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Clinical Molecular Medicine

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Clinical Molecular Medicine

Clinical Molecular Medicine Book
Author : Dhavendra Kumar
Publisher : Academic Press
Release : 2019-11-30
ISBN : 0128094427
Language : En, Es, Fr & De

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Book Description :

Clinical Molecular Medicine: Principles and Practice presents the latest scientific advances in molecular and cellular biology, including the development of new and effective drug and biological therapies and diagnostic methods. The book provides medical and biomedical students and researchers with a clear and clinically relevant understanding on the molecular basis of human disease. With an increased focus on new practice concepts, such as stratified, personalized and precision medicine, this book is a valuable and much-needed resource that unites the core principles of molecular biology with the latest and most promising genomic advances. Illustrates the fundamental principles and therapeutic applications of molecular and cellular biology Offers a clinically focused account of molecular heterogeneity Includes comprehensive coverage of many different disorders, including growth and development, cardiovascular, metabolic, skin, blood, digestive, inflammatory, neuropsychiatric disorders, and many more

Modern Clinical Molecular Techniques

Modern Clinical Molecular Techniques Book
Author : Peter Hu,Madhuri Hegde,Patrick Alan Lennon
Publisher : Springer Science & Business Media
Release : 2012-05-11
ISBN : 1461421705
Language : En, Es, Fr & De

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Book Description :

This timely book covers the need to know clinical practices for all those involved in molecular laboratory science. The field of molecular medicine is evolving at an astounding speed. Propelled by the new insights and technologies, advances are being made at an unprecedented rate. With dual measure given to today’s breakthroughs, this book is a collection of the most current practices relevant to the clinical molecular laboratorian. It begins with an introductory section on techniques and procedure. It then presents four separate sections on infectious disease, oncology, pre/post-natal, and identity testing, with specific chapters clearly outlining clinical protocols used in daily practice. Modern Clinical Molecular Techniques cuts to the heart of what is essential for the practicing molecular laboratory scientist. It is an outstanding resource for those operating within or looking to set up a clinical molecular laboratory.

Principles of Molecular Medicine

Principles of Molecular Medicine Book
Author : Marschall S. Runge,Cam Patterson
Publisher : Springer Science & Business Media
Release : 2007-11-18
ISBN : 159259963X
Language : En, Es, Fr & De

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Book Description :

The concept of molecular medicine dates back to Linus means that there are many new opportunities and challenges Pauling, who in the late 1940s and early 1950s generalized for clinical medicine. One of the effects of the completion of from the ideas that came from the study of the sickle cell the Human Genome Project is the increasing application of hemoglobin molecule. With the first cloning of human genes the fields of molecular biology and genetics to the und- about 1976, molecular genetics took the molecular perspec- standing and management of common diseases. Assimi- tive on disease to the level of DNA. The term molecular tion of the new developments since the first edition has been medicine achieved wide currency in the 1980s with the ably accomplished by Drs. Runge and Patterson with the assignment of this designation to journals, at least one soci- help of their many knowledgeable authors. ety, institutes, and academic divisions of departments of in- As was evident in the first edition, molecular genetics is ternal medicine. Undoubtedly, molecular medicine has been involved in every specialty of medicine. A recurrent theme abetted by the Human Genome Project, which has aided in that edition, perhaps even more striking in the present one, greatly in the molecular characterization of disease.

Science In Medicine

Science In Medicine Book
Author : American Society for Clinical Investigation,
Publisher : Jones & Bartlett Learning
Release : 2007-10-31
ISBN : 9780763750831
Language : En, Es, Fr & De

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Book Description :

Science in Medicine: The JCI Textbook of Molecular Medicine is a collection of acclaimed articles published in the Journal of Clinical Investigation during the Journal’s tenure at Columbia University. The society that publishes the JCI, the American Society for Clinical Investigation (ASCI), is an honor society of physician scientists, representing those who are at the forefront of translating findings in the laboratory to the advancement of clinical practice. This textbook brings together state-of-the-art reviews written by the world's leading authorities, including many ASCI members. The reviews examine the molecular mechanisms underlying a wide array of diseases and disorders affecting all major organ systems. The fundamentals of the organ or physiological systems in question are present alongside the underlying genetic or physiological abnormalities that result in disease. This text illustrates the translation of basic scientific knowledge into the current practice of clinical medicine. The reviews provide an authoritative and comprehensive overview by building on known scientific concepts and treatment of human disease while exploring where these advances might take medicine over the next decade. The book is a valuable resource for medical students, graduate students, house staff, attending and practicing physicians, and biomedical researchers.

