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Diseases Of The Nervous System

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Diseases of the Nervous System

Diseases of the Nervous System Book
Author : Harald Sontheimer
Publisher : Elsevier
Release : 2021-05-20
ISBN : 0128213965
Language : En, Es, Fr & De

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Book Description :

The study of the brain continues to expand at a rapid pace providing fascinating insights into the basic mechanisms underlying nervous system illnesses. New tools, ranging from genome sequencing to non-invasive imaging, and research fueled by public and private investment in biomedical research has been transformative in our understanding of nervous system diseases and has led to an explosion of published primary research articles. Diseases of the Nervous System, Second Edition, summarizes the current state of basic and clinical knowledge for the most common neurological and neuropsychiatric conditions. In a systematic progression, each chapter covers either a single disease or a group of related disorders ranging from static insults to primary and secondary progressive neurodegenerative diseases, neurodevelopmental illnesses, illnesses resulting from nervous system infection and neuropsychiatric conditions. Chapters follow a common format and are stand-alone units, each covering disease history, clinical presentation, disease mechanisms and treatment protocols. Dr. Sontheimer also includes two chapters which discuss common concepts shared among the disorders and how new findings are being translated from the bench to the bedside. In a final chapter, he explains the most commonly used neuroscience jargon. The chapters address controversial issues in current day neuroscience research including translational research, drug discovery, ethical issues, and the promises of personalized medicine. This new edition features new chapters on Pain and Addiction to highlight the growing opioid crisis and the ethical issue of prescriptions drug abuse. This book provides an introduction for course adoption and an introductory tutorial for students, scholars, researchers and medical professionals interested in learning the state of the art concerning our understanding and treatment of diseases of the nervous system. Each chapter includes suggested further readings and/or journal club recommendations. 2016 PROSE Award winner of the Best Textbook Award in Biological and Life Sciences Provides a focused tutorial introduction to the core diseases of the nervous system Includes comprehensive introductions to Stroke, Epilepsy, Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, ALS, Head and Spinal Cord Trauma, Multiple Sclerosis, Brain Tumors, Depression, Schizophrenia and many other diseases of the nervous system Covers more than 40 diseases from the foundational science to the best treatment protocols Includes discussions of translational research, drug discovery, personalized medicine, ethics, and neuroscience New Edition features two new chapters on Pain and Addiction

OCT and Imaging in Central Nervous System Diseases

OCT and Imaging in Central Nervous System Diseases Book
Author : Andrzej Grzybowski,Piero Barboni
Publisher : Springer Nature
Release : 2020-01-01
ISBN : 3030262693
Language : En, Es, Fr & De

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Book Description :

The second edition of OCT and Imaging in Central Nervous System Diseases offers updated state-of-the-art advances using optical coherence tomography (OCT) regrading neuronal loss within the retina. Detailed information on the OCT imaging and interpretation is provided for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury. Covering disorders like multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, intracranial hypertension, Friedreich’s ataxia, schizophrenia, hereditary optic neuropathies, glaucoma, and amblyopia, readers will given insights into effects on the retina and the and optic nerve. Individual chapters are also devoted to OCT technique, new OCT technology in neuro-ophthalmology, OCT and pharmacological treatment, and the use of OCT in animal models. Similar to the first edition, this book is an excellent and richly illustrated reference for diagnosis of many retinal diseases and monitoring of surgical and medical treatment. OCT allows to study vision from of the retina to the optic tracts. Retinal axons in the retinal nerve fiber layer (RNFL) are non-myelinated until they penetrate the lamina cribrosa. Hence, the RNFL is an ideal structure for visualization of any process of neurodegeneration, neuroprotection, or regeneration. By documenting the ability of OCT to provide key information on CNS diseases, this book illustrates convincingly that the eye is indeed the “window to the brain”.

