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Engineered Nanopores For Bioanalytical Applications

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Engineered Nanopores for Bioanalytical Applications

Engineered Nanopores for Bioanalytical Applications Book
Author : Joshua B. Edel,Tim Albrecht
Publisher : William Andrew
Release : 2013-03-19
ISBN : 143773474X
Language : En, Es, Fr & De

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Book Description :

Engineered Nanopores for Bioanalytical Applications is the first book to focus primarily on practical analytical applications of nanopore development. These nanoscale analytical techniques have exciting potential because they can be used in applications such as DNA sequencing, DNA fragment sizing, DNA/protein binding, and protein/protein binding. This book provides a solid professional reference on nanopores for readers in academia, industry and engineering and biomedical fields. In addition, the book describes the instrumentation, fabrication, and experimental methods necessary to carry out nanopore-based experiments for developing new devices. Includes application case studies for detection, identification and analysis of biomolecules and related functional nanomaterials Introduces the techniques of manufacturing solid state materials with functional nanopores Explains the use of nanopores in DNA sequencing and the wider range of applications from environmental monitoring to forensics

Nanopores for Bioanalytical Applications

Nanopores for Bioanalytical Applications Book
Author : Joshua Edel,Tim Albrecht
Publisher : Royal Society of Chemistry
Release : 2012
ISBN : 184973416X
Language : En, Es, Fr & De

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Book Description :

Bioanalytical applications in nanopores are an exciting field of research which have seen rapid development over the last ten plus years. This book focuses uniquely on this research area providing an insight from the world leading experts in the area. Based on the proceedings of the 1st International Conference on Nanopores for Bioanalytical Applications (Lanzarote, 2012), it will provide a snapshot of this exciting field for the nanopores community. It describes the latest experimental and fabrication protocols necessary to carry out nanopore-based experiments and covers a wide variety of topics. These include: biological pores, solid state pores, hybrid structures, fundamental aspects, work on the underlying (bio)physics and applications in biosensing and DNA sequencing. The multidisciplinary approach to this topic makes the book suitable for readers in both academia and industry.

Confining Electrochemistry to Nanopores

Confining Electrochemistry to Nanopores Book
Author : Yi-Tao Long
Publisher : Royal Society of Chemistry
Release : 2020-10-30
ISBN : 1788012712
Language : En, Es, Fr & De

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Book Description :

The nanopore provides a highly electrochemically confined space within which single-molecule characteristics can be efficiently converted into measurable electrochemical signatures with high temporal and current resolution. Aimed at developing the concept of the electrochemical confined space in analysing single molecules, this book serves as a stepping-stone to many exciting discoveries in nanopore-based analysis of biological processes and chemical reactions in confined space. The field of nanopore sensors is growing rapidly, but there have been no new books on nanopore technology that provide an overview of the research on nanopore-based sensing until now. The book provides a good source of nanopore studies for researchers interested in and working in the general areas of electrochemistry and nanobiotechnology, especially on nanopore sensors.

Single Molecule and Single Cell Sequencing

Single Molecule and Single Cell Sequencing Book
Author : Yutaka Suzuki
Publisher : Springer
Release : 2019
ISBN : 9811360375
Language : En, Es, Fr & De

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Book Description :

This book presents an overview of the recent technologies in single molecule and single cell sequencing. These sequencing technologies are revolutionizing the way of the genomic studies and the understanding of complex biological systems. The PacBio sequencer has enabled extremely long-read sequencing and the MinION sequencer has made the sequencing possible in developing countries. New developments and technologies are constantly emerging, which will further expand sequencing applications. In parallel, single cell sequencing technologies are rapidly becoming a popular platform. This volume presents not only an updated overview of these technologies, but also of the related developments in bioinformatics. Without powerful bioinformatics software, where rapid progress is taking place, these new technologies will not realize their full potential. All the contributors to this volume have been involved in the development of these technologies and software and have also made significant progress on their applications. This book is intended to be of interest to a wide audience ranging from genome researchers to basic molecular biologists and clinicians. .

