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Epigenetics and Metabolomics

Epigenetics and Metabolomics Book
Author : Paban K. Agrawala,Poonam Rana
Publisher : Academic Press
Release : 2021-08-15
ISBN : 9780323856522
Language : En, Es, Fr & De

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Book Description :

Epigenetics and Metabolomics, a new volume in the Translational Epigenetics series, offers a synthesized discussion of epigenetic control of metabolic activity, and systems-based approaches for better understanding these mechanisms. Over a dozen chapter authors provide an overview of epigenetics in translational medicine and metabolomics techniques, followed by analyses of epigenetic and metabolomic linkage mechanisms likely to result in effective identification of disease biomarkers, as well as new therapies targeting the removal of the inappropriate epigenetic alterations. Epigenetic interventions in cancer, brain damage, and neuroendocrine disease, among other disorders, are discussed in-depth, with an emphasis on exploring next steps for clinical translation and personalized healthcare. Offers a synthesized discussion of epigenetic regulation of metabolic activity and systems-based approaches to power new research Discusses epigenetic control of metabolic pathways and possible therapeutic targets for cancer, neurodegenerative, and neuroendocrine diseases, among others Provides guidance in epigenomics and metabolomic research methodology

Metabolomics for Biomedical Research

Metabolomics for Biomedical Research Book
Author : Jerzy Adamski
Publisher : Academic Press
Release : 2020-04
ISBN : 0128127848
Language : En, Es, Fr & De

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Book Description :

Metabolomics for Biomedical Research brings together recent progress on study design, analytics, biostatistics and bioinformatics for the success of metabolomics research. Metabolomics represents a very interdisciplinary research prominent in the functional analyses of living systems; hence, this book focuses on translation and medical aspects. The book discusses topics such as biomarkers and their requirements to be used in medical research, with the parameters and approaches on how to validate their quality; and animal models and other approaches, as stem cells and organoid culture. Additionally, it explains how metabolomics may be applied in prediction of individual response to drug or disease progression. This book is a valuable source for researchers on systems biology and other members of biomedical field interested in metabolism-oriented studies for medical research.

Genomics Proteomics and Metabolomics in Nutraceuticals and Functional Foods

Genomics  Proteomics and Metabolomics in Nutraceuticals and Functional Foods Book
Author : Debasis Bagchi,Francis Lau,Anand Swaroop,Manashi Bagchi
Publisher : John Wiley & Sons
Release : 2015-10-19
ISBN : 1118930428
Language : En, Es, Fr & De

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Book Description :

Functional foods and nutraceuticals have received considerable interest in the past decade, largely due to increasing consumer awareness of the health benefits associated with food. Diet in human health is no longer a matter of simple nutrition: consumers are more proactive and increasingly interested in the health benefits of functional foods and their role in the prevention of illness and chronic conditions. This, combined with an aging population that focuses not only on longevity but also quality of life, has created a market for functional foods and nutraceuticals. A fully updated and revised second edition, "Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods" reflects the recent upsurge in "omics" technologies and features 48 chapters that cover topics including genomics, proteomics, metabolomics, epigenetics, peptidomics, nutrigenomics and human health, transcriptomics, nutri-ethics, and nanotechnology. This cutting-edge volume, written by a panel of experts from around the globe, reviews the latest developments in the field with an emphasis on the application of these novel technologies to functional foods and nutraceuticals. About the editorsDebasis Bagchi, Ph.D., MACN, CNS, MAIChEUniversity of Houston College of Pharmacy, Houston, TX, USA Anand Swaroop, Ph.D.Cepham Inc., Piscataway, NJ, USA Manashi Bagchi, Ph.D., FACNCepham Inc., Piscataway, NJ, USA Also available from Wiley "Bio-Nanotechnology: A Revolution in Food, Biomedical and Health Sciences"Edited by Debasis Bagchi, Manashi Bagchi, Hiroyoshi Moriyama, Fereidoon ShahidiISBN: 978-0-470-67037-8 "Antioxidants and Functional Components in Aquatic Foods"Edited by Hordur G. KristinssonISBN: 978-0-8138-1367-7 "Nanotechnology and Functional Foods: Effective Delivery of Bioactive Ingredients"Edited by Cristina Sabliov, Hongda Chen, Rickey YadaISBN: 978-1-118-46220-1

