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Future Directions In Biocatalysis

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Future Directions in Biocatalysis

Future Directions in Biocatalysis Book
Author : Tomoko Matsuda
Publisher : Elsevier
Release : 2017-08-11
ISBN : 0444637508
Language : En, Es, Fr & De

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Book Description :

Future Directions in Biocatalysis, Second Edition, presents the future direction and latest research on how to utilize enzymes, i.e., natural catalysts, to make medicines and other necessities for humans. It emphasizes the most important and unique research on biocatalysis instead of simply detailing the ABC’s on the topic. This book is an indispensable tool for new researchers in the field to help identify specific needs, start new projects that address current environmental concerns, and develop techniques based on green technology. It provides invaluable hints and clues for conducting new research on enzymes, with final sections outlining future directions in biocatalysis further expanding the science into new applications. Gives future directions in the area of biocatalysis research Presents research topics based on their uniqueness, originality, and novelty Includes many explanatory figures to demonstrate concepts to both organic chemists and biochemists Shows that there is no boundary between organic chemistry and biochemistry

Future Directions in Biocatalysis

Future Directions in Biocatalysis Book
Author : Tomoko Matsuda
Publisher : Elsevier
Release : 2011-08-11
ISBN : 9780080545264
Language : En, Es, Fr & De

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Book Description :

In Future Directions in Biocatalysis the important topics within biocatalysis and enzymatic catalysis for organic synthesis are described for both experts and non-experts. This books focuses particularly on reactions under development at present and on future advances in the field. Consisting of four sections, this book examines enzymatic reactions under unusual conditions, unique biocatalytic reactions, synthesis of valuable compounds using biocatalysis and the latest molecular biology methods for biocatalysis. Each chapter deals with a specific theme and includes a summary of each area as well as the present state and future direction of research. * Describes methods for solving environmental issues through biocatalysis * Presents the integrated fields of biochemistry and organic chemistry * Unique research topics with high originality

Applied Bioengineering

Applied Bioengineering Book
Author : Toshiomi Yoshida
Publisher : John Wiley & Sons
Release : 2017-01-06
ISBN : 3527800603
Language : En, Es, Fr & De

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Book Description :

A comprehensive overview of the topic, highlighting recent developments, ongoing research trends and future directions. Experts from Europe, Asia and the US cover five core areas of imminent importance to the food, feed, pharmaceutical and water treatment industries in terms of sustainable and innovative processing and production. In the field of enzyme engineering, they summarize historic developments and provide an overview of molecular enzyme engineering, while also discussing key principles of microbial process engineering, including chapters on process development and control. Further sections deal with animal and plant cell culture engineering. The final section of the book deals with environmental topics and highlights the application of bioengineering principles in waste treatment and the recovery of valuable resources. With its cutting-edge visions, extensive discussions and unique perspectives, this is a ready reference for biotechnologists, bioengineers, bioengineers, biotechnological institutes, and environmental chemists.

The Chemical Engineer

The Chemical Engineer Book
Author : Anonim
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Chemical Engineer book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biocatalysis Based on Heme Peroxidases

Biocatalysis Based on Heme Peroxidases Book
Author : Eduardo Torres,Marcela Ayala
Publisher : Springer Science & Business Media
Release : 2010-08-20
ISBN : 9783642126277
Language : En, Es, Fr & De

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Book Description :

The last systematic description of heme peroxidases was published in 1999 by Brian Dunford, from the University of Alberta in Canada. The book Heme per- idases covers discussion on three-dimensional structure, reaction mechanism, kinetics, and spectral properties of representative enzymes from bacterial, plant, fungal, and animal origin. Since 1999, vast information on basic but also applied aspects of heme peroxidases has been generated. We believe fusion of these two aspects will bene?t research of those dedicated to development of biocatalytic process. The aim of this book is to present recent advances on basic aspects such as evolution, structure–function relation, and catalytic mechanism, as well as applied aspects, such as bioreactor and protein engineering, in order to provide the tools for rational design of enhanced biocatalysts and biocatalytic processes. The book does not include an exhaustive listing of references but rather a selected collection to enrich discussion and to allow envisioning future directions for research. This book is organized in three parts. In Part I, current knowledge of structure and mechanism of peroxidases is covered. From the molecular phylogeny, going through the in?uence of structural factors over oxidative ability to the molecular mechanism of catalysis, the authors intend to provide an understanding of per- idases at the molecular level. The understanding of the fundamental behavior of peroxidases will allow further adequation, design, and/or optimization of pero- dase-based catalysis to a particular process. In Part II, research on potential applications of peroxidases in several ?elds is presented and discussed.

