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Computational Immunology

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Computational Immunology

Computational Immunology Book
Author : Shyamasree Ghosh
Publisher : CRC Press
Release : 2019-10-14
ISBN : 135102552X
Language : En, Es, Fr & De

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Book Description :

The immune system is highly complex system with large number of macromolecules, signaling pathways, protein-protein interactions, and gene expressions. Studies from genomics, transcriptomics, metabolomics are generating huge high throughput data that needs to be analyzed for understanding the Immune system in Health and Disease. Computational approaches arehelping in understanding the study of complex biology of immunology and thereby enabling design of therapeutic strategies in diseases like infectious diseases, immunodeficiency, allergic, hypersensitive, autoimmune disorders and diseases like Cancer, HIV etc. Computational Immunology: Basics highlights the basics of the immune system and function in health and disease. This book offers comprehensive coverage of the most essential topics, including Overview of Immunology and computational Immunology Immune organs and cells, antigen, antibody, B, cell, T cell Antigen Processing and presentation Diseases due to abnormalities of the immune system Cancer Biology Shyamasree Ghosh (MSc, PhD, PGDHE, PGDBI), is currently working in the School of Biological Sciences, National Institute of Science Education and Research (NISER), Bhubaneswar, DAE, Govt of India, graduated from the prestigious Presidency College Kolkata in 1998. She was awarded the prestigious National Scholarship from the Government of India. She has worked and published extensively in glycobiology, sialic acids, immunology, stem cells and nanotechnology. She has authored several publications that include books and encyclopedia chapters in reputed journals and books.

Computational Immunology

Computational Immunology Book
Author : Shyamasree Ghosh
Publisher : CRC Press
Release : 2020-01-31
ISBN : 1351023497
Language : En, Es, Fr & De

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Book Description :

Computational Immunology: Applications focuses on different mathematical models, statistical tools, techniques, and computational modelling that helps in understanding complex phenomena of the immune system and its biological functions. The book also focuses on the latest developments in computational biology in designing of drugs, targets, biomarkers for early detection and prognosis of a disease. It highlights the applications of computational methods in deciphering the complex processes of the immune system and its role in health and disease. This book discusses the most essential topics, including Next generation sequencing (NGS) and computational immunology Computational modelling and biology of diseases Drug designing Computation and identification of biomarkers Application in organ transplantation Application in disease detection and therapy Computational methods and applications in understanding of the invertebrate immune system S Ghosh is MSc, PhD, PGDHE, PGDBI, is PhD from IICB, CSIR, Kolkata, awarded the prestigious National Scholarship from the Government of India. She has worked and published extensively in glycobiology, sialic acids, immunology, stem cells and nanotechnology. She has authored several publications that include books and encyclopedia chapters in reputed journals and books.

Computational Immunology

Computational Immunology Book
Author : Josep Bassaganya-Riera
Publisher : Academic Press
Release : 2015-10-21
ISBN : 0128037156
Language : En, Es, Fr & De

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Book Description :

Computational Immunology: Models and Tools encompasses the methodological framework and application of cutting-edge tools and techniques to study immunological processes at a systems level, along with the concept of multi-scale modeling. The book's emphasis is on selected cases studies and application of the most updated technologies in computational modeling, discussing topics such as computational modeling and its usage in immunological research, bioinformatics infrastructure, ODE based modeling, agent based modeling, and high performance computing, data analytics, and multiscale modeling. There are also modeling exercises using recent tools and models which lead the readers to a thorough comprehension and applicability. The book is a valuable resource for immunologists, computational biologists, bioinformaticians, biotechnologists, and computer scientists, as well as all those who wish to broaden their knowledge in systems modeling. Offers case studies with different levels of complexity Provides a detailed view on cutting-edge tools for modeling that are useful to experimentalists with limited computational skills Explores the usage of simulation for hypothesis generation, helping the reader to understand the most valuable points on experimental setting

Conceptual Modelling in Computational Immunology

Conceptual Modelling in Computational Immunology Book
Author : Martina Husáková
Publisher : Tomáš Bruckner
Release : 2015-09-10
ISBN : 8087924029
Language : En, Es, Fr & De

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Book Description :

Computational immunology offers in silico strategies for understanding of complex processes occurring in the natural immune system of a living organism that are difficult to explore by traditional in vivo or in vitro techniques. The monograph introduces conceptual languages and approaches for modelling biological processes. The Agent Modelling Language is investigated for conceptualisation of immune processes. AML-based diagrams represent properties and processes occurring in a lymph node.

