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From Pasteur To Post Genomic Era

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Neurosciences at the Postgenomic Era

Neurosciences at the Postgenomic Era Book
Author : Jacques Mallet
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3642555438
Language : En, Es, Fr & De

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Book Description :

In this new volume in the series Research and Perspectives in Neurosciences the authors have presented and discussed their findings in the fields of speech and language disorders, X-linked mental retardation, gene therapy in the CNS, memory and learning disorders and other fields.

Spirochete Biology The Post Genomic Era

Spirochete Biology  The Post Genomic Era Book
Author : Ben Adler
Publisher : Springer
Release : 2018-08-21
ISBN : 3319896385
Language : En, Es, Fr & De

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Book Description :

Spirochetes comprise a fascinating group of bacteria. Although diverse in terms of their habitat, ecology and infectivity for vertebrate and non-vertebrate hosts, they are often considered together because of their similar cellular morphologies. This volume brings together an international group of experts to provide essential insights into spirochete biology, with an emphasis on recent advances made possible by the availability of genome sequences. As such, it offers a valuable resource for microbiologists and other scientists with an interest in spirochete biology.

Metabolic Engineering in the Post Genomic Era

Metabolic Engineering in the Post Genomic Era Book
Author : Boris N. Kholodenko,Hans V. Westerhoff
Publisher : Garland Science
Release : 2004
ISBN : 9780954523220
Language : En, Es, Fr & De

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Book Description :

The Horizon Scientific Press titles focus on high-level microbiology and molecular biology topics. Written by internationally renowned and highly respected leaders in the field, titles in this series comprise of review manuals, practical manuals, and reference texts for research scientists, bioscience professionals and graduate students. Engineering living cells continues to pose immense challenges to the researcher. In fact many bioengineers have only just started to appreciate the full extent of the hierarchical control used by living systems: upon attempts to increase the activity of a "rate-limiting" step, the multiple feedbacks at the metabolic, signaling and genetic levels result in the rate limiting step shifting to elsewhere in that pathway or even to elsewhere in the whole organism. The advent of full-force genomics should enable preventing this response, however, it has been difficult for researchers to know where to turn for guidance. This book aims to help the reader understand and deal with the plasticity of living cell factories and to turn the plasticity into the desired rather than the adverse direction. The book brings together all the recent, most important breakthroughs in this exciting field: Internationally renowned key scientists have reviewed each topic in detail. In the Introduction, the editors give an overview of new approaches and spell out what the engineer and the industry may now really begin to aim for; they even adapt the definition of metabolic engineering to befit the post-genomics era. Other topics included are: the experimental approaches necessary to understand cellular regulation at all of its hierarchical levels, including proteomics [Chapter 2], metabolomics [Chapter 3] and fluxomics [Chapter 4]; new tools that help metabolic engineering [Chapters 5-7]; modeling of living cells, e.g. finding metabolic pathways [Chapter 8] and comparing the actual and predicted use of these in living organisms such as E. coli and Corynebacteria [Chapters 9, 10]; the optimization of cell factories as production organisms (e.g., use of whole cell models, silicon cells, and coordinate manipulation of multiple genes [Chapters 12-15]). A chapter on future perspectives directs further developments of the field in the near future. Metabolic Engineering in the Post Genomic Erais an essential reading for everyone with an interest in engineering living cells including: Metabolic egnineers, bioengineers, biotechnologists, molecular biologists, and pharmaceutical and biotechnology companies.

Molecular Vaccines against Pathogens in the Post Genomic Era

Molecular Vaccines against Pathogens in the Post Genomic Era Book
Author : Angel Alejandro Oñate,Alberto Moreno,Yanmin Wan
Publisher : Frontiers Media SA
Release : 2020-02-27
ISBN : 2889635139
Language : En, Es, Fr & De

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Book Description :

Download Molecular Vaccines against Pathogens in the Post Genomic Era book written by Angel Alejandro Oñate,Alberto Moreno,Yanmin Wan, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

From Pasteur to Post Genomic Era

From Pasteur to Post Genomic Era Book
Author : Ipek Kurtböke
Publisher : Academic Press
Release : 2020-05
ISBN : 9780128182727
Language : En, Es, Fr & De

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Book Description :