Advances in Clinical Chemistry

Advances in Clinical Chemistry Book
Author : Gregory S. Makowski
Publisher : Academic Press
Release : 2020-01-10
ISBN : 0128208015
Language : En, Es, Fr & De

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Book Description :

Advances in Clinical Chemistry, Volume 94, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest technologies relating to the field of clinical chemistry, with specific chapters in this new release covering Hypertensive disorders of pregnancy: Strategy to develop clinical peptide biomarkers for more accurate evaluation of the pathophysiological status of this syndrome, Clotting factors - Clinical biochemistry and their roles as plasma enzymes, Myokines: The endocrine coupling of skeletal muscle and bone, Epigenetic reprogramming and potential application of epigenetic-modifying drugs in acquired chemotherapeutic resistance, and more. Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science Authored by world renowned clinical laboratory scientists, physicians and research scientists Presents the international benchmark for novel analytical approaches in the clinical laboratory

Medicine for MRCP

Medicine for MRCP Book
Author : Rupa Bessant
Publisher : Oxford Specialty Training: Revision Texts
Release : 2020-03-23
ISBN : 019877950X
Language : En, Es, Fr & De

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Book Description :

Medicine for MRCP provides a comprehensive review of the material that you need to pass the MRCP Parts 1 and 2 written papers. The twenty-seven chapters mapped out to the RCP syllabus, cover all areas from molecular medicine and genetics, through to medical law and ethics. Written by specialist contributors and educational experts, the content is carefully crafted to build your understanding for both papers. Each chapter begins with the basic science required for Part 1, before covering clinical medicine for Part 1, Part 2 and the PACES examinations. To ensure effective revision, material is presented in short sections with bullet lists, tables, and boxes. Over 150 drawings and photos illustrate key principles and clinical topics making them easier to retain. References to evidence-based protocols and directions to further reading allow for deeper understanding. Candidates can review their progress via the 180 end-of chapter self-assessment questions. Drawing on the authors' expertise, Medicine for MRCP is the ideal companion for the MRCP as well as a useful reference guide for practicing medical doctors.

Physiological Nitrogen Isotopic Responses in Paracoccus Denitrificans

Physiological Nitrogen Isotopic Responses in Paracoccus Denitrificans Book
Author : Bruce Sean Pan
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The natural abundances of stable isotopes in our environment serve as intrinsic tracers that are incorporated into biological compounds and create unique isotopic signatures that record molecular history. Use of stable isotopes in the investigation of biochemical, geological, and forensic applications has become increasingly popular in the past two decades, in large part due to the recent development of requisite instrumentation capable of measuring the subtle variations of naturally occurring isotope ratios. Progress towards a universal model describing the behavior of isotopes in physiology has seen little consolidation due to the empirical nature of isotopic response. Elucidation of underlying mechanisms requires tightly controlled experiments with careful isotopic characterization of specific physiological states.

Toxicology and Epigenetics

Toxicology and Epigenetics Book
Author : Saura C. Sahu
Publisher : John Wiley & Sons
Release : 2012-08-23
ISBN : 1118349067
Language : En, Es, Fr & De

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Book Description :

