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Designing And Conducting Translational Research

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Translational and Experimental Clinical Research

Translational and Experimental Clinical Research Book
Author : Daniel P. Schuster,William J. Powers (MD.)
Publisher : Lippincott Williams & Wilkins
Release : 2005
ISBN : 9780781755658
Language : En, Es, Fr & De

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Book Description :

This volume is a comprehensive textbook for investigators entering the rapidly growing field of translational and experimental clinical research. The book offers detailed guidelines for designing and conducting a study and analyzing and reporting results and discusses key ethical and regulatory issues. Chapters address specific types of studies such as clinical experiments in small numbers of patients, pharmacokinetics and pharmacodynamics, and gene therapy and pharmacogenomic studies. A major section describes modern techniques of translational clinical research, including gene expression, identifying mutations and polymorphisms, cloning, transcriptional profiling, proteomics, cell and tissue imaging, tissue banking, evaluating substrate metabolism, and in vivo imaging.

Clinical and Translational Science

Clinical and Translational Science Book
Author : David Robertson,Gordon H. Williams
Publisher : Academic Press
Release : 2009-03-02
ISBN : 9780080920191
Language : En, Es, Fr & De

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Book Description :

Clinical or translational science is the field of study devoted to investigating human health and disease, interventions and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. New molecular tools and diagnostic technologies based on clinical and translational research have lead to a better understanding of human disease and the application of new therapeutics for enhanced health. Clinical and Translational Science is designed as the most authoritative and modern resource for the broad range of investigators in various medical specialties taking on the challenge of clinical research. Prepared with an international perspective, this resource begins with experimental design and investigative tools to set the scene for readers. It then moves on to human genetics and pharmacology with a focus on statistics, epidemiology, genomic information, drug discovery and development, and clinical trials. Finally, it turns to legal, social, and ethical issues of clinical research concluding with a discussion of future prospects to provide readers with a comprehensive view of the this developing area of science. Clinical research is one of the fastest growing fields in private practice and academic medicine with practical biological, physiological, cellular, and therapeutic applications Contributions from international leaders provide insight into background and future understanding for clinical and translational science Provides the structure for complete instruction and guidance on the subject from fundamental principles, approaches and infrastructure to human genetics, human pharmacology, research in special populations, the societal context of human research, and the future of human research

Journal of the National Cancer Institute

Journal of the National Cancer Institute Book
Author : Anonim
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Neuroepidemiology

Neuroepidemiology Book
Author : Lorene M. Nelson
Publisher : Oxford University Press
Release : 2004
ISBN : 019513379X
Language : En, Es, Fr & De

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Book Description :

This fine text provides a comprehensive overview of methods for epidemiologic and clinical research on neurological disorders. The book focuses on classic principles of study design in epidemiologic research, strategies for avoiding study biases, methods for conducting clinical trials and prognostic studies, and principles of evidence-based medicine in neurology. The text gives neurologists, epidemiologists, and their students the foundation for conducting rigorous epidemiologic and clinical research on neurologic disorders.

Fundamentals of Evidence Based Health Care and Translational Science

Fundamentals of Evidence Based Health Care and Translational Science Book
Author : Francesco Chiappelli
Publisher : Springer Science & Business Media
Release : 2014-03-18
ISBN : 3642418570
Language : En, Es, Fr & De

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Book Description :

Comparative effectiveness research – the conduct and synthesis of systematic research in order to compare the benefits and harms of alternative treatment options – is of critical importance in enabling informed health care decisions to be made. This user-friendly, practical handbook examines in depth how best to perform such comparative effectiveness research. A wide range of topics and methods are discussed, including research synthesis, sampling analysis, assessment of evidence design, systematic evaluation of statistical analysis, and meta-analysis. The discussion extends well beyond the fundamentals by encompassing “complex” systematic reviews, “cumulative” meta-analyses, and logic-based versus utility-based decision making. Health care providers, researchers, instructors, and students will all find this to be an invaluable reference on the compelling current issues and important analytical tools in comparative effectiveness research.

Wiley Encyclopedia of Clinical Trials

Wiley Encyclopedia of Clinical Trials Book
Author : Lisa Marie Sullivan,Joseph Massaro
Publisher : Wiley-Interscience
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Here you'll find more than 500 entries from the world's leading experts in the field on the basic concepts, methodologies, and applications in clinical trials. The range of topics includes: basic statistical concepts, design and analysis of clinical trials, ethics, regulatory issues, and methodologies for clinical data management and analysis

American Journal of Respiratory and Critical Care Medicine

American Journal of Respiratory and Critical Care Medicine Book
Author : Anonim
Publisher : Unknown
Release : 2010
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Leininger s Transcultural Nursing Concepts Theories Research Practice Fourth Edition