Since the discovery of the microscope microbiology has received significant attention since microorganisms played a significant role in the advancement as well as destruction of the mankind such as the black death. With the discovery of penicillin from a fungal culture beneficial role of microorganisms has been a major catalyst in the progress of biological sciences. Interestingly, there are fundamental aspects of microbiology that did not change since revelations of their identity dating back to the Pasteur era. On the other hand, molecular and biochemical advances have revealed further beneficial properties of the microorganisms in relation to the higher organisms and their functional existence. Microbiology teaching has its own pedagogy and focus again dating back to Pasteur days, however, to be able to skill future microbiologists, new delivery methods covering molecular advances and bioinformatics should be implemented. Microbiology Discipline-based teaching: From Pasteur to Post-Genomic Era: brings world experts together to highlight the importance of microbiology-discipline based teaching with its unique skills based approaches. Emphasizes both on traditional and discipline-based teaching with a focus on microbiology Combines pedagogy and the challenges faced in the post-genomic era Provides examples from various parts of the world including Pasteur Institute

Handbook of Molecular and Cellular Methods in Biology and Medicine Third Edition

Handbook of Molecular and Cellular Methods in Biology and Medicine  Third Edition Book
Author : Leland J. Cseke,Ara Kirakosyan,Peter B. Kaufman,Margaret V. Westfall
Publisher : CRC Press
Release : 2011-12-12
ISBN : 1420069381
Language : En, Es, Fr & De

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Book Description :

Several milestones in biology have been achieved since the first publication of the Handbook of Molecular and Cellular Methods in Biology and Medicine. This is true particularly with respect to genome-level sequencing of higher eukaryotes, the invention of DNA microarray technology, advances in bioinformatics, and the development of RNAi technology. Now in its third edition, this volume provides researchers with an updated tool kit that incorporates conventional as well as modern approaches to tackle biological and medicinal research in the post-genomics era. Significantly revised to address these recent changes, the editors have evaluated, revised, and sometimes replaced protocols with more efficient, more reliable, or simpler ones. The book has also been reorganized with section headings focusing on different biological levels connected to one another, taking into account the central dogma of biology (DNA → RNA → protein → metabolites). The book first explores traditional approaches and then moves to the modern "omics" approaches, including genomics, proteomics, and metabolomics. It also discusses the manipulation of biological systems (including RNAi) and macromolecular analyses, focusing on the use of microscopy. In each chapter, various notes and cautionary considerations are presented for potentially hazardous reagents. Filled with diagrams, tables, and figures to clarify methods, most chapters also contain Troubleshooting Guides indicating problems, possible causes, and solutions that may be incurred in carrying out the procedures. Researchers and scientists who master the techniques in this book are putting themselves at the cutting edge of biological and medicinal research.

From Plant Genomics to Plant Biotechnology

From Plant Genomics to Plant Biotechnology Book
Author : Palmiro Poltronieri,Natalija Burbulis,Corrado Fogher
Publisher : Elsevier
Release : 2013-08-31
ISBN : 1908818476
Language : En, Es, Fr & De

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Book Description :

With the appearance of methods for the sequencing of genomes and less expensive next generation sequencing methods, we face rapid advancements of the -omics technologies and plant biology studies: reverse and forward genetics, functional genomics, transcriptomics, proteomics, metabolomics, the movement at distance of effectors and structural biology. From plant genomics to plant biotechnology reviews the recent advancements in the post-genomic era, discussing how different varieties respond to abiotic and biotic stresses, understanding the epigenetic control and epigenetic memory, the roles of non-coding RNAs, applicative uses of RNA silencing and RNA interference in plant physiology and in experimental transgenics and plants modified to specific aims. In the forthcoming years these advancements will support the production of plant varieties better suited to resist biotic and abiotic stresses, for food and non-food applications. This book covers these issues, showing how such technologies are influencing the plant field in sectors such as the selection of plant varieties and plant breeding, selection of optimum agronomic traits, stress-resistant varieties, improvement of plant fitness, improving crop yield, and non-food applications in the knowledge based bio-economy. Discusses a broad range of applications: the examples originate from a variety of sectors (including in field studies, breeding, RNA regulation, pharmaceuticals and biotech) and a variety of scientific areas (such as bioinformatics, -omics sciences, epigenetics, and the agro-industry) Provides a unique perspective on work normally performed 'behind closed doors'. As such, it presents an opportunity for those within the field to learn from each other, and for those on the 'outside' to see how different groups have approached key problems Highlights the criteria used to compare and assess different approaches to solving problems. Shows the thinking process, practical limitations and any other considerations, aiding in the understanding of a deeper approach

Molecular Vaccines

Molecular Vaccines Book
Author : Matthias Giese
Publisher : Springer Science & Business Media
Release : 2013-11-08
ISBN : 3319009788
Language : En, Es, Fr & De

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Book Description :

This title discusses all aspects of non-infectious and non-cancer– so called NINC – vaccines. Hypertension, diabetes and allergy vaccine development are referred to as well as the use of adjuvants and nanotechnology in vaccine development. The way of novel vaccines from bench to preclinical to clinical studies and launch to the market under EMEA (European Medicines Agency) and FDA (Food and Drug Administration) guidelines are described in-depth. The book is therefore of interest for researchers and clinicians engaged in vaccine development and molecular vaccine application.

