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Disease Pathways

Disease Pathways Book
Author : Anastasia P. Nesterova,Anton Yuryev,Eugene A. Klimov,Maria Zharkova,Maria Shkrob,Natalia V. Ivanikova,Sergey Sozin,Vladimir Sobolev
Publisher : Elsevier
Release : 2019-10-18
ISBN : 0128170875
Language : En, Es, Fr & De

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Book Description :

Disease Pathways: An Atlas of Human Disease Signaling Pathways is designed to fill a void of illustrated reviews about the cellular mechanisms of human diseases. It covers 42 of the most common non-oncologic diseases and illustrates the connections between the molecular causes of the disease and its symptoms. This resource provides readers with detailed information about the disease molecular pathways, while keeping the presentation simple. Pathway models that aggregate the knowledge about protein–protein interactions have become indispensable tools in many areas of molecular biology, pharmacology, and medicine. In addition to disease pathways, the book includes a comprehensive overview of molecular signaling biology and application of pathway models in the analysis of big data for drug discovery and personalized medicine. This is a must-have reference for general biologists, biochemists, students, medical workers, and everyone interested in the cellular and molecular mechanisms of human disease. Over 145 full-color illustrations of the molecular and cellular cascades underlying the disease pathology. Disease pathways are based on computational models from Elsevier’s Disease Pathway Collection, published for the first time outside of Pathway Studio® commercial software. Each relationship on the pathway models is supported by references to scientific articles and can be examined at freely available online resources.

Innate Immunity Pathways in Autoimmune Diseases

Innate Immunity Pathways in Autoimmune Diseases Book
Author : Moncef Zouali,Antonio La Cava
Publisher : Frontiers Media SA
Release : 2019-12-10
ISBN : 2889632369
Language : En, Es, Fr & De

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Book Description :

Download Innate Immunity Pathways in Autoimmune Diseases book written by Moncef Zouali,Antonio La Cava, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Signaling Pathways in Liver Diseases

Signaling Pathways in Liver Diseases Book
Author : Pierre-Alain Clavien
Publisher : Springer Science & Business Media
Release : 2005
ISBN : 9783540229346
Language : En, Es, Fr & De

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Book Description :

Recent advances have carried hepatology to new frontiers. The increasing frequency with which steatotic and cirrhotic livers undergo surgery obliges liver surgeons and hepatologists to understand the molecular mechanisms at play in these situations. Comprehension of the signaling pathways participating in liver regeneration, hepatocellular apoptosis and ischemia/reperfusion injury is essential. This book serves as a source of information to facilitate the reading of the literature and the planning of trials. Translational medicine implies knowledge of the molecular targets of novel therapeutic strategies. It is our goal to stimulate more research that can lead to more exchanges between the laboratory, the clinical ward and the operating room.

Signaling Pathways in Liver Diseases

Signaling Pathways in Liver Diseases Book
Author : Jean-Francois Dufour,Pierre-Alain Clavien
Publisher : Springer Science & Business Media
Release : 2009-12-01
ISBN : 9783642001505
Language : En, Es, Fr & De

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Book Description :

Signaling Pathways in Liver Diseases, 2nd edition focuses on signaling pathways which are particularly important in liver diseases. Recent progress brought hepatology to new frontiers. The increasing frequency of surgery on steatotic and cirrhotic liver obliges liver surgeons and hepatologists to understand the molecular mechanisms at play in these situations and how they can be influenced. Better comprehension of the cellular mechanisms participating in liver regeneration, hepato-cellular apoptosis and ischemia/reperfusion inquiry is mirrored by a dramatic increase in complexity. The number and scope of publications is intimidating and difficult for busy individuals to extract a coherent framework. This book will serve as a source of information facilitating the reading of the literature and the planning of trials. Translational medicine implies knowledge of the molecular targets for novel therapeutic strategies. It will furthermore stimulate more research and lead to better exchange between the laboratory, the clinical ward and the operation room.

Signal Transduction Pathways Mechanisms and Diseases

Signal Transduction  Pathways  Mechanisms and Diseases Book
Author : Ari Sitaramayya
Publisher : Springer Science & Business Media
Release : 2009-12-02
ISBN : 9783642021121
Language : En, Es, Fr & De

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Book Description :

Providing an overview of recent developments in the field of signal transduction, this volume emphasizes direct clinical significance. As such, topics like nuclear receptors, apoptosis, growth factors, cell cycles and cancer are examined.

Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases

Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases Book
Author : Marek Los,Spencer B. Gibson
Publisher : Springer Science & Business Media
Release : 2006-06-20
ISBN : 0387236953
Language : En, Es, Fr & De

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Book Description :

As our understanding of apoptotic pathway expands, we are coming to realize the great potential of utilizing this pathway to treat diseases such as cancer. The book attempts to review, summarize, and speculate on the apoptotic pathways, how are they regulated and how targeted therapies are being used to treat a wide variety of diseases. Special emphasis is placed on cancer since new treatments either being developed or currently in the clinical setting are showing great promise to increase survival rates for cancer patients. Chapters will address the biology behind regulating the apoptotic pathways and what goes wrong in disease states whereas other chapters will concentrate on new therapies targeting apoptotic pathways. The reader by the end of the book should have greater insight into the understanding and utilization of apoptotic pathways to fight diseases such as cancer.

The Person with Alzheimer s Disease

The Person with Alzheimer s Disease Book
Author : Phyllis Braudy Harris
Publisher : JHU Press
Release : 2002-06-06
ISBN : 9780801868771
Language : En, Es, Fr & De

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Book Description :

Few families are untouched by Alzheimer's disease or a related dementia. Moving accounts of what it is like to care for someone with this disease have already been published, as well as how-to books that offer caregivers advice and information on coping. But this book is the first to provide a comprehensive report of what it is like to have dementia oneself—the subjective experience of living with progressive memory loss. Each chapter discusses a different aspect of having dementia, from the initial assessment and diagnosis through placement in a nursing home. The discussions are grounded in qualitative research and case studies, which convey the variable and personal nature of the experience. They seek to help clinicians, researchers, students, and caregivers (both professionals and family members) understand the experience of dementia, and thereby to promote better caregiving through a person-centered approach. Contributors: Kathleen Kahn-Denis, Judson Retirement Community; Casey Durkin, a psychotherapist in Cleveland, Ohio; Jane Gilliard, Dementia Voice, UK; Phyllis Braudy Harris, John Carroll University; John Keady, University of Wales, UK; John Killick, University of Stirling, UK; Rebecca G. Logsdon, University of Washington; Charlie Murphy, University of Stirling, UK; Alison Phinney, University of British Columbia, Canada; Steven R. Sabat, Georgetown University; Dorothy Seman, Alzheimer's Family Care Center, Chicago; Lisa Snyder, University of California, San Diego; Jane Stansell, Alzheimer's Family Care Center, Chicago; Gloria Sterin, Shaker Heights, Ohio; Jon C. Stuckey, Messiah College; Robyn Yale, Consultant to the Alzheimer's Association, San Francisco; Rosalie Young, Wayne State University School of Medicine.

The Jak Stat Pathway in Hematopoiesis and Disease

The Jak Stat Pathway in Hematopoiesis and Disease Book
Author : Alister C. Ward
Publisher : Springer Science & Business Media
Release : 2002-12-31
ISBN : 9780306474248
Language : En, Es, Fr & De

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Book Description :

This book for the first time comprehensively surveys the research investigating the Jak-Stat pathway and its role in normal blood development as well as its perturbation in disease. It draws on the expertise of world-renowned medical researchers to take the reader from basic biology through to recent therapeutic advances.

Parkinson s Disease and Movement Disorders

Parkinson s Disease and Movement Disorders Book
Author : Joseph Jankovic,Eduardo Tolosa
Publisher : Lippincott Williams & Wilkins
Release : 2007
ISBN : 9780781778817
Language : En, Es, Fr & De

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Book Description :

Written by an international group of renowned experts, the Fifth Edition of this premier reference provides comprehensive, current information on the genetics, pathophysiology, diagnosis, medical and surgical treatment, and behavioral and psychologic concomitants of all common and uncommon movement disorders. Coverage includes Parkinson's disease, other neurodegenerative diseases, tremors, dystonia, Tourette's syndrome, Huntington's disease, and ataxias. This edition features extensive updates on genetics, imaging, and therapeutics of Parkinson's disease, other parkinsonian disorders, and all hyperkinetic movement disorders. A bound-in CD-ROM, Video Atlas of Movement Disorders, demonstrates the movement and posture abnormalities and other disturbances associated with Parkinson's disease and other neurologic disorders.

Nonalcoholic Fatty Liver Disease An Issue of Clinics in Liver Disease E Book

Nonalcoholic Fatty Liver Disease  An Issue of Clinics in Liver Disease   E Book Book
Author : Arun J. Sanyal
Publisher : Elsevier Health Sciences
Release : 2012-08-12
ISBN : 145574736X
Language : En, Es, Fr & De

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Book Description :

Dr. Sanyal's expertise as Chairman of the Division of Hepatology at Virginia Commonwealth University and the breadth of his published articles in hepatology make him the perfect person to compile state-of-the-art reviews on the topic of NASH/fatty liver. The articles in this issue address the following topics: The Genetic Epidemiology of Nonalcoholic Fatty Liver Disease; Relevance of Liver Histology to Predict Clinically Meaningful Outcomes in NASH; Mechanisms of Simple Hepatic Steatosis; Cellular and Molecular Basis for Phenotype of Steatohepatitis; Mechanisms of Disease Progression in NASH: New Paradigms; Can NASH Be Diagnosed, Graded and Staged Non-Invasively?; Is NAFLD in Children the Same Disease as in Adults?; The Cardiovascular Link to NAFLD: A Critical Analysis; Impact of Behavioral Disturbances and Their Treatment on Obesity and NAFLD; and Management of NASH.

