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Concepts And Models For Drug Permeability Studies

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Concepts and Models for Drug Permeability Studies

Concepts and Models for Drug Permeability Studies Book
Author : Bruno Sarmento
Publisher : Woodhead Publishing
Release : 2015-09-30
ISBN : 0081001142
Language : En, Es, Fr & De

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Book Description :

This book intends to be an updated compilation of the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrier in vitro models for predicting the permeability of drugs. Concepts and Models for Drug Permeability Studies focuses on different approaches and comprises of various models. Each model describes the protocol of seeding and conservation, the application for specific drugs, and takes into account the maintenance of physiologic characteristics and functionality of epithelium, from the simplest immortalized cell-based monoculture to the most complex engineered-tissue models. Chapters also discuss the equivalence between in vitro cell and tissue models and in vivo conditions, highlighting how each model may provisionally resemble a different drug absorption route. Updated information regarding the most recent in vitro models to study the permeability of drugs Short and concise chapters covering all the biological barriers with interest in drug permeability A combination of bibliographic information related with individual models and footnote instructions of technical procedures for construction of cell and tissue-based models Simple and clear scientific content, adaptable for young scientists and experimented researchers

Characterization of Pharmaceutical Nano and Microsystems

Characterization of Pharmaceutical Nano  and Microsystems Book
Author : Leena Peltonen
Publisher : John Wiley & Sons
Release : 2020-10-27
ISBN : 1119414024
Language : En, Es, Fr & De

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Book Description :

Learn about the analytical tools used to characterize particulate drug delivery systems with this comprehensive overview Edited by a leading expert in the field, Characterization of Pharmaceutical Nano- and Microsystems provides a complete description of the analytical techniques used to characterize particulate drug systems on the micro- and nanoscale. The book offers readers a full understanding of the basic physicochemical characteristics, material properties and differences between micro- and nanosystems. It explains how and why greater experience and more reliable measurement techniques are required as particle size shrinks, and the measured phenomena grow weaker. Characterization of Pharmaceutical Nano- and Microsystems deals with a wide variety of topics relevant to chemical and solid-state analysis of drug delivery systems, including drug release, permeation, cell interaction, and safety. It is a complete resource for those interested in the development and manufacture of new medicines, the drug development process, and the translation of those drugs into life-enriching and lifesaving medicines. Characterization of Pharmaceutical Nano- and Microsystems covers all of the following topics: An introduction to the analytical tools applied to determine particle size, morphology, and shape Common chemical approaches to drug system characterization A description of solid-state characterization of drug systems Drug release and permeation studies Toxicity and safety issues The interaction of drug particles with cells Perfect for pharmaceutical chemists and engineers, as well as all other industry professionals and researchers who deal with drug delivery systems on a regular basis, Characterization of Pharmaceutical Nano- and Microsystems also belongs on bookshelves of interested students and faculty who interact with this topic.

Cumulated Index Medicus

Cumulated Index Medicus Book
Author : Anonim
Publisher : Unknown
Release : 1995
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cumulated Index Medicus book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Energy Research Abstracts

Energy Research Abstracts Book
Author : Anonim
Publisher : Unknown
Release : 1978
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Energy Research Abstracts book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

CONTROLLED DRUG DELIVERY BASIC CONCEPTS

CONTROLLED DRUG DELIVERY BASIC CONCEPTS Book
Author : Stephen D. Bruck
Publisher : CRC-Press
Release : 1983-04-12
ISBN : 9780849351815
Language : En, Es, Fr & De

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Book Description :

Download CONTROLLED DRUG DELIVERY BASIC CONCEPTS book written by Stephen D. Bruck, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Absorption and Drug Development Solubility Permeability and Charge State

Absorption and Drug Development  Solubility  Permeability  and Charge State Book
Author : Alex Avdeef
Publisher : John Wiley & Sons
Release : 2012-05-22
ISBN : 1118057457
Language : En, Es, Fr & De

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Book Description :

