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Design Of Nanostructures For Theranostics Applications

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Design of Nanostructures for Theranostics Applications

Design of Nanostructures for Theranostics Applications Book
Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Release : 2018-01-15
ISBN : 0128136707
Language : En, Es, Fr & De

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Book Description :

Design of Nanostructures for Theranostics Applications focuses on the theranostics applications of nanostructures. In particular, multifunctional nanoparticles for diagnostics and treatment of different diseases, including those relating to the blood-brain barrier, are discussed in detail. Chapters explore different type of nanostructures, covering design, fabrication, functionalization and optimization, helping readers obtain the desired properties. Written by a diverse range of international academics, this book is a valuable reference resource for those working in both nanoscience and the pharmaceutical industry. Explores how the design of a range of nanomaterials make them effective theranostic agents, including multifunctional core-shell nanostructures, mesoporous silica nanoparticles, and quantum dots Shows how nanomaterials are used effectively for a range of diseases, including breast cancer, prostate cancer and neurological disorders Assesses the pros and cons of using different nanomaterials for different types of treatment

Design of Nanostructures for Versatile Therapeutic Applications

Design of Nanostructures for Versatile Therapeutic Applications Book
Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Release : 2018-02-03
ISBN : 0128136685
Language : En, Es, Fr & De

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Book Description :

Design of Nanostructures for Versatile Therapeutic Applications focuses on antimicrobial, antioxidant and nutraceutical applications of nanostructured materials. Many books discuss these subjects, but not from a pharmaceutical point-of-view. This book covers novel approaches related to the modulation of microbial biofilms, antimicrobial therapy and encapsulate polyphenols as antioxidants. Written by an internationally diverse group of academics, this book is an important reference resource for researchers, both in biomaterials science and the pharmaceutical industry. Assesses the most recently developed nanostructures that have potential antimicrobial properties, explaining their novel mechanical aspects Shows how nanoantibiotics can be used to more effectively treat disease Provides a cogent summary of recent developments in nanoantimicrobial discovery, allowing readers to quickly familiarize themselves with the topic

Advances in Nanotheranostics I

Advances in Nanotheranostics I Book
Author : Zhifei Dai
Publisher : Springer
Release : 2015-12-15
ISBN : 3662485443
Language : En, Es, Fr & De

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Book Description :

This book highlights the recent advances in nanotheranostics from basic research to potential applications, and discusses the modular design and engineering of multiplex nanoparticles including gold nanostructures, luminescent nanoparticles, dendrimers and liposomes. Each chapter demonstrates multifunctional nanoparticles with topics covering targeting, imaging, delivery, diagnostics, and therapy as new modalities for cancer theranostics. This comprehensive book presents expert views on the latest developments in theranostic nanomedicine. It focuses on potential theranostic applications of multifunctional nanoparticles ranging from identifying noninvasively cancer cells by molecular detection, and visualizing in vivo drug delivery by means of contrast enhanced imaging, to destroying cancer cell s with minimal side effects via selective accumulation at tumor sites, and real-time monitoring therapeutic effectiveness. It also presents an interdisciplinary survey of nanotheranostics and as such is a valuable resource for researchers and students in related fields. Zhifei Dai is a Professor at the Department of Biomedical Engineering, College of Engineering, Peking University, China.

Nanostructures for the Engineering of Cells Tissues and Organs

Nanostructures for the Engineering of Cells  Tissues and Organs Book
Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Release : 2018-02-14
ISBN : 0128136669
Language : En, Es, Fr & De

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Book Description :

Nanostructures for the Engineering of Cells: Tissues and Organs showcases recent advances in pharmaceutical nanotechnology, with particular emphasis on tissue engineering, organ and cell applications. The book provides an up-to-date overview of organ targeting and cell targeting using nanotechnology. In addition, tissue engineering applications, such as skin regeneration are also discussed. Written by a diverse range of international academics, this book is a valuable research resource for researchers working in the biomaterials, medical and pharmaceutical industries. Explains how nanomaterials regulate different cell behavior and function as a carrier for different biomolecules Shows how nanobiomaterials and nanobiodevices are used in a range of treatment areas, such as skin tissue, wound healing and bone regeneration Discusses nanomaterial preparation strategies for pharmaceutical application and regenerative medicine

Design and Development of New Nanocarriers

Design and Development of New Nanocarriers Book
Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Release : 2017-12-12
ISBN : 0128136286
Language : En, Es, Fr & De

