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Evidence Based Validation of Herbal Medicine

Evidence Based Validation of Herbal Medicine Book
Author : Pulok K. Mukherjee
Publisher : Elsevier
Release : 2015-02-17
ISBN : 0128009969
Language : En, Es, Fr & De

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Book Description :

Evidence-Based Validation of Herbal Medicines brings together current thinking and practice in the areas of characterization and validation of natural products. This book reviews all aspects of evaluation and development of medicines from plant sources, including their cultivation, collection, phytochemical and phyto-pharmacological evaluation, and therapeutic potential. Emphasis is placed on describing the full range of evidence-based analytical and bio-analytical techniques used to characterize natural products, including –omic technologies, phyto-chemical analysis, hyphenated techniques, and many more. Includes state-of-the-art methods for detecting, isolating, and performing structure elucidation by degradation and spectroscopic techniques Covers biosynthesis, synthesis, and biological activity related to natural products Consolidates information to save time and money in research Increases confidence levels in quality and validity of natural products

Evidence Based Validation of Traditional Medicines

Evidence Based Validation of Traditional Medicines Book
Author : Subhash C Mandal,Raja Chakraborty,Saikat Sen
Publisher : Springer
Release : 2021-02-10
ISBN : 9789811581267
Language : En, Es, Fr & De

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Book Description :

The demand for traditional medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements and herbal cosmetics etc. is increasing globally due to the growing recognition of these products as mainly non-toxic, having lesser side effects, better compatibility with physiological flora, and availability at affordable prices. In the last century, medical science has made incredible advances all over the globe. In spite of global reorganization and a very sound history of traditional uses, the promotion of traditional medicine faces a number of challenges around the globe, primarily in developed nations. Regulation and safety is the high concern for the promotion of traditional medicine. Quality issues and quality control, pharmacogivilane, scientific investigation and validation, intellectual property rights, and biopiracy are some key issues that restrain the advancement of traditional medicine around the globe. This book contains diverse and unique chapters, explaining in detail various subsections like phytomolecule, drug discovery and modern techniques, standardization and validation of traditional medicine, and medicinal plants, safety and regulatory issue of traditional medicine, pharmaceutical excipients from nature, plants for future. The contents of the book will be useful for the academicians, researchers and people working in the area of traditional medicine.

Evidence Based Validation of Herbal Medicine

Evidence Based Validation of Herbal Medicine Book
Author : Pulok K. Mukherjee
Publisher : Elsevier
Release : 2022-06-15
ISBN : 9780323855426
Language : En, Es, Fr & De

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Book Description :

Evidence-Based Validation of Herbal Medicines, second edition brings together current thinking and practice in the areas of characterization and validation of natural products. This book reviews all aspects of evaluation and development of medicines from plant sources, including their cultivation, collection, phytochemical and phyto-pharmacological evaluation, and therapeutic potential. Emphasis is placed on describing the full range of evidence-based analytical and bio-analytical techniques used to characterize natural products, including -omic technologies, phyto-chemical analysis, hyphenated techniques, and many more. This thoroughly updated new edition covers several aspects of evaluation and development of newer drugs from medicinal plants and evaluation of their therapeutic potential together with their evidence-based validation. It addresses the possible difficulties in the field of natural product research at large. It highlights various aspects of quality control parameters, safety evaluation and therapeutic efficacy. It focuses on better understanding hyphenated state-of-the-art technologies including NMR, IR, HPTLC, HPLC, UPLC, LC-MS and others. It contains the latest research from eminent scientists and researchers around the globe on several aspects of translational research on the evaluation of herbal medicine, and it serves as a useful bioprospecting tool for traditional-medicine-inspired drug discovery and development. Includes state-of-the-art methods for detecting, isolating, and performing structure elucidation by degradation and spectroscopic techniques Highlights the trends in validation and value addition of herbal medicine with different scientific approaches used in therapeutics Contains several all-new chapters on topics such as traditional-medicine-inspired drug development to treat emerging viral diseases, medicinal plants in antimicrobial resistance, TLC bio profiling, botanicals as medicinal foods, bioprospecting and bioassay-guided isolation of medicinal plants, immunomodulators from medicinal plants, and more