Science of Synthesis Biocatalysis in Organic Synthesis Vol 3

Science of Synthesis  Biocatalysis in Organic Synthesis Vol  3 Book
Author : Kurt Faber
Publisher : Georg Thieme Verlag
Release : 2015-03-11
ISBN : 3131766611
Language : En, Es, Fr & De

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Book Description :

The three Science of Synthesis volumes on "Biocatalysis in Organic Synthesis" present the possibilities offered by modern biocatalysis to the nonspecialist academic and industrial readership who are involved in practical organic synthesis. The goal of the reference work is to start a new wave of enthusiasm for biocatalysis in the broader community and to give an overview of the field. As all SoS volumes, "Biocatalysis in Organic Synthesis" offers critical reviews of organic transformations by experts, including experimental procedures. The organization is based on the type of reaction performed under biocatalysis. Volume 3 begins by describing oxidation. A chapter on dihydroxylation is followed by reviews of alkane oxidation. Oxidations of alcohols, carbonyl compounds, and heteroatoms are also covered, as are halogenations. The use of biocatalysts in total synthesis, cascade reactions, and the development of large-scale processes are considered. Finally, emerging trends are outlined.

Biocatalysis for the Pharmaceutical Industry

Biocatalysis for the Pharmaceutical Industry Book
Author : Junhua (Alex) Tao,Guo-Qiang Lin,Andreas Liese
Publisher : John Wiley & Sons
Release : 2009-07-23
ISBN : 0470823151
Language : En, Es, Fr & De

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Book Description :

Biocatalysis is rapidly evolving into a key technology for the discovery and production of chemicals, especially in the pharmaceutical industry, where high yielding chemo-, regio-, and enantioselective reactions are critical. Taking the latest breakthroughs in genomics and proteomics into consideration, Biocatalysis for the Pharmaceutical Industry concisely yet comprehensively discusses the modern application of biocatalysis to drug discovery, development, and manufacturing. Written by a team of leading experts, the book offers deep insight into this cutting edge field. Covers a wide range of topics in a systematic manner with an emphasis on industrial applications Provides a thorough introduction to the latest biocatalysts, modern expression hosts, state-of-the-art directed evolution, high throughput screening, and bioprocess engineering Addresses frontier subjects such as emerging enzymes, metabolite profiling, combinatorial biosynthesis, metabolic engineering, and autonomous enzymes for the synthesis and development of chiral molecules, drug metabolites, and semi-synthetic medicinal compounds and natural product analogs Highlights the impact of biocatalysis on green chemistry Contains numerous graphics to illustrate concepts and techniques Biocatalysis for the Pharmaceutical Industry is an essential resource for scientists, engineers, and R&D policy makers in the fine chemical, pharmaceutical, and biotech industries. It is also an invaluable tool for academic researchers and advanced students of organic and materials synthesis, chemical biology, and medicinal chemistry.

Asymmetric Synthesis in Organophosphorus Chemistry

Asymmetric Synthesis in Organophosphorus Chemistry Book
Author : Oleg I. Kolodiazhnyi
Publisher : John Wiley & Sons
Release : 2016-12-19
ISBN : 3527341501
Language : En, Es, Fr & De

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Book Description :

Authored by one of the leading experts in the field, this is the only comprehensive overview of chiral organophosphorus compounds, from asymmetric synthesis to catalysis and pharmacological applications. As such, this unique reference covers the chemical background as well as spectroscopical analysis of phosphorus compounds, and thoroughly describes all the various synthetic strategies for these substances. Metal-, organo- and biocatalyzed reactions for the introduction of phosphorus are explained as are asymmetric oxidation and reduction methods for the preparation of all possible oxidation states of phosphorus. The text also includes industrial applications for these compounds. Of particular interest to chemists working in the field of asymmetric synthesis, as well as to the pharmaceutical industry due to the increasing number of phosphorous-containing drugs.

