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Clinical Engineering Handbook

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Clinical Engineering Handbook

Clinical Engineering Handbook Book
Author : Ernesto Iadanza
Publisher : Academic Press
Release : 2019-12-06
ISBN : 0128134682
Language : En, Es, Fr & De

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Book Description :

Clinical Engineering Handbook, Second Edition, covers modern clinical engineering topics, giving experienced professionals the necessary skills and knowledge for this fast-evolving field. Featuring insights from leading international experts, this book presents traditional practices, such as healthcare technology management, medical device service, and technology application. In addition, readers will find valuable information on the newest research and groundbreaking developments in clinical engineering, such as health technology assessment, disaster preparedness, decision support systems, mobile medicine, and prospects and guidelines on the future of clinical engineering. As the biomedical engineering field expands throughout the world, clinical engineers play an increasingly important role as translators between the medical, engineering and business professions. In addition, they influence procedures and policies at research facilities, universities, and in private and government agencies. This book explores their current and continuing reach and its importance. Presents a definitive, comprehensive, and up-to-date resource on clinical engineering Written by worldwide experts with ties to IFMBE, IUPESM, Global CE Advisory Board, IEEE, ACCE, and more Includes coverage of new topics, such as Health Technology Assessment (HTA), Decision Support Systems (DSS), Mobile Apps, Success Stories in Clinical Engineering, and Human Factors Engineering

Clinical Engineering Handbook

Clinical Engineering Handbook Book
Author : Joseph F. Dyro
Publisher : Academic Press
Release : 2004
ISBN : 012226570X
Language : En, Es, Fr & De

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Book Description :

Author Joseph Dyro has been awarded the Association for the Advancement of Medical Instrumentation (AAMI) Clinical/Biomedical Engineering Achievement Award which recognizes individual excellence and achievement in the clinical engineering and biomedical engineering fields. He has also been awarded the American College of Clinical Engineering 2005 Tom O'Dea Advocacy Award. As the biomedical engineering field expands throughout the world, clinical engineers play an evermore important role as the translator between the worlds of the medical, engineering, and business professionals. They influence procedure and policy at research facilities, universities and private and government agencies including the Food and Drug Administration and the World Health Organization. Clinical Engineers were key players in calming the hysteria over electrical safety in the 1970's and Y2K at the turn of the century and continue to work for medical safety. This title brings together all the important aspects of Clinical Engineering. It provides the reader with prospects for the future of clinical engineering as well as guidelines and standards for best practice around the world. * Clinical Engineers are the safety and quality faciltators in all medical facilities.

Clinical Engineering

Clinical Engineering Book
Author : Azzam Taktak,Paul Ganney,David Long,Richard Axell
Publisher : Academic Press
Release : 2019-12-01
ISBN : 0081026951
Language : En, Es, Fr & De

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Book Description :

Clinical Engineering: A Handbook for Clinical and Biomedical Engineers, Second Edition, helps professionals and students in clinical engineering successfully deploy medical technologies. The book provides a broad reference to the core elements of the subject, drawing from a range of experienced authors. In addition to engineering skills, clinical engineers must be able to work with both patients and a range of professional staff, including technicians, clinicians and equipment manufacturers. This book will not only help users keep up-to-date on the fast-moving scientific and medical research in the field, but also help them develop laboratory, design, workshop and management skills. The updated edition features the latest fundamentals of medical technology integration, patient safety, risk assessment and assistive technology. Provides engineers in core medical disciplines and related fields with the skills and knowledge to successfully collaborate on the development of medical devices, via approved procedures and standards Covers US and EU standards (FDA and MDD, respectively, plus related ISO requirements) Includes information that is backed up with real-life clinical examples, case studies, and separate tutorials for training and class use Completely updated to include new standards and regulations, as well as new case studies and illustrations

Introduction to Clinical Engineering

Introduction to Clinical Engineering Book
Author : Samantha Jacques,Barbara Christe
Publisher : Academic Press
Release : 2020-08-06
ISBN : 0128181044
Language : En, Es, Fr & De

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Book Description :

