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Detection And Identification Of Designer Drugs

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Detection and Identification of Designer Drugs

Detection and Identification of Designer Drugs Book
Author : Brian F. Thomas
Publisher : Elsevier
Release : 2017-11
ISBN : 9780128117644
Language : En, Es, Fr & De

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Book Description :

Detection and Identification of Designer Drugs, a title in the Emerging Issues in Analytical Chemistry series, presents both an overview and a guide to techniques for anyone studying or engaging in designer drug analysis. Proliferation of the synthesis and use of designer drugs is a serious public health problem with social, economic and legal implications. Whether abuse is studied at the population level or the individual level, researchers need both background and highly detailed technical information on specific drugs and drug classes in order to combat the proliferation and highly damaging consequences of these substances. Author Brian F. Thomas provides a comprehensive discussion that emphasizes the potential threat to society, presents the ongoing challenges confronting the various laboratory approaches to detection and identification of new chemical entities and informs the development of improved analytical solutions for use in legislation, law enforcement and treatment. Summarizes the literature and evaluates the strengths and weaknesses of analytical methods for detecting and identifying designer drugs Offers authoritative information from author Brian F. Thomas, an expert with over 30 years of experience in the field Directs the reader to sources of further reading at the conclusion of each chapter Emphasizes the potential threat to society and presents ongoing challenges confronting various laboratory approaches to detection and identification of new chemical entities

Detection of Drug Misuse

Detection of Drug Misuse Book
Author : Kim Wolff
Publisher : Royal Society of Chemistry
Release : 2017-04-13
ISBN : 1782621571
Language : En, Es, Fr & De

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Book Description :

This book describes recent advances in biomarkers, instrumentation and analysis methodology for identifying drug misuse. It is aimed at healthcare professionals, academics and postgraduates.

Chromatographic Techniques in the Forensic Analysis of Designer Drugs

Chromatographic Techniques in the Forensic Analysis of Designer Drugs Book
Author : Teresa Kowalska,Mieczyslaw Sajewicz,Joseph Sherma
Publisher : CRC Press
Release : 2018-01-31
ISBN : 1315313162
Language : En, Es, Fr & De

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Book Description :

There is a dramatic rise of novel drug use due to the increased popularity of so-called designer drugs. These synthetic drugs can be illegal in some countries, but legal in others and novel compounds unknown to drug chemistry emerge monthly. This thoughtfully constructed edited reference presents the main chromatographic methodologies and strategies used to discover and analyze novel designer drugs contained in diverse biological materials. The methods are based on molecular characteristics of the drugs belonging to each individual class of compounds, so it will be clear how the current methods are adaptable to future new drugs that appear in the market.

Synthetic Cathinones

Synthetic Cathinones Book
Author : Jolanta B. Zawilska
Publisher : Springer
Release : 2018-04-16
ISBN : 3319787071
Language : En, Es, Fr & De

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Book Description :

Over the last decade, and particularly during the recent five years, a rapidly increasing number of novel psychoactive substance (NPSs), often marketed as “designer drugs”, “legal highs”, “herbal highs”, “research or intermediate chemicals” and “laboratory reagents”, has appeared on the drug market in an effort to bypass controlled substance legislation. NPSs encompass a wide range of different compounds and drug classes but had been dominated by synthetic cannabinomimetics and psychostimulatory synthetic cathinones, so-called β-keto amphetamines. Compounds from the later class were first detected in Europe in 2004, and since then 103 new cathinones have been identified and reported to the European Monitoring Centre for Drugs and Drug Addiction, with 57 during the last two years. Synthetic cathinones – novel addictive and stimulatory psychoactive substances is the first publication of this kind that provides readers with background on chemical structures, detection, prevalence and motivation of use of the very popular group of NPSs. This book also presents comprehensive overview of the mechanisms of action, pharmacological activity, and main metabolic pathways of synthetic cathinones, followed by a detailed discussion of the acute and chronic toxicity associated with the use of these substances. Written by international experts in the field, this multi-authored book is a valuable reference not only for scientists, clinicians and academics, but also for readers representing different professional background who are involved in educational-prophylactic activities directed to harm reduction of psychoactive compounds.

