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Disease Pathways

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Disease Pathways

Disease Pathways Book
Author : Anastasia P. Nesterova,Anton Yuryev,Eugene A. Klimov,Maria Zharkova,Maria Shkrob,Natalia V. Ivanikova,Sergey Sozin,Vladimir Sobolev
Publisher : Elsevier
Release : 2019-10-18
ISBN : 0128170875
Language : En, Es, Fr & De

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Book Description :

Disease Pathways: An Atlas of Human Disease Signaling Pathways is designed to fill a void of illustrated reviews about the cellular mechanisms of human diseases. It covers 42 of the most common non-oncologic diseases and illustrates the connections between the molecular causes of the disease and its symptoms. This resource provides readers with detailed information about the disease molecular pathways, while keeping the presentation simple. Pathway models that aggregate the knowledge about protein–protein interactions have become indispensable tools in many areas of molecular biology, pharmacology, and medicine. In addition to disease pathways, the book includes a comprehensive overview of molecular signaling biology and application of pathway models in the analysis of big data for drug discovery and personalized medicine. This is a must-have reference for general biologists, biochemists, students, medical workers, and everyone interested in the cellular and molecular mechanisms of human disease. Over 145 full-color illustrations of the molecular and cellular cascades underlying the disease pathology. Disease pathways are based on computational models from Elsevier’s Disease Pathway Collection, published for the first time outside of Pathway Studio® commercial software. Each relationship on the pathway models is supported by references to scientific articles and can be examined at freely available online resources.

Signaling Pathways in Liver Diseases

Signaling Pathways in Liver Diseases Book
Author : Jean-Francois Dufour,Pierre-Alain Clavien
Publisher : John Wiley & Sons
Release : 2015-08-24
ISBN : 1118663365
Language : En, Es, Fr & De

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Book Description :

Signaling Pathways in Liver Diseases, Third Edition again provides hepatologists and hepatology researchers with an expert overview of the complex and novel cellular/extracellular signaling pathways in the liver, and their role in liver diseases. The last few years have seen a great number of developments in this field, which in turn have led to new opportunities for innovative treatments; however, the intricacy of these pathways and their interactions continue to provide a real challenge for clinicians. This outstanding book compiles the emerging knowledge into a single expert resource, cataloguing and organizing it into an accessible and understandable format. With increased focus on the comprehension of cellular mechanisms involved in steatohepatitis, cirrhosis, and liver tumors, which has led to changes in the management of these diseases, this new edition also sees the introduction of exciting new chapters on key emerging areas such as: Autophagy Notch Pathway P13K/PTEN Signaling in Liver Diseases Sirtuins Hepcidin and Iron Epigenetic Regulation of Hepatic Stellate Cells and Liver Fibrosis Oxidative Stress and Signaling in the Liver. Professors Dufour and Clavien have assembled an all-star cast of chapter authors, each of whom has provided clear and appropriate illustrations to reinforce the text, with a key points box offering a concise and handy summary. Self-assessment questions and answers allow the reader to test their own knowledge. Signaling Pathways in Liver Disease, Third Edition is the perfect educational and reference tool to bridge the information exchange between the laboratory, the clinical ward, and the operating room, and an essential tool for the modern-day hepatologist.

The Person with Alzheimer s Disease

The Person with Alzheimer s Disease Book
Author : Phyllis Braudy Harris
Publisher : JHU Press
Release : 2002-06-06
ISBN : 9780801868771
Language : En, Es, Fr & De

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Book Description :

