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Environmental Metabolomics

Environmental Metabolomics Book
Author : Diana Alvarez-Munoz,Marinella Farre
Publisher : Elsevier
Release : 2020-05-19
ISBN : 0128181974
Language : En, Es, Fr & De

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Book Description :

Environmental Metabolomics Applications in Field and Laboratory Studies: From the Exposome to the Metabolome presents an overview of the current state of aquatic environments and problems caused by human pressure and daily life. The presence of contaminants in nature and their effects are evaluated, along with recommendations for preservation. This book not only shows readers how to implement techniques, it also guides them through the process. As metabolomics becomes a more routine technique for environmental studies and future perspectives, a guide for validation and globalization of current approaches is needed. Presents relevant and reliable information on the use of different analytical techniques for establishing the environmental metabolomics of polluted systems Includes a critical review of each central topic in every chapter, together with a bibliography and future trends Provides, for the first time, a global opinion and guide for achieving standardized results

Marine Environmental Metabolomics

Marine Environmental Metabolomics Book
Author : Francisco Javier Toledo
Publisher : Unknown
Release : 2016
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Marine environmental metabolomics studies the interactions of marine organisms with their environment using metabolomics to characterise these interactions. There are many advantages in using this method to study interactions between organisms and the environment and to assess the function and health of organisms at the molecular level. In fact, metabolomics is finding an increasing number of applications in the marine sciences. These range from understanding the response of organisms to abiotic pressure to researching the response of organisms to other biota. These interactions can be studied at different levels, from individuals to populations for more traditional eco-physiological or ecological studies. Marine organisms have developed a high diversity of chemical defences to avoid predators and parasites. This study therefore highlights the complexity of chemical interactions in the marine environment. The research methods include 1H- and 13C-NMR spectroscopy, mass spectrometry, analytical and preparative chromatography, and a multitude of bio-assays.

Applied Environmental Metabolomics

Applied Environmental Metabolomics Book
Author : David J. Beale,Katie E. Hillyer,Andrew C. Warden,Oliver A.H. Jones
Publisher : Academic Press
Release : 2021-06-01
ISBN : 0128164611
Language : En, Es, Fr & De

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Book Description :

Environmental Metabolomics: Approaches, Challenges and Future Perspectives brings together contributions from global experts who have helped to define and develop the exciting and rapid advances that are taking place in the field of environmental metabolomics. This book is invaluable for expert users as it demonstrates not only the best practice in experimental design, but also provides an overview of state-of-the-art instrumentation and the in-depth analysis (for instance small molecule IDs and limits of detections) one can expect to get by using various sampling, chromatographic and mass spectrometric techniques. Common experimental and technical pitfalls are also highlighted, providing unique insights into the world of environmental metabolomics that help practicing scientists avoid repeating similar costly mistakes and steer them efficiently towards the generation of high-quality data and high-impact publications. Highlights overarching principles and considerations for researchers to leverage when planning, conducting and evaluating environmental metabolomics research Provides real world case study applications of multiple environmental metabolomics techniques Integrates metabolomics standard initiatives into case study examples, demonstrating value in evaluating data Encompasses standard operating protocols for metabolomics to help new entrants to the field set up experiments and useful data

Ecometabolomics

Ecometabolomics Book
Author : Sumira Jan,Parvaiz Ahmad
Publisher : Academic Press
Release : 2019-03-10
ISBN : 012814873X
Language : En, Es, Fr & De

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Book Description :

Ecometabolomics: Metabolic Fluxes versus Environmental Stoichiometry focuses on the interaction between plants—particularly plants that have vigorous secondary metabolites—and the environment. The book offers a comprehensive overview of the responses of the metabolome of organisms to biotic and abiotic environmental changes. It includes an introduction to metabolomics, summaries of metabolomic techniques and applications, studies of stress in plants, and insights into challenges. This is a must-have reference for plant biologists, plant biochemists, plant ecologists and phytochemists researching the interface between plants and the environment using metabolomics. Provides an in-depth overview of the basics of the discipline, including non-targeted analysis and quantification of plant metabolites Outlines the applications of various analytical techniques in comprehending the total metabolome of the organism Covers both NMR and MS-based approaches

Environmental Metabolomics Investigation of the Effects of Chiral Pharmaceuticals and Environmental Pollutants on Microorganisms

