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Cytogenomics

Cytogenomics Book
Author : Thomas Liehr
Publisher : Academic Press
Release : 2021-07-15
ISBN : 9780128235799
Language : En, Es, Fr & De

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Book Description :

With Cytogenomics, Editor Thomas Liehr and leading contributors in the field demonstrate that chromosomes are crucial to understanding the human genome, and that new high throughput approaches are central to advancing cytogenetics in the 21st century. After an introduction to molecular cytogenetics, this book highlights the strengths and newfound advantages of cytogenomic research methods and technologies, enabling researchers to jumpstart their own projects, and more effectively gather and interpret chromosomal data. Methods discussed include molecular cytogenetics, molecular karyotyping, GPCR, next generation sequencing, optical mapping, karyo-mapping, CRISPR-cas9, chromothripsis, and molecular combing. The book's second half examines recent applications of cytogenomic approaches, such as characterizing 3D chromosome-structure across different tissue types, topologically associated domains, and chromothripsis. Offers applied approaches empowering a new generation of cytogenetic research using advanced chromatography methods and state-of-the art sequencing technology Provides a framework for interpreting chromosome structure and how this affects the functioning of the genome in health and disease Features chapter contributions from international leaders in the field

Human Interphase Chromosomes

Human Interphase Chromosomes Book
Author : Ivan Iourov
Publisher : Springer International Publishing
Release : 2021-05-11
ISBN : 303062532X
Language : En, Es, Fr & De

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Book Description :

Download Human Interphase Chromosomes book written by Ivan Iourov, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Genome and Genomics

Genome and Genomics Book
Author : K. V. Chaitanya
Publisher : Springer Nature
Release : 2019-11-17
ISBN : 9811507023
Language : En, Es, Fr & De

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Book Description :

This book provides a detailed and up-to-dated information on the genomes belonging to three major life forms on Earth – archaea, prokaryotes and eukaryotes. Each section describes about the genome of a specific group of organisms, such as viruses, archaea, bacteria, eukaryotes and organellar genomes. Individual chapters provide details of their organization, structure, evolution, sequencing strategies and functions. Further, this book discusses the technologies that are applied for genome sequencing; assembly, annotation and gene prediction. Other topics include the genomes of important model organisms, mitochondria genome of Neanderthal fossil, etc. This book also examines the evolution of chloroplast and mitochondria genomes by comparing with bacteria, addresses the diseases that occur in humans due to the mutations in mitochondrial genome, gene therapy and engineering of chloroplast and mitochondrial genomes. Lastly, it features an overview of the role of proteomics, exposomics, connectomics, metabolomics, and microbiomics. This book is a fascinating read for students, lecturers and researchers in the field of genetics, genomics, microbiology and life sciences.

Investigations Into the Organellar Genomes of Higher Plants with a Focus on the Cucumber Cucumis Sativus L Mitochondrial Genome

Investigations Into the Organellar Genomes of Higher Plants with a Focus on the Cucumber  Cucumis Sativus L   Mitochondrial Genome Book
Author : Jason Warren Lilly
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Investigations Into the Organellar Genomes of Higher Plants with a Focus on the Cucumber Cucumis Sativus L Mitochondrial Genome book written by Jason Warren Lilly, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

PlantOmics The Omics of Plant Science

PlantOmics  The Omics of Plant Science Book
Author : Debmalya Barh,Muhammad Sarwar Khan,Eric Davies
Publisher : Springer
Release : 2015-03-18
ISBN : 8132221729
Language : En, Es, Fr & De

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Book Description :

PlantOmics: The Omics of Plant Science provides a comprehensive account of the latest trends and developments of omics technologies or approaches and their applications in plant science. Thirty chapters written by 90 experts from 15 countries are included in this state-of-the-art book. Each chapter describes one topic/omics such as: omics in model plants, spectroscopy for plants, next generation sequencing, functional genomics, cyto-metagenomics, epigenomics, miRNAomics, proteomics, metabolomics, glycomics, lipidomics, secretomics, phenomics, cytomics, physiomics, signalomics, thiolomics, organelle omics, micro morphomics, microbiomics, cryobionomics, nanotechnology, pharmacogenomics, and computational systems biology for plants. It provides up to date information, technologies, and their applications that can be adopted and applied easily for deeper understanding plant biology and therefore will be helpful in developing the strategy for generating cost-effective superior plants for various purposes. In the last chapter, the editors have proposed several new areas in plant omics that may be explored in order to develop an integrated meta-omics strategy to ensure the world and earth’s health and related issues. This book will be a valuable resource to students and researchers in the field of cutting-edge plant omics.

