by the US FDA as human clinical trial protocols in order to assess their therapeutic efficiency and safety for cancer treatment. Further developments in recombinant DNA technology within this field should ultimately lead to dramatic improvements in the practice of medicine.

Gene Therapy

Gene Therapy Book
Author : Kenneth W. Culver
Publisher : Mary Ann Liebert
Release : 1994
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Gene Therapy book written by Kenneth W. Culver, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Textbook of Gene Therapy

Textbook of Gene Therapy Book
Author : Kewal K. Jain
Publisher : Seattle ; Toronto : Hogrefe & Huber
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

During the past eight years following initial gene therapy experiments, more than 200 clinical protocols have been submitted worldwide and more than 2000 patients have been treated. Although a lot remains to be accomplished before gene therapy becomes a standard medical practice, enough information has accumulated to justify a textbook on the subject. Some of the procedures and products are expected to enter the marketplace and medical practice by the year 2000. The public is very much aware of the potential of gene therapy and the medical profession should prepare itself for the new developments by learning about the basics and applications of these techniques. Much of there-search has been conducted in the bio-pharmaceutical industry by gene therapy companies and the commercial opportunities for gene therapy are enormous. A large segment of the society thus has an interest in gene therapy. This book presents a unique critical review of the tremendous progress which has been made in this field. The textbook is an effort to bring a wide range of important developments together in an accessible format. This book is aimed at physicians, gene therapists, molecular biologists, nurse practitioners and students in these fields, as well as other healthcare professionals interested in developments in the field of gene therapy and its impact, both short- and long-term, on the practice of medicine. Industrial executives planning long-term strategies in gene therapy will find this handy textbook to be a comprehensive source of information on the subject and the companies involved in developing it. Prof. K. K. Jain is a neurosurgeon trained in Canada and the United States. He has heldacademic positions in major medical centers around the world. For the last decade, he has been a consultant to a number of major biopharmaceutical companies and now runs his own biotechnology company specializing in gene therapy research and documentation.

Gene Therapy

Gene Therapy Book
Author : Gavin Brooks
Publisher : Unknown
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Considers the genetic basis of disease and gene therapies, concentrating in detail on specific genetic illnesses, such as AIDS, cancer and cardiovascular diseases, and their treatment. This text should be of interest to pharmacists and to those involved in the biological or medical sciences.

Molecular Aspects of Cancer and Its Therapy

Molecular Aspects of Cancer and Its Therapy Book
Author : Andrzej Mackiewicz,Pravinkumar B. Sehgal,P. B. Sehgal
Publisher : Springer Science & Business Media
Release : 1998
ISBN : 9783764357245
Language : En, Es, Fr & De

GET BOOK

Book Description :

This book highlights recent progress in the molecular, cellular and immunological mechanisms that contribute to the pathophysiology of cancer and the design of therapeutic modalities based upon these molecular insights. This volume serves to introduce the general reader as well as the cancer specialist to personalized perspectives of particular topics in cancer research by leading research groups in the field. The combination of a "review"-approach with a more research-oriented approach in discussions of specific research topics provides a stimulating and, hopefully, forward-looking volume which serves to update selected aspects of cancer research today. This combination will be useful to both the beginner as well as the more advanced biomedical scientist.

Recent Advances in Cancer Research and Therapy

Recent Advances in Cancer Research and Therapy Book
Author : Xin-Yuan Liu,Sidney Pestka,Yu-Fang Shi
Publisher : Elsevier
Release : 2012
ISBN : 0123978335
Language : En, Es, Fr & De

GET BOOK

Book Description :

Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Because of this, in the past decade, rapid progress in the field of cancer treatment has been seen. Recent Advances in Cancer Research and Therapy reviews in specific details some of the most effective and promising treatments developed in research centers worldwide. While referencing advances in traditional therapies and treatments such as chemotherapy, this book also highlights advances in biotherapy including research using Interferon and Super Interferon, HecI based and liposome based therapy, gene therapy, and p53 based cancer therapy. There is also a discussion of current cancer research in China including traditional Chinese medicine. Written by leading scientists in the field, this book provides an essential insight into the current state of cancer therapy and treatment. Includes a wide range of research areas including a focus on biotherapy and the development of novel cancer therapeutic strategies. Formatted for a broad audience including all working in researching cancer treatments and therapies. Discusses special traits and results of Chinese cancer research.

Gene Therapy for Prostate Cancer

Gene Therapy for Prostate Cancer Book
Author : Pejman Cohan
Publisher : Unknown
Release : 1995
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Gene Therapy for Prostate Cancer book written by Pejman Cohan, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Concepts in Gene Therapy

Concepts in Gene Therapy Book
Author : Michael Strauss,John A. Barranger
Publisher : De Gruyter
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Concepts in Gene Therapy book written by Michael Strauss,John A. Barranger, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Preclinical Evaluation of Adenovirus mediated Suicide Gene Therapy for Prostate Cancer and Multimodality Imaging of Viral Biodistribution and Transgene Expression

Preclinical Evaluation of Adenovirus mediated Suicide Gene Therapy for Prostate Cancer and Multimodality Imaging of Viral Biodistribution and Transgene Expression Book
Author : Mai H. Johnson
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Preclinical Evaluation of Adenovirus mediated Suicide Gene Therapy for Prostate Cancer and Multimodality Imaging of Viral Biodistribution and Transgene Expression book written by Mai H. Johnson, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.