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Epigenetics And Reproductive Health

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Epigenetics and Reproductive Health

Epigenetics and Reproductive Health Book
Author : Anonim
Publisher : Academic Press
Release : 2020-09-12
ISBN : 0128197544
Language : En, Es, Fr & De

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Book Description :

Epigenetics and Reproductive Health, a new volume in the Translational Epigenetics series, provides a thorough overview and discussion of epigenetics in reproduction and implications for reproductive medicine. Twenty international researchers discuss epigenetic mechanisms operating during the formation of male and female gametes, fertilization and subsequent embryo and placental development, particularly in mammals and transgenerational epigenetic inheritance. This volume also addresses aberrant epigenetic changes influencing male and female infertility, pregnancy related disorders, and those potentially linked to therapeutic manipulations and assisted reproductive technologies. Emphasis is placed on identifying biomarkers for early detection of aberrant epigenetic mechanisms. Later chapters examine the possibility of correcting these epigenetic dysfunctions, as well as current challenges and next steps in research, enabling new translational discoveries and efforts towards developing therapeutics. Thoroughly examines the influence of aberrant epigenetics during gametogenesis and embryogenesis, affecting parents, gametes and embryos, offspring and future generations Explores health outcomes for reproductive senescence, endocrine disruption, testicular cancer, prostrate cancer, breast cancer, ovarian, cancer, endometrial cancer and cervical cancers Features chapter contributions from international researchers in the field

Bisphenols and Male Reproductive Health

Bisphenols and Male Reproductive Health Book
Author : Arcangelo Barbonetti,Nicola Bernabò,Settimio D’Andrea,David H. Volle
Publisher : Frontiers Media SA
Release : 2020-12-10
ISBN : 2889662039
Language : En, Es, Fr & De

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Book Description :

Download Bisphenols and Male Reproductive Health book written by Arcangelo Barbonetti,Nicola Bernabò,Settimio D’Andrea,David H. Volle, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Genetic and Epigenetic Aspects of Assisted Reproductive Technologies

Genetic and Epigenetic Aspects of Assisted Reproductive Technologies Book
Author : Anonim
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Genetic and Epigenetic Aspects of Assisted Reproductive Technologies book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Epigenetics and Human Reproduction

Epigenetics and Human Reproduction Book
Author : Sophie Rousseaux,Saadi Khochbin
Publisher : Springer Science & Business Media
Release : 2010-11-03
ISBN : 9783642147739
Language : En, Es, Fr & De

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Book Description :

Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the ‘Epigenetics and Human Health’ series discusses the role of epigenetics in human reproduction

Male Reproductive Health

Male Reproductive Health Book
Author : Wei Wu,Francesco Ziglioli,Umberto Maestroni
Publisher : BoD – Books on Demand
Release : 2020-03-04
ISBN : 1789856477
Language : En, Es, Fr & De

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Book Description :

Male reproductive health is an important area affecting men's overall health and well-being. Infertility is a worldwide problem that affects approximately 15% of married couples. Half of these cases can be traced to male partners. Infertile men are at an elevated risk of cancer development later in life, primarily genitourinary malignancies such as testicular and prostate cancer. This book will focus on male reproductive health, from the aspects of semen quality, male infertility, testicular cancer, and prostate cancer, and their detection, diagnosis, treatment, and prevention.

Animal Models and Human Reproduction

Animal Models and Human Reproduction Book
Author : Heide Schatten,Gheorghe M. Constantinescu
Publisher : John Wiley & Sons
Release : 2017-01-12
ISBN : 1118881427
Language : En, Es, Fr & De

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Book Description :

Our knowledge of reproductive biology has increased enormously in recent years on cellular, molecular, and genetic levels, leading to significant breakthroughs that have directly benefitted in vitro fertilization (IVF) and other assisted reproductive technologies (ART) in humans and animal systems. Animal Models and Human Reproduction presents a comprehensive reference that reflects the latest scientific research being done in human reproductive biology utilizing domestic animal models. Chapters on canine, equine, cow, pig, frog, and mouse models of reproduction reflect frontier research in placental biology, ovarian function and fertility, non-coding RNAs in gametogenesis, oocyte and embryo metabolism, fertilization, cryopreservation, signal transduction pathways, chromatin dynamics, epigenetics, reproductive aging, and inflammation. Chapters on non-human primate models also highlight recent advancements into such issues as human in vitro fertilization (IVF) and assisted reproductive technologies (ART). This book offers animal scientists, reproductive biology scientists, clinicians and practitioners, invaluable insights into a wide range of issues at the forefront of human reproductive health.

