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Environmental Factors In Neurodevelopmental And Neurodegenerative Disorders

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Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders

Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders Book
Author : Michael Aschner,Lucio G. Costa
Publisher : Academic Press
Release : 2015-07-29
ISBN : 9780128002285
Language : En, Es, Fr & De

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Book Description :

Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders presents a state-of-the-art review of the effects of environmental contaminants on the development and degeneration of the human nervous system, brought together by world-leading experts in the field. Part One describes the adverse effects that the environment can have on neurological development, and how these effects may exhibit. Specific contaminants and their possible consequences of exposure are addressed (lead, methylmercury, alcohol), as well as specific disorders and the environmental factors associated with them, such as the effect of diet on attention deficit and hyperactivity disorders. Part Two tackles neurodegenerative disorders, specifically addressing their potential neurotoxic origins, and discussing the increasing interest in the effects that early exposure may have in later life. Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders is an invaluable reference for those professionals working in the fields of toxicology, environmental health and neuroscience. Provides, for the first time, the cutting-edge theory of environmental impacts on both neurodegenerative and neurodevelopmental disorders Written by an international selection of the world's foremost experts in the field of neurotoxicology Full-colour throughout, providing accurate and illustrative examples of neurotoxic effects in action An invaluable reference for those professionals working in the fields of toxicology, environmental health, and neuroscience

Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders

Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders Book
Author : Michael Aschner,Lucio G. Costa
Publisher : Academic Press
Release : 2015-06-18
ISBN : 012800407X
Language : En, Es, Fr & De

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Book Description :

Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders presents a state-of-the-art review of the effects of environmental contaminants on the development and degeneration of the human nervous system, brought together by world-leading experts in the field. Part One describes the adverse effects that the environment can have on neurological development, and how these effects may exhibit. Specific contaminants and their possible consequences of exposure are addressed (lead, methylmercury, alcohol), as well as specific disorders and the environmental factors associated with them, such as the effect of diet on attention deficit and hyperactivity disorders. Part Two tackles neurodegenerative disorders, specifically addressing their potential neurotoxic origins, and discussing the increasing interest in the effects that early exposure may have in later life. Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders is an invaluable reference for those professionals working in the fields of toxicology, environmental health and neuroscience. Provides, for the first time, the cutting-edge theory of environmental impacts on both neurodegenerative and neurodevelopmental disorders Written by an international selection of the world’s foremost experts in the field of neurotoxicology Full-colour throughout, providing accurate and illustrative examples of neurotoxic effects in action An invaluable reference for those professionals working in the fields of toxicology, environmental health, and neuroscience

Obesogenic Environmental Conditions Affect Neurodevelopment and Neurodegeneration

Obesogenic Environmental Conditions Affect Neurodevelopment and Neurodegeneration Book
Author : Gustavo Pacheco-Lopez,Marcel Pérez-Morales,Kioko Rubi Guzman-Ramos,Johnny Davis Figueroa,Ute Krügel,Javier A. Bravo
Publisher : Frontiers Media SA
Release : 2021-09-23
ISBN : 2889713482
Language : En, Es, Fr & De

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Book Description :

Download Obesogenic Environmental Conditions Affect Neurodevelopment and Neurodegeneration book written by Gustavo Pacheco-Lopez,Marcel Pérez-Morales,Kioko Rubi Guzman-Ramos,Johnny Davis Figueroa,Ute Krügel,Javier A. Bravo, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Environmental Neuroscience

Environmental Neuroscience Book
Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Health and Medicine Division,Board on Environmental Studies and Toxicology,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
Publisher : National Academies Press
Release : 2021-01-22
ISBN : 0309683092
Language : En, Es, Fr & De

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Book Description :

Humans are potentially exposed to more than 80,000 toxic chemicals in the environment, yet their impacts on brain health and disease are not well understood. The sheer number of these chemicals has overwhelmed the ability to determine their individual toxicity, much less potential interactive effects. Early life exposures to chemicals can have permanent consequences for neurodevelopment and for neurodegeneration in later life. Toxic effects resulting from chemical exposure can interact with other risk factors such as prenatal stress, and persistence of some chemicals in the brain over time may result in cumulative toxicity. Because neurodevelopmental and neurodegenerative disorders - such as attention-deficit hyperactivity disorder and Parkinson's disease - cannot be fully explained by genetic risk factors alone, understanding the role of individual environmental chemical exposures is critical. On June 25, 2020, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders hosted a workshop to lay the foundation for future advances in environmental neuroscience. The workshop was designed to explore new opportunities to bridge the gap between what is known about the genetic contribution to brain disorders and what is known, and not known, about the contribution of environmental influences, as well as to discuss what is known about how genetic and environmental factors interact. This publication summarizes the presentation and discussion of the workshop.

