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Consultative Hemostasis And Thrombosis

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Consultative Hemostasis and Thrombosis

Consultative Hemostasis and Thrombosis Book
Author : Craig S. Kitchens,Craig M. Kessler
Publisher : Elsevier
Release : 2018-08
ISBN : 9780323462020
Language : En, Es, Fr & De

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Book Description :

With authoritative coverage of rare and common hemostatic disorders, Consultative Hemostasis and Thrombosis, 4th Edition, keeps you both up to date with all that's new in this fast-moving field as well as reviewing background and development and citing pertinent classical literature. Broad differential diagnoses are provided, underscoring the editors' position that correct treatment begins with correct diagnosis. This trusted resource by Drs. Craig S. Kitchens, Craig M. Kessler, Barbara A. Konkle, Michael B. Streiff, and David A. Garcia is designed for rapid reference and critical decision making at the point of care. Emphasizes real-world problems and solutions, with quick access to concise descriptions of each condition, associated symptoms, laboratory findings, differential diagnosis, and treatment. Features a user-friendly design, full-color format, abundant laboratory protocols, and at-a-glance tables and charts throughout. Provides thorough updates on core information on hemostasis and thrombosis, including deep venous thrombosis (DVT), pulmonary embolisms, hypercoagulability, thrombocytopenia, von Willenbrand disease, and more. Covers new treatment information on hemophilia A and B. Contains new chapters on hereditary hemorrhagic telangiectasia, hemolytic uremic syndrome, and paroxymal nocturnal hemoglobinuria. Two new editors, Dr. Michael B. Streiff and Dr. David A. Garcia, offer fresh perspectives and valuable experience. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Consultative Hemostasis and Thrombosis E Book

Consultative Hemostasis and Thrombosis E Book Book
Author : Craig S. Kitchens,Barbara A Konkle,Craig M. Kessler
Publisher : Elsevier Health Sciences
Release : 2018-07-20
ISBN : 0323477852
Language : En, Es, Fr & De

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Book Description :

With authoritative coverage of rare and common hemostatic disorders, Consultative Hemostasis and Thrombosis, 4th Edition, keeps you both up to date with all that’s new in this fast-moving field as well as reviewing background and development and citing pertinent classical literature. Broad differential diagnoses are provided, underscoring the editors’ position that correct treatment begins with correct diagnosis. This trusted resource by Drs. Craig S. Kitchens, Craig M. Kessler, Barbara A. Konkle, Michael B. Streiff, and David A. Garcia is designed for rapid reference and critical decision making at the point of care.

Consultative Hemostasis and Thrombosis

Consultative Hemostasis and Thrombosis Book
Author : Craig S. Kitchens,Barbara M. Alving,Craig M. Kessler
Publisher : Elsevier Health Sciences
Release : 2007-09-12
ISBN : 1437710603
Language : En, Es, Fr & De

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Book Description :

Effectively and efficiently diagnose and manage today's full range of clotting and bleeding disorders using clinical case studies that demonstrate real-world problems and solutions! For each condition examined, you'll review concise descriptions of its associated symptoms, along with laboratory findings, diagnosis, differential diagnosis, and treatment - all the clinical guidance you need - at your fingertips. It's the ideal real-life reference tool for busy physicians! A reader-friendly design, coupled with nearly 385 illustrations and at-a-glance tables - many new to this edition - equip you to quickly locate the guidance you need. Abundant laboratory protocols enable you to select and interpret lab tests more easily. A complete section on women's health issues helps you stay current in this evolving area. A new chapter on the impact of herbal medicines examines their effect on hemostasis and their interaction with other drugs. New coverage of hemostatic issues in traumatology, sepsis, interventional radiology, pulmonology, and cardiology allows you to master the latest advances.

