Skip to main content

Chiral Analysis

In Order to Read Online or Download Chiral Analysis Full eBooks in PDF, EPUB, Tuebl and Mobi you need to create a Free account. Get any books you like and read everywhere you want. Fast Download Speed ~ Commercial & Ad Free. We cannot guarantee that every book is in the library!

Chiral Analysis

Chiral Analysis Book
Author : Kenneth W. Busch,Marianna A. Busch
Publisher : Elsevier
Release : 2011-10-13
ISBN : 9780080469287
Language : En, Es, Fr & De

GET BOOK

Book Description :

Chiral Analysis covers an important area of analytical chemistry of relevance to a wide variety of scientific professionals. The target audience is scientific professionals with an undergraduate background in chemistry or a related discipline, specifically organic chemists, researchers in drug discovery, pharmaceutical researchers involved with process analysis or combinatorial libraries, and graduate students in chemistry. Chapters have been written with the nonspecialist in mind so as to be self-contained. * Broad coverage - spectroscopic and separation methods covered in a single volume * Up-to-date and detailed review of the various techniques available and/or under development in this field * Contributions from leading experts in the field

Chiral Analysis

Chiral Analysis Book
Author : P.L. Polavarapu
Publisher : Elsevier
Release : 2018-05-30
ISBN : 0444640282
Language : En, Es, Fr & De

GET BOOK

Book Description :

Chiral Analysis: Advances in Spectroscopy, Chromatography and Emerging Methods, Second Edition covers an important area of analytical chemistry of relevance to a wide variety of scientific professionals, including chemistry graduate students, analytical chemists, organic chemists, professionals in the pharmaceutical industry, and others with an interest in chirality and chiral analysis. This thoroughly revised second edition covers several new, important areas of chiral analysis that have emerged since the first edition. Three of the new methods provide higher sensitivity than can be realized with the current methods and are expected to become mainstream applications: cavity based methods offer vastly higher sensitivity than conventional polarimetric methods, microwave chiral detection provides unsurpassed sensitivity for identifying diastereomers, and the rotating electric field method offers a competing new approach for the separation of enantiomers. Another topic, chirality in extraterrestrial life, has not been discussed in any other book and is important for understanding the origin of life. Offers the only book to cover both spectroscopic and separation methods in a single volume Provides an up-to-date and detailed review of the various techniques available, including new techniques that have emerged since the first edition Includes contributions from a range of leading experts in the field, now edited by award-winning chirality researcher Prasad Polavarapu

Capillary Electrophoresis in Chiral Analysis

Capillary Electrophoresis in Chiral Analysis Book
Author : Bezhan Chankvetadze
Publisher : John Wiley & Sons
Release : 1997-12-29
ISBN : 9780471974154
Language : En, Es, Fr & De

GET BOOK

Book Description :

Capillary Electrophoresis in Chiral Analysis Bezhan Chankvetadze Tbilisi State University, Republic of Georgia The application of capillary electrophoresis (CE) to the field of chiral analysis has exploded recently. The advantages of capillary electrophoresis - extremely high peak efficiency, excellent compatibility with biological samples, short analysis time, simplicity, versatility and low cost - are perfect for the accurate measurement of optical purity, increasingly important in the regulation-ruled pharmaceutical industry. Although there have been a number of books on capillary electrophoresis and chiral analysis separately, as yet there has been no dedicated monograph on the application of capillary electrophoresis to chiral analysis. This book bridges the gap. Capillary Electrophoresis in Chiral Analysis charts the evolution of chiral capillary electrophoresis and describes new types of chiral selectors and mechanistic aspects of chiral recognition. While on the one hand, it is an excellent introduction to newcomers, on the other, it is of practical use to experienced researchers in the field wishing to solve a particular separation problem. It includes an alphabetical list of chiral compounds resolved using CE with appropriate references, which any one working in the field will find invaluable.

