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Drug Allergy Testing

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Drug Allergy Testing

Drug Allergy Testing Book
Author : David Khan,Aleena Banerji
Publisher : Elsevier Health Sciences
Release : 2017-07-05
ISBN : 0323497071
Language : En, Es, Fr & De

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Book Description :

With a focus on improving diagnosis and treatment, Drug Allergy Testing is your new go-to resource for understanding various drug allergies and testing methods, the epidemiology of and economic impact of drug allergies, and new drug and allergy developments. Features a wealth of up-to-date information for allergists, immunologists, and primary care physicians who diagnose and treat patients with drug allergies and hypersensitivity. Covers the basics of drug allergy evaluation and management as well as specific drugs including antibiotics, ASA/NSAIDs, chemotherapeutic agents and monoclonal antibodies.

Drug Allergy Testing

Drug Allergy Testing Book
Author : David Khan,Aleena Banerji
Publisher : Elsevier
Release : 2017-07-31
ISBN : 9780323485517
Language : En, Es, Fr & De

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Book Description :

With a focus on improving diagnosis and treatment, Drug Allergy Testing is your new go-to resource for understanding various drug allergies and testing methods, the epidemiology of and economic impact of drug allergies, and new drug and allergy developments. Features a wealth of up-to-date information for allergists, immunologists, and primary care physicians who diagnose and treat patients with drug allergies and hypersensitivity. Covers the basics of drug allergy evaluation and management as well as specific drugs including antibiotics, ASA/NSAIDs, chemotherapeutic agents and monoclonal antibodies.

Monographs in Contact Allergy Volume 4

Monographs in Contact Allergy  Volume 4 Book
Author : Anton C. de Groot
Publisher : CRC Press
Release : 2022-03-09
ISBN : 1000549917
Language : En, Es, Fr & De

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Book Description :

This fourth volume in an exciting and detailed series on contact allergens and drug allergy provides monographs of all 507 systemic drugs which have caused delayed-type cutaneous drug hypersensitivity reactions and/or occupational allergic contact dermatitis. The monographs present: Identification section; Occupational allergic contact dermatitis; and Cutaneous adverse drug reactions from systemic drugs caused by type IV (delayed-type) hypersensitivity, as shown by positive patch tests (e.g. maculopapular eruption, acute generalized exanthematous pustulosis [AGEP], symmetrical drug-related intertriginous and flexural exanthema [SDRIFE], fixed drug eruption, drug reaction with eosinophilia and systemic symptoms [DRESS], and photosensitivity). Separate chapters present an overview of the spectrum of allergic cutaneous drug reactions, diagnostic tests, immediate contact reactions (contact urticaria), and systemic drugs that have acquired delayed-type hypersensitivity only by cross-reactivity. Key Features: Presents monographs of all known systemic drugs which have caused delayed allergic cutaneous drug reactions and/or occupational allergic contact dermatitis Provides an extensive literature review of relevant topics of allergenic systemic drugs, part of which is hard or impossible to find in database searches Identifies IUPAC names, synonyms, CAS and EC numbers, structural and chemical formulas, Merck Index monographs, and advises on patch testing Presents immediate contact reactions (contact urticaria) from systemics drugs and delayed-type hypersensitivity in drugs caused only by cross-reactivity Covers an extensive amount of information to benefit dermatologists, allergists, and all others interested in drug allergy

Middleton s Allergy

Middleton s Allergy Book
Author : Anonim
Publisher : Unknown
Release : 2009
ISBN : 9780323056595
Language : En, Es, Fr & De

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Book Description :

This best-selling resource has a worldwide reputation as the leader in its field. Focusing on human immunology and biology, while also reporting on scientific experimentation and advancement, it provides comprehensive coverage of state-of-the-art basic science as well as authoritative guidance on the practical aspects of day-to-day diagnosis and management. This new edition includes 700 full-color illustrations and a new, more accessible format to make finding information a snap for the busy practitioner. And this Expert Consult Edition offers online access to the complete contents of the 2-volume set, fully searchable, and much more. Includes a glossary of allergy and immunology for quick and easy reference. Contains keypoints and clinical pearls highlighted to find important information quickly. links to useful online resources both for you and for your patients. Offers contributions from hundreds of international authorities for world-class expertise in overcoming any clinical challenge.

