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Eosinophils In Health And Disease

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Eosinophils in Health and Disease

Eosinophils in Health and Disease Book
Author : James J. Lee,Helene F. Rosenberg
Publisher : Academic Press
Release : 2012-11-02
ISBN : 012394385X
Language : En, Es, Fr & De

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Book Description :

Eosinophils in Health and Disease provides immunology researchers and students with a comprehensive overview of current thought and cutting-edge eosinophil research, providing chapters on basic science, disease-specific issues, therapeutics, models for study and areas of emerging importance.

Chronic Rhinosinusitis

Chronic Rhinosinusitis Book
Author : Wytske J. Fokkens
Publisher : Immunology and Allergy Clinics
Release : 2009
ISBN : 9781437712308
Language : En, Es, Fr & De

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Book Description :

This issue will focus on treatments for Chronic Rhinosinusitis. Dr. Wyste Fokkens guest edits topics such as: "Inflammatory mechanisms in chronic rhinosinusitis with or without nasal polyposis," "European versus Asian Chronic rhinosinusitis. What did it teach us and what do we want to know," "Epithelium, cilia and mucus, their importance in chronic rhinosinusitis Noam Cohen Noam," "Aspirin intolerance: does desensitization alter the course of the disease," "Anti-inflammatory effects of macrolides: applications in CRS," and more!

The Saint Chopra Guide to Inpatient Medicine

The Saint Chopra Guide to Inpatient Medicine Book
Author : Sanjay Saint,Vineet Chopra
Publisher : Oxford University Press
Release : 2018-11-09
ISBN : 0190862823
Language : En, Es, Fr & De

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Book Description :

THE DEFINITIVE GUIDE TO INPATIENT MEDICINE, UPDATED AND EXPANDED FOR A NEW GENERATION OF STUDENTS AND PRACTITIONERS A long-awaited update to the acclaimed Saint-Frances Guides, the Saint-Chopra Guide to Inpatient Medicine is the definitive practical manual for learning and practicing inpatient medicine. Its end-to-end coverage of the specialty focuses on both commonly encountered problems and best practices for navigating them, all in a portable and user-friendly format. Composed of lists, flowcharts, and "hot key" clinical insights based on the authors' decades of experience, the Saint-Chopra Guide ushers clinicians through common clinical scenarios from admission to differential diagnosis and clinical plan. It will be an invaluable addition -- and safety net -- to the repertoire of trainees, clinicians, and practicing hospitalists at any stage of their career.

The Eosinophil in Health and Disease

The Eosinophil in Health and Disease Book
Author : Adel A. F. Mahmoud,Karl Frank Austen,Arlene Stolper Simon
Publisher : Saunders
Release : 1980
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Eosinophil in Health and Disease book written by Adel A. F. Mahmoud,Karl Frank Austen,Arlene Stolper Simon, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Pathogenic Advances and Therapeutic Perspectives for Eosinophilic Inflammation

Pathogenic Advances and Therapeutic Perspectives for Eosinophilic Inflammation Book
Author : Florence E. Roufosse,Mats W. Johansson
Publisher : Frontiers Media SA
Release : 2018-12-06
ISBN : 2889456242
Language : En, Es, Fr & De

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Book Description :

With the recent approval of the first eosinophil-depleting therapeutic agents targeting the IL-5 pathway for treatment of severe eosinophilic asthma, eosinophils and eosinophilic disorders are in the limelight. Indeed, setbacks during clinical development of these compounds have revealed how much remains to be known about eosinophil biology in vivo, and have nurtured profuse research both on basic eosinophil biology and on pathogenic disease mechanisms, in order to better delineate the most meaningful targets for innovative therapeutic strategies. On one hand, variable degrees of eosinophil depletion observed in some compartments during IL-5-targeted treatment indicate that certain eosinophil subsets may not rely on this cytokine and/or that other important pro-eosinophilic mediators and signaling pathways are operative in vivo. On the other hand, it is increasingly clear that disorders involving eosinophils such as asthma are the final outcome of complex interactions between diverse cell types and mediators, beyond eosinophils and IL-5. These include type 2 helper T (Th2) cells and innate lymphoid cells, mast cells, and a variety of factors that either activate eosinophils or are released by them. Although a considerable amount of research has focused on asthma because it is a common condition and because management of severe asthma remains a major challenge, several rare eosinophilic disorders with more homogenous features have proven to be extremely useful models to reach a better understanding of the involvement of eosinophils in tissue damage and dysfunction, and of the micro-environmental interactions operating within the complex network of eosinophilic inflammation. Unraveling this interplay has resulted in advances in the development of molecular tools to detect disease subsets and to monitor therapeutic responses, and in identification of promising new therapeutic targets. This Research Topic dedicated to eosinophilic conditions covers aspects of the biology of eosinophils and closely related cells of particular relevance for drug development, reports on translational research investigating pathogenic mechanisms of specific eosinophilic disorders in humans that will likely result in significant changes in the way patients are managed, and presents an overview of the current advancement of targeted drug development for these conditions, with a special focus on asthma.