Biocompatible Graphene for Bioanalytical Applications

Biocompatible Graphene for Bioanalytical Applications Book
Author : Yuwei Hu,Fenghua Li,Dongxue Han,Li Niu
Publisher : Springer
Release : 2014-12-04
ISBN : 3662456958
Language : En, Es, Fr & De

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Book Description :

This book highlights the latest advances in the use of graphene and bio-compatible-material-decorated graphene to detect various targets (e.g. DNA, RNA, amino acids, peptides, proteins, enzymes, antigens, glucose, DA, AA, UA, ATP, NADH, gas, ions, etc.). It focuses on the specific interaction of these substances with graphene (or modified graphene) and the efficient transduction of the target recognition event into detectable signals via various techniques. Particular emphasis is given to well-designed strategies for constructing graphene-based platforms and target determination. It also covers other bio-analytical applications including cellular imaging, drug delivery and bacteria inhibition, before turning to a discussion of future challenges and prospects of graphene in bio-analytical applications. This book is intended for researchers working in the fields of analytical chemistry, nanomaterials and biomedical engineering. Li Niu is a Professor at the State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences.

Nanobiotechnology

Nanobiotechnology Book
Author : Christof M. Niemeyer,Chad A. Mirkin
Publisher : John Wiley & Sons
Release : 2004-03-12
ISBN : 9783527306589
Language : En, Es, Fr & De

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Book Description :

Nanotechnology is the key technology of the 21st century. The possibility to exploit the structures and processes of biomolecules for novel functional materials, biosensors, bioelectronics and medical applications has created the rapidly growing field of nanobiotechnology. Designed as a broad survey of the field, this book combines contributions from bioorganic and bioinorganic chemistry, molecular biology, materials science and bioanalytics to fathom the full scope of current and future developments. It is divided into four main sections: * Interphase Systems * Protein-based Nanostructures * DNA-based Nanostructures * Nanoanalytics Each chapter describes in detail currently available methods and contains numerous references to the primary literature, making this the perfect "field guide" for chemists, biologists and materials scientists who want to explore the fascinating world of nanobiotechnology.

Micro and Nano Technologies in Bioanalysis

Micro and Nano Technologies in Bioanalysis Book
Author : James W. Lee,Robert S. Foote
Publisher : Humana
Release : 2009-07-21
ISBN :
Language : En, Es, Fr & De

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Book Description :

In recent years, large-scale advances in technology have led to greater understanding of the world at the biomolecular level. In this book, expert researchers from across the globe explore the technology which makes this analysis possible.

Nanofluidics

Nanofluidics Book
Author : Joshua Benno Edel,Andrew De Mello
Publisher : Royal Society of Chemistry
Release : 2009-01-01
ISBN : 0854041478
Language : En, Es, Fr & De

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Book Description :

"In his now celebrated lecture at the 1959 meeting of the American Physical Society, Richard Feynman pondered the potential of miniaturization in the physical sciences. His vision, based on known technology, examined the limits set by physical principles and proposed a variety of new nano-tools including the concept of ""atom-by-atom"" fabrication. In the intervening decades, many of these predictions have become reality. In particular, the development and application of nanofluidics is becoming a competitive and exciting field of research. These nanoscale analytical instruments employ micromachined features and are able to manipulate fluid samples with high precision and efficiency. In a fundamental sense, chip-based analytical systems have been shown to have many advantages over their conventional (larger) analogues. Despite the growth of this field, there are surprisingly few books dedicated to nanofluidics. This book will fill the gap in the literature for a text focusing on bioanalytical applications. Written at a level accessible to experts and non-experts alike, it has the potential to become a mainstream text book for advanced nanobiotechnology courses within academic institutions."

