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Chronic Pain And Brain Abnormalities

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Chronic Pain and Brain Abnormalities

Chronic Pain and Brain Abnormalities Book
Author : Carl Y. Saab
Publisher : Academic Press
Release : 2013-06-28
ISBN : 0124058965
Language : En, Es, Fr & De

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Book Description :

It is only natural for someone in pain to attend to the body part that hurts. Yet this book tells the story of persistent pain having negative effects on brain function. The contributors, all leading experts in their respective fields of pain electrophysiology, brain imaging, and animal models of pain, strive to synthesize compelling and, in some ways, connected hypotheses with regard to pain-related changes in the brain. Together, they contribute their clinical, academic, and theoretical expertise in a comprehensive overview that attempts to define the broader philosophical context of pain (disentangling sensical from nonsensical claims), list the changes known to take place in the brains of individuals with chronic pain and animal models of pain, address the possible causes and mechanisms underlying these changes, and detail the techniques and analytical methods at our disposal to "visualize" and study these changes. Philosophical and social concepts of pain; testimonials of chronic-pain patients Clinical data from pain patients’ brains Advances in noninvasive brain imaging for pain patients Combining theoretical and empirical approaches to the analysis of pain-related brain function Manipulation of brain function in animal models Emerging neurotechnology principles for pain diagnostics and therapeutics

The Neurological Basis of Pain

The Neurological Basis of Pain Book
Author : Marco Pappagallo
Publisher : McGraw Hill Professional
Release : 2005
ISBN : 9780071440875
Language : En, Es, Fr & De

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Book Description :

Pappagallo (neurology, Albert Einstein College of Medicine; chronic pain, Beth Israel Medical Center) compiles the latest work from international contributors on the scientific basis of pain medicine, issues related to the pain physician, pain syndromes and disorders, and therapies. Some topics examined include opioid pharmacology, brain imaging of

Fibromyalgia and Other Central Pain Syndromes

Fibromyalgia and Other Central Pain Syndromes Book
Author : Daniel Jeffrey Wallace,Daniel J. Clauw, M.D.
Publisher : Lippincott Williams & Wilkins
Release : 2005
ISBN : 9780781752619
Language : En, Es, Fr & De

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Book Description :

This volume is the first comprehensive text devoted to fibromyalgia and other centrally mediated chronic pain syndromes. Leading experts examine the latest research findings on these syndromes and present evidence-based reviews of current controversies. Chapters discuss the definition, epidemiology, and pathophysiology of chronic pain and fibromyalgia, the clinical presentations of fibromyalgia syndrome, and central sensitization syndromes associated with chronic neuromuscular pain. The contributors thoroughly examine various approaches to evaluation and management of patients with fibromyalgia and chronic pain. Other chapters focus on disability issues, prognosis, and future research directions. A critically reviewed listing of Websites and other resources is included.

Chronic Pain

Chronic Pain Book
Author : Gary W. Jay
Publisher : CRC Press
Release : 2007-06-20
ISBN : 0849330467
Language : En, Es, Fr & De

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Book Description :

Providing a general approach to the understanding and management of all forms of chronic pain, this book offers a clear and reader-friendly format that clarifies procedures in the diagnosis, assessment, and treatment of the most common chronic non-cancer pain entities. Describing various types of intractable non-cancer pain, including neuropathic, somatic, and visceral pain, this source discusses the many available types of treatments, including opioid and adjunctive pain medications, and the safe and proper use of narcotics for treating chronic pain.

100 Questions and Answers About Chronic Pain

100 Questions and Answers About Chronic Pain Book
Author : Jain
Publisher : Jones & Bartlett Learning
Release : 2010-12-15
ISBN : 1449632823
Language : En, Es, Fr & De

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Book Description :

Empower Yourself! Millions of Americans suffer from chronic pain ranging from mild to excruciating. If you or a loved one experience chronic pain, 100 Questions and Answers About Chronic Pain offers essential and practical guidance. This easy-to-read guide provides authoritative answers to common questions asked by patients and their families about chronic pain. Topics include introduction to pain disorders, neurobiology of pain, treatments, and coping strategies for thriving despite pain. 100 Questions and Answers About Chronic Pain is an essential resource for anyone coping with the physical and emotional turmoil of this disorder.

