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Durability And Reliability Of Medical Polymers

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Durability and Reliability of Medical Polymers

Durability and Reliability of Medical Polymers Book
Author : Mike Jenkins,Artemis Stamboulis
Publisher : Elsevier
Release : 2012-08-13
ISBN : 0857096516
Language : En, Es, Fr & De

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Book Description :

Given the widespread use of polymers in medical devices, the durability and reliability of this material in use is an area of critical importance. Durability and reliability of medical polymers reviews the performance of both bioresorbable and non-bioresorbable medical polymers. Part one provides a review of the types and properties of bioresorbable medical polymers. The effect of molecular structure on properties is discussed, along with the processing of bioresorbable and other polymers for medical applications. Transport phenomena and the degradation of bioresorbable medical polymers are reviewed, before an exploration of synthetic bioresorbable polymers and their use in orthopaedic tissue regeneration. Part two goes on to explore the durability and reliability of non-bioresorbable medical polymers, and wear processes in polymer implants and ageing processes of biomedical polymers in the body are discussed in depth, before an investigation into manufacturing defects and the failure of synthetic polymeric medical devices. With its distinguished editors and international team of expert contributors, Durability and reliability of medical polymers is an essential tool for all materials scientists, researchers and engineers involved in the design, development and application of medical polymers, whilst also providing a helpful overview of the subject for biologists, chemist and clinicians. Comprehensively examines the performance of both bioresorbable and non-bioresorbable medical polymers Discusses the processing of bioresorbable and other polymers for medical applications, before reviewing the degradation of bioresorbable medical polymers Explores the durability and reliability of non-bioresorbable medical polymers and discusses wear processes in polymer implants and ageing processes of biomedical polymers in the body

Durability and Reliability of Medical Polymers

Durability and Reliability of Medical Polymers Book
Author : Mike Jenkins,Artemis Stamboulis
Publisher : Woodhead Pub Limited
Release : 2012
ISBN : 9781845699291
Language : En, Es, Fr & De

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Book Description :

Given the widespread use of polymers in medical devices, the durability and reliability of this material in use is an area of critical importance. The performance of both bioresorbable and non-bioresorbable medical polymers are reviewed.

Plastics in Medical Devices

Plastics in Medical Devices Book
Author : Vinny R. Sastri
Publisher : William Andrew
Release : 2021-10-01
ISBN : 0323851274
Language : En, Es, Fr & De

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Book Description :

Plastics in Medical Devices: Properties, Requirements, and Applications, Third Edition provides a comprehensive overview on the main types of plastics used in medical device applications. The book focuses on the applications and properties that are most important in medical device design, such as chemical resistance, sterilization capability and biocompatibility. The roles of additives, stabilizers and fillers as well as the synthesis and production of polymers are covered and backed up with a wealth of data tables. The book also covers other key aspects in detail, including regulations, compliance, purchasing controls and supplier controls, and process validation. This updated edition has been thoroughly revised with regard to new plastic materials, applications and requirements. This is a valuable resource for engineers, scientists and managers involved in the design and manufacture of medical devices. Presents detailed coverage of commercially available plastics used in medical device applications, organized by polymer type and supported by data Includes up-to-date regulatory requirements and practical information on purchasing and supplier controls, process validation and risk management Supports the development, marketing and commercialization of medical devices and materials for use in medical devices

Science and Principles of Biodegradable and Bioresorbable Medical Polymers

Science and Principles of Biodegradable and Bioresorbable Medical Polymers Book
Author : Xiang Cheng Zhang
Publisher : Woodhead Publishing
Release : 2016-09-22
ISBN : 0081003935
Language : En, Es, Fr & De

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Book Description :

