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Endocrine Biomarkers

Endocrine Biomarkers Book
Author : Hossein Sadrzadeh,Gregory Kline
Publisher : Elsevier
Release : 2017-09-25
ISBN : 0128034181
Language : En, Es, Fr & De

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Book Description :

Endocrine Biomarkers: Clinical Aspects and Laboratory Determination covers all the pre-analytical variables that can affect test results, both in the clinic and laboratory. Biomarkers of endocrine and bone diseases are discussed from both clinical and laboratory perspectives, and the authors elaborate on the teamwork-based app+roach between the clinician and the laboratory professional in the diagnosis and management of endocrine and bone disorders. Discussions include test utilization, laboratory measurement methods, harmonization and standardization, interpretation of results, and reference intervals. Each chapter ends with a discussion of one or two relevant cases with shared opinions from both a clinician and a clinical chemist. Each chapter also includes a summary box outlining key points and common pitfalls in the use of specific disease biomarkers and tests. Focuses on the traditional, current, and emerging clinical chemistry tests for endocrine and bone diseases, along with their application in individual clinical management Presents a brief discussion of each disorder and its respective interrelationships, along with laboratory methodologies that can be used to aid in evaluation of disorders Reviews common approaches to the measurement of the relevant hormones, with a special focus on measures that require a structured clinical testing scenario Reviews novel chemistry tests as potential means of future diagnostic tests Provides an overview of the current methodology and controversies in the concept of target lipid levels, paying particular attention to the role of clinical chemistry in helping to implement population health targets

Toxicity Biomarkers

Toxicity Biomarkers Book
Author : S. Srivastava
Publisher : IOS Press
Release : 2005
ISBN : 9781586035259
Language : En, Es, Fr & De

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Book Description :

Since the dawn of civilization, humans have feared the unknown risks associated with the use of new natural herbs or other natural medications to cure their pain, aches and illnesses. In the ancient Indian Ayurvedic Medicine which is over 4000 years old, the 'Visha (poison) Tantra (wisdom)' was developed as a discipline of medicine encompassing Toxicology and Preventive Medicines. Visha Tantra included the study of various toxic herbs and animals and their antidotes as well as the biomarkers of toxic effects. In the Visha Tantra and the practice of Ayurvedic medicine, there have been objective descriptions of the changes in colour and amount of urine, changes in the colour of nails, skin, and eyes, breathing patterns, gastrointestinal disturbances, and precautionary measures to prevent adverse effects as biomarkers of toxicity associated with the use of herbal medicines and certain foods. The adverse effects are the inevitable outcome of the environmental and industrial chemicals and pharmaceuticals; however, efforts are ongoing to prevent unexpected life-threatening toxicities and / or irreversible organ damage. The search for non-invasive biomarkers that can be objectively linked to adverse effects associated with man-made synthetic chemicals including pharmaceuticals and environmental pollutants is becoming an important priority for academics, federal agencies, pharmaceutical and industrial companies. This publication is devoted to toxicity biomarkers of target organs of toxicity and molecular epidemiology. It provides a comprehensive review of a wide spectrum of biomarkers, including molecular epidemiology biomarkers of aflatoxin and hepatitis B virus induced hepatocarcinogenesis, cytokines as the biomarkers of hepatocellular injury, drug-induced vascular injury, nephrotoxicity and reproductive toxicity biomarkers.

Use of Biomarkers for Environmental Quality Assessment

Use of Biomarkers for Environmental Quality Assessment Book
Author : Jean-Claude Amiard,Thierry Caquet,Laurent Lagadic
Publisher : CRC Press
Release : 2021-05-31
ISBN : 1000448371
Language : En, Es, Fr & De

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Book Description :

This work is primarily designed for any person or organization in charge of assessment of the quality of natural resources and of pollution prevention.

Biomarkers to Disentangle the Physiological From Pathological Brain Aging

Biomarkers to Disentangle the Physiological From Pathological Brain Aging Book
Author : F. G. Guerini,W. S. Lim,B. Arosio
Publisher : Frontiers Media SA
Release : 2020-06-22
ISBN : 2889637697
Language : En, Es, Fr & De

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Book Description :

Download Biomarkers to Disentangle the Physiological From Pathological Brain Aging book written by F. G. Guerini,W. S. Lim,B. Arosio, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Novel Targets and Biomarkers in Solid Tumors 2nd Edition

Novel Targets and Biomarkers in Solid Tumors  2nd Edition Book
Author : Dong-Hua Yang, Zhi Shi,Pascale Cohen,Huiqin Guo
Publisher : Frontiers Media SA
Release : 2020-07-16
ISBN : 2889638790
Language : En, Es, Fr & De

