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Ebola Virus Disease

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Ebola Virus Disease

Ebola Virus Disease Book
Author : Adnan Qureshi
Publisher : Academic Press
Release : 2016-01-09
ISBN : 0128042427
Language : En, Es, Fr & De

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Book Description :

Ebola Virus Disease: From Origins to Outbreak covers Ebola virus disease in its entirety from its origins through major outbreaks in the past to the present day outbreak. It contains information on the West Saharan response to Ebola as well as highlights from the field in West Africa from Dr. Qureshi and Dr. Chughtai, helping to solve the primary question of what’s next and aiding in formulating a path forward. With a growing awareness of the devastating effects of this viral disease and an influx of topical research, this book provides the information the global community of researchers, clinicians and students need to better inform their research and study of Ebola virus disease. Includes perspectives from the 2014-2015 outbreak from the field Provides a detailed overview of the origins of Ebola virus through present day discoveries Written with an integrative approach, incorporating scientific research with insights from the field

Ebola

Ebola Book
Author : Dorothy H. Crawford
Publisher : Oxford University Press
Release : 2016
ISBN : 0198759991
Language : En, Es, Fr & De

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Book Description :

First discovered in 1976, and long regarded as an easily manageable virus affecting isolated rural communities, Ebola rocketed to world prominence in 2014 as a deadly epidemic swept through Guinea, Sierra Leone, and Liberia in West Africa. Thousands of people died as the extraordinarily contagious disease spread rapidly from villages to urban centres. Initial quarantine responses proved often too little and too late, and the medical infrastructure of the affected countries struggled to cope. By August 2014, several months after the start of the outbreak, the WHO declared the epidemic a public health emergency and international aid teams and volunteers began to pour in. But halting the epidemic proved to be hugely challenging, not only in terms of the practicalities of dealing with the sheer numbers of patients carrying the highly infectious virus, but in dealing with social and cultural barriers. The author, Dorothy Crawford, visited Sierra Leone while the epidemic was ongoing and met with those on the frontline in the fight against the virus. In Ebola Crawford combines personal accounts from these brave medical workers with the latest scientific reports to tell the story of the epidemic as it unfolded, and how it has changed our understanding of the virus. She looks at its origin and spread, the international response, and its devastating legacy to the health of those living in the three worst affected countries. She describes the efforts to prevent international spread, the treatment options for Ebola, including the drug and vaccine trials that eventually got underway in 2015, and the sensitive issue of running trials of experimental therapies during a lethal epidemic. Our understanding of the Ebola virus continues to develop as long-term health problems and complications following recovery from the disease are being identified. Epidemics of Ebola or other dangerous microbes will continue to threaten the world regularly. Already concerns have been raised by the possible impact of the Zika virus. What lessons have been learnt from Ebola? How, asks Crawford, might we prevent a repeat of the awful suffering seen in 2014-16?

The Ebola Epidemic in West Africa

The Ebola Epidemic in West Africa Book
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Release : 2016-12-30
ISBN : 0309450063
Language : En, Es, Fr & De

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Book Description :

The most recent Ebola epidemic that began in late 2013 alerted the entire world to the gaps in infectious disease emergency preparedness and response. The regional outbreak that progressed to a significant public health emergency of international concern (PHEIC) in a matter of months killed 11,310 and infected more than 28,616. While this outbreak bears some unique distinctions to past outbreaks, many characteristics remain the same and contributed to tragic loss of human life and unnecessary expenditure of capital: insufficient knowledge of the disease, its reservoirs, and its transmission; delayed prevention efforts and treatment; poor control of the disease in hospital settings; and inadequate community and international responses. Recognizing the opportunity to learn from the countless lessons of this epidemic, the National Academies of Sciences, Engineering, and Medicine convened a workshop in March 2015 to discuss the challenges to successful outbreak responses at the scientific, clinical, and global health levels. Workshop participants explored the epidemic from multiple perspectives, identified important questions about Ebola that remained unanswered, and sought to apply this understanding to the broad challenges posed by Ebola and other emerging pathogens, to prevent the international community from being taken by surprise once again in the face of these threats. This publication summarizes the presentations and discussions from the workshop.