Science and Principles of Biodegradable and Bioresorbable Medical Polymers: Materials and Properties provides a practical guide to the use of biodegradable and bioresorbable polymers for study, research, and applications within medicine. Fundamentals of the basic principles and science behind the use of biodegradable polymers in advanced research and in medical and pharmaceutical applications are presented, as are important new concepts and principles covering materials, properties, and computer modeling, providing the reader with useful tools that will aid their own research, product design, and development. Supported by practical application examples, the scope and contents of the book provide researchers with an important reference and knowledge-based educational and training aid on the basics and fundamentals of these important medical polymers. Provides a practical guide to the fundamentals, synthesis, and processing of bioresorbable polymers in medicine Contains comprehensive coverage of material properties, including unique insights into modeling degradation Written by an eclectic mix of international authors with experience in academia and industry

Biomaterials in Plastic Surgery

Biomaterials in Plastic Surgery Book
Author : W Peters,H Brandon,K L Jerina,C Wolf,V L Young
Publisher : Elsevier
Release : 2012-07-02
ISBN : 0857096419
Language : En, Es, Fr & De

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Book Description :

Employed for both cosmetic and reconstructive purposes, breast implants are one of the most widely-used and controversial prostheses available. The development of safe, reliable products is vital to the future of this important field of surgery. Biomaterials in plastic surgery reviews the history, materials and safety issues associated with breast implants. Beginning with an introduction to the history of biomaterials used for breast augmentation, Biomaterials in plastic surgery goes on to discuss development issues. It then discusses the chemistry and physical properties of biomedical silicones before reviewing cohesive gel and polyurethane foam implants. The book concludes by analysing the epidemiological evidence on the safety issues relating to breast implants, followed by a review of retrieval and analysis of breast implants emphasizing strength, durability and failure mechanisms. With its distinguished editors and international team of expert contributors, Biomaterials in plastic surgery is an important guide for surgeons, manufacturers and all those researching this important field. Comprehensively examines the history, materials and safety issues associated with breast implants Provides an overview of the history of biomaterials used for breast augmentation and goes on to discuss the development and chemical and physical properties of biomedical silicones Reviews cohesive gel breast implants and polyurethane foam breast implants

Biosynthetic Polymers for Medical Applications

Biosynthetic Polymers for Medical Applications Book
Author : Laura Poole-Warren,Penny Martens,Rylie Green
Publisher : Elsevier
Release : 2015-11-23
ISBN : 1782421130
Language : En, Es, Fr & De

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Book Description :

Biosynthetic Polymers for Medical Applications provides the latest information on biopolymers, the polymers that have been produced from living organisms and are biodegradable in nature. These advanced materials are becoming increasingly important for medical applications due to their favorable properties, such as degradability and biocompatibility. This important book provides readers with a thorough review of the fundamentals of biosynthetic polymers and their applications. Part One covers the fundamentals of biosynthetic polymers for medical applications, while Part Two explores biosynthetic polymer coatings and surface modification. Subsequent sections discuss biosynthetic polymers for tissue engineering applications and how to conduct polymers for medical applications. Comprehensively covers all major medical applications of biosynthetic polymers Provides an overview of non-degradable and biodegradable biosynthetic polymers and their medical uses Presents a specific focus on coatings and surface modifications, biosynthetic hydrogels, particulate systems for gene and drug delivery, and conjugated conducting polymers

Modelling Degradation of Bioresorbable Polymeric Medical Devices

Modelling Degradation of Bioresorbable Polymeric Medical Devices Book
Author : J Pan
Publisher : Elsevier
Release : 2014-10-24
ISBN : 1782420258
Language : En, Es, Fr & De

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Book Description :

The use of bioresorbable polymers in stents, fixation devices and tissue engineering is revolutionising medicine. Both industry and academic researchers are interested in using computer modelling to replace some experiments which are costly and time consuming. This book provides readers with a comprehensive review of modelling polymers and polymeric medical devices as an alternative to practical experiments. Chapters in part one provide readers with an overview of the fundamentals of biodegradation. Part two looks at a wide range of degradation theories for bioresorbable polymers and devices. The final set of chapters look at advances in modelling biodegradation of bioresorbable polymers. This book is an essential guide to those concerned with replacing tests and experiments with modelling. Provides a comprehensive mathematical framework for computer modelling of polymers and polymeric medical devices that can significantly reduce the number of experiments needed. Reviews the fundamental methods of modelling degradation, and applies these to particular materials including amorphous bioresorbable polyesters, semicrystalline biodegradable polyesters, and composite materials made of biodegradable polyesters and triclcium phosphates