Reproductive Medicine for Clinical Practice

Reproductive Medicine for Clinical Practice Book
Author : Joseph G. Schenker,John J. Sciarra,Liselotte Mettler,Andrea R. Genazzani,Martin Birkhaeuser
Publisher : Springer
Release : 2018-09-29
ISBN : 3319780093
Language : En, Es, Fr & De

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Book Description :

This first volume of the series of the International Academy of Human Reproduction focuses on new aspects of reproductive medicine, from the professional responsibility model of ethics to the areas of high clinical involvement in human reproduction, such as endometriosis, polycystic ovary, family planning and post-coital contraception. The book discusses fertility and assisted reproductive techniques in the context of genetics and epigenetics as well as psychosomatic and longevity aspects. In addition, it presents new technologies and therapeutic strategies to improve IVF results and prevent ovarian hyperstimulation syndrome, as well the new challenges and the future of imaging in reproduction. Menopause and the effects of estrogens on atero-prevention, mood, and more generally the reproductive hormones impact on dementia and healthy aging are also covered. Further, it includes a section devoted to innovative aspects of gynecological surgery, discussing the treatments of vaginal aplasia, reproductive microsurgery and technological breakthroughs in pelvic organ prolapse surgery. Last, but not least, it examines the syndromic aspects of preterm birth. This volume is a useful and comprehensive tool for gynecologists, obstetricians, endocrinologists and all specialists who deal with women’s reproductive health.

Weighing the Future

Weighing the Future Book
Author : Natali Valdez
Publisher : Unknown
Release : 2021-12-08
ISBN : 9780520380141
Language : En, Es, Fr & De

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Book Description :

Epigenetics is the study of heritable changes in gene expression and has been heralded as one of the most promising new fields of scientific inquiry. Current large-scale pregnancy studies draw on epigenetics to connect pregnant women's behavioral choices, like diet and exercise, to future health risks for unborn babies. As the first ethnography of its kind, Weighing the Future examines the sociopolitical implications of ongoing pregnancy trials in the United States and the United Kingdom, illuminating how processes of scientific knowledge production are linked to capitalism, surveillance, and environmental reproduction. The environments we imagine to shape our genes, bodies, and future health are tied to race, gender, and structures of inequality. This groundbreaking book makes the case that science, and how we translate it, is a reproductive project that requires feminist vigilance. Instead of fixating on a future at risk, this book brings attention to the present at stake.

Epigenetics and Human Reproduction

Epigenetics and Human Reproduction Book
Author : Sophie Rousseaux,Saadi Khochbin
Publisher : Springer
Release : 2010-11-05
ISBN : 9783642147722
Language : En, Es, Fr & De

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Book Description :

Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the ‘Epigenetics and Human Health’ series discusses the role of epigenetics in human reproduction

Environmental Impacts on Reproductive Health and Fertility

Environmental Impacts on Reproductive Health and Fertility Book
Author : Tracey J. Woodruff,Sarah J. Janssen,Louis J. Guillette, Jr,Linda C. Giudice
Publisher : Cambridge University Press
Release : 2010-01-28
ISBN : 1139484842
Language : En, Es, Fr & De

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Book Description :

Many reproductive and developmental health problems are caused by exposure to chemicals that are widely dispersed in our environment. These problems include infertility, miscarriage, poor pregnancy outcomes, abnormal fetal development, early puberty, endometriosis, and diseases and cancers of reproductive organs. The compelling nature of the collective science has resulted in recognition of a new field of environmental reproductive health. Focusing on exposures to environmental contaminants, particularly during critical periods in development and their potential effects on all aspects of future reproductive life-course, this book provides the first comprehensive source of information bringing together the arguments that are spread out among various scientific disciplines in environmental health, clinical and public health fields. It provides a review of the science in key areas of the relationship between environmental contaminants and reproductive health outcomes, and recommendations on efforts toward prevention in clinical care and public policy.