Methods and Applications of Computational Immunology

Methods and Applications of Computational Immunology Book
Author : Victor Greiff,Gur Yaari,Johannes Textor,Benny Chain
Publisher : Frontiers Media SA
Release : 2020-01-30
ISBN : 2889633888
Language : En, Es, Fr & De

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Book Description :

Download Methods and Applications of Computational Immunology book written by Victor Greiff,Gur Yaari,Johannes Textor,Benny Chain, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Complex Systems and Computational Biology Approaches to Acute Inflammation

Complex Systems and Computational Biology Approaches to Acute Inflammation Book
Author : Yoram Vodovotz
Publisher : Springer Nature
Release : 2021-10-19
ISBN : 3030565106
Language : En, Es, Fr & De

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Book Description :

Download Complex Systems and Computational Biology Approaches to Acute Inflammation book written by Yoram Vodovotz, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

BIOMAT 2009

BIOMAT 2009 Book
Author : Anonim
Publisher : Unknown
Release : 2021-10-19
ISBN : 9814464961
Language : En, Es, Fr & De

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Book Description :

Download BIOMAT 2009 book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Immunological Computation

Immunological Computation Book
Author : Dipankar Dasgupta,Fernando Nino
Publisher : CRC Press
Release : 2008-09-12
ISBN : 9781420065466
Language : En, Es, Fr & De

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Book Description :

Clearly, nature has been very effective in creating organisms that are capable of protecting themselves against a wide variety of pathogens such as bacteria, fungi, and parasites. The powerful information-processing capabilities of the immune system, such as feature extraction, pattern recognition, learning, memory, and its distributive nature provide rich metaphors that researchers are finding very useful for the development of computational models. While some of these models are designed to give us a better understanding of the immune system, other models are being developed to solve complex real-world problems such as anomaly detection, pattern recognition, data analysis (clustering), function optimization, and computer security. Immunological Computation: Theory and Applications is devoted to discussing different immunological mechanisms and their relation to information processing and problem solving. This unique volume presents a compendium of up-to-date work related to immunity-based techniques. After presenting the general abstractions of immune elements and processes used in computational models, it then— Reviews standard procedures, representations, and matching rules that are used in all immunological computation models Covers the details of one of the earliest and most well-known immune algorithms, based on the negative selection (NS) process that occurs in the thymus Examines promising immune models, including those based on danger theory, cytokine network models, and MHC-based models The text goes further to describe a wide variety of applications, which include computer security, the detection and analysis of anomalies and faults, robotics, and data mining among others. To enhance understanding of this emerging field of study, each chapter includes a summary, review questions, and exercises for readers to practice; as well as issues that will require future research.

Computational Collective Intelligence

Computational Collective Intelligence Book
Author : Manuel Núñez,Ngoc Thanh Nguyen,David Camacho,Bogdan Trawiński
Publisher : Springer
Release : 2015-09-09
ISBN : 3319243063
Language : En, Es, Fr & De

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Book Description :

This two-volume set (LNAI 9329 and LNAI 9330) constitutes the refereed proceedings of the 7th International Conference on Collective Intelligence, ICCCI 2014, held in Madrid, Spain, in September 2015. The 110 full papers presented were carefully reviewed and selected from 186 submissions. They are organized in topical sections such as multi-agent systems; social networks and NLP; sentiment analysis; computational intelligence and games; ontologies and information extraction; formal methods and simulation; neural networks, SMT and MIS; collective intelligence in Web systems – Web systems analysis; computational swarm intelligence; cooperative strategies for decision making and optimization; advanced networking and security technologies; IT in biomedicine; collective computational intelligence in educational context; science intelligence and data analysis; computational intelligence in financial markets; ensemble learning; big data mining and searching.

