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Diagnosis And Management Of Hereditary Cancer

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Diagnosis and Management of Hereditary Cancer

Diagnosis and Management of Hereditary Cancer Book
Author : John W. Henson,Robert G Resta
Publisher : Academic Press
Release : 2021-03-20
ISBN : 0323885829
Language : En, Es, Fr & De

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Book Description :

Many hereditary cancer syndromes are linked to alterations in single genes. Detection and clinical interpretation of these alterations can guide cancer risk reduction for patients and their families through screening, prophylactic measures, and other strategies. Diagnosis and Management of Hereditary Cancer summarizes hereditary syndromes and their associated cancers and genes. The information is presented in 50 practice-enhancing tables that relate clinical, genetic, diagnostic, and management aspects in a manner that has previously not been available in a single reference. Intended to guide the specialist as well the novice, this volume will elevate the care of hereditary cancer patients and their families. Unique table-based presentation of 50 key aspects of hereditary cancer Clinical features, genetics, genetic testing, diagnosis, counseling, and management of multiple hereditary cancer syndromes Table-based format to inter-relate clinical and scientific information Landscape layout for easier viewing of tabular information

Rare Hereditary Cancers

Rare Hereditary Cancers Book
Author : Gabriella Pichert,Chris Jacobs
Publisher : Springer
Release : 2016-04-13
ISBN : 3319299980
Language : En, Es, Fr & De

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Book Description :

This book approaches the differential diagnosis and management of rare, hereditary cancer syndromes from a practical angle, addressing the issues pertinent to each tumour type as encountered by health professionals in their day-to-day practice. This book enables readers to correctly identify patients with rare cancer syndromes who would benefit from genetic counselling and testing, and provides the necessary knowledge for appropriate patient management and advising at-risk family members. It begins by describing recent advances in genetic testing for cancer-predisposing genes. Leading experts from Europe and Australia then offer detailed, up-to-date guidance on the diagnosis and management of a wide range of hereditary cancers. The concluding chapter examines the wider issues that are raised by genetic testing for rare cancer syndromes for patients, families and health professionals. This book is an invaluable source of information for all specialists involved in the care of such patients and their families.

Rare Hereditary Cancers

Rare Hereditary Cancers Book
Author : Gabriella Pichert,Chris Jacobs
Publisher : Springer
Release : 2016-04-02
ISBN : 9783319299969
Language : En, Es, Fr & De

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Book Description :

This book approaches the differential diagnosis and management of rare, hereditary cancer syndromes from a practical angle, addressing the issues pertinent to each tumour type as encountered by health professionals in their day-to-day practice. This book enables readers to correctly identify patients with rare cancer syndromes who would benefit from genetic counselling and testing, and provides the necessary knowledge for appropriate patient management and advising at-risk family members. It begins by describing recent advances in genetic testing for cancer-predisposing genes. Leading experts from Europe and Australia then offer detailed, up-to-date guidance on the diagnosis and management of a wide range of hereditary cancers. The concluding chapter examines the wider issues that are raised by genetic testing for rare cancer syndromes for patients, families and health professionals. This book is an invaluable source of information for all specialists involved in the care of such patients and their families.

Diagnostic Pathology Familial Cancer Syndromes E Book

Diagnostic Pathology  Familial Cancer Syndromes E Book Book
Author : Vania Nosé
Publisher : Elsevier Health Sciences
Release : 2020-02-14
ISBN : 0323712053
Language : En, Es, Fr & De

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Book Description :

