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Environmental Epigenetics In Toxicology And Public Health

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Environmental Epigenetics in Toxicology and Public Health

Environmental Epigenetics in Toxicology and Public Health Book
Author : Rebecca Fry
Publisher : Academic Press
Release : 2020-10-23
ISBN : 0128199695
Language : En, Es, Fr & De

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Book Description :

Environmental Epigenetics in Toxicology and Public Health provides in-depth discussions of the suite of complex environmental factors shown to impact epigenetic components within the cell, as well as evidence that these epigenetic modifications are tied to early and later life health effects. This book offers a translational research perspective, highlighting both in vivo and human population-based evidence for ties between the environment, the epigenome, and health outcomes, with an emphasis on evidence for transgenerational effects of exposures, as well as developmental windows of susceptibility to environmentally-linked epigenetic effects. This volume in the Translational Epigenetics series aides in the development of new therapeutic options meant to reverse inappropriate epigenetic alterations, helping researchers in their efforts prevent and treat a variety of chronic diseases tied to environmental exposures. Offers a thorough discussion of the environmental factors influencing epigenetic mechanisms in early and late life, and in transgenerational inheritance Examines both animal model and human population-based research in environmental epigenetics, highlighting developmental windows of vulnerability to epigenetic modification Features contributions from international experts in the field

Environmental Epigenetics

Environmental Epigenetics Book
Author : L. Joseph Su,Tung-chin Chiang
Publisher : Springer
Release : 2015-05-18
ISBN : 1447166787
Language : En, Es, Fr & De

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Book Description :

This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Toxicoepigenetics

Toxicoepigenetics Book
Author : Shaun D. McCullough,Dana Dolinoy
Publisher : Academic Press
Release : 2018-11-02
ISBN : 0128124342
Language : En, Es, Fr & De

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Book Description :

Toxicoepigenetics: Core Principles and Applications examines the core aspects of epigenetics, including chromatin biology, DNA methylation, and non-coding RNA, as well as fundamental techniques and considerations for studying each of these mechanisms of epigenetic regulation. Although its integration into the field of toxicology is in its infancy, epigenetics have taken center stage in the study of diseases such as cancer, diabetes, and neurodegeneration. Increasing the presence of epigenetics in toxicological research allows for a more in-depth understanding of important aspects of toxicology such as the role of the environment and lifestyle influencing the individual susceptibility to these effects and the trans-generational transmission of these health effects and susceptibilities. Methods chapters are included to help improve efficacy and efficiency of protocols in both the laboratory and the classroom. Toxicoepigenetics: Core Principles and Applications is an essential book for researchers and academics using epigenetics in toxicology research and study. Introduces the fundamental principles and practices for understanding the role of the epigenome in toxicology Presents the foundation of epigenetics for toxicologists with a broad range of backgrounds Discusses the incorporation of epigenetics and epigenomics into current toxicological studies and interpretation of epigenetic data in toxicological applications

Epigenetics and Human Health

Epigenetics and Human Health Book
Author : Alexander Haslberger,Sabine Greßler
Publisher : John Wiley & Sons
Release : 2011-08-24
ISBN : 352764475X
Language : En, Es, Fr & De

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Book Description :

After first introducing the concept of epigenetics, this handbook and ready reference provides an overview of the main research on epigenetics. It adopts a multidisciplinary approach, involving molecular biology, molecular epidemiology and nutritional science, with a special focus of the book is on disease prevention and treatment. Of interest to all healthcare-related professionals as well as nutritionists, and the medical community focusing on disease prevention.

Molecular Clinical and Environmental Toxicology

Molecular  Clinical and Environmental Toxicology Book
Author : Andreas Luch
Publisher : Springer Science & Business Media
Release : 2012-06-07
ISBN : 3764383402
Language : En, Es, Fr & De

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Book Description :

Environmental Toxicology is the third volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life. By providing intriguing insights far down to the molecular level, this three-volume work covers the entire range of modern toxicology with special emphasis on recent developments and achievements. It is written for students and professionals in medicine, science, public health or engineering who are demanding reliable information on toxic or potentially harmful agents and their adverse effects on the human body.