Bioresorbable Polymers for Biomedical Applications

Bioresorbable Polymers for Biomedical Applications Book
Author : Giuseppe Perale,Jöns Hilborn
Publisher : Woodhead Publishing
Release : 2016-08-24
ISBN : 0081002661
Language : En, Es, Fr & De

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Book Description :

Bioresorbable Polymers for Biomedical Applications: From Fundamentals to Translational Medicine provides readers with an overview of bioresorbable polymeric materials in the biomedical field. A useful resource for materials scientists in industry and academia, offering information on the fundamentals and considerations, synthesis and processing, and the clinical and R and D applications of bioresorbable polymers for biomedical applications. Focuses on biomedical applications of bioresorbable polymers Features a comprehensive range of topics including fundamentals, synthesis, processing, and applications Provides balanced coverage of the field with contributions from academia and industry Includes clinical and R and D applications of bioresorbable polymers for biomedical applications

Materials for Biomedical Engineering Absorbable Polymers

Materials for Biomedical Engineering  Absorbable Polymers Book
Author : Alexandru Grumezescu,Valentina Grumezescu
Publisher : Elsevier
Release : 2019-06-28
ISBN : 0128184167
Language : En, Es, Fr & De

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Book Description :

Materials for Biomedical Engineering: Absorbable Polymers provides a detailed and comprehensive review of recent progress in absorbable biopolymers and their impact on biomedical engineering. The book's main focus lies in their classification, processing, properties and performance, biocompatibility, and their applications in tissue engineering, drug delivery, bone repair and regenerative medicine. The most up-to-date methods used to obtain such polymers and how to improve their properties is discussed in detail. This book provides readers with a comprehensive and updated review of the latest research in the field of absorbable polymers for biomedical applications. Provides knowledge of the range of absorbable polymers currently available, enabling the reader to make optimal materials selection decisions Presents detailed information on current and proposed applications of the latest developments Includes a strong emphasis on chemistry and physico-chemical characterization of these materials and their application in biomedical engineering

Bioresorbable Polymers

Bioresorbable Polymers Book
Author : Declan Devine
Publisher : Walter de Gruyter GmbH & Co KG
Release : 2019-04-15
ISBN : 3110640570
Language : En, Es, Fr & De

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Book Description :

Bioresorbable implants can be processed via conventional polymer processing methods such as extrusion, injection and compressing moulding, solvent spinning or casting. This book addresses issues and highlights recent advances in the use of biodegradable polymers. It is intended for researchers utilizing biodegradable polymers in areas from tissue engineering to controlled release of active pharmaceuticals, as well as industrial processors.

Functional Materials and Advanced Manufacturing

Functional Materials and Advanced Manufacturing Book
Author : Chander Prakash,Sunpreet Singh,J. Paulo Davim
Publisher : CRC Press
Release : 2020-10-26
ISBN : 1000193209
Language : En, Es, Fr & De

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Book Description :

This three-volume set addresses a new knowledge of function materials, their processing, and their characterizations. "Functional and Smart Materials", covered the synthesis and fabrication route of functional and smart materials for universal applications such as material science, mechanical engineering, manufacturing, metrology, nanotechnology, physics, chemical, biology, chemistry, civil engineering, and food science. "Advanced Manufacturing and Processing Technology" covers the advanced manufacturing technologies includes coating, deposition, cladding, nanotechnology, surface finishing, precision machining, processing, and emerging advanced manufacturing technologies for processing of materials for functional applications. "Characterization, Testing, Measurement and Metrology" covered the application of new and advanced characterization techniques to investigate and analysis the processed materials.

