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Endocrinology Of The Heart In Health And Disease

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Endocrinology of the Heart in Health and Disease

Endocrinology of the Heart in Health and Disease Book
Author : Jonathan C. Schisler,Charles H Lang,Monte Willis
Publisher : Academic Press
Release : 2016-10-19
ISBN : 0128031123
Language : En, Es, Fr & De

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Book Description :

Endocrinology of the Heart in Health and Disease: Integrated, Cellular, and Molecular Endocrinology of the Heart covers the traditional concepts of cardio-endocrinology, the role of the various hormone systems, both in health and disease, therapeutic implications, and other recent advances in the various fields represented. The book explores how cardiac hormones are changed in various cardiac pathologies and the recent success that has been uncovered in their therapeutic use. Additional focus is placed on how the heart responds both physiologically and pathophysiologically to a plethora of circulating hormones, reinforcing the importance of the heart as a target of numerous endocrine systems, such as the brain, renal, and adipose. Significant advances have come from basic, clinical, and translational research from a multiplicity of investigators with diverse backgrounds. The book features over 200 photomicrographs, diagrams of molecular relationships, and tables that complement and support the text. It is aimed at a wide audience, including graduate students and post-doctoral fellows in a wide array of biomedical departments and PhD programs (e.g. Pathology, Physiology, Genetics, Pharmacology, Molecular Biology, and Cell Biology) related to the endocrine and cardiovascular sciences curricula, as well as medical residents in pathology, laboratory medicine, internal medicine, and cardiology. Develops the concept of the heart as both an endocrine organ and an endocrine target, exploring the endocrine function of the heart in both health and disease Explains how the levels of several cardiac hormones are changed in various cardiac pathologies and how some hormones can be used therapeutically Offers a single resource on cardio-endocrine disease which collates and curates the wide range of advances being made in the areas of molecular biology, biochemistry, physiology, and pathology

Hormones and the Heart in Health and Disease

Hormones and the Heart in Health and Disease Book
Author : Leonard Share
Publisher : Springer Science & Business Media
Release : 1999-06-01
ISBN : 1592597084
Language : En, Es, Fr & De

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Book Description :

The maintenance of arterial blood pressure and the distribution of blood flow to the various organs of the body depends on the control of the pumping action of the heart and of the resistance of the vascular beds in the individual organs in accordance with their metabolic needs. These controls are achieved through the integrated actions of circulat ing hormones, humoral factors that are synthesized and released in the heart and blood vessels, and the autonomic nervous system. The heart, however, is not only the target for the direct and indirect actions of a number of hormones and humoral factors, it is also an endocrine organ in the traditional sense, synthesizing and secreting into the circulation chemical factors that act at distant sites. In this treatise, Hormones and the Heart in Health and Disease, we interpret "endocrinology" broadly and consider traditional hormones as well as autocoids that are secreted by the heart or that act on it. In this overview, the relevant chapters are indicated in parentheses. The discovery of atrial natriuretic peptide (ANP; atrial natriuretic factor, ANF) in the 1980s indicated that the heart does indeed function as an endocrine organ in the classic sense. ANP (Chapter I) is synthesized in the heart and secreted into the circulation for actions on the kidney, where it is a potent natriuretic agent, and on the vasculature, where it causes vasodilation. ANP can also affect myocardial contractility.

Cellular Endocrinology in Health and Disease

Cellular Endocrinology in Health and Disease Book
Author : Alfredo Ulloa-Aguirre,P. Michael Conn
Publisher : Elsevier
Release : 2014-02-12
ISBN : 0124167128
Language : En, Es, Fr & De

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Book Description :