Ebola Virus Disease

Ebola Virus Disease Book
Author : Marta Lado
Publisher : Springer
Release : 2019-04-10
ISBN : 3319948547
Language : En, Es, Fr & De

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Book Description :

This current manual gives an overview to management of Ebola Virus Disease outbreaks from a practical point of view. It gives an introduction to the topic, reviews the history and previous outbreaks of Ebola virus disease and gives insight to clinical features of the disease. The major part of the book presents ways of response including screening, isolation and personal protection equipment as well as waste management during disease outbreaks. New therapies and experimental drugs are discussed in further detail. The last part of the volume deals with all aspects of diagnostics and practical laboratory handling of Ebola virus. Dr. Marta Lado is the clinical lead of the King’s Sierra Leone Partnership in country team. She brings together a group of authors aggregating both well-grounded basic knowledge on Ebola virus as well as deep experience with Ebola Virus Disease in the field.

Current Topics in Tropical Emerging Diseases and Travel Medicine

Current Topics in Tropical Emerging Diseases and Travel Medicine Book
Author : Alfonso J. Rodriguez-Morales
Publisher : BoD – Books on Demand
Release : 2018-12-19
ISBN : 1789848245
Language : En, Es, Fr & De

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Book Description :

Tropical emerging diseases pose a significant risk for the circulation of old and new pathogens in areas previously unknown, also implying the possibility of new morbidities and mortalities and new consequences for naïve populations. Globalization, migration and travel are key factors for tropical diseases, and represent the need for integration of tropical medicine, travel medicine and epidemiology in the understanding of such complex situations. Neglected tropical diseases such as leprosy or Chagas disease, arboviral diseases, HIV, Ebola, and arenaviral infections are just a few examples. This book tries to update significant epidemiological and clinical research in many aspects with a multinational perspective.

Ebola and Marburg Viruses

Ebola and Marburg Viruses Book
Author : Hans-Dieter Klenk,Heinz Feldmann
Publisher : Garland Science
Release : 2004
ISBN : 9780954523237
Language : En, Es, Fr & De

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Book Description :

The Ebola and Marburg viruses are a pair of filoviruses that are among the most lethal hemorrhagic viruses on the planet. The authors present a review of past and current research into these pathogens, including 12 papers addressing the structure of the viral proteins; genomic replication; molecular mechanisms of entry; pathogenesis in nonhuman primates, guinea pigs, and mice; virus modulation of innate immunity; and cellular and molecular mechanisms of Ebola pathogenicity and related approaches to vaccine development.

Oxford Textbook of Zoonoses

Oxford Textbook of Zoonoses Book
Author : S.R. Palmer,Lord Soulsby,Paul Torgerson,David W. G. Brown
Publisher : OUP Oxford
Release : 2011-07-14
ISBN : 9780198570028
Language : En, Es, Fr & De

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Book Description :

Divided into three sections along the lines of bacteriology, parasitology and virology, this book comprehensively provides a systematic, cross disciplinary approach to the science and control of all zoonoses, written by international specialists in human and veterinary medicine.

Advances in Ebola Control

Advances in Ebola Control Book
Author : Samuel Ikwaras Okware
Publisher : BoD – Books on Demand
Release : 2018-04-26
ISBN : 1789230705
Language : En, Es, Fr & De

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Book Description :

Ebola epidemics have had immediate and lasting impact in Africa and beyond, with its high case fatality and societal disruption. Its rapid spread, coupled with the limited knowledge, serves as a recipe for disaster and panic in the community. Health workers are particularly at risk, paying heavily with their lives. Sharing knowledge from various experts in basic sciences that support vaccine and drug development, as well as improving community surveillance and case management, enriches our understanding of this highly fatal and contagious disease. In a world that is fast becoming a global village, communicable diseases from low-resource setting are gradually becoming a global health threat. This book seeks to discuss emerging advances in the Ebola control.

