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Chronic Traumatic Encephalopathy CTE

Chronic Traumatic Encephalopathy  CTE  Book
Author : Charles J. Golden,Matthew R. Zusman
Publisher : Springer
Release : 2019-06-20
ISBN : 3030232883
Language : En, Es, Fr & De

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Book Description :

The term chronic traumatic encephalopathy (CTE) has recently gained a significant amount of media coverage. However, a large proportion of the information disseminated through the media pertaining to the etiology, neuropathology, and clinical manifestations of CTE are not corroborated by empirical research, and are disputed by prominent researchers who study sports related head injury. This book reviews the existing literature pertaining to these components of CTE and includes unique case studies of several retired NFL players that received a comprehensive neuropsychological battery from a board certified neuropsychologist, among other populations. It investigates the claim that CTE causes depression, violent behavior, and an increased risk for suicide by providing an in depth discussion using empirical data. Highlighting the importance of adhering to post concussion protocol and appreciating the long-term consequences of repeated head trauma, this unique review of the current research on CTE will be useful to students and professionals in psychology and neurology.

Chronic Traumatic Encephalopathy

Chronic Traumatic Encephalopathy Book
Author : Andrew E. Budson,Ann C Mckee,Robert C. Cantu,Robert A. Stern
Publisher : Elsevier Health Sciences
Release : 2017-07-14
ISBN : 0323544266
Language : En, Es, Fr & De

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Book Description :

Get a thorough, expert overview of the many key facets of chronic traumatic encephalopathy (CTE) with this concise, practical resource by Drs. Andrew E. Budson, Ann C. McKee, Robert C. Cantu, and Robert A. Stern. This easy-to-read reference is based on lectures from Boston University’s Alzheimer’s Disease Center’s November 2016 two-day conference on CTE.

Impact of Chronic Traumatic Encephalopathy on American Football

Impact of Chronic Traumatic Encephalopathy on American Football Book
Author : Anonim
Publisher : GRIN Verlag
Release : 2020-10-07
ISBN : 3346264742
Language : En, Es, Fr & De

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Book Description :

Pre-University Paper from the year 2018 in the subject Health - Sport - Sport Medicine, Therapy, Prevention, Nutrition, grade: 1,0, , language: English, abstract: This paper gives an overview about the current discussion oft he impact of Chronic Traumatic Encephalopathy (CTE) on American Football. Therefore, chapter 2 gives a brief historic overview on the research of head injuries, defines the disease, analyses symptoms, risk factors and stages of CTE as well as the current medical therapies. Football is not only a multi-million-dollar business but represents the American dream and way of life like no other sport. An overview of the different involved stakeholders and their economic and individual interests will be given. This economic and cultural importance of football for the nation will be highlighted and explored in chapter 3. Chapter 4 explores the impact of CTE on the sport. This covers the current research and development of new materials and future technologies in personal protection equipment and also changes in the rules and format of the game. Consequences of awareness campaigns and controversial debates will be highlighted. Chapter 5 evaluates the different aspects, discusses the impact CTE will have on American football and gives an outlook for the future of the game.

CTE Media and the NFL

CTE  Media  and the NFL Book
Author : Travis R. Bell,Janelle Applequist,Christian Dotson-Pierson
Publisher : Rowman & Littlefield
Release : 2019-06-25
ISBN : 1498570577
Language : En, Es, Fr & De

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Book Description :

This book examines the mediated construction of chronic traumatic encephalopathy (CTE) and its rise to public and political prominence by way of its direct connection with the NFL. More broadly, this book explores how this relationship situates in and through the sports/media complex.

