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Clinical Trial Design Challenges In Mood Disorders

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Clinical Trial Design Challenges in Mood Disorders

Clinical Trial Design Challenges in Mood Disorders Book
Author : Mauricio Tohen,Charles Bowden,Andrew A. Nierenberg,John Geddes
Publisher : Academic Press
Release : 2015-01-24
ISBN : 0124051766
Language : En, Es, Fr & De

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Book Description :

Poor clinical trial designs result in failed studies wasting research funds and limiting the advancement of cures for disorders. Clinical Trial Design Challenges in Mood Disorders outlines classic problems researchers face in designing clinical trials and discusses how best to address them for the most definitive and generalizable results. Traditional trial designs are included as well as novel analytic techniques. The book examines information on high placebo response, the generalizability of studies conducted in the developing world, the duration of maintenance studies, and the application of findings into clinical practice. With representation from contributors throughout the world and from academia, industry, regulatory agencies, and advocacy groups, this book will contribute toward improved clinical trial design and valid, precise, and reliable answers about what works better and faster for patients. Summarizes common trial design problems and their solutions Encompasses funding, subject selection, regulatory issues and more Identifies best practices for definitive and generalizable results Includes traditional trial designs and novel analytic techniques Represents academia, industry, regulatory agencies, and advocacy groups

Committee Staff Report to the Chairman and Ranking Member

Committee Staff Report to the Chairman and Ranking Member Book
Author : Anonim
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Committee Staff Report to the Chairman and Ranking Member book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Psychopharmacology Bulletin

Psychopharmacology Bulletin Book
Author : Anonim
Publisher : Unknown
Release : 1990
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Psychopharmacology Bulletin book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Bipolar Disorders

Bipolar Disorders Book
Author : Andreas Marneros,Frederick Goodwin
Publisher : Cambridge University Press
Release : 2005-10-06
ISBN : 9781139445771
Language : En, Es, Fr & De

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Book Description :

Bipolar disorder manifests itself in a variety of forms. It can coexist with other psychiatric conditions, and treatment efficacy can depend on the type of bipolar state. This book covers the full range of atypical, rapid cycling and transient forms of bipolar disorder, from atypical and agitated depression to schizoaffective mixed states. The most recent ICD category is covered, and the authors also look at the biology and genetics of bipolar disorder, along with issues relating to age (children and the elderly), comorbidity, choice of drug treatment and investigational strategies.

Wiley Encyclopedia of Clinical Trials

Wiley Encyclopedia of Clinical Trials Book
Author : Lisa Marie Sullivan,Joseph Massaro
Publisher : Wiley-Interscience
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Here you'll find more than 500 entries from the world's leading experts in the field on the basic concepts, methodologies, and applications in clinical trials. The range of topics includes: basic statistical concepts, design and analysis of clinical trials, ethics, regulatory issues, and methodologies for clinical data management and analysis

GABA and Mood Disorders

GABA and Mood Disorders Book
Author : Giuseppe Bartholini,K. G. Lloyd,Paolo Lucio Morselli
Publisher : Unknown
Release : 1986
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download GABA and Mood Disorders book written by Giuseppe Bartholini,K. G. Lloyd,Paolo Lucio Morselli, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Current and Emerging Issues in Cancer Pain

Current and Emerging Issues in Cancer Pain Book
Author : C. Richard Chapman,Kathleen M. Foley
Publisher : Raven Press (ID)
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

(Sympos. Seattle 7/92) Covers depression in the cancer patient emotional aspect of pain ethical issues etc.

Pharmacotherapy for Mood Anxiety and Cognitive Disorders

Pharmacotherapy for Mood  Anxiety  and Cognitive Disorders Book
Author : Uriel Halbreich,S. A. Montgomery
Publisher : American Psychiatric Pub
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This book takes a critical look at the medications available for treating mood, anxiety, and cognitive disorders; their relevance to pathobiology and underlying mechanisms; and their limitations. The contributors provide background and rationale in understanding the underlying mechanisms of frontline treatments for these disorders.

Research Publications Association for Research in Nervous and Mental Disease

Research Publications   Association for Research in Nervous and Mental Disease Book
Author : Association for Research in Nervous and Mental Disease
Publisher : Unknown
Release : 1985
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Research Publications Association for Research in Nervous and Mental Disease book written by Association for Research in Nervous and Mental Disease, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Psychological Abstracts

Psychological Abstracts Book
Author : Walter Samuel Hunter
Publisher : Unknown
Release : 1999
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Psychological Abstracts book written by Walter Samuel Hunter, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

An Anthology of Psychiatric Ethics

An Anthology of Psychiatric Ethics Book
Author : Stephen A. Green,Sidney Bloch
Publisher : Oxford University Press, USA
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This title includes the following features: Presents a comprehensivediscussion of the central issues of psychiatric ethics, defining and exploringeach of these issues; Contains essential readings for each of these central issues, providing in onevolume readings that would otherwise be difficult to obtain; Includes introductory essays that provide a comprehensive overview of eachissue, efficiently and effectively organizing the reader's approach to theselected readings; Draws on the success of the well-known and respected 'PsychiatricEthics'

Proceedings in Print

Proceedings in Print Book
Author : Anonim
Publisher : Unknown
Release : 1995
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Proceedings in Print book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Clinical Handbook for the Management of Mood Disorders