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Physicians should have the knowledge derived from morphological findings to identify the likelihood of a cancer patient having an additional underlying familial syndrome— and to decide if that patient should undergo molecular genetic evaluation. This volume is specifically designed to help pathologists, oncologists, and other physicians who diagnose and treat cancer to recognize syndromes and syndrome- associated neoplasms and advise patients and their families on the possibility of a familial syndrome and their risk of developing other tumors. Diagnostic Pathology: Familial Cancer Syndromes, second edition, is an easy-to-use, one-stop reference for information on hereditary cancer syndromes, including differential diagnosis and management, that offers a templated, highly formatted design; concise, bulleted text; and superior color images throughout. Contains all the information necessary to determine whether a neoplasm typically encountered in daily practice is sporadic or related to a familial cancer syndrome Features a revised structure to keep you up to date: Part I includes more than 80 detailed chapters describing diagnoses associated with familial cancer syndromes; Part II contains more than 70 chapters with detailed descriptions of major syndromes (cross-referenced with diagnoses); and Part III features a molecular factors index that includes a complete description of each known gene associated with a familial cancer syndrome Contains updated chapters with newly classified GI, neurology, multiple organ, eye, endocrine, GYN, and kidney tumors, as well as more than 20 entirely new chapters covering recently recognized syndromes Incorporates up-to-date molecular findings and their significance for familial cancer syndromes; new techniques and technologies being used to discover gene mutations and other alterations; and details on personalized medicine targeted to specific genes Features more than 2,200 images throughout, including clinical and radiological images, algorithms, graphics, gross pathology, histology, and a wide range of special and immunohistochemical stains—all carefully annotated to highlight the most diagnostically significant factors Features time-saving bulleted text, key facts in each chapter, an extensive index, and numerous tables for quick reference and thorough understanding

Hereditary Colorectal Cancer

Hereditary Colorectal Cancer Book
Author : Miguel A. Rodriguez-Bigas,Raul Cutait,Patrick M. Lynch,Ian Tomlinson,Hans F.A. Vasen
Publisher : Springer Science & Business Media
Release : 2010-09-10
ISBN : 9781441966032
Language : En, Es, Fr & De

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Book Description :

Colorectal cancer is the third most commonly diagnosed cancer in the US and the third most recently linked to cancer deaths. The national annual incidence rate of colorectal cancer is approximately 148,000+, striking slightly more females than males. The lifetime risk of colorectal cancer is 5-6%, however patients with a familial risk (with two or more first or second degree relatives) make up 20% of the patients. Persons who carry genetic mutations linked to hereditary colorectal cancer are the most likely to develop the disease.

Intestinal Polyposis Syndromes

Intestinal Polyposis Syndromes Book
Author : Lisa A. Boardman
Publisher : Springer
Release : 2016-03-08
ISBN : 3319281038
Language : En, Es, Fr & De

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Book Description :

This book provides a comprehensive, state-of-the art review of intestinal polyposis syndromes. The book reviews the most up-to-date clinical, management, and genetic information regarding the continually evolving colorectal condition that manifests as a polyposis condition. It provides a reference for clinicians and researchers in understanding the complexity of intestinal polyposis and the importance of utilizing multiple modalities for the diagnosis, management and control of these conditions. It also provides an overview of what should alert a care provider to the possibility of a polyposis syndrome. Written by experts in their fields, Intestinal Polyposis Syndromes: Diagnosis and Management is a valuable resource for physicians and researchers who deal with the challenges of diagnosing and managing colorectal cancer and intestinal polyposis syndromes.

Diagnostic Pathology Familial Cancer Syndromes

Diagnostic Pathology  Familial Cancer Syndromes Book
Author : Vania Nos?
Publisher : Elsevier
Release : 2020-02-03
ISBN : 9780323712040
Language : En, Es, Fr & De

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Book Description :

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Physicians should have the knowledge derived from morphological findings to identify the likelihood of a cancer patient having an additional underlying familial syndrome- and to decide if that patient should undergo molecular genetic evaluation. This volume is specifically designed to help pathologists, oncologists, and other physicians who diagnose and treat cancer to recognize syndromes and syndrome- associated neoplasms and advise patients and their families on the possibility of a familial syndrome and their risk of developing other tumors. Diagnostic Pathology: Familial Cancer Syndromes, second edition, is an easy-to-use, one-stop reference for information on hereditary cancer syndromes, including differential diagnosis and management, that offers a templated, highly formatted design; concise, bulleted text; and superior color images throughout.

