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Eosinophil Ultrastructure

Eosinophil Ultrastructure Book
Author : Rossana C.N. Melo,Ann M. Dvorak,Peter F. Weller
Publisher : Academic Press
Release : 2021-12-14
ISBN : 9780323994132
Language : En, Es, Fr & De

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Book Description :

Eosinophil Ultrastructure: Atlas of Eosinophil Cell Biology and Pathology focuses on eosinophils and their functional roles in inflammation, host defense and normal homeostatic activities. The book explores the ultrastructure of human eosinophils, highlighting biological processes observed in normal, experimental and pathological conditions. Created to fill a void in the eosinophil literature, this book has an extensive array of electron microscopic images that illustrate the diversity of eosinophil morphology. While the atlas is primarily a learning and teaching tool, it also acts as a helpful resource for researchers who want to identify distinguishing features and structural changes that arise during studies of human eosinophils. Helps readers understand human eosinophils in studies focused on structural biology, cellular immunology, innate and adaptive immunity, immune responses to pathogens, immunopathology and inflammatory responses Provides a core of essential knowledge to identify both immature and mature eosinophils Comprises a representative compilation of the eosinophil ultrastructure during biological processes, such as activation and degranulation, observed mostly in experimental conditions Highlights eosinophil biological processes found in vivo during human diseases, thus providing a link between basic science and clinical aspects Helps identify distinguishing features and structural changes that arise during studies of human eosinophils in culture

Eosinophils in Health and Disease

Eosinophils in Health and Disease Book
Author : James J. Lee,Helene F. Rosenberg
Publisher : Academic Press
Release : 2012
ISBN : 012394385X
Language : En, Es, Fr & De

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Book Description :

Eosinophils in Health and Disease provides immunology researchers and students with a comprehensive overview of current thought and cutting-edge eosinophil research, providing chapters on basic science, disease-specific issues, therapeutics, models for study and areas of emerging importance.

Pathogenic Advances and Therapeutic Perspectives for Eosinophilic Inflammation

Pathogenic Advances and Therapeutic Perspectives for Eosinophilic Inflammation Book
Author : Florence E. Roufosse,Mats W. Johansson
Publisher : Frontiers Media SA
Release : 2018-12-06
ISBN : 2889456242
Language : En, Es, Fr & De

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Book Description :

With the recent approval of the first eosinophil-depleting therapeutic agents targeting the IL-5 pathway for treatment of severe eosinophilic asthma, eosinophils and eosinophilic disorders are in the limelight. Indeed, setbacks during clinical development of these compounds have revealed how much remains to be known about eosinophil biology in vivo, and have nurtured profuse research both on basic eosinophil biology and on pathogenic disease mechanisms, in order to better delineate the most meaningful targets for innovative therapeutic strategies. On one hand, variable degrees of eosinophil depletion observed in some compartments during IL-5-targeted treatment indicate that certain eosinophil subsets may not rely on this cytokine and/or that other important pro-eosinophilic mediators and signaling pathways are operative in vivo. On the other hand, it is increasingly clear that disorders involving eosinophils such as asthma are the final outcome of complex interactions between diverse cell types and mediators, beyond eosinophils and IL-5. These include type 2 helper T (Th2) cells and innate lymphoid cells, mast cells, and a variety of factors that either activate eosinophils or are released by them. Although a considerable amount of research has focused on asthma because it is a common condition and because management of severe asthma remains a major challenge, several rare eosinophilic disorders with more homogenous features have proven to be extremely useful models to reach a better understanding of the involvement of eosinophils in tissue damage and dysfunction, and of the micro-environmental interactions operating within the complex network of eosinophilic inflammation. Unraveling this interplay has resulted in advances in the development of molecular tools to detect disease subsets and to monitor therapeutic responses, and in identification of promising new therapeutic targets. This Research Topic dedicated to eosinophilic conditions covers aspects of the biology of eosinophils and closely related cells of particular relevance for drug development, reports on translational research investigating pathogenic mechanisms of specific eosinophilic disorders in humans that will likely result in significant changes in the way patients are managed, and presents an overview of the current advancement of targeted drug development for these conditions, with a special focus on asthma.