Practical Implementation of an Antibiotic Stewardship Program

Practical Implementation of an Antibiotic Stewardship Program Book
Author : Tamar F. Barlam,Melinda M. Neuhauser,Pranita D. Tamma,Kavita K. Trivedi
Publisher : Cambridge University Press
Release : 2018-04-30
ISBN : 1107166179
Language : En, Es, Fr & De

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Book Description :

This practical reference guide from experts in the field details why and how to establish successful antibiotic stewardship programs.

Zinc Signaling

Zinc Signaling Book
Author : Toshiyuki Fukada,Taiho Kambe
Publisher : Springer Nature
Release : 2019-12-13
ISBN : 9811505578
Language : En, Es, Fr & De

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Book Description :

This book, now in an extensively revised second edition, describes the crucial role of zinc signaling in biological processes on a molecular and physiological basis. Global leaders in the field review the latest knowledge, including the very significant advances in understanding that have been achieved since publication of the first edition. Detailed information is provided on all the essentials of zinc signaling, covering molecular aspects and the roles of zinc transporters, the zinc sensing receptor, and metallothioneins. Detection techniques for zinc signals, involving genetically encoded and chemical probes, are also described. The critical contributions of the zinc signal in maintaining health and the adverse consequences of any imbalance in the signal are then thoroughly addressed. Here, readers will find up-to-date information on the significance of the zinc signal in a wide range of conditions, including cardiovascular disorders, neurodegenerative diseases, diabetes, autoimmune diseases, inflammatory conditions, skin disease, osteoarthritis, and cancer. The book will be of value for researchers, clinicians, and advanced students.

Drug Hypersensitivity

Drug Hypersensitivity Book
Author : Werner J. Pichler
Publisher : Karger Medical and Scientific Publishers
Release : 2007-01-01
ISBN : 3805582692
Language : En, Es, Fr & De

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Book Description :

Approaches the phenomenon of drug hypersensitivity in a comprehensive manner. Besides epidemiological aspects, it addresses the immunological mechanisms underlying these complicated reactions which go far beyond the IgE-mediated drug allergies also considered in this book. The book also covers clinical manifestations and new diagnostic methods, and introduces some recetly established animal models. Many topics are treated from multiple perspectives, and the 33 chapters are thoroughly cross-referenced.

Drug Allergy

Drug Allergy Book
Author : Brian A. Baldo,Nghia H. Pham
Publisher : Springer Science & Business Media
Release : 2013-07-02
ISBN : 146147261X
Language : En, Es, Fr & De

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Book Description :

The variety of chemically diverse pharmacological agents administered to patients is large and continues to expand and with every new drug released, there is always potential for adverse reactions, some of them allergic. With its roots in immunology and pharmacology, the science of drug allergy is becoming better understood and applied as its importance is increasingly recognized throughout the many branches of medicine. Drug Allergy: Clinical Aspects, Diagnosis, Mechanisms, Structure-Activity Relationships sheds new light on this field. Comprehensive in design, this authoritative title identifies the most important culprit drugs implicated in immediate and delayed drug hypersensitivities and offers up-to-date information on classifications, diagnoses, underlying mechanisms and structure-activity relationships. Chapters dealing with the molecular and cellular mechanisms of drug hypersensitivities, non-immune-mediated sensitivities and diagnostic methods are presented as introductory material for in-depth treatises on the β-lactam antibiotics, other antibiotics and antimicrobials, drugs used in anesthesia and surgery, opioid analgesics, corticosteroids, monoclonal antibodies and other biologics, drugs used in chemotherapy, proton pump inhibitors, iodinated and gadolinium-based contrast media and non-steroidal anti-inflammatory drugs. In addition to being of immense value to clinicians, other health care professionals and researchers, this title will prove invaluable for those taking undergraduate and graduate courses in science and will also serve as a useful text for students of medicine, pharmacy, nursing and dentistry.