Chromatographic Techniques in the Forensic Analysis of Designer Drugs

Chromatographic Techniques in the Forensic Analysis of Designer Drugs Book
Author : Teresa Kowalska,Mieczyslaw Sajewicz,Joseph Sherma
Publisher : CRC Press
Release : 2018-01-31
ISBN : 1315313154
Language : En, Es, Fr & De

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Book Description :

There is a dramatic rise of novel drug use due to the increased popularity of so-called designer drugs. These synthetic drugs can be illegal in some countries, but legal in others and novel compounds unknown to drug chemistry emerge monthly. This thoughtfully constructed edited reference presents the main chromatographic methodologies and strategies used to discover and analyze novel designer drugs contained in diverse biological materials. The methods are based on molecular characteristics of the drugs belonging to each individual class of compounds, so it will be clear how the current methods are adaptable to future new drugs that appear in the market.

Encyclopedia of Forensic Sciences

Encyclopedia of Forensic Sciences Book
Author : Anonim
Publisher : Academic Press
Release : 2012-12-28
ISBN : 0123821665
Language : En, Es, Fr & De

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Book Description :

Forensic science includes all aspects of investigating a crime, including: chemistry, biology and physics, and also incorporates countless other specialties. Today, the service offered under the guise of "forensic science’ includes specialties from virtually all aspects of modern science, medicine, engineering, mathematics and technology. The Encyclopedia of Forensic Sciences, Second Edition is a reference source that will inform both the crime scene worker and the laboratory worker of each other’s protocols, procedures and limitations. Written by leading scientists in each area, every article is peer reviewed to establish clarity, accuracy, and comprehensiveness. As reflected in the specialties of its Editorial Board, the contents covers the core theories, methods and techniques employed by forensic scientists – and applications of these that are used in forensic analysis. This 4-volume set represents a 30% growth in articles from the first edition, with a particular increase in coverage of DNA and digital forensics Includes an international collection of contributors The second edition features a new 21-member editorial board, half of which are internationally based Includes over 300 articles, approximately 10pp on average Each article features a) suggested readings which point readers to additional sources for more information, b) a list of related Web sites, c) a 5-10 word glossary and definition paragraph, and d) cross-references to related articles in the encyclopedia Available online via SciVerse ScienceDirect. Please visit www.info.sciencedirect.com for more information This new edition continues the reputation of the first edition, which was awarded an Honorable Mention in the prestigious Dartmouth Medal competition for 2001. This award honors the creation of reference works of outstanding quality and significance, and is sponsored by the RUSA Committee of the American Library Association

Hair Analysis in Clinical and Forensic Toxicology

Hair Analysis in Clinical and Forensic Toxicology Book
Author : Pascal Kintz,Alberto Salomone,Marco Vincenti
Publisher : Academic Press
Release : 2015-06-25
ISBN : 0128017104
Language : En, Es, Fr & De

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Book Description :

Hair Analysis in Clinical and Forensic Toxicology is an essential reference for toxicologists working with, and researching, hair analysis. The text presents a review of the most up-to-date analytical methods in toxicological hair analysis, along with state-of-the-art developments in the areas of hair physiology, sampling, and pre-treatments, as well as discussions of fundamental issues, applications, and results interpretation. Topics addressed include the diagnosis of chronic excessive alcohol drinking by means of ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEE), the early detection of new psychoactive substances, including designer drugs, the development of novel approaches to screening tests based on mass spectrometry, and the detection of prenatal exposure to psychoactive substances from the analysis of newborn hair. Unites an international team of leading experts to provide an update on the cutting-edge advances in the toxicological analysis of hair Demonstrates toxicological techniques relating to a variety of scenarios and exposure types Ideal resource for the further study of the psychoactive substances, drug-facilitated crimes, ecotoxicology, analytical toxicology, occupational toxicology, toxicity testing, and forensic toxicology Includes detailed instructions for the collection, preparation, and handling of hair, and how to best interpret results

Critical Issues in Alcohol and Drugs of Abuse Testing

Critical Issues in Alcohol and Drugs of Abuse Testing Book
Author : Amitava Dasgupta
Publisher : Academic Press
Release : 2019-01-10
ISBN : 0128156082
Language : En, Es, Fr & De

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Book Description :

