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Designing And Conducting Research In Translational Medicine

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Translational and Experimental Clinical Research

Translational and Experimental Clinical Research Book
Author : Daniel P. Schuster,William J. Powers (MD.)
Publisher : Lippincott Williams & Wilkins
Release : 2005
ISBN : 9780781755658
Language : En, Es, Fr & De

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Book Description :

This volume is a comprehensive textbook for investigators entering the rapidly growing field of translational and experimental clinical research. The book offers detailed guidelines for designing and conducting a study and analyzing and reporting results and discusses key ethical and regulatory issues. Chapters address specific types of studies such as clinical experiments in small numbers of patients, pharmacokinetics and pharmacodynamics, and gene therapy and pharmacogenomic studies. A major section describes modern techniques of translational clinical research, including gene expression, identifying mutations and polymorphisms, cloning, transcriptional profiling, proteomics, cell and tissue imaging, tissue banking, evaluating substrate metabolism, and in vivo imaging.

Evaluating and Conducting Research in Audiology

Evaluating and Conducting Research in Audiology Book
Author : Vinaya Manchaiah, Eldré Beukes, Ross J. Roeser
Publisher : Plural Publishing
Release : 2021-02-04
ISBN : 1635502012
Language : En, Es, Fr & De

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Book Description :

Evaluating and Conducting Research in Audiology is the first research methods textbook that is specific to the field of audiology and designed to serve as an academic textbook for audiology graduate students. This text can also be accessible for audiology practitioners who are interested in clinical and applied research. The comprehensive coverage includes materials for multiple courses within audiology degree programs, including research methods, analysis of professional literature, evidence-based practice, and capstone research projects. Classroom tested, and written by authors who have extensive backgrounds in publishing and editing, this text provides knowledge that is required in evaluating, conducting, and disseminating research. The book is separated into three sections: (a) research methods; (b) evidence-based practice; and (c) conducting and disseminating research. Together, these sections provide a detailed coverage of the research methods that are relevant to conducting research, particularly in the field of Audiology. Key Features: * Learning outcomes at the beginning of each chapter * End of chapter reviews including key points and study questions * Audiology-specific examples, research methods, and study designs * “Golden Nugget” boxes throughout the book containing valuable information related to the critical concepts * In-depth discussion of qualitative research methods, survey research methods, and systematic reviews to motivate students and early career researchers to consider these methodologies in their research

Translational Medicine

Translational Medicine Book
Author : James Mittra,Christopher-Paul Milne
Publisher : CRC Press
Release : 2016-04-19
ISBN : 9814364843
Language : En, Es, Fr & De

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Book Description :

This book brings together a range of academic, industry and practitioner perspectives on translational medicine (TM). It enhances conceptual and practical understanding of the emergence and progress of the field and its potential impact on basic research, therapeutic development, and institutional infrastructure. In recognition of the various implications TM has for public health policy and commercial innovation, the book addresses the major systemic aspects of the field. The contributors explore the dynamic interactions and key challenges in translating new science into viable therapies for the clinic, which includes recognizing the importance of social, commercial, and regulatory environments in addition to good science.

Pharmaceutical Medicine and Translational Clinical Research

Pharmaceutical Medicine and Translational Clinical Research Book
Author : Divya Vohora,Gursharan Singh
Publisher : Academic Press
Release : 2017-11-14
ISBN : 0128020989
Language : En, Es, Fr & De

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Book Description :

Pharmaceutical Medicine and Translational Clinical Research covers clinical testing of medicines and the translation of pharmaceutical drug research into new medicines, also focusing on the need to understand the safety profile of medicine and the benefit-risk balance. Pharmacoeconomics and the social impact of healthcare on patients and public health are also featured. It is written in a clear and straightforward manner to enable rapid review and assimilation of complex information and contains reader-friendly features. As a greater understanding of these aspects is critical for students in the areas of pharmaceutical medicine, clinical research, pharmacology and pharmacy, as well as professionals working in the pharmaceutical industry, this book is an ideal resource. Includes detailed coverage of current trends and key topics in pharmaceutical medicine, including biosimilars, biobetters, super generics, and Provides a comprehensive look at current and important aspects of the science and regulation of drug and biologics discovery

Designing and Conducting Gender Sex and Health Research

Designing and Conducting Gender  Sex  and Health Research Book
Author : John L. Oliffe,Lorraine Greaves
Publisher : SAGE
Release : 2011-04-18
ISBN : 1452236550
Language : En, Es, Fr & De

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Book Description :

This book provides the first resource dedicated to critically examining gender and sex in study designs, methods, and analysis in health research. In order to produce ethical, accurate, and effective research findings it is vital to integrate both sex (biological characteristics) and gender (socially constructed factors) into any health study. This book draws attention to some of the methodological complexities in this enterprise and offers ways to thoughtfully address these by drawing on empirical examples across a range of topics and disciplines.

