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Endothelial Signaling In Vascular Dysfunction And Disease

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Endothelial Signaling in Vascular Dysfunction and Disease

Endothelial Signaling in Vascular Dysfunction and Disease Book
Author : Shampa Chatterjee
Publisher : Academic Press
Release : 2021-01-20
ISBN : 0128163828
Language : En, Es, Fr & De

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Book Description :

Endothelial Signaling in Vascular Dysfunction and Disease: From Bench to Bedside provides a detailed understanding of the endothelium, its activation and their link to some common clinical disorders. In addition, the book covers earlier discoveries, including those from the last and 19th centuries. It is split into five sections that cover the vascular tree as an integrative structure, the endothelium in inflammation, endothelial signaling, activation and toxicity with chemotherapy, radiation induced endothelial dysfunction and vascular disease, and therapies in combating vascular diseases. Each section is discussed with a translational approach in order to make the content truly applicable. This book is a valuable source for basic researchers, clinicians in the fields of Oncology, Cardiovascular Medicine and Radiology, and members of the biomedical field who are conducting studies related to the endothelium and vascular disease. Discusses the most relevant discoveries in endothelial biology and their link to manifestations of clinical disease Presents history and diagrams in each section to highlight the original biological discovery and its link of clinical manifestations of vascular disease Includes recent findings on the relationship between endothelial signaling, chemotherapy and radiation induced endothelial dysfunction

Ion Channels and Calcium Signaling in the Microcirculation

Ion Channels and Calcium Signaling in the Microcirculation Book
Author : William F. Jackson
Publisher : Academic Press
Release : 2020-06
ISBN : 0128200901
Language : En, Es, Fr & De

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Book Description :

Ion Channels and Calcium Signaling in the Microcirculation, Volume 85, the latest release in the Current Topics in Membranes series, highlights the latest advances in the expression and function of ion channels and calcium signaling in vascular smooth muscle and endothelial cells in resistance arteries, arterioles and capillaries, critical components of microcirculation, the business end of the cardiovascular system. Leading experts have contributed chapters, including Smooth muscle ion channels and calcium signaling in the regulation of striated muscle arteriolar tone; Endothelial KIR channels as a key component of shear stress-induced mechanotransduction; Endothelial TRPV4 channels and vasodilator reactivity, and much more. Additional sections cover cerebral capillary endothelial TRPA channels and the regulation of blood flow; Endothelial mineralocorticoid receptors and the regulation of TRPV4 function in cerebral parenchymal arterioles in hypertension; Subcellular calcium signaling and myogenic tone development in the retinal microcirculation; Microvascular KIR channels: Basis, properties and regulation by lipid and hemodynamic forces, Ion channels and calcium signaling in capillary endothelial cells; Ion channels and calcium signaling in bladder arterioles and resistance arteries, and Myoendothelial feedback and endothelial IKCa and sKCa channels.

Microvascular Research Biology and Pathology Two Volume Set

Microvascular Research  Biology and Pathology  Two Volume Set Book
Author : David Shepro
Publisher : Elsevier
Release : 2005-11-17
ISBN : 0126395101
Language : En, Es, Fr & De

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Book Description :

The microvasculature refers to the smallest blood vessels, arterial and venous, that nurture the tissues of each organ. Apart from transport, they also contribute to the systematic regulation of the body. In everyday terminology, the microcirculation is "where the action is." Microcirculation is directly involved in such disease states as Alzheimers, inflammation, tumor growth, diabetic retinopathy, and wound healing- plus cardiovascular fitness is directly related to the formation of new capillaries in large muscles. Microvascular Research is the first book devoted exclusively to this vital systemic component of the cardiovascular system and provides up to date mini-reviews of normal functions and clinical states. The contributing authors are senior scientists with international reputation in their given disciplines. This two-volume set is a broad, interdisciplinary work that encompasses basic research and clinical applications equally. * Broad coverage of both basic and clinical aspects of microvasculature research * Contains 167 chapters from over 300 international authors * Each chapter includes key figures and annotated references

Endothelial Cells in Health and Disease

Endothelial Cells in Health and Disease Book
Author : William C. Aird
Publisher : CRC Press
Release : 2005-02-28
ISBN : 1135534608
Language : En, Es, Fr & De

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Book Description :

This reference serves as the first source to gather current data from endothelial cell biologists in various disciplines to summarize recent progress in the field-providing a complete understanding of the endothelium in health and disease and demonstrating its potential as a therapeutic target.