Thin Layer Chromatography in Chiral Separations and Analysis

Thin Layer Chromatography in Chiral Separations and Analysis Book
Author : Teresa Kowalska,Joseph Sherma
Publisher : CRC Press
Release : 2007-06-22
ISBN : 0849343968
Language : En, Es, Fr & De

GET BOOK

Book Description :

Thin layer chromatography (TLC) is well suited for performing enantioseparations for research as well as larger-scale applications. A fast, inexpensive, and versatile separation technique, there are many practical considerations that contribute to its effectiveness. Thin Layer Chromatography in Chiral Separations and Analysis is the first bo

Analysis of Chiral Organic Molecules

Analysis of Chiral Organic Molecules Book
Author : Peter Schreier,Alexander Bernreuther,Manfred Huffer
Publisher : Walter de Gruyter
Release : 1995-01-01
ISBN : 3110867850
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Analysis of Chiral Organic Molecules book written by Peter Schreier,Alexander Bernreuther,Manfred Huffer, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Chiral Recognition in Separation Methods

Chiral Recognition in Separation Methods Book
Author : Alain Berthod
Publisher : Springer Science & Business Media
Release : 2010-06-16
ISBN : 9783642124457
Language : En, Es, Fr & De

GET BOOK

Book Description :

What drives a scientist to edit a book on a speci c scienti c subject such as chiral mechanisms in separation methods? Until December 2005, the journal Analytical Chemistry of the American Chemical Society (Washington, DC) had an A-page section that was dedicated to simple and clear presentations of the most recent te- niques or the state of the art in a particular eld or topic. The “A-page” section was prepared for a broad audience of chemists including industrial professionals, s- dents as well as academics looking for information outside their eld of expertise. 1 Daniel W. Armstrong, one of the editors of this journal and a twenty-year+ long friend, invited me to present my view on chiral recognition mechanisms in a simple and clear way in an “A-page” article. In 2006, the “A-page” section was maintained as the rst articles at the beginning of each rst bi-monthly issue but the pagination was no longer page distinguished from the regular research articles published by the journal. During the time between the invitation and the submission, the A-page section was integrated into the rest of the journal and the article appeared as (2006) Anal Chem (78):2093–2099.

Chiral Separation Techniques

Chiral Separation Techniques Book
Author : Ganapathy Subramanian
Publisher : John Wiley & Sons
Release : 2008-01-08
ISBN : 352761172X
Language : En, Es, Fr & De

GET BOOK

Book Description :

Thoroughly revised, with either entirely new or completely updated contents, this is a practical manual for the small and large-scale preparation of enantiomerically pure products. The result is a vital resource for meeting the highest purity standards in the manufacture of chiral pharmaceuticals, food additives and related compounds. All the approaches covered here are highly relevant to modern manufacturing and quality control schemes in the pharmaceutical and biotech industries, addressing the increasingly important issue of drug safety in view of tougher regulatory standards worldwide.

Chiral Separation Methods for Pharmaceutical and Biotechnological Products

Chiral Separation Methods for Pharmaceutical and Biotechnological Products Book
Author : Satinder Ahuja
Publisher : John Wiley & Sons
Release : 2011-03-31
ISBN : 9781118097755
Language : En, Es, Fr & De

GET BOOK

Book Description :

Discusses chiral separations and offers guidance for selectingthe optimum method for desired results Chiral separations represent the most intriguing and, by somemeasures, most difficultseparations of chemical compounds. Thisbook provides researchers and students an under-standing of chiralseparations and offers a convenient route to selecting the bestseparation method, saving considerable time and cost in productdevelopment. Considering chiral separations in the biotechnological andpharmaceutical industries, as well as for food applications, Dr.Ahuja provides insights into a broad range of topics. Opening witha broad overview of chiral separations, regulatory considerationsin drug product development, and basic issues in methoddevelopment, the book: Covers a variety of modern methods such as gas chromatography,high performance liquid chromatography, supercritical fluidchromatography, and capillary electrophoresis Deals with the impact of chirality on the biological activity ofsmall and large molecules Provides detailed information on useful chiral stationary phases(CSPs) for HPLC Includes handy information on selection of an appropriate CSP,including mechanistic studies Offers strategies for fast method development with HPLC, SFC,and CE Discusses preparatory methods utilized in the pharmaceuticalindustry With in-depth discussions of the current state of the field aswell as suggestions to assist future developments, ChiralSeparation Methods for Pharmaceutical and BiotechnologicalProducts is an essential text for laboratory investigators,managers, and regulators who are involved in chiral separations inthe pharmaceutical industry, as well as students preparing forcareers in these fields.

Chiral Pollutants

Chiral Pollutants Book
Author : Imran Ali,Hassan Y. Aboul-Enein
Publisher : John Wiley & Sons
Release : 2005-07-15
ISBN : 0470867817
Language : En, Es, Fr & De

GET BOOK

Book Description :

Today, among the various chiral discrimination methods, chromatography and capillary electrophoresis techniques have become powerful tools in environmental analysis. Therefore, there is a need to describe the art of the determination of the chiral pollutants in the environmental matrices. This book provides the complete information on the types of the chiral pollutants, their toxicities and methods of determination by chromatography and capillary electrophoresis.