Applied Biocatalysis

Applied Biocatalysis Book
Author : Harvey W. Blanch,Douglas S. Clark
Publisher : CRC Press
Release : 2021-05-30
ISBN : 1000444651
Language : En, Es, Fr & De

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Book Description :

This volume addresses the key topics: nonaqueous enzymology in general and protein design for organic solvents in particular, and enzymatic synthesis of carbon-carbon bonds, novel oligosaccharides, and modified steroids. It is a valuable source to experienced as well as potential users of enzymes.

Modern Biocatalysis

Modern Biocatalysis Book
Author : Gavin Williams,Mélanie Hall
Publisher : Royal Society of Chemistry
Release : 2018-05-31
ISBN : 1788014537
Language : En, Es, Fr & De

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Book Description :

The synergy between synthetic biology and biocatalysis is emerging as an important trend for future sustainable processes. This book reviews all modern and novel techniques successfully implemented in biocatalysis, in an effort to provide better performing enzymatic systems and novel biosynthetic routes to (non-)natural products. This includes the use of molecular techniques in protein design and engineering, construction of artificial metabolic pathways, and application of computational methods for enzyme discovery and design. Stress is placed on current ‘hot’ topics in biocatalysis, where recent advances in research are defining new grounds in enzyme-catalyzed processes. With contributions from leading academics around the world, this book makes a ground-breaking contribution to this progressive field and is essential reading for graduates and researchers investigating (bio)catalysis, enzyme engineering, chemical biology, and synthetic biology.

Phosphorus Chemistry I

Phosphorus Chemistry I Book
Author : Jean-Luc Montchamp
Publisher : Springer
Release : 2015-03-06
ISBN : 3319154737
Language : En, Es, Fr & De

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Book Description :

Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.

Biocatalysts for Industry

Biocatalysts for Industry Book
Author : Jonathan S. Dordick
Publisher : Springer Science & Business Media
Release : 2013-03-09
ISBN : 1475745974
Language : En, Es, Fr & De

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Book Description :

The application of enzymes or whole cells (fermentatively active or resting; microbial, plant, or animal) to carry out selective transformations of commercial importance is the central theme of industrial biocatalysis. Traditionally, biocatalysis has been in the domain of the life scientist or biochemical engineer. However, recent advances in this field have enabled biocatalytic processes to compete head on with, and in some cases out perform, conventional chemical processing. Chemo-biocatalytic systems are being developed thereby combining the most attractive features of bio catalysts, namely high specificity, with those of chemical catalysts, such as high reactivities and wide substrate specificities. Hence, synthetic chemists and chemical engineers are now beginning to use biocatalysts as highly selective reagents in chemical synthesis and processing. This book is about biocatalysts and their past, present, and potential applications in the food, pharmaceutical, and chemical industries. The con cept of the book did not emanate from a meeting. Rather, it is a compila tion of selected examples where biocatalysis either has already made a significant impact in the aforementioned industries, or has the potential to make a substantial contribution. I have been fortunate to have assembled contributions from world-class researchers in the field of biocatalysis. Their timely contributions are sincerely appreciated.

Biocatalysis and Agricultural Biotechnology

Biocatalysis and Agricultural Biotechnology Book
Author : Ching T. Hou,Jei-Fu Shaw
Publisher : CRC Press
Release : 2009-04-27
ISBN : 9781420077070
Language : En, Es, Fr & De

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Book Description :

Worldwide energy and food crises are spotlighting the importance of bio-based products – an area many are calling on for solutions to these shortages. Biocatalysis and Agricultural Biotechnology encapsulates the cutting-edge advances in the field with contributions from more than 50 international experts comprising sectors of academia, industry, and government research institutes, a virtual Who’s Who among biocatalysis scientists. Created Under the Editorial Guidance of Leading Biotechnology Experts With the aid of numerous graphs and illustrations, this authoritative reference documents such important advances as: Cloning and characterization of Kennedy pathway acyltransferases Engineering of plants for industrial uses New approaches from acquired tolerance to the biotic and abiotic stress of economically important crops This comprehensive text also explores a variety of bio-based industrial products, including: The modification of enzyme character through gene manipulation The biocatalytic synthesis of chiral intermediates for drug development The use of Omega-3 phospholipid nano capsules as effective forms for transporting immune response modifiers Providing in-depth reviews of this ancient field and its modern-day advances, Biocatalysis and Agricultural Biotechnology is an invaluable lab reference for teachers, graduate students, and industrial scientists conducting research in the biosciences.