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Book Description :

Design and Development of New Nanocarriers focuses on the design and development of new nanocarriers used in pharmaceutical applications that have emerged in recent years. In particular, the pharmaceutical uses of microfluidic techniques, supramolecular design of nanocapsules, smart hydrogels, polymeric micelles, exosomes and metal nanoparticles are discussed in detail. Written by a diverse group of international researchers, this book is a valuable reference resource for those working in both biomaterials science and the pharmaceutical industry. Shows how nanomanufacturing techniques can help to create more effective, cheaper pharmaceutical products Explores how nanofabrication techniques developed in the lab have been translated to commercial applications in recent years Explains safety and regulatory aspects of the use of nanomanufacturing processes in the pharmaceutical industry

Multifunctional Theranostic Nanomedicines in Cancer

Multifunctional Theranostic Nanomedicines in Cancer Book
Author : Malay K. Das
Publisher : Academic Press
Release : 2021-03-26
ISBN : 0128217006
Language : En, Es, Fr & De

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Book Description :

Multifunctional Theranostic Nanomedicines in Cancer focuses on new trends, applications, and the significance of novel multifunctional nanotheranostics in cancer imaging for diagnosis and treatment. Cancer nanotechnology offers new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions—including targeting, imaging, and therapy—have been intensively studied with the goal of overcoming the limitations of conventional cancer diagnosis and therapy. Thus theranostic nanomedicines have emerged in recent years to provide an efficient and safer alternative in cancer management. This book covers polymer-based therapies, lipid-based therapies, inorganic particle-based therapies, photo-related therapies, radiotherapies, chemotherapies, and surgeries. Multifunctional Theranostic Nanomedicines in Cancer offers an indispensable guide for researchers in academia, industry, and clinical settings; it is also ideal for postgraduate students; and formulation scientists working on cancer. Provides a comprehensive resource of recent scientific progress and novel applications of theranostic nanomedicines Discusses treatment options from a pharmaceutical sciences perspective Includes translational science and targeted CNS cancer treatment

Core Shell Nanostructures for Drug Delivery and Theranostics

Core Shell Nanostructures for Drug Delivery and Theranostics Book
Author : Maria Focarete,Anna Tampieri
Publisher : Woodhead Publishing
Release : 2018-06-29
ISBN : 0081021992
Language : En, Es, Fr & De

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Book Description :

Core-Shell Nanostructures for Drug Delivery and Theranostics: Challenges, Strategies and Prospects for Novel Carrier Systems contains valuable chapters that deal with the fundamentals of nanotechnology for drug delivery, recent developments and research in core-shell nanoparticles for drug-delivery and theranostic applications, and the potential and applications of core-shell nanofiber. This book is a highly valuable resource for scientists interested in the design and development of innovative drug delivery systems, researchers and graduate/postdoctoral students engaged in biomaterials for drug delivery, and R&D managers in the biomaterials and pharmaceutical industry. Focuses on core-shell nanoparticles and nanofiber for innovative applications, including cancer therapy, controlled release and multi-drug release Considers future prospects and potential new applications of core-shell nanostructures for drug delivery and theranostics Explains the principles and essential concepts of nanotechnology for drug delivery systems

Nucleic Acid Nanotheranostics

Nucleic Acid Nanotheranostics Book
Author : Marco Filice,Jesús Ruiz-Cabello
Publisher : Elsevier
Release : 2019-02-26
ISBN : 0128144718
Language : En, Es, Fr & De

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Book Description :

Nucleic Acid Nanotheranostics: Biomedical Applications offers a comprehensive overview of improvements and new trends in fabrication of nanostructures as theranostic multifunctional carriers in gene therapy. With a strong focus on medical applications (comprising diagnosis, therapy and imaging), the book also examines gene therapy in an individual patient’s cells or tissues to treat genetic diseases. Sections cover Biomedical and Diagnostic applications of Nucleic Acids, Biologic and Synthetic Advanced Nanostructures for nucleic acid delivery, and important considerations of nanomedicine. This book is a valuable guide for materials scientists, physicians, chemists and engineers, but is also ideal for clinicians wishing to expand their knowledge. Provides a unique source of knowledge (theoretical as well as practical) on nanotheranostic materials for gene therapy at all levels and related scientific areas Covers the pros and cons related to viral and nanomaterial-based delivery of nucleic acids in terms of biosafety, carrier selection, synthesis and bioimaging Presents the only book to include an analysis of nanoformulations approved for clinical use