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Book Description :

Download Novel Targets and Biomarkers in Solid Tumors 2nd Edition book written by Dong-Hua Yang, Zhi Shi,Pascale Cohen,Huiqin Guo, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Ecological Biomarkers

Ecological Biomarkers Book
Author : Claude Amiard-Triquet,Jean-Claude Amiard,Philip S. Rainbow
Publisher : CRC Press
Release : 2016-04-19
ISBN : 1439880530
Language : En, Es, Fr & De

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Book Description :

Does a change, which affects a few biological macro-molecules, some cells, or a few individuals within a population, have any ecological significance that would allow the prediction of deleterious effects at higher levels of biological organization, namely the population, community, and ultimately the ecosystem? With contributions from experts in the field, Ecological Biomarkers: Indicators of Ecotoxicological Effects explores how biomarkers can be used to predict effects farther down the chain. It presents a synthesis of the state of the art in the methodology of biomarkers and its contribution to ecological risk assessment. This book describes the core biomarkers currently used in environmental research concerned with biological monitoring, biomarkers which correspond to the defences developed by living organisms in response to contaminants in their environment, and biomarkers that reveal biological damage resulting from contaminant stressors. It examines the efficacy of lysosomal biomarkers, immunotoxicity effects, behavioral disturbances, energy metabolism impairments, endocrine disruption measures, and genotoxicity as all indicative of probable toxic effects at higher biological levels. It is time to revisit the biological responses most ecologically relevant in the diagnosis of the health status of an aquatic environment well before it becomes unmanageable. Biomarkers provide a real possibility of delivering an easily measured marker at a simple level of biological organization that is predictably linked to a potentially ecologically significant effect at higher levels of biological organization. The text explores the latest knowledge and thinking on how to use biomarkers as tools for the assessment of environmental health and management.

Biomarkers in Toxicology

Biomarkers in Toxicology Book
Author : Ramesh C. Gupta
Publisher : Academic Press
Release : 2019-02-13
ISBN : 0128146567
Language : En, Es, Fr & De

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Book Description :

Biomarkers in Toxicology, Second Edition, is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This revised and completely updated edition includes both vertebrate and non-vertebrate species models for toxicological testing and the development of biomarkers. Divided into several key sections, this reference volume contains new chapters devoted to topics in microplastics, neuroimmunotoxicity and nutraceuticals, along with a look at the latest cutting-edge technologies used to detect biomarkers. Each chapter contains several references to current literature and important resources for further reading. Given this comprehensive treatment, this book is an essential reference for anyone interested in biomarkers across the scientific and biomedical fields. Evaluates the expansive literature, providing one resource covering all aspects of toxicology biomarkers Includes completely revised chapters, along with additional chapters on the newest developments in the field Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation, and much more

Endocrine Disruptors

Endocrine Disruptors Book
Author : Rajesh K. Naz
Publisher : CRC Press
Release : 2004-11-29
ISBN : 1420038869
Language : En, Es, Fr & De

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Book Description :

There is great concern regarding the reproductive and health hazards of endocrine disruptors. Research indicates that men are experiencing declining fertility and an increased incidence of prostate cancer, while women are dealing with increased infertility, early menopause, and breast cancer. As new research reveals the previously unknown risks of these endocrine disruptors, it is imperative to update our knowledge of these controversial chemicals. Endocrine Disruptors: Effects on Male and Female Reproductive Systems, Second Edition examines the reproductive and health hazards of endocrine-disrupting environmental chemicals from epidemiology to etiology, concluding with future directions. Divided into two sections, the first part of the book describes the effects of environmental toxicants on the female reproductive system, with an emphasis on the effects and mechanisms of their action on sex differentiation during development, fertility, and breast cancer. The second part addresses the effects of endocrine disruption on the male reproductive system, focusing on male fertility and the development of benign prostate hyperplasia (BPH) and prostate cancer. Leading authorities contribute expert analyses and up-to-date information on a topic that has become a major concern among the scientific community and the general public. This second edition supplies the most current, critical knowledge on the real risks that endocrine disruptors pose to the population.

Novel Biomarkers in the Continuum of Breast Cancer

Novel Biomarkers in the Continuum of Breast Cancer Book
Author : Vered Stearns
Publisher : Springer
Release : 2016-03-17
ISBN : 3319229095
Language : En, Es, Fr & De

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Book Description :

This volume provides a comprehensive review of established and novel biomarkers across the continuum of breast cancer. The volume covers topics related to breast cancer risk and prevention, prediction of response to today’s standard therapies, and markers capable of influencing treatment decisions in the near future. Chapter authors combine their wide-ranging expertise to review the current status of the biomarker and to offer their individual perspectives on how biomarkers may be used in future treatments and research. Breast cancer continues to be the most common malignancy diagnosed in women in the Western world. While there are multiple treatment approaches for breast cancer, today more than ever we recognize that each tumor is unique. The challenge ahead is to consider how to best use validated and novel biomarkers to select the most appropriate treatment(s) for individual patients.

