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Emerging Trends In Computational Biology Bioinformatics And Systems Biology

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Emerging Trends in Computational Biology Bioinformatics and Systems Biology

Emerging Trends in Computational Biology  Bioinformatics  and Systems Biology Book
Author : Hamid R Arabnia,Quoc Nam Tran
Publisher : Morgan Kaufmann
Release : 2015-08-11
ISBN : 0128026464
Language : En, Es, Fr & De

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Book Description :

Emerging Trends in Computational Biology, Bioinformatics, and Systems Biology discusses the latest developments in all aspects of computational biology, bioinformatics, and systems biology and the application of data-analytics and algorithms, mathematical modeling, and simu- lation techniques. • Discusses the development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques to the study of biological and behavioral systems, including applications in cancer research, computational intelligence and drug design, high-performance computing, and biology, as well as cloud and grid computing for the storage and access of big data sets. • Presents a systematic approach for storing, retrieving, organizing, and analyzing biological data using software tools with applications to general principles of DNA/RNA structure, bioinformatics and applications, genomes, protein structure, and modeling and classification, as well as microarray analysis. • Provides a systems biology perspective, including general guidelines and techniques for obtaining, integrating, and analyzing complex data sets from multiple experimental sources using computational tools and software. Topics covered include phenomics, genomics, epigenomics/epigenetics, metabolomics, cell cycle and checkpoint control, and systems biology and vaccination research. • Explains how to effectively harness the power of Big Data tools when data sets are so large and complex that it is difficult to process them using conventional database management systems or traditional data processing applications. Discusses the development and application of data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological and behavioral systems. Presents a systematic approach for storing, retrieving, organizing and analyzing biological data using software tools with applications. Provides a systems biology perspective including general guidelines and techniques for obtaining, integrating and analyzing complex data sets from multiple experimental sources using computational tools and software.

Emerging Trends in Computational Biology Bioinformatics and Systems Biology

Emerging Trends in Computational Biology  Bioinformatics  and Systems Biology Book
Author : Hamid Arabnia,Quoc Tran
Publisher : Unknown
Release : 2015
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Emerging Trends in Computational Biology, Bioinformatics, and Systems Biology discusses the latest developments in all aspects of computational biology, bioinformatics, and systems biology and the application of data-analytics and algorithms, mathematical modeling, and simu- lation techniques." Discusses the development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques to the study of biological and behavioral systems, including applications in cancer research, computational intelligence and drug design, high-performance computing, and biology, as well as cloud and grid computing for the storage and access of big data sets." Presents a systematic approach for storing, retrieving, organizing, and analyzing biological data using software tools with applications to general principles of DNA/RNA structure, bioinformatics and applications, genomes, protein structure, and modeling and classification, as well as microarray analysis." Provides a systems biology perspective, including general guidelines and techniques for obtaining, integrating, and analyzing complex data sets from multiple experimental sources using computational tools and software. Topics covered include phenomics, genomics, epigenomics/epigenetics, metabolomics, cell cycle and checkpoint control, and systems biology and vaccination research." Explains how to effectively harness the power of Big Data tools when data sets are so large and complex that it is difficult to process them using conventional database management systems or traditional data processing applications. Discusses the development and application of data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological and behavioral systems. Presents a systematic approach for storing, retrieving, organizing and analyzing biological data using software tools with applications. Provides a systems biology perspective including general guidelines and techniques for obtaining, integrating and analyzing complex data sets from multiple experimental sources using computational tools and software.

Emerging Trends in Applications and Infrastructures for Computational Biology Bioinformatics and Systems Biology

Emerging Trends in Applications and Infrastructures for Computational Biology  Bioinformatics  and Systems Biology Book
Author : Hamid Arabnia,Quoc Nam Tran
Publisher : Morgan Kaufmann Publishers
Release : 2016-05-06
ISBN : 9780128042038
Language : En, Es, Fr & De

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Book Description :

Emerging Trends in Applications and Infrastructures for Computational Biology, Bioinformatics, and Systems Biology: Systems and Applications covers the latest trends in the field with special emphasis on their applications. The first part covers the major areas of computational biology, development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques for the study of biological and behavioral systems. The second part covers bioinformatics, an interdisciplinary field concerned with methods for storing, retrieving, organizing, and analyzing biological data. The book also explores the software tools used to generate useful biological knowledge. The third part, on systems biology, explores how to obtain, integrate, and analyze complex datasets from multiple experimental sources using interdisciplinary tools and techniques, with the final section focusing on big data and the collection of datasets so large and complex that it becomes difficult to process using conventional database management systems or traditional data processing applications. Explores all the latest advances in this fast-developing field from an applied perspective Provides the only coherent and comprehensive treatment of the subject available Covers the algorithm development, software design, and database applications that have been developed to foster research