Epigenetics is the study of both heritable and non-heritablechanges in the regulation of gene activity and expression thatoccur without an alteration in the DNA sequence. Thisdynamic and rapidly developing discipline is making its impactacross the biomedical sciences, in particular in toxicology whereepigenetic differences can mean that different individuals responddifferently to the same drug or chemical. Toxicology and Epigenetics reflects the multidimensionalcharacter of this emerging area of toxicology, describingcutting-edge molecular technologies to unravel epigenetic changes,the use of in vivo and in vitro models, as well asthe potential use of toxicological epigenetics in regulatoryenvironments. An international team of experts consider theinterplay between epigenetics and toxicology in a number of areas,including environmental, nutritional, pharmacological, andcomputational toxicology, nanomaterials, proteomics andmetabolomics, and cancer research. Topics covered include: environment, epigenetics and diseases DNA methylation and toxicogenomics chromatin at the intersection of disease and therapy epigenomic actions of environmental arsenicals environment, epigenetics and cardiovascular health toxicology, epigenetics and autoimmunity ocular epigenomics: potential sites of environmental impact indevelopment and disease nuclear RNA silencing and related phenomena in animals epigenomics – impact for drug safety sciences methods of global epigenomic profiling transcriptomics: applications in epigenetic toxicology Toxicology and Epigenetics is an essential insight intothe current trends and future directions of research in thisrapidly expanding field for investigators, toxicologists, riskassessors and regulators in academia, industry and government.

Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2013

Departments of Labor  Health and Human Services  Education  and Related Agencies Appropriations for 2013 Book
Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publisher : Unknown
Release : 2012
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2013 book written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Fundamentals of Advanced Omics Technologies From Genes to Metabolites

Fundamentals of Advanced Omics Technologies  From Genes to Metabolites Book
Author : Anonim
Publisher : Elsevier
Release : 2014-04-21
ISBN : 9780444626516
Language : En, Es, Fr & De

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Book Description :

Fundamentals of Advanced Omics Technologies: From Genes to Metabolites covers the fundamental aspects of the new instrumental and methodological developments in omics technologies, including those related to genomics, transcriptomics, epigenetics, proteomics and metabolomics, as well as other omics approaches such as glycomics, peptidomics and foodomics. The principal applications are presented in the following complementary volume. The chapters discuss in detail omics technologies, DNA microarray analysis, next-generation sequencing technologies, genome-wide analysis of methylation and histone modifications, emerging nanotechniques in proteomics, imaging mass spectrometry in proteomics, recent quantitative proteomics approaches, and advances in high-resolution NMR-based metabolomics, as well as MS-based non-targeted metabolomics and metabolome analysis by CE-MS, global glycomics analyses, foodomics, and high resolution analytical tools for quantitative peptidomics. Key aspects related to chemometrics, bioinformatics, data treatment, data integration and systems biology, deep-sequencing data analysis, statistical approaches for the analysis of microarray data, the integration of transcriptome and metabolome data and computational approaches for visualization and integration of omics data are also covered. Covers the latest advances in instrumentation, experimental design, sample preparation, and data analysis Provides thorough explanations and descriptions of specific omics technologies Describes advanced tools and methodologies for data pretreatment, storage, curation and analysis, as well as data integration

New Scientist

New Scientist Book
Author : Anonim
Publisher : Unknown
Release : 2009
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download New Scientist book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Comprehensive Foodomics

Comprehensive Foodomics Book
Author : Anonim
Publisher : Elsevier
Release : 2020-11-12
ISBN : 0128163968
Language : En, Es, Fr & De

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Book Description :