Applied Biocatalysis

Applied Biocatalysis Book
Author : Andreas Liese,Lutz Hilterhaus,Ulrich Kettling,Garabed Antranikian
Publisher : John Wiley & Sons
Release : 2016-09-13
ISBN : 3527336699
Language : En, Es, Fr & De

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Book Description :

This reference book originates from the interdisciplinary research cooperation between academia and industry. In three distinct parts, latest results from basic research on stable enzymes are explained and brought into context with possible industrial applications. Downstream processing technology as well as biocatalytic and biotechnological production processes from global players display the enormous potential of biocatalysts. Application of "extreme" reaction conditions (i.e. unconventional, such as high temperature, pressure, and pH value) - biocatalysts are normally used within a well defined process window - leads to novel synthetic effects. Both novel enzyme systems and the synthetic routes in which they can be applied are made accessible to the reader. In addition, the complementary innovative process technology under unconventional conditions is highlighted by latest examples from biotech industry.

Biocatalysis and Nanotechnology

Biocatalysis and Nanotechnology Book
Author : Peter Grunwald
Publisher : CRC Press
Release : 2017-10-25
ISBN : 1351767542
Language : En, Es, Fr & De

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Book Description :

Nanobiocatalysis has rapidly developed into a subarea of enzyme biotechnology. It combines the advances in nanotechnology that have generated nanoscale materials of different sizes, shapes, and physicochemical properties, and the excellent characteristics of biocatalysts into an innovative technology. This book provides an overview of the various relations between nanotechnology and biocatalysis. It discusses the fabrication and application of nanomaterials for the immobilization of enzymes used in the sustainable production of goods and chemicals. Nanosupports have several advantages compared with bulk solid materials because of their high surface area, which results in a significantly reduced mass transfer limitation and comparatively high enzyme loading. These characteristics are also of great use for applications in the fields of enzymatic biosensors, biofuel cells, bioelectronics, and photoelectrochemical analyte detection, where conductive nanomaterials improve the rate of electron transfer. The book also presents an overview of nanotoxicology and covers nanostructured enzyme catalysis in organic solvents and its potential application for biodiesel production, probing of enzymatic activity, and identification of enzyme functions of inorganic nanoparticles as enzyme mimics.

Multi scale Quantum Models for Biocatalysis

Multi scale Quantum Models for Biocatalysis Book
Author : Darrin M. York,Tai-Sung Lee
Publisher : Springer Science & Business Media
Release : 2009-05-30
ISBN : 1402099568
Language : En, Es, Fr & De

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Book Description :

“Multi-scale Quantum Models for Biocatalysis” explores various molecular modelling techniques and their applications in providing an understanding of the detailed mechanisms at play during biocatalysis in enzyme and ribozyme systems. These areas are reviewed by an international team of experts in theoretical, computational chemistry, and biophysics. This book presents detailed reviews concerning the development of various techniques, including ab initio molecular dynamics, density functional theory, combined QM/MM methods, solvation models, force field methods, and free-energy estimation techniques, as well as successful applications of multi-scale methods in the biocatalysis systems including several protein enzymes and ribozymes. This book is an excellent source of information for research professionals involved in computational chemistry and physics, material science, nanotechnology, rational drug design and molecular biology and for students exposed to these research areas.

Engineering Heterogeneous Biocatalysis

Engineering Heterogeneous Biocatalysis Book
Author : Tushar Navin Patel
Publisher : Unknown
Release : 2014
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Overall, this dissertation explores immobilization of enzymes to create heterogeneous biocatalysts. First, the effects of immobilization on enzyme structure, stability, and activity are shown for two different immobilization techniques: adsorption to a solid surface and periplasmic expression in E. coli cells. After characterization, engineering of the whole-cell biocatalysts for improved properties is presented. Finally, future directions for this work are discussed which would advance our understanding of heterogeneous biocatalysts, as well as enhance their utility.