Emerging Trends in Applications and Infrastructures for Computational Biology Bioinformatics and Systems Biology

Emerging Trends in Applications and Infrastructures for Computational Biology  Bioinformatics  and Systems Biology Book
Author : Hamid R Arabnia,Quoc Nam Tran
Publisher : Morgan Kaufmann
Release : 2016-03-25
ISBN : 0128042591
Language : En, Es, Fr & De

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Book Description :

Emerging Trends in Applications and Infrastructures for Computational Biology, Bioinformatics, and Systems Biology: Systems and Applications covers the latest trends in the field with special emphasis on their applications. The first part covers the major areas of computational biology, development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques for the study of biological and behavioral systems. The second part covers bioinformatics, an interdisciplinary field concerned with methods for storing, retrieving, organizing, and analyzing biological data. The book also explores the software tools used to generate useful biological knowledge. The third part, on systems biology, explores how to obtain, integrate, and analyze complex datasets from multiple experimental sources using interdisciplinary tools and techniques, with the final section focusing on big data and the collection of datasets so large and complex that it becomes difficult to process using conventional database management systems or traditional data processing applications. Explores all the latest advances in this fast-developing field from an applied perspective Provides the only coherent and comprehensive treatment of the subject available Covers the algorithm development, software design, and database applications that have been developed to foster research

Recent Trends in Computational Omics Concepts and Methodology

Recent Trends in  Computational Omics  Concepts and Methodology  Book
Author : Pramod Katara
Publisher : Unknown
Release : 2020
ISBN : 9781536179415
Language : En, Es, Fr & De

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Book Description :

The last decade has witnessed various technological advances in life sciences, especially high throughput technologies. These technologies provide a way to perform parallel scientific studies in a very short period of time with low cost. High throughput techniques, mainly, next generation sequencing, microarray and mass spectrometry, have strengthened the omics vision in the last decades (study of complete system) and now resulted in well-developed branches of omics i.e., genomics, transcriptomics, proteomics and metabolomics, which deal with almost every level of central dogma of life. Practice of high throughput techniques throughout the world with different aims and objectives resulted in a voluminous data, which required computational applications, i.e., database, algorithm and software to store, process and get biological interpretation from primary raw data. Researchers from different fields are looking to analyze these raw data for different purposes, but lacking of proper information and knowledge in proper documented form creates different kinds of hurdles and raises the challenges. This book contains thirteen chapters that deal with different computational biology/bioinformatics resources and concepts which are already in practice by the scientific community or can be utilized to handle various aspects of different classes of omics data. It includes different computational concepts, algorithm, resources and recent trends belonging to the four major branches of omics (i.e., genomics, transcriptomics, proteomics and metabolomics), including integrative omics. It will help all scholars who are working in any branch of computational omics and bioinformatics field as well as those who would like to perform research at a systemic biology through computational approaches.

Roll with the Times or the Times Roll Over You

Roll with the Times  or the Times Roll Over You Book
Author : Beth R. Bernhardt,Leah H. Hinds,Katina Strauch
Publisher : Purdue University Press
Release : 2017-10-15
ISBN : 1941269117
Language : En, Es, Fr & De

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Book Description :

Over one hundred presentations from the 36th annual Charleston Library Conference (held November 1-5, 2016) are included in this annual proceedings volume. Major themes of the meeting included data visualization, streaming video, analysis and assessment, demand-driven acquisition, and open access publishing. While the Charleston meeting remains a core one for acquisitions librarians in dialog with publishers and vendors, the breadth of coverage of this volume reflects the fact that this conference is now one of the major venues for leaders in the publishing and library communities to shape strategy and prepare for the future. Almost 2,000 delegates attended the 2016 meeting, ranging from the staff of small public library systems to the CEOs of major corporations. This fully indexed, copyedited volume provides a rich source for the latest evidence-based research and lessons from practice in a range of information science fields. Contributors comprise leaders in the library, publishing, and vendor communities.

