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Evidence Based Validation Of Herbal Medicine

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Evidence Based Validation of Herbal Medicine

Evidence Based Validation of Herbal Medicine Book
Author : Pulok K. Mukherjee
Publisher : Elsevier
Release : 2022-07-12
ISBN : 0323984568
Language : En, Es, Fr & De

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Book Description :

Evidence-Based Validation of Herbal Medicines: Translational Research on Botanicals brings together current thinking and practice in the characterization and validation of natural products. The book describes different approaches and techniques for evaluating the quality, safety and efficacy of herbal medicine, particularly methods to assess their activity and understand compounds responsible and their probable underlying mechanisms of action. This book brings together the views, expertise and experiences of scientific experts in the field of medicinal plant research, hence it will be useful for researcher who want to know more about the natural lead with their validation and also useful to exploit traditional medicines. Includes state-of-the-art methods for detecting, isolating and performing structure elucidation by degradation and spectroscopic techniques Highlights the trends in validation and value addition of herbal medicine with different scientific approaches used in therapeutics Contains several all-new chapters on topics such as traditional-medicine-inspired drug development to treat emerging viral diseases, medicinal plants in antimicrobial resistance, TLC bio profiling, botanicals as medicinal foods, bioprospecting and bioassay-guided isolation of medicinal plants, immunomodulators from medicinal plants, and more

Evidence Based Validation of Traditional Medicines

Evidence Based Validation of Traditional Medicines Book
Author : Subhash C. Mandal,Raja Chakraborty,Saikat Sen
Publisher : Springer Nature
Release : 2021-01-18
ISBN : 9811581274
Language : En, Es, Fr & De

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Book Description :

The demand for traditional medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements and herbal cosmetics etc. is increasing globally due to the growing recognition of these products as mainly non-toxic, having lesser side effects, better compatibility with physiological flora, and availability at affordable prices. In the last century, medical science has made incredible advances all over the globe. In spite of global reorganization and a very sound history of traditional uses, the promotion of traditional medicine faces a number of challenges around the globe, primarily in developed nations. Regulation and safety is the high concern for the promotion of traditional medicine. Quality issues and quality control, pharmacogivilane, scientific investigation and validation, intellectual property rights, and biopiracy are some key issues that restrain the advancement of traditional medicine around the globe. This book contains diverse and unique chapters, explaining in detail various subsections like phytomolecule, drug discovery and modern techniques, standardization and validation of traditional medicine, and medicinal plants, safety and regulatory issue of traditional medicine, pharmaceutical excipients from nature, plants for future. The contents of the book will be useful for the academicians, researchers and people working in the area of traditional medicine.

Quality Control and Evaluation of Herbal Drugs

Quality Control and Evaluation of Herbal Drugs Book
Author : Pulok K. Mukherjee
Publisher : Elsevier
Release : 2019-05-30
ISBN : 0128133988
Language : En, Es, Fr & De

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Book Description :

Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal medicine in therapeutics is on the rise in both developed and developing countries and this book facilitates the necessary development of quality standards for these medicines.This book elucidates on various challenges and opportunities for quality evaluation of herbal drugs with several integrated approaches including metabolomics, chemoprofiling, marker analysis, stability testing, good practices for manufacturing, clinical aspects, Ethnopharmacology and Ethnomedicine inspired drug development. Written by Prof. Pulok K Mukherjee, a leader in this field; the book highlights on various methods, techniques and approaches for evaluating the purity, quality, safety and efficacy of herbal drugs. Particular attention is paid to methods that assess these drugs’ activity, the compounds responsible and their underlying mechanisms of action. The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, and other Asian countries, as well as the regulatory profiles of the European Union and North America. This book will be useful in bio-prospecting of natural products and traditional medicine-inspired drug discovery and development. Provides new information on the research and development of natural remedies - essential reading on the study and use of natural resources for preventative or healing purposes Brings together current thinking and practices in quality control and standardization of herbal drugs highlighting several integrated approaches for metabolomics, chemo-profiling and marker analysis Aids in developing knowledge of various techniques including macroscopy, microscopy, HPTLC, HPLC, LC-MS/MS, GC-MS etc. with the development of integrated methods for evaluation of botanicals used in traditional medicine Assessment of herbal drugs through bio-analytical techniques, bioassay guided isolation, enzyme inhibition, pharmacological, microbiological, antiviral assays and safety related quality issues References global organizations, such as the WHO, USFDA, CDSCO, AYUSH, TCM and others to serve as a comprehensive document for enforcement agencies, NGOs and regulatory authorities