Introduction to Clinical Engineering focuses on the application of engineering practice within the healthcare delivery system, often defined as clinical engineering. Readers will explore the fundamental concepts integral to the support of healthcare technology to advance medical care. The primary mission of clinical engineers is the utilization of medical devices, software, and systems to deliver safe and effective patient care throughout technology’s lifecycle. This unique and interdisciplinary workforce is part of the healthcare team and serves as the intersection between engineering and medicine. This book is aimed at practitioners, managers, students, and educators to serve as a resource that offers a broad perspective of the applications of engineering principles, regulatory compliance, lifecycle planning, systems thinking, risk analysis, and resource management in healthcare. This book is an invaluable tool for healthcare technology management (HTM) professionals and can serve as a guide for students to explore the profession in depth. Offers readers an in-depth look into the support and implementation of existing medical technology used for patient care in a clinical setting Provides insights into the clinical engineering profession, focusing on engineering principles as applied to the US healthcare system Explores healthcare technology, hospital and systems safety, information technology and interoperability with medical devices, clinical facilities management, as well as human resource management

Handbook of Biomedical Engineering

Handbook of Biomedical Engineering Book
Author : Jacob Kline
Publisher : Elsevier
Release : 2012-12-02
ISBN : 0323142680
Language : En, Es, Fr & De

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Book Description :

Handbook of Biomedical Engineering covers the most important used systems and materials in biomedical engineering. This book is organized into six parts: Biomedical Instrumentation and Devices, Medical Imaging, Computers in Medicine, Biomaterials and Biomechanics, Clinical Engineering, and Engineering in Physiological Systems Analysis. These parts encompassing 27 chapters cover the basic principles, design data and criteria, and applications and their medical and/or biological relationships. Part I deals with the principles, mode of operation, and uses of various biomedical instruments and devices, including transducers, electrocardiograph, implantable electrical devices, biotelemetry, patient monitoring systems, hearing aids, and implantable insulin delivery systems. Parts II and III describe the basic principle of medical imaging devices and the application of computers in medicine, particularly in the fields of data management, critical care, clinical laboratory, radiology, artificial intelligence, and research. Part IV focuses on the application of biomaterials and biomechanics in orthopedic and accident investigation, while Part V considers the major functions of clinical engineering. Part VI provides the principles and application of mathematical models in physiological systems analysis. This book is valuable as a general reference for courses in a biomedical engineering curriculum.

The Engineering Handbook of Smart Technology for Aging Disability and Independence

The Engineering Handbook of Smart Technology for Aging  Disability  and Independence Book
Author : Abdelsalam Helal,Mounir Mokhtari,Bessam Abdulrazak
Publisher : John Wiley & Sons
Release : 2008-09-22
ISBN : 0470379359
Language : En, Es, Fr & De

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Book Description :

An advanced look at smart technology to promote the independence of the elderly and disabled Ongoing research and advancements in technology are essential for the continuing independence of elderly and disabled persons. The Engineering Handbook of Smart Technology for Aging, Disability, and Independence provides a thorough analysis of these technologies and the needs of the elderly and disabled, including a breakdown of demographics, government spending, growth rate, and much more. Each chapter is written by an expert in his or her respective field, and gives readers unparalleled insight into the research and developments in a multitude of important areas, including: User-need analyses, classifications, and policies Assistive devices and systems for people with motor disabilities Assistive devices and systems for people with visual and hearing impairments Human-machine interaction and virtual reality Assistive robotics Technology for user mobility and object manipulation Smart homes as assistant environments A discussion of emerging standards and guidelines to build accessible devices, tools, and environments This book is an indispensable resource for researchers and professionals in computer science, rehabilitation science, and clinical engineering. It also serves as a valuable textbook for graduate students in the aforementioned fields.

Handbook of Data Science Approaches for Biomedical Engineering

Handbook of Data Science Approaches for Biomedical Engineering Book
Author : Valentina Emilia Balas,Vijender Kumar Solanki,Raghvendra Kumar,Manju Khari
Publisher : Academic Press
Release : 2019-11-13
ISBN : 0128183195
Language : En, Es, Fr & De

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Book Description :