Computational Immunology

Computational Immunology Book
Author : Josep Bassaganya-Riera
Publisher : Academic Press
Release : 2015-10-21
ISBN : 0128037156
Language : En, Es, Fr & De

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Book Description :

Computational Immunology: Models and Tools encompasses the methodological framework and application of cutting-edge tools and techniques to study immunological processes at a systems level, along with the concept of multi-scale modeling. The book's emphasis is on selected cases studies and application of the most updated technologies in computational modeling, discussing topics such as computational modeling and its usage in immunological research, bioinformatics infrastructure, ODE based modeling, agent based modeling, and high performance computing, data analytics, and multiscale modeling. There are also modeling exercises using recent tools and models which lead the readers to a thorough comprehension and applicability. The book is a valuable resource for immunologists, computational biologists, bioinformaticians, biotechnologists, and computer scientists, as well as all those who wish to broaden their knowledge in systems modeling. Offers case studies with different levels of complexity Provides a detailed view on cutting-edge tools for modeling that are useful to experimentalists with limited computational skills Explores the usage of simulation for hypothesis generation, helping the reader to understand the most valuable points on experimental setting

Molecular Docking for Computer Aided Drug Design

Molecular Docking for Computer Aided Drug Design Book
Author : S. Mohane Coumar
Publisher : Academic Press
Release : 2021-02-17
ISBN : 0128223138
Language : En, Es, Fr & De

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Book Description :

Molecular Docking for Computer-Aided Drug Design: Fundamentals, Techniques, Resources and Applications offers in-depth coverage on the use of molecular docking for drug design. The book is divided into three main sections that cover basic techniques, tools, web servers and applications. It is an essential reference for students and researchers involved in drug design and discovery. Covers the latest information and state-of-the-art trends in structure-based drug design methodologies Includes case studies that complement learning Consolidates fundamental concepts and current practice of molecular docking into one convenient resource

Omics Applications for Systems Biology

Omics Applications for Systems Biology Book
Author : Wan Mohd Aizat,Hoe-Han Goh,Syarul Nataqain Baharum
Publisher : Springer
Release : 2018-10-31
ISBN : 3319987585
Language : En, Es, Fr & De

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Book Description :

This book explains omics at the most basic level, including how this new concept can be properly utilized in molecular and systems biology research. Most reviews and books on this topic have mainly focused on the technicalities and complexity of each omics’ platform, impeding readers to wholly understand its fundamentals and applications. This book tackles such gap and will be most beneficial to novice in this area, university students and even researchers. Basic workflow and practical guidance in each omics are also described, such that scientists can properly design their experimentation effectively. Furthermore, how each omics platform has been conducted in our institute (INBIOSIS) is also detailed, a comprehensive example on this topic to further enhance readers’ understanding. The contributors of each chapter have utilized the platforms in various manner within their own research and beyond. The contributors have also been interactively integrated and combined these different omics approaches in their research, being able to systematically write each chapter with the conscious knowledge of other inter-relating topics of omics. The potential readers and audience of this book can come from undergraduate and postgraduate students who wish to extend their comprehension in the topics of molecular biology and big data analysis using omics platforms. Furthermore, researchers and scientists whom may have expertise in basic molecular biology can extend their experimentation using the omics technologies and workflow outlined in this book, benefiting their research in the long run.

Antibacterial Drug Discovery to Combat MDR

Antibacterial Drug Discovery to Combat MDR Book
Author : Iqbal Ahmad,Shamim Ahmad,Kendra P. Rumbaugh
Publisher : Springer Nature
Release : 2019-11-09
ISBN : 9811398712
Language : En, Es, Fr & De

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Book Description :

This book compiles the latest information in the field of antibacterial discovery, especially with regard to the looming threat of multi-drug resistance. The respective chapters highlight the discovery of new antibacterial and anti-infective compounds derived from microbes, plants, and other natural sources. The potential applications of nanotechnology to the fields of antibacterial discovery and drug delivery are also discussed, and one section of the book is dedicated to the use of computational tools and metagenomics in antibiotic drug discovery. Techniques for efficient drug delivery are also covered. The book provides a comprehensive overview of the progress made in both antibacterial discovery and delivery, making it a valuable resource for academic researchers, as well as those working in the pharmaceutical industry.