Inflammatory Disorders of the Nervous System

Inflammatory Disorders of the Nervous System Book
Author : Alireza Minagar,J. Steven Alezander
Publisher : Springer Science & Business Media
Release : 2007-10-28
ISBN : 1592599052
Language : En, Es, Fr & De

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Book Description :

A cutting-edge review of the fundamental biological principles underlying the more common inflammatory disorders of the nervous system. The authors provide extensive updates on the latest findings concerning the mechanisms of inflammation and introduce such new concepts and methodologies as "endothelial and leukocyte microparticles" and "gene microarray technology" to help explain important links between the central nervous system (CNS) and general inflammatory processes. Among the diseases examined from an inflammatory perspective are multiple sclerosis, acute disseminated encephalomyelitis, optic neuritis, transverse myelitis, CNS vasculitis, neuropsychiatric systemic lupus erythematosis, Alzheimer's disease, and Parkinson's disease. The role of the immune system in neuroinflammation is also explored in such disorders as neurosarcoidois, HIV-Associated dementia, and HTLV-associated neurological disorders.

Diseases of the Nervous System

Diseases of the Nervous System Book
Author : Arthur K. Asbury,Guy M. McKhann,W. Ian McDonald,Peter J. Goadsby,Justin C. McArthur
Publisher : Cambridge University Press
Release : 2002-11-11
ISBN : 9780521793513
Language : En, Es, Fr & De

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Book Description :

The third edition of a neurology classic, this two-volume text is the most comprehensive neurology reference available. Written by leading international experts in the field, it encompasses the basic neuroscience and clinical features of the full range of neurological disorders. Disease mechanisms are reviewed comprehensively, with particular relevance to the principles of therapy. Each section, under the direction of one of the distinguished editors, is a text-within-a-text, offering the most reliable account of its topic currently available.

Neurorehabilitation for Central Nervous System Disorders

Neurorehabilitation for Central Nervous System Disorders Book
Author : Frans van der Brugge
Publisher : Springer
Release : 2017-10-27
ISBN : 3319587382
Language : En, Es, Fr & De

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Book Description :

This book describes the four most common central nervous disorders (Parkinson, stroke, dementia and multiple sclerosis) by focusing on the similarities of their symptoms. This analysis is necessary in order to determine the appropriate treatment method for individual patients. In physical therapy there are various methods available for treating patients affected by a neurological disease, yet the method presented here is the only one to include systematic interventions adapted to the patient’s needs, which are determined by means of a health situation analysis. The book offers practical and applicable information for allied health professionals seeking interventions to help patients function better in their own environment. In addition, this book features updated information on the “van der Brugge method,” focusing on a targeted program to stimulate movement in the elderly with dementia. This book will be of interest to neurologists and physiotherapist s.

Diseases of the Nervous System

Diseases of the Nervous System Book
Author : Victor Mahoney
Publisher : American Medical Publishers
Release : 2021-11-16
ISBN : 9781639272921
Language : En, Es, Fr & De

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Book Description :

Nervous system diseases are also known as neurological disorders. The nervous system consists of central and peripheral nervous systems. The brain and spinal cord together make the central nervous system. The brain is present in the skull and protected by cranium whereas the spinal cord is protected by the vertebrae. Nervous system diseases are neurological disorders that affect the functioning of the whole system. They are majorly caused by traumatic brain injury, infection in the brain or spinal cord or structural defects such as anencephaly and hypospadias. The symptoms of the nervous system diseases are pain in the face, arms, back or legs, lack of concentration, loss of feeling and constant headache. Epilepsy, spina bifida, Parkinson's disease, seizure disorders and amyotrophic lateral sclerosis are some examples of the diseases of the nervous system. This book contains some path-breaking studies related to the diseases of the nervous system. It presents researches and studies performed by experts across the globe. It is appropriate for students seeking detailed information in neurology as well as for experts.

Pediatric Demyelinating Diseases of the Central Nervous System and Their Mimics

Pediatric Demyelinating Diseases of the Central Nervous System and Their Mimics Book
Author : Emmanuelle Waubant,Timothy E. Lotze
Publisher : Springer
Release : 2017-11-07
ISBN : 331961407X
Language : En, Es, Fr & De

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Book Description :

This collection of pediatric clinical cases focus on multiple sclerosis, neuromyelitis optica, acute disseminated encephalomyelitis and mimics. Dedicated sections on diseases affecting the brain, brainstem, spinal cord and the optic nerve feature chapters that include the diagnostic work up, therapeutic management and case outcome. Typical and atypical presentations of various pediatric demyelinating diseases also emphasize therapy response and those that breakthrough on treatment. Filling a critical gap in the literature on inflammatory disorders of the central nervous system, all those that treat patients with these rare and challenging disorders will find this book extremely helpful for their daily clinical practice.