Critical Issues in Alcohol and Drugs of Abuse Testing, Second Edition, addresses the general principles and technological advances for measuring drugs and alcohol, along with the pitfalls of drugs of abuse testing. Many designer drugs, for example, are not routinely tested in drugs of abuse panels and may go undetected in a drug test. This updated edition is a must-have for clinical pathologists, toxicologists, clinicians, and medical review officers and regulators, bridging the gap between technical and clinical information. Topics of note include the monitoring of pain management drugs, bath salts, spices (synthetic marijuana), designer drugs and date rape drugs, and more. Serves as a ready resource of information for alcohol and drug testing Ideal resource for making decisions related to the monitoring and interpretation of results Includes concise content for clinical laboratory scientists, toxicologists and clinicians

Novel Psychoactive Substances

Novel Psychoactive Substances Book
Author : Paul Dargan,David Wood
Publisher : Academic Press
Release : 2013-08-06
ISBN : 0124159117
Language : En, Es, Fr & De

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Book Description :

Novel Psychoactive Substances: Classification, Pharmacology and Toxicology provides readers with background on the classification, detection, supply and availability of novel psychoactive substances, otherwise known as "legal highs." This book also covers individual classes of novel psychoactive substances that have recently emerged onto the recreational drug scene and provides an overview of the pharmacology of the substance followed by a discussion of the acute and chronic harm or toxicity associated with the substance. Written by international experts in the field, this multi-authored book is a valuable reference for scientists, clinicians, academics, and regulatory and law enforcement professionals. Includes chapters written by international experts in the field. Provides a comprehensive look at the classification, detection, availability and supply of novel psychoactive substances, in addition to the pharmacology and toxicology associated with the substance. Offers a single source for all interested parties working in this area, including scientists, academics, clinicians, law enforcement and regulatory agencies. Provides a full treatment of novel psychoactive substances that have recently emerged onto the recreational drug scene including mephedrone and the synthetic cannabinoid receptors in ‘spice’ / ‘K2’.

Interpretation of MS MS Mass Spectra of Drugs and Pesticides

Interpretation of MS MS Mass Spectra of Drugs and Pesticides Book
Author : Wilfried M. A. Niessen,Ricardo A. Correa C.
Publisher : John Wiley & Sons
Release : 2017-01-03
ISBN : 111929424X
Language : En, Es, Fr & De

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Book Description :

Provides comprehensive coverage of the interpretation of LC–MS–MS mass spectra of 1300 drugs and pesticides Provides a general discussion on the fragmentation of even-electron ions (protonated and deprotonated molecules) in both positive-ion and negative-ion modes This is the reference book for the interpretation of MS–MS mass spectra of small organic molecules Covers related therapeutic classes of compounds such as drugs for cardiovascular diseases, psychotropic compounds, drugs of abuse and designer drugs, antimicrobials, among many others Covers general fragmentation rule as well as specific fragmentation pathways for many chemical functional groups Gives an introduction to MS technology, mass spectral terminology, information contained in mass spectra, and to the identification strategies used for different types of unknowns

Essentials of Autopsy Practice

Essentials of Autopsy Practice Book
Author : Guy N. Rutty
Publisher : Springer
Release : 2017-02-14
ISBN : 3319469975
Language : En, Es, Fr & De

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Book Description :

This book covers topical subjects within the field of death investigation, where changes in practice have recently occurred. As the area of dating of wounds has changed since the subject was addressed in a previous volume, this subject is revisited for the first time. The remaining subjects covered in this volume embrace the multi-disciplinary approach required for death investigation, and address advances in the field of forensic radiology imaging, pathology, and toxicology. There is also a chapter on cardiopulmonary resuscitation which explains clinical processes and procedures that may occur to an individual immediately before death that may have a bearing on the subsequent autopsy findings. Essentials of Autopsy Practice: Reviews, Updates and Advances is an educational and practical resource aimed at trainees and consultants, generalists and specialists, and the new multi-disciplinary team alike.

Addictions

Addictions Book
Author : Barbara S. McCrady,Elizabeth E. Epstein
Publisher : Oxford University Press
Release : 2013-10-03
ISBN : 0199753660
Language : En, Es, Fr & De

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Book Description :

Addictions: A Comprehensive Guidebook, Second Edition, features a roster of senior scientists covering the latest findings in the study of alcohol and other drug use, abuse, and dependence.