Environmental Factors in Neurodegenerative Diseases

Environmental Factors in Neurodegenerative Diseases Book
Author : Anonim
Publisher : Academic Press
Release : 2017-09-19
ISBN : 0128127651
Language : En, Es, Fr & De

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Book Description :

Environmental Factors in Neurodegenerative Diseases, Volume One addresses contemporary advances in neurotoxicology, with thematic volumes providing authoritative review articles on key issues in the field. Updates in this new volume include chapters on Air pollution and neurodegenerative diseases, Mercury and Parkinson’s disease, Pesticides and PD: current evidence, Aluminum and neurodegeneration, Microglia and neurodegeneration, Dietary factors, Mitochondria in neurodegeneration, and Manganese and neurodegeneration. Edited by leading experts, volumes are designed as in-depth overviews of the latest topic developments that analyze the effect of varied chemical agents on the nervous system. It is an essential resource for researchers and graduate students alike. Includes, in one single publication, a selection of comprehensive reviews devoted to neurotoxicology Edited by high-profile, leading academics in the field, ensuring a quality publication for subscribers Aims to widen the scope for participation by international contributors, researchers and editorial board members outside North America Serves a broad audience of university faculty, researchers and students, as well as the industry, drug development companies and the government

Brain abnormalities due to genetic alterations or developmental exposure to environmental factors

Brain abnormalities due to genetic alterations or developmental exposure to environmental factors Book
Author : Kazuhiko Sawada,Atsushi Yoshiki,Shigeyoshi Saito
Publisher : Frontiers Media SA
Release : 2022-08-31
ISBN : 2889768767
Language : En, Es, Fr & De

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Book Description :

Download Brain abnormalities due to genetic alterations or developmental exposure to environmental factors book written by Kazuhiko Sawada,Atsushi Yoshiki,Shigeyoshi Saito, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Linking Environmental Exposure to Neurodevelopmental Disorders

Linking Environmental Exposure to Neurodevelopmental Disorders Book
Author : Michael Aschner,Lucio G. Costa
Publisher : Academic Press
Release : 2018-06
ISBN : 9780128155516
Language : En, Es, Fr & De

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Book Description :

Advances in Neurotoxicology, Volume Two, addresses contemporary advances in neurotoxicology, with thematic volumes providing authoritative review articles on key issues in the field. Updates in this new volume include chapters on Air pollution and neurodegenerative diseases, Mercury and Parkinson's disease, Pesticides and PD: current evidence, Aluminum and neurodegeneration, Microglia and neurodegeneration, Dietary factors, Mitochondria in neurodegeneration, and Manganese and neurodegeneration. Edited by leading experts, volumes are designed as in-depth overviews of the latest topic developments that analyze the effect of varied chemical agents on the nervous system. It is an essential resource for researchers and graduate students alike. Includes, in one single publication, a selection of comprehensive reviews devoted to neurotoxicology Edited by high-profile, leading academics in the field, ensuring a quality publication for subscribers Aims to widen the scope for participation by international contributors, researchers and editorial board members outside North America Serves a broad audience of university faculty, researchers and students, as well as the industry, drug development companies and the government

The SAGE Encyclopedia of Intellectual and Developmental Disorders

The SAGE Encyclopedia of Intellectual and Developmental Disorders Book
Author : Ellen Braaten
Publisher : SAGE Publications
Release : 2018-01-29
ISBN : 1506353304
Language : En, Es, Fr & De

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Book Description :

According to the CDC "about one in six, or about 15%, of children aged 3 through 17 years have one or more developmental disabilities," such as ADHD, autism spectrum disorders, cerebral palsy, intellectual disability, and learning disability. Intellectual disorders are characterized by significant limitations in both intellectual functioning and in adaptive behavior, which covers many everyday social and practical skills, impacting learning, reasoning, problem solving, and other cognitive processes. These disabilities originate before the age of 18 and continue across the life span. Developmental disorders are chronic disabilities that can be cognitive or physical or both. The disabilities appear before the age of 22 and are likely to progress across the lifespan. Some developmental disorders are largely physical issues, such as cerebral palsy or epilepsy. Some individuals may have a disorder that includes a physical and intellectual disability; for example, Down syndrome or fetal alcohol syndrome. Intellectual and developmental disorders are significant and growing issues that are studied across a number of disciplines. The SAGE Encyclopedia of Intellectual and Developmental Disorders is aimed at students interested in psychology, counseling, education, social work, psychiatry, health sciences, and more. This encyclopedia will provide an in-depth look at a wide range of disorders, alongside interventions, the latest research translated for an undergraduate audience, historical context, and assessment tools for higher-level students. We will take a truly interdisciplinary approach by also covering sociocultural viewpoints, policy implications, educational applications, ethical issues, and more.

