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Enzyme Nanoparticles

Enzyme Nanoparticles Book
Author : Chandra S. Pundir
Publisher : William Andrew
Release : 2015-05-16
ISBN : 0323389295
Language : En, Es, Fr & De

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Book Description :

This book is the first book in English on nanotechnology and nanomaterials integrating with enzymatic systems, with a focus on nanoparticles and biological applications. It covers comprehensively the relevant topics to understand the development of enzyme nanoparticles as it relates to the complicated structures of enzyme nanoparticles and their functionalization and immobilization on to various supports. The preparation of enzyme nanoparticles, their kinetic properties and applications after immobilization of the immobilized enzyme nanoparticles is described. The use of colour images in all formats of the book will improve the understanding of the topics covered. The book offers an integration of Enzymology and Nanotechnology and provides the latest information on preparation of enzyme nanoparticles, their characterization, their functionalization and immobilization on to various supports and thereafter their kinetic properties and applications in various industries with special reference to Biosensor Technology. Focus on enzyme nanotechnology, given the wide appeal of enzymes for diagnostics, therapy and biocatalysis Provision of a general background to the topic, but also a detailed description of synthesis, preparation and applications

Armored Enzyme Nanoparticles for Remediation of Subsurface Contaminants

Armored Enzyme Nanoparticles for Remediation of Subsurface Contaminants Book
Author : Anonim
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The remediation of subsurface contaminants is a critical problem for the Department of Energy, other government agencies, and our nation. Severe contamination of soil and groundwater exists at several DOE sites due to various methods of intentional and unintentional release. Given the difficulties involved in conventional removal or separation processes, it is vital to develop methods to transform contaminants and contaminated earth/water to reduce risks to human health and the environment. Transformation of the contaminants themselves may involve conversion to other immobile species that do not migrate into well water or surface waters, as is proposed for metals and radionuclides; or degradation to harmless molecules, as is desired for organic contaminants. Transformation of contaminated earth (as opposed to the contaminants themselves) may entail reductions in volume or release of bound contaminants for remediation. Research at Rensselaer focused on the development of haloalkane dehalogenase as a critical enzyme in the dehalogenation of contaminated materials (ultimately trichloroethylene and related pollutants). A combination of bioinformatic investigation and experimental work was performed. The bioinformatics was focused on identifying a range of dehalogenase enzymes that could be obtained from the known proteomes of major microorganisms. This work identified several candidate enzymes that could be obtained through relatively straightforward gene cloning and expression approaches. The experimental work focused on the isolation of haloalkane dehalogenase from a Xanthobacter species followed by incorporating the enzyme into silicates to form biocatalytic silicates. These are the precursors of SENs. At the conclusion of the study, dehalogenase was incorporated into SENs, although the loading was low. This work supported a single Ph. D. student (Ms. Philippa Reeder) for two years. The project ended prior to her being able to perform substantive bioinformatics efforts that would identify more promising dehalogenase enzymes. The SEN synthesis, however, was demonstrated to be partially successful with dehalogenases. Further work would provide optimized dehalogenases in SENs for use in pollution remission.

Nanoarmoring of Enzymes with Carbon Nanotubes and Magnetic Nanoparticles

Nanoarmoring of Enzymes with Carbon Nanotubes and Magnetic Nanoparticles Book
Author : Anonim
Publisher : Academic Press
Release : 2020-01-16
ISBN : 0128202076
Language : En, Es, Fr & De

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Book Description :

Nanoarchitectures Built with Carbon Nanotubes and Magnetic Nanoparticles, Volume 630, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. New chapters in this volume include updates from well-known, established leaders. Contains the authority of authors who are leaders in their field Provides a comprehensive source on new methods and research in enzymology

Bioprospecting of Enzymes in Industry Healthcare and Sustainable Environment

Bioprospecting of Enzymes in Industry  Healthcare and Sustainable Environment Book
Author : Hrudayanath Thatoi,Sonali Mohapatra,Swagat Kumar Das
Publisher : Springer Nature
Release : 2021-01-23
ISBN : 9813341955
Language : En, Es, Fr & De