Consultative Hemostasis and Thrombosis

Consultative Hemostasis and Thrombosis Book
Author : Anonim
Publisher : Unknown
Release : 2015
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Consultative Hemostasis and Thrombosis book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Consultative Hemostasis and Thrombosis

Consultative Hemostasis and Thrombosis Book
Author : Craig S. Kitchens,Craig M. Kessler,Barbara A. Konkle
Publisher : Elsevier Health Sciences
Release : 2013
ISBN : 1455722960
Language : En, Es, Fr & De

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Book Description :

A unique clinical focus makes Consultative Hemostasis and Thrombosis, 3rd Edition your go-to guide for quick, practical answers on managing the full range of bleeding and clotting disorders. Emphasizing real-world problems and solutions, Dr. Craig S. Kitchens, Dr. Barbara A. Konkle, and Dr. Craig M. Kessler provide all the clinical guidance you need to make optimal decisions on behalf of your patients and promote the best possible outcomes. Efficiently look up concise descriptions of each condition, its associated symptoms, laboratory findings, diagnosis, differential diagnosis, and treatment.

Hemostasis and Thrombosis

Hemostasis and Thrombosis Book
Author : Thomas G. DeLoughery
Publisher : CRC Press
Release : 2004-01-01
ISBN : 1498713017
Language : En, Es, Fr & De

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Book Description :

This book offers a practical guide to recognizing, diagnosing, and managing patients with common and uncommon hemostatic and thrombotic disorders. It also presents up-to-date information on the novel antithrombotic agents introduced on the market. The book is intended for healthcare providers.

The Vein Book

The Vein Book Book
Author : John J. Bergan,Nisha Bunke-Paquette
Publisher : Oxford University Press
Release : 2014
ISBN : 0195399633
Language : En, Es, Fr & De

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Book Description :

The Vein Book provides complete, authoritative, and up-to-date information about venous function and dysfunction, bridging the gap between clinical medicine and basic science. It is the single most authoritative resource on veins and venous circulation.

Transfusion Medicine Apheresis and Hemostasis

Transfusion Medicine  Apheresis  and Hemostasis Book
Author : Huy P. Pham,Lance A. Williams, III
Publisher : Academic Press
Release : 2017-09-15
ISBN : 0128040300
Language : En, Es, Fr & De

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Book Description :

Transfusion Medicine, Apheresis, and Hemostasis: Review Questions and Case Studies is the collaborative effort that spanned a time period of 2 years and included 50 experts, many whom are national leaders in their respected fields. It also represents the passion and privilege we feel to teach the next generation of physicians in Transfusion Medicine and Apheresis. The main goal for this book is to help the readers build a solid foundation of both basic and advanced conceptual knowledge to prepare for the American Board of Pathology (ABP) certification exam in Transfusion Medicine. This book is not intended to be a substitute for textbooks, original research or review articles, and/or clinical training. Further, since the field of medicine, both from a scientific and regulatory perspective, rapidly changes, the readers are advised to continuously update their knowledge by attending national meetings and reading clinical journals. To equip the readers with the basic knowledge in critical reading and data analysis, which is an essential skill in daily medical practice, a novel chapter titled “Data Interpretation in Laboratory Medicine was included in this book. In this chapter, the readers are asked to make logical conclusions based on the given data and/or statistical results. Moreover, there is also a chapter on “Practical Calculations in Transfusion Medicine, Apheresis, and Hemostasis to help consolidate all the necessary formulas commonly used in daily practice for easy reference. These chapters are unique to our book and will not be found in any other currently on the market. All of the questions in this book were originally created by the authors of each chapter. Each question can either be standalone or part of a case scenario representing challenge cases in Transfusion Medicine, Apheresis, and Hemostasis. These questions often represent both rare and common clinical scenarios that the authors have seen during their clinical practice. Each question is then followed by 5 possible answers, with only one being correct (or the best answer). After the question, there is a conceptual explanation followed by a more factual explanation of the right and wrong answers. We gave the individual authors the freedom to choose how they explained the wrong answer choices. Some authors chose to be more direct (e.g. Answer A is incorrect because...), while other authors chose a more conversational style (e.g. Human resources (answer A) includes staffing, selection, orientation, training, and competency assessment of employees). This format is designed to help the student linking the conceptual and factual knowledge together to form a solid foundation for use in clinical practice. At the end of each chapter, there is a list of articles and textbooks that will prove useful to the motivated student who wishes to become an expert in the field. Another special feature to our textbook is the presence of a pre-test and post-test, which are provided to help the readers with self-assessment. As stated above, the main focus of this book is to help the readers preparing for the ABP certification exam in Transfusion Medicine. However, due to the interdisciplinary nature of the field of Transfusion Medicine, Apheresis, and Hemostasis, we believe that this book is also beneficial to and can be used by all clinicians involved in the management of complex transfusion, apheresis, and hemostasis issues, such as hematologists, anesthesiologists, surgeons, and critical care physicians. We further believe that it is a helpful guide for these specialists to prepare for their own specialty certification exam, when the topics are related to Transfusion Medicine, Apheresis, and Hemostasis.