Computational Biology of Cancer

Computational Biology of Cancer Book
Author : Dominik Wodarz,Natalia L. Komarova,Natalia Komarova
Publisher : World Scientific Publishing Company Incorporated
Release : 2005
ISBN : 9812560270
Language : En, Es, Fr & De

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Book Description :

- Provides an introduction to computational methods in cancer biology - Follows a multi-disciplinary approach

Emerging Trends in Applications and Infrastructures for Computational Biology Bioinformatics and Systems Biology

Emerging Trends in Applications and Infrastructures for Computational Biology  Bioinformatics  and Systems Biology Book
Author : Hamid R Arabnia,Quoc Nam Tran
Publisher : Morgan Kaufmann
Release : 2016-03-25
ISBN : 0128042591
Language : En, Es, Fr & De

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Book Description :

Emerging Trends in Applications and Infrastructures for Computational Biology, Bioinformatics, and Systems Biology: Systems and Applications covers the latest trends in the field with special emphasis on their applications. The first part covers the major areas of computational biology, development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques for the study of biological and behavioral systems. The second part covers bioinformatics, an interdisciplinary field concerned with methods for storing, retrieving, organizing, and analyzing biological data. The book also explores the software tools used to generate useful biological knowledge. The third part, on systems biology, explores how to obtain, integrate, and analyze complex datasets from multiple experimental sources using interdisciplinary tools and techniques, with the final section focusing on big data and the collection of datasets so large and complex that it becomes difficult to process using conventional database management systems or traditional data processing applications. Explores all the latest advances in this fast-developing field from an applied perspective Provides the only coherent and comprehensive treatment of the subject available Covers the algorithm development, software design, and database applications that have been developed to foster research

Advances in Computational Biology

Advances in Computational Biology Book
Author : Luis F. Castillo,Marco Cristancho,Gustavo Isaza,Andrés Pinzón,Juan Manuel Corchado Rodríguez
Publisher : Springer Science & Business Media
Release : 2013-08-04
ISBN : 3319015680
Language : En, Es, Fr & De

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Book Description :

This volume compiles accepted contributions for the 2nd Edition of the Colombian Computational Biology and Bioinformatics Congress CCBCOL, after a rigorous review process in which 54 papers were accepted for publication from 119 submitted contributions. Bioinformatics and Computational Biology are areas of knowledge that have emerged due to advances that have taken place in the Biological Sciences and its integration with Information Sciences. The expansion of projects involving the study of genomes has led the way in the production of vast amounts of sequence data which needs to be organized, analyzed and stored to understand phenomena associated with living organisms related to their evolution, behavior in different ecosystems, and the development of applications that can be derived from this analysis.

Systems and Computational Biology

Systems and Computational Biology Book
Author : Ning-Sun Yang
Publisher : BoD – Books on Demand
Release : 2011-09-12
ISBN : 9533078758
Language : En, Es, Fr & De

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Book Description :

Whereas some "microarray" or "bioinformatics" scientists among us may have been criticized as doing "cataloging research", the majority of us believe that we are sincerely exploring new scientific and technological systems to benefit human health, human food and animal feed production, and environmental protections. Indeed, we are humbled by the complexity, extent and beauty of cross-talks in various biological systems; on the other hand, we are becoming more educated and are able to start addressing honestly and skillfully the various important issues concerning translational medicine, global agriculture, and the environment. The two volumes of this book present a series of high-quality research or review articles in a timely fashion to this emerging research field of our scientific community.

Emerging Trends in Computational Biology Bioinformatics and Systems Biology

Emerging Trends in Computational Biology  Bioinformatics  and Systems Biology Book
Author : Hamid R Arabnia,Quoc Nam Tran
Publisher : Morgan Kaufmann
Release : 2015-08-11
ISBN : 0128026464
Language : En, Es, Fr & De

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Book Description :

