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Deterministic Versus Stochastic Modelling In Biochemistry And Systems Biology

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Deterministic Versus Stochastic Modelling in Biochemistry and Systems Biology

Deterministic Versus Stochastic Modelling in Biochemistry and Systems Biology Book
Author : Paola Lecca,Ian Laurenzi,Ferenc Jordan
Publisher : Elsevier
Release : 2013-04-09
ISBN : 1908818212
Language : En, Es, Fr & De

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Book Description :

Stochastic kinetic methods are currently considered to be the most realistic and elegant means of representing and simulating the dynamics of biochemical and biological networks. Deterministic versus stochastic modelling in biochemistry and systems biology introduces and critically reviews the deterministic and stochastic foundations of biochemical kinetics, covering applied stochastic process theory for application in the field of modelling and simulation of biological processes at the molecular scale. Following an overview of deterministic chemical kinetics and the stochastic approach to biochemical kinetics, the book goes onto discuss the specifics of stochastic simulation algorithms, modelling in systems biology and the structure of biochemical models. Later chapters cover reaction-diffusion systems, and provide an analysis of the Kinfer and BlenX software systems. The final chapter looks at simulation of ecodynamics and food web dynamics. Introduces mathematical concepts and formalisms of deterministic and stochastic modelling through clear and simple examples Presents recently developed discrete stochastic formalisms for modelling biological systems and processes Describes and applies stochastic simulation algorithms to implement a stochastic formulation of biochemical and biological kinetics

Synthetic Biology a Primer revised Edition

Synthetic Biology   a Primer  revised Edition  Book
Author : Paul S. FREEMONT,Richard I. KITNEY
Publisher : World Scientific
Release : 2015-08-24
ISBN : 1783268808
Language : En, Es, Fr & De

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Book Description :

Download Synthetic Biology a Primer revised Edition book written by Paul S. FREEMONT,Richard I. KITNEY, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Computational Systems Biology

Computational Systems Biology Book
Author : Jean-Christophe Leloup,Didier Gonze,Albert Goldbeter
Publisher : Elsevier Inc. Chapters
Release : 2013-11-26
ISBN : 0128070110
Language : En, Es, Fr & De

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Book Description :

Circadian rhythms originate from intertwined feedback processes in genetic regulatory networks. Computational models of increasing complexity have been proposed for the molecular mechanism of these rhythms, which occur spontaneously with a period on the order of 24h. We show that deterministic models for circadian rhythms in Drosophila account for a variety of dynamical properties, such as phase shifting or long-term suppression by light pulses and entrainment by light/dark cycles. Stochastic versions of these models allow us to examine how molecular noise affects the emergence and robustness of circadian oscillations. Finally, we present a deterministic model for the mammalian circadian clock and use it to address the dynamical bases of physiological disorders of the sleep/wake cycle in humans.

Analysis of Biological Systems

Analysis of Biological Systems Book
Author : Corrado Priami,Melissa J Morine
Publisher : World Scientific
Release : 2015-01-29
ISBN : 1783266899
Language : En, Es, Fr & De

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Book Description :

Modeling is fast becoming fundamental to understanding the processes that define biological systems. High-throughput technologies are producing increasing quantities of data that require an ever-expanding toolset for their effective analysis and interpretation. Analysis of high-throughput data in the context of a molecular interaction network is particularly informative as it has the potential to reveal the most relevant network modules with respect to a phenotype or biological process of interest. Analysis of Biological Systems collects classical material on analysis, modeling and simulation, thereby acting as a unique point of reference. The joint application of statistical techniques to extract knowledge from big data and map it into mechanistic models is a current challenge of the field, and the reader will learn how to build and use models even if they have no computing or math background. An in-depth analysis of the currently available technologies, and a comparison between them, is also included. Unlike other reference books, this in-depth analysis is extended even to the field of language-based modeling. The overall result is an indispensable, self-contained and systematic approach to a rapidly expanding field of science. Contents:Algorithmic Systems BiologySetting the ContextSystems and ModelsStatic Modeling TechnologiesDynamic Modeling TechnologiesLanguage-based ModelingDynamic Modeling ProcessSimulationPerspectives and ConclusionsAppendix A: Basic MathAppendix B: Probability and StatisticsAppendix C: Semantics of Modeling Languages Readership: Graduate students in computer science, physics, mathematics or engineering or biology-related fields who want to better understand how to develop and use models of biological systems. Practitioners in systems biology who want to understand algorithmic modeling and algorithmic systems biology. Key Features:The book jointly deals with static (statistical) and dynamic (simulation) technologies making it a strong reference for who wants to approach real systems biology problemsThe content of the book is the result of more than ten years application of the material in university courses and to industrial-level problems in systems pharmacology and systems nutritionThere is no reference work available for the field of language-based modeling that is studied in depth in this bookKeywords:Modeling;Simulation;Network Analysis;Systems Biology;Systems Nutrition;Systems Pharmacology;Stochastic Models;Programming Biology;Multivariate Analysis

Computational Systems Biology

Computational Systems Biology Book
Author : Andres Kriete,Roland Eils
Publisher : Elsevier
Release : 2005-11-10
ISBN : 9780080459349
Language : En, Es, Fr & De

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Book Description :

Systems Biology is concerned with the quantitative study of complex biosystems at the molecular, cellular, tissue, and systems scales. Its focus is on the function of the system as a whole, rather than on individual parts. This exciting new arena applies mathematical modeling and engineering methods to the study of biological systems. This book is the first of its kind to focus on the newly emerging field of systems biology with an emphasis on computational approaches. The work covers new concepts, methods for information storage, mining and knowledge extraction, reverse engineering of gene and metabolic networks, as well as modelling and simulation of multi-cellular systems. Central themes include strategies for predicting biological properties and methods for elucidating structure-function relationships.