Index Medicus

Index Medicus Book
Author : Anonim
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Index Medicus book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Cellular and Molecular Biology of Filamentous Fungi

Cellular and Molecular Biology of Filamentous Fungi Book
Author : Katherine Borkovich,Daniel J. Ebbole
Publisher : American Society for Microbiology Press
Release : 2010-02-02
ISBN : 1555814735
Language : En, Es, Fr & De

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Book Description :

An ideal starting point for any research study of filamentous fungi. • Incorporates the latest findings from such disciplines as physiology, taxonomy, genomics, molecular biology and cell biology. • Begins with an historical perspective, cell morphology and taxonomy, and moves on to such topics as cell growth, development, metabolism, and pathogenesis. • Presents the full range of the fungal kingdom and covers important topics as saprophytes, pathogens and endophytes. • Serves as a recommended text for graduate and undergraduate students.

Textbook of Animal Biotechnology

Textbook of Animal Biotechnology Book
Author : B Singh
Publisher : The Energy and Resources Institute (TERI)
Release : 2005-01-01
ISBN : 817993327X
Language : En, Es, Fr & De

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Book Description :

Animal biotechnology is an integral component of agriculture. Supported with over 50 figures and more than 30 tables, this textbook is a must have for undergraduates and postgraduates of various agriculture and animal husbandry academia, teachers, professionals, and researchers in basic as well as applied animal sciences including biotechnology, nutrition, physiology and reproduction. The book covers various topics, including economically important livestock breeds, paradigm shifts in livestock production, biotechnology in animal nutrition and in livestock-assisted reproduction, and genomics and genetic engineering tools in livestock production and management.

Innovation in Vaccinology

Innovation in Vaccinology Book
Author : Selene Baschieri
Publisher : Springer Science & Business Media
Release : 2012-07-20
ISBN : 9400745435
Language : En, Es, Fr & De

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Book Description :

Prevention of infectious diseases by vaccination is one of the most significant achievements of modern medicine. During the 20th century, the average human life span in the developed world was about 70 years and it is expected to increase, with a significant portion of this increase directly attributed to vaccination. Since the first empiric vaccination trials, knowledge and technology have enormously evolved and new vaccination strategies are emerging on the market. Indeed, in spite of the great success, conventional vaccination strategies sometimes may result ineffective and, above all, may raise safety concerns. The aim of this book is to provide an overview of some of the technology platforms that have been realized or are currently under development to try to address unsolved and new issues in the field of vaccine development. Common denominator of all thematic areas described herein is the multidisciplinary teamwork. Most of the enabling technologies have been established by putting in the “melting pot” expertise in fields that, at first glance, may appear very far apart. I hope that this collection of articles will make the readers aware that vaccinology is rapidly taking a new direction, ceasing to be an empirical science.

Antiparasitic and Antibacterial Drug Discovery

Antiparasitic and Antibacterial Drug Discovery Book
Author : Paul M. Selzer
Publisher : John Wiley & Sons
Release : 2009-06-08
ISBN : 3527323279
Language : En, Es, Fr & De

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Book Description :

Mainly addressing parasitic diseases but also focusing on diseases caused by bacteria, this much-needed reference and handbook provides a unique insight into the approach adopted by commercial science towards infectious diseases, including the work of medicinal chemists. Many of the authors are scientists with hands-on experience of drug discovery units within the pharmaceutical industry. In addition, the text covers efforts towards drug development in infectious diseases from academic groups and non profit organizations.