Cumulated Index Medicus

Cumulated Index Medicus Book
Author : Anonim
Publisher : Unknown
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cumulated Index Medicus book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Endothelial Signaling in Development and Disease

Endothelial Signaling in Development and Disease Book
Author : Mirko HH Schmidt,Stefan Liebner
Publisher : Springer
Release : 2015-10-08
ISBN : 1493929070
Language : En, Es, Fr & De

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Book Description :

This book surveys healthy and diseased vascular systems in a multitude of model organisms and systems. It explores a plethora of functions, characteristics, and pathologies of the vascular system such as angiogenesis, fibroblast growth factor signaling, lymphangiogenesis, junctional signaling, the extracellular matrix, vascular permeability, leukocyte extravasation, axon guidance factors, the angiopoietin system, and chronic obstructive lung disease. Following a preface from leading researcher Dr. Holger Gerhardt, the text is divided into three sections- the first examining the development of the vascular system in a variety of contexts, the second delving into its homeostatic characteristics, and the third discussing its pathophysiologies. The sixteen chapters, which represent international clinical and research perspectives, highlight the importance of molecular and signaling pathways for translational basic science and clinical medicine. Additionally, the text explores new and exciting fields in vascular biology research. Comprehensive in both content and approach, Vascular Signaling in Health and Disease is ideal for graduate students, researchers, and clinicians interested in vascular biology, pneumology, and molecular biology.

Insulin Resistance As a Risk Factor in Visceral and Neurological Disorders

Insulin Resistance As a Risk Factor in Visceral and Neurological Disorders Book
Author : Akhlaq A. Farooqui
Publisher : Academic Press
Release : 2020-03
ISBN : 0128196033
Language : En, Es, Fr & De

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Book Description :

Insulin Resistance as a Risk Factor in Visceral and Neurological Disorders provides an overview on the risk factors for insulin resistance in visceral and neurological disorders. The book focuses on molecular mechanisms and signal transduction processes associated with the links. The comprehensive information in this monograph will not only help in the early detection of insulin resistance related visceral and neurological disorders, but also promote the discovery of new drugs which may block or delay onset in elderly patients. Understanding these processes is important not only for patients, caregivers and health professionals, but also for health policymakers who must plan for national resources.

Shear Stress induced Signaling in Vascular Endothelial Cells

Shear Stress induced Signaling in Vascular Endothelial Cells Book
Author : Song Li
Publisher : Unknown
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Shear Stress induced Signaling in Vascular Endothelial Cells book written by Song Li, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Index Medicus

Index Medicus Book
Author : Anonim
Publisher : Unknown
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Extracellular ATP and adenosine as regulators of endothelial cell function

Extracellular ATP and adenosine as regulators of endothelial cell function Book
Author : Evgenia Gerasimovskaya,Elzbieta Kaczmarek
Publisher : Springer Science & Business Media
Release : 2010-04-26
ISBN : 9789048134359
Language : En, Es, Fr & De

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Book Description :

Extracellular purines and pyrimidines (ATP, ADP, UTP and adenosine) are released into the extracellular milieu in response to a variety of stress conditions and act as important regulators of vascular homeostasis. This new book is uniquely focused on the signaling actions of extracellular purines in endothelial cells and the crucial role of extracellular purines in regulation of angiogenesis, vascular tone, cell permeability, wound healing, inflammation and cell-to-cell communication. This book examines the responses of endothelial cells, originating from various tissues (such as cornea, pancreas and uterus), to extracellular nucleotides and adenosine under physiological and pathological conditions, i.e. pregnancy, hypoxia, hypertension, inflammation and diabetes. In the book’s 12 chapters, the role of purinergic signaling in endothelium-dependent tissue perfusion, regulation of endothelial barrier function, and angiogenesis are discussed. The mechanisms of ATP release and its role in intercellular communication are also presented. In addition, the book provides the most up to date mechanisms of extracellular nucleotide metabolism by purine-converting ecto-enzymes and their contribution to purinergic signaling in endothelial cells originating from various vascular beds. This book is a valuable resource for biomedical research scientists, clinical scientists, graduate students and health science professionals interested in the mechanisms of extracellular purine function in endothelial cells under physiologic and pathologic conditions.