Handbook of Fertility

Handbook of Fertility Book
Author : Ronald Ross Watson
Publisher : Academic Press
Release : 2015-04-27
ISBN : 0128009934
Language : En, Es, Fr & De

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Book Description :

Handbook of Fertility: Nutrition, Diet, Lifestyle and Reproductive Health focuses on the ways in which food, dietary supplements, and toxic agents, including alcohol and nicotine affect the reproductive health of both women and men. Researchers in nutrition, diet, epidemiology, and endocrinology will find this comprehensive resource invaluable in their long-term goal of understanding and improving reproductive health. This book brings together a broad range of experts researching the different aspects of foods and dietary supplements that promote or detract from reproductive health. Section One contains several overview chapters on fertility, how it is assessed, and how it can be affected by different metabolic states, nutritional habits, dietary supplements, the action of antioxidants, and lifestyle choices. Sections Two and Three consider how male and female fertility are affected by obesity, metabolic syndrome, hormonal imbalance, and even bariatric surgery. Section Four explores the ways diet, nutrition, and lifestyle support or retard the success of in vitro fertilization, while Section Five explores how alcohol and other drugs of abuse lower fertility in both women and men. Explores how alcohol, nicotine, and other drugs of abuse disrupt and impair reproductive health Reviews studies of common conditions such as obesity and metabolic syndrome and their effect on fertility and reproductive health Investigates the components of foods and dietary supplements, in particular oxidative stress and antioxidants Presents the nutritional effects of foods and dietary supplements and their benefits and risks relating to reproductive health

Epigenetics and Human Reproduction

Epigenetics and Human Reproduction Book
Author : Sophie Rousseaux,Saadi Khochbin
Publisher : Springer
Release : 2011-07-23
ISBN : 9783642147746
Language : En, Es, Fr & De

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Book Description :

Epigenetics is a rapidly expanding field in medical and biological research which concerns heritable traits that are not attributable to changes in the DNA sequence. Epigenetic mechanisms play key roles in many biological processes, and it has become clear that their disruption can gives rise to diverse pathologies in humans. Edited by preeminent experts, Sophie Rousseaux and Saadi Khochbin, this volume in the ‘Epigenetics and Human Health’ series discusses the role of epigenetics in human reproduction

Encyclopedia of Reproduction

Encyclopedia of Reproduction Book
Author : Anonim
Publisher : Academic Press
Release : 2018-06-29
ISBN : 0128151455
Language : En, Es, Fr & De

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Book Description :

Encyclopedia of Reproduction, Second Edition comprehensively reviews biology and abnormalities, also covering the most common diseases in humans, such as prostate and breast cancer, as well as normal developmental biology, including embryogenesis, gestation, birth and puberty. Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers, from advanced undergraduate students, to research professionals. Chapters also explore the latest advances in cloning, stem cells, endocrinology, clinical reproductive medicine and genomics. As reproductive health is a fundamental component of an individual’s overall health status and a central determinant of quality of life, this book provides the most extensive and authoritative reference within the field. Provides a one-stop shop for information on reproduction that is not available elsewhere Includes extensive coverage of the full range of topics, from basic, to clinical considerations, including evolutionary advances in molecular, cellular, developmental and clinical sciences Includes multimedia and interactive teaching tools, such as downloadable PowerPoint slides, video content and interactive elements, such as the Virtual Microscope

Epigenetics in Human Disease

Epigenetics in Human Disease Book
Author : Trygve O. Tollefsbol
Publisher : Academic Press
Release : 2012
ISBN : 0123884152
Language : En, Es, Fr & De

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Book Description :

Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike. Comprehensive coverage of fundamental and emergent science and clinical usage Side-by-side coverage of the basis of epigenetic diseases and their treatments Evaluation of recent epigenetic clinical breakthroughs

Proceedings of 2nd International Congress on Epigenetics Chromatin 2017

Proceedings of 2nd International Congress on Epigenetics   Chromatin 2017 Book
Author : ConferenceSeries
Publisher : ConferenceSeries
Release : 2021-09-22
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

November 06-08, 2017 Frankfurt, Germany Key Topics : Epigenetics, Epigenomics, Immunogenetics, Translational Epigenetics, Neurodevelopmental Disorders, Bioinformatics Development in Epigenetics, Epigenetics and Environmental Origins of Cancer, Epigenetic Diseases – Clinical Applications, Pharmacogenomics & Personalized Medicine, Genetic Disorders, Current Case studies/ Discussions: Epigenetics, Cancer Epigenetics, Epigenetics Inheritance, Epigenetic Regulation, Epigenetics Mechanism, Epigenetics Psychology, Epigenetics Factors, Epigenetics Therapy, Clinical Epigenetics, Epigenetics Markers, Epigenetics Methylation, Epigenetics Silencing, Epigenetics Alteration, Neuronal Epigenetics, Epigenetics and Nutrition, Reproductive Epigenetics, Animal Epigenetics, Plant Epigenetics, Medical Epigenetics,

The Zero Trimester

The Zero Trimester Book
Author : Miranda Waggoner
Publisher : Univ of California Press
Release : 2017-09-12
ISBN : 0520288068
Language : En, Es, Fr & De

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Book Description :

-A healthy pregnancy is now defined well before pregnancy even begins. Public health messages promote pre-pregnancy health and health care by encouraging reproductive-age women to think of themselves as mothers before they think of themselves as women. This happens despite little evidence that such an approach improves maternal and child health. This book examines the dramatic shift in ideas about reproductive risk and birth outcomes over the last several decades, unearthing how these ideas intersect with the politics of women's health and motherhood at the beginning of the twenty-first century.---Provided by publisher.

Transgenerational and Epigenetic Effects of Developmental Exposure to Atrazine on Medaka Oryzias Latipes

Transgenerational and Epigenetic Effects of Developmental Exposure to Atrazine on Medaka  Oryzias Latipes  Book
Author : Jacob Alexander Cleary
Publisher : Unknown
Release : 2018
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

"Exposure to environmental chemicals can cause epigenetic transgenerational inheritance of altered phenotypes. Chemicals such as the plasticizer bisphenol-A (BPA), the fungicidal vinclozolin, and the oral contraceptive component 17a-ethinylestradiol (EE2) induce epigenetic changes in various species. Each of these chemicals is an environmentally pervasive endocrine disrupting compound, as is the case with the abundantly used herbicide atrazine, whose endocrine disrupting mechanisms still remain unclear. Atrazine (ATZ) is presently one of the most abundantly used herbicides in the United States, and a common contaminant of natural water bodies and drinking waters in high-use areas. ATZ belongs to the triazine herbicides which specifically target photosynthetic tissues, yet ATZ can affect animal health. Fish exposed to ATZ and EE2 display dysregulation of reproductive processes, which include alterations to the hypothalamic-pituitary-gonadal (HPG) axis pathways. However, the potential for ATZ-induced transgenerational inheritance of reproductive dysfunction has not been investigated in fish. The transgenerational reproductive consequences of ATZ exposure have been explored in rats, but fish are among the species at greatest risk from ATZ exposure, therefore, I chose a model species to represent this environmentally relevant scenario. In the present study I analyzed the effects of ATZ and EE2 exposures during early development on transgenerational reproductive dysregulation in Japanese medaka (Oryzias latipes). F0 medaka were exposed to ATZ, EE2, and a solvent during the first twelve days of development with no exposure over the subsequent three generations. These early developmental exposures overlap with the critical windows of embryonic germ cell development, gonadogenesis, and sex determination when gonadal DNA methylation is being reprogrammed. Exposed males and females of the F0 treatment lineages were bred to produce the F1 generation, the F1 offspring were bred to produce the F2 generation, and the F2 offspring were bred to produce the F3 generation. Neither ATZ nor EE2 altered sperm parameters, gonadosomatic, or hepatosomatic indices in the treated F0 generation. However, the hepatosomatic index was reduced in F2 females derived from F0 fish treated with either ATZ or EE2. Hepatosomatic and gonadosomatic indices are ratios of liver and gonad weights to the total weight of the fish, which are cursory metrics for evaluating energetic and reproductive health. The fecundity of F0 and F2 fish was unaffected by exposure to ATZ or EE2; however, the fertilization rate was decreased among the F2 fish derived from the low ATZ and low EE2 treated F0 generation. Moreover, there were significant transgenerational differences in the expression of reproductive regulatory genes and genes required for DNA methylation. Genomic methylation patterns are catalyzed by DNA methyltransferase enzymes (dnmts) that regulate the heritable transcriptional activity of specific regions of DNA essential to development. Present results suggest that early life exposure to ATZ and EE2 cause no significant effects in the immediate generation, but that future generations of fish are at greater risk of reproductive dysfunction."--Abstract from author supplied metadata.