Molecular Pathology of Lung Diseases

Molecular Pathology of Lung Diseases Book
Author : Dani S. Zander,Helmut Popper,Jaishree Jagirdar,Abida Haque,Roberto Barrios
Publisher : Springer Science & Business Media
Release : 2010-05-26
ISBN : 9780387724300
Language : En, Es, Fr & De

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Book Description :

This major work, complete with 150 illustrations, many of them in color, bridges the gap between clinical pulmonary pathology and basic molecular science. Through a highly visual approach that features an abundance of tables and diagrams, the book offers a practical disease-based overview. The first two sections of the volume provide the reader with general concepts, terminology and procedures in molecular pathology. The remainder of the volume is subdivided into neoplastic and non-neoplastic lung diseases with detailed chapters covering the current molecular pathology of specific diseases. The book will be essential reading for pathologists, pulmonologists, thoracic surgeons and other health care providers interested in lung disease.

Atherothrombosis and Coronary Artery Disease

Atherothrombosis and Coronary Artery Disease Book
Author : Valentin Fuster,Eric J. Topol,Elizabeth G. Nabel
Publisher : Lippincott Williams & Wilkins
Release : 2005
ISBN : 9780781735834
Language : En, Es, Fr & De

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Book Description :

Written by the world’s foremost authorities, this volume provides comprehensive coverage of current approaches to the prevention, diagnosis, and management of atherothrombosis and its coronary and noncoronary complications. This edition has been thoroughly updated, sharply focused on clinical information, and trimmed to one manageable volume. Coverage begins with a review of risk factors and prevention, emphasizing lipid abnormalities, hypertension, smoking, diabetes, and obesity. Subsequent sections examine the pathogenesis of atherosclerosis, markers and imaging, acute coronary syndromes, chronic stable angina, and noncoronary atherothrombosis. Clinical presentations, medical management, and the latest interventional strategies are included.

Biotechnology Annual Review

Biotechnology Annual Review Book
Author : M. Raafat El-Gewely
Publisher : Elsevier
Release : 2005-09-12
ISBN : 9780444519528
Language : En, Es, Fr & De

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Book Description :

Biotechnology is a diverse, complex and rapidly evolving field. Students and experienced researchers alike face the challenges of staying on top of developments in their field of specialty and maintaining a broader overview of the field as a whole. Volumes containing competent reviews on a diverse range of topics in the field fulfill the dual role of broadening and updating biotechnologists' knowledge. The current volume is an excellent example of such a book. The topics covered range from classical issues in biotechnology - such as, vehicles for the production of biotechnology products and methods for their detection, separation and analysis - to topics that are focused on the role of biotechnology in the health sciences. The information presented in this book will therefore will be of great value to both experienced biotechnologists and biotechnologists in training.

Research in Computational Molecular Biology

Research in Computational Molecular Biology Book
Author : Bonnie Berger
Publisher : Springer Science & Business Media
Release : 2010-04-20
ISBN : 3642126820
Language : En, Es, Fr & De

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Book Description :

This volume contains the papers presented at RECOMB 2010: the 14th Annual International Conference on Research in Computational Molecular Biology held in Lisbon, Portugal, during April 25–28, 2010. The RECOMB conference series was started in 1997 by Sorin Istrail, Pavel Pevzner, and Michael Waterman. RECOMB 2010 was hosted by INESC-ID and Instituto Superior Tecnico, or- nized by a committee chaired by Arlindo Oliveira and took place at the Int- national Fair of Lisbon Meeting Centre. This year, 36 papers were accepted for presentation out of 176 submissions. The papers presented were selected by the Program Committee (PC) assisted by a number of external reviewers. Each paper was reviewed by three members of the PC, or by external reviewers, and there was an extensive Web-based discussion over a period of two weeks, leading to the ?nal decisions. RECOMB 2010 also introduced a Highlights Track, in which six additional presentations by senior authors were chosen from papers published in 2009. The RECOMB conferenceseriesiscloselyassociatedwiththeJournalofComputational Biology, which traditionally publishes special issues devoted to presenting full versions of selected conference papers.

