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Discovery And Development Of Anti Breast Cancer Agents From Natural Products

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Discovery and Development of Anti inflammatory Agents from Natural Products

Discovery and Development of Anti inflammatory Agents from Natural Products Book
Author : Goutam Brahmachari
Publisher : Elsevier
Release : 2019-07-11
ISBN : 0128169931
Language : En, Es, Fr & De

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Book Description :

Discovery and Development of Anti-inflammatory Agents from Natural Products, the latest volume in the Natural Product Drug Discovery series, presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations, with this volume focusing on molecules of natural origin and their synthetic analogues that have the potential to act against the pathogens responsible for inflammatory diseases. All aspects of each are covered, including isolations and structure elucidations, in vitro and in vivo biological activity, synthetic optimization, investigations of pharmacodynamics and kinetics, and the structure-activity relationships of anti-inflammatory natural products. Written by active researchers and leading experts, this book brings together an overview of current discoveries and trends in this field. It will be a valuable resource for researchers working to discover promising leads for the development of pharmaceuticals in the prevention and treatment of anti-inflammatory diseases. Features contributions from active researchers and leading experts working in medicinal natural products and herbal formulations Includes recent, cutting-edge advances on medicinal natural products, along with preventative therapies for different kinds of inflammation-directed diseases Offers an authoritative source of information on the industrial application of natural products for medicinal purposes

The Story of Taxol

The Story of Taxol Book
Author : Jordan Goodman,Vivien Walsh,Professor in Innovation Management Manchester Business School Vivien Walsh
Publisher : Cambridge University Press
Release : 2001-03-05
ISBN : 9780521561235
Language : En, Es, Fr & De

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Book Description :

The story of taxol; arguably the most celebrated and controversial natural product in recent years.

Discovery and Development of Neuroprotective Agents from Natural Products

Discovery and Development of Neuroprotective Agents from Natural Products Book
Author : Goutam Brahmachari
Publisher : Elsevier
Release : 2017-05-18
ISBN : 0128097698
Language : En, Es, Fr & De

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Book Description :

Discovery and Development of Neuroprotective Agents from Natural Products draws together global research on medicinal agents from natural sources as starting points for the design of neuroprotective drugs. From the prediction of promising leads and identification of active agents to the extraction of complex molecules, the book explores a range of important topics to support the development of safer, more economical therapeutics for these increasingly prevalent diseases. Beginning with an overview of current developments in the field, the book goes on to explore the identification, extraction and phytochemistry of such neuroprotective agents as antioxidants, biophenols and naturally occurring anti-inflammatory steroid analogues. Specific natural sources of bioactive agents are reviewed, and the development of these agents into therapeutics for a number of specific neurological disorders, including Alzheimer’s disease, Parkinson’s disease and ischemic brain stroke, are discussed. Combining the expertise of specialists from around the world, this in the Natural Products Drug Discovery series aims to support and encourage researchers in the investigation of natural sources as starting points for the development of standardized, safe and effective neuroprotective drugs. Features chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery Includes comprehensive coverage of cutting-edge research advances in the design of drugs from natural products targeted at different kinds of neurodegenerative diseases Offers a practical review of identification, isolation and extraction techniques to support medicinal chemists in the lab

New Approaches to Natural Anticancer Drugs

New Approaches to Natural Anticancer Drugs Book
Author : Soodabeh Saeidnia
Publisher : Springer
Release : 2015-02-05
ISBN : 3319140272
Language : En, Es, Fr & De

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Book Description :

This book provides an up-to-date review of recently identified natural anti-tumor compounds from various natural origins including plants, fungi, endophytic fungi and marine organisms. It also includes discussion of new areas such as biotechnology and nanoparticles. Chapters explain the challenges and developments in anti-cancer drug discovery approaches, traditional remedies for prevention and treatment of cancer, marine-derived anti-cancer compounds, and antibiotics used as anti-cancer agents, as well as different classes of terpenoids and carbohydrates, which have been the subject of discussion in this field as efficient anti-cancer candidates. This book will be a concise guide for researchers in the field of pharmaceutical sciences, students and residents in pharmacy and medicine as well as those researching phytochemistry and natural products.

Foye s Principles of Medicinal Chemistry

Foye s Principles of Medicinal Chemistry Book
Author : Thomas L. Lemke,David A. Williams
Publisher : Lippincott Williams & Wilkins
Release : 2012-01-24
ISBN : 1609133455
Language : En, Es, Fr & De

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Book Description :

Acclaimed by students and instructors alike, Foye's Principles of Medicinal Chemistry is now in its Seventh Edition, featuring updated chapters plus new material that meets the needs of today's medicinal chemistry courses. This latest edition offers an unparalleled presentation of drug discovery and pharmacodynamic agents, integrating principles of medicinal chemistry with pharmacology, pharmacokinetics, and clinical pharmacy. All the chapters have been written by an international team of respected researchers and academicians. Careful editing ensures thoroughness, a consistent style and format, and easy navigation throughout the text.