Disorders of the Autonomic Nervous System

Disorders of the Autonomic Nervous System Book
Author : Alan S. Robertson
Publisher : Routledge
Release : 2019-06-14
ISBN : 1351454811
Language : En, Es, Fr & De

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Book Description :

Disorders of the Autonomic Nervous System, the fifth volume in The Autonomic Nervous System book series, is a description of the disorders which give rise to autonomic failure and orthostatic hypotension. Each chapter is prepared by an international authority in the diagnosis and treatment of that disorder. The language and terminology are clear enough to promote understanding of the clinical problems and the underlying concepts of basic science. The most recent data, especially that derived from molecular biology, is included in the discussions of relevant diseases. Hence, the volume provides an unparalleled source of information about this area of medicine and will be helpful not just to practising clinicians but also to basic scientists researching in the field who need to familiarize themselves with the clinical problems.

Disease and Mortality in Sub Saharan Africa

Disease and Mortality in Sub Saharan Africa Book
Author : Dean T. Jamison
Publisher : World Bank Publications
Release : 2006-01-01
ISBN : 0821363980
Language : En, Es, Fr & De

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Book Description :

Current data and trends in morbidity and mortality for the sub-Saharan Region as presented in this new edition reflect the heavy toll that HIV/AIDS has had on health indicators, leading to either a stalling or reversal of the gains made, not just for communicable disorders, but for cancers, as well as mental and neurological disorders.

Metastatic Disease of the Nervous System

Metastatic Disease of the Nervous System Book
Author : David Schiff,M J Van den Bent
Publisher : Elsevier
Release : 2018-01-04
ISBN : 0444638792
Language : En, Es, Fr & De

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Book Description :

Metastatic Disease of the Nervous System, Volume 149, begins with an overview of the impact and range of direct neoplastic involvement of the central and peripheral nervous system, comprehensively reviewing all aspects of brain metastases, from clinical, radiological and neuropathological manifestations, to the roles of surgery, radiation, systemic and palliative therapy in their management, and the complications of these interventions. The clinical manifestations, diagnosis and treatment of leptomeningeal, dural, spinal epidural and plexus metastases are also covered in detail. Covers all aspects of brain metastases, from clinical, radiological and neuropathological manifestations, to the roles of surgery, radiation, systemic and palliative therapy Presents a multidisciplinary review of the evidence regarding accuracy of diagnostic testing and evidence-based reviews of therapies Addresses metastatic diseases of the nervous system for residents, fellows and clinicians in neurology and oncology

Infectious Diseases of the Nervous System

Infectious Diseases of the Nervous System Book
Author : Larry Ernest Davis,Peter G. E. Kennedy
Publisher : Butterworth-Heinemann Medical
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The primary purpose of this volume is to cover selected infections of the nervous system which are of considerable current interest, reflecting the many advances in investigations, understanding and treatment of nervous system infections. It will enable clinicians to keep abreast of recent findings and improve outcomes for many patients. The contributors provide a comprehensive discussion of each infection, including pathophysiology, clinical features, investigations, diagnosis and management. * Agents covered include bacteria, prions, viruses, and parasites * Details the newly recognized spectrum of herpes zoster encephalomyelitis and new antiviral drugs * Analyses emerging brain and spinal cord cytomegalovirus infections developing in immunocompromised patients

Aicardi s Diseases of the Nervous System in Childhood

Aicardi s Diseases of the Nervous System in Childhood Book
Author : Alexis Arzimanoglou,Anne O' Hare,Michael Johnston,Robert A. Ouvrier
Publisher : Mac Keith Press
Release : 2018-07-16
ISBN : 9781909962804
Language : En, Es, Fr & De

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Book Description :