Clinical Management of Patients with Viral Haemorrhagic Fever

Clinical Management of Patients with Viral Haemorrhagic Fever Book
Author : World Health Organization
Publisher : World Health Organization
Release : 2016-05-03
ISBN : 9241549602
Language : En, Es, Fr & De

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Book Description :

First published in March 2014 under the title "Clinical management of patients with viral haemorrhagic fever: a pocket guide for front-line health workers: interim emergency guidance for West Africa".

Ebola

Ebola Book
Author : George Ealy,Carolyn A. Dehlinger
Publisher : Jones & Bartlett Publishers
Release : 2015-08-03
ISBN : 1284107183
Language : En, Es, Fr & De

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Book Description :

Authored by two professionals in the medical and science fields, Ebola: An Emerging Infectious Disease Case Study analyzes the recent outbreak of the virus from a variety of angles and provides context for our understanding of emerging infectious diseases, how they are treated, and how agencies and governments respond to them.

Ebola Virus Disease

Ebola Virus Disease Book
Author : Applied Research Press,James Bonnar
Publisher : CreateSpace
Release : 2014-11-12
ISBN : 9781503209985
Language : En, Es, Fr & De

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Book Description :

Connecting minds with knowledge. With its acclaimed authors, cutting-edge content, emphasis on medical relevance, and coverage based on landmark research, Ebola Virus Disease: A Guide for Corporations and Large Institutions has earned an impeccable reputation as an authoritative and exciting curated research journal and learning aid, perfect for students, medical professionals and other sophisticated readers. Hundreds of hours were spent compiling and editing this volume such that its readers are conveniently brought up-to-speed on the subject, presenting many of the latest and most important developments in the field. This volume presents 20 cutting-edge research papers on ebola, curated by our experts for maximal significance. Articles include: Transmission dynamics and control of Ebola virus disease (EVD): a review; Ebola, epidemics, and ethics - what we have learned; Outbreaks of Ebola virus disease in Africa: the beginnings of a tragic saga; Need of surveillance response systems to combat Ebola outbreaks and other emerging infectious diseases in African countries; Recombinant lentogenic Newcastle disease virus expressing Ebola virus GP infects cells independently of exogenous trypsin and uses macropinocytosis as the major pathway for cell entry; Impact on nurses of ebola outbreak; Guidance for contact tracing of cases of Lassa fever, Ebola or Marburg haemorrhagic fever on an airplane: results of a European expert consultation; “A time of fear”: local, national, and international responses to a large Ebola outbreak in Uganda; Prediction and identification of mouse cytotoxic T lymphocyte epitopes in Ebola virus glycoproteins; Induction of ebolavirus cross-species immunity using retrovirus-like particles bearing the Ebola virus glycoprotein lacking the mucin-like domain; Ebola haemorrhagic fever outbreak in Masindi District, Uganda: outbreak description and lessons learned; Tackling Ebola: new insights into prophylactic and therapeutic intervention strategies; Full-length Ebola glycoprotein accumulates in the endoplasmic reticulum; A bioengineering approach for rational vaccine design towards the Ebola Virus; Large serological survey showing cocirculation of Ebola and Marburg viruses in Gabonese bat populations, and a high seroprevalence of both viruses in Rousettus aegyptiacus; Effect of Ebola virus proteins GP, NP and VP35 on VP40 VLP morphology; Packaging of actin into Ebola virus VLPs; and Ebola virus infection inversely correlates with the overall expression levels of promyelocytic leukaemia (PML) protein in cultured cells.

The Hot Zone

The Hot Zone Book
Author : Richard Preston
Publisher : Corgi
Release : 1995
ISBN : 9780552143035
Language : En, Es, Fr & De

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Book Description :

Imagine a killer with the infectiousness of the common cold and power of the Black Death. Imagine something so deadly that it wipes out 90% of those it touches. Imagine an organism against which there is no defence. But you don't need to imagine. Such a killer exists: it is a virus and its name is Ebola. The Hot Zone tells what happens when the unthinkable becomes reality: when a deadly virus, from the rain forests of Africa, crosses continents and infects a monkey house ten miles from the White House. Ebola is that reality. It has the power to decimate the world's population. Try not to panic. It will be back. There is nothing you can do...