Clinical Handbook for the Management of Mood Disorders Book
Author : J. John Mann
Publisher : Cambridge University Press
Release : 2013-05-09
ISBN : 1107067448
Language : En, Es, Fr & De

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Book Description :

This Clinical Handbook for the Management of Mood Disorders will equip clinicians with the knowledge to refine their diagnostic skills and implement treatment plans for mood disorders based on the most up-to-date evidence on interventions that work. Covering the widest range of treatments and techniques, it provides clear guidance for the management of all types and subtypes of both minor and major depression. Chapters cover the latest and most innovative treatments, including use of ketamine, deep brain stimulation and transcranial magnetic stimulation, effective integration of pharmacological and psychotherapeutic approaches, as well as providing a thought-provoking look at the future research agenda and the potential for reliable biomarkers. This is the most comprehensive review of depression available today. Written and edited by leading experts mostly from Columbia University, this is an essential resource for anyone involved in the care and treatment of patients with mood disorders.

Clinical Guide to Depression and Bipolar Disorder

Clinical Guide to Depression and Bipolar Disorder Book
Author : Martin B. Keller,William H. Coryell,Jean Endicott,Jack D. Maser,Pamela J. Schettler
Publisher : American Psychiatric Pub
Release : 2013-04-10
ISBN : 1585629944
Language : En, Es, Fr & De

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Book Description :

Conceived in the early 1970s to study the phenomenology, diagnosis, genetics, and clinical course of depression, the NIMH Collaborative Depression Study (CDS) has influenced research and practice since its inception. Clinical Guide to Depression and Bipolar Disorder: Findings From the Collaborative Depression Study summarizes key findings from the study and the related literature to provide comprehensive and up-to-date knowledge on the course and outcome of illness in mood disorders. Nowhere else can clinicians find such detailed longitudinal data, combined with astute clinical analysis of the current research. The volume offers: Historical background on how psychodynamic psychiatry was overtaken by psychobiological perspectives, and the challenges and controversies that gave rise to the CDS, providing the context necessary to understand the profession's development to the present day. A wealth of information on nosology, natural history, phenomenology, and treatment response in depressive and bipolar disorders. Detailed descriptions of the study methods employed, providing information and insights that will assist researchers in the longitudinal design of prospective cohort studies. Comprehensive review of outcomes in mood disorder, including delineation of the long-term course of bipolar I, bipolar II, and unipolar major depressive disorders, the implications of which will continue to be instrumental in the development of psychiatric nosology and indispensable to clinicians engaged in assessment and treatment. Critical information clinicians need in order to read the clinical signs in their patients and predict the "switch" from unipolar to bipolar disorder. A fascinating review of the evolution of diagnostic thinking about the role of anxiety in mood disorders, and the contributions of the CDS to the newly published DSM-5®. Each chapter is accompanied by a time-saving summary, as well as a section on clinical implications that translates the findings into practical points and key recommendations clinicians need to know to provide optimal care. Psychiatrists, clinical psychologists, residents, and fellows will turn to Clinical Guide to Depression and Bipolar Disorder: Findings From the Collaborative Depression Study to better understand the course and outcome of their patients' mood disorders and, ultimately, to improve their clinical skills.

Defining Psychopathology in the 21st Century

Defining Psychopathology in the 21st Century Book
Author : American Psychopathological Association
Publisher : American Psychiatric Pub
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This volume is divided into four sections: definitional tensions, imaging psychopathology, longitudinal studies, and exploring alternatives. It represents a significant step in developing approaches to classification that will lead to more accurate diagnoses and treatments for patients and a broader range of taxonomic options for researchers.

Disorders of Mood

Disorders of Mood Book
Author : American Psychopathological Association. Meeting,American Psychopathological Association
Publisher : Johns Hopkins University Press
Release : 1972
ISBN : 9780801812972
Language : En, Es, Fr & De

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Book Description :

Download Disorders of Mood book written by American Psychopathological Association. Meeting,American Psychopathological Association, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Optimizing the Devlopment of Antipsychotic Drugs

Optimizing the Devlopment of Antipsychotic Drugs Book
Author : John J. Sramek,Neal R. Cutler,Neil M. Kurtz,Michael F. Murphy,Angelico Carta
Publisher : John Wiley & Sons Incorporated
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The interest in developing novel antipsychotics is especially keen at this time and this book presents the latest information in that development. Numerous compounds are in the preclinical and clinical pipeline. The pharmaceutical industry, as well as psychiatrists, clinicians, mental health professionals and anyone else interested in the design and conduct of clinical trials of schizophrenia, are waiting for these research results. Revealing recommendations for developing antipsychotic compounds based on the extensive experience of the authors, this work will provide long-awaited information on a previously unexplored area.

Drug Intelligence Clinical Pharmacy

Drug Intelligence   Clinical Pharmacy Book
Author : Anonim
Publisher : Unknown
Release : 1988
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Drug Intelligence Clinical Pharmacy book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Journal of the American Medical Women s Association

Journal of the American Medical Women s Association Book
Author : American Medical Women's Association
Publisher : Unknown
Release : 1994
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Journal of the American Medical Women s Association book written by American Medical Women's Association, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Bipolar Depression

Bipolar Depression Book
Author : Rif S. El-Mallakh,S. Nassir Ghaemi
Publisher : American Psychiatric Pub
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Discusses and assesses various treatments for bipolar depression.