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Diagnostic Problems In Breast Pathology

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Diagnostic Problems in Breast Pathology

Diagnostic Problems in Breast Pathology Book
Author : Frederick C. Koerner
Publisher : Elsevier Health Sciences
Release : 2009
ISBN : 1416026126
Language : En, Es, Fr & De

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Book Description :

Introduction to the diagnosis of diseases of the breast Concepts basic to the analysis of epithelial proliferations Conventional ductal proliferations Apocrine proliferations Mucinous proliferations Lobular proliferations Concepts basic to the analysis of papillary proliferations Papilloma Papillary carcinoma Micropapillary proliferations Concepts basic to the diagnosis of sclerosing lesions Sclerosing adenosis Radial scar Low grade invasive ductal carcinoma Concepts basic to the analysis of fibroepithelial lesions Fibroadenoma Myxoid fibroadenoma Phyllodes tumor Hamartoma and fibroadenoma variant Pseudoangiomatous stromal hyperplasia.

Practical Breast Pathology

Practical Breast Pathology Book
Author : Yan Peng,Ping Tang
Publisher : Springer
Release : 2019-07-18
ISBN : 3030165183
Language : En, Es, Fr & De

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Book Description :

This comprehensive volume reviews current topics and controversies in diagnostic breast pathology, and addresses frequently encountered diagnostic problems using a question and answer format and case presentations. Emphasis is placed on the diagnostic approach as it relates to morphology, clinical and radiographic correlation, differential diagnosis, and ancillary testing including immunohistochemical and molecular analyses. Answers are provided and serve as a practical, evidence-based, and problem solving guide to diagnostic issues having significant impacts on clinical management. Common but diagnostically challenging entities such as papillary lesions and fibroepithelial lesions are discussed in detail, as well as special types of breast cancer including solid papillary carcinoma, lobular lesions and its variants. Uncommon breast lesions such as mesenchymal, lymphoid, and metastatic lesions are also covered. Chapters discuss genetic alterations and molecular abnormalities in breast cancer, and commonly encountered interpretation dilemmas on immunohistochemistry in breast cancer and metastatic cancer to the breast with a focus on prognostic and predictive tumor biomarkers.

Biopsy Interpretation of the Breast

Biopsy Interpretation of the Breast Book
Author : Stuart J. Schnitt,Laura C. Collins
Publisher : Lippincott Williams & Wilkins
Release : 2012-10-08
ISBN : 1451178158
Language : En, Es, Fr & De

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Book Description :

A practical guide for the diagnostic surgical pathologist, this new edition of Biopsy Interpretation of the Breast presents the diverse spectrum of pathologic alterations that occur in the breast in a manner analogous to that in which they are encountered in daily practice. Lesions are grouped together according to their histologic patterns rather than by the traditional benign-malignant categorization in order to simulate the way pathologists face these lesions as they examine microscopic slides on a daily basis. The role of adjunctive studies in solving diagnostic problems in breast pathology is emphasized where appropriate. In addition, the clinical significance and impact on patient management of the various diagnoses are discussed and key clinical and management points highlighted.

Practical Surgical Pathology of the Breast

Practical Surgical Pathology of the Breast Book
Author : Juan P. Palazzo, MD
Publisher : Springer Publishing Company
Release : 2018-03-28
ISBN : 1617052833
Language : En, Es, Fr & De

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Book Description :