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Book Description :

The rapid urbanization and industrialization of developing countries across the globe have necessitated for substantial resource utilization and development in the areas of Healthcare, Environment, and Renewable energy. In this context ,this resourceful book serves as a definitive source of information for the recent developments in application of microbial enzymes in various sectors. It covers applications in fermentation processes and their products, extraction and utilisation of enzymes from various sources and their application in health and biomass conversion for production of value added products. Different chapters discuss various areas of bioprospecting in enzyme technology, and describe why these are the mainstays for industrial production of value added products. The rich compilation of the cutting-edge advances and applications of the modern industrial based techniques hold feasible solutions for a range of current issues in enzyme technology. This book will be of particular interest for scientists, academicians, technical resource persons, engineers and members of industry. Undergraduate and graduate students pursuing courses in the area of industrial biotechnology will find the information in the book valuable. General readers having interest towards biofuels, enzyme technology, fermented food and value added products, phytochemicals and phytopharmaceutical products will also find the book appealing. Readers will discover modern concepts of enzymatic bioprocess technology for production of therapeutics and industrial value added products.

New and Future Developments in Catalysis

New and Future Developments in Catalysis Book
Author : Rute André,Filipe Natálio,Wolfgang Tremel
Publisher : Elsevier Inc. Chapters
Release : 2013-07-13
ISBN : 0128081554
Language : En, Es, Fr & De

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Book Description :

Download New and Future Developments in Catalysis book written by Rute André,Filipe Natálio,Wolfgang Tremel, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biocatalysis and Nanotechnology

Biocatalysis and Nanotechnology Book
Author : Peter Grunwald
Publisher : CRC Press
Release : 2017-10-25
ISBN : 1351767542
Language : En, Es, Fr & De

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Book Description :

Nanobiocatalysis has rapidly developed into a subarea of enzyme biotechnology. It combines the advances in nanotechnology that have generated nanoscale materials of different sizes, shapes, and physicochemical properties, and the excellent characteristics of biocatalysts into an innovative technology. This book provides an overview of the various relations between nanotechnology and biocatalysis. It discusses the fabrication and application of nanomaterials for the immobilization of enzymes used in the sustainable production of goods and chemicals. Nanosupports have several advantages compared with bulk solid materials because of their high surface area, which results in a significantly reduced mass transfer limitation and comparatively high enzyme loading. These characteristics are also of great use for applications in the fields of enzymatic biosensors, biofuel cells, bioelectronics, and photoelectrochemical analyte detection, where conductive nanomaterials improve the rate of electron transfer. The book also presents an overview of nanotoxicology and covers nanostructured enzyme catalysis in organic solvents and its potential application for biodiesel production, probing of enzymatic activity, and identification of enzyme functions of inorganic nanoparticles as enzyme mimics.

Armored Enzyme Nanoparticles for Remediation of Subsurface

Armored Enzyme Nanoparticles for Remediation of Subsurface Book
Author : Jay W. Grate
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The remediation of subsurface contaminants is a critical problem for the Department of Energy, other government agencies, and our nation. Severe contamination of soil and groundwater exists at several DOE sites due to various methods of intentional and unintentional release. Given the difficulties involved in conventional removal or separation processes, it is vital to develop methods to transform contaminants and contaminated earth/water to reduce risks to human health and the environment. Transformation of the contaminants themselves may involve conversion to other immobile species that do not migrate into well water or surface waters, as is proposed for metals and radionuclides; or degradation to harmless molecules, as is desired for organic contaminants. Transformation of contaminated earth (as opposed to the contaminants themselves) may entail reductions in volume or release of bound contaminants for remediation.