Cellular Endocrinology in Health and Disease describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work explores and dissects the function of a number of cellular systems. Among these are those whose function was not obvious until recently, including the endocrine functions of bone and the adipose tissue. Providing content that crosses disciplines, Cellular Endocrinology in Health and Disease details how cellular endocrine function contributes to system physiology and mediates endocrine disorders. A methods section proves novel and useful approaches across research focus that will be attractive to medical students, residents, and specialists in the field of endocrinology, as well as to those interested in cellular regulation. Editors Alfredo Ulloa-Aguirre and P. Michael Conn, experts in molecular and cellular aspects of endocrinology, deliver contributions carefully selected for relevance, impact, and clarity of expression from leading field experts. Covers systemic endocrine action at the cellular level in both health and disease Delivers information on the integration of cell identity and endocrinology Incorporates recent developments in endocrinology to provide an up-to-date reference to researchers

Cardiovascular Issues in Endocrinology

Cardiovascular Issues in Endocrinology Book
Author : R. Granata,J. Isgaard
Publisher : Karger Medical and Scientific Publishers
Release : 2014-06-12
ISBN : 3318026743
Language : En, Es, Fr & De

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Book Description :

Most endocrine diseases, if not treated or controlled, have cardiovascular manifestations. Both GH deficiency and GH excess impair cardiovascular functions, e.g. in patients with acromegaly, who have a shortened life expectancy and increased mortality mostly due to cardiovascular complications in uncontrolled disease. Moreover, Cushing’s syndrome and diabetes are well known for metabolic and cardiovascular manifestations, as well as hypo- and hyperthyroidism. Both adipose tissue and the heart have been increasingly recognized as organs with partially endocrine functions, which produce adipokines and brain natriuretic peptide, respectively, and influence a number of cardiovascular parameters. Primary aldosteronism as a cause for secondary hypertension is still a great challenge to detect and diagnose properly; however, new important discoveries have been made regarding the genetics of this probably underestimated cause of hypertension. Written by distinguished researchers in their respective fields, this book will give both researchers and clinicians an excellent update on all these topics, as well as provide insight into the use of hormones as treatment tools in more controversial areas.

Diabetes in Cardiovascular Disease A Companion to Braunwald s Heart Disease E Book

Diabetes in Cardiovascular Disease  A Companion to Braunwald s Heart Disease E Book Book
Author : Darren K McGuire,Nikolaus Marx
Publisher : Elsevier Health Sciences
Release : 2014-08-27
ISBN : 0323315666
Language : En, Es, Fr & De

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Book Description :

Diabetes in Cardiovascular Disease is a current, expert resource focusing on the complex challenges of providing cardiovascular care to patients with diabetes. Designed as a companion to Braunwald’s Heart Disease, this interdisciplinary medical reference book bridges the gap between the cardiology and endocrinology communities of scientists and care providers, and highlights the emerging scientific and clinical topics that are relevant for cardiologists, diabetologists/endocrinologists, and the extended diabetes care team. Access essential coverage of basic and clinical sciences, complemented by an expanded focus on epidemiology, behavioral sciences, health policy, and disparities in health care. Take advantage of a format that follows that of the well-known and internationally recognized Braunwald’s Heart Disease. Review the best available clinical data and pragmatic recommendations for the prevention and management of cardiovascular complications of diabetes; national/societal intervention strategies to curb the growing prevalence of diabetes; and the current pathophysiological understanding of cardiovascular comorbidities in patients with diabetes. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability.

Glucose Intake and Utilization in Pre Diabetes and Diabetes

Glucose Intake and Utilization in Pre Diabetes and Diabetes Book
Author : Ronald Ross Watson,Betsy Dokken
Publisher : Elsevier
Release : 2014-11-22
ISBN : 0128005793
Language : En, Es, Fr & De

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Book Description :