Electrochemically Engineered Nanoporous Materials

Electrochemically Engineered Nanoporous Materials Book
Author : Dusan Losic,Abel Santos
Publisher : Springer
Release : 2015-07-18
ISBN : 3319203460
Language : En, Es, Fr & De

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Book Description :

This book provides in-depth knowledge about the fabrications, structures, properties and applications of three outstanding electrochemically engineered nanoporous materials including porous silicon, nanoporous alumina and nanotubular titania. The book integrates three major themes describing these materials. The first theme is on porous silicon reviewing the methods for preparation by electrochemical etching, properties and methods for surface functionalization relevant for biosensing applications. Biomedical applications of porous silicon are major focus, described in several chapters reviewing recent developments on bioanalysis, emerging capture probes and drug delivery. The second theme on nanoporous alumina starts with describing the concept of self-organized electrochemical process used for synthesis nanopore and nanotube structures of valve metal oxides and reviewing recent development and progress on this field. The following chapters are focused mainly on optical properties and biosensing application of nanoporous alumina providing the reader with the depth of understanding of the structure controlled optical and photonic properties and design of optical biosensing devices using different detection principles such as photoluminescence, surface plasmon resonance, reflective spectrometry, wave guiding, Raman scattering etc. The third theme is focused on nanotubular titania reviewing three key applications including photocatalysis, solar cells and drug delivery. The book represents an important resource for academics, researchers, industry professionals, post-graduate and high-level undergraduate students providing them with both an overview of the current state-of-the-art on these materials and their future developments.

Dna Nanotechnology For Bioanalysis From Hybrid Dna Nanostructures To Functional Devices

Dna Nanotechnology For Bioanalysis  From Hybrid Dna Nanostructures To Functional Devices Book
Author : Arrabito Giuseppe Domenico,Wang Liqian
Publisher : World Scientific
Release : 2017-09-25
ISBN : 1786343819
Language : En, Es, Fr & De

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Book Description :

This book is intended for non-specialists and students, presenting a unique introduction to the field of DNA nanotechnology. The primary focus is on the extraordinary advantages of specificity and sensitivity obtained by integrating DNA nanostructures in bioanalytical devices. DNA Nanotechnology for Bioanalysis provides a concise and rigorous description for the fabrication of various types of functional nanostructures by optimized software-aided high-yield synthesis. Following this is the explanation of methods to decorate these nanostructures with molecules such as proteins, metal nanoparticles or bioorganic moieties covalently bonded onto DNA via self-assemblage processes. Also provided is a concise review on non-canonical DNA structures (such as G-quadruplexes) and their targeting by small molecules for applications in pharmacology. Finally, it describes the exciting applications of DNA nanostructures in life sciences and nanomedicine, including ultraspecific molecular delivery, control of cell behavior, analysis of cell lysate and DNA-based nano-tools for super-resolution sub-cellular imaging. Contents: Nanotechnology and the Unique Role of DNA (Elisa-C Schöneweiβ, Andreas Jaekel and Barbara Saccà)DNA as Building Material at the Nanoscale: From Concepts to Software-aided Design (Wolfgang Pfeifer, Georg Homa, Giuseppe Arrabito and Barbara Saccà)DNA Sensors for the Detection of Biomolecules and Biochemical Conditions (Birgitta R Knudsen, Anni H Andersen, Magnus Stougaard, Giuseppe Arrabito, Raffaella Suriano and Yi-Ping Ho)DNA Nanostructures in Cell Biology and Medicine (Liqian Wang and Giuseppe Arrabito)Targeting G-quadruplex DNA as Potential Anti-cancer Therapy (Riccardo Bonsignore, Elisa Trippodo and Giampaolo Barone)DNA-aided Super-resolution Bioimaging (JiaJun Li, Giuseppe Arrabito and ZhaoShuai Gao) Readership: Non-specialists, undergraduate students and researchers who are interested in learning the basics of DNA nanotechnology. Keywords: DNA Nanotechnology;Nanostructures;Non-Canonical DNA Structures;G Quadruplexes;Nano-Tools;DNA Origami;DNA Aptamers;Biosensors;Drug DeliveryReview: Key Features: Constitutes a clear introduction to the field of DNA NanotechnologyWritten in an easy and catchy styleContains information of the most recent findings in the world of DNA Nanotechnology (up to 2016), optimal for researchers who want to keep updated with the latest breakthroughs in the field