Ebola Virus Disease

Ebola Virus Disease Book
Author : Applied Research Press,James Bonnar
Publisher : CreateSpace
Release : 2014-11-12
ISBN : 9781503210400
Language : En, Es, Fr & De

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Book Description :

Connecting minds with knowledge. With its acclaimed authors, cutting-edge content, emphasis on medical relevance, and coverage based on landmark research, Ebola Virus Disease: A Guide for Federal, State and Local Governments has earned an impeccable reputation as an authoritative and exciting curated research journal and learning aid, perfect for students, medical professionals and other sophisticated readers. Hundreds of hours were spent compiling and editing this volume such that its readers are conveniently brought up-to-speed on the subject, presenting many of the latest and most important developments in the field. This volume presents 20 cutting-edge research papers on ebola, curated by our experts for maximal significance. Articles include: Transmission dynamics and control of Ebola virus disease (EVD): a review; Ebola, epidemics, and ethics - what we have learned; Outbreaks of Ebola virus disease in Africa: the beginnings of a tragic saga; Need of surveillance response systems to combat Ebola outbreaks and other emerging infectious diseases in African countries; Recombinant lentogenic Newcastle disease virus expressing Ebola virus GP infects cells independently of exogenous trypsin and uses macropinocytosis as the major pathway for cell entry; Impact on nurses of ebola outbreak; Guidance for contact tracing of cases of Lassa fever, Ebola or Marburg haemorrhagic fever on an airplane: results of a European expert consultation; “A time of fear”: local, national, and international responses to a large Ebola outbreak in Uganda; Prediction and identification of mouse cytotoxic T lymphocyte epitopes in Ebola virus glycoproteins; Induction of ebolavirus cross-species immunity using retrovirus-like particles bearing the Ebola virus glycoprotein lacking the mucin-like domain; Ebola haemorrhagic fever outbreak in Masindi District, Uganda: outbreak description and lessons learned; Tackling Ebola: new insights into prophylactic and therapeutic intervention strategies; Full-length Ebola glycoprotein accumulates in the endoplasmic reticulum; A bioengineering approach for rational vaccine design towards the Ebola Virus; Large serological survey showing cocirculation of Ebola and Marburg viruses in Gabonese bat populations, and a high seroprevalence of both viruses in Rousettus aegyptiacus; Effect of Ebola virus proteins GP, NP and VP35 on VP40 VLP morphology; Packaging of actin into Ebola virus VLPs; and Ebola virus infection inversely correlates with the overall expression levels of promyelocytic leukaemia (PML) protein in cultured cells.

The Hot Zone

The Hot Zone Book
Author : Richard Preston
Publisher : Anchor
Release : 2012-03-14
ISBN : 0307817652
Language : En, Es, Fr & De

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Book Description :

The bestselling landmark account of the first emergence of the Ebola virus. Now a mini-series drama starring Julianna Margulies, Topher Grace, Liam Cunningham, James D'Arcy, and Noah Emmerich on National Geographic. A highly infectious, deadly virus from the central African rain forest suddenly appears in the suburbs of Washington, D.C. There is no cure. In a few days 90 percent of its victims are dead. A secret military SWAT team of soldiers and scientists is mobilized to stop the outbreak of this exotic "hot" virus. The Hot Zone tells this dramatic story, giving a hair-raising account of the appearance of rare and lethal viruses and their "crashes" into the human race. Shocking, frightening, and impossible to ignore, The Hot Zone proves that truth really is scarier than fiction.