Toxicology and Epigenetics

Toxicology and Epigenetics Book
Author : Saura C. Sahu
Publisher : John Wiley & Sons
Release : 2012-08-23
ISBN : 1118349067
Language : En, Es, Fr & De

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Book Description :

Epigenetics is the study of both heritable and non-heritablechanges in the regulation of gene activity and expression thatoccur without an alteration in the DNA sequence. Thisdynamic and rapidly developing discipline is making its impactacross the biomedical sciences, in particular in toxicology whereepigenetic differences can mean that different individuals responddifferently to the same drug or chemical. Toxicology and Epigenetics reflects the multidimensionalcharacter of this emerging area of toxicology, describingcutting-edge molecular technologies to unravel epigenetic changes,the use of in vivo and in vitro models, as well asthe potential use of toxicological epigenetics in regulatoryenvironments. An international team of experts consider theinterplay between epigenetics and toxicology in a number of areas,including environmental, nutritional, pharmacological, andcomputational toxicology, nanomaterials, proteomics andmetabolomics, and cancer research. Topics covered include: environment, epigenetics and diseases DNA methylation and toxicogenomics chromatin at the intersection of disease and therapy epigenomic actions of environmental arsenicals environment, epigenetics and cardiovascular health toxicology, epigenetics and autoimmunity ocular epigenomics: potential sites of environmental impact indevelopment and disease nuclear RNA silencing and related phenomena in animals epigenomics – impact for drug safety sciences methods of global epigenomic profiling transcriptomics: applications in epigenetic toxicology Toxicology and Epigenetics is an essential insight intothe current trends and future directions of research in thisrapidly expanding field for investigators, toxicologists, riskassessors and regulators in academia, industry and government.

Translational Toxicology and Therapeutics

Translational Toxicology and Therapeutics Book
Author : Michael D. Waters,Claude L. Hughes
Publisher : John Wiley & Sons
Release : 2017-11-10
ISBN : 1119023629
Language : En, Es, Fr & De

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Book Description :

Written by leading research scientists, this book integrates current knowledge of toxicology and human health through coverage of environmental toxicants, genetic / epigenetic mechanisms, and carcinogenicity. Provides information on lifestyle choices that can reduce cancer risk Offers a systematic approach to identify mutagenic, developmental and reproductive toxicants Helps readers develop new animal models and tests to assess toxic impacts of mutation and cancer on human health Explains specific cellular and molecular targets of known toxicants operating through genetic and epigenetic mechanisms

Environmental Toxicology

Environmental Toxicology Book
Author : Edward A. Laws
Publisher : Springer Science & Business Media
Release : 2012-12-12
ISBN : 1461457645
Language : En, Es, Fr & De

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Book Description :

Environmental Toxicology provides a detailed, comprehensive introduction to this key area of sustainability and public health research. The broad coverage includes sections on ecological risk assessment, monitoring, mechanisms, fate and transport, prevention, and correctives, as well as treatment of the health effects of solar radiation and toxicology in the ocean. The 23 state-of-the-art chapters provide a multi-disciplinary perspective on this vital area, which encompasses environmental science, biology, chemistry, and public health.

Systems Biology in Toxicology and Environmental Health

Systems Biology in Toxicology and Environmental Health Book
Author : Rebecca Fry
Publisher : Academic Press
Release : 2015-06-11
ISBN : 0128015683
Language : En, Es, Fr & De

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Book Description :

Systems Biology in Toxicology and Environmental Health uses a systems biological perspective to detail the most recent findings that link environmental exposures to human disease, providing an overview of molecular pathways that are essential for cellular survival after exposure to environmental toxicants, recent findings on gene-environment interactions influencing environmental agent-induced diseases, and the development of computational methods to predict susceptibility to environmental agents. Introductory chapters on molecular and cellular biology, toxicology and computational biology are included as well as an assessment of systems-based tools used to evaluate environmental health risks. Further topics include research on environmental toxicants relevant to human health and disease, various high-throughput technologies and computational methods, along with descriptions of the biological pathways associated with disease and the developmental origins of disease as they relate to environmental contaminants. Systems Biology in Toxicology and Environmental Health is an essential reference for undergraduate students, graduate students, and researchers looking for an introduction in the use of systems biology approaches to assess environmental exposures and their impacts on human health. Provides the first reference of its kind, demonstrating the application of systems biology in environmental health and toxicology Includes introductions to the diverse fields of molecular and cellular biology, toxicology, and computational biology Presents a foundation that helps users understand the connections between the environment and health effects, and the biological mechanisms that link them