Textbook of Allergy for the Clinician

Textbook of Allergy for the Clinician Book
Author : Pudupakkam K. Vedanthan,Harold S. Nelson,Shripad N. Agashe,Mahesh P A,Rohit Katial
Publisher : CRC Press
Release : 2016-04-19
ISBN : 1466598344
Language : En, Es, Fr & De

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Book Description :

This well-illustrated book synthesizes all aspects of allergy, asthma, and related fields such as aerobiology and immunology. Appropriate for allergy practitioners and medical students seeking the latest information on allergy and asthma, it covers aeroallergens and their source plants all over the world.The book focuses on allergies caused by pollen and environmental pollution as well as skin disorders stemming from latex allergies. It contains the latest methods of diagnosis and treatment of allergy and asthma releveant to applied clinical immunology.

Indoor Allergens

Indoor Allergens Book
Author : National Research Council,Institute of Medicine,Committee on the Health Effects of Indoor Allergens
Publisher : National Academies Press
Release : 1993-02-01
ISBN : 0309048311
Language : En, Es, Fr & De

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Book Description :

More than 50 million Americans, one out of five, suffer from hay fever, asthma, and other allergic diseases. Many of these conditions are caused by exposure to allergens in indoor environments such as the house, work, and school--where we spend as much as 98 percent of our time. Developed by medical, public health, and engineering professionals working together, this unique volume summarizes what is known about indoor allergens, how they affect human health, the magnitude of their effect on various populations, and how they can be controlled. The book addresses controversies, recommends research directions, and suggests how to assist and educate allergy patients, as well as professionals. Indoor Allergens presents a wealth of information about common indoor allergens and their varying effects, from significant hay fever to life-threatening asthma. The volume discusses sources of allergens, from fungi and dust mites to allergenic chemicals, plants, and animals, and examines practical measures for their control. Indoor Allergens discusses how the human airway and immune system respond to inhaled allergens and assesses patient testing methods, covering the importance of the patient's medical history and outlining procedures and approaches to interpretation for skin tests, in vitro diagnostic tests, and tests of patients' pulmonary function. This comprehensive and practical volume will be important to allergists and other health care providers; public health professionals; specialists in building design, construction, and maintenance; faculty and students in public health; and interested allergy patients.

Middleton s Allergy Essentials E Book

Middleton s Allergy Essentials E Book Book
Author : Robyn E O'Hehir,Stephen T Holgate,Aziz Sheikh
Publisher : Elsevier Health Sciences
Release : 2015-12-09
ISBN : 0323392733
Language : En, Es, Fr & De

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Book Description :

For decades, health care practitioners have relied on Middleton’s Allergy as their go-to reference for comprehensive information on allergic disorders. Now Middleton’s Allergy Essentials, by Drs. Robyn E. O'Hehir, Stephen T. Holgate, and Aziz Sheikh, offers a concise resource that’s both easily accessible and highly authoritative. Perfect for clinicians in primary and secondary care settings, this practical volume covers what is most useful in your daily practice, with a strong emphasis on disease diagnosis and management. A practical approach to evaluation, differential diagnosis, and treatment of allergic disorders, focused specifically on what the non-specialist needs to know for everyday practice. Each chapter begins with a handy summary of key concepts to help you quickly identify important information. Coverage of today’s hot topics includes asthma, drug allergies, food allergies and gastrointestinal disorders, anaphylaxis, atopic dermatitis, and allergic contact dermatitis. Concise sections on mechanisms are included where relevant, keeping you up to date with this rapidly evolving field. Authored by the same internationally recognized experts that produce Middleton’s Allergy, the definitive text in the field. Ideal for physicians, residents, general and family practitioners, nurse practitioners, primary care doctors, hospitalists, general internists – anyone who is called upon to make effective diagnostic and treatment decisions regarding allergic disorders.

