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Cytokines And The Brain

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Cytokines and the Brain

Cytokines and the Brain Book
Author : Anonim
Publisher : Elsevier
Release : 2008-06-18
ISBN : 9780080559353
Language : En, Es, Fr & De

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Book Description :

This book opens a new page of neuro-immunobiology providing substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. The volume is a collection of complex, new data drawn from multiple areas of investigation in the field. The contents summarize current understanding on the presence and function of CNS cytokines and their receptors in a variety of CNS cells during health and disease. The chapters are a collection of complex, new data demonstrating the presence and synthesis of cytokines in brain cells, as well as their receptors on cell membranes in health and disease. The strength of the volume are the descriptions of the authors own investigations, together with those of others in the field pertaining to a large number of cytokines in brain function, as well as mechanisms involved in the development of CNS disorders, including multiple sclerosis and Alzheimer’s disease. Also included are novel approaches to the treatment of CNS disorders based on new experimental data. The contributors to this volume are internationally known scientists and clinical researchers in their respective fields of investigation and treatment. *Opens a new page of neuro-immunobiology and provides substantive evidence for the promise of this field in the treatment of disease *Summarizes current understanding on the presence and function of central nervous system (CNS) cytokines and their receptors in a variety of CNS cells during health and disease *Includes novel approaches to the treatment of CNS disorders based on new experimental data *Offers new insight into triggers for the development of autoimmune diseases in the brain and the possibilities for treatment

Brain Neurosecretory Cytokines

Brain Neurosecretory Cytokines Book
Author : Armen A. Galoyan
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1441988939
Language : En, Es, Fr & De

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Book Description :

Brain Neurosecretory Cytokines: Immune Response and Neuronal Survival summarizes the biological and chemical data of signal molecules of the brain neuroendocrine immune system, mainly proline-rich peptides, which play an important role in the regulation of immune response, neuronal survival, hematopoiesis, and adaptation. The author also describes the role of PRPs for the protection of neurons against neurodegenerative disturbances and diseases. Brain Neurosecretory Cytokines: Immune Response and Neuronal Survival will be of great aid to the researchers and students in various areas of neurobiological profile (neurochemistry, neuroendocrinology, neurophysiology, and endocrinology).

Psychoneuroimmunology

Psychoneuroimmunology Book
Author : Anonim
Publisher : Elsevier
Release : 2011-10-10
ISBN : 9780080465012
Language : En, Es, Fr & De

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Book Description :

Psychoneuroimmunology is the study of interactions among behavioral, neural and endocrine, and immunologic processes of adaptation. These two volumes provide a clearly written, extensively referenced summary of some of the behavioral, neural and endocrine regulators of immune responses and immunologically mediated disease processes and of the behavioral and neuroendocrine effects of immune system activity. Several chapters expand upon topics reviewed in earlier editions of this series; most chapters cover active areas of research that have not previously been reviewed. As illustrated in this fourth edition, interdisciplinary research continues to provide evidence that the brain and immune system represent a single, integrated system of defense. Fully revised and updated fourth edition of the classic reference Provides a neuroendocrine and immunologic perspective for the behavioral scientist Provides a behavioral and neuroscience perspective for the immunologist Helps the reader translate basic science findings into clinically relevant information Provides the reader with the background for and foundation of integrative research and integrative medicine Provides an encyclopedic resource for advanced undergraduates and for pre- and post-doctoral students as well as active researchers

Stress and the Brain

Stress and the Brain Book
Author : Steven E. Hyman
Publisher : Routledge
Release : 2013-10-23
ISBN : 1317970977
Language : En, Es, Fr & De

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Book Description :

First published in 2002. Routledge is an imprint of Taylor & Francis, an informa company.

The Brain and Host Defense

The Brain and Host Defense Book
Author : Anonim
Publisher : Elsevier
Release : 2009-12-24
ISBN : 9780444535450
Language : En, Es, Fr & De

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Book Description :