Clinical Applications of Magnetic Nanoparticles

Clinical Applications of Magnetic Nanoparticles Book
Author : Nguyen Tk Thanh
Publisher : CRC Press
Release : 2018
ISBN : 9781138051553
Language : En, Es, Fr & De

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Book Description :

Controlling the size and the shape of uniform magnetic iron oxide nanoparticles for biomedical applications / Helena Gavilán, María Eugenia Fortes Brollo, Lucía Gutiérrez, Sabino Veintemillas-Verdaguer and María del Puerto Morales -- Magnetic nanochains : properties, syntheses and prospects / Irena Milosevic, Vincent Russier, Marie-Louise Saboungi, Laurence Motte -- Carbon coated magnetic metal nanoparticles for clinical applications / Martin Zeltner and Robert N. Grass -- Bio-inspired magnetic nanoparticles for biomedical applications / Changqian Cao, Yongxin Pan -- Main challenges in surface biofunctionalization of magnetic nanoparticles for in vivo targeting / Laurent Adumeau, Marie-Hélène Delville and Stéphane Mornet -- Experimental considerations for scalable magnetic nanoparticle synthesis and surface functionalization for clinical applications / Alec P. LaGrow, Maximilian O. Besenhard, Roxanne Hachani and Nguyen T.H. Kim Thanh -- Magnetic polymersomes for MRI and theranostic applications / Adeline Hannecart, Dimitri Stanicki, Luce Vander Elst, Robert N. Muller, Sophie Laurent -- Ultra-small iron oxide nanoparticles stabilized with multidentate polymers for applications in MRI / Jung Kwon (John) Oh and Marc-André Fortin -- Encapsulation and release of drugs from magnetic silica nanocomposites / Damien Mertz and Sylvie Bégin-Colin -- Current progress in magnetic separation-aided biomedical diagnosis technology / Sim Siong Leong, Swee Pin Yeap, Siew Chun Low, Rohimah Mohamud and JitKang Lim -- Magnetic separation in integrated micro analytical systems / Kazunori Hoshino -- Magnetic nanoparticles for organelle separation / Mari Takahashi & Shinya Maenosono -- Magnetic nanoparticle based biosensing / Kai Wu, Diqing Su, Yinglong Feng, and Jian-Ping Wang -- Immunotoxicity and safety considerations for iron oxide nanoparticles / Gary Hannon, Melissa Anne Tutty, Adriele Prina-Mello -- Impact of core and functionalized magnetic nanoparticles on human health / Bella B. Manshian, Uwe Himmelreich, Stefaan J. Soenen -- Magnetic nanoparticles for cancer treatment using magnetic hyperthermia / Laura Asin, Grazyna Stepien, Maria Moros, Raluca M. Fratila, and Jesus M. de la Fuente -- Nanoparticles for nanorobotic agents dedicated to cancer therapy / Mahmood Mohammadi [and 6 others] -- Smart nanoparticles and the effects in magnetic hyperthermia in vivo / Ingrid Hilger -- Non-invasive guidance scheme of magnetic nanoparticles for drug delivery in Alzheimer's disease / Ali Kafash Hoshiar [and 5 others] -- Design, fabrication, and characterization of magnetic porous PDMS as an on-demand drug delivery device / Ali Shademani, Hongbin Zhang, Mu Chiao -- Magnetic particle transport in complex media / Lamar O. Mair [and 7 others] -- Magnetic nanoparticles for neural engineering / Gerardo F. Goya, Vittoria Raffa -- Radionuclide labeling and imaging of magnetic nanoparticles / Benjamin P. Burke, Christopher Cawthorne and Stephen J. Archibald -- Red blood cells constructs to prolong the life span of iron-based magnetic resonance imaging/magnetic particle imaging contrast agents in vivo / Antonella Antonelli, Mauro Magnani -- Stimuli-regulated cancer theranostics based on magnetic nanoparticles / Yanmin Ju, Shiyan Tong, and Yanglong Hou -- Good manufacturing practices (GMP) of magnetic nanoparticles / Emre Tuereli and Nazende Guenday Tuereli