Ultrastructure of Human Sella Tumors

Ultrastructure of Human Sella Tumors Book
Author : A.M. Landolt
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3709184207
Language : En, Es, Fr & De

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Book Description :

This monograph on the "Ultrastructure of Human Sella Tumors" is in fact a study of the correlations of clinical findings and morphology. It is a timely and eagerly awaited publication because of the increasing interest of the endocrinologist in pituitary disorders and of the neuro surgeon in the newest aspects of surgery on pituitary tumors, and also because of the unsatisfactory but still widely accepted classification into eosinophil, basophil and chromophobe pituitary adenomas. This old classification has been mainly based on granule color as seen after hematoxylin-eosin staining, but it does not, after extensive clinical observations, reflect in many instances the type of clinical picture observed. The author has brilliantly succeeded in demonstrating in a convinc ing way, by an extensive study of the relevant literature and by his own histological work, that further insight into the biology of the hypophysis and of the pituitary tumor can be obtained only by newer methods of light microscopic staining, immuno-histochemistry and electron microscopy combined with radio-immunological blood hormone determination.

The Ultrastructure of Human Tumours

The Ultrastructure of Human Tumours Book
Author : Brian Eyden,S. Sankar Banerjee,Yongxin Ru,Paweł Liberski
Publisher : Springer Science & Business Media
Release : 2014-02-12
ISBN : 3642391680
Language : En, Es, Fr & De

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Book Description :

The Ultrastructure of Human Tumours: Applications in Diagnosis and Research describes the core features as seen by transmission electron microscopy, defining the different types of cellular differentiation in tumours; this is relevant for tumour nomenclature and diagnosis, which, in turn, are important for tumour pathologists in their collaboration with oncologists for the treatment of cancer patients. The book is divided into 8 chapters. Following an introduction on technique and procedure, there are chapters on epithelial tumours, melanocytic lesions, soft-tissue and related tumours, lymphoma and leukaemia, CNS neoplasms and neuroendocrine and neuronal tumours. Each chapter includes an introductory text that puts the ultrastructural features in the context of classical pathology. The book includes many new findings and interpretations from well-known tumours, as well as ultrastructural information on several newly described tumour entities not dealt with in existing tumour ultrastructure monographs. The book will especially be of value to tumour pathologists who need to solve problem cases with the aid of electron microscopy, but also to cancer research and tissue engineering scientists working to develop anti-cancer and stem-cell-based therapies. However, even those without access to electron microscopy may also benefit from this book, since many of the images provide an ‘explanation’ of the appearances of cells, tissues and tumours familiar to pathologists and scientists from light microscopy. In this respect, it is hoped that this book will stimulate the wider use of electron microscopy in pathology. The book is comprehensively referenced, 680 pages long and lavishly illustrated with 757 figures. Dr. Brian Eyden is Consultant Clinical Scientist and Dr. S. Sankar Banerjee Consultant Histopathologist in the Department of Histopathology, Christie NHS Foundation Trust, Manchester, UK; Dr. Yongxin Ru is Director of the Department of Electron Microscopy, Institute of Hematology and Blood Diseases Hospital, Tianjin, China; Paweł Liberski is Professor in the Department of Molecular Pathology and Neuropathology, Medical University Łódź, Poland.

Ultrastructural Pathology

Ultrastructural Pathology Book
Author : Norman F. Cheville
Publisher : John Wiley & Sons
Release : 2009-12-09
ISBN : 0813810345
Language : En, Es, Fr & De

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Book Description :

Ultrastructural Pathology, Second Edition is a comprehensive reference on electron microscopy of pathologic tissue in animals and humans. Now presented in an atlas format for easier identification of organelles, the text is designed to bridge the gap between what is seen in the electron microscope at the cellular level and what the pathologist encounters in the postmortem room. New to this edition are sections on diagnostic electron microscopy, providing information on specialized technologies for electron microscopy, and invertebrate pathology. Emphasizing comparative pathology, the book explains and integrates all aspects of cellular changes in lesions occurring from natural or experimental disease.