Clinical Neurotherapy

Clinical Neurotherapy Book
Author : Erbil Dursun,Nigar Dursun
Publisher : Elsevier Inc. Chapters
Release : 2013-10-18
ISBN : 0128061499
Language : En, Es, Fr & De

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Book Description :

Download Clinical Neurotherapy book written by Erbil Dursun,Nigar Dursun, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Autoimmune Brain

The Autoimmune Brain Book
Author : David S. Younger
Publisher : Rowman & Littlefield Publishers
Release : 2019-11-10
ISBN : 1538117711
Language : En, Es, Fr & De

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Book Description :

There are millions of people who experience issues related to brain health--depression, attention issues, anxiety, forgetfulness, fatigue, and even chronic pain--yet can’t figure out what’s causing their problems and can’t find any relief. They may have seen a myriad of doctors, many of whom do not take their complaints seriously, or worse, turn to the easy, often inappropriate fix of antidepressants or antianxiety medications. Traditional medications, supplements, or other therapies haven’t worked. No matter what their age--from children to teens or seniors--people and their loved ones are frustrated, scared, and confused by their continued poor health. Countless others display severe psychiatric symptoms that seem to come out of nowhere, ranging from tics, obsessive-compulsive behaviors and anxiety, to depression, bipolar-like mood swings, and even borderline personality disorder and suicidal ideas. . Sometimes, the people affected are the only ones that notices a change to the way they think or feel, and they suffer in silence. Or, they reach out to try to get help, and are all too frequently misdiagnosed. Now, Dr. David Younger, a world-renowned physician, provides relief to these patients and their families. His diagnostic techniques and treatment protocols will help readers identify the true cause of their symptoms and put them on a clear path to healing so they no longer feel unbalanced, out of control, forgetful, and exhausted. THE AUTOIMMUNE BRAIN connects common brain health symptoms to the changes in the immune system, and particularly bacterial, viral, and parasitic infections. In this book, Dr. Younger explains his groundbreaking research and adds a new component: how traumatic stress (whether physical or emotional) and genetics affects this same triad as inextricable factors in initiating disease and brain health symptoms. In fact, a change in personality, behavior, coping style, and one’s emotional state may be the first clue that there is a health problem brewing somewhere else in the body. Readers will find new answers to troubling conditions, including: Alzheimer’s disease Anxiety Arthritis Autism Autonomic disturbances Bacterial and viral infections Bipolar Disorder Cancer Celiac disease and gluten intolerances Chronic Fatigue Syndrome (now referred to as Systemic Exertion Intolerance Disease) Chronic Pain Dementia Depression Endocrine Disorders Immune modulatory therapy using IVIg Lyme disease and co-infections Mast cell activation syndrome Medical cannabis Obsessive Compulsive Disorder Orthostatic hypotension Peripheral Neuropathy Porphyria Post-Traumatic Stress Disorder Postural orthostatic tachycardia

HUB DISRUPTION IN PATIENTS WITH CHRONIC NECK PAIN A GRAPH ANALYTICAL APPROACH

HUB DISRUPTION IN PATIENTS WITH CHRONIC NECK PAIN  A GRAPH ANALYTICAL APPROACH Book
Author : Mira Meeus
Publisher : Unknown
Release : 2017
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Chronic pain is known to alter the brainu2019s network dynamics. These dynamics are often demonstrated by identifying alterations in the brain network topology. A common approach used for this purpose is graph theory. To date, little is known on how these potentially altered networks in chronic pain relate to the symptoms reported by these patients. Here, we applied a graph theoretical approach to identify network changes in patients suffering from chronic neck pain, a group that is often neglected in chronic pain research. Participants with chronic traumatic and non-traumatic neck pain were compared to healthy pain-free controls. They showed higher levels of self-reported symptoms of sensitization, higher levels of disability and impaired sensorimotor control. The brain suffering from chronic neck pain furthermore showed altered network properties in the posterior cingulate cortex, amygdala and pallidum compared to the healthy pain-free brain. These regions have been identified as brain hubs (i.e. regions that are responsible for orchestrating communication between other brain regions) and are therefore known to be more vulnerable in brain disorders including chronic pain. We were furthermore able to uncover associations between these altered brain network properties and the symptoms reported by patients. Our findings indicate that chronic neck pain patients reflect brain network alterations and that targeting the brain in patients might be of utmost importance.