Mild Chronic Traumatic Encephalopathy Neuropathology in People with No Known Participation in Contact Sports Or History of Repetitive Neurotrauma

Mild Chronic Traumatic Encephalopathy Neuropathology in People with No Known Participation in Contact Sports Or History of Repetitive Neurotrauma Book
Author : Pekka J. Karhunen
Publisher : Unknown
Release : 2017
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Background: It has been asserted that Chronic traumatic encephalopathy (CTE) pathology is only present in former athletes and others who have been exposed to repetitive concussions, subconcussive blows, or both. However, researchers have recently reported that similar pathology is also present in people who have now known exposure to repetitive neurotrauma. We hypothesized that CTE pathology would be present in men who had no known history of repetitive neurotrauma. Methods: Comprehensive medical record reviews and health surveys completed by a family member were completed for the eight men in this case series. Post-mortem tissue from multiple brain regions was immunostained for hyperphosphorylated tau (p-tau) to assess for CTE pathology, Braak stage, and aging-related p-tau. Tissue was immunostained for amyloid-u03b2 to approximate Thal amyloid phase and CERAD plaque score. The National Institute on Aging-Alzheimer's Association 2012 consensus recommendations for Alzheimeru2019s disease neuropathologic changes were used. TDP-43 immunohistochemistry was performed on medial temporal lobe including hippocampus. Amyloid-beta precursor protein and neurofilament protein immunostains were performed to evaluate for possible axonal trauma. Alpha-synuclein immunostains were performed to rule out synucleinopathy. Basal ganglia were stained with the Prussian blue reaction for iron. Results: Six of the eight cases (i.e., 75%) showed p-tau in neurons, astrocytes, and cell processes around small blood vessels in an irregular pattern at the depths of the cortical sulci. The changes were focal and limited in terms of overall extent. Two of the eight cases had a history of traumatic brain injury and one of them showed CTE pathology. Five of the six cases (83%) with no known history of neurotrauma met consensus criteria for CTE. Conclusion: This study adds to the emerging literature indicating that CTE pathology (or CTE-like pathology) is present in people not known to have experienced multiple concussions or subconcussive blows to the head.

Handbook of Traumatic Brain Injury and Neurodegeneration

Handbook of Traumatic Brain Injury and Neurodegeneration Book
Author : R.J. Castellani
Publisher : IOS Press
Release : 2020-04-24
ISBN : 164368065X
Language : En, Es, Fr & De

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Book Description :

Holbourne’s theory that rotational head movement and shear strains were limiting factors in producing acute parenchymal brain damage was a watershed moment in understanding traumatic brain injury (TBI). Long term effects, and in particular neurodegenerative proteinopathy subsequent to TBI, remain theoretical, notwithstanding the poorly understood ‘punch drunk’ syndrome of the early and mid-20th century, and the 21st century concept of chronic traumatic encephalopathy. This book, the Handbook of Traumatic Brain Injury and Neurodegeneration, has as its theme the marriage between neurodegenerative disease and neurotrauma through TBI surrogates such as sport, military service, and experimental models, and the legitimacy of that marriage. In the 32 contributions included here, this handbook not only explores the deleterious effects of genuine TBI, but also, and more importantly, the relationship between TBI and neurodegeneration. Controversy notwithstanding, there is much to be learned about the biological effects of TBI, substrates for long-term sequelae, the relationship between TBI and diverse neuropsychiatric disorders, and targets for therapy. The overall message to the neuroscience community from these papers may be a cautionary tale. The null hypothesis, that there is no causal relationship between TBI and progressive neurodegenerative disease, appears to be very much in play, and the book will be of interest to all those working in the field.

Neuropsychological Features of Chronic Traumatic Encephalopathy

Neuropsychological Features of Chronic Traumatic Encephalopathy Book
Author : Arlene Raffo
Publisher : Unknown
Release : 2014
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Chronic Traumatic Encephalopathy (CTE) is proposed to be a neurodegenerative disease thought to develop as a result of recurrent brain injuries. At present, CTE can only be formally diagnosed at postmortem autopsy; however, advances in biomedical research are being made to better understand the pathological changes that occur in the brain and lead to the multiple physical, cognitive, and emotional problems which characterize this progressive disease. From a neuropsychological perspective, the field has very limited knowledge regarding the cognitive and psychological markers that are the most sensitive and specific in identifying and differentially diagnosing this disease. This doctoral work proposes a neuropsychological research battery that is designed to improve the diagnosis of CTE in living persons. The battery also presents measures that may assist with differential diagnosis. To do so, an extensive review of the literature was conducted to determine the neuropsychological instruments that are sensitive to the effects of recurrent brain trauma and specific to CTE versus other degenerative diseases, in order to assist with diagnosis. Limitations and future directions are also discussed.