Biocatalysis and Nanotechnology

Biocatalysis and Nanotechnology Book
Author : Peter Grunwald
Publisher : CRC Press
Release : 2017-10-25
ISBN : 1351767550
Language : En, Es, Fr & De

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Book Description :

Nanobiocatalysis has rapidly developed into a subarea of enzyme biotechnology. It combines the advances in nanotechnology that have generated nanoscale materials of different sizes, shapes, and physicochemical properties, and the excellent characteristics of biocatalysts into an innovative technology. This book provides an overview of the various relations between nanotechnology and biocatalysis. It discusses the fabrication and application of nanomaterials for the immobilization of enzymes used in the sustainable production of goods and chemicals. Nanosupports have several advantages compared with bulk solid materials because of their high surface area, which results in a significantly reduced mass transfer limitation and comparatively high enzyme loading. These characteristics are also of great use for applications in the fields of enzymatic biosensors, biofuel cells, bioelectronics, and photoelectrochemical analyte detection, where conductive nanomaterials improve the rate of electron transfer. The book also presents an overview of nanotoxicology and covers nanostructured enzyme catalysis in organic solvents and its potential application for biodiesel production, probing of enzymatic activity, and identification of enzyme functions of inorganic nanoparticles as enzyme mimics.

Enzymatic Fuel Cells

Enzymatic Fuel Cells Book
Author : Inamuddin,Mohammad Faraz Ahmer,,Mohd Imran Ahamed,Abdullah M. Asiri
Publisher : Materials Research Forum LLC
Release : 2019-02-16
ISBN : 1644900068
Language : En, Es, Fr & De

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Book Description :

Enzymatic biofuel cells, in contrast to conventional energy systems, use enzymes as catalysts for the conversion of chemical energy into electrical energy. These enzymes can also catalyze fuels such as sucrose, fructose and glucose. In addition to their use as catalysts, they are biocompatible in nature. Due to this fact, enzymatic biofuel cells have many interesting applications, such as implantable gadgets (biosensors, pacemakers, catheters, defibrillators, insulin pumps, self-controlled artificial muscles etc.). The book presents various aspects of biofuel cells including fuel cell electrochemistry, use of enzyme and enzyme immobilization techniques, use of materials such as mesoporous materials, graphene composites, conducting polymer composites and applications of biofuel cells.

Nanotechnology for Water Treatment and Purification

Nanotechnology for Water Treatment and Purification Book
Author : Anming Hu,Allen Apblett
Publisher : Springer
Release : 2014-07-04
ISBN : 3319065785
Language : En, Es, Fr & De

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Book Description :

This book describes the latest progress in the application of nanotechnology for water treatment and purification. Leaders in the field present both the fundamental science and a comprehensive overview of the diverse range of tools and technologies that have been developed in this critical area. Expert chapters present the unique physicochemical and surface properties of nanoparticles and the advantages that these provide for engineering applications that ensure a supply of safe drinking water for our growing population. Application areas include generating fresh water from seawater, preventing contamination of the environment and creating effective and efficient methods for remediation of polluted waters. The chapter authors are leading world-wide experts in the field with either academic or industrial experience, ensuring that this comprehensive volume presents the state-of-the-art in the integration of nanotechnology with water treatment and purification.

Metal Nanoparticles in Microbiology

Metal Nanoparticles in Microbiology Book
Author : Mahendra Rai,Nelson Duran
Publisher : Springer Science & Business Media
Release : 2011-04-02
ISBN : 9783642183126
Language : En, Es, Fr & De

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Book Description :

Following an introduction to biogenic metal nanoparticles, this book presents how they can be biosynthesized using bacteria, fungi and yeast, as well as their potential applications in biomedicine. It is shown that the synthesis of nanoparticles using microbes is eco-friendly and results in reproducible metal nanoparticles of well-defined sizes, shapes and structures. This biotechnological approach based on the process of biomineralization exploits the effectiveness and flexibility of biological systems. Chapters include practical protocols for microbial synthesis of nanoparticles and microbial screening methods for isolating a specific nanoparticle producer as well as reviews on process optimization, industrial scale production, biomolecule-nanoparticle interactions, magnetosomes, silver nanoparticles and their numerous applications in medicine, and the application of gold nanoparticles in developing sensitive biosensors.