Biomedical Index to PHS supported Research

Biomedical Index to PHS supported Research Book
Author : Anonim
Publisher : Unknown
Release : 1992
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Biomedical Index to PHS supported Research book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biomedical Index to PHS supported Research pt A Subject access A H

Biomedical Index to PHS supported Research  pt  A  Subject access A H Book
Author : Anonim
Publisher : Unknown
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Biomedical Index to PHS supported Research pt A Subject access A H book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Bioactive Natural Products for the Management of Cancer from Bench to Bedside

Bioactive Natural Products for the Management of Cancer  from Bench to Bedside Book
Author : Anil K. Sharma
Publisher : Springer
Release : 2019-07-17
ISBN : 9811376077
Language : En, Es, Fr & De

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Book Description :

This book illustrates the importance of the Natural Biometabolites, which offer a rich reservoir of candidate compounds for drug discovery in the battle against cancer. Recent research and development efforts concerning anti-cancer drugs derived from natural products have led to the identification of numerous candidate molecules that inhibit cancer cell proliferation and metastasis using a variety of mechanisms. Given its scope, the book offers a valuable resource for cancer biologists and general oncologists alike, while also benefitting research professionals in Science, Nursing, Medicine, Biochemistry, Genetics and Bioscience who wish to understand the fundamentals of prognosis and prediction in tumorigenesis. Moreover, the book provides an essential platform for understanding drug resistance mechanisms and combatting the growing menace of multidrug resistance.

The Epothilones An Outstanding Family of Anti Tumor Agents

The Epothilones  An Outstanding Family of Anti Tumor Agents Book
Author : Johann H. Mulzer
Publisher : Springer Science & Business Media
Release : 2009-09-29
ISBN : 3211782079
Language : En, Es, Fr & De

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Book Description :

Epothilones have received unusual attention over the past ten years. They are novel antitumor drugs which very much like their predecessor paclitaxel (Taxol) act via microtubule stabilization. In comparison to paclitaxel and a number of alternative drugs with a similar mode of bioaction (e.g. laulimalide, eleutherobin, peluroside, discodermolide) the epothilones have significant advantages, above all very high activity in the nanomolar range and low susceptibility towards multidrug resistance. Epothilone B and several derivatives thereof are in phase I-III clinical trials; one of them (ixabepilone, BMS) is already on the market, others are supposed to appear on the market in the near future. All naturally occurring epothilones have been isolated from Sorangium cellulosum; their antitumor action is traced back to the stabilization of microtubules. In consequence, the formation of the mitototic spindle is prohibited and the cell undergoes apoptosis.

Breast Cancer

Breast Cancer Book
Author : Mary Tagliaferri,Isaac Cohen (O.M.D.),Debu Tripathy
Publisher : Beyond Words/Atria Books
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Some of the world's leading experts on complementary and alternative medicine explain how to incorporate these popular therapeutic options into traditional medicine to provide the best possible treatment for breast cancer, discussing such topics as the benefits of soy foods, nutritional supplements, the positive impact of spiritual practices, and more. 50,000 first printing.

Handbook of Anticancer Drugs from Marine Origin

Handbook of Anticancer Drugs from Marine Origin Book
Author : Se-Kwon Kim
Publisher : Springer
Release : 2014-11-27
ISBN : 3319071459
Language : En, Es, Fr & De

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Book Description :

This timely desk reference focuses on marine-derived bioactive substances which have biological, medical and industrial applications. The medicinal value of these marine natural products are assessed and discussed. Their function as a new and important resource in novel, anticancer drug discovery research is also presented in international contributions from several research groups. For example, the potential role of Spongistatin, Apratoxin A, Eribulin mesylate, phlorotannins, fucoidan, as anticancer agents is explained. The mechanism of action of bioactive compounds present in marine algae, bacteria, fungus, sponges, seaweeds and other marine animals and plants are illustrated via several mechanisms. In addition, this handbook lists various compounds that are active candidates in chemoprevention and their target actions. The handbook also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.

Bioactive Natural Products

Bioactive Natural Products Book
Author : Goutam Brahmachari
Publisher : John Wiley & Sons
Release : 2015-01-20
ISBN : 3527684425
Language : En, Es, Fr & De

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Book Description :

Natural compounds, which have evolved their function over millions of years, are often more efficient than man-made compounds if a specific biological activity is needed, e.g. as an enzyme inhibitor or as a toxin to kill a cancer cell. This book comprising of sixteen technical chapters, highlights the chemical and biological aspects of potential natural products with an intention of unravelling their pharmaceutical applicability in modern drug discovery processes. Key features: Covers the synthesis, semi-synthesis and also biosynthesis of potentially bioactive natural products Features chemical and biological advances in naturally occurring organic compounds describing their chemical transformations, mode of actions, and structure-activity relationships 40 expert scientists from around the world report their latest findings and outline future opportunities for the development of novel and highly potent drugs based on natural products operating at the interface of chemistry and biology Forward-looking: Addresses opportunities and cutting-edge developments rather than well-documented basic knowledge, pinpoints current trends and future directions in this rapidly-evolving field Application-oriented: Throughout the book, the focus is on actual and potential applications in pharmacology and biotechnology This book is an essential resource for natural products chemists, medicinal chemists, biotechnologists, biochemists, pharmacologists, as well as the pharmaceutical and biotechnological industries.