BioScan

BioScan Book
Author : Anonim
Publisher : Unknown
Release : 2009
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Principles and Applications of Molecular Diagnostics

Principles and Applications of Molecular Diagnostics Book
Author : Nader Rifai,A. Rita Horvath,Carl T. Wittwer,Jason Park
Publisher : Elsevier
Release : 2018-06-13
ISBN : 0128160624
Language : En, Es, Fr & De

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Book Description :

Principles and Applications of Molecular Diagnostics serves as a comprehensive guide for clinical laboratory professionals applying molecular technology to clinical diagnosis. The first half of the book covers principles and analytical concepts in molecular diagnostics such as genomes and variants, nucleic acids isolation and amplification methods, and measurement techniques, circulating tumor cells, and plasma DNA; the second half presents clinical applications of molecular diagnostics in genetic disease, infectious disease, hematopoietic malignancies, solid tumors, prenatal diagnosis, pharmacogenetics, and identity testing. A thorough yet succinct guide to using molecular testing technology, Principles and Applications of Molecular Diagnostics is an essential resource for laboratory professionals, biologists, chemists, pharmaceutical and biotech researchers, and manufacturers of molecular diagnostics kits and instruments. Explains the principles and tools of molecular biology Describes standard and state-of-the-art molecular techniques for obtaining qualitative and quantitative results Provides a detailed description of current molecular applications used to solve diagnostics tasks

Human Genome Informatics

Human Genome Informatics Book
Author : Christophe Lambert,Darrol Baker,George P. Patrinos
Publisher : Academic Press
Release : 2018-08-02
ISBN : 0128134313
Language : En, Es, Fr & De

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Book Description :

Human Genome Informatics: Translating Genes into Health examines the most commonly used electronic tools for translating genomic information into clinically meaningful formats. By analyzing and comparing interpretation methods of whole genome data, the book discusses the possibilities of their application in genomic and translational medicine. Topics such as electronic decision-making tools, translation algorithms, interpretation and translation of whole genome data for rare diseases are thoroughly explored. In addition, discussions of current human genome databases and the possibilities of big data in genomic medicine are presented. With an updated approach on recent techniques and current human genomic databases, the book is a valuable source for students and researchers in genome and medical informatics. It is also ideal for workers in the bioinformatics industry who are interested in recent developments in the field. Provides an overview of the most commonly used electronic tools to translate genomic information Brings an update on the existing human genomic databases that directly impact genome interpretation Summarizes and comparatively analyzes interpretation methods of whole genome data and their application in genomic medicine

Iscn 2016

Iscn 2016 Book
Author : J. McGowan-Jordan,M. Schmid,A. Simons
Publisher : Unknown
Release : 2016-05-11
ISBN : 9783318058574
Language : En, Es, Fr & De

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Book Description :

The 2016 edition of the International System for Human Cytogenomic Nomenclature (ISCN 2016) offers standard nomenclature that is used to describe any genomic rearrangement identified by techniques ranging from karyotyping to FISH, microarray, various region specific assays, and DNA sequencing. Suggestions from the international cytogenetics community have been reviewed by the Standing Committee, an international group of experts, nominated by their peers. This updated edition offers: * many new examples, particularly for microarray and region specific assays * trackable changes in the main text compared to the previous edition for easier identification * a nomenclature standard to facilitate the description of chromosome rearrangements characterized by DNA sequencing developed through collaboration between the Human Genome Variation Society (HGVS) and ISCN to accommodate the increased use of sequencing technologies in the characterization of chromosomal abnormalities The ISCN 2016 is an indispensable reference volume for human cytogeneticists, molecular geneticists, technicians, and students for the interpretation and communication of human cytogenetic and molecular cytogenomic nomenclature. After a long collaboration with Cytogenetic and Genome Research, ISCN is now again a part of this leading journal on chromosome and genome research, combining the day-to-day business with the latest findings.

Iscn 2020

Iscn 2020 Book
Author : Jean McGowan-Jordan,Ros J. Hastings,Sarah Moore
Publisher : Unknown
Release : 2020-12-31
ISBN : 9783318067064
Language : En, Es, Fr & De

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Book Description :

This reprint of 'Cytogenetic and Genome Research' contains contributions discussing the subject in-depth. 'Cytogenetic and Genome Research' is a well-respected, international peer-reviewed journal in genetics.