Eosinophilic Gastrointestinal Diseases

Eosinophilic Gastrointestinal Diseases Book
Author : Glenn T. Furuta,Dan Atkins
Publisher : W B Saunders Company
Release : 2009
ISBN : 9781437704891
Language : En, Es, Fr & De

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Book Description :

Drs. Glen Furuta and Dan Atkins have assembled an in-depth look at Eosinophilic Gastrointestinal Diseases as related to allergy with topics such as "Basic pathogenetic mechanisms of Eosinophilic Esophagitis", "Nutritional management of patients with food allergies and EGIDs", "Chemotactic factors role in EGIDs", "Biomarkers associated with allergic diseases", "Association of other allergic diseases with EGIDs" and much more!

Eosinophils in Health and Disease

Eosinophils in Health and Disease Book
Author : James J. Lee,Helene F. Rosenberg
Publisher : Elsevier
Release : 2012-12-31
ISBN : 0123946077
Language : En, Es, Fr & De

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Book Description :

Written and edited by leaders in the field, Eosinophils in Health and Disease provides immunology researchers and students with a comprehensive overview of current thought and cutting-edge eosinophil research, providing chapters on basic science, disease-specific issues, therapeutics, models for study and areas of emerging importance. Despite an explosion of discovery in this area over the last decade, this is the only up-to-date resource on eosinophils and eosinophilia exists. This full-color volume provides an essential collection of world class information that is a must-have for any immunologist’s workbench or bookshelf. The only updated, comprehensive source of information on eosinophils on the market Written by over 80 leaders in the field Holistic view of the subject, including basic science, disease-specific chapters, therapeutic options and emerging areas of research

Mast Cells and Basophils

Mast Cells and Basophils Book
Author : Gianni Marone,Lawrence M. Lichtenstein,Federica J. Galli
Publisher : Academic Press
Release : 2000-05-25
ISBN : 0080535852
Language : En, Es, Fr & De

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Book Description :

Mast Cells and Basophils will be essential reading for immunologists, biochemists and medical researchers. Detailed chapters cover all aspects of mast cell and basophil research, from cell development, proteases, histamine, cysteinyl leukotrienes, physiology and pathology to the role of these cells in health and disease. Chapters also discuss the clinical implications of histamine receptor antagonists.

Oxford Handbook of Respiratory Medicine

Oxford Handbook of Respiratory Medicine Book
Author : Stephen Chapman,Grace Robinson,John Stradling,John Wrightson,Sophie West
Publisher : Oxford University Press, USA
Release : 2014
ISBN : 0198703864
Language : En, Es, Fr & De

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Book Description :

Respiratory ailments are the most common reason for emergency admission to hospital, the most common reason to visit the GP, and cost the NHS more than any other disease area. This pocket-sized handbook allows instant access to a wealth of information needed in the day-to-day practice of respiratory medicine.

Cells of the Immune System

Cells of the Immune System Book
Author : Ota Fuchs,Seyyed Shamsadin Athari
Publisher : BoD – Books on Demand
Release : 2020-05-13
ISBN : 1789855837
Language : En, Es, Fr & De

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Book Description :

The cells of the immune system are lymphocytes (T-cells, B-cells and NK (natural killer) cells), neutrophils, eosinophils, and monocytes/macrophages. This book is an overview of some types of these cells and their role in recognizing and/or reacting against foreign material. The immune system is characterized by collaboration between cells and proteins. The development of all cells of the immune system begins in the bone marrow with a hematopoietic stem cell. Two chapters deal with neutrophils, three chapters with T-cells, four chapters with eosinophils, and other chapters review the immunomodulation of macrophages, the role of transcription factor KLF4 in regulating plasticity of myeloid-derived suppressor cells, immune reconstitution after allogeneic hematopoietic stem cell transplantation, and role of sorption detoxification in the therapy of acute radiation sickness.