Green Materials for Sustainable Water Remediation and Treatment

Green Materials for Sustainable Water Remediation and Treatment Book
Author : Anuradha Mishra,James H Clark
Publisher : Royal Society of Chemistry
Release : 2013-09-06
ISBN : 184973500X
Language : En, Es, Fr & De

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Book Description :

Inadequate access to clean water afflicts people throughout the world, and in developing countries any solution to this challenge must be achieved at a low cost and low energy demand. At the same time, the use of chemicals, and subsequent environmental impact must also be reduced. Green and sustainable water remediation is a rapidly growing field of interest to governments and corporations alike, with considerable input from academics, environmental consultants and public interest groups. This book presents a focused set of articles covering a range of topics in the field, examining not only the adoption of natural products for water remediation, but also the synthesis of new materials and emerging clean technologies. Contributors from across the globe (including some "on the ground" in the developing world) present a comprehensive digest in the form of review-style articles highlighting the current thinking and direction in the field. Interested stakeholders from all sectors will find this book invaluable, and postgraduate students of chemical engineering or environmental science will benefit from the real-world applications presented.

Nanotechnology for Bioenergy and Biofuel Production

Nanotechnology for Bioenergy and Biofuel Production Book
Author : Mahendra Rai,Silvio Silvério da Silva
Publisher : Springer
Release : 2016-12-19
ISBN : 3319454595
Language : En, Es, Fr & De

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Book Description :

A unique feature of this book is its focus on nanotechnological solutions for the production of bioenergy and biofuels. Coverage includes topics such as nanobiotechnology, microalgae, biofuel cells, biomass pretreatment, and biomass conversion. An international team of experts also addresses the need to precisely characterize nanoparticles and the role of catalysts. The range of topics addressed, together with a chapter on risk management, make this book a highly useful resource for a broad readership including physicists, chemists, microbiologists, biotechnologists, food technologists, agricultural engineers, and nanotechnologists.

Enzymes

Enzymes Book
Author : Selim Kermasha,Michael N.A. Eskin
Publisher : Academic Press
Release : 2020-11-27
ISBN : 0128005076
Language : En, Es, Fr & De

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Book Description :

Enzymes: Novel Biotechnological Approaches for the Food Industry provides an in-depth background of the most up-to-date scientific research and information related to food biotechnology and offers a wide spectrum of biological applications. This book addresses novel biotechnological approaches for the use of enzymes in the food industry to help readers understand the potential uses of biological applications to advance research. This is an essential resource to researchers and both undergraduate and graduate students in the biotechnological industries. Provides fundamental and rigorous scientific information on enzymes Illustrates enzymes as tools to achieve value and quality to a product, either in vitro or in vivo Presents the most updated knowledge in the area of food biotechnology Demonstrates novel horizons and potential for the use of enzymes in industrial applications

Carbonic Anhydrase Mechanism Regulation Links to Disease and Industrial Applications

Carbonic Anhydrase  Mechanism  Regulation  Links to Disease  and Industrial Applications Book
Author : Susan C. Frost,Robert McKenna
Publisher : Springer Science & Business Media
Release : 2013-10-22
ISBN : 9400773595
Language : En, Es, Fr & De

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Book Description :