Ultrastructure of Mast Cells and Basophils

Ultrastructure of Mast Cells and Basophils Book
Author : Ann M. Dvorak
Publisher : Karger Medical and Scientific Publishers
Release : 2005-01-01
ISBN : 3805578644
Language : En, Es, Fr & De

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Book Description :

In this book, the author reviews the ultrastructural studies of basophils and mast cells performed since the publication of an earlier monograph in 1991. These studies include the use of ultrastructural rules that allow identification of basophils and mast cells in new circumstances. Including more than 180 excellent micrographs, this book will be of interest to basic scientists in immunology, cell biology, secretion and angiogenesis research, and histochemistry. As mast cells and basophils play a crucial role in various diseases, it will be essential reading for allergists, immunologists, dermatologists, hematologists, gastroenterologists, rheumatologists, neurologists, pathologists, pulmonologists, and cardiologists.

Ultrastructure of Haemic Cells

Ultrastructure of Haemic Cells Book
Author : J. C. Cawley,Frank George James Hayhoe
Publisher : Unknown
Release : 1973
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Ultrastructure of Haemic Cells book written by J. C. Cawley,Frank George James Hayhoe, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Ultrastructural Pathology of the Cell and Matrix

Ultrastructural Pathology of the Cell and Matrix Book
Author : Feroze N. Ghadially
Publisher : Butterworth-Heinemann
Release : 2013-10-22
ISBN : 1483192091
Language : En, Es, Fr & De

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Book Description :

Ultrastructural Pathology of the Cell and Matrix: Third Edition Volume 2 presents a comprehensive examination of the intracellular lesion. It discusses the analysis of pathological tissues using electron microscope. It addresses the experimental procedures made on the cellular level. Some of the topics covered in the book are the structure, distribution, and variations of rod-shaped microtubulated bodies; morphology of intracytoplasmic filaments; melanosome-producing and melanosome-containing cells in tumours; myofilaments in striated muscle; and pathological variations in size, shape, and numbers of microbodies. The intracytoplasmic and intranuclear annulate lamellae are fully covered. An in-depth account of the classification, history, and nomenclature of lysosomes are provided. The morphology and normal variations of melanosomes and anchoring fibrils are completely presented. A chapter is devoted to the endocytotic structures and cell processes. Another section focuses on the classification and nomenclature of fibrous components. The book can provide useful information to cytologists, pathologists, students, and researchers.

Human Eosinophils

Human Eosinophils Book
Author : Gianni Marone
Publisher : S Karger Ag
Release : 2000-01-01
ISBN : 9783805569743
Language : En, Es, Fr & De

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Book Description :

"This volume provides the reader with a comprehensive survey of the major aspects of human eosinophilic biology and immunology as well as the most clinically relevant aspects of eosinophil-related disorders. Expert contributions cover the ultrastructural and phenotypic characteristics of human eosinophils, and their fundamental biochemical features including receptors for IgE and chemokines. The production of cytokines and their role in the activation of eosinophils are reviewed. Furthermore, the classic eosinophil-related disorders such as hypereosinophilia, drug reactions, allergic disorders and some cardiovascular diseases are described. Each of the chapters is written by an investigator actively engaged in research on the topic under consideration. The material compiled in this volume will be of interest to all those working in allergology, immunology, biochemistry and pulmonary medicine."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved

Stress Proteins in Medicine

Stress Proteins in Medicine Book
Author : Willem Van Eden,Douglas B. Young
Publisher : CRC Press
Release : 2020-11-25
ISBN : 1000148513
Language : En, Es, Fr & De

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Book Description :

Provides a thorough overview of current knowledge of stress proteins in both normal and disease physiology and evaluates the potential for developing novel diagnostic, prophylactic, and therapeutic approaches to control human disease based on the latest stress-protein research.

Cumulated Index Medicus

Cumulated Index Medicus Book
Author : Anonim
Publisher : Unknown
Release : 1989
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cumulated Index Medicus book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Peroxidases in Chemistry and Biology

Peroxidases in Chemistry and Biology Book
Author : Johannes Everse,Matthew B. Grisham,Kathleen E. Everse
Publisher : CRC Press
Release : 1990-11-20
ISBN : 9780849369636
Language : En, Es, Fr & De

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Book Description :

The Peroxidases in Chemistry and Biology series provides up-to-date information on a wide range of developments in the field of Peroxidases, methods and applications. This is Volume 1 originally published in 1990.