Environmental Metabolomics Investigation of the Effects of Chiral Pharmaceuticals and Environmental Pollutants on Microorganisms Book
Author : Sarah Emma Wharfe,Roy Goodacre (Supervisor.),University of Manchester. School of Chemistry
Publisher : Unknown
Release : 2010
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Environmental Metabolomics Investigation of the Effects of Chiral Pharmaceuticals and Environmental Pollutants on Microorganisms book written by Sarah Emma Wharfe,Roy Goodacre (Supervisor.),University of Manchester. School of Chemistry, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Microbial Metabolomics

Microbial Metabolomics Book
Author : David J. Beale,Konstantinos A. Kouremenos,Enzo A. Palombo
Publisher : Springer
Release : 2016-12-05
ISBN : 3319463268
Language : En, Es, Fr & De

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Book Description :

This book brings together contributions from global experts who have helped to facilitate the exciting and rapid advances that are taking place in microbial metabolomics. The main application of this field is in clinical and veterinary microbiology, but there is a great potential to apply metabolomics to help to better understand complex biological systems that are dominated by multiple-species microbial populations exposed to changing growth and nutritional conditions. In particular, environmental (e.g., water, soil), food (e.g., microbial spoilage, food pathogens), and agricultural and industrial applications are seen as developing areas for microbial metabolomics. As such, the book includes contributions with clinical, environmental, and industrial perspectives.

Metabolomics

Metabolomics Book
Author : Jeevan Prasain
Publisher : BoD – Books on Demand
Release : 2016-12-28
ISBN : 9535128531
Language : En, Es, Fr & De

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Book Description :

Metabolomics: Fundamentals and Applications authoritatively presents the basic principles and applications of metabolomics. Topics covered in this book range from the analysis of metabolites from different biological sources and their data processing and statistical analysis. This book serves as a basic guide for a wide range of audiences from less familiar with metabolomics techniques to more experienced researchers seeking to understand complex biological systems from the systems biology approach.

Variation Within Arabidopsis Thaliana Ecotypic Responses to Environmental Change

Variation Within Arabidopsis Thaliana Ecotypic Responses to Environmental Change Book
Author : Christopher Paul Timothy Peters
Publisher : Unknown
Release : 2012
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Global average atmospheric CO2 concentrations are predicted to double before the end of this century. This increase has been predicted to raise global average temperatures, which in turn will increase atmospheric humidity. How plants will respond to these changes is an area of intense study. The variation within ecotypic responses of Arabidopsis thaliana to these environmental variables (C02, temperature and humidity) is explored in this thesis using a combination of morphological and novel environmental metabolomics techniques. This study utilises ecotypes of Arabidopsis thaliana originating from a range of altitudes and geographical locations to elucidate altitude-mediated variation In response to changes In environmental conditions. Morphological investigation shows that stomatal conductance is regulated by an interchangeable mechanism of stomatal density and stomatal aperture over a range of CO2 treatments and that elevated temperature or humidity can disrupt this mechanism. Furthermore, these characteristics of stomatal responses of Arabidopsis thaliana are shown to be independent of ecotypic altitude of origin. Environmental metabolomic analysis demonstrated clear separation between ecotypic rnetabolite fingerprints as well as showing correlations between ecotype altitude of origin and specific plant primary and secondary metabolites; providing novel elucidation of biochemical pathways involved in responses to environmental perturbation.

NMR Spectroscopy

NMR Spectroscopy Book
Author : Myrna J. Simpson,Andre J. Simpson
Publisher : John Wiley & Sons
Release : 2014-06-12
ISBN : 111861643X
Language : En, Es, Fr & De

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Book Description :