Rodak s Hematology

Rodak s Hematology Book
Author : Elaine M. Keohane,Larry J. Smith,Jeanine M. Walenga
Publisher : Elsevier Health Sciences
Release : 2015-02-20
ISBN : 0323239064
Language : En, Es, Fr & De

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Book Description :

This book shows how to accurately identify cells, simplifies hemostasis and thrombosis concepts, and covers normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origins. This book also makes it easy to understand complementary testing areas such as flow cytometry, cytogenetics, and molecular diagnostics. Covers everything from working in a hematology lab to the parts and functions of the cell to laboratory testing of blood cells and body fluid cells.

Hematology E Book

Hematology   E Book Book
Author : Bernadette F. Rodak,Elaine M. Keohane,George A. Fritsma
Publisher : Elsevier Health Sciences
Release : 2013-12-27
ISBN : 0323292690
Language : En, Es, Fr & De

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Book Description :

Featuring hundreds of full-color photomicrographs, Hematology: Clinical Principles and Applications prepares you for a job in the clinical lab by exploring the essential aspects of hematology. It shows how to accurately identify cells, simplifies hemostasis and thrombosis concepts, and covers normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origins. This book also makes it easy to understand complementary testing areas such as flow cytometry, cytogenetics, and molecular diagnostics. Well-known authors Bernadette Rodak, George Fritsma, and Elaine Keohane cover everything from working in a hematology lab to the parts and functions of the cell to laboratory testing of blood cells and body fluid cells. Full-color illustrations make it easier to visualize complex concepts and show what you’ll encounter in the lab. Learning objectives begin each chapter, and review questions appear at the end. Instructions for lab procedures include sources of possible errors along with comments. Case studies provide opportunities to apply hematology concepts to real-life scenarios. Hematology instruments are described, compared, and contrasted. Coverage of hemostasis and thrombosis includes the development and function of platelets, the newest theories of normal coagulation, and clear discussions of platelet abnormalities and disorders of coagulation. A bulleted summary of important content appears at the end of every chapter. A glossary of key terms makes it easy to find and learn definitions. Hematology/hemostasis reference ranges are listed on the inside front and back covers for quick reference. Respected editors Bernadette Rodak, George Fritsma, and Elaine Keohane are well known in the hematology/clinical laboratory science world. Student resources on the companion Evolve website include the glossary, weblinks, and content updates. New content is added on basic cell biology and etiology of leukocyte neoplasias. Updated Molecular Diagnostics chapter keeps you current on techniques being used in the lab. Simplified hemostasis material ensures that you can understand this complex and important subject. Coverage of morphologic alteration of monocytes/macrophages is condensed into a table, as the disorders in this grouping are more of a biochemical nature with minimal hematologic evidence.

Rutherford s Vascular Surgery and Endovascular Therapy 2 Volume Set E Book

Rutherford s Vascular Surgery and Endovascular Therapy  2 Volume Set E Book Book
Author : Anton P Sidawy,Bruce A Perler
Publisher : Elsevier Health Sciences
Release : 2022-06-04
ISBN : 0323775608
Language : En, Es, Fr & De

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Book Description :