Novel Psychoactive Drugs The Saga Continues

Novel Psychoactive Drugs   The Saga Continues    Book
Author : Aviv M Weinstein,Liana Fattore
Publisher : Frontiers Media SA
Release : 2021-04-05
ISBN : 2889666611
Language : En, Es, Fr & De

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Book Description :

Download Novel Psychoactive Drugs The Saga Continues book written by Aviv M Weinstein,Liana Fattore, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Alcohol Drugs Genes and the Clinical Laboratory

Alcohol  Drugs  Genes and the Clinical Laboratory Book
Author : Amitava Dasgupta
Publisher : Academic Press
Release : 2016-10-17
ISBN : 012809334X
Language : En, Es, Fr & De

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Book Description :

Alcohol, Drugs, Genes and the Clinical Laboratory provides an overview and quick reference to genetic relationships and clinical laboratory information related to the serious public health issue of alcohol and drug abuse. Written in a clear and concise manner, this book discusses the necessary information for health and safety professionals working in public health to learn about complex issues quickly to better help their patients, employees, and others affected by alcohol and drug abuse. Alcohol, Drugs, Genes and the Clinical Laboratory covers the important aspects of drugs and alcohol abuse including genetic aspects along with laboratory methods for analysis of alcohol and abused drugs with emphasis on false positive test results. The book is helpful to healthcare professionals, such as pathologists who oversee alcohol and drug testing, emergency room physicians, family practice physicians who are first healthcare professionals who identify patients susceptible to drug and alcohol abuse, and psychiatrists involved with drug and alcohol rehabilitation programs. It will also be useful to safety professionals who have to assess individuals for workplace responsibilities, ranging from police and recruitment to occupational safety and occupational medicine and public health officials. Features accessible language for healthcare and safety professionals who are not experts in laboratory procedures Provides examples from clinical and everyday situations Explains how to interpret laboratory results and the latest genetic factors regarding drug and alcohol abuse

Forensic Toxicology

Forensic Toxicology Book
Author : Max M. Houck
Publisher : Academic Press
Release : 2018-01-02
ISBN : 0128008180
Language : En, Es, Fr & De

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Book Description :

Forensic Toxicology, the latest release in the Advanced Forensic Science Series that grew out of recommendations from the 2009 NAS Report, Strengthening Forensic Science: A Path Forward will serve as a graduate level text for those studying and teaching forensic toxicology. It is also an excellent reference for the forensic practitioner’s library or for use in their casework. Coverage includes a wide variety of methods used, along with pharmacology and drugs and professional issues they may encounter. Edited by a world-renowned, leading forensic expert, this updated edition is a long overdue solution for the forensic science community. Provides basic principles of forensic science and an overview of forensic toxicology Contains information on a wide variety of methods Covers pharmacology and drugs, matrices and interpretation Includes a section on professional issues, such as crime scene to court, lab reports, health and safety, post-mortem and drug facilitated crimes Incorporates effective pedagogy, key terms, review questions, discussion questions and additional reading suggestions

Chemical Analysis of Non antimicrobial Veterinary Drug Residues in Food

Chemical Analysis of Non antimicrobial Veterinary Drug Residues in Food Book
Author : Jack F. Kay,James D. MacNeil,Jian Wang
Publisher : John Wiley & Sons
Release : 2016-11-21
ISBN : 1119325919
Language : En, Es, Fr & De

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Book Description :

Provides a single-source reference for readers interested in the development of analytical methods for analyzing non-antimicrobial veterinary drug residues in food Provides a comprehensive set of information in the area of consumer food safety and international trade Covers general issues related to analytical quality control and quality assurance, measurement uncertainty, screening and confirmatory methods Details many techniques including nanotechnology and aptamer based assays covering current and potential applications for non-antimicrobial veterinary drugs Provides guidance for analysis of banned drugs including natural and synthetic steroids, Resorcylic acid lactones, and Beta-agonists

Interpol s Forensic Science Review

Interpol s Forensic Science Review Book
Author : Niamh Nic Daeid,Max Houck
Publisher : CRC Press
Release : 2017-08-09
ISBN : 1439826595
Language : En, Es, Fr & De

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Book Description :

Every three years, worldwide forensics experts gather at the Interpol Forensic Science Symposium to exchange ideas and discuss scientific advances in the field of forensic science and criminal justice. Drawn from contributions made at the latest gathering in Lyon, France, Interpol's Forensic Science Review is a one-source reference providing a comp