This important reference, edited by Ronald Ross Watson and Betsy Dokken, collects the research needed to make the distinct connection between pre-diabetes, diabetes, and cardiovascular disease. Glucose Intake and Utilization in Pre-Diabetes and Diabetes: Implications for Cardiovascular Disease explains the mechanisms of progression from pre-diabetes to diabetes to cardiovascular disease. Since pre-diabetes and diabetes are important cardiovascular disease risk factors, and impaired glucose metabolism among cardiac patients is extremely prevalent, the importance of reviewing pre-diabetes and its involvement in CVD complications is vital as one applies food and glycemic control to slow progress to diabetes and heart disease. The book further focuses on glucose intake and utilization in diabetes, including coverage of diabetes in the development and pathology of cardiovascular disease, risks and epidemiology of cardiovascular problems promoted by diabetes, macrovascular effects and their safety in therapy of diabetics, beta cell biology and therapy of diabetes, and nutrition to modulate diabetes. Offers a complete review of cardiac health problems occurring with significant frequency in patients relative to their ability to regulate glucose Presents coverage of the role of glucose utilization, development of pre-diabetes and the ultimate development of various cardiovascular diseases Provides thorough dietary, nutrition, complementary and alternative botanical therapies for pre-diabetes and diabetes to halt the progression to cardiovascular disease

Electrical Diseases of the Heart

Electrical Diseases of the Heart Book
Author : Ihor Gussak,A. A. M. Wilde,P. A. Friedman,Charles Antzelevitch,M. J. Ackerman,W.-K. Shen
Publisher : Springer Science & Business Media
Release : 2008-09-08
ISBN : 1846288541
Language : En, Es, Fr & De

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Book Description :

This book provides a unique contemporary and succinct distillation of the current status of recently delineated electrical diseases of the heart, emphasizing their common and diverse clinical features. The latest developments in the field of experimental and clinical cardiac electrophysiology, genetics, pharmacology and interventional therapies of various clinical arrhythmogenic entities are featured and discussed in terms of recent advances in basic and clinical science. The book is divided into seven major parts. Each part consists of chapters (total of 64) dealing with related topics.

Endocrinology and Systemic Diseases

Endocrinology and Systemic Diseases Book
Author : Piero Portincasa,Gema Frühbeck,Hendrik M. Nathoe
Publisher : Springer
Release : 2020-12-28
ISBN : 9783319687285
Language : En, Es, Fr & De

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Book Description :

This work offers a comprehensive reference guide to help clinicians in the field of Internal Medicine addressing common aspects of endocrinological disorders in their daily practice. The exponential growth in our knowledge of biomedicine calls for continuous multidisciplinary approaches across specialists and disciplines. In this volume, recognized experts in each given area explore the complex mechanisms linking endocrinological disorders to abnormalities of the cardiovascular system, kidney, liver and gastrointestinal tract, autoimmune, neuro-psychiatric, rheumatic, and dermatologic diseases. Aspects connected to critically ill and elderly patients are examined as well, helping to enhance daily interactions with the most fragile populations observed in clinical medicine. The individual chapters are designed to deliver timely information while explaining pathophysiological mechanisms with the help of figures, flow-charts, and updated guidelines. The book offers a unique and valuable resource for all clinicians, residents, specialists, and physicians involved daily in the management of complex and multidisciplinary systemic diseases.

Cardiovascular Endocrinology and Metabolism

Cardiovascular Endocrinology and Metabolism Book
Author : Andrew J. Krentz,Robert J. Chilton
Publisher : Academic Press
Release : 2022-09-15
ISBN : 9780323999915
Language : En, Es, Fr & De

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Book Description :

Cardiovascular Endocrinology and Metabolism: Theory and Practice of Cardiometabolic Medicine discusses the close intersection between metabolic disorders and cardiovascular disease, covering the basic science and pathophysiology of disease and the latest research in pharmacological approaches and translational therapeutic options. This book is a valuable resource for the vascular and endocrinology clinical and research communities in need of knowledge and potential outcomes. The global increase in the prevalence of cardiometabolic disorders, and the introduction of therapeutic options for treating metabolic disease that also lower cardiovascular risk, is bringing endocrinologists and cardiologists together in a shared clinical experience. Discusses the intersection between metabolic disorders and cardiovascular diseases Provides a comprehensive understanding of the relevant pathophysiology of diseases as a basis for the evidence-based management of cardiometabolic disorders Offers a comprehensive reference, ranging from basic science and pathophysiology to clinical diagnostics and management