Clinical Pathways In Vitreoretinal Disease

Clinical Pathways In Vitreoretinal Disease Book
Author : Scott M. Steidl,Mary Elizabeth Hartnett
Publisher : Thieme
Release : 2011-01-01
ISBN : 1604064587
Language : En, Es, Fr & De

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Book Description :

Vitreoretinal disease is the leading cause of severe vision loss in most developed countries. This all-encompassing new book is designed to enhance diagnosis and treatment of retinal pathology as you proceed from initial finding to differential diagnosis and treatment. Using evidence-based medicine to develop management strategies and featuring pathway diagrams and decision-making trees, the book links specific symptoms to the appropriate diagnosis and most effective treatment. A top team of retinal specialists have come together to create this pace-setting reference, covering everything from retinal detachment and hemorrhage, to pigmented lesions and noninfectious inflammation. Chapters are uniquely arranged by presenting symptom instead of diagnosis, allowing you to find material quickly and easily. Key features of this valuable book:Broad coverage of all important topics, including both pediatric and adult retinal diseasesClinical decision-making trees and pathway diagrams offering a yes-or-no approach to diagnosis and treatmentBeneficial question and answer format provides clarity and explanations for specific problemsHelpful table of contents organized by presenting symptomCLINICAL PATHWAY IN VITREORETINAL DISEASE is essential for all retina specialists, general ophthalmologists, and residents who treat severe vision loss. It offers the valuable information needed to reach an accurate diagnosis and provide optimal patient care. The book also serves as an excellent text for retina and general ophthalmology courses.

Pathways for Sustainable Sanitation

Pathways for Sustainable Sanitation Book
Author : Anonim
Publisher : IWA Publishing
Release : 2008-01-01
ISBN : 1843391961
Language : En, Es, Fr & De

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Book Description :

The report is a product arising from the work of t

Neurological Disease New Insights for the Healthcare Professional 2012 Edition

Neurological Disease  New Insights for the Healthcare Professional  2012 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-12-10
ISBN : 1464978352
Language : En, Es, Fr & De

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Book Description :

Neurological Disease: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Neurological Disease in a compact format. The editors have built Neurological Disease: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Neurological Disease in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Neurological Disease: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Animal Models of Human Disease

Animal Models of Human Disease Book
Author : Anonim
Publisher : Academic Press
Release : 2011-03-04
ISBN : 0123848792
Language : En, Es, Fr & De

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Book Description :

Animal experiments have contributed much to our understanding of mechanisms of disease and are important for determining new therapies. This volume reviews the latest research and developments in this field. * Discusses new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields

Sleisenger and Fordtran s Gastrointestinal and Liver Disease E Book

Sleisenger and Fordtran s Gastrointestinal and Liver Disease E Book Book
Author : Mark Feldman,Lawrence S. Friedman,Lawrence J. Brandt
Publisher : Elsevier Health Sciences
Release : 2010-05-03
ISBN : 1437727670
Language : En, Es, Fr & De

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Book Description :

Make optimal use of the newest techniques, technologies, and treatments with Sleisenger and Fordtran's Gastrointestinal and Liver Disease - the indispensable information source in this broad field! Edited by Mark Feldman, MD, Lawrence S. Friedman, MD, and Lawrence J. Brandt, MD, this 9th Edition equips you with the amassed knowledge of hundreds of respected authorities from around the world, helping you to overcome all of your most complex clinical challenges and make the most effective use of the newest techniques, technologies, and treatments. Significant updates on bariatric surgery, Barrett's esophagus, and many other evolving areas keep your practice current. Full-text online access includes downloadable illustrations and links to reference abstracts. The result remains the indispensable core reference in gastroenterology and hepatology. World-renowned experts provide reliable guidance on every area of your field. A consistent, full-color chapter design lets you find information quickly. Significant updates on bariatric surgery, Barrett's esophagus, endoscopic ultrasound, endosonography, treatment of liver disease, and much more keep you current on the latest advances. Many new contributors from all over the world provide you with fresh insights on all areas of gastroenterology and hepatology. Full-text online access via Expert Consult includes downloadable illustrations and links to reference abstracts.

The Hereditary Basis of Rheumatic Diseases

The Hereditary Basis of Rheumatic Diseases Book
Author : Rikard Holmdahl
Publisher : Springer Science & Business Media
Release : 2006-07-02
ISBN : 3764374195
Language : En, Es, Fr & De

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Book Description :

Rheumatoid Arthritis (RA) represents a complex disease where the inheritable component has been estimated to be up to 60%. This PIR volume deals with the genetic basis and regulation of rheumatic diseases. The first part of the book describes genetic studies on rheumatic diseases. The second part deals with the shared heredity of rheumatic diseases, e.g., RA, lupus and ankylosing spondylitis. The third part of the volume describes tools for analysing genetic complexity, ranging from animal models to new molecular tools. The volume is essential reading for researchers and clinicians from rheumatology, inflammation research, immunology, and cell and molecular biology.