Quality Control and Evaluation of Herbal Drugs

Quality Control and Evaluation of Herbal Drugs Book
Author : Pulok K. Mukherjee
Publisher : Elsevier
Release : 2019-05-30
ISBN : 0128133988
Language : En, Es, Fr & De

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Book Description :

Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal medicine in therapeutics is on the rise in both developed and developing countries and this book facilitates the necessary development of quality standards for these medicines.This book elucidates on various challenges and opportunities for quality evaluation of herbal drugs with several integrated approaches including metabolomics, chemoprofiling, marker analysis, stability testing, good practices for manufacturing, clinical aspects, Ethnopharmacology and Ethnomedicine inspired drug development. Written by Prof. Pulok K Mukherjee, a leader in this field; the book highlights on various methods, techniques and approaches for evaluating the purity, quality, safety and efficacy of herbal drugs. Particular attention is paid to methods that assess these drugs’ activity, the compounds responsible and their underlying mechanisms of action. The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, and other Asian countries, as well as the regulatory profiles of the European Union and North America. This book will be useful in bio-prospecting of natural products and traditional medicine-inspired drug discovery and development. Provides new information on the research and development of natural remedies - essential reading on the study and use of natural resources for preventative or healing purposes Brings together current thinking and practices in quality control and standardization of herbal drugs highlighting several integrated approaches for metabolomics, chemo-profiling and marker analysis Aids in developing knowledge of various techniques including macroscopy, microscopy, HPTLC, HPLC, LC-MS/MS, GC-MS etc. with the development of integrated methods for evaluation of botanicals used in traditional medicine Assessment of herbal drugs through bio-analytical techniques, bioassay guided isolation, enzyme inhibition, pharmacological, microbiological, antiviral assays and safety related quality issues References global organizations, such as the WHO, USFDA, CDSCO, AYUSH, TCM and others to serve as a comprehensive document for enforcement agencies, NGOs and regulatory authorities

Evidence Based Validation of Traditional Medicines

Evidence Based Validation of Traditional Medicines Book
Author : Subhash C. Mandal
Publisher : Springer Nature
Release : 2020
ISBN : 9811581274
Language : En, Es, Fr & De

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Book Description :

Download Evidence Based Validation of Traditional Medicines book written by Subhash C. Mandal, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Herbal Drugs and Fingerprints

Herbal Drugs and Fingerprints Book
Author : Devi Datt Joshi
Publisher : Springer Science & Business Media
Release : 2012-11-02
ISBN : 8132208048
Language : En, Es, Fr & De

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Book Description :

Evidence based herbal drugs are on hi-acceptance day by day due to health friendly nature compared to synthetic drugs. The active ingredients in herbal drugs are different chemical classes, e.g. alkaloids, coumarins, flavonoids, glycosides, phenols, steroids, terpenes etc., are identified at molecular level using current analytical practices, which are unique characteristic, as finger, so known as fingerprints. The fingerprints are used for assessment of quality consistency and stability by visible observation and comparison of the standardized fingerprint pattern, have scientific potential to decipher the claims made on these drugs for authenticity and reliability of chemical constituents, with total traceability, which starts from the proper identification, season and area of collection, storage, their processing, stability during processing, and rationalizing the combinational in case of polyherbal drugs. These quality oriented documents have ample scientific logics so well accepted globally by regulatory authorities and industries, to determine intentional/ unintentional contamination, adulteration, pollutants, stability, quality, etc. parameters. Based on geo-climatic factors, a same plant species has different pharmacological properties due to different ingredients; such regional and morphological variations are identified by fingerprints, at the time of collection of the medicinal herb. The chromatographic (TLC, HPTLC, HPLC, GC,) and spectral (UV-Vis., FTIR, MNR, MS, LC-MS, GC-MS etc.) techniques have world-wide strong scientific approval as validated methods to generate the fingerprints of different chemical classes of active ingredients of herbal drugs. Presently there is a need for a book having all the fingerprinting techniques for herbal drugs at a place with theory, case studies and art to discover patentable forms. The present book is a mile stone in the subject, to be utilized by Scientists, Medical Doctors, Technicians, Industrialists, Researchers, and Students both in PG and UG levels.