Human Reproductive and Prenatal Genetics

Human Reproductive and Prenatal Genetics Book
Author : Peter C. K. Leung,Jie Qiao
Publisher : Academic Press
Release : 2018-08-28
ISBN : 0128135719
Language : En, Es, Fr & De

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Book Description :

Human Reproductive and Prenatal Genetics presents the latest material from a detailed molecular, cellular and translational perspective. Considering its timeliness and potential international impact, this all-inclusive and authoritative work is ideal for researchers, students, and clinicians worldwide. Currently, there are no comprehensive books covering the field of human reproductive and prenatal genetics. As such, this book aims to be among the largest and most useful references available. Features chapter contributions from leading international scientists and clinicians Provides in-depth coverage of key topics in human reproductive and prenatal genetics, including genetic controls, fertilization and implantation, in vitro culture of the human embryo for the study of post-implantation development, and more Identifies how researchers and clinicians can implement the latest genetic, epigenetic, and –omics based approaches

Early life Environmental Exposure and Disease

Early life Environmental Exposure and Disease Book
Author : Yankai Xia
Publisher : Springer Nature
Release : 2020-07-09
ISBN : 9811537976
Language : En, Es, Fr & De

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Book Description :

This book offers valuable insights into the latest concepts and findings from epidemiologic, clinical and basic studies in the burgeoning area of early-life environmental exposure and diseases. The book is divided into five parts, starting with an overview of environmental exposure measurement and evaluation, followed by a review of the effects of exposure to various substances like tobacco smoke, pesticides and metals as well as stress on offspring’s health. It then discusses the developmental origins of a range of childhood diseases that affect growth, neural development and the immune system, and highlights the importance of longitudinal studies that measure exposure at potentially sensitive time points during childhood. It also provides up-to-date evidence of the intergenerational/transgenerational effects of early-life environmental exposure, especially via genetic and epigenetic pathways. Allowing readers to gain a thorough understanding of the predominating aspects of early-life environmental exposure and diseases, the book also provides a basis for developing environmental and health policies that could have wide and long-term impacts on human health.

Epigenetics in Society

Epigenetics in Society Book
Author : Windsor Epigenetics Study Group
Publisher : University of Windsor
Release : 2015-10-26
ISBN : 0920233724
Language : En, Es, Fr & De

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Book Description :

This is a book written by students of diverse disciplines, and intended for students and educated lay people. We intend this book to serve several functions. First, we want to make the field of epigenetics accessible to lay readers. Second, and more importantly, we want to excite further interest and concern regarding the social, ethical, legal, health, and policy implications that this field will have for all arenas of our lives. Third, we want to arm our readers with knowledge and wariness so that they can understand and critique the nuanced debates that will inevitably arise when costs and benefits must be weighed: while the effects of epigenetics upon us as individuals may be subtle, the demographic implications and costs are huge.