Explains how to perform and analyze the results of the latest physicochemical methods With this book as their guide, readers have access to all the current information needed to thoroughly investigate and accurately determine a compound's pharmaceutical properties and their effects on drug absorption. The book emphasizes oral absorption, explaining all the physicochemical methods used today to analyze drug candidates. Moreover, the author provides expert guidance to help readers analyze the results of their studies in order to select the most promising drug candidates. This Second Edition has been thoroughly updated and revised, incorporating all the latest research findings, methods, and resources, including: Descriptions and applications of new PAMPA models, drawing on more than thirty papers published by the author's research group Two new chapters examining permeability and Caco-2/MDCK and permeability and the blood-brain barrier Expanded information and methods to support pKa determination New examples explaining the treatment of practically insoluble test compounds Additional case studies demonstrating the use of the latest physicochemical techniques New, revised, and expanded database tables throughout the book Well over 200 drawings help readers better understand difficult concepts and provide a visual guide to complex procedures. In addition, over 800 references serve as a gateway to the primary literature in the field, facilitating further research into all the topics covered in the book. This Second Edition is recommended as a reference for researchers in pharmaceutical R&D as well as in agrochemical, environmental, and other related areas of research. It is also recommended as a supplemental text for graduate courses in pharmaceutics.

Concepts in Topical Drug Delivery

Concepts in Topical Drug Delivery Book
Author : Cecily Barbara Lalor
Publisher : Unknown
Release : 1994
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Medical Pharmacology Principles and Concepts

Medical Pharmacology  Principles and Concepts Book
Author : Andres Goth
Publisher : Unknown
Release : 1972
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Medical Pharmacology Principles and Concepts book written by Andres Goth, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Mammalian Cell Membranes General concepts

Mammalian Cell Membranes  General concepts Book
Author : Graham A. Jamieson,David Mason Robinson
Publisher : Butterworth-Heinemann
Release : 1976
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Mammalian Cell Membranes General concepts book written by Graham A. Jamieson,David Mason Robinson, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Concepts in Drug Metabolism

Concepts in Drug Metabolism Book
Author : Peter Jenner,Bernard Testa
Publisher : Marcel Dekker Incorporated
Release : 1980
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Concepts in Drug Metabolism book written by Peter Jenner,Bernard Testa, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Modern Concepts in Brain Tumor Therapy Laboratory and Clinical Investigations

Modern Concepts in Brain Tumor Therapy  Laboratory and Clinical Investigations Book
Author : Audrey E. Evans
Publisher : Unknown
Release : 1979
ISBN : 9780719400209
Language : En, Es, Fr & De

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Book Description :

Download Modern Concepts in Brain Tumor Therapy Laboratory and Clinical Investigations book written by Audrey E. Evans, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Safety Science Abstracts Journal

Safety Science Abstracts Journal Book
Author : Anonim
Publisher : Unknown
Release : 1978
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Safety Science Abstracts Journal book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Principles and Perspectives in Drug Bioavailability

Principles and Perspectives in Drug Bioavailability Book
Author : James Blanchard,Ronald J. Sawchuk,Bernard B. Brodie
Publisher : S Karger Ag
Release : 1979
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Principles and Perspectives in Drug Bioavailability book written by James Blanchard,Ronald J. Sawchuk,Bernard B. Brodie, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Peritoneum and Peritoneal Access

The Peritoneum and Peritoneal Access Book
Author : Stig Bengmark
Publisher : John Wright
Release : 1989
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Peritoneum and Peritoneal Access book written by Stig Bengmark, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Handbook of Physiology

Handbook of Physiology Book
Author : Anonim
Publisher : Unknown
Release : 1977
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Protein Binding and Drug Transport

Protein Binding and Drug Transport Book
Author : Jean-Paul Tillement,E. Lindenlaub
Publisher : Wiley-Liss
Release : 1986
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Protein Binding and Drug Transport book written by Jean-Paul Tillement,E. Lindenlaub, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Journal of Pharmacology and Experimental Therapeutics

The Journal of Pharmacology and Experimental Therapeutics Book
Author : Anonim
Publisher : Unknown
Release : 1977
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Physics Briefs

Physics Briefs Book
Author : Anonim
Publisher : Unknown
Release : 1983
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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