Epi Informatics

Epi Informatics Book
Author : Jose Medina-Franco
Publisher : Academic Press
Release : 2016-02-24
ISBN : 0128028092
Language : En, Es, Fr & De

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Book Description :

Epi-Informatics: Discovery and Development of Small Molecule Epigenetic Drugs and Probes features multidisciplinary strategies with strong computational approaches that have led to the successful discovery and/or optimization of compounds that act as modulators of epigenetic targets. This book is intended for all those using or wanting to learn more about computational methodologies in epigenetic drug discovery, including molecular modelers, informaticians, pharmaceutical scientists, and medicinal chemists. With a better understanding of different molecular modeling and cheminformatic approaches, readers can incorporate these techniques into their own drug discovery projects that may involve chemical synthesis and medium- or high-throughput screening. In addition, this book highlights the significance of epigenetic targets to the public health for molecular modelers and chemoinformatians. The goal of this reference is to stimulate ongoing multidisciplinary research and to further improve current computational methodologies and workflows in order to accelerate the discovery and development of epi-drugs and epi-probes. Focuses on the discovery of epi-drugs as candidates to be used in therapy including combined therapies Describes new computational methodologies and screening assays utilizing recent and emerging novel structural data Highlights the discovery, development and optimization of epi-probes, which are molecular probes that elucidate epigenetic mechanisms Includes important topics such as computational-guided optimization of epi-hits, virtual screening to identify novel compounds for epigenetic targets, development and mining of epigenetic molecular databases, SAR modeling of screening data and much more

Membrane Computing

Membrane Computing Book
Author : Grzegorz Rozenberg,Arto Salomaa,José M. Sempere,Claudio Zandron
Publisher : Springer
Release : 2015-12-29
ISBN : 3319284754
Language : En, Es, Fr & De

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Book Description :

This book constitutes revised selected papers from the International Conference on Membrane Computing, CMC 2015, held in Valencia, Spain, in August 2015. The 22 full papers presented in this volume were carefully reviewed and selected from 34 submissions. The volume also contains 3 invited talks in full-paper length.

Mechanisms of Vascular Disease

Mechanisms of Vascular Disease Book
Author : Robert Fitridge
Publisher : Springer Nature
Release : 2020-07-30
ISBN : 3030436837
Language : En, Es, Fr & De

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Book Description :

This extensively revised third edition provides a practically applicable guide to the pathophysiology, assessment and management of vascular disorders encountered in vascular surgical practice. It features detailed information on the latest developments in the pathophysiology of conditions including atherosclerosis, multi-organ failure, limb compartment syndromes and Raynaud’s phenomenon in a clear easy to digest format. Disorders such as reperfusion injuries, vasculitides, and aortic dissection are covered. Furthermore, key topics in vascular and endovascular practice such as radiation biology and radiation safety are also detailed. Each chapter contains a set of learning objectives and key references, enabling the reader to quickly identify key points. Mechanisms of Vascular Disease: A Textbook for Vascular Specialists comprehensively covers a variety of common and unusual pathophysiologies encountered in vascular surgery, and is an ideal resource for both the trainee, and practicing clinical vascular surgeon seeking an up-to-date resource on the topic.

Biomolecular Networks

Biomolecular Networks Book
Author : Luonan Chen,Rui-Sheng Wang,Xiang-Sun Zhang
Publisher : John Wiley & Sons
Release : 2009-06-29
ISBN : 9780470488058
Language : En, Es, Fr & De

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Book Description :

Alternative techniques and tools for analyzing biomolecular networks With the recent rapid advances in molecular biology, high-throughput experimental methods have resulted in enormous amounts of data that can be used to study biomolecular networks in living organisms. With this development has come recognition of the fact that a complicated living organism cannot be fully understood by merely analyzing individual components. Rather, it is the interactions of components or biomolecular networks that are ultimately responsible for an organism's form and function. This book addresses the important need for a new set of computational tools to reveal essential biological mechanisms from a systems biology approach. Readers will get comprehensive coverage of analyzing biomolecular networks in cellular systems based on available experimental data with an emphasis on the aspects of network, system, integration, and engineering. Each topic is treated in depth with specific biological problems and novel computational methods: GENE NETWORKS—Transcriptional regulation; reconstruction of gene regulatory networks; and inference of transcriptional regulatory networks PROTEIN INTERACTION NETWORKS—Prediction of protein-protein interactions; topological structure of biomolecular networks; alignment of biomolecular networks; and network-based prediction of protein function METABOLIC NETWORKS AND SIGNALING NETWORKS—Analysis, reconstruction, and applications of metabolic networks; modeling and inference of signaling networks; and other topics and new trends In addition to theoretical results and methods, many computational software tools are referenced and available from the authors' Web sites. Biomolecular Networks is an indispensable reference for researchers and graduate students in bioinformatics, computational biology, systems biology, computer science, and applied mathematics.