The challenges faced by environmental scientists today are vast,complex, and multi-faceted. For instance, predicting the fateof an environmental pollutant or understanding ecosystem responsesto climate change, necessitate a firm understanding of molecularstructure and dynamics of environmental media as well as thecomponents that exist and interact within this media. Furthermore, linking information obtained at the molecular-scale toecosystem-level processes is a major pursuit of modernenvironmental research. As such, NMR spectroscopy and itsscalability from the molecular-scale to the macroscopic-scale, isfacilitating rapid growth in environmental science. In addition,the versatility of NMR spectroscopy has resulted in the developmentand implementation of different types of NMR techniques to examinethe structure of various types of environmental samples, living andnon-living, as well as the study of critical environmentalprocesses. This comprehensive handbook is a collection of chapters thatspan from methods to how NMR is used in environmental research togain insight into various ecosystem properties. It is organized into three parts: Part A focuses on methods used in environmental NMRwhich span from solution-state to magnetic resonanceimaging. Part B emphasizes how NMR spectroscopy plays anessential role in understanding various types of environmentalcomponents and related processes, including different forms oforganic matter found in soil, water, and air as well as how NMR isused to probe the fate of water, organic pollutants, and metals inthe environment. Part C focuses on the growing field of environmentalmetabolomics which uses NMR as its main discoveryplatform. This volume highlights the immense potential of NMR spectroscopyto expand our fundamental understanding of environmental processesand how it will continue to do so well into the future. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of MagneticResonance) publishes a wide range of online articles on allaspects of magnetic resonance in physics, chemistry, biology andmedicine. The existence of this large number of articles, writtenby experts in various fields, is enabling the publication of aseries of eMagRes Handbooks on specific areas of NMR and MRI. Thechapters of each of these handbooks will comprise a carefullychosen selection of eMagRes articles. In consultation with theeMagRes Editorial Board, the eMagRes handbooks arecoherently planned in advance by specially-selected Editors, andnew articles are written to give appropriate complete coverage. Thehandbooks are intended to be of value and interest to researchstudents, postdoctoral fellows and other researchers learning aboutthe scientific area in question and undertaking relevantexperiments, whether in academia or industry. Have the content of this handbook and the complete content ofeMagRes at your fingertips! Visit: ahref="http://www.wileyonlinelibrary.com/ref/eMagRes"www.wileyonlinelibrary.com/ref/eMagRes/a

Metabolomics

Metabolomics Book
Author : Justin S. Knapp,William L. Cabrera
Publisher : Nova Science Pub Incorporated
Release : 2011
ISBN : 9781616680060
Language : En, Es, Fr & De

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Book Description :

Metabolomics is the logical progression of the study of genes, transcripts and proteins. Nutrients, gut microbial metabolites and other bioactive food constituents interact with the body at system, organ, cellular and molecular levels, and effect the expression of genome at several levels, and subsequently, the production of metabolites. This book presents an overview of nutrigenomics and metabolomics tools, and their perspective in livestock health and production. In addition, this book describes how lists of masses (molecular ions) and mass unit bins of interest are searched within online databases for compound identification, the extra biochemical data required for metabolite confirmation, how data are visualised and what the putative and protein sequences are associated with observed metabolic changes. Moreover, environmental metabolomics is the application of metabolomics to the investigation of both free-living organisms directly obtained from the natural environment or laboratory conditions. This book outlines some of the advances made in areas of plant environmental metabolomics. The applications of microbial metagenomics, the use of genomics techniques to the study of communities of directly in their diverse natural environments, are explored as well. Other chapters examine the abnormalities in metabolism of cancer cells, which could play a strategic role in tumour initiation and behaviour.

The Functional Significance of Genetic Diversity in Plants

The Functional Significance of Genetic Diversity in Plants Book
Author : Katie Jayne Field
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Functional Significance of Genetic Diversity in Plants book written by Katie Jayne Field, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Environmental Metabolomics as a Novel Tool for Assessment of Freshwater Bivalve Health

Environmental Metabolomics as a Novel Tool for Assessment of Freshwater Bivalve Health Book
Author : Jennifer Lee Hurley-Sanders
Publisher : Unknown
Release : 2014
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Environmental Metabolomics as a Novel Tool for Assessment of Freshwater Bivalve Health book written by Jennifer Lee Hurley-Sanders, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

An Environmental Metabolomics Study of the Effect of Abiotic Substances on Pseudomonas Putida by Employing Analytical Techniques

An Environmental Metabolomics Study of the Effect of Abiotic Substances on Pseudomonas Putida by Employing Analytical Techniques Book
Author : Ali Abdu H. Sayqal
Publisher : Unknown
Release : 2016
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download An Environmental Metabolomics Study of the Effect of Abiotic Substances on Pseudomonas Putida by Employing Analytical Techniques book written by Ali Abdu H. Sayqal, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Environmental Problems in Marine Biology

Environmental Problems in Marine Biology Book
Author : Tamara Garcia Barrera,Jose Luis Gomez Ariza
Publisher : CRC Press
Release : 2017-07-12
ISBN : 1351645404
Language : En, Es, Fr & De

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Book Description :

Marine environment can be affected by several pollutants such as the presence of elements and their chemical species, pharmaceuticals, nanoparticles and other emerging contaminants. Environmental monitoring can be assessed by genomics, proteomics (i.e. redox proteomics), chemical speciation analysis and metallomics, metabolomics as well as other advanced strategies. The present book is a useful methodological tool for researchers and specialists in the field of analytical chemistry, environmental sciences, biochemistry, genomics and toxicology. The book includes for the first time the methodological aspects and applications related to chemical speciation and –omics strategies applied to marine environment.