Examining the Causal Relationship Between Genes Epigenetics and Human Health

Examining the Causal Relationship Between Genes  Epigenetics  and Human Health Book
Author : Wambuguh, Oscar J.
Publisher : IGI Global
Release : 2019-03-22
ISBN : 1522580670
Language : En, Es, Fr & De

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Book Description :

For as much as we know about DNA and gene expression, many more mysteries remain to be solved. Epigenetics and epigenomics seek to study heritable modifications in gene expression that do not involve underlying DNA sequences to further human health changes. Examining the Causal Relationship Between Genes, Epigenetics, and Human Health provides innovative research methods and applications of chemical activation or deactivation of genes without altering the original DNA sequence. While highlighting topics including gene expression, personalized medicine, and public policy, this book is ideal for researchers, geneticists, biologists, medical professionals, students, and academics seeking current research on the expanding fields of genomics, epigenomics, proteomics, pharmacogenomics, and genome-wide association studies.

Environmental Toxicology And Human Health Volume II

Environmental Toxicology And Human Health   Volume II Book
Author : Tetsuo Satoh
Publisher : EOLSS Publications
Release : 2009-03-29
ISBN : 1848262523
Language : En, Es, Fr & De

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Book Description :

Environmental Toxicology and Human Health is a component of Encyclopedia of Environmental and Ecological Sciences, Engineering and Technology Resources in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. Toxicology is the study of harmful effects of chemicals on biological systems. Humans, animals, and plants are increasingly being exposed to chemicals in the environment. The ever-increasing use of chemicals in industries has also resulted in further pollution of the environment. As toxic chemicals are widespread in the environment, there is a potential for these chemicals to cause significant damage and harmful effects on human health. The volume on Environmental Toxicology and Human Health discusses matters of great relevance to our world such as: Environmental Toxicology and Human Health; Health Effects from Exposure to Acute Levels of Industrial Chemicals; Health Effects from Exposure to Chronic Levels of Industrial Chemicals; Control Strategies; Pediatric Lead Poisoning of Residential Origin; Insecticides; Herbicides; Rodenticides; Virus-Induced Diseases; Fungus and Actinomycete-Induced Diseases; Sportfish Consumption: Socio-Cultural and Economic Aspects, Ethnicity and Effectiveness of Health Advisories; Impact of Socioeconomic Factors on Residential Indoor Air Quality and Human Health; Social Concerns for Environmental Exposures to Toxic Substances; Environmental Justice as a Component of Environmental Decision-Making; Minamata Disease in Japan; Mercury-Contaminated Grain in Iraq; Case Study of Air Pollution Episodes in Meuse Valley of Belgium, Donora of Pennsylvania, and London, U.K.; Case Study of the Bhopal Incident; Case Study of Lyme Disease; Case History: Ebola Hemorrhagic Fever in Zaire, 1995; Case Studies of Anthrax Outbreaks; Case Study of Health Effects of Cryptosporidium in Drinking Water . These two volumes are aimed at the following five major target audiences: University and College Students Educators, Professional Practitioners, Research Personnel and Policy Analysts, Managers, and Decision Makers, NGOs and GOs.

Community Engagement Organization and Development for Public Health Practice

Community Engagement  Organization  and Development for Public Health Practice Book
Author : Frederick Murphy, MSPHyg, MPIA
Publisher : Springer Publishing Company
Release : 2012-08-06
ISBN : 0826108024
Language : En, Es, Fr & De

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Book Description :

In this practical text, public health students and practitioners will learn the fundamentals of applying community engagement, organization, and development principles to create successful community public health campaigns. Emphasizing nontraditional approaches and partnerships, and the need to readjust traditional strategies, it discusses organization and development methods optimal for public health practice, including public health ethics, faith-based initiatives in community health, community assessment and measurement methods, coalition building, frameworks for developing health policy, and more. This textbook addresses work in at-risk and diverse communities, and stresses the impact of urban change on the community engagement, organization, and development process. It also discusses the methodologies and theoretical frameworks underlying successful community organizing and development. The multidisciplinary public health scholars and practitioners contributing to this work identify the skills required to both analyze the health and health care delivery challenges of underserved communities, and to understand the social, cultural, environmental, and economic determinants of health and illness. The book includes a wealth of practical approaches and case studies drawn from the authors' real-life experiences in developing successful community health campaigns. PowerPoint slides and case study exercises for each chapter accompany the text for instructor's use Key Features: Disseminates the fundamentals of applying community engagement, organization, and development principles to community public health campaigns Provides real-life examples of methods and strategies used in engaging, organizing, and empowering community residents Discusses community organization approaches and the methodologies and frameworks underlying them Emphasizes the impact of urban change on the future of community organization and development process Written and edited by contributors with a wealth of practical and academic experience