The study of carbonic anhydrase has spanned multiple generations of scientists. Carbonic anhydrase was first discovered in 1932 by Meldrum and Roughton. Inhibition by sulfanilamide was shown in 1940 by Mann and Keilin. Even Hans Krebs contributed to early studies with a paper in 1948 showing the relationship of 25 different sulfonamides to CA inhibition. It was he who pointed out the importance of both the charged and uncharged character of these compounds for physiological experiments. The field of study that focuses on carbonic anhydrase (CA) has exploded in recent years with the identification of new families and isoforms. The CAs are metalloenzymes which are comprised of 5 structurally different families: the alpha, beta, gamma, and delta, and epsilon classes. The alpha class is found primarily in animals with several isoforms associated with human disease. The beta CAs are expressed primarily in plants and are the most divergent. The gamma CAs are the most ancient. These are structurally related to the beta CAs, but have a mechanism more similar to the alpha CAs. The delta CAs are found in marine algae and diflagellates. The epsilon class is found in prokaryotes in which it is part of the carboxysome shell perhaps supplying RuBisCO with CO2 for carbon fixation. With the excitement surrounding the discovery of disease-related CAs, scientists have redoubled their efforts to better understand structure-function relationships, to design high affinity, isotype-specific inhibitors, and to delineate signaling systems that play regulatory roles over expression and activity. We have designed the book to cover basic information of mechanism, structure, and function of the CA families. The authors included in this book bring to light the newest data with regard to the role of CA in physiology and pathology, across phylums, and in unique environmental niches.

Nanomaterials for Biocatalysis

Nanomaterials for Biocatalysis Book
Author : Guillermo R Castro,Ashok Kumar,Tuan Anh Nguyen,Xianghui Qi,Ghulam Yasin
Publisher : Elsevier
Release : 2021-10-15
ISBN : 0128244372
Language : En, Es, Fr & De

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Book Description :

Nanomaterials for Biocatalysis explains the fundamental design concepts and emerging applications of nanoscale biocatalysts, such as bioconversions, bioelectronics, biosensors, biocomputing and therapeutic applications. Nano-biocatalysts refers to the incorporation of enzymes into nanomaterials. These enzyme-enhanced nanocarriers have many advantages, including low mass transfer limitation, high enzyme capacity, better stabilization, and the formation of single-enzyme nanoparticles. Smart nanocontainers have been developed for the smart release of their embedded active substances. These smart releases can be obtained by using smart coatings as their outer nanoshells. In addition, these nanocontainers could protect the enzymes from chemical or metabolic alterations on their delivering pathways towards the target. This is an important reference source for materials scientists and chemical engineers who want to know more about how nanomaterials are being used for biocatalysis applications. Explains the major fabrication techniques and applications of nanobiocatalysts Shows how nanobiocatalysts are used in a variety of environmental and biomedical sectors Assesses the major challenges associated with the widespread manufacture of nanobiocatalysts

Application of Nanotechnology in Water Research

Application of Nanotechnology in Water Research Book
Author : Ajay Kumar Mishra
Publisher : John Wiley & Sons
Release : 2014-06-23
ISBN : 1118496302
Language : En, Es, Fr & De

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Book Description :

Details the water research applications of nanotechnology in various areas including environmental science, remediation, membranes, nanomaterials, and water treatment At the nano size, materials often take on unique and sometimes unexpected properties that result in them being ‘tuned’ to build faster, lighter, stronger, and more efficient devices and systems, as well as creating new classes of materials. In water research, nanotechnology is applied to develop more cost-effective and high-performance water treatment systems, as well as to provide instant and continuous ways to monitor water quality. This volume presents an array of cutting-edge nanotechnology research in water applications including treatment, remediation, sensing, and pollution prevention. Nanotechnology applications for waste water research have significant impact in maintaining the long-term quality, availability, and viability of water. Regardless of the origin, such as municipal or industrial waste water, its remediation utilizing nanotechnology can not only be recycled and desalinized, but it can simultaneously detect biological and chemical contamination. Application of Nanotechnology in Water Research describes a broad area of nanotechnology and water research where membrane processes (nanofiltration, ultrafiltration, reverse osmosis, and nanoreactive membranes) are considered key components of advanced water purification and desalination technologies that remove, reduce, or neutralize water contaminants that threaten human health and/or ecosystem productivity and integrity. Various nanoparticles and nanomaterials that could be used in water remediation (zeolites, carbon nanotubes, self-assembled monolayer on mesoporous supports, biopolymers, single-enzyme nanoparticles, zero-valent iron nanoparticles, bimetallic iron nanoparticles, and nanoscale semiconductor photocatalysts) are discussed. The book also covers water-borne infectious diseases as well as water-borne pathogens, microbes, and toxicity approach.