How Translational Medicine Is Progressively Redefining Healthcare

How Translational Medicine Is Progressively Redefining Healthcare Book
Author : Fritz Dufour, MBA, DESS
Publisher : Fritz Dufour
Release : 2017-12-19
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The preliminary idea behind translational medicine, conducting biological research to treat diseases, is not a new concept. But, scientists have been serious about placing the patient at all levels of the research process – right at the basic science level phase and all the way to the bedside – since only the 1990s. Today, translational research is a scientific field, although multidisciplinary. That innovation stemmed from the discoveries of new diseases and new technologies that allow healthcare professionals to have new perspectives on how to better and more efficiently treat patients. Translational medicine is viable, and it has already proved itself in many areas. Normally, every great discovery or innovation comes with both rewards and challenges, and continuous improvement is what keeps it alive. Translational research, an innovative concept, is not impervious to that rule. This paper examines the antecedents of translational medicine and how it came about. It considers the importance of incorporating basic science, applied science or clinical research, and the patient at every turn of the processes by analyzing the importance of translational research and its direct applications. On the other hand, this paper considers the challenges faced by translational medicine in an age where healthcare costs are skyrocketing, and suggests what can be done to circumvent the downsides. Finally, because the field is relatively new and promising, the discussion that follows also considers the outlook for translational medicine, and how important it is for scientists – artificial intelligence experts, computer, or bioengineers, healthcare professionals and healthcare management professionals – to lay right now the groundwork for future generations.

Mixed Methods Applications in Action Research

Mixed Methods Applications in Action Research Book
Author : Nataliya V. Ivankova
Publisher : SAGE Publications
Release : 2014-09-25
ISBN : 1483322122
Language : En, Es, Fr & De

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Book Description :

This first-of-its-kind book provides readers with the information they need to design and conduct a mixed methods action research (MMAR) study in a practical and pragmatic manner. Using a multidisciplinary focus, the author provides a scholarly and applied orientation to meet the varied epistemological and professional needs of scholar practitioners. The book is applicable to broad audiences with different levels of research skills, including students learning how to conduct research in practical settings, practitioners faced with the need to address pertinent issues in their professional practices, community leaders seeking to inform policy changes, and college faculty who teach research methods and conduct funded research in collaboration with practitioner-researchers and community stakeholders. A wide variety of pedagogical features make it appropriate for use as an instructional text aimed at developing skills in designing, conducting, implementing, and reporting an action research study that integrates mixed methods.

Conducting Clinical Research

Conducting Clinical Research Book
Author : Judy Stone
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

In Conducting Clinical Research: A Practical Guide for Physicians, Nurses, Study Coordinators, and Investigators you will discover how to Attract drug companies to your site Land a study on good terms Recruit patient volunteers—and keep them happy! Implement easy strategies for coordinating studies Organize your clinical trial activities Demystify regulatory requirements Conducting Clinical Research is a practical, user-friendly how-to manual for medical professionals—physicians, nurses, study coordinators and investigators—who are interested in learning what it takes to carry out clinical trials. Everything is covered—from how drugs are developed to how to attract drug companies to a site, land a study, recruit volunteers, coordinate studies, organize clinical trial activities, and navigate regulatory requirements. Even ethical and social issues are discussed. Comprehensive appendices offer essential background, resources, sample forms and worksheets, and information about careers and training programs. The book was a Ben Franklin Awards 2007 Finalist, and a 2007 Finalist in ForeWord Magazine's reference category for professional/technical books.

Neuroepidemiology

Neuroepidemiology Book
Author : Lorene M. Nelson,Caroline M. Tanner,Stephen Van Den Eeden,Valerie M. McGuire
Publisher : Oxford University Press
Release : 2003-11-27
ISBN : 9780199748877
Language : En, Es, Fr & De

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Book Description :

Neuroepidemiology is the epidemiologic study of neurological conditions. This fine text provides a comprehensive and accessible overview of research methods for conducting epidemiologic and clinical research on these conditions. It is aimed at neurologists, epidemiologists and public health professionals, as well as students of these disciplines. The book has three parts, each emphasizing the unique aspects of studying neurologic disorders. The first focuses on classic principles of epidemiologic and clinical research, including study design, sources of study bias, and methods for assessing the role of environmental and genetic factors in neurologic disorders. The second part covers each of the major neurologic disorders, with an emphasis of the methodologic aspects of studying these disorders and discussion of future research directions. The third part is devoted to clinical and translational research methods, including the design and conduct of clinical trials and prognostic studies, as well as the principles of health services research and evidence-based medicine. This textbook will give neurologists, epidemiologists, and their students the foundation for conducting rigorous epidemiologic and clinical research on neurologic disorders.