RTD Info

RTD Info Book
Author : Anonim
Publisher : Unknown
Release : 2002-11
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download RTD Info book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Microbial Pathogenomics

Microbial Pathogenomics Book
Author : H. de Reuse,S. Bereswill
Publisher : Karger Medical and Scientific Publishers
Release : 2009-08-27
ISBN : 3805591934
Language : En, Es, Fr & De

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Book Description :

Microbial Pathogenomics' contains a unique collection of reviews demonstrating how genomics has revolutionized our understanding of virulence, host-adaptation strategies and the evolution of bacterial pathogens. Current technologies - computational tools and functional approaches to genome analysis - are carefully documented and clearly illustrated. These include visualization tools for genome comparison, databases, in silico metabolic reconstructions and function prediction as well as interactomics for the study of protein-protein interactions. The concepts of pan-genomics and reverse vaccinology are introduced as strategies when addressing the challenge presented by bacterial diversity in the prevention and treatment of infectious diseases. The authors explore individual bacterial pathogens and discuss the mechanisms that have contributed to their evolutionary success. Special cases of host adaptation, for example, are illustrated by Helicobacter pylori and 'Mycobacterium tuberculosis' which are human-specific and highly persistent; further bacteria discussed include 'Escherichia coli, Campylobacter, Pseudomonas, Legionella, Bartonella, Burkholderia' and 'Staphylococcus'. 'Microbial Pathogenomics' provides the reader with a global view of key aspects and future trends in bacterial pathogenomics and evaluates their impact on the understanding and treatment of infectious diseases. Well illustrated and accessible to both specialists and nonspecialists, it is recommended not only for researchers in microbiology, genomics and biotechnology, but also for lecturers and teachers.

Medicinal Plants

Medicinal Plants Book
Author : M. K. Rai,Geoffrey A. Cordell,Jose L. Martinez,Mariela Marinoff,Luca Rastrelli
Publisher : CRC Press
Release : 2012-07-03
ISBN : 1466507950
Language : En, Es, Fr & De

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Book Description :

This volume provides a contemporary overview of new strategies for traditional medicine development. It emphasizes the importance of cataloging ethnomedical information, determining the active principles, and examining the genetic diversity and range of actions of traditional medicines. It discusses the challenges of using traditional medicines for diseases where access to modern medicine is limited, and the research areas needed to improve quality, safety, and efficacy for enhancing healthcare. Affirming the importance of traditional medicines as an essential and integral component of healthcare systems, it explores the vast opportunities for their evidence-based development.

Computer Applications in Biotechnology 2004

Computer Applications in Biotechnology 2004 Book
Author : Marie-Noelle Pons,Jan Van Impe
Publisher : Elsevier
Release : 2005-08-16
ISBN : 9780080442518
Language : En, Es, Fr & De

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Book Description :

Download Computer Applications in Biotechnology 2004 book written by Marie-Noelle Pons,Jan Van Impe, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Carbohydrate Bioengineering

Carbohydrate Bioengineering Book
Author : Tuula T Teeri,B Svensson,H J Gilbert,T Feizi
Publisher : Royal Society of Chemistry
Release : 2007-10-31
ISBN : 1847550320
Language : En, Es, Fr & De

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Book Description :

Carbohydrate bioengineering is a rapidly expanding field with many applications in medicine and industry. Presenting state-of-the-art research, Carbohydrate Bioengineering: Interdisciplinary Approaches brings together international experts on many different aspects of this burgeoning topic. Coverage includes: the engineering of glycosidases for constructive purposes; structure-function studies and protein engineering of carbohydrate-active enzymes; chemo-enzymatic carbohydrate synthesis; and trends emerging from comprehensive work on genomes and glycomes. This timely publication will be welcomed by all those needing access to the latest research in the field, including practitioners in the medicinal, chemical, food and pharmaceutical areas.

Advances in Bioengineering Research and Application 2012 Edition

Advances in Bioengineering Research and Application  2012 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-12-26
ISBN : 1464990956
Language : En, Es, Fr & De

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Book Description :

Advances in Bioengineering Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Bioengineering. The editors have built Advances in Bioengineering Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Bioengineering in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Bioengineering Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Applied Biotechnology

Applied Biotechnology Book
Author : Sudhir U. Meshram,Gangadhar Bangadhar Shinde
Publisher : I. K. International Pvt Ltd
Release : 2009-01-01
ISBN : 9380026560
Language : En, Es, Fr & De

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Book Description :

This book vividly brings out the complexities, intricacies and constraints in developing and adopting appropriate sustainable technologies in the applied fields of Agriculture, Environment, Biomedical & Animal Genetic Engineering, Immunology etc. It covers Biosensors, Bioremediation, Biofertilizers, Fermentation, Immunization, DNA Transportation, Biopesticides, Sustainable strategies, Agriculture, Animal & Health Sectors etc. It will be of great use not only to teachers and students of Biotechnology and Life Sciences but also to farm scientists, extension managers, policy makers and administrators alike.