McCance Huether s Pathophysiology E Book

McCance   Huether   s Pathophysiology   E Book Book
Author : Julia Rogers
Publisher : Elsevier Health Sciences
Release : 2022-08-03
ISBN : 0323789897
Language : En, Es, Fr & De

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Book Description :

Learn the what, how, and why of pathophysiology! With easy-to-read, in-depth descriptions of disease, disease etiology, and disease processes, McCance and Huether’s Pathophysiology: The Biologic Basis for Disease in Adults and Children, 9th Edition helps you understand the most important and most complex pathophysiology concepts. This updated text includes more than 1,300 full-color illustrations and photographs to make it easier to identify normal anatomy and physiology, as well as alterations of function. It’s the most comprehensive and authoritative pathophysiology text available! Unparalleled coverage of pathophysiology content makes this the most comprehensive and authoritative pathophysiology text on the market. Consistent presentation of diseases includes pathophysiology, clinical manifestations, and evaluation and treatment. Over 1,300 full-color illustrations and photographs depict the clinical manifestations of disease and disease processes ? more than in any other pathophysiology text. Algorithms and flowcharts of diseases and disorders make it easy for you to follow the sequential progression of disease processes. Lifespan content includes ten separate pediatric chapters and special sections with aging and pediatrics content. Coverage of rare diseases and epigenetics further explores genetic disease traits. Obesity and Nutritional Disorders chapter thoroughly covers these growing global concerns. Chapter summary reviews provide concise synopses of the main points of each chapter. More than 30 3D animations on the companion Evolve website bring difficult concepts to life for a new perspective on disease processes. NEW! More than 50 new or revised illustrations visually reinforce pathophysiology concepts. NEW! Emerging Science boxes highlight the most current research and clinical developments.

Organoids as Model Systems for Human Development Disease and Clinical Applications

Organoids as Model Systems for Human Development  Disease and Clinical Applications Book
Author : Eumorphia Remboutsika,Thimios Mitsiadis
Publisher : Frontiers Media SA
Release : 2021-11-23
ISBN : 2889716600
Language : En, Es, Fr & De

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Book Description :

Download Organoids as Model Systems for Human Development Disease and Clinical Applications book written by Eumorphia Remboutsika,Thimios Mitsiadis, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Clinical Handbook of Air Pollution Related Diseases

Clinical Handbook of Air Pollution Related Diseases Book
Author : Fabio Capello,Antonio Vittorino Gaddi
Publisher : Springer
Release : 2018-02-21
ISBN : 3319627317
Language : En, Es, Fr & De

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Book Description :

This book examines in detail the clinical implications of those diseases that either are primarily triggered by air pollution or represent direct consequences of air pollutants. The aim is to provide medical practitioners with practical solutions to issues in diagnosis and treatment while simultaneously furnishing other interested parties with crucial information on the field. The book introduces the concept that air pollution-related diseases constitute a new class of pathologies. A wide range of conditions mainly attributable to air pollution are discussed, covering different body systems and pollution impacts in subsets of the population. In addition to presenting state of the art overviews of clinical aspects, the book carefully examines the implications of current knowledge for social and public health strategies aimed at disease prevention and prophylaxis. The Clinical Handbook of Air Pollution-Related Diseases will greatly assist doctors and healthcare workers when dealing with the consequences of air pollution in their everyday practice and will provide researchers, industry, and policymakers with valuable facts and insights.

Neurodegenerative Diseases

Neurodegenerative Diseases Book
Author : Shamim I. Ahmad
Publisher : Springer Science & Business Media
Release : 2012-03-12
ISBN : 1461406536
Language : En, Es, Fr & De

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Book Description :

The editor of this volume, having research interests in the field of ROS production and the damage to cellular systems, has identified a number of enzymes showing ·OH scavenging activities details of which are anticipated to be published in the near future as confirmatory experiments are awaited. It is hoped that the information presented in this book on NDs will stimulate both expert and novice researchers in the field with excellent overviews of the current status of research and pointers to future research goals. Clinicians, nurses as well as families and caregivers should also benefit from the material presented in handling and treating their specialised cases. Also the insights gained should be valuable for further understanding of the diseases at molecular levels and should lead to development of new biomarkers, novel diagnostic tools and more effective therapeutic drugs to treat the clinical problems raised by these devastating diseases.