Self assessment Questions for Clinical Molecular Genetics

Self assessment Questions for Clinical Molecular Genetics Book
Author : Haiying Meng
Publisher : Academic Press
Release : 2019-05-28
ISBN : 0128099682
Language : En, Es, Fr & De

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Book Description :

Review Questions of Clinical Molecular Genetics presents a comprehensive study guide for the board and certificate exams presented by the American College of Medical Genetics and Genomics (ACMG) and the American Board of Medical Genetics and Genomics (ABMGG). It provides residents and fellows in genetics and genomics with over 1,000 concise questions, ranging from topics in cystic fibrosis, to genetic counseling, to trinucleotide repeat expansion disorders. It puts key points in the form of questions, thus challenging the reader to retain knowledge. As board and certificate exams require knowledge of new technologies and applications, this book helps users meet that challenge. Includes over 1,0000 multiple-choice, USMLE style questions to help readers prepare for specialty exams in Clinical Cytogenetics and Clinical Molecular Genetics Designed to assist clinical molecular genetic fellows, genetic counselors, medical genetic residents and fellows, and molecular pathologist residents in preparing for their certification exam Assists trainees on how to follow guidelines and put them in practice

Molecular Medicine

Molecular Medicine Book
Author : Jens Kurreck,Cy Aaron Stein
Publisher : John Wiley & Sons
Release : 2016-02-16
ISBN : 3527331891
Language : En, Es, Fr & De

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Book Description :

Easy to read, yet comprehensive, this is the perfect introduction into the molecular basis of disease and the novel treatment options that have become available. The authors, Jens Kurreck and Cy Stein, have both long-standing teaching experience on the subject, one from a biologist's angle, the other with a medical background. Together, they have produced a modern textbook for courses in Molecular Medicine that incorporates modules from immunology to signaling, from virology to gene therapy, and the latest development in personalized medicine.

Introduction to Molecular Medicine

Introduction to Molecular Medicine Book
Author : Dennis W. Ross
Publisher : Springer Science & Business Media
Release : 2013-03-09
ISBN : 147574076X
Language : En, Es, Fr & De

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Book Description :

How will increased understanding of the human genome affect our ability to diagnose and treat disease? The subject of recombinant DNA technology is no longer limited to the research laboratory; it is being discussed in ever-widening medical circles. Introduction to Molecular Medicine is especially written for the physician who is not a genetics expert but wishes to understand this new science and find entry to the more specialized publications. The first chapters present the basic concepts of the human genome and gene regulation. Subsequent chapters consider how today's new approach can be applied in areas such as forensic medicine, transplantation medicine, drug manufacture and genetic engineering. For example, a major section on cancer explores the diagnosis of leukemia and lymphoma through the detection of gene rearrangement and oncongeny mutation. One feature that will especially interest pathologists, pediatricians and residents is the discussion of diagnostic tests that are used in current practice.

Principles of Molecular Medicine

Principles of Molecular Medicine Book
Author : J. Larry Jameson
Publisher : Springer Science & Business Media
Release : 1998-07-13
ISBN : 1592597262
Language : En, Es, Fr & De

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Book Description :

Within the framework of clinical internal medicine, they will gain critical knowledge of the many powerful molecular biology-based developments now so rapidly enhancing our understanding of the pathophysiology of disease, improving the feasibility and accuracy of diagnostic testing, and opening novel therapeutic avenues, including gene therapy. Readers will also gain a fuller understanding of the role played by genetic defects in a host of diseases, among them peripheral neuropathies, Alzheimer's disease, arrhythmias, leukemias and lymphomas, cystic fibrosis, hepatitis, HIV, autoimmune disorders, polycystic kidney disease, schizophrenia, affective disorders, alcoholism, Huntington's disease, and many more.