Diagnosis and Treatment of Chronic Pain

Diagnosis and Treatment of Chronic Pain Book
Author : Nelson H. Hendler
Publisher : Unknown
Release : 1982
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Diagnosis and Treatment of Chronic Pain book written by Nelson H. Hendler, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Evaluation and Treatment of Chronic Pain

Evaluation and Treatment of Chronic Pain Book
Author : Gerald M. Aronoff
Publisher : Lippincott Williams & Wilkins
Release : 1999
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Evaluation and Treatment of Chronic Pain book written by Gerald M. Aronoff, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Neuroimaging of Pain

Neuroimaging of Pain Book
Author : Luca Saba
Publisher : Springer
Release : 2017-06-08
ISBN : 3319480464
Language : En, Es, Fr & De

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Book Description :

Authored by world renowned scientists, this book expertly reviews all the imaging techniques and exciting new methods for the analysis of the pain, including novel tracers, biomarker, metabolomic and gene-array profiling, together with cellular, genetic, and molecular approaches. Recent advances in human brain imaging techniques have allowed a better understand of the functional connectivity in pain pathways, as well as the functional and anatomical alterations that occur in chronic pain patients. Modern imaging techniques have permitted rapid progress in the understanding of networks in the brain related to pain processing and those related to different types of pain modulation. Neuroimaging of Pain is designed to be a valuable resource for radiologists, neuroradiologists, neurologists and neuroscientists, working in hospitals and universities from junior trainees to consultants.

Diagnosis and Management in Patients with Chronic Pelvic Pain Syndrome

Diagnosis and Management in Patients with Chronic Pelvic Pain Syndrome Book
Author : Jörgen Quaghebeur,Jean-Jacques Wyndaele
Publisher : Cambridge Scholars Publishing
Release : 2021-01-22
ISBN : 1527565068
Language : En, Es, Fr & De

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Book Description :

Chronic pelvic pain (CPP) involves a list of deviations with persistent pain in the pelvic area as the main factor. Multiple pain syndromes exist for this, and, after assessment, the reason for the chronic symptoms often remains unclear. The exclusion of the origins or reasons for the pain that can be treated curatively is of the greatest importance. When no reasons for the pain can be found, or when the pain cannot be healed, symptomatic treatment will be necessary. The most successful treatment of CPP is a multidisciplinary approach, bringing together doctors, nurses, physical therapists, osteopaths, and psychologists. Chronic pain has an important impact on the quality of life and strong negative consequences on the psychologic and emotional state of the patient. In addition, the success of the (usually long-term) treatment is not easy to predict. Beginning with a general discussion, this book considers pain abnormalities in the most important parts of the small pelvis. It also discusses various treatments of these issues, and delves into the psychological approach to such pain.

Dangerous Grains

Dangerous Grains Book
Author : James Braly,Ron Hoggan
Publisher : Penguin
Release : 2002-08-26
ISBN : 1440650152
Language : En, Es, Fr & De

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Book Description :

Learn the shocking truth about how gluten cereal grains effect our health Could gluten be contributing to your fatigue, stress, bloating, and ill health? Long before Grain Brain was a bestseller, Dangerous Grains was the first book to examine in depth the hazards of gluten cereal grains. James Braly, M.D., a renowned food allergy expert and Ron Hoggan, M.A., a respected patient advocate, reveal the negative impact of gluten grains. Discover the benefits of a gluten-free diet in relieving and preventing the ailments associated with celiac disease, gluten sensitivity, and more than 200 chronic illnesses, including: Cancer Autoimmune diseases Osteoporosis Brain disorders Intestinal disease Chronic pain Digestive disorders Infertility and problematic pregnancies Tracking the genetic and evolutionary history of humans and grain consumption, Dangerous Grains can help you understand how grains can affect your health, and whether you are at risk for gluten-influenced illnesses.

Clinical Pain Management Chronic Pain

Clinical Pain Management   Chronic Pain Book
Author : Peter Wilson,Paul Watson,Jennifer Haythornwaite,Troels Jensen
Publisher : CRC Press
Release : 2008-09-26
ISBN : 1444109812
Language : En, Es, Fr & De

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Book Description :

The second edition of Chronic Pain now covers a vast scientific and clinical arena, with the scientific background and therapeutic options much expanded. In common with the other titles comprising Clinical Pain Management, the volume gathers together the available evidence-based information in a reader-friendly format without unnecessary detail, an

Brain Inflammation in Chronic Pain Migraine and Fibromyalgia

Brain Inflammation in Chronic Pain  Migraine and Fibromyalgia Book
Author : Alex Vasquez
Publisher : Createspace Independent Publishing Platform
Release : 2016-03-09
ISBN : 9781530471898
Language : En, Es, Fr & De

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Book Description :