Few families are untouched by Alzheimer's disease or a related dementia. Moving accounts of what it is like to care for someone with this disease have already been published, as well as how-to books that offer caregivers advice and information on coping. But this book is the first to provide a comprehensive report of what it is like to have dementia oneself—the subjective experience of living with progressive memory loss. Each chapter discusses a different aspect of having dementia, from the initial assessment and diagnosis through placement in a nursing home. The discussions are grounded in qualitative research and case studies, which convey the variable and personal nature of the experience. They seek to help clinicians, researchers, students, and caregivers (both professionals and family members) understand the experience of dementia, and thereby to promote better caregiving through a person-centered approach. Contributors: Kathleen Kahn-Denis, Judson Retirement Community; Casey Durkin, a psychotherapist in Cleveland, Ohio; Jane Gilliard, Dementia Voice, UK; Phyllis Braudy Harris, John Carroll University; John Keady, University of Wales, UK; John Killick, University of Stirling, UK; Rebecca G. Logsdon, University of Washington; Charlie Murphy, University of Stirling, UK; Alison Phinney, University of British Columbia, Canada; Steven R. Sabat, Georgetown University; Dorothy Seman, Alzheimer's Family Care Center, Chicago; Lisa Snyder, University of California, San Diego; Jane Stansell, Alzheimer's Family Care Center, Chicago; Gloria Sterin, Shaker Heights, Ohio; Jon C. Stuckey, Messiah College; Robyn Yale, Consultant to the Alzheimer's Association, San Francisco; Rosalie Young, Wayne State University School of Medicine.

Identification of Novel Pathways for Cardiac Development and Disease Via Conditional Genetic Manipulation of Cardioblasts and Cardiomyocyte Lineages

Identification of Novel Pathways for Cardiac Development and Disease Via Conditional Genetic Manipulation of Cardioblasts and Cardiomyocyte Lineages Book
Author : Jason Tat-Kwong Lam
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Identification of Novel Pathways for Cardiac Development and Disease Via Conditional Genetic Manipulation of Cardioblasts and Cardiomyocyte Lineages book written by Jason Tat-Kwong Lam, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases

Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases Book
Author : Marek Los,Spencer B. Gibson
Publisher : Springer Science & Business Media
Release : 2006-06-20
ISBN : 0387236953
Language : En, Es, Fr & De

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Book Description :

As our understanding of apoptotic pathway expands, we are coming to realize the great potential of utilizing this pathway to treat diseases such as cancer. The book attempts to review, summarize, and speculate on the apoptotic pathways, how are they regulated and how targeted therapies are being used to treat a wide variety of diseases. Special emphasis is placed on cancer since new treatments either being developed or currently in the clinical setting are showing great promise to increase survival rates for cancer patients. Chapters will address the biology behind regulating the apoptotic pathways and what goes wrong in disease states whereas other chapters will concentrate on new therapies targeting apoptotic pathways. The reader by the end of the book should have greater insight into the understanding and utilization of apoptotic pathways to fight diseases such as cancer.

Signaling Pathways in Liver Diseases

Signaling Pathways in Liver Diseases Book
Author : Pierre-Alain Clavien
Publisher : Springer Science & Business Media
Release : 2005
ISBN : 9783540229346
Language : En, Es, Fr & De

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Book Description :

Recent advances have carried hepatology to new frontiers. The increasing frequency with which steatotic and cirrhotic livers undergo surgery obliges liver surgeons and hepatologists to understand the molecular mechanisms at play in these situations. Comprehension of the signaling pathways participating in liver regeneration, hepatocellular apoptosis and ischemia/reperfusion injury is essential. This book serves as a source of information to facilitate the reading of the literature and the planning of trials. Translational medicine implies knowledge of the molecular targets of novel therapeutic strategies. It is our goal to stimulate more research that can lead to more exchanges between the laboratory, the clinical ward and the operating room.

Medical Biochemistry

Medical Biochemistry Book
Author : Miriam D. Rosenthal,Robert H. Glew
Publisher : John Wiley & Sons
Release : 2011-09-20
ISBN : 1118210298
Language : En, Es, Fr & De

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Book Description :

Metabolism includes various pathways of chemical reactions; understanding these pathways leads to an improved knowledge of the causes, preventions, and cures for human diseases. Medical Biochemistry: Human Metabolism in Health and Disease provides a concise yet thorough explanation of human metabolism and its role in health and diseases. Focusing on the physiological context of human metabolism without extensive consideration of the mechanistic principles of underlying enzymology, the books serves as both a primary text and resource for students and professional in medical, dental, and allied health programs.