Leininger s Transcultural Nursing  Concepts  Theories  Research   Practice  Fourth Edition Book
Author : Marilyn R. McFarland,Hiba B. Wehbe-Alamah
Publisher : McGraw Hill Professional
Release : 2018-04-06
ISBN : 0071841121
Language : En, Es, Fr & De

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Book Description :

The Most Comprehensive Presentation of Transcultural Nursing Concepts Featuring the Newly Revised Sunrise Enabler! Leininger’s Transcultural Nursing: Concepts,Theories, Research & Practices, Fourth Edition offers theoretical and practical guidance on the provision of client-focused care by integrating cultural values, beliefs, and lifeways into an individualized plan of care. Transcultural nursing is a vital, holistic approach that allows nurses and other healthcare providers to provide culturally congruent care for individuals, families, groups, and organizations within a context that is meaningful, beneficial, and inclusive of their healthcare values, beliefs, practices, traditions, communication styles, diverse roles,dietary preferences, and more. The text presents a global comparative perspective about Western and non-Western cultures and examines the future direction of transcultural nursing with insights into rural and urban cultures in the United States including the culture care of homeless mothers and children. The book chapters cover such topics as transcultural nursing, research, and healthcare in Kenya, Southeast Asia, Haiti, Syria, and Taiwan as well as translational research, globalization,conflict resolution, mental health considerations, Ayurvedic medicine, genetics and genomics in healthcare, integration of care and caring, and an overview of transcultural history, concepts, and principles. Leininger’s Transcultural Nursing: Concepts,Theories, Research, and Practices was edited by two experts in the field and uses Leininger's Theory of Culture Care Diversity and Universality and the Ethnonursing Research Method to provide a useful blend of theory and practical clinical information.

Mixed Methods Research

Mixed Methods Research Book
Author : Vicki L. Plano Clark,Nataliya V. Ivankova
Publisher : SAGE Publications
Release : 2015-09-23
ISBN : 1483347133
Language : En, Es, Fr & De

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Book Description :

Mixed Methods Research: A Guide to the Field by Vicki L. Plano Clark and Nataliya V. Ivankova is a practical book that introduces a unique socio-ecological framework for understanding the field of mixed methods research and its different perspectives. Based on the framework, it addresses basic questions including: What is the mixed methods research process? How is mixed methods research defined? Why is it used? What designs are available? How does mixed methods research intersect with other research approaches? What is mixed methods research quality? How is mixed methods shaped by personal, interpersonal, and social contexts? By focusing on the topics, perspectives, and debates occurring in the field of mixed methods research, the book helps students, scholars, and researchers identify, understand, and participate in these conversations to inform their own research practice. Mixed Methods Research is Volume 3 in the SAGE Mixed Methods Research Series.

Conducting Clinical Research

Conducting Clinical Research Book
Author : Judy Stone
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

In Conducting Clinical Research: A Practical Guide for Physicians, Nurses, Study Coordinators, and Investigators you will discover how to Attract drug companies to your site Land a study on good terms Recruit patient volunteers—and keep them happy! Implement easy strategies for coordinating studies Organize your clinical trial activities Demystify regulatory requirements Conducting Clinical Research is a practical, user-friendly how-to manual for medical professionals—physicians, nurses, study coordinators and investigators—who are interested in learning what it takes to carry out clinical trials. Everything is covered—from how drugs are developed to how to attract drug companies to a site, land a study, recruit volunteers, coordinate studies, organize clinical trial activities, and navigate regulatory requirements. Even ethical and social issues are discussed. Comprehensive appendices offer essential background, resources, sample forms and worksheets, and information about careers and training programs. The book was a Ben Franklin Awards 2007 Finalist, and a 2007 Finalist in ForeWord Magazine's reference category for professional/technical books.

JAMA

JAMA Book
Author : Anonim
Publisher : Unknown
Release : 2003
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download JAMA book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Mixed Methods Applications in Action Research

Mixed Methods Applications in Action Research Book
Author : Nataliya V. Ivankova
Publisher : SAGE Publications
Release : 2014-09-25
ISBN : 1483322122
Language : En, Es, Fr & De

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Book Description :

This first-of-its-kind book provides readers with the information they need to design and conduct a mixed methods action research (MMAR) study in a practical and pragmatic manner. Using a multidisciplinary focus, the author provides a scholarly and applied orientation to meet the varied epistemological and professional needs of scholar practitioners. The book is applicable to broad audiences with different levels of research skills, including students learning how to conduct research in practical settings, practitioners faced with the need to address pertinent issues in their professional practices, community leaders seeking to inform policy changes, and college faculty who teach research methods and conduct funded research in collaboration with practitioner-researchers and community stakeholders. A wide variety of pedagogical features make it appropriate for use as an instructional text aimed at developing skills in designing, conducting, implementing, and reporting an action research study that integrates mixed methods.