This book solves the mysteries of chronic pain disorders such as migraine and fibromyalgia by explaining that the "central sensitization" which makes the brain more sensitive to main signals is actually caused by inflammation within the brain. By understanding the 3 main components of brain inflammation -- pain, inflammation, and mitochondrial dysfunction -- patients and doctors are able to understand and then treat these painful conditions with greater success; with this knowledge patients and doctors can implement the effective and successful treatment protocol, making customizations as needed per individual patient's unique profile/pattern. This version was previously published as Pain Revolution (full color), excerpted from Chapter 5 of "Inflammation Mastery, 4th Edition" also published as a two-volume set as "Textbook of Clinical Nutrition and Functional Medicine, Vol. 2: Protocols for Common Inflammatory Disorders." The updated cover image emphasizes the importance of the brain inflammation that underlies the "central sensitization" which makes the brain more sensitive to pain. PURPOSE & AUDIENCE: This book is written to provide essential information to doctors and patients dealing with chronic pain generally, migraine and fibromyalgia specifically. The information is also relevant for cluster headache, myofascial pain syndrome, and complex regional pain syndrome. With hundreds of citations to the biomedical research literature, this book provides unique insights into the causes of and solutions for migraine and fibromyalgia as prototypic pain disorders chiefly characterized by central sensitization, glial activation, and mitochondrial dysfunction. Clinicians and patients alike will gain insights that are immediately applicable for the treatment of these conditions. Importantly, the focus of Dr Vasquez's Functional Inflammology Protocol is to skillfully address -in a structured manner- the underlying causes of pain and inflammation, not simply to alleviate pain/inflammation via drug dependency. This book details the pathophysiology and essential treatment components; additional explanations and updates are provided via video lectures and tutorials. DIGITAL: Ebook version will be published in January 2016. ABOUT THIS BOOK: This book is an excerpt from Chapter 5 of Dr Vasquez's most recent 1,200-page textbook, Inflammation Mastery, 4th Edition (2016). The information in this book has been developed over many years starting from Dr Vasquez's teaching notes in Orthopedics and Rheumatology in 2000 and 2001, then in Integrative Orthopedics (2004, 2012), Musculoskeletal Pain: Expanded Clinical Strategies (Institute for Functional Medicine, 2008), Functional Medicine Rheumatology (2014), and Human Microbiome and Dysbiosis in Clinical Disease (2015).

Motivational Perspectives on Chronic Pain

Motivational Perspectives on Chronic Pain Book
Author : Paul Karoly,Geert Crombez
Publisher : Oxford University Press
Release : 2018-08-07
ISBN : 0190627913
Language : En, Es, Fr & De

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Book Description :

Motivational Perspectives on Chronic Pain is one of the first volumes to present a cohesive account of the adaptation to chronic pain from a motivational perspective. Contributing authors from diverse areas of pain research offer comprehensive summaries of the concepts, findings, and applied methodologies that converge on the role of goals and goal-related cognitive processes, self-regulatory support mechanisms, contextual forces, and emotionality as they influence (and are influenced by) the experience of chronic pain. This volume provides readers with an up-to-date compendium of cutting-edge research and interventions that collectively illustrate the utility of viewing chronic pain neither as a "disease" nor an imposed lifestyle, but as the emergent and potentially flexible product of a complex transactional system that is bounded by both sociocultural factors and by biogenetic and neural moderating forces. Within its pages, chapters capture the vibrancy of current theory, research, and practice while pointing toward unexplored new directions. Among the important topics addressed by this distinguished group of authors include: the nature and relevance of control systems, the role of neural mechanisms on pain processing, the influence positive and negative emotion regulation play on pain management, the impact of learning and conditioning, and the often neglected influence of interpersonal processes on adjustment to chronic pain.

Trends in Clinical Deep Brain Stimulation

Trends in Clinical Deep Brain Stimulation Book
Author : Marcus L. F. Janssen,Yasin Temel
Publisher : MDPI
Release : 2021-03-17
ISBN : 3036503366
Language : En, Es, Fr & De

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Book Description :

This book covers the current trends in clinical deep brain stimulation (DBS) research. This collection of papers from experts in the field provides state of the art knowledge and future perspectives in clinical DBS research. A range of topics involved in DBS is presented, ranging from high resolution imaging, electrophysiology and personalized medicine, in a broad range of brain disorders.