Handbook of Data Science Approaches for Biomedical Engineering covers the research issues and concepts of biomedical engineering progress and the ways they are aligning with the latest technologies in IoT and big data. In addition, the book includes various real-time/offline medical applications that directly or indirectly rely on medical and information technology. Case studies in the field of medical science, i.e., biomedical engineering, computer science, information security, and interdisciplinary tools, along with modern tools and the technologies used are also included to enhance understanding. Today, the role of Big Data and IoT proves that ninety percent of data currently available has been generated in the last couple of years, with rapid increases happening every day. The reason for this growth is increasing in communication through electronic devices, sensors, web logs, global positioning system (GPS) data, mobile data, IoT, etc. Provides in-depth information about Biomedical Engineering with Big Data and Internet of Things Includes technical approaches for solving real-time healthcare problems and practical solutions through case studies in Big Data and Internet of Things Discusses big data applications for healthcare management, such as predictive analytics and forecasting, big data integration for medical data, algorithms and techniques to speed up the analysis of big medical data, and more

Clinical Engineering

Clinical Engineering Book
Author : Yadin David,Wolf W. von Maltzahn,Michael R. Neuman,Joseph D. Bronzino
Publisher : CRC Press
Release : 2003-03-26
ISBN : 0203009177
Language : En, Es, Fr & De

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Book Description :

A volume in the Principles and Applications in Engineering series, Clinical Engineering focuses on managing the deployment of medical technology and integrating it appropriately with desired clinical practices. It provides a description of the wide range of responsibilities clinical engineers encounter, describes technology management and assessmen

Handbook of Deep Learning in Biomedical Engineering

Handbook of Deep Learning in Biomedical Engineering Book
Author : Valentina Emilia Balas,Brojo Kishore Mishra,Raghvendra Kumar
Publisher : Academic Press
Release : 2020-11-12
ISBN : 0128230479
Language : En, Es, Fr & De

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Book Description :

Deep Learning (DL) is a method of machine learning, running over Artificial Neural Networks, that uses multiple layers to extract high-level features from large amounts of raw data. Deep Learning methods apply levels of learning to transform input data into more abstract and composite information. Handbook for Deep Learning in Biomedical Engineering: Techniques and Applications gives readers a complete overview of the essential concepts of Deep Learning and its applications in the field of Biomedical Engineering. Deep learning has been rapidly developed in recent years, in terms of both methodological constructs and practical applications. Deep Learning provides computational models of multiple processing layers to learn and represent data with higher levels of abstraction. It is able to implicitly capture intricate structures of large-scale data and is ideally suited to many of the hardware architectures that are currently available. The ever-expanding amount of data that can be gathered through biomedical and clinical information sensing devices necessitates the development of machine learning and AI techniques such as Deep Learning and Convolutional Neural Networks to process and evaluate the data. Some examples of biomedical and clinical sensing devices that use Deep Learning include: Computed Tomography (CT), Magnetic Resonance Imaging (MRI), Ultrasound, Single Photon Emission Computed Tomography (SPECT), Positron Emission Tomography (PET), Magnetic Particle Imaging, EE/MEG, Optical Microscopy and Tomography, Photoacoustic Tomography, Electron Tomography, and Atomic Force Microscopy. Handbook for Deep Learning in Biomedical Engineering: Techniques and Applications provides the most complete coverage of Deep Learning applications in biomedical engineering available, including detailed real-world applications in areas such as computational neuroscience, neuroimaging, data fusion, medical image processing, neurological disorder diagnosis for diseases such as Alzheimer’s, ADHD, and ASD, tumor prediction, as well as translational multimodal imaging analysis. Presents a comprehensive handbook of the biomedical engineering applications of DL, including computational neuroscience, neuroimaging, time series data such as MRI, functional MRI, CT, EEG, MEG, and data fusion of biomedical imaging data from disparate sources, such as X-Ray/CT Helps readers understand key concepts in DL applications for biomedical engineering and health care, including manifold learning, classification, clustering, and regression in neuroimaging data analysis Provides readers with key DL development techniques such as creation of algorithms and application of DL through artificial neural networks and convolutional neural networks Includes coverage of key application areas of DL such as early diagnosis of specific diseases such as Alzheimer’s, ADHD, and ASD, and tumor prediction through MRI and translational multimodality imaging and biomedical applications such as detection, diagnostic analysis, quantitative measurements, and image guidance of ultrasonography

Medical Devices and Human Engineering

Medical Devices and Human Engineering Book
Author : Joseph D. Bronzino,Donald R. Peterson
Publisher : CRC Press
Release : 2018-10-08
ISBN : 1439825262
Language : En, Es, Fr & De

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Book Description :

Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering. Medical Devices and Human Engineering, the second volume of the handbook, presents material from respected scientists with diverse backgrounds in biomedical sensors, medical instrumentation and devices, human performance engineering, rehabilitation engineering, and clinical engineering. More than three dozen specific topics are examined, including optical sensors, implantable cardiac pacemakers, electrosurgical devices, blood glucose monitoring, human–computer interaction design, orthopedic prosthetics, clinical engineering program indicators, and virtual instruments in health care. The material is presented in a systematic manner and has been updated to reflect the latest applications and research findings.