Comprehensive Foodomics offers a definitive collection of over 150 articles that provide researchers with innovative answers to crucial questions relating to food quality, safety and its vital and complex links to our health. Topics covered include transcriptomics, proteomics, metabolomics, genomics, green foodomics, epigenetics and noncoding RNA, food safety, food bioactivity and health, food quality and traceability, data treatment and systems biology. Logically structured into 10 focused sections, each article is authored by world leading scientists who cover the whole breadth of Omics and related technologies, including the latest advances and applications. By bringing all this information together in an easily navigable reference, food scientists and nutritionists in both academia and industry will find it the perfect, modern day compendium for frequent reference. List of sections and Section Editors: Genomics - Olivia McAuliffe, Dept of Food Biosciences, Moorepark, Fermoy, Co. Cork, Ireland Epigenetics & Noncoding RNA - Juan Cui, Department of Computer Science & Engineering, University of Nebraska-Lincoln, Lincoln, NE Transcriptomics - Robert Henry, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, St Lucia, Australia Proteomics - Jens Brockmeyer, Institute of Biochemistry and Technical Biochemistry, University Stuttgart, Germany Metabolomics - Philippe Schmitt-Kopplin, Research Unit Analytical BioGeoChemistry, Neuherberg, Germany Omics data treatment, System Biology and Foodomics - Carlos Leon Canseco, Visiting Professor, Biomedical Engineering, Universidad Carlos III de Madrid Green Foodomics - Elena Ibanez, Foodomics Lab, CIAL, CSIC, Madrid, Spain Food safety and Foodomics - Djuro Josić, Professor Medicine (Research) Warren Alpert Medical School, Brown University, Providence, RI, USA & Sandra Kraljević Pavelić, University of Rijeka, Department of Biotechnology, Rijeka, Croatia Food Quality, Traceability and Foodomics - Daniel Cozzolino, Centre for Nutrition and Food Sciences, The University of Queensland, Queensland, Australia Food Bioactivity, Health and Foodomics - Miguel Herrero, Department of Bioactivity and Food Analysis, Foodomics Lab, CIAL, CSIC, Madrid, Spain Brings all relevant foodomics information together in one place, offering readers a ‘one-stop,’ comprehensive resource for access to a wealth of information Includes articles written by academics and practitioners from various fields and regions Provides an ideal resource for students, researchers and professionals who need to find relevant information quickly and easily Includes content from high quality authors from across the globe

Human and Animal Models for Translational Research on Neurodegeneration Challenges and Opportunities From South America

Human and Animal Models for Translational Research on Neurodegeneration  Challenges and Opportunities From South America Book
Author : Agustín Ibáñez,Lucas Sedeño,Adolfo M. García,Robert M.J. Deacon,Patricia Cogram
Publisher : Frontiers Media SA
Release : 2018-06-21
ISBN : 2889454940
Language : En, Es, Fr & De

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Book Description :

Neurodegenerative diseases are the most frequent cause of dementia, representing a burden for public health systems (especially in middle and middle-high income countries). Although most research on this issue is concentrated in first-world centers, growing efforts in South America are affording important breakthroughs. This emerging agenda poses new challenges for the region but also new opportunities for the field. This book aims to integrate the community of experts across the globe and the region, and to establish new challenges and developments for future investigation. We present research focused on neurodegenerative research in South America. We introduce studies assessing the interplay among genetic, neural, and behavioral dimensions of these diseases, as well as articles on vulnerability factors, comparisons of findings from various countries, and works promoting multicenter and collaborative networking. More generally, our book covers a broad scope of human-research approaches (behavioral assessment, neuroimaging, electromagnetic techniques, brain connectivity, peripheral measures), animal methodologies (genetics, epigenetics, proteomics, metabolomics, other molecular biology tools), species (all human and non-human animals, sporadic, and genetic versions), and article types (original research, review, and opinion papers). Through this wide-ranging proposal, we hope to introduce a fresh approach to the challenges and opportunities of research on neurodegeneration in South America.

Handbook of Statistical Genomics

Handbook of Statistical Genomics Book
Author : David J. Balding,Ida Moltke,John Marioni
Publisher : John Wiley & Sons
Release : 2019-09-16
ISBN : 1119429145
Language : En, Es, Fr & De

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Book Description :

A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.

Recent Trends and Techniques in Plant Metabolic Engineering

Recent Trends and Techniques in Plant Metabolic Engineering Book
Author : Sudesh Kumar Yadav,Vinay Kumar,Sudhir P Singh
Publisher : Springer
Release : 2018-11-23
ISBN : 9811322511
Language : En, Es, Fr & De

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Book Description :

Remarkable research has yielded whole genome data in plants, resulting in the documentation of an ever-increasing number of genes, without establishing their functions. The huge data resources available at the genome, transcriptome, proteome and metabolome levels are of enormous value in the field of functional genomics. This book provides insights into interpreting the sea of data in order to understand basic and practical aspects of plant metabolic engineering. It discusses in detail ways to tap into this enormous pool of data to increase productivity, and offers information that is both interesting and necessary for exploring the manipulation of metabolic pathways. The interdisciplinary approaches presented here also serve as a source of ideas for practical applications.