Diagnostic Ultrastructural Pathology

Diagnostic Ultrastructural Pathology Book
Author : Ann M. Dvorak,Rita A. Monahan-Earley
Publisher : CRC Press
Release : 1992-04-01
ISBN : 9780849344046
Language : En, Es, Fr & De

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Book Description :

This problem-based guide illustrates key reasoning processes that physicians use to resolve individual clinical problems through the use of electron microscopy. Its format will facilitate learning the case approach for diagnostic ultrastructural pathology using clinical-ultrastructural-pathogenic correlation. A total of 51 cases and a procedural guide for the ultrastructural pathology laboratory are included. The cases were selected according to one of the following four principles: 1) classic cases that were diagnosed readily by light microscopy to facilitate the electron microscopic diagnosis of less "classic" cases; 2) diagnostic cases, those cases for which ultrastructural analysis was essential for the diagnosis; 3) supportive cases, which are those cases where either the light or the electron microscopic diagnosis is supportive and confirmatory to the other; and 4) new facts cases, which are those that establish new knowledge regarding the pathogenesis of disease using electron microscopy as the investigative modality. The 51 cases are grouped anatomically in eight major categories. Separate indices for presenting symptoms, differential diagnostic groups, ultrastructural pathology criteria, and final diagnostic categories are provided, as well. This guide will be useful to physicians and students of medicine, structure, and disease. It also makes an ideal operational guide and text for support staff training.

Diagnostic Ultrastructural Pathology Three Volume Set

Diagnostic Ultrastructural Pathology  Three Volume Set Book
Author : Ann M. Dvorak,Rita A. Monahan-Earley
Publisher : CRC Press
Release : 1995-07-01
ISBN : 9780849394980
Language : En, Es, Fr & De

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Book Description :

Download Diagnostic Ultrastructural Pathology Three Volume Set book written by Ann M. Dvorak,Rita A. Monahan-Earley, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Exotic Animal Hematology and Cytology

Exotic Animal Hematology and Cytology Book
Author : Terry Campbell
Publisher : John Wiley & Sons
Release : 2015-05-04
ISBN : 1118611276
Language : En, Es, Fr & De

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Book Description :

Exotic Animal Hematology and Cytology, Fourth Edition updates the most comprehensive reference available on exotic animal hematology and cytology of all major species. Acts as both an atlas and a text, offering high-quality photographs and step-by-step descriptions of techniques associated with preparing and interpreting hematology and cytology samples Presents complete information on hematology and cytology in a wide range of exotic species, including small mammals, birds, reptiles, amphibians, and fish Includes more than 700 high-quality color photographs, now with sizing bars Takes a new disease-based structure for improved ease of use Provides straightforward step-by-step descriptions of sample preparation and interpretation

Immunology E Book

Immunology E Book Book
Author : David Male,Victoria Male,R. Stokes Peebles, Jr.
Publisher : Elsevier Health Sciences
Release : 2020-02-19
ISBN : 0702078468
Language : En, Es, Fr & De

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Book Description :

Covering all the basic and clinical concepts you need to know for your coursework and USMLEs, Immunology, 9th Edition, offers a well-illustrated, carefully structured approach to this complex and fast-changing field. Carefully edited and authored by experts in both teaching and research, it provides cutting-edge, consistent coverage that links the laboratory and clinical practice. A user-friendly, color-coded format, including key concept boxes, explanatory diagrams, and nearly 200 photos to help you visually grasp and retain challenging concepts. Explains the building blocks of the immune system - cells, organs, and major receptor molecules - as well as initiation and actions of the immune response, especially in a clinical context. Includes extensive updates to clinical information, including recent clinical approaches in cancer immunology, transplantation, autoimmunity, hypersensitivity, and more. Features a reorganized format that presents immunology in the order in which is typically taught and learned, better integrating basic and clinical immunology. Covers new topics such as innate lymphoid cells, antibody-based therapies and antibody engineering, innate immunity and its components, the genetics of immunologically-based diseases and personalized medicine, and immunotherapeutic agents for the treatment of cancer. Provides Critical Thinking boxes, chapter-opening summaries, and case-based and USMLE-style questions that provide effective review and quick practice for exams – plus more learning opportunities online, including USMLE-style questions and clinical cases.