The Biomedical Engineering Handbook

The Biomedical Engineering Handbook Book
Author : Joseph D. Bronzino,Donald R. Peterson
Publisher : CRC Press
Release : 2018-10-03
ISBN : 1439863113
Language : En, Es, Fr & De

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Book Description :

The definitive "bible" for the field of biomedical engineering, this collection of volumes is a major reference for all practicing biomedical engineers and students. Now in its fourth edition, this work presents a substantial revision, with all sections updated to offer the latest research findings. New sections address drugs and devices, personali

Clinical Engineering

Clinical Engineering Book
Author : Roberto Miniati,Ernesto Iadanza,Fabrizio Dori
Publisher : Academic Press
Release : 2015-12-23
ISBN : 0128038241
Language : En, Es, Fr & De

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Book Description :

Clinical Systems Engineering: New Challenges for Future Healthcare covers the critical issues relating to the risk management and design of new technologies in the healthcare sector. It is a comprehensive summary of the advances in clinical engineering over the past 40 years, presenting guidance on compliance and safety for hospitals and engineering teams. This contributed book contains chapters from international experts, who provide their solutions, experiences, and the successful methodologies they have applied to solve common problems in the area of healthcare technology. Topics include compliance with the European Directive on Medical Devices 93/42/EEC, European Norms EN 60601-1-6, EN 62366, and the American Standards ANSI/AAMI HE75: 2009. Content coverage includes decision support systems, clinical complex systems, and human factor engineering. Examples are fully supported with case studies, and global perspective is maintained throughout. This book is ideal for clinical engineers, biomedical engineers, hospital administrators and medical technology manufacturers. Presents clinical systems engineering in a way that will help users answer many questions relating to clinical systems engineering and its relationship to future healthcare needs Explains how to assess new healthcare technologies and what are the most critical issues in their management Provides information on how to carry out risk analysis for new technological systems or medical software Contains tactics on how to improve the quality and usability of medical devices

Handbook of Computational Intelligence in Biomedical Engineering and Healthcare

Handbook of Computational Intelligence in Biomedical Engineering and Healthcare Book
Author : Janmenjoy Nayak,Bighnaraj Naik,Danilo Pelusi,Asit Kumar Das
Publisher : Academic Press
Release : 2021-04-08
ISBN : 0128222611
Language : En, Es, Fr & De

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Book Description :

Handbook of Computational Intelligence in Biomedical Engineering and Healthcare helps readers analyze and conduct advanced research in specialty healthcare applications surrounding oncology, genomics and genetic data, ontologies construction, bio-memetic systems, biomedical electronics, protein structure prediction, and biomedical data analysis. The book provides the reader with a comprehensive guide to advanced computational intelligence, spanning deep learning, fuzzy logic, connectionist systems, evolutionary computation, cellular automata, self-organizing systems, soft computing, and hybrid intelligent systems in biomedical and healthcare applications. Sections focus on important biomedical engineering applications, including biosensors, enzyme immobilization techniques, immuno-assays, and nanomaterials for biosensors and other biomedical techniques. Other sections cover gene-based solutions and applications through computational intelligence techniques and the impact of nonlinear/unstructured data on experimental analysis. Presents a comprehensive handbook that covers an Introduction to Computational Intelligence in Biomedical Engineering and Healthcare, Computational Intelligence Techniques, and Advanced and Emerging Techniques in Computational Intelligence Helps readers analyze and do advanced research in specialty healthcare applications Includes links to websites, videos, articles and other online content to expand and support primary learning objectives

Instrumentation Handbook for Biomedical Engineers

Instrumentation Handbook for Biomedical Engineers Book
Author : Mesut Sahin
Publisher : CRC Press
Release : 2020-10-27
ISBN : 1466504846
Language : En, Es, Fr & De