Fevers Feuds and Diamonds

Fevers  Feuds  and Diamonds Book
Author : Paul Farmer
Publisher : Farrar, Straus and Giroux
Release : 2020-11-17
ISBN : 0374716986
Language : En, Es, Fr & De

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Book Description :

“Paul Farmer brings his considerable intellect, empathy, and expertise to bear in this powerful and deeply researched account of the Ebola outbreak that struck West Africa in 2014. It is hard to imagine a more timely or important book.” —Bill and Melinda Gates "[The] history is as powerfully conveyed as it is tragic . . . Illuminating . . . Invaluable." —Steven Johnson, The New York Times Book Review In 2014, Sierra Leone, Liberia, and Guinea suffered the worst epidemic of Ebola in history. The brutal virus spread rapidly through a clinical desert where basic health-care facilities were few and far between. Causing severe loss of life and economic disruption, the Ebola crisis was a major tragedy of modern medicine. But why did it happen, and what can we learn from it? Paul Farmer, the internationally renowned doctor and anthropologist, experienced the Ebola outbreak firsthand—Partners in Health, the organization he founded, was among the international responders. In Fevers, Feuds, and Diamonds, he offers the first substantive account of this frightening, fast-moving episode and its implications. In vibrant prose, Farmer tells the harrowing stories of Ebola victims while showing why the medical response was slow and insufficient. Rebutting misleading claims about the origins of Ebola and why it spread so rapidly, he traces West Africa’s chronic health failures back to centuries of exploitation and injustice. Under formal colonial rule, disease containment was a priority but care was not – and the region’s health care woes worsened, with devastating consequences that Farmer traces up to the present. This thorough and hopeful narrative is a definitive work of reportage, history, and advocacy, and a crucial intervention in public-health discussions around the world.

Disease Control Priorities Third Edition Volume 9

Disease Control Priorities  Third Edition  Volume 9  Book
Author : Dean T. Jamison,Hellen Gelband,Susan Horton,Prabhat Jha,Charles N. Mock,Rachel Nugent
Publisher : World Bank Publications
Release : 2017-12-06
ISBN : 1464805288
Language : En, Es, Fr & De

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Book Description :

As the culminating volume in the DCP3 series, volume 9 will provide an overview of DCP3 findings and methods, a summary of messages and substantive lessons to be taken from DCP3, and a further discussion of cross-cutting and synthesizing topics across the first eight volumes. The introductory chapters (1-3) in this volume take as their starting point the elements of the Essential Packages presented in the overview chapters of each volume. First, the chapter on intersectoral policy priorities for health includes fiscal and intersectoral policies and assembles a subset of the population policies and applies strict criteria for a low-income setting in order to propose a "highest-priority" essential package. Second, the chapter on packages of care and delivery platforms for universal health coverage (UHC) includes health sector interventions, primarily clinical and public health services, and uses the same approach to propose a highest priority package of interventions and policies that meet similar criteria, provides cost estimates, and describes a pathway to UHC.

Therapeutics for Ebola virus disease 19 August 2022

Therapeutics for Ebola virus disease  19 August 2022 Book
Author : Anonim
Publisher : World Health Organization
Release : 2022-08-19
ISBN : 9240055746
Language : En, Es, Fr & De

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Book Description :

Ebola virus disease (EVD) is a life-threatening disease caused by Ebola virus (EBOV; Zaire ebolavirus). Viruses of the genus Ebolavirus (of the family Filoviridae) can cause life-threatening disease. EBOV causes outbreaks of EVD, historically the most severe and most frequent. This guidance, due to the evidence available, is directed only to the treatment of EVD, the disease caused by EBOV (Zaire ebolavirus). During early EVD, patients present with a non-specific febrile illness, followed by gastrointestinal signs and symptoms that frequently lead to hypovolaemia, metabolic acidosis, hypoglycaemia, and multi-organ failure. EVD case fatality remains high, with a pooled case fatality rate of 60% (95% confidence interval [CI]: 47–73%) in outbreaks from 2010–2020. Following the publication of an RCT demonstrating superior efficacy of two EVD therapeutics, in comparison to the ZMapp control arm, WHO proposed to develop a new guideline. This is a new guideline written to accompany the optimized supportive care (oSoC) for EVD standard operating procedures. The guideline aims to summarize high quality evidence for EVD therapeutics and make recommendations for their use.