Janeway s Immunobiology

Janeway s Immunobiology Book
Author : Kenneth M. Murphy
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Janeway s Immunobiology book written by Kenneth M. Murphy, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Eosinophil Ultrastructure

Eosinophil Ultrastructure Book
Author : Rossana C.N. Melo,Ann M. Dvorak,Peter F. Weller
Publisher : Academic Press
Release : 2022-03-31
ISBN : 0128137568
Language : En, Es, Fr & De

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Book Description :

Eosinophil Ultrastructure: Atlas of Eosinophil Cell Biology and Pathology entirely focuses on eosinophils and their functional roles in inflammation, host defense, and normal homeostatic activities. The book explores the ultrastructure of human eosinophils, highlighting biological processes observed under normal, experimental, and pathological conditions. Created to fill a void in the eosinophil literature, the book includes an extensive array of electron microscopic images that illustrate the diversity of eosinophil morphology. While the atlas is a learning and teaching tool, it is mainly a helpful resource for researchers to identify distinguishing features and structural changes that arise during studies of human eosinophils. The book also covers the ultrastructure of mouse eosinophils under normal and activation conditions and in the context of representative diseases. Gives guidelines to understand the human eosinophils in studies focused on structural biology, cellular immunology, innate and adaptive immunity, immune responses to pathogens, immunopathology, and inflammatory responses Provides a core of essential knowledge to identify both immature and mature eosinophils Comprises a representative compilation of the eosinophil ultrastructure during biological processes, such as activation and degranulation, mostly under experimental conditions Highlights eosinophil biological processes found in vivo during human diseases, thus providing a link between basic science and clinical aspects Helps identify distinguishing features and structural changes that arise during studies of human eosinophils after isolation from body fluids, while in cultures, or biopsies Explains the ultrastructural organization of mature and immature mouse eosinophils, highlighting the similarities/differences between them and human eosinophils

Neonatal Hematology

Neonatal Hematology Book
Author : Pedro A. de Alarcón,Eric J. Werner,Robert D. Christensen,Martha C. Sola-Visner
Publisher : Cambridge University Press
Release : 2021-02-18
ISBN : 1108488986
Language : En, Es, Fr & De

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Book Description :

An essential guide to the pathogenesis, diagnosis and management of hematologic problems in the neonate, covering erythrocyte disorders, leukocyte disorders, immunologic disorders and hemostatic disorders. Guidance is practical, including blood test interpretation, advice on transfusions and reference ranges for hematological values.

Proteins Form and Function

Proteins  Form and Function Book
Author : R.A. Bradshaw,M. Purton
Publisher : Elsevier
Release : 2012-12-02
ISBN : 0080983936
Language : En, Es, Fr & De

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Book Description :

Proteins are of fundamental importance in all aspects of cell structure and function. The study of proteins has always formed a central part of biochemistry, and recent expansion in the range and sophistication of available techniques has provided a wealth of new information. The current methods and approaches used to gain a better understanding of the structure of proteins are described within this book, while other articles focus on the role of proteins within the cell. Most of the articles have appeared previously in the monthly review journal Trends in Biochemical Sciences (TIBS), with a few commissioned specifically for this collection, which should appeal to students, lecturers and researchers interested in the form and function of proteins.

Myeloid Cells in Health and Disease

Myeloid Cells in Health and Disease Book
Author : Siamon Gordon
Publisher : John Wiley & Sons
Release : 2020-07-10
ISBN : 1555819192
Language : En, Es, Fr & De

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Book Description :