Chiral Environmental Pollutants

Chiral Environmental Pollutants Book
Author : R. Kallenborn,H. Hühnerfuss
Publisher : Springer Science & Business Media
Release : 2001-01-18
ISBN : 9783540664239
Language : En, Es, Fr & De

GET BOOK

Book Description :

This monograph contains a survey on the role of chirality in ecotoxicological processes. The focus is on environmental trace analysis. Areas such as toxicology, ecotoxicology, synthetic chemistry, biology, and physics are also covered in detail in order to explain the different properties of enantiomers in environmental samples. This monograph delivers a comprehensive survey for environmental trace analysts, analytical chemists, ecotoxicologists, food scientists and experienced lab workers.

Chiral Chromatography

Chiral Chromatography Book
Author : Thomas E. Beesley,Raymond P. W. Scott
Publisher : John Wiley & Sons
Release : 1999-01-26
ISBN : 9780471974277
Language : En, Es, Fr & De

GET BOOK

Book Description :

Chiral Chromatography Thomas E. Beesley Advanced Separation Technologies Inc., Whippany, New Jersey, USA Raymond P. W. Scott Chemistry Department, Georgetown University, Washington DC, USA and Chemistry Department, Birkbeck College, University of London, UK Analytical techniques based on separation processes, such as chromatography and electrophoresis, are finding a growing range of applications in chemical, pharmaceutical and clinical laboratories. The Wiley Separation Science Series provides the analyst in these laboratories with well-focused books covering individual techniques, so that they can be applied more efficiently and effectively to contemporary analytical problems. The different enantiomers of a drug can exhibit widely different physiological activity in degree and nature. As a result, the separation and identification of enantiomers is now a very important analytical problem and chiral chromatography is the natural technique to apply to the resolution of such mixtures. Chiral Chromatography provides the reader with a basic understanding of the nature of chromatographic separations and relates the principles specifically to the separation of enantiomers. The following information is included: * chiral separations involving both gas and liquid chromatography * descriptions of the apparatus used for both techniques * detailed discussion on the retention mechanism that results in chiral selectivity * the structure and synthesis of a wide range of chirally active stationary phases used in both gas and liquid chromatography * preparative applications for large scale purification of enantiomers * applications of capillary electrophoresis and capillary electrochromatography. In addition to the above, a large number of examples of the separation of both commercially and physiologically interesting chiral mixtures are given, as is a detailed discussion on the mechanism of selectivity of each example. Thomas Beesley was founder and is the CEO for a leading manufacturer of chiral stationary phases and has published papers on TLC, HPLC and chiral separations involving cyclodextrins. He has also coauthored papers with Daniel W. Armstrong, an expert on modern cyclodextrin columns. Raymond Scott has worked in the field of separation science for over 40 years and has contributed extensively to the development of both gas and liquid chromatography publishing over 160 papers on the subjects.

A Practical Guide to Chiral Analysis

A Practical Guide to Chiral Analysis Book
Author : Louis (Pete) A. Silks, III
Publisher : Wiley
Release : 2015-08-24
ISBN : 9780470455500
Language : En, Es, Fr & De

GET BOOK

Book Description :

Written by an acclaimed expert in the field, A Practical Guide to Chiral Analysis provides an entry-level, user-friendly introduction to the subject. Highlighting common methods of chiral analysis used by the practitioner as well as recent advances, the text is destined to become the go-to source for analytical chemists, pharmaceutical scientists, and lab technicians when a chiral analytical process needs to be understood or performed. The author includes an entire chapter on the strategies of choosing the correct method chiral analysis method.

Chiral Separations by Liquid Chromatography

Chiral Separations by Liquid Chromatography Book
Author : Satinder Ahuja,American Chemical Society,American Chemical Society. Meeting
Publisher : Amer Chemical Society
Release : 1991
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

A definitive reference for researchers working on problems involving chirality. Presenting state-of-the-art information, this volume covers all the major modes of separation and offers contributions from the leading researchers who developed these techniques. Four chapters provide a detailed review of the commonly used columns: brush type, cyclodextrin, polysaccaride carbonate, and protein. Many of the papers focus on HPLC, a technique which is also ideally suited for large scale preparation of optical isomers. In addition, the volume provides significant discussion on the use of chiral discriminators or selectors.