From Ayurveda to Chinese Medicine

From Ayurveda to Chinese Medicine Book
Author : Ping-Chung Leung
Publisher : World Scientific Publishing Company
Release : 2017-04-12
ISBN : 9789813200333
Language : En, Es, Fr & De

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Book Description :

This unique book presents the differences and similarities of the oldest system of health care. All ancient medicine has strong philosophical background and management varieties related to treatment activities. Ayurveda is one such branch of medicine that is strongly linked to Yoga and traditional Chinese medicine including activities related to Martial Arts and Acupuncture. This book successfully merges Ayurveda with Chinese medicine thereby enhancing the understanding of the two systems.

Scientific Validation of Herbal Medicine

Scientific Validation of Herbal Medicine Book
Author : Daniel Mowrey
Publisher : McGraw-Hill Education
Release : 1998-11-01
ISBN : 9780879835347
Language : En, Es, Fr & De

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Book Description :

Book cover - In this book, Dr Mowrey provides the answers on why herbal medicine is effective - possibly more effective in treatment than pharmaceutical drugs and medications.

Herbal Medicine in India

Herbal Medicine in India Book
Author : Saikat Sen,Raja Chakraborty
Publisher : Springer Nature
Release : 2019-09-10
ISBN : 9811372489
Language : En, Es, Fr & De

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Book Description :

This book highlights the medical importance of and increasing global interest in herbal medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements, herbal cosmetics, etc. It also addresses various issues that are hampering the advancement of Indian herbal medicine around the globe; these include quality concerns and quality control, pharmacovigilance, scientific investigation and validation, IPR and biopiracy, and the challenge that various indigenous systems of medicine are at risk of being lost. The book also explores the role of traditional medicine in providing new functional leads and modern approaches that can offer elegant strategies for facilitating the drug discovery process. The book also provides in-depth information on various traditional medicinal systems in India and discusses their medical importance. India has a very long history of safely using many herbal drugs. Folk medicine is also a key source of medical knowledge and plays a vital role in maintaining health in rural and remote areas. Despite its importance, this form of medicine largely remains under-investigated. Out of all the traditional medicinal systems used worldwide, Indian traditional medicine holds a unique position, as it has continued to deliver healthcare throughout the Asian subcontinent since ancient times. In addition, traditional medicine has been used to derive advanced techniques and investigate many modern drugs. Given the scope of its coverage, the book offers a valuable resource for scientists and researchers exploring traditional and herbal medicine, as well as graduate students in courses on traditional medicine, herbal medicine and pharmacy.

Traditional and Complementary Medicine

Traditional and Complementary Medicine Book
Author : Cengiz Mordeniz
Publisher : BoD – Books on Demand
Release : 2019-12-11
ISBN : 1789841836
Language : En, Es, Fr & De

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Book Description :

Modern medicine has reached a point where the patient is not treated as a biopsychosocial-spiritual being but rather is seen as a virtual identity consisting of laboratory findings and images. More focus is placed on relieving the symptoms instead of curing the disease. Mostly, patients are turned into lifetime medication-dependent individuals. New medicines are needed to overcome the side effects, complications, resistance, and intolerance caused by pharmacological and interventional therapies. In hopes of drug-free and painless alternative treatments with fewer complications, there has been a trend to revisit traditional methods that have been dismissed by modern medicine. Traditional medicine has to be reevaluated with modern scientific methods to complement and integrate with evidence-based modern medicine.