Functional and Smart Materials

Functional and Smart Materials Book
Author : Chander Prakash,Sunpreet Singh,J. Paulo Davim
Publisher : CRC Press
Release : 2020-10-25
ISBN : 1000193152
Language : En, Es, Fr & De

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Book Description :

This book presents a comprehensive and broad-spectrum picture of the state-of-the-art research, development, and commercial prospective of various discoveries conducted in the real world of functional and smart materials. This book presents various synthesis and fabrication routes of function and smart materials for universal applications such as material science, mechanical engineering, manufacturing, metrology, nanotechnology, physics, biology, chemistry, civil engineering, and food science. The content of this book opens various scientific horizons proved to be beneficial for uplifting the standards of day-to-day practices in the biomedical domain. Myriad innovations in the materials science and engineering are transforming our everyday lives in extraordinary ways. This book captures the emerging areas of materials science and advanced manufacturing engineering and presents recent trends in research for researchers, field engineers, and academic professionals.

Forensic Polymer Engineering

Forensic Polymer Engineering Book
Author : Peter Rhys Lewis
Publisher : Woodhead Publishing
Release : 2016-06-09
ISBN : 0081007280
Language : En, Es, Fr & De

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Book Description :

Forensic Polymer Engineering: Why Polymer Products Fail in Service, Second Edition presents and explains the latest forensic engineering techniques used in the investigation of failed polymer materials that are illustrated with a very large number of detailed case studies which show the different types of failure and the forensic engineering techniques used in their investigation. In this updated edition, new case studies have been added to include patent disputes and failed products such as spiral wound wall storage tanks, lithium battery explosions, water bottle failures, and breast implant failures (such as the PIP scandal). New images demonstrating failure have been included, and images from the previous edition are reproduced in color and enhanced with additional explanatory detail. With a dedicated focus on polymeric materials, the book includes details on the experimental techniques that are used to characterize the materials, particularly in cases of failure. Finally, the book has information on the fabrication of polymer devices, as manufacturing flaws often play a role in failure. Demonstrates the latest forensic engineering techniques used in the investigation of failed polymer components Presents detailed case studies that illustrate different types of failure in polymer components, fittings, and medical devices Examines the role of manufacturing in product failure with an overview of faults recognized in methods, design, and material selection Provides an integrated approach to polymer failures that covers everything from basic materials properties, through to the experimental techniques required to study them

Bioresorbable Polymers and their Biomedical Applications

Bioresorbable Polymers and their Biomedical Applications Book
Author : Declan M Devine
Publisher : Smithers Rapra
Release : 2017-04-10
ISBN : 1911088092
Language : En, Es, Fr & De

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Book Description :

Bioresorbable or biodegradable polymers are commonly used in various biomedical applications. The application of bioresorbable polymers in the biomedical sector has been widely exploited by immobilising suturing thread with an analgesic or antibacterial drugs, and the development of bioresorbable vascular scaffolds, wound-healing and intravenous drug-delivery devices. Furthermore, biodegradable polymers have been investigated as a replacement for metallic orthopaedic devices due to their precise control of material composition and microstructure. These polymers are eliminated from the body via dissolution, assimilation and excretion through metabolic pathways. The hydrolysing process breaks down the polymer into smaller units and its degradation products are excreted by means of the citric acid cycle or by direct renal excretion with no residual side effects.Processing of bioresorbable implants can be achieved via conventional polymer processing methods such as extrusion, injection and compressing moulding, solvent spinning or casting. However, special consideration must be given when processing these materials because heat can cause a reduction in molecular weight due to the hydrolysing of bonds. In addition, overheating can depolymerise the polymer and, as a result, monomers can have a plasticising effect on the polymer. Recently, alternative approaches utilising rapid prototyping and micro-/nanofabrication processes have been employed.This book addresses these issues and highlights recent advances in the biomedical field that have being enabled by the use of biodegradable polymers. This book is designed as a reference guide for academic researchers utilising biodegradable polymers in a range of areas from tissue engineering to controlled release of active pharmaceuticals, through to industry-based processors of biodegradable polymers.