Nanomedicine

Nanomedicine Book
Author : Yi Ge,Songjun Li,Shenqi Wang,Richard Moore
Publisher : Springer
Release : 2014-12-01
ISBN : 1461421403
Language : En, Es, Fr & De

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Book Description :

Increasing demand for and awareness of the applications of nanotechnology in medicine has resulted in the emergence of a new fast-growing multidisciplinary area - nanomedicine. This book offers comprehensive knowledge of and diverse perspectives on nanomedicine through two independent volumes. It aims to bridge the gap between nanotechnology and medicine through contributions by world-renowned experts from wide range of backgrounds including academia, industry, professional consultancy, and government agencies. Each contribution integrates knowledge from a wide range of areas to present the fundamentals of new applications and products of nanomedicine, as well as an outlook for the future. This book can well serve as a reference and guide for students, academics, researchers, scientists, engineers, clinicians, government researchers, and healthcare professionals.

Design Synthesis Multifunctionalization and Biomedical Applications of Multifunctional Mesoporous Silica Based Drug Delivery Nanosystems

Design  Synthesis  Multifunctionalization and Biomedical Applications of Multifunctional Mesoporous Silica Based Drug Delivery Nanosystems Book
Author : Yu Chen
Publisher : Springer
Release : 2015-10-14
ISBN : 3662486229
Language : En, Es, Fr & De

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Book Description :

This thesis reports on essential advances in the design, synthesis and biomedical applications of multifunctional Mesoporous Silica Nanoparticles (MSNs). It provides several examples of multifunctional MSN-based drug delivery nanosystems and demonstrates successful synergistic cancer therapies combining MSNs and high-intensity focused ultrasound. The book will especially be of interest to researchers and graduate students in the fields of biomaterials, biology, chemistry, medicine and the life sciences who are working to develop new methods and technologies to combat cancer.

Multifunctional Nanoparticles for Drug Delivery Applications

Multifunctional Nanoparticles for Drug Delivery Applications Book
Author : Sonke Svenson,Robert K. Prud'homme
Publisher : Springer Science & Business Media
Release : 2012-02-22
ISBN : 1461423058
Language : En, Es, Fr & De

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Book Description :

This book clearly demonstrates the progression of nanoparticle therapeutics from basic research to applications. This book, unlike others covering nanoparticles used in medical applications, presents the medical challenges that can be reduced or even overcome by recent advances in nanoscale drug delivery. Each chapter highlights recent progress in the design and engineering of select multifunctional nanoparticles with topics covering targeting, imaging, delivery, diagnostics, and therapy.

Nano Oncologicals

Nano Oncologicals Book
Author : Maria José Alonso,Marcos Garcia-Fuentes
Publisher : Springer
Release : 2014-10-15
ISBN : 3319080849
Language : En, Es, Fr & De

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Book Description :

This authoritative volume focuses on emerging technologies in cancer nano medicine, characterized by their multi-functionality and potential to address simultaneously diverse issues of clinical relevance in the treatment of cancer. The book consists of sixteen chapters divided into six sections: 1) Biological Barriers in Cancer; 2) Tumor Targeting; 3) Targeting the Immune System; 4) Gene Therapy; 5) Nano theranostics and 6) Translational Aspects of Nano-Oncologicals. The volume starts with an introduction describing the biological barriers associated with cancer therapy and highlighting ways to overcome such barriers through the use of nanotechnology. This is followed by an analysis of the two major targeting strategies currently under investigation in cancer therapy: namely, the targeting of cancer cells and the targeting of the immune system. In the first case, the book presents liposomal and polymer-based therapies, including photodynamic approaches. In the second case, it analyzes in detail the possibility of either improving the efficiency of the immune system toward preventing cancer progression (cancer immunomodulation) or generating responses against specific cancer antigens (cancer vaccines). Beyond these targeting options, Nano-Oncologicals: New Targeting and Delivery Approaches presents the most recent technological advances in the area of nucleic acid-based therapies, along with those in the area of theranostics, where the design of multifunctional nano carriers becomes vital. Following the study of the most promising nanotechnologies around the development of nano-oncologicals, the book ends with an overview of regulatory and toxicological issues, which are critical in their translational pathway, and the presentation of a nucleic acid-based therapy case-study. This book is an important resource for scientists interested in the design and development of anticancer nanotechnologies and also to those aiming to push their technology through clinical development.