Intervention Research and Evidence Based Quality Improvement Second Edition

Intervention Research and Evidence Based Quality Improvement  Second Edition Book
Author : Bernadette Mazurek Melnyk, PhD, RN, APRN-CNP, FAANP, FNAP, FAAN,Dianne Morrison-Beedy, PhD, RN, WHNP, FNAP, FAANP, FAAN
Publisher : Springer Publishing Company
Release : 2018-08-28
ISBN : 0826155715
Language : En, Es, Fr & De

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Book Description :

First Edition received 2012 First Place AJN Book of the Year Award in Nursing Research! “This is a resource for success and should be a part of any researcher's library." --Doody's Medical Reviews (Praise for the First Edition) Written for researchers, clinicians and doctoral students, the newly revised edition of this comprehensive reference continues to deliver the essentials of intervention research with added content on evidence-based quality improvement, a must for improving healthcare quality, safety and population health outcomes. Although typically it takes years for research-based interventions to make their way to real world clinical settings, this “prolonged time for translation” frustrates researchers and their interprofessional teams. This second edition now delves even deeper into key strategies for rapidly moving research-based interventions into real world settings in the form of evidence-based quality improvement as well as the challenges of working in an increasingly diverse professional research environment. Intervention Research and Evidence-Based Quality Improvement, Second Edition begins at the pilot study phase for intervention research and highlights every step of the way through to full-scale randomized controlled trials. Written in user-friendly format, content covers designing, conducting, analyzing, and funding intervention studies that improve healthcare quality and people’s health outcomes. Chapters cover writing grant applications and show examples of actual applications that have been funded by NIH and other organizations. These real-life samples are available online, alongside additional progress reports and final reports. Real-world examples of evidence-based quality improvement projects that have improved outcomes also are highlighted in this second edition. New to the Second Edition: Describes evidence-based quality improvement and specific steps in conducting EBQI projects, which are essential for enhancing healthcare quality, safety and costs along with enhancing population health outcomes. Emphasizes the importance of interprofessional teams Focuses on using research-based interventions in real-world settings Six new chapters o Generating Versus Using Evidence to Guide Best Practice o Setting the Stage for Intervention Research and Evidence-based Quality Improvement o Evidence-based Quality Improvement o Translational Research: Why and How o Factors Influencing Successful Uptake of Evidence-Based Interventions in Clinical Practice o Using Social Media to Enhance Uptake of Research-Based Interventions into Real World Clinical Settings Key Features: Provides a practical, comprehensive resource for designing, conducting, analyzing, and funding intervention studies Outlines the specific steps in designing, conducting and evaluating outcomes of evidence-based quality improvement projects Includes examples of funding research grants, progress reports, and final reports Serves as a core text for students in doctoral nursing and other health sciences programs

Cancer Research

Cancer Research Book
Author : Anonim
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Journal of Health Population and Nutrition

Journal of Health  Population  and Nutrition Book
Author : Anonim
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Journal of Health Population and Nutrition book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Research Report

Research Report Book
Author : Anonim
Publisher : Unknown
Release : 1999
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Scholarships fellowships and loans ba guide to education related financial aid programs for students and professionals

Scholarships  fellowships and loans   ba guide to education related financial aid programs for students and professionals Book
Author : Anonim
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Scholarships fellowships and loans ba guide to education related financial aid programs for students and professionals book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

APS Observer

APS Observer Book
Author : Anonim
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download APS Observer book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Conducting Science based Psychology Research in Schools

Conducting Science based Psychology Research in Schools Book
Author : Lisa M. Dinella
Publisher : Amer Psychological Assn
Release : 2009
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

"What are the common pitfalls experienced by school researchers, and how can those pitfalls be avoided? This edited volume draws on the collective expertise of both established and emerging names in the field, providing an unparalleled resource for those interested in conducting psychological research within school settings. First and foremost, the contributors offer a framework for conceptualizing rigorous research collaboratively with schools, instead of on or in them, by emphasizing the participation of administrators, teachers, and parents. With detailed information on how to build and maintain research programs and avoid common problems, this volume includes insights from both researchers and the education professionals with whom they collaborate. Organized to reflect the research process from beginning to end, the chapters examine first how to initiate and nurture relationships with school stakeholders, move next to improving research design and methodology, and conclude with how to best disseminate research findings to scholars, practitioners, and study participants. Conducting Science-Based Psychology Research in Schools is an essential tool for courses on research methods and school-based research in fields ranging from psychology to education, social work, and family and human development"--Jacket. (PsycINFO Database Record (c) 2009 APA, all rights reserved).