Computational Matter

Computational Matter Book
Author : Susan Stepney,Steen Rasmussen,Martyn Amos
Publisher : Springer
Release : 2018-07-20
ISBN : 3319658263
Language : En, Es, Fr & De

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Book Description :

This book is concerned with computing in materio: that is, unconventional computing performed by directly harnessing the physical properties of materials. It offers an overview of the field, covering four main areas of interest: theory, practice, applications and implications. Each chapter synthesizes current understanding by deliberately bringing together researchers across a collection of related research projects. The book is useful for graduate students, researchers in the field, and the general scientific reader who is interested in inherently interdisciplinary research at the intersections of computer science, biology, chemistry, physics, engineering and mathematics.

Computational Biology and Bioinformatics

Computational Biology and Bioinformatics Book
Author : Ka-Chun Wong
Publisher : CRC Press
Release : 2016-04-27
ISBN : 1498725007
Language : En, Es, Fr & De

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Book Description :

The advances in biotechnology such as the next generation sequencing technologies are occurring at breathtaking speed. Advances and breakthroughs give competitive advantages to those who are prepared. However, the driving force behind the positive competition is not only limited to the technological advancement, but also to the companion data analytical skills and computational methods which are collectively called computational biology and bioinformatics. Without them, the biotechnology-output data by itself is raw and perhaps meaningless. To raise such awareness, we have collected the state-of-the-art research works in computational biology and bioinformatics with a thematic focus on gene regulation in this book. This book is designed to be self-contained and comprehensive, targeting senior undergraduates and junior graduate students in the related disciplines such as bioinformatics, computational biology, biostatistics, genome science, computer science, applied data mining, applied machine learning, life science, biomedical science, and genetics. In addition, we believe that this book will serve as a useful reference for both bioinformaticians and computational biologists in the post-genomic era.

Hybrid Artificial Intelligent Systems

Hybrid Artificial Intelligent Systems Book
Author : Hilde Pérez García,Lidia Sánchez González,Manuel Castejón Limas,Héctor Quintián Pardo,Emilio Corchado Rodríguez
Publisher : Springer Nature
Release : 2019-08-26
ISBN : 3030298590
Language : En, Es, Fr & De

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Book Description :

This volume constitutes the refereed proceedings of the 14th International Conference on Hybrid Artificial Intelligent Systems, HAIS 2019, held in León, Spain, in September 2019. The 64 full papers published in this volume were carefully reviewed and selected from 134 submissions. They are organized in the following topical sections: data mining, knowledge discovery and big data; bio-inspired models and evolutionary computation; learning algorithms; visual analysis and advanced data processing techniques; data mining applications; and hybrid intelligent applications.

Digital Transformation of Identity in the Age of Artificial Intelligence

Digital Transformation of Identity in the Age of Artificial Intelligence Book
Author : Kazuhiko Shibuya
Publisher : Springer Nature
Release : 2020-02-19
ISBN : 9811522480
Language : En, Es, Fr & De

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Book Description :

This book examines the digital transformation of identity in the age of artificial intelligence. It articulates the nature of identity of human beings, based on cutting-edge knowledge in the field of AI and big-data sciences, and discusses identity by drawing on comprehensive investigations in digital social sciences and exploring wider disciplines related to philosophy, ethics, sociology, STS, computer sciences, engineering, and medical sciences. Reviewing contemporary conditions proliferated by advanced technological trends and unveiling social mechanisms of human identity, this book appeals to undergraduate and graduate students as well as academic researchers.

Proceedings of the 2017 Joint Workshop of Fraunhofer IOSB and Institute for Anthropomatics Vision and Fusion Laboratory

Proceedings of the 2017 Joint Workshop of Fraunhofer IOSB and Institute for Anthropomatics  Vision and Fusion Laboratory Book
Author : Beyerer, Juergen,Pak, Alexey,Taphanel, Miro
Publisher : KIT Scientific Publishing
Release : 2018-08-13
ISBN : 373150779X
Language : En, Es, Fr & De

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Book Description :

Download Proceedings of the 2017 Joint Workshop of Fraunhofer IOSB and Institute for Anthropomatics Vision and Fusion Laboratory book written by Beyerer, Juergen,Pak, Alexey,Taphanel, Miro, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Protein Interaction Networks

Protein Interaction Networks Book
Author : Rossen Donev
Publisher : Academic Press
Release : 2022-07-08
ISBN : 0323992323
Language : En, Es, Fr & De

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Book Description :

Protein Interaction Networks, Volume 131 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Advances in Protein Chemistry and Structural Biology series Includes the latest information on protein design and structure