Traumatic Brain Injury

Traumatic Brain Injury Book
Author : Arthur Gillard
Publisher : Greenhaven Publishing LLC
Release : 2012-10-19
ISBN : 073777312X
Language : En, Es, Fr & De

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Book Description :

There are more than 200,000 cases of traumatic brain injury in the United States every year. It is a major cause of deaths and disabilities. This guidebook provides essential information on Traumatic Brain Injury, but also presents first-person narratives by people coping with Traumatic Brain Injury. Readers will learn from the words of patients, family members, or caregivers. The symptoms, causes, treatments, and potential cures are explained in detail. Alternative treatments are also covered. Each essay is carefully edited and presented with an introduction, so that they are accessible for student researchers and readers.

Impact of Chronic Traumatic Encephalopathy Information on Perceptions of Illness

Impact of Chronic Traumatic Encephalopathy Information on Perceptions of Illness Book
Author : Carolyn M. Cook
Publisher : Unknown
Release : 2019
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Mild traumatic brain injury (mTBI) is a significant public health concern and has been a frequent topic in the media in recent years. Over the past decade, chronic traumatic encephalopathy (CTE), which has been suggested to be the result of repeated concussions and to involve symptoms such as deterioration in attention, concentration, and memory, among others, has also become the subject of much media attention. However, media articles about CTE often involve personal stories and anecdotes rather than any discussion of the limited CTE research. This is problematic because individuals who have sustained one or multiple mTBIs often use information from the media, along with information from other sources, such as healthcare providers and family members, to form beliefs about the identity, severity, consequences, and timeline of their injury and recovery. Media articles that sensationalize CTE or rely solely on personal anecdotes may lead individuals to form beliefs about their injury and expected recovery that are incorrect. Individuals who form such erroneous beliefs may be at increased risk of experiencing persistent symptoms after mTBI. The present study examined the impact of reading different types of CTE information on symptom endorsement, illness beliefs, and self-reported impairment in individuals with a history of mTBI.

Traumatic Brain Injury

Traumatic Brain Injury Book
Author : Jack W. Tsao
Publisher : Springer Nature
Release : 2019-12-03
ISBN : 3030224368
Language : En, Es, Fr & De

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Book Description :

This thoroughly revised and updated work covers numerous advances in traumatic brain injury diagnosis, evaluation, treatment, and pathophysiology. Since publication of the first edition in 2012, there has been greatly increased public awareness of the clinical consequences of even the mildest of head injuries, and the result has been a concerted effort of countries around the world to increase research funding. This second edition continues to focus on mild traumatic brain injury--or concussion--and contains updates to all the original chapters as well as adding new chapters addressing clinical sequelae, including pediatric concussion, visual changes, chronic traumatic encephalopathy, and blast-associated TBI. Traumatic Brain Injury: A Clinician's Guide to Diagnosis, Management, and Rehabilitation, Second Edition, is a comprehensive resource designed for neurologists, primary care clinicians, sports physicians, and other medical providers, including psychologists and neuropsychologists, as well as athletic trainers who may evaluate and care for individuals who have sustained a TBI. The book features summaries of the most pertinent areas of diagnosis and therapy, which can be readily accessed by the busy clinician/professional. In addition, the book's treatment algorithms provide a highly practical reference to cutting edge therapies, and an updated appendix of ICD codes is included. An outstanding contribution to the literature, Traumatic Brain Injury: A Clinician's Guide to Diagnosis, Management, and Rehabilitation, Second Edition, again offers an invaluable resource for all providers who treat patients with TBI.