Herbal Drugs and Fingerprints

Herbal Drugs and Fingerprints Book
Author : Devi Datt Joshi
Publisher : Springer Science & Business Media
Release : 2012-11-02
ISBN : 8132208048
Language : En, Es, Fr & De

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Book Description :

Evidence based herbal drugs are on hi-acceptance day by day due to health friendly nature compared to synthetic drugs. The active ingredients in herbal drugs are different chemical classes, e.g. alkaloids, coumarins, flavonoids, glycosides, phenols, steroids, terpenes etc., are identified at molecular level using current analytical practices, which are unique characteristic, as finger, so known as fingerprints. The fingerprints are used for assessment of quality consistency and stability by visible observation and comparison of the standardized fingerprint pattern, have scientific potential to decipher the claims made on these drugs for authenticity and reliability of chemical constituents, with total traceability, which starts from the proper identification, season and area of collection, storage, their processing, stability during processing, and rationalizing the combinational in case of polyherbal drugs. These quality oriented documents have ample scientific logics so well accepted globally by regulatory authorities and industries, to determine intentional/ unintentional contamination, adulteration, pollutants, stability, quality, etc. parameters. Based on geo-climatic factors, a same plant species has different pharmacological properties due to different ingredients; such regional and morphological variations are identified by fingerprints, at the time of collection of the medicinal herb. The chromatographic (TLC, HPTLC, HPLC, GC,) and spectral (UV-Vis., FTIR, MNR, MS, LC-MS, GC-MS etc.) techniques have world-wide strong scientific approval as validated methods to generate the fingerprints of different chemical classes of active ingredients of herbal drugs. Presently there is a need for a book having all the fingerprinting techniques for herbal drugs at a place with theory, case studies and art to discover patentable forms. The present book is a mile stone in the subject, to be utilized by Scientists, Medical Doctors, Technicians, Industrialists, Researchers, and Students both in PG and UG levels.

Natural Medicines

Natural Medicines Book
Author : Dilip Ghosh,Pulok K. Mukherjee
Publisher : CRC Press
Release : 2019-07-18
ISBN : 1351741349
Language : En, Es, Fr & De

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Book Description :

Globally, natural medicine has been considered as an important alternative to modern allopathic medicine. Although natural medicines are popular in society, only limited medicinal herbs have been scientifically evaluated for their potential in medical treatment. This book connects various aspects of the complex journey from traditional medicine to modern medicine. It provides information on topics including global regulations and regulatory hurdles, diverse nutritional challenges and potential health benefits, novel food innovations especially seed-to-clinic approaches, and future trends. FEATURES • Provides information on sustainable use of natural products in the development of new drugs and clinically validated herbal remedies • Discusses issues on evaluation and clinical aspects of herbal medicine, promotion and development, safety evaluation, metabolite profiling, biomarker analysis, formulation, and stability testing • Describes traditional uses of natural medicine through identification, isolation and structural characterization of their active components • Elucidates mechanisms of biological action, adverse effects and identification of their molecular targets of natural medicine • Multidisciplinary appeal including chemistry, pharmacology, pharmacognosy and cell and molecular biology, as well as integration with clinical medicine This book serves as an essential guide for individuals researching natural medicines, and industry employees in areas including drug development, pharmacology, natural products chemistry, clinical efficacy, ethnopharmacology, pharmacognosy, phytotherapy, phyto-technology and herbal science.

WHO Guidelines on Safety Monitoring of Herbal Medicines in Pharmacovigilance Systems

WHO Guidelines on Safety Monitoring of Herbal Medicines in Pharmacovigilance Systems Book
Author : World Health Organization
Publisher : Unknown
Release : 2004-01-01
ISBN : 9789241592215
Language : En, Es, Fr & De

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Book Description :

Safety is a fundamental principle in the privision of herbal medicines and herbal products for health care and a critical component of quality control. These guidelines provide practical technical guidance for monitoring the safety of herbal medicines with pharmacovigilance systems.