Insulin Like Growth Factors in Health and Disease An Issue of Endocrinology and Metabolism Clinics E Book

Insulin Like Growth Factors in Health and Disease  An Issue of Endocrinology and Metabolism Clinics   E Book Book
Author : Claire M. Perks,Jeff M.P. Holly
Publisher : Elsevier Health Sciences
Release : 2012-07-03
ISBN : 1455742775
Language : En, Es, Fr & De

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Book Description :

This issue of Endocrinology Clinics, authored by experts worldwide, provides essential updates about insulin-like growth factors (IGFs). The physiology is examined, including the latest in what we have learned from animal models as well as humans. The issue also covers IGFs and IGF system in the following: growth disorders; adipogenesis and obesity; muscle function and disease; bone; cancer; cardiac function and disease; normal and diseased kidney; peripheral nervous systems; gastrointestinal diseases; diabetes and metabolism; and IGF-1 central/degenerative diseases.

Electrical Diseases of the Heart

Electrical Diseases of the Heart Book
Author : Ihor Gussak,Charles Antzelevitch,Arthur A.M. Wilde,Brian D. Powell,Michael J. Ackerman,Win-Kuang Shen
Publisher : Springer Science & Business Media
Release : 2013-04-22
ISBN : 1447148819
Language : En, Es, Fr & De

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Book Description :

Electrical Disease of the Heart, 2nd Edition, volume 1, provides a valuable insight to the latest developments in the field of cardiac electrophysiology and clinical electrocardiology. Each chapter includes up-to-date results of studies aimed at providing an understanding of the electrical function of the heart in health and disease, established and evidence-based knowledge of clinical outcomes, areas of controversy, and future trends. This book is highly relevant to a broad audience, ranging from medical and graduate students, to clinicians and scientists.

The Thyroid and Its Diseases

The Thyroid and Its Diseases Book
Author : Markus Luster,Leonidas H. Duntas,Leonard Wartofsky
Publisher : Springer
Release : 2019-01-08
ISBN : 331972102X
Language : En, Es, Fr & De

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Book Description :

This book is an up-to-date and comprehensive guide to all the common thyroid disorders that may be seen by internists, endocrinologists, nuclear medicine physicians, and endocrine surgeons. While the fundamentals of thyroid hormone function and regulation in health and disease are well covered, the primary focus is on the clinical approach to thyroid disease, with detailed coverage of both initial diagnosis and management and the role of imaging. Because most endocrine diseases are chronic and lifelong, special emphasis is placed on long-term management and the common pitfalls that may be encountered by the clinician. The editors are internationally acknowledged leaders in the field of thyroid disease and have gathered an outstanding team of authors, all of whom are also highly expert in their respective areas, but who, equally importantly, write in a clear and lucid style. The numerous isotope scan and ultrasonographic images ensure that the book will serve as a valuable reference atlas to which the physician will return again and again.

Diabetes and Cardiovascular Disease

Diabetes and Cardiovascular Disease Book
Author : Ayman S. El-Baz,Jasjit S. Suri
Publisher : Elsevier
Release : 2021-03-23
ISBN : 0128174293
Language : En, Es, Fr & De

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Book Description :

Computer-Assisted Diagnosis: Diabetes and Cardiovascular Disease brings together multifaceted information on research and clinical applications from an academic, clinical, bioengineering and bioinformatics perspective. The editors provide a stellar, diverse list of authors to explore this interesting field. Academic researchers, bioengineers, new investigators and students interested in diabetes and heart disease need an authoritative reference to reduce the amount of time spent on source-searching so they can spend more time on actual research and clinical application. This reference accomplishes this with contributions by authors from around the world. Provides valuable information for academic clinicians, researchers, bioengineers and industry on diabetes and cardiovascular disease Discusses the impact of diabetes on cardiovascular disease Covers statistical classification techniques and risk stratification