Molecular Genetic Pathology

Molecular Genetic Pathology Book
Author : Liang Cheng,David Y. Zhang
Publisher : Springer Science & Business Media
Release : 2010-01-01
ISBN : 9781597454056
Language : En, Es, Fr & De

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Book Description :

This volume presents a useful and up-to-date handbook containing information relevant to the clinical practice of molecular genetic pathology. It features organized, detailed text on specific molecular genetic techniques. The volume provides a unique reference for the practicing pathologist and medical geneticist, as well as a review book for residents and fellows in training in pathology, medical genetics and molecular genetic pathology.

Molecular Medicine

Molecular Medicine Book
Author : R.J. Trent
Publisher : Academic Press
Release : 2005-05-13
ISBN : 9780126990577
Language : En, Es, Fr & De

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Book Description :

Molecular medicine is the application of gene or DNA based knowledge to the modern practice of medicine. This book provides contemporary insights into how the genetic revolution is influencing medical thinking and practice on a broad front including clinical medicine, innovative therapies and forensic medicine. Extensively revised just after the completion of the Human Genome Project, it provides the latest in molecular medicine developments The only book in Molecular Medicine that has undergone three editions Current practice as well as future developments identified Extensive tables, well presented figures - resources for further understanding

Lecture Notes on Molecular Medicine

Lecture Notes on Molecular Medicine Book
Author : John R. Bradley,David Johnson,David Rubenstein
Publisher : Wiley-Blackwell
Release : 2001-10-18
ISBN : 9780632058396
Language : En, Es, Fr & De

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Book Description :

Lecture Notes on Molecular Medicine provides a concise and straightforward introduction to molecular biology, explaining how it is used to understand and treat human disease. This new edition has been written in response to exciting changes in this fast-moving field. Fully updated, it explains the human genome project and how the sequence will change medicine. It also covers many new methods that have been introduced since the first edition was published. Beginning with first principles, the book is a useful primer for any science student new to molecular biology and genetics. It is also an invaluable resource for medical students and practicing doctors who need an understanding of how advances in molecular biology have impacted clinical medicine, especially in the fields of gene therapy and screening. For ease of use Lecture Notes on Molecular Medicine is divided into four sections: Basic Principles: describing the fundamentals of DNA structure and function that underpin molecular biology Biomolecular Tools: covering the manipulation of DNA and RNA and molecular techniques. Understanding Genetics: covering the basic principles of inheritance, biodiversity, gene mapping and expression and gene therapy. Molecular Medicine in Practice: discussing the profound effect which molecular biology has had on medical practice at all levels. This chapter has been greatly expanded in this new edition to cover all the latest developments in the field. A concise introduction to the basic principles & applications of molecular medicine. Explains complicated science in simple terms with clear diagrams. Integrates basic and clinical science by emphasising application to clinical medicine. Expanded chapter examining molecular medicine in clinical practice.

Molecular Pathology in Clinical Practice

Molecular Pathology in Clinical Practice Book
Author : Debra G.B. Leonard
Publisher : Springer
Release : 2016-02-02
ISBN : 331919674X
Language : En, Es, Fr & De

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Book Description :

This authoritative textbook offers in-depth coverage of all aspects of molecular pathology practice and embodies the current standard in molecular testing. Since the successful first edition, new sections have been added on pharmacogenetics and genomics, while other sections have been revised and updated to reflect the rapid advances in the field. The result is a superb reference that encompasses molecular biology basics, genetics, inherited cancers, solid tumors, neoplastic hematopathology, infectious diseases, identity testing, HLA typing, laboratory management, genomics and proteomics. Throughout the text, emphasis is placed on the molecular variations being detected, the clinical usefulness of the tests and important clinical and laboratory issues. The second edition of Molecular Pathology in Clinical Practice will be an invaluable source of information for all practicing molecular pathologists and will also be of utility for other pathologists, clinical colleagues and trainees.