This classic text on paediatric neurology is now in its 4th edition. Leading academics from around the world present evidence from their various areas of expertise, placing it firmly in the clinical context. Each chapter covers the basic science of the disorder and relevant genetic advances. New to this edition are chapters on fetal neurology, movement disorders, basal ganglia disease and psychogenic disorders. References at the end of each chapter are thorough, guiding the clinician to relevant further reading. The international team of editors has maintained the clinical approach of the late Jean Aicardi, which distinguishes this book from others in the field. Succinctly given, patient-focused information makes Aicardi's Diseases of Nervous System in Childhood a comprehensive yet readable resource for busy clinicians in paediatric neurology, general paediatrics, neurodisability and all the related medical disciplines.

Inflammatory Disorders of the Nervous System

Inflammatory Disorders of the Nervous System Book
Author : Alireza Minagar,J. Steven Alezander
Publisher : Springer Science & Business Media
Release : 2005-06
ISBN : 1588294242
Language : En, Es, Fr & De

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Book Description :

A cutting-edge review of the fundamental biological principles underlying the more common inflammatory disorders of the nervous system. The authors provide extensive updates on the latest findings concerning the mechanisms of inflammation and introduce such new concepts and methodologies as "endothelial and leukocyte microparticles" and "gene microarray technology" to help explain important links between the central nervous system (CNS) and general inflammatory processes. Among the diseases examined from an inflammatory perspective are multiple sclerosis, acute disseminated encephalomyelitis, optic neuritis, transverse myelitis, CNS vasculitis, neuropsychiatric systemic lupus erythematosis, Alzheimer's disease, and Parkinson's disease. The role of the immune system in neuroinflammation is also explored in such disorders as neurosarcoidois, HIV-Associated dementia, and HTLV-associated neurological disorders.

Pathogenesis of Neurodegenerative Disorders

Pathogenesis of Neurodegenerative Disorders Book
Author : Mark P. Mattson
Publisher : Springer Science & Business Media
Release : 2001
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

During the past decade many advances in our understanding of the molecular genetics and environmental factors that either cause or increase risk for age-related neurodegenerative disorders have been made. This book elucidates the fundamental mechanisms involved in neurodegenerative disorders such as Alzheimer's, Parkinson's and Huntington's diseases. In addition, mechanisms that may prevent age-related neurodegenerative disorders are also provided. Pathogenesis of Neurodegenerative disorders will provide a valuable reference to graduate students and post docs as well as to senior scientists by allowing them to integrate information on cellular and molecular mechanisms across the wide field of neurodegenerative disorders.

Neurobiology of Disease

Neurobiology of Disease Book
Author : Anonim
Publisher : Elsevier
Release : 2011-09-06
ISBN : 9780080466385
Language : En, Es, Fr & De

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Book Description :

Neurobiology of Disease is aimed at any basic scientist or clinician scientist teaching a course or conducting research on the basic science underlying the major neurological diseases. It provides an excellent overview of cutting-edge research on the fundamental disorders of the nervous system, including physiological and molecular aspects of dysfunction. The major categories of neurological disease are covered, and the chapters provide specific information about particular diseases exemplifying each of these categories. Sufficient clinical information is included to put into perspective the basic mechanisms discussed. The book assembles a world-class team of section editors and chapters written by acknowledged experts in their respective fields. Provides cutting edge information about fundamental mechanisms underlying neurological diseases Amply supplied with tables, illustrations and references Includes supporting clinical information putting the mechanisms of disease into perspective

Handbook of Innovations in Central Nervous System Regenerative Medicine

Handbook of Innovations in Central Nervous System Regenerative Medicine Book
Author : Antonio Salgado
Publisher : Elsevier
Release : 2020-06-10
ISBN : 0128180854
Language : En, Es, Fr & De

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Book Description :

Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path. Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues. Describes the basic biology and anatomy of the CNS and how injury and disease affect its balance Discusses the limitations of present therapies used in the clinics Introduces the recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies, and enabling technologies Presents successful cases of translation of basic research to first-in-human trials, along with the steps needed to follow this path