Medicinal Plants for Holistic Health and Well Being

Medicinal Plants for Holistic Health and Well Being Book
Author : Namrita Lall
Publisher : Academic Press
Release : 2017-09-27
ISBN : 0128124768
Language : En, Es, Fr & De

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Book Description :

Medicinal Plants for Holistic Health and Well-Being discusses, in depth, the use of South African plants to treat a variety of ailments, including tuberculosis, cancer, periodontal diseases, acne, postmacular hypomelanosis, and more. Plants were selected on the basis of their traditional use, and the book details the scientific evidence that supports their pharmacological and therapeutic potential to safely and effectively treat each disease. Thus, this book is a valuable resource for all researchers, students and professors involved in advancing global medicinal plant research. Many plants found in South Africa are also found in other parts of the world. Each chapter highlights plants from other worldwide locations so that scientists can study which plants belong to the same family, and how similar qualities can be used to treat a specific disease. Uses traditional medicine as an efficient means to identify and further investigate South African and similar plants used as lead compounds in modern drug discovery Includes a number of chapters dedicated to using medicinal plants to treat various skin disorders, which is not covered often in other books on medicinal plants Organized by specific diseases, with vital evidence-based data related to the bioactivity, pharmacological potential, chemical structure and safety information

Evaluation of Herbal Medicinal Products

Evaluation of Herbal Medicinal Products Book
Author : Peter J. Houghton,Pulok K. Mukherjee
Publisher : Unknown
Release : 2009-01-01
ISBN : 9780853697510
Language : En, Es, Fr & De

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Book Description :

"This book presents a structural approach to the evaluation of herbal medicinal products for quality, safety and efficacy. There has been an enormous growth in the market for herbal medicinal products in the last twenty five years. However the rediscovery of natural substances with therapeutic potential has raised questions of quality, safety and efficacy on the part of the consumer and also from health professionals. This book brings together current thinking and practice in these areas highlighting current research. In the light of increasing legislation to enforce better standards for these products and the demand by legislators and the public for assurance of safe and effective use, this book seeks to provide a state-of-the-art review, which informs and guides those who seek to promote their use. This book also gives an overview of the place of ethno pharmacology in the development of herbal medicinal products and discusses good agricultural and collection practices, marker analysis and stability testing which contribute to assessment of good quality of these materials." -- Publisher description.

Medicinal Plants

Medicinal Plants Book
Author : M. K. Rai,Geoffrey A. Cordell,Jose L. Martinez,Mariela Marinoff,Luca Rastrelli
Publisher : CRC Press
Release : 2012-07-03
ISBN : 1466507950
Language : En, Es, Fr & De

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Book Description :

This volume provides a contemporary overview of new strategies for traditional medicine development. It emphasizes the importance of cataloging ethnomedical information, determining the active principles, and examining the genetic diversity and range of actions of traditional medicines. It discusses the challenges of using traditional medicines for diseases where access to modern medicine is limited, and the research areas needed to improve quality, safety, and efficacy for enhancing healthcare. Affirming the importance of traditional medicines as an essential and integral component of healthcare systems, it explores the vast opportunities for their evidence-based development.

Herbal Medicine

Herbal Medicine Book
Author : Iris F. F. Benzie,Sissi Wachtel-Galor
Publisher : CRC Press
Release : 2011-03-28
ISBN : 1439807167
Language : En, Es, Fr & De

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Book Description :

The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef

American Herbal Products Association s Botanical Safety Handbook Second Edition

American Herbal Products Association   s Botanical Safety Handbook  Second Edition Book
Author : Zoë Gardner,Michael McGuffin
Publisher : CRC Press
Release : 2013-03-15
ISBN : 1466516941
Language : En, Es, Fr & De

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Book Description :