Translational Systems Medicine and Oral Disease

Translational Systems Medicine and Oral Disease Book
Author : Stephen Sonis,Alessandro Villa
Publisher : Academic Press
Release : 2019-09-14
ISBN : 0128137630
Language : En, Es, Fr & De

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Book Description :

Translational Systems Medicine and Oral Disease bridges the gap between discovery science and clinical oral medicine, providing opportunities for both the scientific and clinical communities to understand how to apply recent findings in cell biology, genomic profiling, and systems medicine to favorably impact the diagnosis, treatment and management of oral diseases. Fully illustrated chapters from leading international contributors explore clinical applications of genomics, proteomics, metabolomics, microbiomics and epigenetics, as well as analytic methods and functional omics in oral medicine. Disease specific chapters detail systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease, and autoimmune disease, among others. In addition, the book emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology and primary care. Presents the work of leading international researchers and clinicians who speak on the clinical applications of genomics, proteomics, metabolomics, microbiomics, and epigenetics, as well as analytic methods and functional omics in oral medicine Provides full-color, richly illustrated chapters that examine systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease and autoimmune diseases Includes clinical case studies that illustrate examples of oral disease diagnostics and management, highlighting points of key importance for the reader Emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers, and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology, and primary care

Trends in Personalized Nutrition

Trends in Personalized Nutrition Book
Author : Charis M. Galanakis
Publisher : Academic Press
Release : 2019-05-23
ISBN : 0128172657
Language : En, Es, Fr & De

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Book Description :

Trends in Personalized Nutrition explores the topic of personalized nutrition from multiple angles, addressing everything from consumer acceptance, to policies and cognitive dissonance. Sections in the book cover epigenetics, nutrigenomics, predicting glycemic response, and metabolomics and the role of bacteria. In addition, the book explores diet, obesity and personalized nutrition for athletes, women, and infants and children, along with a section on the role of modern technology in the promotion of personalized nutrition. Nutritionists, food technologists, food chemists, new product developers, academics, and researchers and physicians working in the field of nutrition will find this to be a great reference. Addresses consumer acceptance, policies and cognitive dissonance in nutrition Discusses epigenetics, nutrigenomics, how to predict glycemic response, and metabolomics and the role of bacteria Explores diet and obesity Considers personalized nutrition for athletes, women, infants and children Contemplates the role of modern technology in personalized nutrition

The Metabolomics of Chronic Stress

The Metabolomics of Chronic Stress Book
Author : Constance Ananta Sobsey
Publisher : Unknown
Release : 2016
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The World Health Organization has called stress-related illness "the health epidemic of the 21st century." While the biochemical pathways associated with the acute stress response are well-characterized, many of the pathways behave differently under conditions of chronic stress. The purpose of this project is to apply high-sensitivity mass spectrometry (MS)-based targeted and untargeted metabolomics approaches to generate new insights into the biochemical processes and pathways associated with the chronic stress response, and potential mechanisms by which chronic stress produces adverse health effects. Chapter 1 describes the application of sets of targeted and untargeted metabolomics approaches to analyze serum samples from a human epigenetic model of chronic stress in order to identify potential targets for further analysis. To test the resulting hypothesis that oxidative stress is a key feature of chronic stress, a new targeted multiple reaction monitoring (MRM)-MS assay was developed for the accurate quantitation of aldehyde products of lipid peroxidation, as described in Chapter 2. In Chapter 3, the validated method for quantitation of malondialdehyde (MDA) was t applied to mouse plasma samples from a model of chronic social defeat stress to determine whether animals exposed to psychosocial stress show increases in oxidative stress. Mouse plasma samples from this model were also analyzed by untargeted metabolomics using Fourier-transform (FT)-MS to identify other important metabolite features, particularly those that overlap with metabolites identified in the human epigenetic model. Analysis of metabolomic data from two very different models of chronic stress supports the consistent detection of a metabolomic phenotype for chronic stress that is characterized by the dysregulation of energy metabolism associated with decreased concentrations of diacyl-phospholipids in blood. Increased blood concentrations of fatty acids, carnitines, acylcarnitines, and ether phospholipids were also observed. In addition to metabolites associated with energy metabolism, chronic stress also significantly influenced metabolites associated with amino acid metabolism and cell death. This characteristic pattern of differences in metabolite concentrations was observed in the plasma of mice exposed to chronic social defeat stress, irrespective of whether or not they displayed outward signs of a chronic stress response; In fact, mice that were "resilient" to the behavioural effects of chronic social defeat stress displayed an exaggerated phenotype over mice that showed depressive-like symptoms following chronic stress exposure. This may suggest that the observed changes in fatty acid composition are protective against stress. However, changes in fatty acid composition are also known to be associated with a wide variety of pathologies including heart disease, neurodegenerative diseases, and mood disorders, so the lipidomic changes associated with chronic stress may also contribute to its health impact. Overall, the results provide further evidence that changes in energy metabolism are a central part of allostatic adaptation to chronic stress.