Sirtuin Biology in Cancer and Metabolic Disease

Sirtuin Biology in Cancer and Metabolic Disease Book
Author : Kenneth Maiese
Publisher : Elsevier
Release : 2021-02-20
ISBN : 0128224843
Language : En, Es, Fr & De

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Book Description :

Sirtuin Biology in Cancer and Metabolic Disease: Cellular Pathways for Clinical Discovery offers a compelling and thought-provoking perspective for the examination of the intriguing biology of sirtuins that ties cancer and metabolic disease together and provides a critical platform for the development of sirtuin-based novel therapeutic strategies to effectively treat cancer and metabolic disorders with precision in order to minimize any potentially detrimental clinical outcomes. An exciting prospect for the development of innovative therapeutics for cancer and metabolic disorders involves sirtuins. Sirtuins are histone deacetylases that have an intricate role in the onset and development of cancer and metabolic disease. Implementing a translational medicine format, this innovative reference highlights the ability of sirtuins to oversee critical pathways that involve stem cell maintenance, cellular proliferation, metabolic homeostasis, apoptosis, and autophagy that can impact cellular dysfunction and unchecked cellular growth that can occur during cancer and metabolic disease. Each chapter offers an intuitive perspective of advances on the application of sirtuin pathways for cancer and metabolic disease that will be become a "go-to" resource for a broad audience of scientists, physicians, pharmaceutical industry experts, nutritionists, and students. Chapters are authored by internationally recognized experts who elucidate the intimate relationship between cancer and metabolic disease that intersects with sirtuin pathways Presents the basic and clinical role of sirtuins in regard to cancer and metabolic disease Summarizes the multidiscipline views and publications for this exciting field of sirtuins for the development of new clinical treatments for cancer and metabolic disease Provides a vital foundation for a broad audience of healthcare providers, scientists, drug developers, and students in both clinical and research settings

Heat Shock Proteins in Signaling Pathways

Heat Shock Proteins in Signaling Pathways Book
Author : Alexzander A. A. Asea,Punit Kaur
Publisher : Springer
Release : 2019-07-09
ISBN : 3030039528
Language : En, Es, Fr & De

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Book Description :

Signaling pathways is a comprehensive mechanism by which all cellular organisms communicate internally and externally with their microenvironment. This is a highly complex and exact process. Errors in signaling pathways and in the processing of cellular information are known to be responsible for the majority of diseases including cancer, inflammatory and neurological disorders. Knowledge gained from the better understanding of signaling pathways will help in elucidating disease processes and will assist in development and design of novel targeted treatment therapies to combat human diseases and disorders. Heat shock proteins (HSP) are uniquely involved in a number of critical signaling pathways. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed chapters that review present research activity and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Translational Medicine, Clinical Research, Human Physiology, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.

Pathways to Scientific Teaching

Pathways to Scientific Teaching Book
Author : Diane Ebert-May,Janet Hodder
Publisher : Sinauer Associates, Incorporated
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This book is based on a series of Pathways articles that illustrate effective instructional methods to help students gain conceptual understanding in ecology. It presents a philosophy of scientific teaching based on pedagogical principles designed to improve learning.