Practical Surgical Pathology of the Breast is a comprehensive and accessible guide for the practicing pathologist and trainee. It provides anatomic pathologists with the essential knowledge and tools to navigate breast cases and classification systems that are commonly and uncommonly found in everyday practice. Particularly challenging topics such as understanding the molecular mechanisms linked to breast cancer and the interpretation of molecular tests, are covered in clear prose, along with useful discussions on diagnostic challenges written by world experts. The use of immunohistochemistry in breast pathology is discussed in detail and how to apply it to resolve diagnostic problems. As a result, the book simplifies difficult-to-master issues such as recognizing therapy-induced changes to breast specimens and identifying borderline breast lesions and many more. Each chapter features high-quality images and stains, tables that emphasize differential diagnoses, text that highlight common diagnostic pitfalls with corresponding tips, as well as helpful key points and how to reach an accurate diagnosis using appropriate procedures and tests. With Practical Surgical Pathology of the Breast as a guide, practitioners and residents can hone their diagnostic skills, resolve difficult cases and improve their approach to breast cases in their daily practice. Key Features: Written by world-renowned breast pathology experts Emphasizes the differential diagnosis problem-solving process found in everyday practice Contains over 700 high-quality images including numerous immunohistochemical stains which are essential when comparing breast entities Includes detailed coverage of core biopsy interpretation, precursors of mammary carcinoma and their mimics, papillary lesions, flat epithelial atypia, adenosis, microinvasive carcinoma, carcinomas with good prognosis, mesenchymal lesions, triple negative carcinomas, lymphomas of the breast, and interpretation of therapy-related changes Highlights diagnostic pitfalls and common problems that a pathologist will encounter and includes practical tips throughout to guide the proper interpretation of breast lesions and the proper application of tests to reach accurate diagnoses

Difficult Diagnoses in Breast Pathology

Difficult Diagnoses in Breast Pathology Book
Author : Juan P. Palazzo, MD
Publisher : Demos Medical Publishing
Release : 2011-06-22
ISBN : 1935281305
Language : En, Es, Fr & De

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Book Description :

Breast cancer is the second leading cause of cancer death in women in the United States. For the pathologist, almost any breast lesion may produce diagnostic difficulty, especially due to frequently small samples (core biopsy specimens) and a variety of mimics and variants seen in specific types of lesions. Additionally, the difficulty of breast lesion diagnosis has risen dramatically in recent years due to the increased emphasis on stratifying patients for appropriate therapy on an individual basis; the wider range of both local and systemic therapeutic options, and the potential for earlier diagnosis through increased mammographic breast screening leading to a higher likelihood of a favorable outcome. Difficult Diagnoses in Breast Pathology provides a highly visual presentation of the major problems and questions that a pathologist is likely to encounter in the evaluation of common and uncommon breast diseases. Coverage includes needle core biopsy interpretation, diagnosis of precursor lesions, early stage disease, and recognition of neoplastic mimics and other misleading variants. In addition, this book emphasizes particularly difficult areas including the use of newer immunohistochemical markers. Throughout, the emphasis is on an easily accessible presentation with tables and lists of key points summarizing major findings and numerous high-quality images supporting the text. Difficult Diagnoses in Breast Pathology will be a valuable reference for every pathologist who deals with the diagnosis of breast diseases. Difficult Diagnoses in Breast Pathology Features: Each chapter authored by recognized expert in the area Hundreds of high-quality images Tables and key points in each chapter summarize the most important findings Coverage based on addressing in detail the real-world diagnostic problems the pathologist will face in daily practice

Breast Pathology in Clinical Practice

Breast Pathology in Clinical Practice Book
Author : Sami Shousha
Publisher : Springer Nature
Release : 2020-07-01
ISBN : 3030423867
Language : En, Es, Fr & De

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Book Description :

This book provides a concise, step-by-step guide to accurate microscopic diagnosis for clinicians who deal with patients with breast lesions. The emphasis is on a practical approach to dealing with breast biopsies and reaching a diagnosis. It outlines the procedures used for the microscopic diagnosis of various breast lesions and the significance of the nomenclature and terms used in pathology reports, including those dealing with uncommon or rare lesions. Ample illustrations of the lesions discussed are included, particularly those dealing with uncommon and border-line lesions. There is a special emphasis on breast cancer and on the fact that not all breast cancers are the same. The different ways by which breast cancers are classified are discussed including recent classifications which lead to personalized therapy. The book is aimed at pathologists of all grades who deal with breast biopsies including those in training. It would be also useful for practicing and trainee surgeons and oncologists as well as other health professionals dealing with patients with breast diseases and scientists carrying out research on breast problems.