Neurodegenerative Diseases

Neurodegenerative Diseases Book
Author : Daniela Galimberti,Elio Scarpini
Publisher : Springer Science & Business
Release : 2014-04-23
ISBN : 144716380X
Language : En, Es, Fr & De

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Book Description :

This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer’s disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and additional neurodegenerative diseases. Different aspects of each disease are reviewed, including clinical issues, treatments, basic discoveries (genetics and molecular biology), and translation of basic research into biomarkers for early diagnosis. In addition, emerging data indicate that neurodegeneration seems to also be present in classically non-degenerative disorders. Therefore, a chapter about overlapping mechanisms between dementias and psychiatric disorders is included, as well as a description of the role of neurodegeneration in multiple sclerosis. Neurodegenerative Diseases is aimed at clinicians, particularly those working in academic hospitals. This multidisciplinary book will also be of interest to basic researchers in medical fields.

Molecular and Biochemical Toxicology

Molecular and Biochemical Toxicology Book
Author : Robert C. Smart,Ernest Hodgson
Publisher : John Wiley & Sons
Release : 2017-11-06
ISBN : 1119042437
Language : En, Es, Fr & De

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Book Description :

Written as an advanced text for toxicology students, this book is much more than an introduction and provides in-depth information describing the underlying mechanisms through which toxicants produce their adverse responses. • Links traditional toxicology to modern molecular techniques, important for teaching to graduate courses and professional studies • Uses a didactic approach with basic biological or theoretical background for the methodology presented • Brings together and comprehensively covers a range of dynamic aspects in biochemical and molecular toxicology • Guides student and professional toxicologists in comprehending a broad range of issues, compiled and authored by a diverse group of experts • “A good introductory textbook covering the biochemical toxicology of organic substances and the relevant methodology in some detail.... It offers good value for money and can be recommended as a textbook for appropriate courses” – BTS Newsletter review of the 4th edition

Neurodegenerative Diseases Looking Beyond the Boundaries of the Brain

Neurodegenerative Diseases  Looking Beyond the Boundaries of the Brain Book
Author : Elena Zenaro,Marietta Zille,Claudia Perez-Cruz,Gabriel Gutiérrez-Ospina
Publisher : Frontiers Media SA
Release : 2022-07-25
ISBN : 2889765997
Language : En, Es, Fr & De

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Book Description :

Download Neurodegenerative Diseases Looking Beyond the Boundaries of the Brain book written by Elena Zenaro,Marietta Zille,Claudia Perez-Cruz,Gabriel Gutiérrez-Ospina, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Brain Protection in Schizophrenia Mood and Cognitive Disorders

Brain Protection in Schizophrenia  Mood and Cognitive Disorders Book
Author : Michael S. Ritsner
Publisher : Springer Science & Business Media
Release : 2010-06-16
ISBN : 904818553X
Language : En, Es, Fr & De

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Book Description :

Neuroprotection is a novel perspective for the treatment of disorders that lead to neurodegeneration and disabilities as a result of deterioration of neurons due to apoptosis, oxidative stress, excitotoxicity, and other mechanisms. These mechanisms have implications not only for neurodegenerative disorders, but also for schizophrenia, mood and cognitive disorders. The purpose of this book is to provide an up-to-date overview of basic and clinical studies concerning the neuroprotective approach, mechanisms, and several compounds with neuroprotective properties that may contribute to more efficacious treatment of major mental health disorders. The book is divided into two sections. The first section serves as an introduction and overview of conceptual issues of the neuroprotective approach, and some neurobiological advances. Chapters in this section review definitions, perspectives, and issues that provide a conceptual base for the rest of the book. In addition, this part includes chapters in which the authors present and discuss the findings from basic studies of neurodegenerative mechanisms that are associated with the pathogenesis of major mental health disorders. The second section focuses on findings obtained from clinical trials with neuroprotective compounds, and neuromodulatory techniques. The take-home message is that principles of the neuroprotective approach may be applied to treatment of schizophrenia, mood and cognitive disorders. Contributors to this book are among the most active investigators and clinicians in the field who provide new perspectives not only clarifying ongoing controversies but also propose diverse aspects and new insights to neuroprotection. This book is intended for a broad readership, which includes a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, graduate students, and policy makers in the fields of mental health.