Cytogenomic Analyses of the Genus Sorghum

Cytogenomic Analyses of the Genus Sorghum Book
Author : Jason C. Anderson
Publisher : Unknown
Release : 2011
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

A phylogenetic tree based on ITS1, Adh1 and ndhF grouped the species of the genus Sorghum into one distinct monophyletic group, but including two sister lineages, one with x=5, the other with x=10 as basic chromosome numbers. The goal of this study was to elucidate major patterns in Sorghum genome evolution, particularly n=5 vs. n=10 genomes. A very recent molecular cytogenetic study in our laboratory revealed striking structural karyotypic rearrangements between S. bicolor (x=10) and an x=5 Sorghum species, S. angustum; so an immediate objective here was to determine if identical or similar rearrangements exist in other wild Sorghum species. Our approach was [1] to extend similar methods to additional species, i.e., fluorescent in situ hybridization (FISH) analyses of sorghum genomic bacterial artificial chromosome clones and multi-BAC cocktail probes to mitotic chromosomes of S. angustum, S. versicolor, S. brachypodum and S. intrans; and [2] to augment the BAC-FISH findings by comparing telomeric and ribosomal DNA FISH signal distributions to x=5 and x=10 Sorghum species. Signals from in situ hybridizations of BAC-based probes were insufficiently robust and insufficiently localized to delineate FISH signal patterns akin to those discovered previously in S. angustum. Southern blots of the same BACs to restricted DNA of these species revealed relatively moderate affinity to smeared DNA, suggesting homology to non-tandemized sequences. FISH of the A-type TRS (Arabidopsis-like telomeric repeat sequence) revealed its presence is limited to terminal chromosomal regions of the Sorghum species tested, except S. brachypodum, which displayed intercalary signal on one chromosome and no detachable signal at its termini region. The hybridization of 45S and 5S rDNA revealed that the respective sites of tandemized clusters differ among species in terms of size, number and location, except S. angustum versus S. versicolor. Well localized BAC-FISH signals normally occur when signals from low-copy sequences discernibly exceed background signal, including those from hybridization of dispersed repetitive elements. The low level of signal intensity from BAC low-copy sequences relative to the background signal "noise" seems most likely due to low homology and(or) technical constraints. Extensive dispersal of low-copy sequences that are syntenic in S. bicolor seems unlikely, but possible. In conclusion, the result was a lack of clear experimental success with BAC-FISH and an inability to effectively screen for S. angustum-like rearrangements using BAC-FISH. The telomeric and rDNA FISH indicated that the x=5 genomes vary extensively. One can surmise that although the arrangements seen in S. angustum might extend to S. versicolor, they certainly do not extend to S. versicolor, they certainly do not extend to S. intrans or S. brachypodum. It is clear that S. brachypodum has telomeric repeats that are either very short or rely on some sequence other than the A-type TRS.

Revue Roumaine de M decine

Revue Roumaine de M  decine Book
Author : Anonim
Publisher : Unknown
Release : 1982
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Tobacco Abstracts

Tobacco Abstracts Book
Author : Anonim
Publisher : Unknown
Release : 2001
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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The AGT Cytogenetics Laboratory Manual

The AGT Cytogenetics Laboratory Manual Book
Author : Marilyn S. Arsham,Margaret J. Barch,Helen J. Lawce
Publisher : John Wiley & Sons
Release : 2017-04-24
ISBN : 1119061229
Language : En, Es, Fr & De

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Book Description :

Cytogenetics is the study of chromosome morphology, structure, pathology, function, and behavior. The field has evolved to embrace molecular cytogenetic changes, now termed cytogenomics. Cytogeneticists utilize an assortment of procedures to investigate the full complement of chromosomes and/or a targeted region within a specific chromosome in metaphase or interphase. Tools include routine analysis of G-banded chromosomes, specialized stains that address specific chromosomal structures, and molecular probes, such as fluorescence in situ hybridization (FISH) and chromosome microarray analysis, which employ a variety of methods to highlight a region as small as a single, specific genetic sequence under investigation. The AGT Cytogenetics Laboratory Manual, Fourth Edition offers a comprehensive description of the diagnostic tests offered by the clinical laboratory and explains the science behind them. One of the most valuable assets is its rich compilation of laboratory-tested protocols currently being used in leading laboratories, along with practical advice for nearly every area of interest to cytogeneticists. In addition to covering essential topics that have been the backbone of cytogenetics for over 60 years, such as the basic components of a cell, use of a microscope, human tissue processing for cytogenetic analysis (prenatal, constitutional, and neoplastic), laboratory safety, and the mechanisms behind chromosome rearrangement and aneuploidy, this edition introduces new and expanded chapters by experts in the field. Some of these new topics include a unique collection of chromosome heteromorphisms; clinical examples of genomic imprinting; an example-driven overview of chromosomal microarray; mathematics specifically geared for the cytogeneticist; usage of ISCN’s cytogenetic language to describe chromosome changes; tips for laboratory management; examples of laboratory information systems; a collection of internet and library resources; and a special chapter on animal chromosomes for the research and zoo cytogeneticist. The range of topics is thus broad yet comprehensive, offering the student a resource that teaches the procedures performed in the cytogenetics laboratory environment, and the laboratory professional with a peer-reviewed reference that explores the basis of each of these procedures. This makes it a useful resource for researchers, clinicians, and lab professionals, as well as students in a university or medical school setting.