The structure, functions, and interactions of myeloid cells have long been the focus of research and therapeutics development. Yet, much more remains to be discovered about the complex web of relationships that makes up the immune systems of animals. Scientists today are applying genome-wide analyses, single-cell methods, gene editing, and modern imaging techniques to reveal new subclasses of differentiated myeloid cells, new receptors and cytokines, and important interactions among immune cells. In Myeloid Cells in Health and Disease: A Synthesis, Editor Siamon Gordon has assembled an international team of esteemed scientists to provide their perspectives of myeloid cells during innate and adaptive immunity. The book begins by presenting the foundational research of Paul Ehrlich, Elie Metchnikoff, and Donald Metcalf. The following chapters discuss evolution and the life cycles of myeloid cells; specific types of differentiated myeloid cells, including macrophage differentiation; and antigen processing and presentation. The rest of the book is organized by broad topics in immunology, including the recruitment of myeloid and other immune cells following microbial infection the role of myeloid cells in the inflammation process and the repair of damaged tissue the vast arsenal of myeloid cell secretory molecules, including metalloproteinases, tumor necrosis factor, histamine, and perforin receptors and downstream signaling pathways that are activated following ligand-receptor binding roles of myeloid cells during microbial and parasite infections contributions of myeloid cells in atherosclerosis myeloid-derived suppressor cells in tumor development and cancer Myeloid Cells in Health and Disease: A Synthesis will benefit graduate students and researchers in immunology, hematology, microbial pathogenesis, infectious disease, pathology, and pharmacology. Established scientists and physicians in these and related fields will enjoy the book's rich history of myeloid cell research and suggestions for future research directions and potential therapies.

Severe Asthma

Severe Asthma Book
Author : Kian Fan Chung,Elliot Israel,Peter G. Gibson
Publisher : European Respiratory Society
Release : 2019-06-01
ISBN : 1849841047
Language : En, Es, Fr & De

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Book Description :

Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.

Eosinophils

Eosinophils Book
Author : Garry M. Walsh
Publisher : Nova Biomedical Books
Release : 2012-01-01
ISBN : 9781619426412
Language : En, Es, Fr & De

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Book Description :

The eosinophil is an enigmatic cell with a continuing ability to fascinate. In this book, experts in the field of eosinophil biology comprehensively update our knowledge on the human eosinophil in health and disease. Topics discussed include a synopsis of eosinophil characteristics, properties and role in disease. Important information on how eosinophils release their potent and toxic granule proteins will be covered and how these basic proteins give rise to pathologies including issues such as the function of the nerves.

Chemokines in the Lung

Chemokines in the Lung Book
Author : Robert M. Strieter,Steven L. Kunkel,Theodore Standiford
Publisher : CRC Press
Release : 2003-01-22
ISBN : 0824747445
Language : En, Es, Fr & De

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Book Description :

This reference discusses the role of chemokines in mediating leukocyte trafficking, angiogenesis, tumor cell metastasis, host defense, trauma-induced lung injury, and the progression of AIDS in the lung, and studies cytokines as natural agents for modulating diseases that affect the lung.

Asthma

Asthma Book
Author : Celso Pereira
Publisher : BoD – Books on Demand
Release : 2019-10-02
ISBN : 1789843154
Language : En, Es, Fr & De

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Book Description :

Asthma is a prevalent disease in all age groups that results from different pathogenic mechanisms, cells, and mediators engaged in innumerous clinical phenotypes and endotypes. This book exhaustively and didactically explores the biological expression of numerous cells and mediators involved in bronchial inflammation. The information provided aims at identifying the diversity and complexity of the interrelationships between the different players, drawing attention to critical mechanisms in asthma. It also highlights the requirement of new tools to identify strong biomarkers absolutely critical for managing asthma.

Dermatological Signs of Systemic Disease E Book

Dermatological Signs of Systemic Disease E Book Book
Author : Jeffrey P. Callen,Joseph L. Jorizzo,John J. Zone,Warren Piette,Misha A. Rosenbach,Ruth Ann Vleugels
Publisher : Elsevier Health Sciences
Release : 2016-03-08
ISBN : 0323358314
Language : En, Es, Fr & De

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Book Description :

The new edition of Dermatological Signs of Systemic Disease helps you identify a full range of common and rare systemic diseases early on so they can be managed as effectively as possible. Formerly titled Dermatological Signs of Internal Disease, it takes an evidence-based approach to diagnosis and treatment, offering dependable clinical recommendations that enable you to attain definitive diagnoses of internal diseases that manifest on the skin. Allows you to attain definitive diagnoses of internal diseases that manifest on the skin. Uses a consistent, user-friendly format for easy reference. Covers hot topics such as lupus erythematosus, dermatomyositis, autoinflammatory diseases, eosinophilic and neutrophilic dermatoses, and psoriasis therapies and co-morbidities. Highlights newer therapies and treatment options for most diseases. Includes over 500 full-color illustrations - 200 new to this edition - that provide the best possible representations of diseases as they appear in the clinic. Features more viewpoints from an expanded team of nationally recognized experts in their respective fields.