Inherited Cancer Syndromes

Inherited Cancer Syndromes Book
Author : C. Neal Ellis
Publisher : Springer Science & Business Media
Release : 2010-10-29
ISBN : 9781441968210
Language : En, Es, Fr & De

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Book Description :

The second edition of Inherited Cancer Syndromes incorporates new genetic markers data with the clinical utility and practicality of the first edition.

Hereditary Tumors

Hereditary Tumors Book
Author : Heike Allgayer,Helga Rehder,Simone Fulda
Publisher : John Wiley & Sons
Release : 2009-05-13
ISBN : 3527627537
Language : En, Es, Fr & De

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Book Description :

Summarizing molecular aspects, diagnostic as well as therapeutic issues, this book is the very first and most comprehensive on hereditary aspects of tumor diseases. All the contributors have been made fellows of the Ingrid zu Solms Foundation due to their outstanding achievements in scientific research, and they discuss here the latest aspects in the diagnosis, disease management, and treatment of hereditary tumor diseases and syndromes. A must-have ready reference for medical and biology students, MDs, PhDs, physicians, and researchers.

Familial Cancer and Prevention

Familial Cancer and Prevention Book
Author : Joji Utsunomiya,John J. Mulvihill,Walter Weber
Publisher : John Wiley & Sons
Release : 1999-04-27
ISBN : 9780471249375
Language : En, Es, Fr & De

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Book Description :

A New Strategy Toward Cancer Control. Still in its infancy, the familial/hereditary approach to cancer control is proving to be one of the most potent strategies in the war on cancer. Over the past few years the human genome project has generated an abundance of valuable information on the genetic origins of a range of cancers. Tests now exist for several hereditary, tumor-promoting genetic mutations-including those found in BRCA genes associated with breast cancer as well as mutations of HNPCC genes which have been linked to colon cancers-and many more are anticipated in the near future. Armed with the information yielded by these tests, physicians have already saved countless lives through preventative counseling, early detection, and more highly-focused intervention strategies. Inspired by the proceedings of the UICC 1997 Symposium on Familial Cancer and Prevention held in Kobe, Japan, this volume provides clinicians and researchers with a detailed review of the latest developments at the front lines of the familial cancer prevention movement. In a series of edited contributions, leading researchers and clinicians from around the globe summarize their experiences and analyze current and emerging trends in: * Information gathering and history taking. * Risk assessment. * Genetic testing for colorectal, endocrine, breast, and other familial cancers. * Diagnosis, prognosis, and management of an array of familial cancers. * Genetic counseling for familial cancers. Up-to-date, authoritative, and comprehensive, Familial Cancer and Prevention is an important working resource for clinicians, cancer researchers, and epidemiologists.

Glass s Office Gynecology

Glass s Office Gynecology Book
Author : Robert H. Glass,Michèle G. Curtis,Michael P. Hopkins
Publisher : Lippincott Williams & Wilkins
Release : 1999
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Glass s Office Gynecology book written by Robert H. Glass,Michèle G. Curtis,Michael P. Hopkins, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Hereditary Colorectal Cancer

Hereditary Colorectal Cancer Book
Author : Laura Valle,Stephen B. Gruber,Gabriel Capellá
Publisher : Springer
Release : 2018-05-04
ISBN : 3319742590
Language : En, Es, Fr & De

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Book Description :

This book provides information on a wide variety of issues ranging from genetics to clinical description of the syndromes, genetic testing and counseling, and clinical management including surveillance, surgical and prophylactic interventions, and chemoprevention. Moreover, current hot issues, such as the identification of novel causal genes and the challenges we face, and the relevance of cancer risk modifiers, both genetic and environmental, are also discussed. This reference book is great for geneticists, oncologists, genetic counselors, researchers, clinicians, surgeons and nurses dedicated to, or interested in, hereditary cancer. The best and most recognized experts in the field have contributed to this project, guaranteeing updated information, accuracy and the discussion of topical issues.