Enzyme Packaging Within Q Coat Protein Nanoparticles

Enzyme Packaging Within Q   Coat Protein Nanoparticles Book
Author : Jason David Fiedler
Publisher : Unknown
Release : 2012
ISBN : 9781303073137
Language : En, Es, Fr & De

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Book Description :

Nanotechnology is the study and use of materials with nanometer length scales. This unique size range presents a challenge for the production of well-defined assemblies. It is too big to create from standard chemistry techniques and too small for top-down engineering methods. We take the approach of using natural nanomaterials to create complex assemblies for a wide range of potential applications. Here we report progress with a protein nanoparticle derived from the Qß bacteriophage coat protein. This protein cage naturally binds RNA and we exploit this to package and confine functional proteins within the interior of the shell. In an effort to determine the capabilities of this RNA-packaging technology, we packaged an array of different cargo-enzymes within the protein nanoparticle. Further, we explored different variables that influence the packaging mechanism of some of these proteins to give the researcher some control over how many are loaded into each particle. These studies have also identified features of the technology that were not previously appreciated. The enzymes inside the nanoparticle are functional and comparisons with free enzymes highlight important effects that packaging has on each particular proteins. In general, the nanoparticle protects the packaged enzymes from inactivation due to non-specific proteases, adsorption, and long-term storage. In order to use this technology to deliver therapeutic enzymes to a site of action, I combined the enzyme-packaging and ligand-display techniques, developed in the lab previously. This produced nanoparticles that could be used as potential therapeutics, but the non-specific binding of the protein nanoparticle slowed progress in vitro. Finally, we manipulated the coat protein gene sequence to create self-assembling nanoparticles with different properties. Approximately half of these manipulations resulted in the loss of the ability of the coat protein to self-assemble, and the remainder had varying degrees of impact on the nanoparticle. One residue proved to be very important to the assembly mechanism and certain changes prompted the mutant coat protein to self-assemble into small aberrant structures. These were structurally investigated and may prove to be very helpful for the production of future functional materials.

Bio Nanoparticles

Bio Nanoparticles Book
Author : Om V. Singh
Publisher : John Wiley & Sons
Release : 2015-03-30
ISBN : 1118677668
Language : En, Es, Fr & De

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Book Description :

Nanoparticles are the building blocks for nanotechnology; they are better built, long lasting, cleaner, safer, and smarter products for use across industries, including communications, medicine, transportation, agriculture and other industries. Controlled size, shape, composition, crystallinity, and structure-dependent properties govern the unique properties of nanotechnology. Bio-Nanoparticles: Biosynthesis and Sustainable Biotechnological Implications explores both the basics of and advancements in nanoparticle biosynthesis. The text introduces the reader to a variety of microorganisms able to synthesize nanoparticles, provides an overview of the methodologies applied to biosynthesize nanoparticles for medical and commercial use, and gives an overview of regulations governing their use. Authored by leaders in the field, Bio-Nanoparticles: Biosynthesis and Sustainable Biotechnological Implications bridges the gap between biology and technology, and is an invaluable resource for students and researchers alike.

Nanotechnology and Human Health

Nanotechnology and Human Health Book
Author : Ineke Malsch,Claude Emond
Publisher : CRC Press
Release : 2013-08-13
ISBN : 0849381444
Language : En, Es, Fr & De

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Book Description :

Addressing medium- and long-term expectations for human health, this book reviews current scientific and technical developments in nanotechnology for biomedical, agrofood, and environmental applications. This collection of perspectives on the ethical, legal, and societal implications of bionanotechnology provides unique insight into contemporary technological developments. Readers with a technical background will benefit from the overview of the state-of-the-art research in their field, while readers with a social science background will benefit from the discussion of realistic prospects of nanotechnology. The text also includes a glossary as well as extensive end-of-chapter references.