Artemia Franciscana as a Model for Stress in Saltwater Lakes

Artemia Franciscana as a Model for Stress in Saltwater Lakes Book
Author : Melissa Ann Morgan
Publisher : Unknown
Release : 2018
ISBN : 9780438639973
Language : En, Es, Fr & De

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Book Description :

Due to rising salinity of freshwater systems and the lack of information about contaminants in saltwater lakes, there is a need for new methods to identify stressors and their effects in saline environments. We propose the use of the saltwater aquatic crustacean, Artemia franciscana, as a model organism for environmental metabolomics analysis of stressors for saltwater ecosystems. Artemia is an ideal indicator species because it is well-studied, have short life-cycles, and are robust. Their hemolymph has a high concentration of small molecule metabolites in an open circulatory system that is susceptible to environmental conditions and amenable to metabolomics analysis. Environmental metabolomics methods use analytical techniques, such as nuclear magnetic resonance (NMR) and mass spectrometry (MS), with chemometric analysis to characterize the interactions of an organism with its environment. When exposed to a stressor, these methods are used to identify biomarkers of exposure and assess the biochemical pathways that are impacted. The small molecule metabolite profile of Artemia was characterized using 1D and 2D NMR and GC-MS and 43 metabolites were identified. Environmental metabolomics methods were developed using untargeted 1H NMR and GC-MS analysis coupled with high-content imaging to assess Artemia exposed to established and emerging stressors, which included temperature stress, Roundup® herbicide, and tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) flame retardant. Targeted metabolomics analysis with LC-MS/MS was introduced to study the effects of perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA), 118 metabolites were identified with this method. Multivariate and univariate statistical analysis was used to identify biomarkers of exposure for each stressor and pathway analysis identified biochemical pathways that were likely affected. Although each stressor had a unique effect, it was determined that sugars, which are important for energy pathways such as glycolysis, and osmolytes, such as betaine and gadusol, play an important role in Artemia stress response.

Environmental Metabolomics Biomonitoring of Pharmaceuticals and Personal Care Products in Wild Eastern Oysters crassostrea Virginica in Georgia USA Estuaries

Environmental Metabolomics   Biomonitoring of Pharmaceuticals and Personal Care Products in Wild Eastern Oysters  crassostrea Virginica  in Georgia  USA Estuaries Book
Author : David William Brew
Publisher : Unknown
Release : 2019
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Environmental Metabolomics Biomonitoring of Pharmaceuticals and Personal Care Products in Wild Eastern Oysters crassostrea Virginica in Georgia USA Estuaries book written by David William Brew, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Microbial Metabolomics

Microbial Metabolomics Book
Author : Edward E.K. Baidoo
Publisher : Humana Press
Release : 2018-11-13
ISBN : 9781493987566
Language : En, Es, Fr & De

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Book Description :

This detailed volume includes protocols that represent the breadth of microbial metabolomics approaches to both large-scale and small-scale experiments with intention of highlighting techniques that can be used for applications ranging from environmental microbiology to human disease. Utilizing mass spectrometry as their primary measurement tool, the chapters explore microbial metabolomics, metabolism and microbial physiology, metabolite sample preparation, current analytical techniques used to profile primary and secondary metabolites and lipids, as well as establishing data analysis workflows for targeted metabolomics, untargeted metabolomics, analysis of metabolic fluxes, and genome-scale models. Written for the highly successful Methods in Molecular Biology series, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Microbial Metabolomics: Methods and Protocols serves as an ideal reference for both novice and advanced users and can be adapted to similar analytical platforms or customized to suit the needs of the researcher.

Metabolomics Identifies Metabolic Disturbances in Key Neurodevelopmental Pathways in Human Embyonic Stem Cells and Derivatives Following Exposure to Valproic Acid

Metabolomics Identifies Metabolic Disturbances in Key Neurodevelopmental Pathways in Human Embyonic Stem Cells and Derivatives Following Exposure to Valproic Acid Book
Author : Jessica A. Quam
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Metabolomics Identifies Metabolic Disturbances in Key Neurodevelopmental Pathways in Human Embyonic Stem Cells and Derivatives Following Exposure to Valproic Acid book written by Jessica A. Quam, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Understanding the Basis of Plant Population Responses to Environmental Change

Understanding the Basis of Plant Population Responses to Environmental Change Book
Author : Rachel George
Publisher : Unknown
Release : 2015
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Understanding the Basis of Plant Population Responses to Environmental Change book written by Rachel George, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.