Veterinary Hematology and Clinical Chemistry

Veterinary Hematology and Clinical Chemistry Book
Author : Mary Anna Thrall,Glade Weiser,Robin W. Allison,Terry W. Campbell
Publisher : John Wiley & Sons
Release : 2012-07-02
ISBN : 1118378407
Language : En, Es, Fr & De

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Book Description :

Veterinary Hematology and Clinical Chemistry Veterinary Hematology and Clinical Chemistry Veterinary Hematology and Clinical Chemistry, Second Edition is a well-illustrated, user-friendly reference on veterinary laboratory diagnostic techniques and interpretation. Covering both hematology and chemistry for a wide range of species, including birds, reptiles, amphibians, and fish, the book provides an overview of these critical veterinary skills. This second edition includes many revisions and additions, including new chapters on molecular diagnostics of hematologic malignancies and lipid pathology, updates to reflect advances in diagnostic instrumentation and capabilities, significant revisions to the data interpretation chapter to provide introductory guidance, and current information on immunodiagnostics and laboratory diagnostics of renal, endocrine, and calcium metabolic pathologies. Beginning with the basic principles of laboratory testing and diagnosis, the book moves into in-depth information on hematology and chemistry of common domestic and non-domestic species. Clinical case presentations, supplying case data and offering narrative discussions to promote skills, have been expanded and incorporated into the body of the book. Packed with useful information for veterinary students, technicians, pathologists, and researchers, Veterinary Hematology and Clinical Chemistry is an essential addition to any veterinary library. KEY FEATURES Clear, concise guide to veterinary laboratory diagnostic techniques and interpretation Covers hematology and chemistry for a wide range of species, including valuable information on birds, reptiles, amphibians, and fish Encompasses both basic principles and more in-depth explanations of laboratory testing and diagnosis Adds new chapters on molecular diagnostics of hematologic malignancies and lipid pathology, as well as revised information throughout to reflect advances in the field Offers 74 case studies to promote skills in laboratory data interpretation and diagnosis Includes access to a companion website offering review questions in PowerPoint at www.wiley.com/go/thrall RELATED TITLES Veterinary Hematology: Atlas of Common Domestic and Non-domestic Species, Second Edition By William J. Reagan, Armando R. Irizarry Rovira, and Dennis B. DeNicola 9780813828091 Schalm???s Veterinary Hematology, Sixth Edition Edited by Douglas J. Weiss and K. Jane Wardrop 9780813817989 Duncan and Prasse???s Veterinary Laboratory Medicine: Clinical Pathology, Fifth Edition Edited by Kenneth S. Latimer 9780813820149

Ultrastructure Macromolecules and Evolution

Ultrastructure  Macromolecules  and Evolution Book
Author : Lawrence S. Dillon
Publisher : Springer Science & Business Media
Release : 2013-11-11
ISBN : 1461331471
Language : En, Es, Fr & De

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Book Description :

Thus far in the history of biology, two, and only two, fundamental principles have come to light that pervade and unify the entire science-the cell theory and the concept of evolution. While it is true that recently opened fields of inves tigation have given rise to several generalizations of wide impact, such as the universality of DNA and the energetic dynamics of ecology, closer inspection reveals them to be part and parcel of either of the first two mentioned. Because in the final analysis energy can act upon an organism solely at the cellular level, its effects may be perceived basically to represent one facet of cell me tabolism. Similarly, because the DNA theory centers upon the means by which cells build proteins and reproduce themselves, it too proves to be only one more, even though an exciting, aspect of the cell theory. In fact, if the matter is given closer scrutiny, evolution itself can be viewed as being a fundamental portion of the cell concept, for its effects arise only as a consequence of changes in the cell's genetic apparatus accumulating over geological time. Or, if one wishes, the diametrically opposite standpoint may be taken. For, if current concepts of the origin of life hold any validity, the evolution of precellular organisms from the primordial biochemicals must have proceeded over many eons of time prior to the advent of even the most primitive cell.

Journal of Submicroscopic Cytology

Journal of Submicroscopic Cytology Book
Author : Anonim
Publisher : Unknown
Release : 1985
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Journal of Submicroscopic Cytology book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.