Scratch patch and Patch Testing in Drug Allergy

Scratch patch and Patch Testing in Drug Allergy Book
Author : Katrin Hug
Publisher : Unknown
Release : 2003
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Scratch patch and Patch Testing in Drug Allergy book written by Katrin Hug, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Clinical Allergy

Clinical Allergy Book
Author : Gerald W. Volcheck
Publisher : Springer Science & Business Media
Release : 2009-03-02
ISBN : 9781597453158
Language : En, Es, Fr & De

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Book Description :

Allergic diseases affect nearly one-fourth of the population and cause or contribute to significant chronic illness. Allergic diseases are common and are seen by a wide variety of health care providers. In Clinical Allergy: Diagnosis and Management, the author provides a practical clinical overview for the common disorders encountered in the specialty of Allergy. Designed to be easily readable and to provide clinically applicable information for both the nonallergist and allergist, the intent is to unravel the mystery of allergy. The introductory chapters focus on the human immune response, environmental allergens, and the different types of allergy testing. The subsequent chapters focus on the common allergic conditions seen in the office or clinic, including rhinitis and rhinosinusitis, allergic eye disease, asthma, urticaria and angioedema, atopic and contact dermatitis, drug allergy, food allergy, anaphylaxis, and stinging insect allergy. "Cross-talk" between chapters helps show the interrelationships among the various allergic disorders. The chapters begin with a review of pathophysiologic mechanisms and then consider a clinically structured approach to diagnosis and management of the disorders. In addition to pharmacologic treatment, the importance of nonpharmacologic management and patient education is emphasized. At the end of each chapter, clinical vignettes highlight the daily management of the allergic patient. Clinical Allergy: Diagnosis and Management, provides a logical framework for the evaluation and management of allergic disorders in patients.

Monographs in Contact Allergy Volume 3

Monographs in Contact Allergy  Volume 3 Book
Author : Anton C. de Groot
Publisher : CRC Press
Release : 2021-02-16
ISBN : 100036786X
Language : En, Es, Fr & De

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Book Description :

This third volume in an exciting and detailed series on contact allergens provides monographs of all 384 topical drugs which have caused contact allergy/allergic contact dermatitis. The monographs present: Identification section; Contact allergy (general population, patients with dermatitis, case reports and case series); Cross-reactions; Patch test sensitization; Photocontact allergy; and Immediate contact reactions (contact urticaria). Separate chapters present an overview of all aspects of allergic contact dermatitis to topical drugs, contact allergy to non-drug ingredients in topical pharmaceuticals and a preview of delayed-type allergy to systemic drugs (to be discussed in Volume 4). Key Features: Presents monographs of all known topical drugs which have caused contact allergy/allergic contact dermatitis Provides a full literature review of relevant topics of allergenic topical drugs Identifies IUPAC names, synonyms, CAS and EC numbers, structural and chemical formulas, Merck Index monographs, and advises on patch testing Presents non-drug allergens in topical pharmaceuticals Covers an extensive amount of information to benefit dermatologists, allergists, and all others interested in drug allergy

Drug Allergy

Drug Allergy Book
Author : Brian A. Baldo,Nghia H. Pham
Publisher : Springer Nature
Release : 2020-12-08
ISBN : 3030517403
Language : En, Es, Fr & De

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Book Description :

The second edition of this book spans the broad range of modern therapeutic drugs, from small molecules to biologic recombinant proteins. It offers a comprehensive review of the classification and description of different drug-induced systemic and cutaneous hypersensitivities; an up-to-date coverage of individual culprit drugs in each group of therapeutics; the diagnosis and mechanisms of reactions; and important structure-activity relationships. New content expands to two areas of drug allergy that have recently experienced explosive growth: biological therapies and new targeted chemotherapies. Other new and expanded chapters address antimicrobials; drugs used in anesthesia and surgery; opioids; non-targeted anti-cancer drugs; vaccines; and newly understood reaction mechanisms. This new edition includes photographs of a wide variety of cutaneous manifestations that will be of use to other clinicians as well as allergists and dermatologists. In addition to its wide clinical emphasis, the book’s mechanistic and structure-activity detail will provide valuable background for researchers and investigators in universities, medical research institutes, drug companies, and regulatory agencies. The second edition of Drug Allergy is an essential reference for practitioners across the medical disciplines from specialist clinicians, surgeons, GPs, residents, and medical students to nurses, pharmacists, dentists, and those taking undergraduate and graduate courses in the biomedical sciences.