The Search for Biomarkers in Psychiatry

The Search for Biomarkers in Psychiatry Book
Author : Jorge Manzanares,Maria S. Garcia-Gutierrez,Francisco Navarrete Rueda,Piotr Gałecki
Publisher : Frontiers Media SA
Release : 2021-09-14
ISBN : 2889713016
Language : En, Es, Fr & De

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Book Description :

Download The Search for Biomarkers in Psychiatry book written by Jorge Manzanares,Maria S. Garcia-Gutierrez,Francisco Navarrete Rueda,Piotr Gałecki, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Kidney Biomarkers

Kidney Biomarkers Book
Author : Seema S. Ahuja,Brian Castillo
Publisher : Academic Press
Release : 2020-07-16
ISBN : 0128163747
Language : En, Es, Fr & De

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Book Description :

Since laboratory testing and biomarkers are an integral part in the diagnosis and treatment of kidney disease, Kidney Biomarkers: Clinical Aspects and Laboratory Determination covers currently used biomarkers as well as markers that are in development. Laboratories are increasingly more involved in the follow-up confirmatory laboratory testing and this unique volume showcases the collaboration needed to solve diagnostic clinical puzzles between the laboratory and clinician. This volume provides guidance on laboratory test selection and results interpretation in patients. Sources of inaccurate results in the measurement of kidney biomarkers are discussed along with possibility of eliminating such interferences. Each chapter is organized with a uniform easy-to-follow format with insightful case examples highlighting the collaboration between clinical laboratorians and clinicians. Categorizes biomarkers into diagnostic markers, disease follow-up markers, and prognostic biomarkers Include case examples to show the collaboration between the clinical laboratorian and clinician Discusses the application of kidney biomarkers in clinical practice along with addressing laboratory aspects of kidney biomarker determination

Handbook of Therapeutic Biomarkers in Cancer

Handbook of Therapeutic Biomarkers in Cancer Book
Author : Sherry X. Yang,Janet E. Dancey
Publisher : CRC Press
Release : 2021-02-01
ISBN : 1000367533
Language : En, Es, Fr & De

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Book Description :

This book provides a comprehensive overview of the fast-evolving subject of clinical application of cancer therapeutic biomarkers. The second edition captures significant progress of cancer immunotherapy and emphasizes the genetic basis for selective cancer treatment. It covers an in-depth insight on biomarkers across a broad area of cancer research and oncology with a wealth of integrated genetic and molecular information about specific therapies by a multidisciplinary team of internationally recognized experts. Each chapter focuses on a class of targeted, immunologic, or chemotherapy agents and their companion biomarkers that predict response, benefit or resistance, and severe adverse event. The book will serve as a handbook for health professionals and scientists on the current applicable biomarkers in the management of cancer. The vision into the systemic classification and statistical consideration of therapeutic biomarkers summarized by the book editors and chapter authors will help advance precision medicine—a precisely tailored cancer treatment strategy for cancer patient care.

Molecular Diagnostics

Molecular Diagnostics Book
Author : Jan Trost Jorgensen,Henrik Winther
Publisher : Pan Stanford Publishing
Release : 2010-04-30
ISBN : 981424144X
Language : En, Es, Fr & De

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Book Description :

This unique book provides a thorough overview of developing molecular cancer diagnostic assays, which are the prerequisites for optimal solutions within personalized cancer medicine. The book takes the reader through definitions of the pharmacodiagnostic concept, historical perspectives of the early steps into molecular cancer diagnostics linked to therapy, the basis of different diagnostic molecular techniques, ongoing research, drug-diagnostic co-development, assay validation, clinical trial methodology, regulatory issues around pharmacodiagnostics and future aspects within personalized cancer medicine.