Emerging Trends in Computational Biology, Bioinformatics, and Systems Biology discusses the latest developments in all aspects of computational biology, bioinformatics, and systems biology and the application of data-analytics and algorithms, mathematical modeling, and simu- lation techniques. • Discusses the development and application of data-analytical and theoretical methods, mathematical modeling, and computational simulation techniques to the study of biological and behavioral systems, including applications in cancer research, computational intelligence and drug design, high-performance computing, and biology, as well as cloud and grid computing for the storage and access of big data sets. • Presents a systematic approach for storing, retrieving, organizing, and analyzing biological data using software tools with applications to general principles of DNA/RNA structure, bioinformatics and applications, genomes, protein structure, and modeling and classification, as well as microarray analysis. • Provides a systems biology perspective, including general guidelines and techniques for obtaining, integrating, and analyzing complex data sets from multiple experimental sources using computational tools and software. Topics covered include phenomics, genomics, epigenomics/epigenetics, metabolomics, cell cycle and checkpoint control, and systems biology and vaccination research. • Explains how to effectively harness the power of Big Data tools when data sets are so large and complex that it is difficult to process them using conventional database management systems or traditional data processing applications. Discusses the development and application of data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological and behavioral systems. Presents a systematic approach for storing, retrieving, organizing and analyzing biological data using software tools with applications. Provides a systems biology perspective including general guidelines and techniques for obtaining, integrating and analyzing complex data sets from multiple experimental sources using computational tools and software.

Algorithms for Computational Biology

Algorithms for Computational Biology Book
Author : Adrian-Horia Dediu,Carlos Martín-Vide,Bianca Truthe
Publisher : Springer
Release : 2014-08-05
ISBN : 9783319079523
Language : En, Es, Fr & De

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Book Description :

This book constitutes the refereed proceedings of the First International Conference, AlCoB 2014, held in July 2014 in Tarragona, Spain. The 20 revised full papers were carefully reviewed and selected from 39 submissions. The scope of AlCoB includes topics of either theoretical or applied interest, namely: exact sequence analysis, approximate sequence analysis, pairwise sequence alignment, multiple sequence alignment, sequence assembly, genome rearrangement, regulatory motif finding, phylogeny reconstruction, phylogeny comparison, structure prediction, proteomics: molecular pathways, interaction networks, transcriptomics: splicing variants, isoform inference and quantification, differential analysis, next-generation sequencing: population genomics, metagenomics, metatranscriptomics, microbiome analysis, systems biology.

Methods in Computational Biology

Methods in Computational Biology Book
Author : Ross Carlson,Herbert Sauro
Publisher : MDPI
Release : 2019-07-03
ISBN : 3039211633
Language : En, Es, Fr & De

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Book Description :

Modern biology is rapidly becoming a study of large sets of data. Understanding these data sets is a major challenge for most life sciences, including the medical, environmental, and bioprocess fields. Computational biology approaches are essential for leveraging this ongoing revolution in omics data. A primary goal of this Special Issue, entitled “Methods in Computational Biology”, is the communication of computational biology methods, which can extract biological design principles from complex data sets, described in enough detail to permit the reproduction of the results. This issue integrates interdisciplinary researchers such as biologists, computer scientists, engineers, and mathematicians to advance biological systems analysis. The Special Issue contains the following sections: • Reviews of Computational Methods • Computational Analysis of Biological Dynamics: From Molecular to Cellular to Tissue/Consortia Levels • The Interface of Biotic and Abiotic Processes • Processing of Large Data Sets for Enhanced Analysis • Parameter Optimization and Measurement

Encyclopedia of Bioinformatics and Computational Biology

Encyclopedia of Bioinformatics and Computational Biology Book
Author : Anonim
Publisher : Elsevier
Release : 2018-08-21
ISBN : 0128114320
Language : En, Es, Fr & De

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Book Description :

Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Problem Solving Handbook in Computational Biology and Bioinformatics

Problem Solving Handbook in Computational Biology and Bioinformatics Book
Author : Lenwood S. Heath,Naren Ramakrishnan
Publisher : Springer
Release : 2014-08-15
ISBN : 9781489973481
Language : En, Es, Fr & De

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Book Description :

Bioinformatics is growing by leaps and bounds; theories/algorithms/statistical techniques are constantly evolving. Nevertheless, a core body of algorithmic ideas have emerged and researchers are beginning to adopt a "problem solving" approach to bioinformatics, wherein they use solutions to well-abstracted problems as building blocks to solve larger scope problems. Problem Solving Handbook for Computational Biology and Bioinformatics is an edited volume contributed by world renowned leaders in this field. This comprehensive handbook with problem solving emphasis, covers all relevant areas of computational biology and bioinformatics. Web resources and related themes are highlighted at every opportunity in this central easy-to-read reference. Designed for advanced-level students, researchers and professors in computer science and bioengineering as a reference or secondary text, this handbook is also suitable for professionals working in this industry.