Rosen s Breast Pathology

Rosen s Breast Pathology Book
Author : Paul Peter Rosen
Publisher : Lippincott Williams & Wilkins
Release : 2009
ISBN : 0781771374
Language : En, Es, Fr & De

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Book Description :

Written by an internationally recognized expert in diagnostic breast pathology, this gold-standard text and reference is now in its revised, updated, and expanded Third Edition. It provides a comprehensive, extensively illustrated review of the clinical, radiological, pathological, and therapeutic aspects of the entire spectrum of breast diseases. More than 3,000 full-color illustrations—1,200 new to this edition—provide the true-to-life perspective essential to accurate diagnosis, prognosis, and management. Highlights of this edition include updated information on immunohistochemistry, molecular diagnostics, tissue microarrays, and gene expression profiling; discussion of the advantages and disadvantages of needle core biopsy; descriptions of basal-like carcinoma; and a greatly expanded discussion of pathological and clinical controversies regarding sentinel lymph node mapping. A companion Website will offer the fully searchable text and an image bank.

Mesenchymal Tumors of the Breast and Their Mimics

Mesenchymal Tumors of the Breast and Their Mimics Book
Author : J. Jordi Rowe,Erinn Downs-Kelly
Publisher : Springer Nature
Release : 2021-07-31
ISBN : 3030744744
Language : En, Es, Fr & De

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Book Description :

This book utilizes a uniform approach to provide a framework for the diagnosis of mesenchymal tumors of the breast while highlighting their mimics. Emphasis is placed on a practical approach to the morphologic interpretation and useful ancillary tests while exploring the differential diagnoses in depth. Given the overall low incidence of mesenchymal lesions of the breast along with their mimics, surgical pathologists are not consistently exposed to these spindle cell lesions. Compounding this problem is the broad differential that these lesions engender, with entities ranging from reactive/reparative lesions to poorly differentiated spindle cell malignancies. Furthering the challenge, the diagnoses may be complicated by fixation issues, sampling method, small sample size, lack of clinical history and prior treatment effects. The goal of this book is to introduce readers to the spectrum of these lesions while providing a systematic approach that helps establish accurate diagnoses that in turn drive appropriate clinical follow up and treatment. Chapters cover the spectrum of benign and malignant mesenchymal tumors and their mimics that are found in the breast in an easy to read format with richly detailed images to aid in diagnoses. The text also discusses practical components to aid in establishing and evaluating the differential diagnosis. Given how morphologically and clinically diverse these lesions are, Mesenchymal Tumors of the Breast and Their Mimics provides a construct for integrating the varied components that go into establishing a diagnosis for this challenging aspect of breast pathology.

Breast Pathology

Breast Pathology Book
Author : Paul Peter Rosen,Syed A. Hoda
Publisher : Lippincott Williams & Wilkins
Release : 2010
ISBN : 160831670X
Language : En, Es, Fr & De

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Book Description :

Edited by two eminent authorities on breast pathology, this heavily illustrated text offers essential guidance on diagnostic evaluation of needle core biopsies. More than 1,100 full-color illustrations depict the entire spectrum of breast pathology seen in needle core biopsies.

Breast Pathology

Breast Pathology Book
Author : Paul Peter Rosen,Syed A. Hoda
Publisher : Unknown
Release : 2006
ISBN : 9780781760942
Language : En, Es, Fr & De

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Book Description :

Edited by two eminent authorities on breast pathology, this heavily illustrated text offers essential guidance on diagnostic evaluation of needle core biopsies. The focus is on the most common and challenging differential diagnostic problems encountered in these specimens. More than 1,000 full-color illustrations depict the entire spectrum of breast pathology seen in needle core biopsies. This edition includes many new cases and illustrations, discussions on the growing importance of immunopathology, and updated guidelines on pathologic examination and reporting of needle core biopsy specimens. Contributions by two well-known radiologists present state-of-the-art information on the techniques and clinical impact of imaging-guided needle core biopsy.