Neuropsychological Function in Fibromyalgia

Neuropsychological Function in Fibromyalgia Book
Author : Katherine Hoover
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This dissertation is an investigation of declarative memory and executive function in fibromyalgia syndrome (FMS). FMS is a chronic pain syndrome with an unknown etiology. Several lines of research indicate that FMS patients may have central nervous system abnormalities. Such abnormalities may contribute to widespread pain in the absence of observable injury and cause deficits in memory and attention (attention is one aspect of executive function). FMS patients have reported problems with their memory and attention. Findings from prior investigations have demonstrated some differences but have used non-standard measures with small sample sizes. In addition, depression often occurs with FMS. Prior investigations of memory and attention have often used, or misused the presence of depression as an explanation for their findings. This study recruited, screened and tested 61 women with FMS who, for a chronic pain group, were reasonably free of depressive symptoms. A comparison group of 63 women, free of significant illnesses, and matched in age and education to their FMS counterparts were also screened and tested. Five neuropsychological tests chosen to be sensitive to the purported brain abnormalities in FMS were administered to all participants as well as measures of mood and other symptoms. FMS participants were found to have significantly poorer performance on some measures of executive function, those tapping working memory and sustained attention. Poorer performance on one aspect of declarative memory testing was also demonstrated, though the performance was not at a level that would be considered evidence of abnormal memory function. In a set of predictive analyses it was shown that neuropsychological measures were not more significant predictors of group membership than were measures of symptoms relevant to the disorder.

Functional Scalp Acupuncture

Functional Scalp Acupuncture Book
Author : Anne Angelone,Anne Angelone L Ac
Publisher : Unknown
Release : 2019-11-14
ISBN : 9781687062918
Language : En, Es, Fr & De

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Book Description :

The Functional Scalp Acupuncture (FSA) model promotes the application of neuroscience and evidenced-based acupuncture research to the treatment of chronic pain, depression, anxiety, schizophrenia, autism spectrum disorder (ASD), attention-deficit-hyperactivity-disorder (ADHD), obsessive-compulsive disorder (OCD), autoimmune, and Alzheimer's disease. Neuroscience has dramatically increased our knowledge and understanding of the underlying dysfunction in each of these conditions. As we shall soon discover, each disorder has a well-established 'neurobiological signature' that can give us clues as to where the imbalances lie and how to improve functional brain integration. In recent years, developments in neuroscience have offered significant breakthroughs in understanding the brain chemistry and neurobiology behind the symptoms associated with neuropsychiatric, neurobehavioral, neurodegenerative, and autoimmune disorders. From a neurobiological perspective, all of these disorders stem from a functionally disconnected and, therefore, asynchronous brain. Notably, in all of these disorders, the root cause can, in part, be explained by the lack of top-down control from the prefrontal cortex to subcortical limbic structures. This setup creates asynchrony, where brain structures, networks, and regions can become functionally disconnected and out of sync with each other. As a result of this disconnection, learning problems, memory issues, emotional, immune, sensory, social, and behavioral dysfunctions are bound to result. In the Functional Scalp Acupuncture model, an asynchronous brain is responsible for many of the physical, mental, emotional, and social difficulties related to the whole spectrum of neurobehavioral, neuropsychiatric, neurodegenerative, and autoimmune conditions. We can consider that they are all disorders related to cognitive, sensory, motor, and emotional regulation where the rhythm and timing are out of sync in one or more parts of the brain. They all are also disorders where inflammation is rampant. Contemporary acupuncturists need a comprehensive program that targets the primary problems - functional disconnection and inflammation. Lack of functional connectivity plus inflammation in our patient's brains results in many of the symptoms that present in our clinics. In light of what we now know, we can start to understand all disorders as asynchronous brain structures and networks that are churning out the neurophysiology that creates symptoms. The research can help us to become more astute at identifying symptoms that signify brain asynchrony in specific receiving and processing centers, e.g., from the midbrain, the thalamus, the basal ganglia, and somatosensory cortex, to limbic, sensory, and cognitive integration areas such as the insular cortex, dorsolateral prefrontal cortex, ventromedial PFC, and the orbitofrontal cortex. It can also help clue us in to brain network involvement, neurotransmitter imbalances, and synaptic impairment. In the FSA model, decreasing inflammation and improving the function of the prefrontal cortex, the somatosensory cortex, the motor cortex, and the association cortices, (as well as supporting functional connectivity to limbic structures), leads to brain integration and resolution of symptoms. The revolutionary import is that we can now consider depression, anxiety, schizophrenia, autism, ADHD, OCD, autoimmune, and Alzheimer's disease as brain asynchrony in need of balance.

Neurobiology of Brain Disorders

Neurobiology of Brain Disorders Book
Author : Michael J. Zigmond,Joseph T. Coyle,Lewis P. Rowland
Publisher : Elsevier
Release : 2014-12-03
ISBN : 0123982804
Language : En, Es, Fr & De

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Book Description :

Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases. Links basic, translational, and clinical research on disorders of the nervous system, creating a format for study that will accelerate disease prevention and treatment Covers a vast array of neurological disorders, including ADHD, Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson, Huntington, Alzheimer, OCD, PTSD, schizophrenia, depression, and pain Illustrated in full color Each chapter provides in-text summary points, special feature boxes, and research questions Provides an up-to-date synthesis of primary source material