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Book Description :

The book fills a void as a textbook with hands-on laboratory exercises designed for biomedical engineering undergraduates in their senior year or the first year of graduate studies specializing in electrical aspects of bioinstrumentation. Each laboratory exercise concentrates on measuring a biophysical or biomedical entity, such as force, blood pressure, temperature, heart rate, respiratory rate, etc., and guides students though all the way from sensor level to data acquisition and analysis on the computer. The book distinguishes itself from others by providing electrical circuits and other measurement setups that have been tested by the authors while teaching undergraduate classes at their home institute over many years. Key Features: • Hands-on laboratory exercises on measurements of biophysical and biomedical variables • Each laboratory exercise is complete by itself and they can be covered in any sequence desired by the instructor during the semester • Electronic equipment and supplies required are typical for biomedical engineering departments • Data collected by undergraduate students and data analysis results are provided as samples • Additional information and references are included for preparing a report or further reading at the end of each chapter Students using this book are expected to have basic knowledge of electrical circuits and troubleshooting. Practical information on circuit components, basic laboratory equipment, and circuit troubleshooting is also provided in the first chapter of the book.

The Clinical Nanomedicine Handbook

The Clinical Nanomedicine Handbook Book
Author : Sara Brenner
Publisher : CRC Press
Release : 2013-12-13
ISBN : 1439834784
Language : En, Es, Fr & De

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Book Description :

Designed to foster a stronger awareness and exploration of the subject by practicing clinicians, medical researchers and scientists, The Clinical Nanomedicine Handbook discusses the integration of nanotechnology, biology, and medicine from a clinical point of view. The book highlights relevant research and applications by specialty; it examines nanotechnology in depth, and the potential to solve medical problems. It also increases literacy in nanotechnology, and allows for more effective communication and collaboration between disciplines. Details worldwide developments in nanomedicine Provides a comprehensive roadmap of the state of nanomedicine in numerous medical specialties Bridges the gap between basic science research, engineering, nanotechnology, and medicine This text discusses what nanomedicine is, how it is currently used, and considers its potential for future applications. It serves as a reference for clinicians, including physicians, nurses, health-care providers, dentists, scientists, and researchers involved in clinical applications of nanotechnology.

Medical Equipment Maintenance

Medical Equipment Maintenance Book
Author : Binseng Wang
Publisher : Morgan & Claypool Publishers
Release : 2012-10-01
ISBN : 1627050574
Language : En, Es, Fr & De

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Book Description :

In addition to being essential for safe and effective patient care, medical equipment also has significant impact on the income and, thus, vitality of healthcare organizations. For this reason, its maintenance and management requires careful supervision by healthcare administrators, many of whom may not have the technical background to understand all of the relevant factors. This book presents the basic elements of medical equipment maintenance and management required of healthcare leaders responsible for managing or overseeing this function. It will enable these individuals to understand their professional responsibilities, as well as what they should expect from their supervised staff and how to measure and benchmark staff performance against equivalent performance levels at similar organizations. The book opens with a foundational summary of the laws, regulations, codes, and standards that are applicable to the maintenance and management of medical equipment in healthcare organizations. Next, the core functions of the team responsible for maintenance and management are described in sufficient detail for managers and overseers. Then the methods and measures for determining the effectiveness and efficiency of equipment maintenance and management are presented to allow performance management and benchmarking comparisons. The challenges and opportunities of managing healthcare organizations of different sizes, acuity levels, and geographical locations are discussed. Extensive bibliographic sources and material for further study are provided to assist students and healthcare leaders interested in acquiring more detailed knowledge. Table of Contents: Introduction / Regulatory Framework / Core Functions of Medical Equipment Maintenance and Management / CE Department Management / Performance Management / Discussion and Conclusions

Biological and Biomedical Coatings Handbook

Biological and Biomedical Coatings Handbook Book
Author : Sam Zhang
Publisher : CRC Press
Release : 2011-05-24
ISBN : 1439849986
Language : En, Es, Fr & De

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Book Description :