Reactive Oxygen Species in Biology and Human Health

Reactive Oxygen Species in Biology and Human Health Book
Author : Shamim I. Ahmad
Publisher : CRC Press
Release : 2017-12-19
ISBN : 1498735460
Language : En, Es, Fr & De

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Book Description :

Unlike other narrowly focused books, Reactive Oxygen Species in Biology and Human Health provides a comprehensive overview of ROS. It covers the current status of research and provides pointers to future research goals. Additionally, it authoritatively reviews the impact of reactive oxygen species with respect to various human diseases and discusses antioxidants and other compounds that counteract oxidative stress. Comprised of seven sections, the first section describes the introduction, detection, and production of ROS, emphasizing phenolic compounds and vitamin E for their abilities to act as antioxidants. This section also highlights the role of lipoprotein-associated oxidative stress. Section two addresses the importance of iron accumulation in the brain resulting in the development of a group of neurodegenerative disorders (NDs) and identifies several causative genes for neurodegeneration with brain iron accumulation (NBIA) associated with Parkinsonism-related disorders. The third section discusses a number of NDs, including amyotrophic lateral sclerosis (ALS), Alzheimer’s disease (AD), Huntington's disease (HD), epilepsy, and multiple sclerosis (MS). Section four addresses autoimmune diseases caused by ROS, including asthma, autoimmune liver diseases, rheumatoid arthritis, thyroid disease, primary biliary cirrhosis, and systemic lupus. Section five analyzes a number of different cancers, including lung cancer, breast cancer, and melanoma, along with possible treatment regimens. Section six discusses cardiovascular diseases (CVDs) induced by ROS, presents the ROS-associated complex biochemical processes inducing inflammation as an important cause of CVDs, and explains the roles carotenoids play in preventing CVDs. The final section addresses other human diseases induced by oxidative stress, including sickle cell disease, nonalcoholic steatohepatitis, retinopathy, fibromyalgia, chronic obstructive pulmonary disease, asthma, pulmonary hypertension, infertility, and aging of human skin.

Environmental Experience and Plasticity of the Developing Brain

Environmental Experience and Plasticity of the Developing Brain Book
Author : Alessandro Sale
Publisher : John Wiley & Sons
Release : 2016-02-04
ISBN : 111893167X
Language : En, Es, Fr & De

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Book Description :

Environmental Experience and Plasticity of the Developing Brain goes beyond the genetic basis of neurodevelopment. Chapters illuminate the external factors that can dramatically impact the brain early in life and, consequently, the eventual accomplishment of developmental milestones and the construction of adult behavior and personality. Authored and edited by leaders in this rapidly growing field, Environmental Experience and Plasticity of the Developing Brain not only surveys preexisting literature on the effects of environment versus genetics, but also discusses more recent studies on the impacts of neurodevelopment in terms of maternal stimulation, environmental enrichment and sensory deprivation. The book also includes key examples of environmental impacts on preexisting genetic syndromes leading to developmental disabilities. Focus is also given to the consequences of early adverse experience in primates, as well as neurobiological and behavioral consequences in institutionalized human children and the reversibility of such consequences. Environmental Experience and Plasticity of the Developing Brain encompasses a broad area of research in the field of developmental neurobiology and offers a unique combination of different examples of environmental factors affecting brain development and behavior.

Advances in Probiotics for Sustainable Food and Medicine

Advances in Probiotics for Sustainable Food and Medicine Book
Author : Gunjan Goel,Ashok Kumar
Publisher : Springer Nature
Release : 2020-11-25
ISBN : 9811567956
Language : En, Es, Fr & De

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Book Description :

This book focuses on probiotics as sustainable foods and medicines, discussing issues such as screening and identification of probiotics, health claims, and advances in processing technologies, as well as food safety. Based on sound scientific research, the book is a unique reference resource for food scientists interested in development of probiotic based functional foods and their marketing. It will also appeal to those working in the area of regulations regarding the use of and health claims for fermented foods, both locally and globally.

Factors Affecting Neurological Aging

Factors Affecting Neurological Aging Book
Author : Colin R. Martin,Victor R. Preedy,Rajkumar Rajendram
Publisher : Academic Press
Release : 2021-06-18
ISBN : 0128179910
Language : En, Es, Fr & De

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Book Description :

Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet is a comprehensive reference on the genetic and behavioral features associated with neurological aging and associated disorders. This book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the physiological, behavioral, molecular, and cellular features of neurological aging. Finally, this comprehensive resource examines the use of animal modeling of aging and neurological disease. Provides the most comprehensive coverage on a broad range of topics related to the neuroscience of aging Features sections on the genetic components that influence aging and diseases of aging Focuses on neurological diseases and conditions linked to aging, environmental factors and clinical recommendations Includes more than 500 illustrations and tables