Practical Breast Pathology

Practical Breast Pathology Book
Author : Tibor Tot,Laszlo Tabar,Peter B. Dean
Publisher : Thieme
Release : 2014-04-30
ISBN : 3131607823
Language : En, Es, Fr & De

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Book Description :

Acclaim for the first edition: Succinct, well organized, and easy-to-followof the highest qualityrecommended. -- Radiology Excellent histologic illustrations and concise textprovides a firm foundation in fundamental concepts.-- American Journal of Roentgenology Remarkablesplendid illustrations provide large views of the lesionsgood reference for any clinician interested in breast pathology. -- Surgical and Radiologic Anatomy Focused on a modern, interdisciplinary approach to diagnosing and managing diseases of the breast, this concise book builds on the high standard set in the previous edition. It provides a complete foundation in the basic principles, radiologic appearance and underlying pathology of breast disease, without overwhelming non-pathologist members of the team with excessive detail. For effective communication at every level, Practical Breast Pathology, Second Editionprovides the clear information, case examples and superb illustrations that make it an ideal clinical problem solver. Special features of the second edition: High-quality examples of modern multimodality radiology (digital mammography, ultrasound and magnetic resonance imaging) correlated with large-format 2D and 3D histologic slides New findings on such clinically important topics as the lobar nature of breast carcinoma, multifocality, diffuse carcinomas and extent of disease, concept of the sick lobe and more Introduction of the molecular classification of invasive breast cancer Discussion of prognostic and predictive factors in breast carcinoma, such as hormone receptors and HER2 status Updates on preoperative diagnosis, including intact biopsy and radiologic assessment of the extent and distribution of lesions Enriched with new information and stunning illustrations in every chapter, Practical Breast Pathology, Second Edition is a key link in the exchange between pathologists, radiologists, oncologists and breast surgeons, as well as residents and trainees. It provides an essential framework for understanding the mammographic-pathologic correlation, leading to increased cooperation among clinical team members and significantly improved outcomes for patients.

Atlas of Breast Pathology

Atlas of Breast Pathology Book
Author : Steven G. Silverberg
Publisher : Saunders
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This color atlas covers a range of breast pathology, both benign and malignant. Emphasis is on practical differential diagnosis, and detailed guidance is provided for the submission, examination, and reporting of different types of breast specimens and their diagnosis. Chapters are devoted to the radiographic appearance and the cytopathologic features of breast lesions, and to communication between the pathologist and the other clinical members of the breast cancer management team. The book can be used a reference for specific subjects and as a primer on breast pathology for both pathology residents and nonpathologist physicians. Color and b & w medical images on every page illustrate conditions. Silverberg is a pathologist affiliated with the U. of Maryland School of Medicine and the U. of Maryland Medical Center. Annotation copyrighted by Book News, Inc., Portland, OR

Intraoperative Frozen Sections

Intraoperative Frozen Sections Book
Author : Pedram Argani, MD,Ashley Cimino-Mathews, MD
Publisher : Demos Medical Publishing
Release : 2013-07-15
ISBN : 1936287978
Language : En, Es, Fr & De

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Book Description :