It is now well recognized that the brain, and especially the hypothalamus, plays an important role in the regulation of immune reactions and inflammation. This book aims to review our current state of knowledge of this important field. Key historical findings are presented, and the reciprocal interactions between the brain and the immune system are examined. Particular emphasis is placed on inflammation, a critical host defense reaction that serves as an effector response for both the adaptive and innate immune systems. Mechanisms implicated in brain defense, as well as in more general host defense, are discussed. The regulatory influences of the brain on inflammatory responses are included with particular reference to the role of the hypothalamus, which is also the main director the hormonal regulation of immune/inflammatory. Gender-related differences in immune responsiveness, circadian modulator of immune responses, and evidence that behavioral conditioning (e.g. reward) of immune responses is possible are used as examples to reinforce the notion that the neuroendocrine system exerts a fundamental and complex regulatory influence on the immune system. * Presents timely issues such as immunological aspects of the blood-brain-barrier and the role of inflammatory mediators in the evolution of strokes and degenerative diseases * Includes analysis of the role of the brain in the adaptive responses to disease * Evaluates the argument that further knowledge of the influence of the brain on the immune system will provide new insights to the pathophysiology infectious and autoimmune diseases

Cytokines and Pain

Cytokines and Pain Book
Author : L.R. Watkins,S.F. Maier
Publisher : Springer Science & Business Media
Release : 1999
ISBN : 9783764358495
Language : En, Es, Fr & De

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Book Description :

The purpose of this book is to examine immune-to-brain communication from the viewpoint of its effect on pain processing, and to clarify the major role that substances released by immune cells play in pain modulation. In these chapters, contributed by major laboratories whose focus is understanding how cytokines modulate pain, the perspectives examined range from evolutionary approaches across diverse species, to the basics of the immune response, to the effect of cytokines on peripheral and central nervous system sites, to therapeutic potential in humans. -- book cover.

Hormones Brain and Behavior Five Volume Set

Hormones  Brain and Behavior  Five Volume Set Book
Author : Anonim
Publisher : Elsevier
Release : 2002-06-18
ISBN : 0080534155
Language : En, Es, Fr & De

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Book Description :

Hormones, Brain and Behavior, Third Edition offers a state-of-the-art overview of hormonally-mediated behaviors, including an extensive discussion of the effects of hormones on insects, fish, amphibians, birds, rodents, and humans. Entries have been carefully designed to provide a valuable source of information for students and researchers in neuroendocrinology and those working in related areas, such as biology, psychology, psychiatry, and neurology. This third edition has been substantially restructured to include both foundational information and recent developments in the field. Continuing the emphasis on interdisciplinary research and practical applications, the book includes articles aligned in five main subject sections, with new chapters included on genetic and genomic techniques and clinical investigations. This reference provides unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics. The topics cover an unusual breadth (from molecules to ecophysiology), ranging from basic science to clinical research, making this reference of interest to a broad range of scientists in a variety of fields. Key Features * Contributors from 16 different countries and more than 70 institutions * Unlike any other hormone reference on the market Hormones, Brain and Behavior addresses hormone effects in all major vertebrate and non-vertebrate models * A timely, current reference on an emerging field with each chapter providing an in-depth exploration of the topic * Discusses molecular aspects of hormone function, systems, development, and hormone-related diseases * Addresses hormone effects in both the developing and adult nervous system Topics include: * Mammalian and Non-mammalian Hormone-behavior Systems * Cellular and Molecular Mechanisms of Hormone Actions on Behavior * Development of Hormone-dependent Neuronal Systems * Hormone/Behavior Relations of Clinical Importance

Neurobiology of Cytokines

Neurobiology of Cytokines Book
Author : Errol B. De Souza
Publisher : Academic Press
Release : 2013-10-22
ISBN : 1483217558
Language : En, Es, Fr & De

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Book Description :

Neurobiology of Cytokines, Part A provides an overview of the effects of cytokines in the brain and in the endocrine system. The book discusses the general aspects of cytokines, including the endogenous agonists and antagonists, their receptors, their second messengers, and transport mechanisms for cytokines across the blood-brain barrier. The text also describes the anatomical localization of cytokines, cytokine receptors, and their respective mRNA in brain and in endocrine tissues. The methods for evaluating the in vivo as well as in vitro actions of cytokines on hormone secretion are also considered. The book further tackles the synthesis and release of cytokines and their central nervous system actions; and the methodology for studying the role of cytokines in human neuropathological conditions.