Biocatalysis and Pharmaceuticals A Smart Tool for Sustainable Development

Biocatalysis and Pharmaceuticals  A Smart Tool for Sustainable Development Book
Author : Andres R Alcantara
Publisher : MDPI
Release : 2019-10-30
ISBN : 3039217089
Language : En, Es, Fr & De

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Book Description :

Biocatalysis, that is, the use of biological catalysts (enzymes, cells, etc.) for the preparation of highly valuable compounds is undergoing a great development, being considered an extremely sustainable approach to undertaking environmental demands. In this scenario, this book illustrates the versatility of applied biocatalysis for the preparation of drugs and other bioactive compounds through the presentation of different research articles and reviews, in which several authors describe the most recent developments in this appealing scientific area. By reading the excellent contributions gathered in this book, it is possible to have an updated idea about new advances and possibilities for a new exciting future.

Green Biocatalysis

Green Biocatalysis Book
Author : Ramesh N. Patel
Publisher : John Wiley & Sons
Release : 2016-05-12
ISBN : 1118822366
Language : En, Es, Fr & De

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Book Description :

Green Biocatalysis presents an exciting green technology that uses mild and safe processes with high regioselectivity and enantioselectivity. Bioprocesses are carried out under ambient temperature and atmospheric pressure in aqueous conditions that do not require any protection and deprotection steps to shorten the synthetic process, offering waste prevention and using renewable resources. Drawing on the knowledge of over 70 internationally renowned experts in the field of biotechnology, Green Biocatalysis discusses a variety of case studies with emphases on process R&D and scale-up of enzymatic processes to catalyze different types of reactions. Random and directed evolution under process conditions to generate novel highly stable and active enzymes is described at length. This book features: A comprehensive review of green bioprocesses and application of enzymes in preparation of key compounds for pharmaceutical, fine chemical, agrochemical, cosmetic, flavor, and fragrance industries using diverse enzymatic reactions Discussion of the development of efficient and stable novel biocatalysts under process conditions by random and directed evolution and their applications for the development of environmentally friendly, efficient, economical, and sustainable green processes to get desired products in high yields and enantiopurity The most recent technological advances in enzymatic and microbial transformations and cuttingedge topics such as directed evolution by gene shuffling and enzyme engineering to improve biocatalysts With over 3000 references and 800 figures, tables, equations, and drawings, Green Biocatalysis is an excellent resource for biochemists, organic chemists, medicinal chemists, chemical engineers, microbiologists, pharmaceutical chemists, and undergraduate and graduate students in the aforementioned disciplines.

Applied Bioengineering

Applied Bioengineering Book
Author : Toshiomi Yoshida,Sang Yup Lee,Jens Nielsen,Gregory Stephanopoulos
Publisher : John Wiley & Sons
Release : 2017-06-06
ISBN : 3527340750
Language : En, Es, Fr & De

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Book Description :

A comprehensive overview of the topic, highlighting ongoing research trends and future directions. Experts from Europe, Asia and the US cover five core areas of imminent importance to the food, feed, pharmaceutical and water treatment industries in terms of sustainable and innovative processing and production. In the field of enzyme engineering, they summarize historic developments and provide an overview of molecular enzyme engineering, while also discussing key principles of microbial process engineering, including chapters on process development and control. Further sections deal with animal and plant cell culture engineering. The final section of the book deals with environmental topics and highlights the application of bioengineering principles in waste treatment and the recovery of valuable resources. With its cutting-edge visions, extensive discussions and unique perspectives, this is a ready reference for biotechnologists, bioengineers, biotechnological institutes, and environmental chemists. Advanced Biotechnology Biotechnology is a broad, interdisciplinary field of science, combining biological sciences and relevant engineering disciplines, that is becoming increasingly important as it benefits the environment and society as a whole. Recent years have seen substantial advances in all areas of biotechnology, resulting in the emergence of brand new fields. To reflect this progress, Sang Yup Lee (KAIST, South Korea), Jens Nielsen (Chalmers University, Sweden), and Gregory Stephanopoulos (MIT, USA) have joined forces as the editors of a new Wiley-VCH book series. Advanced Biotechnology will cover all pertinent aspects of the field and each volume will be prepared by eminent scientists who are experts on the topic in question.