Natural Medicines

Natural Medicines Book
Author : Dilip Ghosh,Pulok K. Mukherjee
Publisher : CRC Press
Release : 2019-07-18
ISBN : 1351741357
Language : En, Es, Fr & De

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Book Description :

Globally, natural medicine has been considered as an important alternative to modern allopathic medicine. Although natural medicines are popular in society, only limited medicinal herbs have been scientifically evaluated for their potential in medical treatment. This book connects various aspects of the complex journey from traditional medicine to modern medicine. It provides information on topics including global regulations and regulatory hurdles, diverse nutritional challenges and potential health benefits, novel food innovations especially seed-to-clinic approaches, and future trends. FEATURES • Provides information on sustainable use of natural products in the development of new drugs and clinically validated herbal remedies • Discusses issues on evaluation and clinical aspects of herbal medicine, promotion and development, safety evaluation, metabolite profiling, biomarker analysis, formulation, and stability testing • Describes traditional uses of natural medicine through identification, isolation and structural characterization of their active components • Elucidates mechanisms of biological action, adverse effects and identification of their molecular targets of natural medicine • Multidisciplinary appeal including chemistry, pharmacology, pharmacognosy and cell and molecular biology, as well as integration with clinical medicine This book serves as an essential guide for individuals researching natural medicines, and industry employees in areas including drug development, pharmacology, natural products chemistry, clinical efficacy, ethnopharmacology, pharmacognosy, phytotherapy, phyto-technology and herbal science.

Nutrition and Disease

Nutrition and Disease Book
Author : Kenneth Lundstrom
Publisher : Cambridge Scholars Publishing
Release : 2020-02-24
ISBN : 1527547531
Language : En, Es, Fr & De

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Book Description :

Nutrition is an essential part of life. It affects our health and can be applied in the prevention and treatment of disease. Substantial interventions in dietary intake and lifestyle changes have been demonstrated to cause significant decrease in disease risk in in the general population and also in patients suffering from various diseases. Traditional plant-based diets and medicines have received much attention as an alternative to modern science-based drugs, while recent technology development in bioinformatics, genomics, and proteomics has provided a better understanding of plant-based drugs, improved quality assurance and allowed the acceleration of clinical trials to bridge the gap with Western medicine. Moreover, research in nutrigenomics and epigenomics has further enhanced the knowledge of the association between nutrition and disease. The book deals with the concerns of the future well-being of our planet, the health of the global human population related to the worldwide obesity epidemic, the issues related to sustainable food production, and the need for a switch to a healthier, more plant-based diet.

Herbs Spices and Medicinal Plants

Herbs  Spices and Medicinal Plants Book
Author : Mohammad B. Hossain,Nigel P. Brunton,Dilip K. Rai
Publisher : John Wiley & Sons
Release : 2020-08-17
ISBN : 1119036631
Language : En, Es, Fr & De

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Book Description :

The latest research on the health benefits and optimal processing technologies of herbs and spices This book provides a comprehensive overview of the health benefits, analytical techniques used, and effects of processing upon the physicochemical properties of herbs and spices. Presented in three parts, it opens with a section on the technological and health benefits of herbs and spices. The second part reviews the effect of classical and novel processing techniques on the properties of herbs/spices. The third section examines extraction techniques and analytical methodologies used for herbs and spices. Filled with contributions from experts in academia and industry, Herbs, Spices and Medicinal Plants: Processing, Health Benefits and Safety offers chapters covering thermal and non-thermal processing of herbs and spices, recent developments in high-quality drying of herbs and spices, conventional and novel techniques for extracting bioactive compounds from herbs and spices, and approaches to analytical techniques. It also examines purification and isolation techniques for enriching bioactive phytochemicals, medicinal properties of herbs and spices, synergy in whole-plant medicine, potential applications of polyphenols from herbs and spices in dairy products, biotic and abiotic safety concerns, and adverse human health effects and regulation of metal contaminants in terrestrial plant-derived food and phytopharmaceuticals. Covers the emerging health benefits of herbs and spices, including their use as anti-diabetics, anti-inflammatories, and anti-oxidants Reviews the effect of classical and novel processing techniques on the properties of herbs and spices Features informed perspectives from noted academics and professionals in the industry Part of Wiley's new IFST Advances in Food Science series Herbs, Spices and Medicinal Plants is an important book for companies, research institutions, and universities active in the areas of food processing and the agri-food environment. It will appeal to food scientists and engineers, environmentalists, and food regulatory agencies.