Public Health Nursing E Book

Public Health Nursing   E Book Book
Author : Marcia Stanhope,Jeanette Lancaster
Publisher : Elsevier Health Sciences
Release : 2014-07-21
ISBN : 0323294103
Language : En, Es, Fr & De

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Book Description :

Now in its 8th edition, the "gold standard" in community health nursing provides comprehensive and up-to-date content to keep you at the forefront of the ever-changing community health climate and prepare you for an effective nursing career. In addition to a solid foundation in concepts and interventions for individuals, families, and communities, you will find real-life applications of the public nurse's role, Healthy People 2020 initiatives, new chapters on forensics and genomics, plus timely coverage of disaster management and important client populations such as pregnant teens, the homeless, immigrants, and more. Evidence-Based Practice boxes illustrate how the latest research findings apply to public/community health nursing. Separate chapters on disease outbreak investigation and disaster management describe the nurse's role in surveilling public health and managing these types of threats to public health. Separate unit on the public/community health nurse's role describes the different roles and functions of the public/community health nurse within the community. Levels of Prevention boxes show how community/public health nurses deliver health care interventions at the primary, secondary, and tertiary levels of prevention. What Do You Think?, Did You Know?, and How To? boxes use practical examples and critical thinking exercises to illustrate chapter content. The Cutting Edge highlights significant issues and new approaches to community-oriented nursing practice. Practice Application provides case studies with critical thinking questions. Separate chapters on community health initiatives thoroughly describe different approaches to promoting health among populations. Appendixes offer additional resources and key information, such as screening and assessment tools and clinical practice guidelines. Linking Content to Practice boxes provide real-life applications for chapter content. NEW! Healthy People 2020 feature boxes highlight the goals and objectives for promoting health and wellness over the next decade. NEW! The Nurse in Forensics chapter focuses on the unique role of forensic nurses in public health and safety, interpersonal violence, mass violence, and disasters. NEW! Genomics in Public Health Nursing chapter includes a history of genetics and genomics and their impact on public/community health nursing care.

Trichloroethylene Toxicity and Health Risks

Trichloroethylene  Toxicity and Health Risks Book
Author : Kathleen M. Gilbert,Sarah J. Blossom
Publisher : Springer Science & Business Media
Release : 2014-02-18
ISBN : 1447163117
Language : En, Es, Fr & De

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Book Description :

A comprehensive overview of the effects of trichloroethylene toxicity caused by real-life exposure levels highlighting how exposure to trichloroethylene may contribute to the etiology of several idiopathic human diseases. Discussion will focus on different kinds of modeling and how they may be used to predict functional consequences and to dissect the contribution of different mechanistic pathways, including potential mechanisms of action for trichloroethylene toxicity in different organ systems. It will explore the role of epigenetic alterations in trichloroethylene toxicity, this provides important mechanistic information and may also provide the basis for intervention therapy. Chapters will also explain how the risks from trichloroethylene exposure may be greater in certain populations based on genetic predisposition, age of exposure and co-exposure to other chemicals With contributions from international experts in the field, Trichloroethylene: Toxicity and Health Risks is an essential resource for researchers and clinicians in toxicology, immunology, medicine and public health as well as industry and government regulatory scientists involved in safety and health protection and epidemiologists, highlighting the need for interdisciplinary cooperation in solving issues of environmental toxicity.

Toxicity of Pesticides on Health and Environment

Toxicity of Pesticides on Health and Environment Book
Author : Robin Mesnage,Gilles-Eric Seralini
Publisher : Frontiers Media SA
Release : 2018-12-07
ISBN : 2889456447
Language : En, Es, Fr & De

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Book Description :

Public policy is regularly shaken by health crises or unexpected discoveries; future directions in toxicology assessment are therefore urgently needed. Convergent evidences suggest endocrine or nervous disrupting effects of pesticides, as well as effects on wildlife and the environment. These effects are amplified by the use of surfactants and/or combinations of different active principles. The usual concepts of regulatory toxicology are challenged by endocrine, nervous or immune disruption, or epigenetic effects. Indeed, most pollutants alter cell-cell communication systems to promote chronic diseases. They may accumulate in the food chain. Mixtures effects with other pollutants may change their bioavailability and their toxicity. The lack of scientific knowledge in these matters has large costs for public health. This Research Topic focuses on the toxic effects of pesticides associated with large scale cultivation of genetically modified (GM) plants.