Advances in Molecular Pathology E Book 2019

Advances in Molecular Pathology  E Book 2019 Book
Author : Gregory J. Tsongalis
Publisher : Elsevier Health Sciences
Release : 2019-11-06
ISBN : 0323709516
Language : En, Es, Fr & De

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Book Description :

This issue of Advances in Molecular Pathology will provide a comprehensive review of the most current practices, trends, and developments in the field of Molecular Pathology. Publishing on an annual basis, the volume will be divided into 7 sections: Genetics, Hematopathology, Infectious Disease, Pharmacogenomics, Informatics, Solid tumors, and Identity/HLA. Led by Dr. Gregory Tsongalis of Dartmouth University, a team of experienced pathologists from institutions across the country oversee annual topic and expert author selection.

Molecular Medical Microbiology

Molecular Medical Microbiology Book
Author : Yi-Wei Tang,Max Sussman,Dongyou Liu,Ian Poxton,Joseph Schwartzman
Publisher : Academic Press
Release : 2014-09-14
ISBN : 0123977630
Language : En, Es, Fr & De

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Book Description :

The molecular age has brought about dramatic changes in medical microbiology, and great leaps in our understanding of the mechanisms of infectious disease. Molecular Medical Microbiology is the first book to synthesise the many new developments in both molecular and clinical research in a single comprehensive resource. This timely and authoritative three-volume work is an invaluable reference source of medical bacteriology. Comprising more than 100 chapters, organized into 17 major sections, the scope of this impressive work is wide-ranging. Written by experts in the field, chapters include cutting-edge information, and clinical overviews for each major bacterial group, in addition to the latest updates on vaccine development, molecular technology and diagnostic technology. Topics covered include bacterial structure, cell function, and genetics; mechanisms of pathogenesis and prevention; antibacterial agents; and infections ranging from gastrointestinal to urinary tract, centrtal nervous system, respiratory tract, and more. The first comprehensive and accessible reference on molecular medical microbiology Full color presentation througout In-depth discussion of individual pathogenic bacteria in a system-oriented approach Includes a clinical overview for each major bacterial group Presents the latest information on vaccine development, molecular technology, and diagnostic technology More than 100 chapters covering all major groups of bacteria Written by an international panel of authors who are experts in their respective disciplines

An Introduction to Molecular Medicine and Gene Therapy

An Introduction to Molecular Medicine and Gene Therapy Book
Author : Thomas F. Kresina
Publisher : John Wiley & Sons
Release : 2004-04-07
ISBN : 0471461040
Language : En, Es, Fr & De

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Book Description :

Gene therapy, or the use of genetic manipulation for diseasetreatment, is derived from advances in genetics, molecular biology,clinical medicine, and human genomics. Molecular medicine, theapplication of molecular biological techniques to disease treatmentand diagnosis, is derived from the development of human organtransplantation, pharmacotherapy, and elucidation of the humangenome. An Introduction to Molecular Medicine and GeneTherapy provides a basis for interpreting new clinical andbasic research findings in the areas of cloning, gene transfer, andtargeting; the applications of genetic medicine to clinicalconditions; ethics and governmental regulations; and the burgeoningfields of genomics, biotechnology, and bioinformatics. By dividingthe material into three sections - an introduction to basicscience, a review of clinical applications, and a discussion of theevolving issues related to gene therapy and molecular medicine-thiscomprehensive manual describes the basic approaches to the broadrange of actual and potential genetic-based therapies. In addition, An Introduction to Molecular Medicine andGene Therapy: Covers new frontiers in gene therapy, animal models, vectors,gene targeting, and ethical/legal considerations Provides organ-based reviews of current studies in gene therapyfor monogenetic, multifactoral or polygenic disorders, andinfectious diseases Includes bold-faced terms, key concepts, summaries, and listsof helpful references by subject in each chapter Contains appendices on commercial implications and a review ofthe history of gene therapy This textbook offers a clear, concise writing style, drawingupon the expertise of the authors, all renowned researchers intheir respective specialties of molecular medicine. Researchers ingenetics and molecular medicine will all find An Introductionto Molecular Medicine and Gene Therapy to be an essentialguide to the rapidly evolving field of gene therapy and itsapplications in molecular medicine.