Intraoperative Frozen Sections presents diagnostic challenges involved in the evaluation in the pathology lab of specimens obtained during surgery through the case experience of expert pathologists. Sixty-three problems cover the wide range of problems encountered in intraoperative consultations. Each presentation provides the case information as presented to the consultant, the evaluation and analysis of the specimen, discussion of the results and teaching points observed in the case, and an overall comment providing additional context for the diagnostic problem that has been presented. This problem-oriented format makes the book a superb reference resource for the working diagnostician and an ideal teaching tool for the resident or fellow. Coverage includes pediatric specimens and there is a section describing recognition of artifacts. Each case presentation is supported by several high-quality color photomicrographs with detailed explanations of each image, including images of the permanent sections and immunostains where applicable. Features of Intraoperative Frozen Sections include: Cases outline expert approach to diagnostic problems and technical issues most likely to be encountered in frozen section analysis Coverage includes pediatric specimens and recognition of artifacts Special emphasis on difficult problems and avoiding diagnostic pitfalls Provides common differential diagnoses for specific lesions seen in frozen section analysis (e.g. mimics of renal neoplasia) Nearly 500 high-quality color photomicrographs and detailed discussions of diagnostic features of each image "

Breast Pathology

Breast Pathology Book
Author : Frances P. O'Malley,Sarah E. Pinder,Anna Marie Mulligan
Publisher : Saunders
Release : 2011
ISBN : 9781437717570
Language : En, Es, Fr & De

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Book Description :

Breast Pathology, a title in the Foundations in Diagnostic Pathology series, provides all of the most essential information on the pathological entities encountered in practice in an easy-to-use format. Drs. Frances P. O'Malley, Sarah E. Pinder, and Anna Marie Mulligan provide unparalleled expert guidance for the study and diagnosis of a broad spectrum of breast lesions as well as the broad range of appearances of normal breast tissue. The consistent, practical format with a wealth of illustrations, at-a-glance boxes, and tables, along with online access at www.expertconsult.com, make this title ideal for quick reference for both novices and experienced breast pathologists Reference key information quickly and easily with a consistent, user-friendly format and at-a-glance boxes and tables throughout the text. Examine all aspects of a pathologic entity, including clinical features, pathologic features (gross and microscopic), ancillary studies, differential diagnosis, and prognostic and therapeutic considerations. Catch all the nuances of how pathological lesions present through over 400 full-color illustrations. Practice with confidence and overcome your toughest challenges with advice from the top minds in breast pathology. Access the fully searchable text online at www.expertconsult.com, along with a downloadable image bank, illustrations, boxes, tables, and more. Apply the latest molecular diagnostic techniques to recognize newly identified classifications in breast disease. Get more of the information you need from new and expanded chapters covering a broad range of diseases and topics including fine needle aspiration cytology and the physical handling of core biopsy specimens; handling and evaluation of sentinel lymph nodes; diseases of the male breast; and state-of-the-art coverage of molecular advances in malignant breast disease. Prepare for the future of breast pathology with a new chapter dedicated to gene profiling and stem cell diagnostic techniques. A quick and easy to use reference, as a refresher or for those just starting out, on breast pathology.

Essentials of Diagnostic Breast Pathology

Essentials of Diagnostic Breast Pathology Book
Author : Farid Moinfar
Publisher : Springer Science & Business Media
Release : 2007-08-10
ISBN : 354045120X
Language : En, Es, Fr & De

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Book Description :

This abundantly illustrated reference focuses on the essential information needed by pathologists in order to interpret breast lesions (tumors) appropriately. Particular attention is paid to the diagnostic criteria with systematic analysis of differential diagnoses. Value and limitations of immunohistochemistry as a diagnostic adjunct are demonstrated as well. The presentation is structured for quick retrieval of information.