Written in a versatile, contemporary style that will benefit both novice and expert alike, Biological and Biomedical Coatings Handbook, Two-Volume Set covers the state of the art in the development and implementation of advanced thin films and coatings in the biological field. Consisting of two volumes—Processing and Characterization and Applications—this handbook details the latest understanding of advances in the design and performance of biological and biomedical coatings, covering a vast array of material types, including bio-ceramics, polymers, glass, chitosan, and nanomaterials. Contributors delve into a wide range of novel techniques used in the manufacture and testing of clinical applications for coatings in the medical field, particularly in the emerging area of regenerative medicine. An exploration of the fundamentals elements of biological and biomedical coatings, the first volume, Processing and Characterization, addresses: Synthesis, fabrication, and characterization of nanocoatings The sol-gel method and electrophoretic deposition Thermal and plasma spraying Hydroxyapatite and organically modified coatings Bioceramics and bioactive glass-based coatings Hydrothermal crystallization and self-healing effects Physical and chemical vapor deposition Layered assembled polyelectrolyte films With chapters authored by world experts at the forefront of research in their respective areas, this timely set provides searing insights and practical information to explore a subject that is fundamental to the success of biotechnological pursuits.

Biomedical Engineering Fundamentals

Biomedical Engineering Fundamentals Book
Author : Joseph D. Bronzino,Donald R. Peterson
Publisher : CRC Press
Release : 2014-12-17
ISBN : 1439825181
Language : En, Es, Fr & De

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Book Description :

Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering. Biomedical Engineering Fundamentals, the first volume of the handbook, presents material from respected scientists with diverse backgrounds in physiological systems, biomechanics, biomaterials, bioelectric phenomena, and neuroengineering. More than three dozen specific topics are examined, including cardiac biomechanics, the mechanics of blood vessels, cochlear mechanics, biodegradable biomaterials, soft tissue replacements, cellular biomechanics, neural engineering, electrical stimulation for paraplegia, and visual prostheses. The material is presented in a systematic manner and has been updated to reflect the latest applications and research findings.

Fermentation and Biochemical Engineering Handbook 2nd Ed

Fermentation and Biochemical Engineering Handbook  2nd Ed  Book
Author : Henry C. Vogel,Celeste M. Todaro
Publisher : William Andrew
Release : 1996-12-31
ISBN : 0815517130
Language : En, Es, Fr & De

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Book Description :

This is a well-rounded handbook of fermentation and biochemical engineering presenting techniques for the commercial production of chemicals and pharmaceuticals via fermentation. Emphasis is given to unit operations fermentation, separation, purification, and recovery. Principles, process design, and equipment are detailed. Environment aspects are covered. The practical aspects of development, design, and operation are stressed. Theory is included to provide the necessary insight for a particular operation. Problems addressed are the collection of pilot data, choice of scale-up parameters, selection of the right piece of equipment, pinpointing of likely trouble spots, and methods of troubleshooting. The text, written from a practical and operating viewpoint, will assist development, design, engineering and production personnel in the fermentation industry. Contributors were selected based on their industrial background and orientation. The book is illustrated with numerous figures, photographs and schematic diagrams.

Handbook of Neuroemergency Clinical Trials

Handbook of Neuroemergency Clinical Trials Book
Author : Brett E. Skolnick,Wayne M. Alves
Publisher : Academic Press
Release : 2017-11-13
ISBN : 0128041013
Language : En, Es, Fr & De

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Book Description :

Handbook of Neuroemergency Clinical Trials, Second Edition, focuses on the practice of clinical trials in acute neuroscience populations, or what have been called neuroemergencies. Neuroemergencies are complex, life-threatening diseases and disorders, often with devastating consequences, including death or disability. The overall costs are staggering in terms of annual incidence and costs associated with treatment and survival, yet despite their significance as public health issues, there are few drugs and devices available for definitive treatment. The book focuses on novel therapies and the unique challenges their intended targets pose for the design and analysis of clinical trials. This volume provides neurologists, neuroscientists, and drug developers with a more complete understanding of the scientific and medical issues of relevance in designing and initiating clinical development plans for novel drugs intended for acute neuroscience populations. The editors provide the best understanding of the pitfalls associated with acute CNS drug development and the best information on how to approach and solve issues that have plagued drug development. Presents a comprehensive overview on clinical trials and drug development challenges in acute neuroscience populations Provides neurologists, neuroscientists and drug developers with a complete understanding of scientific and medical issues related to designing clinical trials Edited by leaders in the field who have designed and managed over 50 neuroemergency clinical trials