Kids Sports and Concussion A Guide for Coaches and Parents 2nd Edition

Kids  Sports  and Concussion  A Guide for Coaches and Parents  2nd Edition Book
Author : William Paul Meehan III
Publisher : ABC-CLIO
Release : 2018-02-08
ISBN : 1440858039
Language : En, Es, Fr & De

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Book Description :

A comprehensive summary of sport-related concussion for parents, coaches, and athletes that considers the physics and biology behind the injury, identifies what can be done to reduce the risk of its occurrence, and describes how to properly respond to a suspected concussion. • Provides a detailed but easy-to-understand, jargon-free explanation of types of trauma and the forces that result in a concussion as well as what happens to brain cells when the brain suffers a concussion • Presents the facts about sport-related concussion and the potential for cumulative effects of sport-related concussions, including a discussion about chronic traumatic encephalopathy • Informs athletes, parents, and coaches about ways in which to prepare for a possible concussion, how to respond to a potential concussion, and steps to take to decrease the risk of a concussion injury

Traumatic Brain Injury An Issue of Neurosurgery Clinics of North America

Traumatic Brain Injury  An Issue of Neurosurgery Clinics of North America  Book
Author : Paul M. Vespa,Daniel Hirt,Geoffrey T. Manley
Publisher : Elsevier Health Sciences
Release : 2016-09-19
ISBN : 0323463207
Language : En, Es, Fr & De

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Book Description :

The consequences of a brain injury can affect all aspects of our lives, including our personality. Brain injuries do not heal like other injuries and symptoms may appear right away or may not be present for days or weeks after the injury. This issue will include Past, Present, and Future of TBI research; Pathophysiology of TBI; Advances in brain imaging of TBI; and many more articles leading up to Degenerative Disease following Traumatic Brain Injury.

The Relationship Between Repetitive Traumatic Brain Injury and Chronic Traumatic Encephalopathy and Its Effects on Retired Professional Football Players

The Relationship Between Repetitive Traumatic Brain Injury and Chronic Traumatic Encephalopathy and Its Effects on Retired Professional Football Players Book
Author : Jessica Rossi
Publisher : Unknown
Release : 2016
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Relationship Between Repetitive Traumatic Brain Injury and Chronic Traumatic Encephalopathy and Its Effects on Retired Professional Football Players book written by Jessica Rossi, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Brain Injury as a Neurodegenerative Disorder

Brain Injury as a Neurodegenerative Disorder Book
Author : Robin E.A. Green
Publisher : Frontiers Media SA
Release : 2017-04-20
ISBN : 2889199010
Language : En, Es, Fr & De

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Book Description :

It has been long assumed that following the resolution of acute injuries, traumatic brain injury represents a stable neural entity. However, there is growing evidence that a single moderate-severe brain injury may instead trigger an ongoing deteriorative process that commences sub-acutely, and occurs regardless of age. For scientists and clinicians, it is critical to examine this body of evidence and to explore its implications. Do the findings represent a neurodegenerative process or can they be alternatively explained? What are the neural, behavioural and functional characteristics of this progressive deterioration? Such information is needed to develop treatments to prevent or mitigate decline, and to inform the clinical care of brain injured patients. Research and clinical practice are influenced by the assumption that moderate-severe TBI is non-progressive, with few studies exploring treatments to prevent progression, and rehabilitation typically concentrated in the early stages of injury. Brain injuries can never be fully prevented. However, understanding that such progressive deterioration occurs opens a novel area of research - prevention of secondary decline - offering new possibilities for the improvement of long-term outcomes in people with traumatic brain injury.