Biology and Management of Coregonid Fishes 2005

Biology and Management of Coregonid Fishes  2005 Book
Author : Małgorzata Jankun
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Coregonids (whitefish, vendace, cisco, etc.) are cold-water adapted fishes common throughout the Holarctic in North America, Europe and Asia. They have evolved into a myriad of forms, subspecies and species during and after the Pleistocene glaciations. They are therefore rich subjects for the study of evolutionary problems. Coregonids support important commercial, subsistence and recreational fisheries and are the subject of significant aquaculture operations around the world. Although coregonids are generally considered to be fairly adaptable to the pressures of exploitation, they do appear to be sensitive to changing environmental conditions such as eutrophication and a number of populations and species have been extirpated, usually by deteriorating environments coupled with the introduction of exotic species and by commercial exploitation. This sizeable volume contains 40 peer-reviewed contributions on current topics of coregonid research presented at the Ninth International Symposium on the Biology and Management of Coregonid Fishes, held in August 2005, in Olsztyn, Poland. They cover all aspects of coregonid life and managment. The contributions can be grouped into of five subject areas: genetics and evolution; biology, life history and population dynamics; invasive species; fisheries in Europe and fisheries in North America

Plant Genomes

Plant Genomes Book
Author : Jean-Nicolas Volff
Publisher : Karger Medical and Scientific Publishers
Release : 2008-01-01
ISBN : 3805584911
Language : En, Es, Fr & De

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Book Description :

Recent major advances in the field of comparative genomics and cytogenomics of plants, particularly associated with the completion of ambitious genome projects, have uncovered astonishing facets of the architecture and evolutionary history of plant genomes. The aim of this book was to review these recent developments as well as their implications in our understanding of the mechanisms which drive plant diversity. New insights into the evolution of gene functions, gene families and genome size are presented, with particular emphasis on the evolutionary impact of polyploidization and transposable elements. Knowledge on the structure and evolution of plant sex chromosomes, centromeres and microRNAs is reviewed and updated. Taken together, the contributions by internationally recognized experts present a panoramic overview of the structural features and evolutionary dynamics of plant genomes.This volume of Genome Dynamics will provide researchers, teachers and students in the fields of biology and agronomy with a valuable source of current knowledge on plant genomes.

Encyclopedia of Genetics Genomics Proteomics and Bioinformatics Genetics

Encyclopedia of Genetics  Genomics  Proteomics  and Bioinformatics  Genetics Book
Author : Lynn B. Jorde
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Encyclopedia of Genetics Genomics Proteomics and Bioinformatics Genetics book written by Lynn B. Jorde, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Indian Journal of Social Development

Indian Journal of Social Development Book
Author : Anonim
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Genetics Evolution and Conservation of Neotropical Fishes

Genetics  Evolution  and Conservation of Neotropical Fishes Book
Author : Rodrigo A. Torres,Roberto Ferreira Artoni
Publisher : Frontiers Media SA
Release : 2020-01-21
ISBN : 2889633357
Language : En, Es, Fr & De

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Book Description :

Fish represent the most ancestral and specious group of vertebrates, and occupy more diverse aquatic environments around the world. Ichthyofauna is extremely diverse, especially in megadiverse countries occupying biogeographical regions such as the Neotropical Region, which covers an extensive area between North and South America. Much of this biodiversity will be extinct, even before science knows any aspect of its biology. Like this, Neotropical fish genetics started in the end of the 70’s with papers studying the chromosomes of Hoplias malabaricus (Family Erythrinidae) and the karyotype variation among three genera of the family Anostomidae. The topic at that time was concentrated in two Institutions from the state of São Paulo, Southeastern Brazil. In the middle 80’s, the first Symposium on Neotropical Fish Cytogenetics was organized. Nowadays, the field of Neotropical Fish Genetics is present in Brazil, Colombia, Argentina, Uruguai, Venezula, Chile, and Equador, as well as outside South America in Panama, Mexico, USA, Canada, Czech Republic, Germany, and Spain. The research developed in cytogenetics has focused mainly on karyotype evolution and cytotaxonomy, chromosome structure and, more recently, cytogenomics. In relation to the use of molecular markers, support has been sought for the management of populations for conservation or production in captivity. In addition, many studies have been carried out with the aim of establishing supra-specific phylogenetic relationships and clarifying species distribution scenarios by phylogeographic modeling. The genome and transcriptome of some model species begin to emerge as extremely promising and informative areas for neotropical fish. In 2017, the Neotropical fish genetics research community celebrates the 30th anniversary of its main Meeting (today entitled Symposium on Neotropical Fish Genetics and Cytogenetics). This Research Topic is part of this celebration and aims at reporting the state of the art and its current advances in the frontier of knowledge in genetics, evolution, and conservation of neotropical fish, as well as to detect the challenges to be overcome in the next years.