Drug Delivery Nanosystems

Drug Delivery Nanosystems Book
Author : Natassa Pippa,Costas Demetzos,Stergios Pispas
Publisher : CRC Press
Release : 2019-01-15
ISBN : 0429955227
Language : En, Es, Fr & De

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Book Description :

Nanotechnology seeks to exploit distinct technological advances controlling the structure of nanoscale biomaterials at a nanodimensional scale approaching individual molecules and their aggregates or supramolecular structures. The term "nanomedicine" is used to describe those technologies under the umbrella of nanotechnology that have therapeutic applications in human health. This book presents recent trends and research achievements in the field of pharmaceutical nanotechnology and advanced drug delivery nanosystems, especially for theranostic purposes. The applications of drug delivery nanosystems considered carriers of active pharmaceutical ingredients (APIs) (e.g., proteins, peptides, and nucleic acids) are analyzed on the basis of technology, preparation protocols, and biomedical applications. The book also extensively reports on the principles, design protocols, and applications of nanosystems in drug delivery, imaging, and targeting of active molecules of pharmaceutical interest.

Multifunctional Nanocarriers for Contemporary Healthcare Applications

Multifunctional Nanocarriers for Contemporary Healthcare Applications Book
Author : Barkat, Md. Abul,A.B., Harshita,Beg, Sarwar,Ahmad, Farhan J.
Publisher : IGI Global
Release : 2018-01-12
ISBN : 1522547827
Language : En, Es, Fr & De

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Book Description :

Advances in technology permeates every aspect of life, including the healthcare system. Nanotechnology based systems have gained popularity based upon their promise, size, and other characteristics. Multifunctional Nanocarriers for Contemporary Healthcare Applications is a critical academic publication that explores advancements in nanostructured systems, applications of these systems in healthcare, and biomedical applications of these systems. Featuring coverage on a wide range of topics, such as hydrogels, controlled drug delivery systems, and nanomedicine, this book is geared toward researchers, students, and academicians seeking current research on advancements and applications of nanostructured systems in the healthcare industry.

Nanopharmaceutics

Nanopharmaceutics Book
Author : Xing-Jie Liang
Publisher : World Scientific
Release : 2013
ISBN : 9814368660
Language : En, Es, Fr & De

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Book Description :

Nanomaterials, with their unique size-dependent physical and chemical properties, have shown promising advantages as drug and gene delivery vehicles, ultra-sensitive intracellular detectors and novel therapeutic drugs. Nanopharmaceutics is one of the disciplines that will benefit the most from this technology. Nanotechnology will have a revolutionary impact on cancer diagnosis and therapy due to the exceptional characteristics of nanopharmaceutics. This book provides an overview of some tools, methods, and materials of nanotechnology that offer potential applications in pharmaceutics, followed by a series of examples showing applications that are already in development. It may very well inspire researchers to develop a new generation of pharmaceutics with inventive non-traditional approach and employ nanoscale science for the benefit of the patient.

Design and Development of Nanoparticles for Imaging and X ray Induced Photodynamic Therapy

Design and Development of Nanoparticles for Imaging and X ray Induced Photodynamic Therapy Book
Author : Geoffrey D. S. Wang
Publisher : Unknown
Release : 2017
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The development of nanomaterials and nanosystems for biomedical applications is an area of considerable current interest in chemistry, materials science, and medicine. The basic rationale is that nanometer-sized particles have unique optical, electronic, or magnetic properties that are not available from either discrete molecules or bulk solids. Also, nanosized structures or scaffolds are well suited for covalent attachment and/or noncovalent encapsulation of multiple diagnostic and therapeutic agents, leading to theranostic (both therapy and diagnostic) and related multi-modal systems. In this context, the primary objective of this dissertation was to design and develop innovative nanoparticles for cancer imaging and therapy. For optical and MRI cancer imaging, we have developed dual-modality inorganic/organic nanostructures by embedding gadolinium (a magnetic contrast agent) into fluorescent carbon dots or europium-doped metal-organic frameworks (MOF). These nanoparticle probes show excellent in-vivo stability, strong fluorescence emission and improved magnetic contrast, moreover the gadolinium carbon dots are small enough (about 12 nm in diameter) for rapid renal clearance. For cancer therapy, we have developed x-ray induced photodynamic nanoparticles by coating a nanoscintilator core with mesoporpous silica and photosensitizers. In comparison with traditional photodynamic therapy (PDT), the use of x-ray to activate photosensitizing drugs allows greater tissue penetration and photodynamic treatment of deeply buried tumors. Also, in-vivo therapeutic studies using orthotopic cancer models have shown that x-ray induced PDT is a combination of photodynamic therapy and radiotherapy that synergistically target the cellular membrane and cellular DNA. Taken together, these findings provide important insights into the design and development of multi-modal nanoparticles for cancer molecular imaging and targeted therapy.