Encyclopedic, definitive, and state-of-the-art in the field of vascular disease and its medical, surgical, and interventional management, Rutherford's Vascular Surgery and Endovascular Therapy offers authoritative guidance from the most respected and innovative global thought leaders and clinical and basic science experts of our time. The thoroughly revised 10th Edition, published in association with the Society for Vascular Surgery and authored by multidisciplinary and international contributors, is an outstanding reference for vascular surgeons, vascular medicine specialists, interventional radiologists and cardiologists, and their trainees who depend upon Rutherford’s in their practice. Under the expert editorial guidance of Drs. Anton N. Sidawy and Bruce A. Perler, it is quite simply the most complete and most reliable resource available on the art and science of circulatory diseases. Incorporates fundamental vascular biology, diagnostic techniques, and decision making as well as medical, endovascular, and surgical treatment of vascular disease. Features numerous concise and comprehensive diagnostic and therapeutic algorithms vital to patient evaluation and management. Covers all vascular imaging techniques, offering a non-invasive evaluation of both the morphology and hemodynamics of the vascular system. Employs a full-color layout, images and online videos, so readers can view clinical and physical findings and operative techniques more vividly. Contains fully updated and more concise chapters with a focused format and summary for each that provides a quick access to key information—ideal for consultation as well as daily practice. Includes expanded coverage of the business of vascular surgery, including a new section on the use of technology platforms and social media, and new chapters on telemedicine, the development and operation of outpatient dialysis centers and multispecialty cardiovascular centers, vascular information on the internet, and much more. Provides new content on key topics such as endovascular treatment of complex aortic disease, acute vascular occlusion in the pediatric population, outpatient vascular care, and anatomic surgical exposures for open surgical reconstructions.

Anatomy Physiology with Brief Atlas of the Human Body and Quick Guide to the Language of Science and Medicine E Book

Anatomy   Physiology with Brief Atlas of the Human Body and Quick Guide to the Language of Science and Medicine   E Book Book
Author : Kevin T. Patton,Frank B. Bell,Terry Thompson,Peggie L. Williamson
Publisher : Elsevier Health Sciences
Release : 2022-03-21
ISBN : 0323875815
Language : En, Es, Fr & De

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Book Description :

A&P may be complicated, but learning it doesn't have to be! Anatomy & Physiology, 11th Edition uses a clear, easy-to-read approach to tell the story of the human body’s structure and function. Color-coded illustrations, case studies, and Clear View of the Human Body transparencies help you see the "Big Picture" of A&P. To jump-start learning, each unit begins by reviewing what you have already learned and previewing what you are about to learn. Short chapters simplify concepts with bite-size chunks of information. Conversational, storytelling writing style breaks down information into brief chapters and chunks of information, making it easier to understand concepts. 1,400 full-color photographs and drawings bring difficult A&P concepts to life and illustrate the most current scientific knowledge. UNIQUE! Clear View of the Human Body transparencies allow you to peel back the layers of the body, with a 22-page, full-color insert showing the male and female human body along several planes. The Big Picture and Cycle of Life sections in each chapter help you comprehend the interrelation of body systems and how the structure and function of these change in relation to age and development. Interesting sidebars include boxed features such as Language of Science and Language of Medicine, Mechanisms of Disease, Health Matters, Diagnostic Study, FYI, Sport and Fitness, and Career Choices. Learning features include outlines, key terms, and study hints at the start of each chapter. Chapter summaries, review questions, and critical thinking questions help you consolidate learning after reading each chapter. Quick Check questions in each chapter reinforce learning by prompting you to review what you have just read. UNIQUE! Comprehensive glossary includes more terms than in similar textbooks, each with an easy pronunciation guide and simplified translation of word parts — essential features for learning to use scientific and medical terminology! NEW! Updated content reflects more accurately the diverse spectrum of humanity. NEW! Updated chapters include Homeostasis, Central Nervous System, Lymphatic System, Endocrine Regulation, Endocrine Glands, and Blood Vessels. NEW! Additional and updated Connect It! articles on the Evolve website, called out in the text, help to illustrate, clarify, and apply concepts. NEW! Seven guided 3-D learning modules are included for Anatomy & Physiology.

Handbook of Venous and Lymphatic Disorders

Handbook of Venous and Lymphatic Disorders Book
Author : Peter Gloviczki,American Venous Forum
Publisher : CRC Press
Release : 2017-03-03
ISBN : 1498724418
Language : En, Es, Fr & De

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Book Description :

The Handbook of Venous Disorders, first published in 1996, is a handbook for all clinicians and surgeons who are involved with the investigation, evaluation, or management of venous and lymphatic diseases or malformations. These disorders include varicose veins, venous ulcers, DVT, lymphedema, and pulmonary embolism, as well as damage to the veins through trauma or tumor growth. The new edition has been completely updated to bring the book in line with current teaching practices.