Clinical Science and Molecular Medicine

Clinical Science and Molecular Medicine Book
Author : Anonim
Publisher : Unknown
Release : 1974
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Includes Abstracts of the Medical Research Society and of the Society's Annual Guest Lectures.

Molecular Medical Biochemistry

Molecular Medical Biochemistry Book
Author : J. P. Luzio,R. J. Thompson
Publisher : Cambridge University Press
Release : 1990-02-22
ISBN : 9780521278287
Language : En, Es, Fr & De

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Book Description :

The many exciting developments in cell and molecular biology in recent years have important implications for the practice of medicine. The purpose of this new text is to bring these developments to the attention of undergraduates taking courses in biochemistry. The emphasis is on topics (membrane structure and function, hormone action and secretion) where current knowledge of macromolecular and cellular structure and function is likely to contribute most to understanding the underlying pathology of common multifactorial diseases. The book also outlines the basic features of recombinant DNA techniques and the impact they are having in the diagnosis, treatment and knowledge of disease processes.

Molecular Diagnostics

Molecular Diagnostics Book
Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Springer Science & Business Media
Release : 2007-10-28
ISBN : 1592599281
Language : En, Es, Fr & De

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Book Description :

Accompanying CD-ROM contains ... "a companion eBook version of Molecular diagnostics : for the clinical laboratorian, Second edition ... for downloading and use in the reader's PC or PDA." -- p. [4] of cover.

Essential Concepts in Molecular Pathology

Essential Concepts in Molecular Pathology Book
Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Release : 2010-02-16
ISBN : 9780080922188
Language : En, Es, Fr & De

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Book Description :

This streamlined "essential" version of the Molecular Pathology (2009) textbook extracts key information, illustrations and photographs from the main textbook in the same number and organization of chapters. It is aimed at teaching students in courses where the full textbook is not needed, but the concepts included are desirable (such as graduate students in allied health programs or undergraduates). It is also aimed at students who are enrolled in courses that primarily use a traditional pathology textbook, but need the complementary concepts of molecular pathology (such as medical students). Further, the textbook will be valuable for pathology residents and other postdoctoral fellows who desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. Offers an essential introduction to molecular genetics and the "molecular" aspects of human disease Teaches from the perspective of "integrative systems biology," which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease In-depth presentation of the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease using histopathology. "Traditional" pathology section provides state-of-the-art information on the major forms of disease, their pathologies, and the molecular mechanisms that drive these diseases. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology: molecular diagnostics, molecular assessment, and personalized medicine Each chapter ends with Key Summary Points and Suggested Readings

Molecular Medicine for Clinicians

Molecular Medicine for Clinicians Book
Author : Barry Mendelow,Nanthakumarn Chetty
Publisher : Wits University Press
Release : 2008-01-01
ISBN : 1868144658
Language : En, Es, Fr & De

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Book Description :

An introductory text for medical registrars about molecular medicine in South Africa The insights following the wake of the Human Genome project are radically influencing our understanding of the molecular basis of life, health and disease. The improved accuracy and precision of clinical diagnostics is also beginning to have an impact on therapeutics in a fundamental way. This book is suitable for undergraduate medical students, as part of their basic sciences training, but is also relevant to interested under- and postgraduate science and engineering students. It serves as an introductory text for medical registrars in virtually all specialties, and is also of value to the General Practitioner wishing to keep up to date, especially in view of the growing, internet-assisted public knowledge of the field. There is a special focus on the application of molecular medicine in Africa and in developing countries elsewhere.