Access to accurate, evidence-based, and clinically relevant information is essential to anyone who uses or recommends herbal products. With input from some of the most respected experts in herbal and integrative medicine, this completely revised edition of the American Herbal Products Association’s Botanical Safety Handbook reviews both traditional knowledge and contemporary research on herbs to provide an authoritative resource on botanical safety. The book covers more than 500 species of herbs and provides a holistic understanding of safety through data compiled from clinical trials, pharmacological and toxicological studies, medical case reports, and historical texts. For each species, a brief safety summary is provided for quick reference, along with a detailed review of the literature. Easily understood classification systems are used to indicate the safety of each listed species and the potential for the species to interact with drugs. Enhancements to the Second Edition include: Classification of each herb with both a safety rating and a drug interaction rating More references listed for each individual herb, vetted for accuracy Specific information on adverse events reported in clinical trials or case reports Safety-related pharmacology and pharmacokinetics of each herb, including drug interactions Additional information on the use of herbs by pregnant or lactating women Toxicological studies and data on toxic compounds Representing the core of the botanical trade and comprising the finest growers, processors, manufacturers, and marketers of herbal products, the mission of the AHPA is to promote the responsible commerce of herbal products. The American Herbal Products Association Botanical Safety Handbook, Second Edition ensures that this vision is attained. The book will be a valuable reference for product manufacturers, healthcare practitioners, regulatory agencies, researchers, and consumers of herbal products.

WHO Monographs on Selected Medicinal Plants

WHO Monographs on Selected Medicinal Plants Book
Author : World Health Organization
Publisher : World Health Organization
Release : 1999
ISBN : 9789241545372
Language : En, Es, Fr & De

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Book Description :

This is the second volume in a series of monographs which are intended to promote information exchange and international harmonised standards for the quality control and use of herbal medicines. It contains scientific information on 30 selected plants, and each entry includes a pharmacopoeial summary for quality assurance purposes, information on its clinical application and sections on contraindications, pharmacology, safety issues, and dosage forms. It provides two cumulative indexes with entries in alphabetical order by plant name and according to the plant material of interest.

Evidence based Herbal Medicine

Evidence based Herbal Medicine Book
Author : Michael Rotblatt,Irwin Ziment
Publisher : Unknown
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

A handbook of practical, objective, and clinically oriented information on the use of herbalism in health care. Potentially useful herbal medicines are differentiated from the many popular herbs of dubious value A report card format allows quick reading and easy access to relevant information Herbs are graded, with grades determined by usefulness, effectiveness, availability, and safety Handbook size-can be carried in lab coat Analyses-based on controlled studies, or meta-analyses or systematic reviews of the primary literature Sections of each report card include: Uses; Pharmacology; Clinical Trials; Adverse Effects; Preparations and Dose; Contraindications, Interactions, and Warnings; Conclusion and Recommendations; References An appendix lists and reviews other herbal medicine information resources Nonherbal dietary supplements also are addressed in a separate section.

Network Pharmacology

Network Pharmacology Book
Author : Shao Li
Publisher : Springer Nature
Release : 2021-09-29
ISBN : 9811607532
Language : En, Es, Fr & De

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Book Description :

This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.

Ethnopharmacology and Biodiversity of Medicinal Plants

Ethnopharmacology and Biodiversity of Medicinal Plants Book
Author : Jayanta Kumar Patra,Gitishree Das,Sanjeet Kumar,Hrudayanath Thatoi
Publisher : CRC Press
Release : 2019-08-05
ISBN : 0429675372
Language : En, Es, Fr & De

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Book Description :

Ethnopharmacology and Biodiversity of Medicinal Plants provides a multitude of contemporary views on the diversity of medicinal plants, discussing both their traditional uses and therapeutic claims. This book emphasizes the importance of cataloging ethnomedical information as well as examining and preserving the diversity of traditional medicines. It also discusses the challenges present with limited access to modern medicine and the ways in which research can be conducted to enhance these modern practices. The book also explores the conservation procedures for endangered plant species and discusses their relevance to ethnopharmacology. Each chapter of this book relays the research of experts in the field who conducted research in diverse landscapes of India, providing a detailed account of the basic and applied approaches of ethnobotany and ethnopharmacology. The book reviews multiple processes pertaining to medicinal plants, such as collecting the traditional therapeutic values and validation methods. It also explores developments in the field such as the diversity and medicinal potential of unexplored plant species and applications in drug formulation to fight against anti-microbial resistance (AMR).