Pathophysiology of Heart Disease

Pathophysiology of Heart Disease Book
Author : Leonard S. Lilly
Publisher : Lippincott Williams & Wilkins
Release : 2020-05-26
ISBN : 1975120604
Language : En, Es, Fr & De

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Book Description :

Enthusiastically acclaimed by medical students and faculty worldwide, this text is specifically designed to prepare students for their first encounters with patients with cardiovascular disease. Thoroughly revised by internationally recognized Harvard Medical School faculty and a team of select cardiology fellows and internal medicine residents, this seventh edition equips students with a clear, complete, and clinically relevant understanding of cardiovascular pathophysiology, setting a strong foundation for patient diagnosis and management.

Autoimmune Diseases in Endocrinology

Autoimmune Diseases in Endocrinology Book
Author : Anthony P. Weetman
Publisher : Springer Science & Business Media
Release : 2007-12-26
ISBN : 1597455172
Language : En, Es, Fr & De

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Book Description :

This is a comprehensive and novel text that examines key features that predispose individuals to autoimmune diseases. The first section details the basic mechanism of autoimmunity and examines immunogenetic and environmental factors in autoimmunity. The next section examines autoimmune thyroid disease. The third section takes a look at Type 1 diabetes mellitus. In the final section, authors explain other autoimmune endocrinopathies.

Cellular Endocrinology in Health and Disease

Cellular Endocrinology in Health and Disease Book
Author : Alfredo Ulloa-Aguirre,Ya-Xiong Tao
Publisher : Academic Press
Release : 2021-02-02
ISBN : 0128198028
Language : En, Es, Fr & De

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Book Description :

Cellular Endocrinology in Health and Disease, Second Edition, describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work explores and dissects the function of a number of cellular systems. The new edition provides an understanding of how endocrine glands function by integrating information resulting in biological effects on both local and systemic levels, also providing new information on the molecular physiopathogenesis of endocrine neoplasic cells. The new edition expands the most used chapters from the first edition and proposes a series of substitutions and additions to the table of contents. New chapters cover signaling, brown adipose tissue, hypothalamic cell models, cellular basis of insulin resistance, genetics and epigenetics of neuroendocrine tumors, and a series of chapters on endocrine-related cancer. Providing content that crosses disciplines, Cellular Endocrinology in Health and Disease, Second Edition, details how cellular endocrine function contributes to system physiology and mediates endocrine disorders. A methods section proves novel and useful approaches across research focus that will be attractive to medical students, residents, and specialists in the field of endocrinology, as well as to those interested in cellular regulation. Editors Alfredo Ulloa-Aguirre and Ya-Xiong Tao, experts in molecular and cellular aspects of endocrinology, deliver contributions carefully selected for relevance, impact, and clarity of expression from leading field experts Explores endocrine cells biology in normal and pathologic conditions Covers new aspects of endocrine cell function in distinct tissues Provides a view into the biological effect in local and systemic levels 15 new chapters covering the recent developments in the field

IGF and Nutrition in Health and Disease

IGF and Nutrition in Health and Disease Book
Author : M. Sue Houston,Jeffrey M. P. Holly,Eva L. Feldman
Publisher : Springer Science & Business Media
Release : 2004-08-04
ISBN : 1592597955
Language : En, Es, Fr & De

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Book Description :

A benchmark review on how specific nutrients or adverse nutritional states impact the components of the IGF (Insulin-like Growth Factor) system and affect human health and disease. The authors describe the fundamentals of the IGF system, explain its basic mechanisms of action, illuminate its essential role in physical development across the life span, and highlight the link between normal and abnormal cellular growth resulting in tumor formation. They also fully examine the clinical aspects of nutrition and IGF, from pre- and postnatal development through old age, in the maintenance of normal metabolism, bone, and muscle health, and their role in pathological states. Special attention is given to critical illness, diabetes, gastrointestinal diseases, kidney failure, endocrine dysfunctions, cardiovascular disease, neurological disorders, and cancer, as well as to their potential for IGF therapy.