The Role of Genetic Testing in Surgical Oncology An Issue of Surgical Oncology Clinics of North America

The Role of Genetic Testing in Surgical Oncology  An Issue of Surgical Oncology Clinics of North America  Book
Author : Thomas K. Weber
Publisher : Elsevier Health Sciences
Release : 2016-01-07
ISBN : 0323401090
Language : En, Es, Fr & De

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Book Description :

This issue of Surgical Oncology Clinics of North America, edited by Thomas Weber, MD, is devoted to Genetic Testing in Surgical Oncology. Articles in this issue include: The Critical Importance of Timely Genetic Testing; Securing and Documenting Cancer Family History in the Age of the Electronic Medical Record; Cancer Family Registries: Vital Tools for Patient Management and Cancer Genetics Translational Research; The Genetics of Breast Cancer; The Genetics of Colorectal Cancer: HNPCC, FAP MYH, and Hamartomatous Syndromes Including Peutz-Jeghers and Jevenile Polyposis; Hereditary Gastric Cancer Syndromes; Hereditary Pancreatic Cancer Syndromes; Hereditary Melanoma: Genetics and Multidisciplinary Management; Multiple Endocrine Neoplasia: Genetics and Clinical Management; Sequence Variants of Uncertain Significance (VUS): What To Do When Genetic Testing Results Are Not Definitive; Confidentiality and the Risk of Genetic Discrimination: What Surgeons Need to Know; and A Certified Genetic Counselor: A Crucial Clinical Resource in the Management of Patients with Suspected Hereditary Solid Tumor Syndromes.

Advances in Diagnosis and Management of Ovarian Cancer

Advances in Diagnosis and Management of Ovarian Cancer Book
Author : Samir A. Farghaly
Publisher : Springer
Release : 2016-08-23
ISBN : 9781489979384
Language : En, Es, Fr & De

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Book Description :

Ovarian Cancer: Advances in Diagnosis and Management presents unique international perspectives on this devastating disease. While ovarian cancer has mainly been considered a disease of the Western hemisphere, this book moves beyond our conventional understanding and embraces knowledge from around the world. The focus is on recent advances in diagnosis, including genetic screening, and improvements and expanded choices in management, such as the optimization of chemotherapeutic agents, gene therapy, and the latest laparoscopic and robotic surgical techniques. Further chapters address psychosocial and quality-of-life issues. This book is an excellent resource on the international state-of-the-art in the diagnosis and management of ovarian cancer and is aimed at oncologists, gynecologists, and fellows.

Medical Genetics at a Glance

Medical Genetics at a Glance Book
Author : Dorian J. Pritchard,Bruce R. Korf
Publisher : John Wiley & Sons
Release : 2013-07-08
ISBN : 1118689011
Language : En, Es, Fr & De

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Book Description :

Medical Genetics at a Glance covers the core scientificprinciples necessary for an understanding of medical genetics andits clinical applications, while also considering the socialimplications of genetic disorders. This third edition has been fully updated to include the latestdevelopments in the field, covering the most common geneticanomalies, their diagnosis and management, in clear, concise andrevision-friendly sections to complement any health sciencecourse. Medical Genetics at a Glance now has a completely revisedstructure, to make its content even more accessible. Other featuresinclude: • Three new chapters on Gene Identification, The Biologyof Cancer, and Genomic Approaches to Cancer • A much extended treatment of BiochemicalGenetics • A completely revised chapter on The Cell Cycle,explaining principles of biochemistry and genetics which arefundamental to understanding cancer causation • Two new chapters on Cardiac DevelopmentalPathology • An extended Case Studies section Providing a broad understanding of one of the most rapidlyprogressing topics in medicine, Medical Genetics at a Glanceis perfect for students of medicine, molecular biology, geneticsand genetic counselling, and is a previous winner of a BMAAward.

Familial Breast and Ovarian Cancer

Familial Breast and Ovarian Cancer Book
Author : Patrick J. Morrison,Shirley V. Hodgson,Neva E. Haites
Publisher : Cambridge University Press
Release : 2002-11-07
ISBN : 9781139437721
Language : En, Es, Fr & De

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Book Description :

This publication surveys the profound and far-reaching ramifications that have arisen from the very significant advances in our understanding of the genetic basis of familial breast and ovarian cancer. Written by international experts from Europe and North America, this book provides the busy clinician with a contemporary and wide-ranging guide to the latest developments in the diagnosis, genetics, screening, prevention and management of familial breast cancer. This area has advanced in knowledge so rapidly that this publication provides an unrivalled source of information including sections on ethical and insurance issues and the different cultural differences in breast cancer. The use of recently devised cancer genetics clinics and different referral criteria and patterns to these clinics are detailed. The volume will be of immense value to all clinical geneticists, oncologists, and healthcare professionals involved in screening and counselling programmes.