Carbon Based Nanosensor Technology

Carbon Based Nanosensor Technology Book
Author : Christine Kranz
Publisher : Springer
Release : 2019-02-13
ISBN : 3030118649
Language : En, Es, Fr & De

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Book Description :

Carbon nanomaterials have gained relevance in chem/bio sensing applications owing to their unique chemical, mechanical, electrical, and thermal characteristics. Written by leading experts in the field, this book discusses selected, state-of-the art carbon-based nanomaterials, including nanodiamonds, graphene nanodots, carbon nanopores, and nanocellulose. It presents examples of chem/bio sensing applications ranging from biomedical studies, such as DNA sequencing and neurotransmitter sensing, to heavy-metal detection in environmental monitoring scenarios, and reviews the unique properties of carbon-based nanomaterials with respect to targeted sensing applications. Further, it highlights exciting future applications. Providing comprehensive information for practitioners and scientists working in the field of carbon nanomaterial technologies and their application, it is also a valuable resource for advanced students of analytical chemistry, biochemistry, electrochemistry, materials science, and micro-/nanotechnology and -sensing.

Nanotechnology in Biology and Medicine

Nanotechnology in Biology and Medicine Book
Author : Tuan Vo-Dinh
Publisher : CRC Press
Release : 2007-01-24
ISBN : 9781420004441
Language : En, Es, Fr & De

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Book Description :

The combination of biology and nanotechnology has led to a new generation of nanodevices that make it possible to characterize the chemical, mechanical, and other molecular properties, as well as discover novel phenomena and biological processes occurring at the molecular level. These advances provide science with a wide range of tools for biomedical applications in therapeutic, diagnostic, and preventive medicine. Nanotechnology in Biology and Medicine: Methods, Devices, and Applications integrates interdisciplinary research and recent advances in instrumentation and methods for applying nanotechnology to various areas in biology and medicine. Pioneers in the field describe the design and use of nanobiosensors with various analytical techniques for the detection and monitoring of specific biomolecules, including cancer cells. The text focuses on the design of novel bio-inspired materials, particularly for tissue engineering applications. Each chapter provides introductory material including a description of methods, protocols, instrumentation, and applications, as well as a collection of published data with an extensive list of references. An authoritative reference written for a broad audience, Nanotechnology in Biology and Medicine: Methods, Devices, and Applications provides a comprehensive forum that integrates interdisciplinary research to present the most recent advances in protocols, methods, instrumentation, and applications of nanotechnology in biology and medicine.

Responsive Membranes and Materials

Responsive Membranes and Materials Book
Author : D. Bhattacharyya,Thomas Schäfer,S. R. Wickramasinghe,Sylvia Daunert
Publisher : John Wiley & Sons
Release : 2012-11-26
ISBN : 1118389549
Language : En, Es, Fr & De

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Book Description :

The development of new multifunctional membranes and materials which respond to external stimuli, such as pH, temperature, light, biochemicals or magnetic or electrical signals, represents new approaches to separations, reactions, or recognitions. With multiple cooperative functions, responsive membranes and materials have applications which range from biopharmaceutical, to drug delivery systems to water treatment. This book covers recent advances in the generation and application of responsive materials and includes: Development and design of responsive membranes and materials Carbon nanotube membranes Tunable separations, reactions and nanoparticle synthesis Responsive membranes for water treatment Pore-filled membranes for drug release Biologically-inspired responsive materials and hydrogels Biomimetic polymer gels Responsive Membranes and Materials provides a cutting-edge resource for researchers and scientists in membrane science and technology, as well as specialists in separations, biomaterials, bionanotechnology, drug delivery, polymers, and functional materials.