Natriuretic Peptides in Health and Disease

Natriuretic Peptides in Health and Disease Book
Author : Willis K. Samson,Ellis Levin
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1461239605
Language : En, Es, Fr & De

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Book Description :

A comprehensive, state-of-the-art review of the biochemistry, molecular and cellular biology, pharmacology, physiology, and pathology of natriuretic peptides. Written by the foremost researchers in the field, the reviews range from describing the actions of these peptides on the kidney, adrenal gland, vasculature, and brain, to their effects on immune regulation, reproduction, and cell growth. Special attention is given to the potential involvement of these hormones in clinical pathology and to their possible therapeutic use. Especially enlightening is the first-time review of molecular understanding of key cellular signaling pathways and of the importance of the vascular smooth muscle-endothelial interface.

Promoting Cardiovascular Health in the Developing World

Promoting Cardiovascular Health in the Developing World Book
Author : Institute of Medicine,Board on Global Health,Committee on Preventing the Global Epidemic of Cardiovascular Disease: Meeting the Challenges in Developing Countries
Publisher : National Academies Press
Release : 2010-07-29
ISBN : 0309147743
Language : En, Es, Fr & De

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Book Description :

Cardiovascular disease (CVD), once thought to be confined primarily to industrialized nations, has emerged as a major health threat in developing countries. Cardiovascular disease now accounts for nearly 30 percent of deaths in low and middle income countries each year, and is accompanied by significant economic repercussions. Yet most governments, global health institutions, and development agencies have largely overlooked CVD as they have invested in health in developing countries. Recognizing the gap between the compelling evidence of the global CVD burden and the investment needed to prevent and control CVD, the National Heart, Lung, and Blood Institute (NHLBI) turned to the IOM for advice on how to catalyze change. In this report, the IOM recommends that the NHLBI, development agencies, nongovernmental organizations, and governments work toward two essential goals: creating environments that promote heart healthy lifestyle choices and help reduce the risk of chronic diseases, and building public health infrastructure and health systems with the capacity to implement programs that will effectively detect and reduce risk and manage CVD. To meet these goals, the IOM recommends several steps, including improving cooperation and collaboration; implementing effective and feasible strategies; and informing efforts through research and health surveillance. Without better efforts to promote cardiovascular health, global health as a whole will be undermined.

Practical Pediatric Endocrinology in a Limited Resource Setting

Practical Pediatric Endocrinology in a Limited Resource Setting Book
Author : Margaret Zacharin
Publisher : Academic Press
Release : 2013-04-11
ISBN : 0124079369
Language : En, Es, Fr & De

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Book Description :

Practical Pediatric Endocrinology in a Limited Resource Setting provides a guide for managing pediatric endocrine problems in a limited resource setting, together with an outline of the bases for these disorders. The book outlines a plan for coming to a likely diagnosis in situations where resources are constrained, and suggests ways to access more sophisticated technologies for diagnostic confirmation and extension of available tools. Further extending and complementing each chapter is a series of scenarios for use as teaching and learning tools. Together with a clinical question, all chapters include a suggested outline for assessment that assists readers facing similar situations in daily practice. Each scenario works through a typical series of deductive steps used to establish a working diagnosis, while considering both a differential diagnosis and reminding readers of current knowledge around the subject matter. Provides a working knowledge of pediatric endocrinology, from the viewpoint of practical application, for residents and clinicians practicing in settings with scarce material resources Features clinically based chapters, empahsising workable diagnoses and management plans in limited resource situations Includes information on Type 1 diabetes mellitus, given its increasing prevalence worldwide Describes basic research techniques and planning, intended to foster collaboration between colleagues and other centers in clinical or basic research, which can inform clinical practice and drive innovation