Ebola

Ebola Book
Author : Joseph R. Masci,Elizabeth Bass
Publisher : CRC Press
Release : 2017-08-07
ISBN : 1351646168
Language : En, Es, Fr & De

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Book Description :

Ebola: Clinical Patterns, Public Health Concerns is a concise description and discussion of the Ebola virus and disease. The intended audience is medical practitioners, including those working in endemic areas as well as health-facility planners and public health practitioners. The book fills an important gap between large texts covering not only Ebola but other hemorrhagic fever viruses and brief pamphlet-style publications on the public health aspects of the infection. In light of the recent large outbreak in West Africa, this book is a part of the developing foundation needed to deal with emerging diseases.

Rapid Ethnographies

Rapid Ethnographies Book
Author : Cecilia Vindrola-Padros
Publisher : Cambridge University Press
Release : 2021-01-21
ISBN : 110849336X
Language : En, Es, Fr & De

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Book Description :

Based on real case studies, this is the first practical guide to rapid ethnographies, exploring their history, design and implementation.

Revolutionizing Tropical Medicine

Revolutionizing Tropical Medicine Book
Author : Kerry Atkinson,Prof. David Mabey
Publisher : John Wiley & Sons
Release : 2019-05-23
ISBN : 1119282659
Language : En, Es, Fr & De

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Book Description :

A comprehensive resource describing innovative technologies and digital health tools that can revolutionize the delivery of health care in low- to middle-income countries, particularly in remote rural impoverished communities Revolutionizing Tropical Medicine offers an up-to-date guide for healthcare and other professionals working in low-resource countries where access to health care facilities for diagnosis and treatment is challenging. Rather than suggesting the expensive solution of building new bricks and mortar clinics and hospitals and increasing the number of doctors and nurses in these deprived areas, the authors propose a complete change of mindset. They outline a number of ideas for improving healthcare including rapid diagnostic testing for infectious and non-infectious diseases at a point-of-care facility, together with low cost portable imaging devices. In addition, the authors recommend a change in the way in which health care is delivered. This approach requires task-shifting within the healthcare provision system so that nurses, laboratory technicians, pharmacists and others are trained in the newly available technologies, thus enabling faster and more appropriate triage for people requiring medical treatment. This text: Describes the current burden of communicable and non-communicable diseases in low- to middle-income countries throughout the world Describes the major advances in healthcare outcomes in low-to middle-income countries derived from implementation of the United Nations/World Health Organisation’s 2000 Millennium Development Goals Provides a review of inexpensive rapid diagnostic point-of-care tests for infectious diseases in low-resource countries, particularly for people living in remote rural areas Provides a review of other rapid point-of-care services for assessing hematological function, biochemical function, renal function, hepatic function and status including hepatitis, acid-base balance, sickle cell disease, severe acute malnutrition and spirometry Explores the use of low-cost portable imaging devices for use in remote rural areas including a novel method of examining the optic fundus using a smartphone and the extensive value of portable ultrasound scanning when x-ray facilities are not available Describes the use of telemedicine in the clinical management of both children and adults in remote rural settings Looks to the future of clinical management in remote impoverished rural settings using nucleic acid identification of pathogens, the use of nanoparticles for water purification, the use of drones, the use of pulse oximetry and the use of near-infrared spectroscopy Finally, it assesses the potential for future healthcare improvement in impoverished areas and how the United Nations/World Health Organization 2015 Sustainable Development Goals are approaching this. Written for physicians, infectious disease specialists, pathologists, radiologists, nurses, pharmacists and other health care workers, as well as government healthcare managers, Revolutionizing Tropical Medicine is a new up-to-date essential and realistic guide to treating and diagnosing patients in low-resource tropical countries based on new technologies.