Plant Genetics and Molecular Biology

Plant Genetics and Molecular Biology Book
Author : Rajeev K. Varshney,Manish K. Pandey,Annapurna Chitikineni
Publisher : Springer
Release : 2018-09-04
ISBN : 3319913131
Language : En, Es, Fr & De

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Book Description :

This book reviews the latest advances in multiple fields of plant biotechnology and the opportunities that plant genetics, genomics and molecular biology have offered for agriculture improvement. Advanced technologies can dramatically enhance our capacity in understanding the molecular basis of traits and utilizing the available resources for accelerated development of high yielding, nutritious, input-use efficient and climate-smart crop varieties. In this book, readers will discover the significant advances in plant genetics, structural and functional genomics, trait and gene discovery, transcriptomics, proteomics, metabolomics, epigenomics, nanotechnology and analytical & decision support tools in breeding. This book appeals to researchers, academics and other stakeholders of global agriculture.

Medical Biotechnology

Medical Biotechnology Book
Author : Judit Pongracz,Mary Keen
Publisher : Elsevier Health Sciences
Release : 2009
ISBN : 0080451357
Language : En, Es, Fr & De

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Book Description :

"Biotechnology encompasses the variety of methods available for manipulating living cells and organisms. It is having an increasing impact on all aspects of medicine, from helping in the understanding of the aetiology of disease, to its diagnosis and treatment. This growing importance of medical biotechnology means that a general understanding of this rapidly advancing field is essential for all medical graduates and medical scientists. This book places emphasis on the medical applications of biotechnology, rather than the details fo the experimental techniques"--Back cover.

Trauma Ninth Edition

Trauma  Ninth Edition Book
Author : Ernest E. Moore,David V. Feliciano,Kenneth L. Mattox
Publisher : McGraw Hill Professional
Release : 2020-09-22
ISBN : 126014335X
Language : En, Es, Fr & De

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Book Description :

The world’s leading resource for to diagnosing and treating any injury—quickly, safely, and effectively Unparalleled in its breadth and depth of expertly crafted content, Trauma takes you through the full range of injuries you are likely to encounter. With a full-color atlas of anatomic drawings and surgical approaches, this trusted classic provides thorough coverage of kinematics and the mechanisms of trauma injury, the epidemiology of trauma, injury prevention, the basics of trauma systems, triage, and transport, and more. It then reviews generalized approaches to the trauma patient, from pre-hospital care and managing shock, to emergency department thoracotomy and the management of infections; delivers a clear, organ-by-organ survey of treatment protocols; and shows how to handle specific challenges in trauma―including alcohol and drug abuse, and combat-related wounds―in addition to post-traumatic complications such as multiple organ failure. 500 photos and illustrations Color atlas Numerous X-rays, CT scans, and algorithms High-yield section on specific approaches to the trauma patient A-to-Z overview of management of specific traumatic injuries Detailed discussion of the management of complications