Energy Balance and Colorectal Cancer

Energy Balance and Colorectal Cancer Book
Author : Universiteit Maastricht
Publisher : Unknown
Release : 2013
ISBN : 9789082130805
Language : En, Es, Fr & De

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Book Description :

Download Energy Balance and Colorectal Cancer book written by Universiteit Maastricht, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Clinical Pathways In Vitreoretinal Disease

Clinical Pathways In Vitreoretinal Disease Book
Author : Scott M. Steidl,Mary Elizabeth Hartnett
Publisher : Thieme
Release : 2011-01-01
ISBN : 1604064587
Language : En, Es, Fr & De

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Book Description :

Vitreoretinal disease is the leading cause of severe vision loss in most developed countries. This all-encompassing new book is designed to enhance diagnosis and treatment of retinal pathology as you proceed from initial finding to differential diagnosis and treatment. Using evidence-based medicine to develop management strategies and featuring pathway diagrams and decision-making trees, the book links specific symptoms to the appropriate diagnosis and most effective treatment. A top team of retinal specialists have come together to create this pace-setting reference, covering everything from retinal detachment and hemorrhage, to pigmented lesions and noninfectious inflammation. Chapters are uniquely arranged by presenting symptom instead of diagnosis, allowing you to find material quickly and easily. Key features of this valuable book:Broad coverage of all important topics, including both pediatric and adult retinal diseasesClinical decision-making trees and pathway diagrams offering a yes-or-no approach to diagnosis and treatmentBeneficial question and answer format provides clarity and explanations for specific problemsHelpful table of contents organized by presenting symptomCLINICAL PATHWAY IN VITREORETINAL DISEASE is essential for all retina specialists, general ophthalmologists, and residents who treat severe vision loss. It offers the valuable information needed to reach an accurate diagnosis and provide optimal patient care. The book also serves as an excellent text for retina and general ophthalmology courses.

Chronic Disease Management

Chronic Disease Management Book
Author : Aspen Reference Group (Aspen Publishers)
Publisher : Delmar Pub
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Chronic Disease Management: Clinical Pathways and Guidelines is a companion volume to another Aspen manual, Chronic Disease Patient Education Manual. This manual provides clinicians with clinical pathways and guidelines that span the continuum of care for the five chronic disease states. In addition, it addresses the essentials of administering a disease management program, with information on developing and implementing clinical guidelines/pathways; measuring and managing outcomes; and monitoring and improving patient satisfaction. Chronic Disease Management with its pathways and guidelines covering the entire health care continuum is an ideal resource for providers and payers struggling to render seamless, cost-effective, and outcome-oriented care.

Telcr Gde Nutr Pathways

Telcr Gde Nutr Pathways Book
Author : Sizer
Publisher : Unknown
Release : 2002-08
ISBN : 9780534578015
Language : En, Es, Fr & De

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Book Description :

The Telecourse Guide ties together information from the text, diet Analysis Plus Software and the Nutrition Pathways Telecourse Video Course provided by the LeCroy Center for Educational Telecommunications.

Critical Pathways in Therapeutic Intervention

Critical Pathways in Therapeutic Intervention Book
Author : David C. Saidoff,Andrew L. McDonough
Publisher : Mosby Incorporated
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Rehabilitation methods to be considered before surgical intervention are discussed in this book. Ideas and concepts from sports medicine, physiotherapy, occupational therapy, geriatrics, ergonomics, kinesiology and physiatry are used in a case-study format covering many common injuries.

Pathways of Human Development

Pathways of Human Development Book
Author : Mohammad Shafii,Sharon Lee Shafii
Publisher : Unknown
Release : 1982
ISBN : 9780865770492
Language : En, Es, Fr & De

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Book Description :

Download Pathways of Human Development book written by Mohammad Shafii,Sharon Lee Shafii, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Conserved Systemic Lupus Erythematosus Pathways in Murine Models

Conserved Systemic Lupus Erythematosus Pathways in Murine Models Book
Author : Jiabin Liu (Ph.D.)
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Conserved Systemic Lupus Erythematosus Pathways in Murine Models book written by Jiabin Liu (Ph.D.), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Drugs for Heart Disease

Drugs for Heart Disease Book
Author : John Hamer
Publisher : Unknown
Release : 1979
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Drugs for Heart Disease book written by John Hamer, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.