Novel Advances in Allergy Diagnosis and Treatment

Novel Advances in Allergy Diagnosis and Treatment Book
Author : Simon Blank,Christiane Hilger
Publisher : Frontiers Media SA
Release : 2021-12-20
ISBN : 2889668495
Language : En, Es, Fr & De

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Book Description :

Download Novel Advances in Allergy Diagnosis and Treatment book written by Simon Blank,Christiane Hilger, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Cutaneous Drug Hypersensitivity

Cutaneous Drug Hypersensitivity Book
Author : Andreas J. Bircher,Howard I. Maibach,Knut Brockow,Annick Barbaud
Publisher : Springer Nature
Release : 2022-08-10
ISBN : 3030827437
Language : En, Es, Fr & De

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Book Description :

This book covers all aspects of hypersensitivity to drugs, providing practical information for non-specialist physicians as well as addressing issues of interest to practitioners in different specialties and presenting the expert knowledge required by specialist allergists and immunologists. The opening, general section discusses basics such as clinical manifestations, histopathology, mechanisms, risk factors, drug hypersensitivity in particular populations, and the full range of diagnostic methods. The second part of the book provides concise information on the most important drug classes and guides the reader on how to proceed when patients present with a suspected reaction. For each drug class, the current level of evidence for use of the different diagnostic tools, including skin tests, provocation tests, and in vitro tests, is clarified, and management options, outlined. The inclusion of helpful tables and algorithms is designed to aid in decision making. Drug hypersensitivity is among the more complex allergological issues, and this book will meet the needs of general practitioners, internists, and specialists.

Allergic Reactions to Drugs

Allergic Reactions to Drugs Book
Author : Alain L. de Weck,H. Bundgaard
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3642690882
Language : En, Es, Fr & De

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Book Description :

According to most studies, allergic reactions represent 35%-50% of all untoward reactions to drugs, yet the pharmacological literature concerning the clinical aspects, diagnosis, and pathophysiological mechanisms of drug allergy is markedly less extensive than reports dealing with the toxicological or pharmacological effects of drugs. The main reasons for this state of affairs may be on the one hand that until a few years ago the pathophysiological mechanisms of the various types of allergic reactions were not well understood, and on the other hand that objective diagnosis of a drug allergy is still fraught with serious difficulties. Drug allergy is still an unpopular topic for most allergologists and pharmacologists; this is reflected by the fact that despite their frequency, allergic reactions to drugs still occupy a relatively small proportion of space in most pharmacology handbooks and in classical books devoted to the side effects of drugs. There has recently been considerable progress in research into the immunologi cal and pathophysiological events occurring in allergic reactions, and on that basis investigations of various drug allergies have also yield~d new objective findings. Consequently, it was natural to attempt a review of the most frequent and important drug allergies in the form of a handbook. We originally intended to present a comprehensive review of all drug allergies, but the realization of this goal soon became more difficult than we had at first imagined.

The New Allergy Solution

The New Allergy Solution Book
Author : Dr. Clifford Bassett
Publisher : Penguin
Release : 2017-03-21
ISBN : 1101980605
Language : En, Es, Fr & De

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Book Description :