Recycled Plastic Biocomposites

Recycled Plastic Biocomposites Book
Author : Md Rezaur Rahman,Muhammad Khusairy Bin Bakri
Publisher : Woodhead Publishing
Release : 2022-01-25
ISBN : 0323886450
Language : En, Es, Fr & De

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Book Description :

Recycled plastic biocomposites have attracted widespread attention from both researchers and manufacturers due to the significant improvements in their physico-mechanical, thermal, rheological, and barrier properties when compared to conventional materials, as well as their potential regarding commercialization and zero waste. Recycled Plastic Biocomposites presents the latest information on recycled polymers, textiles, pulp and paper, wood plastic, rubber waste plastic, and micro and nano effects of recycled plastic waste resources that have great potential as reinforcement materials in composites because they are non-toxic, inexpensive, biodegradable, cost-effective, and available in large amounts. Recycled plastic biocomposites are now starting to be deployed in a broad range of materials applications due to their advantages over petroleum-based materials. Currently, there are no limits to the possibility of their applications. They also have exceptional sustainable and biodegradable properties when compared to conventional materials such as polymers and composites. Recycled Plastic Biocomposites reviews the latest research advances on recycled plastic-based biocomposites, including thermoplastic, thermoset, rubber, and foams. In addition, the book covers critical assessments on the economics of recycled plastic, including a cost-performance analysis that discusses its strengths and weaknesses as a reinforcement material. The huge potential applications of recycled plastic in industry are also explored in detail with respect to low cost, recyclable and biodegradable properties, and the way they can be applied to the automotive, construction, and packaging industries. The life cycles of both single and hybrid recycled plastic-based polymer composites and biocomposites are also discussed in detail. From the viewpoint of recycled plastic-based polymer composites, the book covers not only the well-known role of recycled polymers and composites, but also advanced materials produced from micro-, nano-, and pico-scale fillers that achieve better physical, mechanical, morphological, and thermal properties. This book will be an essential reference resource for academic and industrial researchers, materials scientists, and those working in polymer science and engineering, chemical engineering, manufacturing, and biocomposites. Places an emphasis on micro-, nano-, and pico-scale fillers that significantly improve properties. Discusses the most suitable fabrication methods, properties, and applications. Features critical assessments on the economics of recycled plastic, including a cost-performance analysis that reviews its strengths and weaknesses as a reinforcement material.

Medical Devices

Medical Devices Book
Author : Seeram Ramakrishna,Lingling Tian,Charlene Wang,Susan Liao,Wee Eong Teo
Publisher : Woodhead Publishing
Release : 2015-08-18
ISBN : 0081002912
Language : En, Es, Fr & De

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Book Description :

Medical Devices and Regulations: Standards and Practices will shed light on the importance of regulations and standards among all stakeholders, bioengineering designers, biomaterial scientists and researchers to enable development of future medical devices. Based on the authors’ practical experience, this book provides a concise, practical guide on key issues and processes in developing new medical devices to meet international regulatory requirements and standards. Provides readers with a global perspective on medical device regulations Concise and comprehensive information on how to design medical devices to ensure they meet regulations and standards Includes a useful case study demonstrating the design and approval process

Materials for Medical Application

Materials for Medical Application Book
Author : Robert B. Heimann
Publisher : Walter de Gruyter GmbH & Co KG
Release : 2020-08-24
ISBN : 3110619318
Language : En, Es, Fr & De

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Book Description :

This book gives an introduction to the highly interdisciplinary field of biomaterials. It concisely summarizes properties, synthesis and modification of materials such as metals, ceramics, polymers or composites. Characterization, in vitro and in vivo testing as well as a selection of various applications are also part of this inevitable guide.