Disease Control Priorities Third Edition Volume 4

Disease Control Priorities  Third Edition  Volume 4  Book
Author : Vikram Patel,Dan Chisholm,Tarun Dua,Ramanan Laxminarayan,Mari'a Lena Medina-Mora,Theo Vos
Publisher : World Bank Publications
Release : 2016-03-10
ISBN : 1464804281
Language : En, Es, Fr & De

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Book Description :

Mental, neurological, and substance use disorders are common, highly disabling, and associated with significant premature mortality. The impact of these disorders on the social and economic well-being of individuals, families, and societies is large, growing, and underestimated. Despite this burden, these disorders have been systematically neglected, particularly in low- and middle-income countries, with pitifully small contributions to scaling up cost-effective prevention and treatment strategies. Systematically compiling the substantial existing knowledge to address this inequity is the central goal of this volume. This evidence-base can help policy makers in resource-constrained settings as they prioritize programs and interventions to address these disorders.

Metabolic and Degenerative Diseases of the Central Nervous System

Metabolic and Degenerative Diseases of the Central Nervous System Book
Author : Jorge Cervos-Navarro,Henry Urich
Publisher : Academic Press
Release : 1995-10-12
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Metabolic and Degenerative Diseases of the Central Nervous System is a comprehensive reference work that provides the neuroscience community with valuable, current, and scholarly summaries on every known degenerative disorder. Written by two world-renowned neuropathologists, the book provides an optimal basis for the understanding of metabolic and degenerative diseases of the central nervous system and presents a synthesis that serves the needs of today's investigators in neuropathology, neurology, neuroradiology, neurosurgery, neuropediatrics, general pathology, and geriatrics. This is the only comprehensive authoritative review of the neuropathology of metabolic and neurodegenerative diseases. In the future, genetic engineering is expected to provide effective molecular therapy for the countless diseases currently termed "metabolic" or "degenerative." Metabolic and Degenerative Diseases of the Central Nervous System is intended to provide a sound morphological platform for these forthcoming events. Key Features * Neuropathology of every disease correlated with an overview of the medical and general pathological changes * Authored by neuropathologists with international reputations as educators and scientists * Highlighted with illustrations from the authors' own archives and contributions from colleagues throughout the world

Neurological Complications of Infectious Diseases

Neurological Complications of Infectious Diseases Book
Author : Rodrigo Hasbun, MD MPH,Karen C. Bloch, MD MPH,Adarsh Bhimraj, MD
Publisher : Humana
Release : 2021-12-28
ISBN : 9783030560867
Language : En, Es, Fr & De

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Book Description :

This book offers a comprehensive review of the most common infectious diseases that affect the nervous system. Written by international experts, it provides a guide to clinicians for accurately diagnosing and treating these challenging syndromes. Organized into six sections, the book presents didactic, up-to-date information on the following topics relating to central nervous system (CNS) infections: diagnosis and evaluation of the patient, bacterial, viral, fungal and mycobacterial infections, disorders of the spinal cord, and a myriad of miscellaneous infections. Chapters specifically reflect and look to resolve the common obstacles clinicians face in the field, such as having unknown etiologies on the majority of CNS infections, insensitive and slow microbiological techniques, an increasing number of immunosuppressed individuals with atypical presentations and pathogens, and a lack of standardized diagnostic algorithms. A complex yet accessible addition to the Current Clinical Neurology Series, Neurological Complications of Infectious Diseases invaluably examines a wide range of infections that have neurological complications and sequelae.

Diseases of the Nervous System

Diseases of the Nervous System Book
Author : Arthur K. Asbury,Guy M. McKhann,W. Ian McDonald,Peter J. Goadsby,Justin C. McArthur
Publisher : Cambridge University Press
Release : 2002-11-11
ISBN : 9780521793513
Language : En, Es, Fr & De

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Book Description :

The third edition of a neurology classic, this two-volume text is the most comprehensive neurology reference available. Written by leading international experts in the field, it encompasses the basic neuroscience and clinical features of the full range of neurological disorders. Disease mechanisms are reviewed comprehensively, with particular relevance to the principles of therapy. Each section, under the direction of one of the distinguished editors, is a text-within-a-text, offering the most reliable account of its topic currently available.