Evidence Based Pathology and Laboratory Medicine

Evidence Based Pathology and Laboratory Medicine Book
Author : Alberto M. Marchevsky,Mark Wick
Publisher : Springer Science & Business Media
Release : 2011-07-01
ISBN : 9781441910301
Language : En, Es, Fr & De

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Book Description :

Focusing on practical, patient related issues, this volume provides the basic concepts of Evidence Based Medicine (EBM) as they relate to Pathology and Laboratory Medicine and presents various practical applications. It includes EBM concepts for use in the identification of cost-effective panels of immunostains and other laboratory tests and for improvement of diagnostic accuracy based on the identification of selected diagnostic features for particular differential diagnosis. EBM concepts are also put forth for use in Meta-analysis to integrate the results of conflicting literature reports and use of novel analytical tools such as Bayesian belief networks, neural networks, multivariate statistics and decision tree analysis for the development of new diagnostic and prognostic models for the evaluation of patients. This volume will be of great value to pathologists who will benefit from the concepts being promoted by EBM, such as levels of evidence, use of Bayesian statistics to develop diagnostic and other rules and stronger reliance on "hard data" to support therapeutic and diagnostic modalities.

Pathology A Modern Case Study

Pathology  A Modern Case Study Book
Author : Howard Reisner
Publisher : McGraw Hill Professional
Release : 2014-09-22
ISBN : 0071821236
Language : En, Es, Fr & De

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Book Description :

A unique case-based molecular approach to understanding pathology Pathology: A Modern Case Study is a concise, focused text that emphasizes the molecular and cellular biology essential to understanding the concepts of disease causation. The book includes numerous case studies designed to highlight the role of the pathologist in the team that provides patient care. Pathology: A Modern Case Study examines the role of anatomic, clinical, and molecular pathologists in dedicated chapters and in descriptions of the pathology of specific organ systems. Features Coverage of pathology focuses on modern approaches to common and important diseases Each chapter delivers the most up-to-date advances in pathology Learning aids include chapter summaries and overviews, bolded terms, and a glossary Common clinically relevant disease are highlighted Disease discussion is based on organ compartment and etiology Coverage includes: Disease and the Genome: Genetic, Developmental and Neoplastic Disease Cell Injury, Death and Aging and the Body's Response Environmental Injury Clinical Practice: Anatomic Pathology Clinical Practice: Molecular Pathology Clinical Practice: Molecular Pathology Organ-specific pathology covering all major body systems Molecular pathology Essential for undergraduate medical students and clinicians who wish to expand their knowledge pathology, Pathology: A Modern Case Study delivers valuable coverage that is directly related to a patient’s condition and the clinical practice of pathology.

WHO Classification of Tumours of the Breast

WHO Classification of Tumours of the Breast Book
Author : Sunil R. Lakhani,International Agency for Research on Cancer
Publisher : World Health Organization
Release : 2012
ISBN : 9789283224334
Language : En, Es, Fr & De

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Book Description :

WHO Classification of Tumours of the Breast is the fourth volume of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors. The book, prepared by 90 authors from 24 countries, contains more than 340 colour photographs, tables and figures, and more than 1600 references.

Diagnostic Histopathology of the Breast

Diagnostic Histopathology of the Breast Book
Author : David L. Page,Thomas J. Anderson
Publisher : W.B. Saunders Company
Release : 1987
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Written in order to promote the use of histopathology in the study and clinical management of breast disease, this aims to bring consistency to concepts in terminology and to present recognizable patterns in the context of their clinical significance.

Breast Pathology

Breast Pathology Book
Author : Sami Shousha
Publisher : Springer
Release : 2016-11-24
ISBN : 3319286552
Language : En, Es, Fr & De

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Book Description :

​This book covers practical diagnostic issues in breast pathology, with special emphasis on areas which pose diagnostic difficulties. These include dealing with the gross specimens derived from patients treated with conservative surgery and those who had neo-adjuvant therapy before surgery. It also discusses how to deal with axillary lymph nodes, proliferative breast lesions, including DCIS, and problematic core biopsies, as well as fibro-epithelial, spindle cell, lobular, mucinous, metaplastic and papillary lesions, molecular classification of breast cancers, breast lesions in male patients and breast immunohistochemistry. There is a focus on unusual benign and malignant breast lesions and a large number of high-quality images help the reader diagnose difficult cases. Breast Pathology: Problematic Issues is aimed at histopathology consultants and senior trainees who deal with breast pathology.