Herbal Medicine in Andrology

Herbal Medicine in Andrology Book
Author : Ralf Henkel,Ashok Agarwal
Publisher : Academic Press
Release : 2020-11-20
ISBN : 0128155663
Language : En, Es, Fr & De

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Book Description :

Herbal Medicine in Andrology: An Evidence-Based Update provides a comprehensive overview of ethnomedical approaches in andrology, including ethnopharmacology of plant extracts and relevant bioactive compounds. It highlights information on the availability of medicinal plants and the legal and procedural processes involved in developing a marketable product. This reference helps clinicians and scientists develop an understanding on how herbal medicine can be used to treat andrological patients in practice. Only a limited number of journal articles are available on this topic, making this reference a valuable source of information for a large audience, including urologists, andrologists, gynecologists, reproductive endocrinologists and basic scientists. Provides essential evidence-based information about herbal medicine Offers an ethnopharmacological background on bioactive compounds in certain plant extracts Educates the basic scientist and clinician on the use of herbal medicines in andrology Provides an update to recent advances on herbal medicine in andrology from world experts

Herbal Medicine in India

Herbal Medicine in India Book
Author : Saikat Sen,Raja Chakraborty
Publisher : Springer Nature
Release : 2019-09-10
ISBN : 9811372489
Language : En, Es, Fr & De

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Book Description :

This book highlights the medical importance of and increasing global interest in herbal medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements, herbal cosmetics, etc. It also addresses various issues that are hampering the advancement of Indian herbal medicine around the globe; these include quality concerns and quality control, pharmacovigilance, scientific investigation and validation, IPR and biopiracy, and the challenge that various indigenous systems of medicine are at risk of being lost. The book also explores the role of traditional medicine in providing new functional leads and modern approaches that can offer elegant strategies for facilitating the drug discovery process. The book also provides in-depth information on various traditional medicinal systems in India and discusses their medical importance. India has a very long history of safely using many herbal drugs. Folk medicine is also a key source of medical knowledge and plays a vital role in maintaining health in rural and remote areas. Despite its importance, this form of medicine largely remains under-investigated. Out of all the traditional medicinal systems used worldwide, Indian traditional medicine holds a unique position, as it has continued to deliver healthcare throughout the Asian subcontinent since ancient times. In addition, traditional medicine has been used to derive advanced techniques and investigate many modern drugs. Given the scope of its coverage, the book offers a valuable resource for scientists and researchers exploring traditional and herbal medicine, as well as graduate students in courses on traditional medicine, herbal medicine and pharmacy.

Ethnopharmacology

Ethnopharmacology Book
Author : Michael Heinrich,Anna K. Jäger
Publisher : John Wiley & Sons
Release : 2015-08-25
ISBN : 111893072X
Language : En, Es, Fr & De

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Book Description :

Ethnopharmacology is one of the world’s fastest-growing scientific disciplines encompassing a diverse range of subjects. It links natural sciences research on medicinal, aromatic and toxic plants with socio-cultural studies and has often been associated with the development of new drugs. The Editors of Ethnopharmacology have assembled an international team of renowned contributors to provide a critical synthesis of the substantial body of new knowledge and evidence on the subject that has emerged over the past decade. Divided into three parts, the book begins with an overview of the subject including a brief history, ethnopharmacological methods, the role of intellectual property protection, key analytical approaches, the role of ethnopharmacology in primary/secondary education and links to biodiversity and ecological research. Part two looks at ethnopharmacological contributions to modern therapeutics across a range of conditions including CNS disorders, cancer, bone and joint health and parasitic diseases. The final part is devoted to regional perspectives covering all continents, providing a state-of-the –art assessment of the status of ethnopharmacological research globally. A comprehensive, critical synthesis of the latest developments in ethnopharmacology. Includes a section devoted to ethnopharmacological contributions to modern therapeutics across a range of conditions. Contributions are from leading international experts in the field. This timely book will prove invaluable for researchers and students across a range of subjects including ethnopharmacology, ethnobotany, medicinal plant research and natural products research. Ethnopharmacology- A Reader is part of the ULLA Series in Pharmaceutical Sciences www.ullapharmsci.org