Chronic Traumatic Encephalopathy CTE

Chronic Traumatic Encephalopathy  CTE  Book
Author : Charles J. Golden,Matthew R. Zusman
Publisher : Springer
Release : 2019-08-27
ISBN : 9783030232870
Language : En, Es, Fr & De

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Book Description :

The term chronic traumatic encephalopathy (CTE) has recently gained a significant amount of media coverage. However, a large proportion of the information disseminated through the media pertaining to the etiology, neuropathology, and clinical manifestations of CTE are not corroborated by empirical research, and are disputed by prominent researchers who study sports related head injury. This book reviews the existing literature pertaining to these components of CTE and includes unique case studies of several retired NFL players that received a comprehensive neuropsychological battery from a board certified neuropsychologist, among other populations. It investigates the claim that CTE causes depression, violent behavior, and an increased risk for suicide by providing an in depth discussion using empirical data. Highlighting the importance of adhering to post concussion protocol and appreciating the long-term consequences of repeated head trauma, this unique review of the current research on CTE will be useful to students and professionals in psychology and neurology.

Manual of Traumatic Brain Injury

Manual of Traumatic Brain Injury Book
Author : Felise S. Zollman, MD, FAAN, FAAMA
Publisher : Springer Publishing Company
Release : 2016-05-28
ISBN : 1617052698
Language : En, Es, Fr & De

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Book Description :

The Manual provides an excellent road map to the many topics relevant in the diagnosis, treatment, and long-term management of individuals with TBI. As such, the book can serve either as a fine introduction for the uninitiated or as a valued reference for seasoned clinicians. I highly recommend [it]... Journal of Head Trauma Rehabilitation This is a stellar quality book that will be beneficial for every member of the multidisciplinary team that is required to treat patients with TBI. It offers a concise but broad and informative view of the disorder, and can serve as an easy-to-read and access primary text. 4 Stars! Doody’s Reviews Now completely revised and updated, Manual of Traumatic Brain Injury:Assessment and Management, Second Edition is a comprehensive evidence-based guide to brain injury diagnosis, treatment, and recovery, delivered in a succinct format designed for targeted access to essential content. This concise text, featuring internationally known contributors drawn from leading TBI programs, is organized into five sections. Part 1 discusses fundamental concepts needed to provide a context for clinical decision-making. Part 2 covers mild TBI, from natural history to sports-related concussion, post-concussion syndrome, and more. Part 3 focuses on moderate to severe TBI and contains chapters on pre-hospital, emergency and ICU care, rehabilitation, community reintegration, management of associated impairments, and post-injury outcomes. Part 4 covers the complications and long-term sequelae that may arise in patients with TBI, including spasticity, movement disorders, posttraumatic seizures, hydrocephalus, behavioral and sleep disturbances, and chronic traumatic encephalopathy (CTE). Part 5 focuses on special considerations and resources, including issues specific to selected populations or injury environments (military, pediatric, workers compensation and older patients), as well as return to work and medico-legal issues in TBI. Comprehensively updated to reflect the current state of the art in this rapidly evolving field, this book is a must-have for neurologists, physiatrists, primary care physicians, mental health professionals, social workers, and other healthcare providers who treat TBI patients. New to the Second Edition: "Key Points" section in each chapter crystallizes important clinical pearls New chapters cover anoxia complicating TBI, screening for emotional distress in TBI patients, management of chronic behavioral disturbances, and assistive technology Every chapter has been updated to reflect current evidence-based practice

A Historical Foundation of Cte in Football Players

A Historical Foundation of Cte in Football Players Book
Author : Bennet Omalu
Publisher : Unknown
Release : 2014-03
ISBN : 9780991635313
Language : En, Es, Fr & De

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Book Description :

Dr. Omalu identified and described Chronic Traumatic Encephalopathy [CTE] in American football players beginning in 2002 when he performed an autopsy on Mike Webster.Between 2002 and 2007, Dr. Omalu identified the very first five cases of CTE in football players, and identified the very first case of CTE in a professional American wrestler in 2007 when he examined the brain of Chris Benoit. In 2007 and 2009, Dr. Omalu again, identified the very first two cases of CTE in retired war veterans suffering from PTSD.