Adelson s The Pathology of Homicide A Guide for Forensic Pathologists and Homicide Investigators 2nd Edition

Adelson s The Pathology of Homicide  A Guide for Forensic Pathologists and Homicide Investigators  2nd Edition  Book
Author : James R. Gill
Publisher : Charles C Thomas Publisher
Release : 2022-10-05
ISBN : 0398093911
Language : En, Es, Fr & De

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Book Description :

Dr. Lester Adelson's original The Pathology of Homicide has been described as a "superb textbook" and "without doubt…the best written book of its type in the English language" by Dr. Charles Hirsch. This new, revised edition preserves Dr. Adelson's eloquent and articulate voice, while bringing the subject matter up to date. Since the first edition was published in 1974, Dr. Adelson’s book was a treasured text among many forensic pathologists. The “aging” of the book, however, made it less appealing to the new generation of forensic pathologists, and Dr. Adelson’s important contribution to forensic pathology was at risk of being lost. Although much has changed in forensic pathology in the ensuing nearly fifty years since it was first written, much also has stayed the same. In this new edition, the author, Dr. James Gill—Chief Medical Examiner of the State of Connecticut and past president of the National Association of Medical Examiners—preserves the voice, vision, and wisdom of Dr. Adelson while updating the forensic pathology material. The author has included nearly 700 all new color images. In addition, the references have been updated with over 4,400 citations. Six new chapters and sections have been added, including death certification, elder abuse, pediatric head injury, drugs of misuse, histopathology, and bereavement. Other updates are included on DNA technology, CT scans, and novel drugs. Although primarily concerned with homicides, there is the need to be able to recognize natural, accidental, and suicidal deaths; therefore, these topics are interspersed in the text to give the appropriate context. This book will help the reader understand the details of injuries and how a person was injured, why they died, and how these injuries, perhaps at first blush seemingly insignificant, can shed new light on a death investigation. It is the author’s hope to get this book to the next generation of forensic pathologists.

Metabolism of Drugs and Other Xenobiotics

Metabolism of Drugs and Other Xenobiotics Book
Author : Pavel Anzenbacher,Ulrich M. Zanger
Publisher : John Wiley & Sons
Release : 2012-02-23
ISBN : 3527646329
Language : En, Es, Fr & De

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Book Description :

A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviews the main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the three main classes of xenobiotics: drugs, natural products, environmental pollutants. The part on drugs includes more than 300 substances from five major therapeutic groups (central nervous system, cardiovascular system, cancer, infection, and pain) as well as most drugs of abuse including nicotine, alcohol and "designer" drugs. Selected, well-documented case studies from the most important xenobiotics classes illustrate general principles of metabolism, making this equally useful for teaching courses on pharmacology, drug metabolism or molecular toxicology. Of particular interest, and unique to this volume is the inclusion of a wide range of additional xenobiotic compounds, including food supplements, herbal preparations, and agrochemicals.

Neuropathology of Drug Addictions and Substance Misuse Volume 3

Neuropathology of Drug Addictions and Substance Misuse Volume 3 Book
Author : Victor R. Preedy
Publisher : Academic Press
Release : 2016-04-25
ISBN : 0128006773
Language : En, Es, Fr & De

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Book Description :

Neuropathology of Drug Addictions and Substance Misuse, Volume 3: General Processes and Mechanisms, Prescription Medications, Caffeine and Areca, Polydrug Misuse, Emerging Addictions and Non-Drug Addictions is the third of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. Each volume serves to update the reader’s knowledge on the broader field of addiction as well as to deepen understanding of specific addictive substances. Volume 3 addresses prescription medications, caffeine, polydrug misuse, and non-drug addictions. Each section provides data on the general, molecular, cellular, structural, and functional neurological aspects of a given substance, with a focus on the adverse consequences of addictions. Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention and treatment. However, marshalling data on the complex relationships between addictions is difficult due to the myriad of material and substances. Offers a modern approach to understanding the pathology of substances of abuse, offering an evidence-based ethos for understanding the neurology of addictions Fills an existing gap in the literature by serving as a “one-stop-shopping synopsis of everything to do with the neuropathology of drugs of addiction and substance misuse Includes in each chapter: list of abbreviations, abstract, introduction, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, full references Offers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and from the genome to whole body