Anticancer Plants Natural Products and Biotechnological Implements

Anticancer Plants  Natural Products and Biotechnological Implements Book
Author : Mohd Sayeed Akhtar,Mallappa Kumara Swamy
Publisher : Springer
Release : 2018-07-02
ISBN : 981108064X
Language : En, Es, Fr & De

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Book Description :

This volume provides summarized scientific evidence of the different classes of plant-derived phytocompounds, their sources, chemical structures, anticancer properties, mechanisms of action, methods of extraction, and their applications in cancer therapy. It also discusses endophyte-derived compounds as chemopreventives to treat various cancer types. In addition, it provides detailed information on the enhanced production of therapeutically valuable anticancer metabolites using biotechnological interventions such as plant cell and tissue culture approaches, including in vitro-, hairy root- and cell-suspension culture; and metabolic engineering of biosynthetic pathways. Anticancer Plants: Natural Products and Biotechnological Implements – Volume 2” explores the natural bioactive compounds isolated from plants as well as fungal endophytes, their chemistry, and preventive effects to reduce the risk of cancer. Moreover, it highlights the genomics/proteomics approaches and biotechnological implementations. Providing solutions to deal with the challenges involved in cancer therapy, the book benefits a wide range of readers including academics, students, and industrial experts working in the area of natural products, medicinal plant chemistry, pharmacology, and biotechnology.

Drug Selectivity

Drug Selectivity Book
Author : Norbert Handler,Helmut Buschmann,Raimund Mannhold,Jörg Holenz
Publisher : John Wiley & Sons
Release : 2018-02-05
ISBN : 3527335382
Language : En, Es, Fr & De

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Book Description :

The book provides a current overview and comprehensive compilation for medicinal chemists that discusses the effects of aiming for multiple targets on the entire drug development process. The result is a broad survey of current and future strategies for drug selectivity in medicinal chemistry with theoretical but also practical aspects. Different strategies are presented and evaluated, such as various design approaches, merged multiple ligands, discovery technologies and a broad range of successful examples of unselective drugs taken from all major disease areas. With its wide-ranging view of an emerging new paradigm in drug development, this handbook is of prime importance for every medicinal and pharmaceutical chemist.

Sustainable Agriculture Reviews 43

Sustainable Agriculture Reviews 43 Book
Author : Ankit Saneja,Amulya K. Panda,Eric Lichtfouse
Publisher : Springer Nature
Release : 2020-05-05
ISBN : 3030418383
Language : En, Es, Fr & De

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Book Description :

This edited book comprises of eight chapters dealing on various aspects of pharmaceutical technology for delivery of natural products. Book chapters deal with the solubility and bioavailability enhancement technologies for natural products. Emphasis has also been given on the significance of delivery strategies for improving the therapeutic efficacy of paclitaxel, galantamine and tea constituents.

New Approaches for the Discovery of Pharmacologically Active Natural Compounds

New Approaches for the Discovery of Pharmacologically Active Natural Compounds Book
Author : José L. Medina-Franco
Publisher : MDPI
Release : 2019-07-01
ISBN : 3039211048
Language : En, Es, Fr & De

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Book Description :

A major source of active compounds, natural products from different sources supply a large variety of molecules that have been approved for clinical use or used as the starting points of optimization programs. This book features nine papers (eight full articles and one review paper) written by more than 45 scientists from around the world. These papers illustrate the development and application of a broad range of computational and experimental techniques applied to natural product research. On behalf of the contributors to the book, our hope is that the research presented here contributes to advancements in the field, and encourages multidisciplinary teams, young scientists, and students to further advance in the discovery of pharmacologically-active natural compounds