Hemophilia and Hemostasis

Hemophilia and Hemostasis Book
Author : Alice D. Ma,Harold R. Roberts,Miguel A. Escobar
Publisher : John Wiley & Sons
Release : 2012-10-03
ISBN : 1118439309
Language : En, Es, Fr & De

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Book Description :

There is a general need amongst healthcare professionals for practical advice on the management of patients with bleeding disorders. This book is an essential resource for all those working in the fields of coagulation, hemostasis and thrombosis. It covers the major cases one might encounter in diagnosing, managing and treating hemophilia and hemostasis. It provides a practical and informative guide to the broad range of topics concerning both bleeding and clotting disorders. The book is divided into major chapter sections depending on the type of bleeding disorder it fits into. Each chapter includes a brief overview of the disorder covering: history of the disorder; molecular basis of the disorder; class presentation; genetics; current laboratory tests and monitoring. Cases associated with each disorder are presented alongside practical questions and answers from a wide range of contributors. As practice can vary from center to center, controversial areas are clearly marked and discussed throughout. New to this edition: coverage of the newer techniques; newer treatment modalities; new oral anticoagulants; update on hemophilia management; more on ITP and greater coverage of new cases as suggested by reviewers.

Rodak s Hematology E Book

Rodak s Hematology   E Book Book
Author : Elaine M. Keohane,Catherine N. Otto,Jeanine M. Walenga
Publisher : Elsevier Health Sciences
Release : 2019-02-22
ISBN : 0323549632
Language : En, Es, Fr & De

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Book Description :

Make sure you are thoroughly prepared to work in a clinical lab. Rodak’s Hematology: Clinical Principles and Applications, 6th Edition uses hundreds of full-color photomicrographs to help you understand the essentials of hematology. This new edition shows how to accurately identify cells, simplifies hemostasis and thrombosis concepts, and covers normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origins. Easy to follow and understand, this book also covers key topics including: working in a hematology lab; complementary testing areas such as flow cytometry, cytogenetics, and molecular diagnostics; the parts and functions of the cell; and laboratory testing of blood cells and body fluid cells. UPDATED nearly 700 full-color illustrations and photomicrographs make it easier for you to visualize hematology concepts and show what you’ll encounter in the lab, with images appearing near their mentions in the text to minimize flipping pages back and forth. UPDATED content throughout text reflects latest information on hematology. Instructions for lab procedures include sources of possible errors along with comments. Hematology instruments are described, compared, and contrasted. Case studies in each chapter provide opportunities to apply hematology concepts to real-life scenarios. Hematology/hemostasis reference ranges are listed on the inside front and back covers for quick reference. A bulleted summary makes it easy for you to review the important points in every chapter. Learning objectives begin each chapter and indicate what you should achieve, with review questions appearing at the end. A glossary of key terms makes it easy to find and learn definitions. NEW! Additional content on cell structure and receptors helps you learn to identify these organisms. NEW! New chapter on Introduction to Hematology Malignancies provides and overview of diagnostic technology and techniques used in the lab.

Hysteroscopy

Hysteroscopy Book
Author : Linda D. Bradley,Tommaso Falcone
Publisher : Elsevier Health Sciences
Release : 2008
ISBN : 0323041019
Language : En, Es, Fr & De

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Book Description :

This new text presents authoritative in-depth coverage of hysteroscopy, a quick in-office procedure for an accurate diagnosis of abnormal vaginal bleeding, uterine adhesions, foreign bodies, uterine structural defects, anatomic defects, and infertility. More than 380 full-color images provide a real-life practice perspective of the conditions you'll encounter. This procedure enables you to take a direct view of any pathology, without the risk of radiation exposure, and decreases the chances of uterine perforation. Chapters encompass a full range of clinical considerations, including instrumentation, imaging, complications, and endometrial ablation. Provides chapters that detail the instrumentation you'll need to effectively perform hysteroscopic procedures. Features a full chapter on imaging, including saline infusion sonography, keeping you current on the latest imaging technology. Offers expert guidance on endometrial ablation, a frequent office procedure used to diagnose and treat abnormal bleeding. Presents coverage of diagnostic and operative hysteroscopy, enabling you to incorporate this technology of increasing clinical use into your practice. Features a color design with more than 380 full-color images that highlight techniques and equip you with a real-life practice perspective.