Regulatory Affairs for Biomaterials and Medical Devices

Regulatory Affairs for Biomaterials and Medical Devices Book
Author : Stephen F. Amato,Robert M. Ezzell Jr
Publisher : Elsevier
Release : 2014-10-27
ISBN : 0857099205
Language : En, Es, Fr & De

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Book Description :

All biomaterials and medical devices are subject to a long list of regulatory practises and policies which must be adhered to in order to receive clearance. This book provides readers with information on the systems in place in the USA and the rest of the world. Chapters focus on a series of procedures and policies including topics such as commercialization, clinical development, general good practise manufacturing and post market surveillance. Addresses global regulations and regulatory issues surrounding biomaterials and medical devices Especially useful for smaller companies who may not employ a full time vigilance professional Focuses on procedures and policies including risk management, intellectual protection, marketing authorisation, university patent licenses and general good practise manufacturing

Joining and Assembly of Medical Materials and Devices

Joining and Assembly of Medical Materials and Devices Book
Author : Y N Zhou,M D Breyen
Publisher : Elsevier
Release : 2013-05-31
ISBN : 0857096427
Language : En, Es, Fr & De

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Book Description :

As medical devices become more intricate, with an increasing number of components made from a wide range of materials, it is important that they meet stringent requirements to ensure that they are safe to be implanted and will not be rejected by the human body. Joining and assembly of medical materials and devices provides a comprehensive overview of joining techniques for a range of medical materials and applications. Part one provides an introduction to medical devices and joining methods with further specific chapters on microwelding methods in medical components and the effects of sterilization on medical materials and welded devices. Part two focuses on medical metals and includes chapters on the joining of shape memory alloys, platinum (Pt) alloys and stainless steel wires for implantable medical devices and evaluating the corrosion performance of metal medical device welds. Part three moves on to highlight the joining and assembly of medical plastics and discusses techniques including ultrasonic welding, transmission laser welding and radio frequency (RF)/dielectric welding. Finally, part four discusses the joining and assembly of biomaterial and tissue implants including metal-ceramic joining techniques for orthopaedic applications and tissue adhesives and sealants for surgical applications. Joining and assembly of medical materials and devices is a technical guide for engineers and researchers within the medical industry, professionals requiring an understanding of joining and assembly techniques in a medical setting, and academics interested in this field. Introduces joining methods in medical applications including microwelding and considers the effects of sterilization on the resulting joints and devices Considers the joining, assembly and corrosion performance of medical metals including shape memory alloys, platinum alloys and stainless steel wires Considers the joining and assembly of medical plastics including multiple welding methods, bonding strategies and adhesives

Sterilisation of Biomaterials and Medical Devices

Sterilisation of Biomaterials and Medical Devices Book
Author : Sophie Lerouge,Anne Simmons
Publisher : Elsevier
Release : 2012-09-27
ISBN : 0857096265
Language : En, Es, Fr & De

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Book Description :

The effective sterilisation of any material or device to be implanted in or used in close contact with the human body is essential for the elimination of harmful agents such as bacteria. Sterilisation of biomaterials and medical devices reviews established and commonly used technologies alongside new and emerging processes. Following an introduction to the key concepts and challenges involved in sterilisation, the sterilisation of biomaterials and medical devices using steam and dry heat, ionising radiation and ethylene oxide is reviewed. A range of non-traditional sterilisation techniques, such as hydrogen peroxide gas plasma, ozone and steam formaldehyde, is then discussed together with research in sterilisation and decontamination of surfaces by plasma discharges. Sterilisation techniques for polymers, drug-device products and tissue allografts are then reviewed, together with antimicrobial coatings for ‘self-sterilisation’ and the challenge presented by prions and endotoxins in the sterilisation of reusable medical devices. The book concludes with a discussion of future trends in the sterilisation of biomaterials and medical devices. With its distinguished editors and expert team of international contributors, Sterilisation of biomaterials and medical devices is an essential reference for all materials scientists, engineers and researchers within the medical devices industry. It also provides a thorough overview for academics and clinicians working in this area. Reviews established and commonly used technologies alongside new and emerging processes Introduces and reviews the key concepts and challenges involved in sterilisation Discusses future trends in the sterilisation of biomaterials and medical devices