One of America’s top allergy doctors offers a revolutionary, full-body approach to diagnosing, preventing, and treating allergies—in many cases, for good. Millions of Americans currently suffer from allergies, and the rate is growing. Climate change, globalization, air pollution, and oversanitization of the environment in the early years of life are just a few of the causes that, taken together, have introduced new allergens into our environment that are wreaking havoc and causing needless suffering. This “new allergen marketplace” requires a new allergy solution. According to Dr. Clifford W. Bassett, traditional remedies focus on treating symptoms but leave allergy sufferers vulnerable to continued bouts of misery. Dr. Bassett argues that when we consider a person’s genetics, environment, and overall health, we can more effectively identify—and take appropriate action to forestall—symptoms before they even begin. For the first time, Dr. Bassett presents the unique, integrative approach he’s used in his Manhattan offices for two decades to vanquish allergy symptoms for countless individuals. In addition to explaining what allergy is (and isn’t) and identifying key triggers—from nuts to gluten to the nickel commonly used in cell phones—Dr. Bassett offers both medical and nonmedical alternatives to treatment, and specific, proactive steps to protect against common allergens. Allergens are here to stay, but with The New Allergy Solution, your life need no longer be ruled and ruined by allergy. The New Allergy Solution strives to enhance your well-being through strategies for a greater sense of control, giving you more freedom to do what you love.

Improving Antibiotic Stewardship

Improving Antibiotic Stewardship Book
Author : Yara Moussa
Publisher : Unknown
Release : 2019
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

"Approximately 10% of individuals claim penicillin allergy based on vague or remote histories and are permanently labeled [beta]-lactam allergic. These individuals receive suboptimal non-[beta]-lactams for intraoperative prophylaxis prolonging operations and experience negative clinical outcomes. Clarifying penicillin allergic status is thus of major importance. This thesis examines pre-operative allergy assessments including drug allergic history, penicillin skin testing and/or oral challenge on selection of perioperative antibiotics. It also examines the effectiveness of communicating the drug allergy patient de-labeling status to the surgical team. Patients referred from April 1st, 2015 to March 31st, 2017 for suspected [beta]-lactam hypersensitivity were studied. Those having pre-operative allergy assessments within 6 months of surgery were analysed. Data collected included age, gender, drug allergy history, drug allergy skin testing, oral challenges along with the type of surgery, time of operating room entry, incision start time and intraoperative antibiotics.. Of the 194 patients evaluated, four were [beta]-lactam allergic on skin testing. Among the remaining 190 skin test negative patients, 146 were [beta]-lactam challenged. Only 5% of these reacted and considered [beta]-lactam allergic. Cefazolin became the perioperative antibiotic of choice for the remaining 77% of non-allergic patients requiring antibiotic prophylaxis. Only 5 of the confirmed [beta]-lactam allergic patients received intraoperative vancomycin. Patients not prescribed vancomycin saved on average 22 minutes in operative time. Among all 194 evaluated patients, 35 were given suboptimal alternative antibiotics perioperatively. These included 16 that tested negative for [beta]-lactam allergy yet prescribed vancomycin and 17 that received clindamycin. The 2 remaining tested positive for [beta]-lactam allergy and were erroneously given cefazolin. The suboptimal antibiotic use stemmed from poor reporting of the allergy evaluations. Factors included delays in transmitting the results from the allergy clinic in 12 patients, 15 patients reported being [beta]-lactam allergic to the surgical team at the time of surgery despite having tested negative and the remaining 8 had no clear reason for being prescribed an alternative antibiotic. To identify causes of miscommunication, a questionnaire survey was sent to allergists, surgeons and anesthesiologists.. Results of the survey revealed that surgeons and anesthesiologists prefer direct and clear statements like "the patient is not allergic to penicillin" or "can be administered cefazolin"; while allergists preferred qualifying statements such as "at this time the patient is not allergic to penicillin, based on skin testing, oral challenge and clinical assessment". In summary, comprehensive penicillin allergy evaluation successfully de-labeled 94.3% of patients referred for pre-operative [beta]-lactam allergy evaluation. Vancomycin was used only in five surgeries (3%) (those truly penicillin allergic) and cefazolin was subsequently prescribed for 120/155 (77.4%) of the de-labeled patients given antibiotics.. The reduced use of vancomycin minimized delays in initiation of incision time, thus improving operative efficiency. Multiple issues indicating poor communication were identified partially explaining the suboptimal antibiotic use and signifying a need for consensus statements in drug allergy reporting. The main limitation of the study was that pre-operative allergy referrals were not mandatory, thus not all pre-operative patients claiming to be [beta]-lactam allergic were captured." --