Neurobiology of Cytokines

Neurobiology of Cytokines Book
Author : Errol B. DeSouza
Publisher : Academic Press
Release : 2013-10-22
ISBN : 1483288315
Language : En, Es, Fr & De

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Book Description :

Recent data suggest a critical role for cytokines in the regulation of brain and endocrine function under normal physiological conditions. The aim of this volume and its companion Volume 16 is to provide an overview of the effects of cytokines in the brain and in the endocrine system. Methods presented for easy adaptation to new systems Comprehensive protocols included for: The synthesis and release of cytokines; The study of their central nervous system actions; Studying the role of cytokines in human neuropathological conditions

Neuroimmunology of Sleep

Neuroimmunology of Sleep Book
Author : S. R. Pandi-Perumal,Daniel P. Cardinali,Georgios Chrousos
Publisher : Springer Science & Business Media
Release : 2007-08-19
ISBN : 0387691464
Language : En, Es, Fr & De

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Book Description :

This timely work reflects the growing importance of research into the nature of sleep and its medical aspects. One of the first of its kind, this work on the neuroimmunology of sleep provides an introduction to the interplay between these two key and interlinked areas. Written both from a basic and a clinical perspective, the volume is an invaluable information resource for biomedical professionals and students of the human biology. Highly practical guide written from both a basic and clinical perspective.

Reviews and Perspectives in Physiology 2000

Reviews and Perspectives in Physiology 2000 Book
Author : The Physiological Society
Publisher : Cambridge University Press
Release : 2000-04-06
ISBN : 9780521795111
Language : En, Es, Fr & De

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Book Description :

Brings together the Perspectives and Topical Reviews published during 1999 in The Journal of Physiology.

Stress and Your Health

Stress and Your Health Book
Author : Hymie Anisman
Publisher : John Wiley & Sons
Release : 2015-02-12
ISBN : 1118850335
Language : En, Es, Fr & De

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Book Description :

Stress and Your Health: From Vulnerability to Resilience presents an evidence-based evaluation of the various effects of stress, along with methods to alleviate distress and stress-related illnesses. Examines myriad stressor effects and proven ways to alleviate stress in our lives Covers a wide range of stressor-related topics including therapeutic strategies to deal with stress and factors that hinder treatment of stress Makes difficult biochemical and immunological concepts accessible to a non-specialist audience Addresses many of the factors that cause individuals to be more vulnerable to the impact of stressors and at increased risk for pathology

Psychoneuroimmunology

Psychoneuroimmunology Book
Author : Manfred Schedlowski,Uwe Tewes
Publisher : Springer Science & Business Media
Release : 1999
ISBN : 9780306459757
Language : En, Es, Fr & De

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Book Description :

This textbook examines the complex functional relationships between the nervous system, the neuroendocrine and the immune system. The international leaders in this field have been brought together to create this text; each contributing from their area of expertise. The result is a comprehensive yet accessible interdisciplinary introduction to psychoneuroimmunology which also takes you further than the foundations of those fascinating topics by covering research in HIV/AIDS, autoimmune diseases, and the reactivation of latent herpes viruses. Attention is also given to the effects of behaviour such as physical exercise, sleep, acute and chronic stress, and conditioning of immune functions in animals and humans. The whole is brought together with a wealth of cited research studies, and over 200 illustrations.

Cytokines and Cytokine Receptors

Cytokines and Cytokine Receptors Book
Author : Constantin A. Bona,Jean-Pierre Revillard
Publisher : CRC Press
Release : 2001-03-07
ISBN : 9789057026348
Language : En, Es, Fr & De

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Book Description :

The field of cytokine research is expanding at a rapid pace Contributions from the major leading groups in the world on the structure and biological properties of cytokine and cytokine receptors, as well as integrated reviews on cytokines in various physiological and pathological conditions were presented in three issues of International Reviews of Immunology This collection of articles provided a unique source of information However, important discoveries are emerging very rapidly and some of the reviews written in 1997 are already outdated In this book, the editors assemble reviews that have been updated by their authors to include all the recent publications and unpublished data from the authors' laboratories This volume should serve as an excellent reference source for all those concerned by the multiple faces of cytokines in basic research and in the clinic

Cytokines

Cytokines Book
Author : Robert E. Faith,Anthony J. Murgo,Robert A. Good,Nicholas P. Plotnikoff
Publisher : CRC Press
Release : 2006-10-10
ISBN : 1420003801
Language : En, Es, Fr & De

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Book Description :

Cytokine involvement in the immune system's response to stress is now very well documented. Cytokine activity has been implicated in a variety of mental and physical diseases, and has been shown to have a significant role in fueling the vicious circle of depression and illness. The first edition of Cytokines: Stress and Immunity pointed out