Annual Report

Annual Report Book
Author : Ohio State University. Comprehensive Cancer Center. Arthur G. James Cancer Hospital and Richard J. Solove Research Institute
Publisher : Unknown
Release : 1995
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Annual Report book written by Ohio State University. Comprehensive Cancer Center. Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Chemistry Biological and Pharmacological Properties of African Medicinal Plants

Chemistry  Biological  and Pharmacological Properties of African Medicinal Plants Book
Author : International Organization for Chemical Sciences in Development. Working Group on Plant Chemistry
Publisher : Unknown
Release : 1996
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Chemistry Biological and Pharmacological Properties of African Medicinal Plants book written by International Organization for Chemical Sciences in Development. Working Group on Plant Chemistry, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Human Medicinal Agents from Plants

Human Medicinal Agents from Plants Book
Author : A. Douglas Kinghorn,Manuel F. Balandrin,American Chemical Society. Meeting
Publisher : Amer Chemical Society
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Covers the discovery, development, use and potential use, and regulation of plant-derived drugs. Describes ongoing research for prospective natural drugs with anticancer and anti-infective activities. Features some highly promising compounds, including artemisinin, camptothecin, forskolin, and taxol. Includes coverage of biologically active constituents of terrestrial and marine plants. Also addresses the effects of the destruction of rain forests on drug discovery.

Government Research Directory

Government Research Directory Book
Author : Anonim
Publisher : Gale Cengage
Release : 2010
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Government Research Directory book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2006

Departments of Labor  Health and Human Services  Education  and Related Agencies Appropriations for 2006 Book
Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2006 book written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Anticancer Research

Anticancer Research Book
Author : Anonim
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Anticancer Research book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Wiley Encyclopedia of Chemical Biology Volume 3

Wiley Encyclopedia of Chemical Biology  Volume 3 Book
Author : Tadhg P. Begley
Publisher : Wiley
Release : 2009-02-03
ISBN : 9780470470190
Language : En, Es, Fr & De

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Book Description :

The first major reference at the interface of chemistry, biology, and medicine Chemical biology is a rapidly developing field that uses the principles, tools, and language of chemistry to answer important questions in the life sciences. It has enabled researchers to gather critical information about the molecular biology of the cell and is the fundamental science of drug discovery, playing a key role in the development of novel agents for the prevention, diagnosis, and treatment of disease. Now students and researchers across the range of disciplines that use chemical biology techniques have a single resource that encapsulates what is known in the field. It is an excellent place to begin any chemical biology investigation. Major topics addressed in the encyclopedia include: Applications of chemical biology Biomolecules within the cell Chemical views of biology Chemistry of biological processes and systems Synthetic molecules as tools for chemical biology Technologies and techniques in chemical biology Some 300 articles range from pure basic research to areas that have immediate applications in fields such as drug discovery, sensor technology, and catalysis. Novices in the field can turn to articles that introduce them to the basics, whereas experienced researchers have access to articles exploring the cutting edge of the science. Each article ends with a list of references to facilitate further investigation. With contributions from leading researchers and pioneers in the field, the Wiley Encyclopedia of Chemical Biology builds on Wiley's unparalleled reputation for helping students and researchers understand the crucial role of chemistry and chemical techniques in the life sciences.

Phytochemical Diversity

Phytochemical Diversity Book
Author : E. Chrystal
Publisher : Unknown
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

While the study of the chemicals produced by plants is arguably one of the oldest of the natural product sciences, current global concerns regarding the disappearance of biodiversity, along with the availability of methodology for systematic genetic manipulation and plant tissue culture, have rekindled industrial interest in phytochemical screening. Phytochemical Diversity gives a comprehensive overview of recent discoveries and developments of new products from plants that have potential utility in the pharmaceutical, agrochemical and cosmetic industries. It covers such areas as high throughput screening approaches for the discovery of novel phytochemicals, ethnobotanical drug discovery, comparisons of the chemical diversity available from plants and other natural sources, and adding value to phytochemicals through microbial biotransformations and synthetic approaches. It is particularly timely in its look at the ramifications of the recent UN Convention on Biological Diversity and its impact on the search for new industrial products from plants. This book provides a single source on developments in phytochemical research, with contributions from both academia to industry, and developing to developed countries, which will prove invaluable to bio-organic chemists, biotechnologists and those involved in medicinal and pharmaceutical chemistry.