Clinical Trials in Neurology

Clinical Trials in Neurology Book
Author : Bernard Ravina,Jeffrey Cummings,Michael McDermott,R. Michael Poole
Publisher : Cambridge University Press
Release : 2012-04-12
ISBN : 1107376572
Language : En, Es, Fr & De

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Book Description :

Translating laboratory discoveries into successful therapeutics can be difficult. Clinical Trials in Neurology aims to improve the efficiency of clinical trials and the development of interventions in order to enhance the development of new treatments for neurologic diseases. It introduces the reader to the key concepts underpinning trials in the neurosciences. This volume tackles the challenges of developing therapies for neurologic disorders from measurement of agents in the nervous system to the progression of clinical signs and symptoms through illustrating specific study designs and their applications to different therapeutic areas. Clinical Trials in Neurology covers key issues in Phase I, II and III clinical trials, as well as post-marketing safety surveillance. Topics addressed include regulatory and implementation issues, outcome measures and common problems in drug development. Written by a multidisciplinary team, this comprehensive guide is essential reading for neurologists, psychiatrists, neurosurgeons, neuroscientists, statisticians and clinical researchers in the pharmaceutical industry.

Biomedical Informatics in Translational Research

Biomedical Informatics in Translational Research Book
Author : Hai Hu,Richard J. Mural,Michael N. Liebman
Publisher : Artech House
Release : 2008
ISBN : 159693039X
Language : En, Es, Fr & De

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Book Description :

This trailblazing resource on biomedical informatics provides medical researchers with innovative techniques for integrating and federating data from clinical and molecular studies. This volume helps researchers manage data, expedite their efforts, and make the most of targeted basic research.

APS Observer

APS Observer Book
Author : Anonim
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download APS Observer book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

National Institute of Justice Journal

National Institute of Justice Journal Book
Author : Anonim
Publisher : Unknown
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download National Institute of Justice Journal book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

New Scientist

New Scientist Book
Author : Anonim
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download New Scientist book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Research Report

Research Report Book
Author : Anonim
Publisher : Unknown
Release : 1999
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Research Report book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

BMJ

BMJ Book
Author : Anonim
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download BMJ book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Basic Science of Oncology Fifth Edition

Basic Science of Oncology  Fifth Edition Book
Author : Ian Tannock,Richard Hill,Robert Bristow,Lea Harrington
Publisher : McGraw Hill Professional
Release : 2013-09-22
ISBN : 0071813497
Language : En, Es, Fr & De

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Book Description :

NOW IN FULL COLOR! Discover the science of cancer--with this newly revised, essential introduction to cancer biology and genetics Here in one well-organized, reader-friendly volume, you'll find everything you must know about the biology underlying cancer and its treatment, supported by the latest peer-reviewed research. Written by preeminent oncology researchers and clinicians, the book highlights the full range of important oncology topics and takes you through the biological basis of current and future biological therapy as well as more traditional approaches to cancer treatment. Presented in full color, the Fifth Edition of The Basic Science of Oncology is thoroughly updated and refreshed to reflect the latest critical thinking in oncology. For graduate students, oncologists, residents, and fellows, there can be no more useful guide to the bedrock science and practice of oncology than this all-in-one reference. FEATURES: The most current, evidence-based oncology primer--one that encapsulates the science of cancer causation, cancer biology, and cancer therapy Key insights into molecular and genetic aspects of cancer familiarize you with cancer biology as applied to prognosis and personalized cancer medicine In-depth focus on the discovery, evaluation, and biology of anti-cancer drugs, immunotherapy, and molecularly-targeted agents Up-to-date coverage of the basic science of radiation therapy Specific chapters/sections on intratumor heterogeneity as it relates to potential new treatment strategies--including tumor microenvironment and metabolism, tumor stem cells, and genomic/proteomic heterogeneity NEW! Chapter Essentials synthesize chapter content in a convenient list NEW! Color diagrams and schematics summarize important data

Cancer Research

Cancer Research Book
Author : Anonim
Publisher : Unknown
Release : 2001-07
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Annals of the Academy of Medicine Singapore

Annals of the Academy of Medicine  Singapore Book
Author : Academy of Medicine (Singapore)
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Annals of the Academy of Medicine Singapore book written by Academy of Medicine (Singapore), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.