Textbook of Hemophilia

Textbook of Hemophilia Book
Author : Christine A. Lee,Erik E. Berntorp,W. Keith Hoots
Publisher : John Wiley & Sons
Release : 2011-07-05
ISBN : 1444347705
Language : En, Es, Fr & De

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Book Description :

The Textbook of Hemophilia has become a definitive resource for all those managing hemophilia patients. It covers all the common and rare bleeding disorders, both in terms of clinical management as well as the genetic, laboratory, financial and psychological aspects. This second edition covers all the latest developments in the field of hemophilia, with new chapters on: the genetic and molecular basis of inherited blood disorders how to manage adolescent and older patients emergency medicine and inherited blood disorders national hemophilia databases Drawing on the vast experience of the authors, the aim of this textbook remains the same - to improve the care of patients suffering from hemophilia. The book is full of detailed guidance and advice on everyday clinical questions making it invaluable to all trainee and practicing hematologists.

Advances in Clinical Chemistry

Advances in Clinical Chemistry Book
Author : Gregory S. Makowski
Publisher : Academic Press
Release : 2020-01-10
ISBN : 0128208015
Language : En, Es, Fr & De

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Book Description :

Advances in Clinical Chemistry, Volume 94, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest technologies relating to the field of clinical chemistry, with specific chapters in this new release covering Hypertensive disorders of pregnancy: Strategy to develop clinical peptide biomarkers for more accurate evaluation of the pathophysiological status of this syndrome, Clotting factors - Clinical biochemistry and their roles as plasma enzymes, Myokines: The endocrine coupling of skeletal muscle and bone, Epigenetic reprogramming and potential application of epigenetic-modifying drugs in acquired chemotherapeutic resistance, and more. Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science Authored by world renowned clinical laboratory scientists, physicians and research scientists Presents the international benchmark for novel analytical approaches in the clinical laboratory

Handbook of Pediatric Transfusion Medicine

Handbook of Pediatric Transfusion Medicine Book
Author : Christopher D. Hillyer,Christopher Hillyer,Ronald Strauss,Naomi Luban
Publisher : Elsevier
Release : 2004-02-23
ISBN : 9780080491431
Language : En, Es, Fr & De

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Book Description :

Structured to be a companion to the recently published Handbook of Transfusion Medicine, the Handbook of Pediatric Transfusion Medicine is dedicated to pediatric hematology-oncology and transfusion medicine, a field which remains ambiguous and which has generated few comprehensive texts. This book stands alone as one of the few texts that addresses transfusion issues specific to pediatric medicine. Written in an eminently readable style, this authoritative handbook is a requirement for any pediatric physician or caregiver. Neonatal and fetal immune response and in utero development issues Blood compatability and pre-transfusion testing issues specific to pediatric and neonatal transfusion Therapeutic apheresis including red blood cell exchange and prophylactic chronic erythrocytapheresis for sickle cell patients Also includes a section that concentrates on the consent, quality and legal issues of blood transfusion and donation

Hematological Complications in Obstetrics Pregnancy and Gynecology

Hematological Complications in Obstetrics  Pregnancy  and Gynecology Book
Author : Rodger L. Bick,Eugene P. Frenkel,William F. Baker,Ravi Sarode
Publisher : Cambridge University Press
Release : 2006-04-20
ISBN : 1107320666
Language : En, Es, Fr & De

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Book Description :

There are many haematological complications associated with obstetrics, pregnancy and gynaecology, and unfortunately, they often lead to significant morbidity or mortality for both mother and child. As the first comprehensive reference on all aspects of haematological complications of obstetrics, pregnancy and gynaecology this book will be a valuable resource to haematologists, obstetricians, gynaecologists, reproductive medicine specialists, internists, anaesthesiologists and others. The chapters are written by acknowledged experts in the field, and for each condition covered the etiology, pathophysiology, clinical and laboratory diagnosis and management are discussed where appropriate.