Inherited Cancer Syndromes

Inherited Cancer Syndromes Book
Author : Neal C. Jr. Ellis
Publisher : Springer Science & Business Media
Release : 2007-05-08
ISBN : 0387215964
Language : En, Es, Fr & De

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Book Description :

Of the 8 million individuals living with cancer in the United States, up to 800,000 patients have a form of inherited cancer. Inherited cancer syndromes account for 5-10% of all cancers, as evidenced by recent advances in the understanding of such syndromes as Familial Polyposis Syndromes (FAP), Hereditary Nonpolyposis Colon Cancer (HPNCC), and the BRCA1 and 2 breast cancer susceptibility genes. Inherited Cancer Syndromes: Current Clinical Management provides the clinician with a valuable tool for all aspects of patient care in inherited syndromes. Comprehensive, timely chapters present the fundamental principles of genetic counseling and testing, ethical issues, medical-legal issues, and clinical management principles. Chapters on inherited breast cancer, colon cancer, urologic malignancies, gynecologic malignancies, and MEN syndromes provide state-of-the-art information on hereditary risk identification, assessment and management, the role of the genetic counselor, providing optimal patient care, and the important research on the horizon - all written by an expert group of surgical and medical oncologists. Inherited Cancer Syndromes: Current Clinical Management is an important and timely book for surgical oncologists, medical oncologists, radiation oncologists, general surgeons, colorectal surgeons, trainees in surgery and oncology, and genetic counselors.

Familial Cancer Management

Familial Cancer Management Book
Author : Walter Weber,John J. Mulvihill, M.D.,Steven A. Narod
Publisher : CRC Press
Release : 1996-01-24
ISBN : 9780849347825
Language : En, Es, Fr & De

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Book Description :

Familial Cancer Management addresses familial cancer patterns, a rapidly expanding field of investigation resulting from recent significant advances in molecular genetics. It encompasses etiological and pathological aspects of familial cancer clustering, the description of frequent and important family syndromes, diagnostic procedures, and principles of counseling, prevention, and management. This unique and thorough text also discusses important ethical and legal issues and identifies familial cancer assessment services. Familial Cancer Management is written for health care professionals enabling them to identify and manage familial cancer occurrences.

Principles of Clinical Cancer Genetics

Principles of Clinical Cancer Genetics Book
Author : Daniel C. Chung,Daniel A. Haber
Publisher : Springer Science & Business Media
Release : 2010-07-20
ISBN : 9780387938462
Language : En, Es, Fr & De

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Book Description :

Advances in genetics are transforming estimates of an individual’s risk of developing cancer and approaches to prevention and management of cancer in those who may have increased susceptibility. Identifying and caring for patients with hereditary cancer syndromes and their family members present a complex clinical, scientific and social challenge. This textbook, by leading experts at Massachusetts General Hospital Cancer Center, highlights the current understanding of the genetics of hereditary cancers of the breast, ovary, colorectum, stomach, pancreas, kidney, skin, and endocrine organs. Practical guidelines for the use of genetic testing, cancer screening and surveillance, prophylactic surgery, and promising targeted therapeutic agents are discussed. In addition, ongoing research involving genome-wide screens to identify novel modest risk-associated genetic loci are explored, along with new approaches to the application of genetic markers in guiding therapeutic options.

Familial Cancer New Insights for the Healthcare Professional 2012 Edition

Familial Cancer  New Insights for the Healthcare Professional  2012 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-12-10
ISBN : 1464973717
Language : En, Es, Fr & De

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Book Description :

Familial Cancer: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Familial Cancer in a concise format. The editors have built Familial Cancer: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Familial Cancer in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Familial Cancer: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.