Theoretical Physics for Biological Systems

Theoretical Physics for Biological Systems Book
Author : Paola Lecca,Angela Re
Publisher : CRC Press
Release : 2019-01-30
ISBN : 135137432X
Language : En, Es, Fr & De

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Book Description :

Quantum physics provides the concepts and their mathematical formalization that lend themselves to describe important properties of biological networks topology, such as vulnerability to external stress and their dynamic response to changing physiological conditions. A theory of networks enhanced with mathematical concepts and tools of quantum physics opens a new area of biological physics, the one of systems biological physics.

College of Engineering University of Michigan Publications

College of Engineering  University of Michigan  Publications Book
Author : University of Michigan. College of Engineering
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Also contains brochures, directories, manuals, and programs from various College of Engineering student organizations such as the Society of Women Engineers and Tau Beta Pi.

Aerospace Medicine and Biology

Aerospace Medicine and Biology Book
Author : Anonim
Publisher : Unknown
Release : 1986
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Aerospace Medicine and Biology book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Dissertation Abstracts International

Dissertation Abstracts International Book
Author : Anonim
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Dissertation Abstracts International book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Ecology

Ecology Book
Author : Robert S. Leisner,Edward J. Kormondy
Publisher : WCB/McGraw-Hill
Release : 1971
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Ecology book written by Robert S. Leisner,Edward J. Kormondy, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Catalogs of Courses

Catalogs of Courses Book
Author : University of California, Berkeley
Publisher : Unknown
Release : 1982
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Includes general and summer catalogs issued between 1878/1879 and 1995/1997.

Workshop on stochastic modelling in biology

Workshop on stochastic modelling in biology Book
Author : Anonim
Publisher : Unknown
Release : 1990
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Workshop on stochastic modelling in biology book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The University of Michigan Bulletin

The University of Michigan Bulletin Book
Author : University of Michigan
Publisher : Unknown
Release : 2003
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Each number is the catalogue of a specific school or college of the University.

Annual Report

Annual Report Book
Author : European Science Foundation
Publisher : Unknown
Release : 1990
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Annual Report book written by European Science Foundation, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Towards a Theoretical Biology

Towards a Theoretical Biology Book
Author : Conrad Hal Waddington
Publisher : Unknown
Release : 1968
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Towards a Theoretical Biology book written by Conrad Hal Waddington, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Abstracts of Papers Presented to the American Mathematical Society

Abstracts of Papers Presented to the American Mathematical Society Book
Author : American Mathematical Society
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Abstracts of Papers Presented to the American Mathematical Society book written by American Mathematical Society, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Oxygen Transport to Tissue

Oxygen Transport to Tissue Book
Author : Haim I. Bicher,Duane F. Bruley
Publisher : Springer
Release : 1973-11-01
ISBN : 9780306390937
Language : En, Es, Fr & De

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Book Description :

It can honestly be said that the scope and magnitude of this meeting surpassed initial expectations with respect to the number and quality of the papers presented. Our group has grown since we last met in Dortmund in 1971. This is a good indication that a spiraling of our interests has taken place with the effects of the initial good work felt, not just in one corner of the globe, but in all four. With such a start, it was only appropriate that an international society was formed at the meeting to further coordinate our mutual undertaking. Henceforth it shall be known as the International Society of Oxygen Transport to Tissue. A final note of acknowledgement should be made to those who were in the supporting cast, not only in making the meeting in Charleston and Clemson a success, but also in the compiling of this book. Gratitude is due to Dr. Daniel H. Hunt for his efforts, the end product of which you have in your hands. Considerable service was rendered by Mr. Robert J. Adams, Mr. Buddy Bell and Mr. Nathan Kaufman during the symposium itself. Much typing, organizing and record keeping was done by our lovely secretaries, Laura B. Grove, Muff Graham and Kaye Y. Zook.

Mathematical Reviews

Mathematical Reviews Book
Author : Anonim
Publisher : Unknown
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Mathematical Reviews book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Annual Review of Plant Physiology

Annual Review of Plant Physiology Book
Author : Daniel Israel Arnon,L. R. Blinks,Alden Springer Crafts,Leonard Machlis
Publisher : Unknown
Release : 1979-06
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Annual Review of Plant Physiology book written by Daniel Israel Arnon,L. R. Blinks,Alden Springer Crafts,Leonard Machlis, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.