Nanotechnology

Nanotechnology Book
Author : Bhaskar Mazumder,Subhabrata Ray,Paulami Pal,Yashwant Pathak
Publisher : CRC Press
Release : 2019-03-18
ISBN : 1351111868
Language : En, Es, Fr & De

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Book Description :

Today we find the applications of nanotechnology in all spheres of life. Nanotechnology: Therapeutic, Nutraceutical and Cosmetic Advances discusses recent advances in the field, particularly with therapeutics, nutraceuticals and cosmetic sciences. Therapeutics is an area which has perhaps benefitted the most, although nanoscience and technology have quietly entered the realms of food science and are playing pivotal roles in the efficient utilization of nutraceuticals. Finally, even before therapeutics came cosmetics and companies started marketing unique products embedding the beneficial and advanced properties enabled by the use of nanostructures. This book highlights trends and applications of this wonderful new technology.

A History of Health Fitness Implications for Policy Today

A History of Health   Fitness  Implications for Policy Today Book
Author : Roy J. Shephard
Publisher : Springer
Release : 2017-09-18
ISBN : 3319650971
Language : En, Es, Fr & De

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Book Description :

This book provides a unique and succinct account of the history of health and fitness, responding to the growing recognition of physicians, policy makers and the general public that exercise is the most potent form of medicine available to humankind. Individual chapters present information extending from the earliest reaches of human history to the present day, arranged in the form of 30 thematic essays covering topics from the supposed idyll of the hunter-gatherer lifestyle and its posited health benefits to the evolution of health professionals and the possible contribution of the Olympic movement to health and fitness in our current society. Learning objectives are set for each topic, and although technical language is avoided as far as possible, a thorough glossary explains any specialized terms that are introduced in each chapter. The critical thinking of the reader is stimulated by a range of questions arising from the text context, and each chapter concludes with a brief discussion of some of the more important implications for public policies on health and fitness today and into the future. The material will be of particular interest to graduate and undergraduate students in public health, health promotion, health policy, kinesiology, physical education, but will be of interest also to many studying medicine, history and sociology.

Novel Drug Delivery Systems for Phytoconstituents

Novel Drug Delivery Systems for Phytoconstituents Book
Author : Madhu Gupta,Durgesh Nandini Chauhan,Vikas Sharma,Nagendra Singh Chauhan
Publisher : CRC Press
Release : 2019-07-23
ISBN : 1351057618
Language : En, Es, Fr & De

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Book Description :

Novel Drug Delivery Systems for Phytoconstituents discusses general principles of drug targeting, construction material and technological concerns of different phytoconstituent in delivery systems. It focuses on the development of novel herbal formulations and summarizes their method of preparation, type of active ingredients, route of administration, biological activity and their applications. It dicusses therapeutic activities of plant derived chemicals, their limitations in clinical applications and novel drug delivery solutions to overcome them to provide better therapeutic effects with controlled and targeted drug delivery. Focus on drug delivery of phytomolecules Act as bridge between natural product scientist and clinical doctors Discusses mechanism of poor bioavailability of herbal molecules Increases awareness towards phytochemical efficacy Summarizes efficient novel delivery systems-based formulations. It extensively covers the applications of novel drug delivery systems including polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid capsules, liposomes, phytosomes, microsphere, transferosomes, and ethosomes. Some chapters are especially focused on anticancer phytodrugs, silymarin, andrographolide, berberine, and curcumin delivery with special emphasis on their application.

Herbal Medicines

Herbal Medicines Book
Author : Giacinto Bagetta,Marco Cosentino,Marie Tiziana Corasaniti,Shinobu Sakurada
Publisher : CRC Press
Release : 2016-04-19
ISBN : 1439837694
Language : En, Es, Fr & De

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Book Description :

The deregulation of dietary supplements and natural products marketing by the FDA has widened the natural products market in Europe and worldwide. While the discussion about the validity of the plant approach to nutrition and diseases treatment continues, the explosion of the use of whatever is considered "natural" has generated concern about effec