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Eukaryotic Transcription Factors

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A Handbook of Transcription Factors

A Handbook of Transcription Factors Book
Author : Timothy R. Hughes
Publisher : Springer Science & Business Media
Release : 2011-05-10
ISBN : 904819069X
Language : En, Es, Fr & De

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Book Description :

Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes. In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution. This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.

Eukaryotic Transcription Factors

Eukaryotic Transcription Factors Book
Author : David Latchman,David S. Latchman
Publisher : Academic Press
Release : 2010-07-28
ISBN : 9780080561035
Language : En, Es, Fr & De

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Book Description :

Transcription, or the process by which DNA produces RNA, is a central aspect of gene expression. Transcription factors regulate transcription during development and in disease states. As such, it is critical for researchers to gain a good understanding of the relationship between the structure of various families of transcription factors and their function, as well as roles in human disease. Since publication of the Fourth Edition, there have been major advances, notably in the areas of chromatin remodeling and genome-scale analyses. This complete update includes all new coverage of the latest developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events. Potential of transcription factors as therapeutic targets in human disease Importance of histone modifications Use of genome-based sequence analysis and high-throughput methods Applications of the chromatin immunoprecipitation (ChIP) assay Transcriptional elongation Regulation by post-translational modifications Regulatory networks and bioinformatics

Protein Dimerization and Oligomerization in Biology

Protein Dimerization and Oligomerization in Biology Book
Author : Jacqueline M. Matthews
Publisher : Springer Science & Business Media
Release : 2012-09-04
ISBN : 1461432294
Language : En, Es, Fr & De

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Book Description :

This volume has a strong focus on homo-oligomerization, which is surprisingly common. However, protein function is so often linked to both homo- and hetero-oligomerization and many heterologous interactions likely evolved from homologous interaction, so this volume also covers many aspects of hetero-oligomerization.

Principles of Biology

Principles of Biology Book
Author : Lisa Bartee,Walter Shiner,Catherine Creech
Publisher : Unknown
Release : 2017
ISBN : 9781636350417
Language : En, Es, Fr & De

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Book Description :

The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research.

Biology for AP Courses

Biology for AP    Courses Book
Author : Julianne Zedalis,John Eggebrecht
Publisher : Unknown
Release : 2017-10-16
ISBN : 9781947172401
Language : En, Es, Fr & De

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Book Description :

Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.

Cells Molecules and Mechanisms

Cells  Molecules and Mechanisms Book
Author : E.V. Wong
Publisher : Axolotl Academic Publishing
Release : 2009
ISBN : 0985226110
Language : En, Es, Fr & De

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Book Description :

Download Cells Molecules and Mechanisms book written by E.V. Wong, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Transcription Factors in Eukaryotes

Transcription Factors in Eukaryotes Book
Author : Athanasios Papavassiliou
Publisher : International Thomson Publishing Services
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Transcription Factors in Eukaryotes book written by Athanasios Papavassiliou, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Mechanisms of Transcription

Mechanisms of Transcription Book
Author : Fritz Eckstein,David M.J. Lilley
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3642606911
Language : En, Es, Fr & De

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Book Description :

Mechanisms of Transcription presents a unique perspective on the fundamental processes of transcription. A collection of distinguished authors draws together the underlying mechanisms involved in the process of transcription. This includes RNA polymerase function and its interaction with promoter sequences, and the structures of the various components on the transcriptional machinery. Both prokaryotic and eukaryotic systems, NMR and crystallographic structures of a number of important eukaryotic transcription factors are discussed, as well as the role of chromatin structure.

Gene Regulation in Eukaryotes

Gene Regulation in Eukaryotes Book
Author : Edgar Wingender
Publisher : Wiley-Blackwell
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

A much-needed guide through the overwhelming amount of literature in the field. Comprehensive and detailed, this book combines background information with the most recentinsights. It introduces current concepts, emphasizing the transcriptional control of genetic information. Moreover, it links data on the structure of regulatory proteins with basic cellular processes. Both advanced students and experts will find answers to such intriguing questions as: - How are programs of specific gene repertoires activated and controlled? - Which genes drive and control morphogenesis? - Which genes govern tissue-specific tasks? - How do hormones control gene expression in coordinating the activities of different tissues? An abundant number of clearly presented glossary terms facilitates understanding of the biological background. Speacial feature: over 2200 (!) literature references.

Molecular Biology of the Cell

Molecular Biology of the Cell Book
Author : Bruce Alberts
Publisher : Unknown
Release : 2004
ISBN : 9780815332183
Language : En, Es, Fr & De

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Book Description :

Download Molecular Biology of the Cell book written by Bruce Alberts, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Cell Biology

Cell Biology Book
Author : Stephen R. Bolsover,Jeremy S. Hyams,Elizabeth A. Shephard,Hugh A. White,Claudia G. Wiedemann
Publisher : John Wiley & Sons
Release : 2004-02-15
ISBN : 0471461598
Language : En, Es, Fr & De

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Book Description :

This text tells the story of cells as the unit of life in a colorful and student-friendly manner, taking an "essentials only" approach. By using the successful model of previously published Short Courses, this text succeeds in conveying the key points without overburdening readers with secondary information. The authors (all active researchers and educators) skillfully present concepts by illustrating them with clear diagrams and examples from current research. Special boxed sections focus on the importance of cell biology in medicine and industry today. This text is a completely revised, reorganized, and enhanced revision of From Genes to Cells.