Polarization analyzed Resonant X ray Scattering Study of Chiral Smectic C Variant Phases in Freely suspended Liquid crystal Films

Polarization analyzed Resonant X ray Scattering Study of Chiral Smectic C Variant Phases in Freely suspended Liquid crystal Films Book
Author : Peter Paul Mach
Publisher : Unknown
Release : 1999
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Polarization analyzed Resonant X ray Scattering Study of Chiral Smectic C Variant Phases in Freely suspended Liquid crystal Films book written by Peter Paul Mach, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Chromatographic Analysis of Pharmaceuticals

Chromatographic Analysis of Pharmaceuticals Book
Author : John A. Adamovics
Publisher : Marcel Dekker Incorporated
Release : 1990
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Chromatographic Analysis of Pharmaceuticals book written by John A. Adamovics, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Validation of Chiral Chromatographic Analysis of Drugs and Herbicides

Validation of Chiral Chromatographic Analysis of Drugs and Herbicides Book
Author : Hubert Pun Ho Che
Publisher : Unknown
Release : 1990
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Chromatographic enantioseparations were performed for the chiral study of some arylpropionate non-steroidal anti- inflammatory drugs (NSAID's) and chemically related phenoxypropionate herbicides. Employing different chromatographic approaches solved a variety of difficulties in the analysis of chiral substances. In comparing the use of a chiral stationary phase (CSP) for the direct resolution of enantiomeric compounds to pre - derivatisation approaches, it was noticed that there was little evidence of racemisation during derivatisation or kinetic resolution. A systematic investigation was devoted to certain problems encountered in the chiral analysis. The analysis of chiral acidic solutes was attempted by direct HPLC resolution on an alpha- acid glycoprotein (AGP) CSP. An alternative approach to direct resolution of chiral acidic compounds, the use of enantiomeric amide derivatives on a "Pirkle" ionic type HPLC - CSP, was studied. Another approach involved formation of diastereomeric amide derivatives using a chiral derivating reagent followed by separation on an achiral capillary GC column. Other approaches, such as TLC and peaks switching techniques, were also utilised.

Modern Derivatization Methods for Separation Science

Modern Derivatization Methods for Separation Science Book
Author : Toshimasa Toyo'oka
Publisher : John Wiley & Sons
Release : 1999
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Includes new derivatizing reagents not covered in similar book by Blau and Halket (Wiley 1993) and not found in any other books to date. A field of increasing importance and significance in separation science. Concentrates on synthesis of derivatives for HPLC and Capillary Electrophoresis, techniques of great interest in the pharmaceutical field.

Journal of analysis and its application

Journal of analysis and its application Book
Author : Anonim
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Journal of analysis and its application book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Differentiation of Chiral Compounds Using NMR Spectroscopy

Differentiation of Chiral Compounds Using NMR Spectroscopy Book
Author : Thomas J. Wenzel
Publisher : John Wiley & Sons
Release : 2018-07-11
ISBN : 1119323916
Language : En, Es, Fr & De

GET BOOK

Book Description :

An updated guide to the most current information available for determining how to use NMR spectroscopy to differentiate chiral compounds Differentiation of Chiral Compounds Using NMR Spectroscopy offers a thoroughly revised second edition to the essential volume that puts the focus on the chiral systems that are commercially available and have been widely vetted for use in NMR spectroscopy. The text covers a broad range of reagents that make it possible to determine the enantiomeric purity and assign the absolute configuration of many classes of compounds. Comprehensive in scope, the text describes the chiral NMR differentiating agents as derivatizing agents, solvating agents, metal-based reagents and liquid crystals and gels, and explains the range and types of compounds for which they can be used for analysis. New to this edition are the most recent findings in the field as well as the development of advanced NMR measurement techniques that allow for the simplification of complex spectra resulting in more readily identified enantiodifferentiation. This important resource: Includes the most recent coverage of a large range of compounds that can be analyzed using chiral NMR reagents Explores the use of chiral NMR reagents and explains their relationship to the stereochemistry of the analyzed molecules Offers the essential information needed to help decide which method is the best NMR method to apply to a class or molecules Contains experimental strategies for using the reagents that are likely to improve the quality of the results Differentiation of Chiral Compounds Using NMR Spectroscopy is a comprehensive guide designed for investigators planning to use NMR spectroscopy to determine enantiomeric purity or assign the absolute configuration of a compound.