Science

Science Book
Author : John Michels
Publisher : Unknown
Release : 2001-06
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Science book written by John Michels, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Mechanisms of Cardiovascular Aging

Mechanisms of Cardiovascular Aging Book
Author : T. Hagen
Publisher : Elsevier Science Limited
Release : 2002-12-03
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This volume of Advances in Cell Aging and Gerontology provides a timely review on the molecular and cellular basis of cardiovascular diseases (CVD). Age itself is the leading risk factor for cardiovascular diseases, which include loss of vasomotor function, athero- and arterio-sclerosis, hypertension, congestive heart failure and stroke. Together these pathologies comprise the leading causes of permanent disability, hospitalization and death for individuals over the age of 65. Thus, there is a critical need to assess both the age-associated causes leading to CVD as well as the current state of knowledge on preventive regimens designed to slow or modulate disease progression. This book concisely summarizes the current knowledge related to the major aspects contributing to cardiovascular disfunction in the elderly as well as potential ways of maintaining or improving human cardiovascular healthspan.

Atherosclerosis XIII

Atherosclerosis XIII Book
Author : Yūji Matsuzawa,Toru Kita,Ryozo Nagai
Publisher : Elsevier Science Health Science Division
Release : 2004
ISBN : 9780444514486
Language : En, Es, Fr & De

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Book Description :

These proceedings not only summarized the scientific and technological achievements in atherosclerosis research during the 20th century but also include the latest topics for future progress and development in this new millennium, highlighting the recent advances in vascular biology, angiogenesis and atherogenesis, pathogenesis of metabolic syndrome. The articles also encompass vast range of clinical and basic research field of atherosclerosis, including epidemiology, lipoprotein metabolism, pharmacology, clinical trials, nutrition, pathogenesis, diagnosis and prevention as well as its treatment.

Autoimmunity Part B

Autoimmunity  Part B Book
Author : M. Eric Gershwin,Yehuda Shoenfeld
Publisher : Wiley-Blackwell
Release : 2007-10-08
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The incidence of autoimmune diseases is increasing worldwide, and the search for better management of these diseases and even for a cure is being pursued by scientists from many disciplines. Tools from the areas of genetics, neuroscience, cell biology, virology, and infectious disease are being applied to the problem and are yielding useful results. This is the second volume of a series of four on autoimmunity, and findings related to particular organs, organ systems, and diseases are presented. The focus in Part B is on genetics and advances in treatment. Part A presents new principles in autoimmunity and new diagnostic tools. See Parts C and D for clinical venues in autoimmunity. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member.

Circulation

Circulation Book
Author : Anonim
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Circulation book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

International Diabetes Monitor

International Diabetes Monitor Book
Author : Anonim
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download International Diabetes Monitor book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Endothelium and Cardiovascular Diseases

Endothelium and Cardiovascular Diseases Book
Author : Protasio Lemos Da Luz,Peter Libby,Francisco Rafael Martins Laurindo,Antonio Carlos Palandri Chagas
Publisher : Academic Press
Release : 2018-02-03
ISBN : 0128125519
Language : En, Es, Fr & De

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Book Description :

Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes provides an in-depth examination of the role of endothelium and endothelial dysfunction in normal vascular function, and in a broad spectrum of clinical syndromes, from atherosclerosis, to cognitive disturbances and eclampsia. The endothelium is a major participant in the pathophysiology of diseases, such as atherosclerosis, diabetes and hypertension, and these entities are responsible for the largest part of cardiovascular mortality and morbidly. Over the last decade major new discoveries and concepts involving the endothelium have come to light. This important reference collects this data in an easy to reference resource. Written by known experts, and covering all aspects of endothelial function in health and disease, this reference represents an assembly of recent knowledge that is essential to both basic investigators and clinicians. Provides a complete overview of endothelial function in health and diseases, along with an assessment of new information Includes coverage of groundbreaking areas, including the artificial LDL particle, the development of a new anti-erectile dysfunction agent, a vaccine for atherosclerosis, coronary calcification associated with red wine, and the interplay of endoplasmic reticulum/oxidative stress Explores the genetic features of endothelium and the interaction between basic knowledge and clinical syndromes

The Canadian Journal of Cardiology

The Canadian Journal of Cardiology Book
Author : Anonim
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Braunwald s Heart Disease

Braunwald s Heart Disease Book
Author : Eugene Braunwald,Peter Libby,Robert O. Bonow
Publisher : Saunders
Release : 2005
ISBN : 9780721605098
Language : En, Es, Fr & De

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Book Description :

"[A]ccompanying CD contains additional images and video clips." -- v. 2, p. xv.

The Role of Copper in Mouse Embryonic Development

The Role of Copper in Mouse Embryonic Development Book
Author : Soo Jin Yang
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Role of Copper in Mouse Embryonic Development book written by Soo Jin Yang, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.