Cell Biology by the Numbers

Cell Biology by the Numbers Book
Author : Ron Milo,Rob Phillips
Publisher : Garland Science
Release : 2015-12-07
ISBN : 1317230698
Language : En, Es, Fr & De

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Book Description :

A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid

Transcription Factors

Transcription Factors Book
Author : Joseph Locker
Publisher : Garland Science
Release : 2012-10-12
ISBN : 1135323631
Language : En, Es, Fr & De

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Book Description :

Transcription factors are important in regulating gene expression, and their analysis is of paramount interest to molecular biologists studying this area. This book looks at the basic machinery of the cell involved in transcription in eukaryotes and factors that control transcription in eukaryotic cells. It examines the regulatory systems that modulate gene expression in all cells,a s well as the more specialized systems that regulate localized gene expression throughout the mammalian organism. Transcription Factors updates classical knowledge with recent advances to provide a full and comprehensive coverage of the field for postgraduates and researchers in molecular biology involved in the study of gene regulation.

Eukaryotic Gene Regulation

Eukaryotic Gene Regulation Book
Author : Gerald M. Kolodny
Publisher : CRC Press
Release : 2018-01-18
ISBN : 1351088831
Language : En, Es, Fr & De

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Book Description :

The cause of cancer and its many manifestations is at present unknown. Since many of its manifestations, including is control of cell division, appear to represent abnormal patterns of gene expression, studies of the regulation of gene expression nwill provide important insights in the understanding and treatment of cancer. This volume attempts to present some of the recent work on regulation of gene expression in eukaryotic cells.

Untranslated Gene Regions and Other Non coding Elements

Untranslated Gene Regions and Other Non coding Elements Book
Author : Lucy W. Barrett,Sue Fletcher,Steve D. Wilton
Publisher : Springer Science & Business Media
Release : 2013-06-26
ISBN : 3034806795
Language : En, Es, Fr & De

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Book Description :

There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5’ and 3’ untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.​

Concepts of Biology

Concepts of Biology Book
Author : Samantha Fowler,Rebecca Roush,James Wise
Publisher : Unknown
Release : 2018-01-07
ISBN : 9789888407453
Language : En, Es, Fr & De

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Book Description :

Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.

Transcriptional and Post transcriptional Regulation

Transcriptional and Post transcriptional Regulation Book
Author : Ghedira Kais
Publisher : BoD – Books on Demand
Release : 2018-10-10
ISBN : 1789237912
Language : En, Es, Fr & De

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Book Description :

This book focuses on the transcriptional and post-transcriptional gene regulations and presents a detailed portrait of many novel aspects related to highlighting the importance of key TFs in some vital biological processes, the role of certain TFs to control some infectious diseases, the role of non-coding RNAs in controlling mRNA expression, the involvement of these non-coding RNAs in diseases, and the interplay between TFs and microRNAs as key players for gene expression regulation giving a complete picture of how genes are regulated at the cellular level. The editor embarked upon this writing project entitled "Transcriptional and Post-transcriptional Regulation" to make pertinent contributions accessible to the scientific community. Hopefully, a large audience will enjoy reading and benefit from the chapters of this book.

Macromolecular Protein Complexes II Structure and Function

Macromolecular Protein Complexes II  Structure and Function Book
Author : J. Robin Harris,Jon Marles-Wright
Publisher : Springer Nature
Release : 2020-01-14
ISBN : 3030281515
Language : En, Es, Fr & De

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Book Description :

This book follows on from Volume 83 in the SCBI series (“Macromolecular Protein Complexes”), and addresses several important topics (such as the Proteasome, Anaphase Promoting Complex, Ribosome and Apoptosome) that were not previously included, together with a number of additional exciting topics in this rapidly expanding field of study. Although the first SCBI Protein Complex book focused on soluble protein complexes, the second (Vol. 87)addressed Membrane Complexes, and the third (Vol. 88) put the spotlight on Viral Protein and Nucleoprotein Complexes, a number of membrane, virus and even fibrillar protein complexes have been be considered for inclusion in the present book. A further book is also under preparation that follows the same pattern, in an attempt to provide a thorough coverage of the subject. Chapter 9 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Introduction to Basics of Pharmacology and Toxicology

Introduction to Basics of Pharmacology and Toxicology Book
Author : Gerard Marshall Raj,Ramasamy Raveendran
Publisher : Springer Nature
Release : 2019-11-16
ISBN : 9813297794
Language : En, Es, Fr & De

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Book Description :

This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureates in pharmacology and their significant discoveries. It then examines the general pharmacological principles - pharmacokinetics and pharmacodynamics, with in-depth information on drug transporters and interactions. In the remaining chapters, the book covers a definitive collection of topics containing essential information on the basic principles of pharmacology and how they are employed for the treatment of diseases. Readers will learn about special topics in pharmacology that are hard to find elsewhere, including issues related to environmental toxicology and the latest information on drug poisoning and treatment, analytical toxicology, toxicovigilance, and the use of molecular biology techniques in pharmacology. The book offers a valuable resource for researchers in the fields of pharmacology and toxicology, as well as students pursuing a degree in or with an interest in pharmacology.