Modern Poisons

Modern Poisons Book
Author : Alan Kolok
Publisher : Island Press
Release : 2016-05-05
ISBN : 1610913825
Language : En, Es, Fr & De

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Book Description :

Modern Poisons bridges the gap between traditional toxicology textbooks and journal articles on cutting-edge science. This accessible book explains basic principles in plain language while illuminating the most important issues in contemporary toxicology. Kolok begins by exploring age-old precepts such as the dose-response relationship and goes on to show exactly how chemicals enter the body and elicit their toxic effect. Kolok then traces toxicology's development, from studies of endocrine-disrupting chemicals in toiletries to the emerging science on prions and epigenetics. Whether studying toxicology itself, public health, or environmental science, readers will develop a core understanding of--and curiosity about--this fast-changing field.

Pollution Abstracts

Pollution Abstracts Book
Author : N.A
Publisher :
Release : 1993
ISBN :
Language : En, Es, Fr & De

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Book Description :

Indexes material from conference proceedings and hard-to-find documents, in addition to journal articles. Over 1,000 journals are indexed and literature published from 1981 to the present is covered. Topics in pollution and its management are extensively covered from the standpoints of atmosphere, emissions, mathematical models, effects on people and animals, and environmental action. Major areas of coverage include: air pollution, marine pollution, freshwater pollution, sewage and wastewater treatment, waste management, land pollution, toxicology and health, noise, and radiation.

Early life Environmental Exposure and Disease

Early life Environmental Exposure and Disease Book
Author : Yankai Xia
Publisher : Springer Nature
Release : 2020-07-09
ISBN : 9811537976
Language : En, Es, Fr & De

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Book Description :

This book offers valuable insights into the latest concepts and findings from epidemiologic, clinical and basic studies in the burgeoning area of early-life environmental exposure and diseases. The book is divided into five parts, starting with an overview of environmental exposure measurement and evaluation, followed by a review of the effects of exposure to various substances like tobacco smoke, pesticides and metals as well as stress on offspring’s health. It then discusses the developmental origins of a range of childhood diseases that affect growth, neural development and the immune system, and highlights the importance of longitudinal studies that measure exposure at potentially sensitive time points during childhood. It also provides up-to-date evidence of the intergenerational/transgenerational effects of early-life environmental exposure, especially via genetic and epigenetic pathways. Allowing readers to gain a thorough understanding of the predominating aspects of early-life environmental exposure and diseases, the book also provides a basis for developing environmental and health policies that could have wide and long-term impacts on human health.

Cutting Edge Therapies for Autism 2011 2012

Cutting Edge Therapies for Autism 2011 2012 Book
Author : Ken Siri,Tony Lyons
Publisher : Skyhorse Publishing Inc.
Release : 2011-04
ISBN : 1616082526
Language : En, Es, Fr & De

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Book Description :

Collects the latest information on autism research, therapies, evaluations, and treatment centers.

Essentials of Environmental Public Health Science

Essentials of Environmental Public Health Science Book
Author : Naima Bradley,Henrietta Harrison,Greg Hodgson,Robie Kamanyire,Andrew Kibble,Virginia Murray
Publisher : OUP Oxford
Release : 2014-01-30
ISBN : 0191505404
Language : En, Es, Fr & De

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Book Description :

Environmental public health is an interdisciplinary approach to the study of the direct and indirect impact of exposure to environmental hazards on the public's health and wellbeing. Assessing and addressing the risks of chemical, ionising and non-ionising radiation, and noise hazards requires a sound knowledge of toxicology, environmental epidemiology, environmental science, health risk assessment, and public health principles. Essentials of Environmental Science for Public Health provides practical guidance on the technical aspects of environmental and public health investigations. Written by leaders in the field, the authors provide practical, expert advice on a range of topics from key concepts and framework for investigation to contaminated land and waste management. Case studies are used to aid learning and understand of the topics discussed. Produced by Health Protection England, Essentials of Environmental Science for Public Health offers a comprehensive and structured approach to understanding environmental public health issues and will be essential reading for all students and professionals in environmental public health.