Biomarkers in Inborn Errors of Metabolism

Biomarkers in Inborn Errors of Metabolism Book
Author : Uttam Garg,Laurie D. Smith
Publisher : Elsevier
Release : 2017-06-07
ISBN : 0128029188
Language : En, Es, Fr & De

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Book Description :

Biomarkers of Inborn Errors in Metabolism: Clinical Aspects and Laboratory Determination is structured around the new reality that laboratory testing and biomarkers are an integral part in the diagnosis and treatment of inherited metabolic diseases. The book covers currently used biomarkers as well as markers that are in development. Because biomarkers used in the initial diagnosis of disease may be different than the follow-up markers, the book also covers biomarkers used in both the prognosis and treatment of inherited metabolic disorders. With the introduction of expanded new-born screening for inborn metabolic diseases, an increasing numbers of laboratories are involved in follow-up confirmatory testing. The book provides guidance on laboratory test selection and interpreting results in patients with suspected inherited metabolic diseases. The book provides comprehensive guidance on patient diagnosis and follow-up through its illustrative material on metabolic pathways, genetics and pathogenesis, treatment and prognosis of inherited metabolic diseases, along with essential information on clinical presentation. Each chapter is organized with a uniform, easy-to-follow format: a brief description of the disorder and pathway; a description of treatment; biomarkers for diagnosis; biomarkers followed for treatment efficacy; biomarkers followed for disease progression; confounding conditions that can either: affect biomarker expression or mimic IEMs; other biomarkers: less established, future. Provides comprehensive information on the tests/biomarkers selection in newborn screening and follow-up of newborn screens Categorizes biomarkers into diagnostic markers, disease follow-up markers, and prognostic biomarkers Covers confounding factors that can alter biomarkers in the absence of inborn errors of metabolism Offers guidance on how to distinguish acquired causes from inborn errors of metabolism

Cancer Biomarkers in Body Fluids

Cancer Biomarkers in Body Fluids Book
Author : Gabriel D. Dakubo
Publisher : Springer Nature
Release : 2019-08-29
ISBN : 3030247252
Language : En, Es, Fr & De

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Book Description :

The ability to measure and monitor cancer biomarkers in “body fluid biopsy” should greatly impact oncologic practice. “Biomarkers in Proximal Fluids”, the third of the “Cancer Biomarkers in Body Fluids” series details cancer signatures in none or minimally circulating body fluids including saliva, sputum, bronchoalveolar lavage fluid, exhaled breath condensate, nipple aspirate fluid, gastric and pancreatic juice, stool, urine, and prostatic, peritoneal and cerebrospinal fluid. These fluids are enriched with biomarkers, especially those emanating from cells of the proximal tissue. Chapter 1 examines the global burden of cancer and the need for regional efforts at primary prevention, early detection and patient care. Chapters 2-12 address tissue-specific biomarkers in associated body fluids. The tumor interstitial fluid as a microenvironment rich in cancer biomarkers is detailed in chapter 13, while chapter 14 looks at the human body fluid microbiome and its evolving role in cancer. Commercially available assays using proximal fluids are examined at the end of the respective chapters. This book complements its predecessors and is equally useful to oncologists, cancer researchers, clinicians, medical students, nurses, diagnostic laboratory and pharmaceutical industry personnel.

Epigenetic Biomarker and Personalized Precision Medicine

Epigenetic Biomarker and Personalized Precision Medicine Book
Author : Jiucun Wang,Dongyi He,Momiao Xiong,Yun Liu
Publisher : Frontiers Media SA
Release : 2020-12-21
ISBN : 2889661849
Language : En, Es, Fr & De

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Book Description :

Download Epigenetic Biomarker and Personalized Precision Medicine book written by Jiucun Wang,Dongyi He,Momiao Xiong,Yun Liu, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Handbook of Ecotoxicology Second Edition

Handbook of Ecotoxicology  Second Edition Book
Author : David J. Hoffman,Barnett A. Rattner,G. Allen Burton, Jr.,John Cairns, Jr.
Publisher : CRC Press
Release : 2002-11-13
ISBN : 142003250X
Language : En, Es, Fr & De

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Book Description :

Handbook of Ecotoxicology, Second Edition focuses on toxic substances and how they affect ecosystems worldwide. It presents methods for quantifying and measuring ecotoxicological effects in the field and in the lab, as well as methods for estimating, predicting, and modeling in ecotoxicology studies. Completely revised and updated with 18 new chapters, this second edition includes contributions from over 75 international experts. Also, a Technical Review Board reviewed all manuscripts for accuracy and currency. This authoritative work is the definitive reference for students, researchers, consultants, and other professionals in the environmental sciences, toxicology, chemistry, biology, and ecology - in academia, industry, and government.

Endocrine Frailty in the Elderly

Endocrine Frailty in the Elderly Book
Author : Sandro La Vignera,Antonio Aversa,Fabio Monzani
Publisher : Frontiers Media SA
Release : 2019-12-04
ISBN : 2889632342
Language : En, Es, Fr & De

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Book Description :

Download Endocrine Frailty in the Elderly book written by Sandro La Vignera,Antonio Aversa,Fabio Monzani, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Environmental Health Perspectives

Environmental Health Perspectives Book
Author : Anonim
Publisher : Unknown
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Environmental Health Perspectives book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.