Neurobiology of Cytokines

Neurobiology of Cytokines Book
Author : Errol B. DeSouza
Publisher : Unknown
Release : 2013
ISBN : 9780121852832
Language : En, Es, Fr & De

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Book Description :

Recent data suggest a critical role for cytokines in the regulation of brain and endocrine function under normal physiological conditions. The aim of this volume and its companion Volume 16 is to provide an overview of the effects of cytokines in the brain and in the endocrine system. Key Features * Methods presented for easy adaptation to new systems * Comprehensive protocols included for: * The synthesis and release of cytokines * The study of their central nervous system actions * Studying the role of cytokines in human neuropathological conditions ...

Cytokines and the CNS

Cytokines and the CNS Book
Author : Richard M. Ransohoff,Etty N. Benveniste
Publisher : CRC Press
Release : 2005-10-31
ISBN : 9780849316227
Language : En, Es, Fr & De

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Book Description :

Provides Insight into How Cytokine Action Impacts the Physiology and Pathology of the CNS. As with the first edition of Cytokines and the CNS, this completely updated and revised edition introduces neurobiologists to cytokine biology and immunologists to the unique functions of cytokines in CNS physiology. The dramatically accelerating interest in cytokines and cytokine/chemokine signaling over the past several years has encouraged an explosion of literature on cytokines. The similarity between factors involved in inflammation or immunity, and those implicated in neural development, physiology, and repair has become so apparent that familiarity with cytokines must now be considered an essential element in the neurobiologist’s cognitive tool-kit. Conversely, for immunobiologists, the concepts elaborated by neurobiologists to understand developmental patterning and networked organ function continue to evolve in such a way that comprehension of cytokine action in the CNS can only enhance a further understanding of immune system function. Cytokines and the CNS, Second Edition is patterned after the first edition; however, the wealth of knowledge now available adds a tremendous amount of insight and new implications. To guarantee a fresh perspective, the editors made a conscious choice to utilize an entirely new set of contributors, all experts in various aspects of cytokine research. Cytokines and the CNS, Second Edition starts with a chapter on the CNS, focusing on pathological reactions to insult. Next, come three chapters on cytokine biology, followed by four chapters that integrate cytokine biology into basic CNS processes (development; inflammation; immunity; degeneration/repair), after which five chapters apply this body of knowledge to disease or pathology. The book closes with a look at the application of cytokine biology to the treatment of disease, a brand new area of research.

Inflammation and Stroke

Inflammation and Stroke Book
Author : Giora Z. Feuerstein
Publisher : Springer
Release : 2012-12-06
ISBN : 3034882971
Language : En, Es, Fr & De

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Book Description :

Stroke is a leading cause of death in developed countries. However, current therapeutic strategies for stroke have been largely unsuccessful. One possible explanation is that research and pharmacological management have focused on very early events in brain ischemia. New research has shown that brain ischemia and trauma elicit strong inflammatory reactions driven by both external and brain cells. The recognition of inflammation as a fundamental response to brain ischemia provides novel opportunities for new anti-inflammatory therapies. For the first time, an international body of researchers presents the latest findings about the cellular and humoral aspects of immune and inflammatory reactions in the brain. The work may have an impact on the treatment of neuroinjuries and ancillary brain diseases, and increase the understanding of the roles infections and immune reactions play in the brain milieu.

Cytokines and Mental Health

Cytokines and Mental Health Book
Author : Ziad Kronfol
Publisher : Springer Science & Business Media
Release : 2003-01-31
ISBN : 9781402073533
Language : En, Es, Fr & De

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Book Description :

Cytokines and Mental Health explores the relationship between cytokines, neural circuitry and mental health. It is interdisciplinary and "translational", bringing together information that spans the spectrum from the molecular and cellular levels to the patient and the clinic. Content includes chapters that discuss cytokine pathways in the brain, the neurochemical and neuroendocrine effects of cytokines, and the behavioral effects of cytokines including sickness behavior. These chapters in basic research are followed by a more clinical section that discusses the role of cytokines in neuropsychiatric disorders such as major depression, schizophrenia and Alzheimer's disease. The book offers different things to different people. It should be of great interest to neuroscientists and immunologists working in the field of psychoneuroimmunology. It would also greatly benefit mental health professionals including psychiatrists, psychologists and clinicians of diverse background who are interested in mind-body medicine.