Nanomedicines for Breast Cancer Theranostics

Nanomedicines for Breast Cancer Theranostics Book
Author : Nanasaheb D. Thorat,Joanna Bauer
Publisher : Elsevier
Release : 2020-03-08
ISBN : 0128200170
Language : En, Es, Fr & De

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Book Description :

Nanomedicines for Breast Cancer Theranostics addresses the translational aspects and clinical perspectives of breast cancer nanomedicine from a multidisciplinary perspective. The book summarizes research efforts at the preclinical and clinical stage of nanostructures and nanomedicine for dealing with the important challenge of nanomedicine translation in breast cancer theranostics. This book is an important resource for those working in both academia and industry, focusing on hot topics in biomaterials, biomedical engineering, drug delivery and oncology. Shows how the discovery of new nanomedicines is leading directly to an increase in the early-stage diagnosis of breast cancer Includes coverage of breast cancer nanomedicine standardization and characterization, highlighting newly developed treatments, diagnostics and treatment monitoring tools Explains why the design of nanobiomaterials make them effective drug carriers when treating breast cancer

Nanotechnology Applications for Tissue Engineering

Nanotechnology Applications for Tissue Engineering Book
Author : Sabu Thomas,Yves Grohens,Neethu Ninan
Publisher : William Andrew
Release : 2015-01-03
ISBN : 0323353037
Language : En, Es, Fr & De

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Book Description :

Tissue engineering involves seeding of cells on bio-mimicked scaffolds providing adhesive surfaces. Researchers though face a range of problems in generating tissue which can be circumvented by employing nanotechnology. It provides substrates for cell adhesion and proliferation and agents for cell growth and can be used to create nanostructures and nanoparticles to aid the engineering of different types of tissue. Written by renowned scientists from academia and industry, this book covers the recent developments, trends and innovations in the application of nanotechnologies in tissue engineering and regenerative medicine. It provides information on methodologies for designing and using biomaterials to regenerate tissue, on novel nano-textured surface features of materials (nano-structured polymers and metals e.g.) as well as on theranostics, immunology and nano-toxicology aspects. In the book also explained are fabrication techniques for production of scaffolds to a series of tissue-specific applications of scaffolds in tissue engineering for specific biomaterials and several types of tissue (such as skin bone, cartilage, vascular, cardiac, bladder and brain tissue). Furthermore, developments in nano drug delivery, gene therapy and cancer nanotechonology are described. The book helps readers to gain a working knowledge about the nanotechnology aspects of tissue engineering and will be of great use to those involved in building specific tissue substitutes in reaching their objective in a more efficient way. It is aimed for R&D and academic scientists, lab engineers, lecturers and PhD students engaged in the fields of tissue engineering or more generally regenerative medicine, nanomedicine, medical devices, nanofabrication, biofabrication, nano- and biomaterials and biomedical engineering. Provides state-of-the-art knowledge on how nanotechnology can help tackling known problems in tissue engineering Covers materials design, fabrication techniques for tissue-specific applications as well as immunology and toxicology aspects Helps scientists and lab engineers building tissue substitutes in a more efficient way

Silica coated Magnetic Nanoparticles

Silica coated Magnetic Nanoparticles Book
Author : Mariela A. Agotegaray,Verónica L. Lassalle
Publisher : Springer
Release : 2017-01-04
ISBN : 3319501585
Language : En, Es, Fr & De

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Book Description :

This brief offers a comprehensive discussion of magnetic targeted drug delivery of silica-coated nanodevices. Focusing on the latest trend in pharmaceutical applications of these nanodevices, a multidisciplinary overview is displayed, from synthesis and design to pharmacokenetics, biodistribution and toxicology. Chapters include design of silica-coated magnetic nanodevices; techniques for drug loading with features applicable to biological systems; synthesis, characterization and the assessment of biomedical issues with both in vitro and in vivo experiments. Applications in the treatment of different localized diseases are also addressed in order to present the potential use of these nanosystems as global, commercially available therapeutics.