Critical Perspectives on Minors Playing High Contact Sports

Critical Perspectives on Minors Playing High Contact Sports Book
Author : John A. Torres
Publisher : Enslow Publishing, LLC
Release : 2016-12-15
ISBN : 0766081370
Language : En, Es, Fr & De

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Book Description :

Playing team sports has many benefits, and yet high-contact sports such as football and rugby have also been linked to serious injuries, including concussions, and a higher risk of dementia, depression, and Parkinson’s disease. How can we weigh the potential benefits of contact sports with their potentially serious risks? This text provides primary source evidence from doctors, scientists, and experts in the field of sports medicine, as well as ordinary people’s viewpoints, in order to help students reach their own conclusions about the risks related to high-contact sports.

Chronic Traumatic Encephalopathy

Chronic Traumatic Encephalopathy Book
Author : Anthony Salvitti,Tony Salvitti
Publisher : CreateSpace
Release : 2013-11
ISBN : 9781493718986
Language : En, Es, Fr & De

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Book Description :

CTE (Chronic traumatic encephalopathy) What you need to know about sports, is the very, much overdue enlightenment about the danger of contact sports and the long term consequences. This book is a warning for all parents and athletes a like. If you engaged in this type of athletic event you will have this result, if not now then years down the road and no cure but one-Do not engaged in the practice of contact sports.

Radiological pathological Correlations in Chronic Traumatic Encephalopathy

Radiological pathological Correlations in Chronic Traumatic Encephalopathy Book
Author : Mihika Gangolli
Publisher : Unknown
Release : 2018
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease that has been increasingly linked to traumatic brain injury. The neuropathology that distinguishes CTE from other tauopathies includes hyperphosphorylated tau (pTau) tangles and tau positive astrocytes irregularly distributed in cortical sulcal depths and clustered around perivascular foci. These features are clearly identified using immunohistochemistry, but are undetectable to current clinical imaging methods. Diffusion imaging has been proposed as a noninvasive method to detect the pathognomonic lesion of CTE in vivo because of its high sensitivity to microstructural alterations in tissue structure. While several diffusion imaging approaches, ranging from diffusion tensor imaging (DTI) to more advanced schemes such as generalized q-sampling imaging (GQI) and diffusion kurtosis imaging (DKI) may prove useful, the relationship between changes in diffusion-derived metrics and the underlying pathology remains unknown. We have developed and implemented a method of perform radiological-pathological correlations in tissues with diagnoses of CTE, aimed to determine whether high spatial resolution diffusion imaging is capable of sensitively detecting pTau pathology.Human ex vivo cortical tissues diagnoses with Stage III/IV CTE, Alzheimer's disease (AD) or frontotemporal lobar dementia (FTLD) were scanned in an 11.74T Agilent MRI scanner using DTI, GQI and DKI acquisition schemes with isotropic in-plane spatial resolution of 250[mu]m and 500[mu]m slice thickness. Following image acquisition, tissues were sectioned and stained for histopathological markers including AT8 (pTau), GFAP (astrocytes) and Myelin Black Gold II (myelinated white matter). A custom script was used to co-register histological to MRI images, allowing for the ability to perform high spatial resolution correlations of histological with diffusion metrics. Using this approach, we found no relationship between pTau in sulcal depths and any of our DTI, GQI and DKI based measures. Interestingly, we found that white matter underlying sulcal depths in CTE tissues showed signs of disruption, a finding that we did not observe in AD or FTLD tissues. Furthermore, white matter integrity in these regions was correlated with fractional anisotropy. These findings demonstrate that high spatial resolution diffusion imaging is capable of detecting white matter disorganization closely related to pTau pathology in CTE, and may provide a more sensitive and specific means of diagnosing CTE.