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Chemosensory Transduction

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Chemosensory Transduction

Chemosensory Transduction Book
Author : Frank Zufall,Steven D. Munger
Publisher : Academic Press
Release : 2016-02-18
ISBN : 0128017864
Language : En, Es, Fr & De

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Book Description :

Written by leaders in the field of chemosensation, Chemosensory Transduction provides a comprehensive resource for understanding the molecular mechanisms that allow animals to detect their chemical world. The text focuses on mammals, but also includes several chapters on chemosensory transduction mechanisms in lower vertebrates and insects. This book examines transduction mechanisms in the olfactory, taste, and somatosensory (chemesthetic) systems as well as in a variety of internal sensors that are responsible for homeostatic regulation of the body. Chapters cover such topics as social odors in mammals, vertebrate and invertebrate olfactory receptors, peptide signaling in taste and gut nutrient sensing. Includes a foreword by preeminent olfactory scientist Stuart Firestein, Chair of Columbia University’s Department of Biological Sciences in New York, NY. Chemosensory Transduction describes state-of-the-art approaches and key findings related to the study of the chemical senses. Thus, it serves as the go-to reference for this subject for practicing scientists and students with backgrounds in sensory biology and/or neurobiology. The volume will also be valuable for industry researchers engaged in the design or testing of flavors, fragrances, foods and/or pharmaceuticals. Provides a comprehensive overview for all chemosensory transduction mechanisms Valuable for academics focused on sensory biology, neurobiology, and chemosensory transduction, as well as industry researchers in new flavor, fragrance, and food testing Edited by leading experts in the field of olfactory transduction Focuses on mammals, but lower vertebrates and invertebrate model systems are also included

Chemosensory Transduction in Dictyostelium Discoideum

Chemosensory Transduction in Dictyostelium Discoideum Book
Author : José Maria Mato de la Paz
Publisher : Unknown
Release : 1978
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Chemosensory Transduction in Dictyostelium Discoideum book written by José Maria Mato de la Paz, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Molecular Basis of Smell and Taste Transduction

The Molecular Basis of Smell and Taste Transduction Book
Author : Derek J. Chadwick,Joan Marsh,Jamie A. Goode
Publisher : John Wiley & Sons
Release : 2008-04-30
ISBN : 0470514523
Language : En, Es, Fr & De

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Book Description :

Recent application of the techniques of molecular biology and patch-clamp physiology has led to rapid advances in understanding the molecular events in chemosensory transduction. In this book, the latest results are presented and discussed by leading scientists. The extensive coverage encompasses many important topics, including mucous domains; microchemical heterogeneity in the mucociliary complex of the olfactory epithelium; membrane currents and mechanisms of olfactory transduction, and genetic and pathological taste variation.

Transduction Channels in Sensory Cells

Transduction Channels in Sensory Cells Book
Author : Stephan Frings,Jonathan Bradley
Publisher : John Wiley & Sons
Release : 2006-03-06
ISBN : 3527604979
Language : En, Es, Fr & De

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Book Description :

This is the first book to provide a molecular level explanation of how the senses work, linking molecular biology with sensory physiology to deduce the molecular mechanism of a key step in sensory signal generation. The editors have assembled expert authors from all fields of sensory physiology for an authoritative overview of the mechanisms of sensory signal transduction in both animals and plants. They systematically cover phototransduction, chemosensory transduction, mechanotransduction, temperature and pain perception, as well as specialized receptors for electrical and magnetic signals. Required reading for biologists, physiologists and medical researchers with an interest in sensory physiology.

A Study of Chemosensory Transduction in Paramecium Membrane and Axonemal Control of Ciliary Activity in a Protozoan Cell

A Study of Chemosensory Transduction in Paramecium Membrane and Axonemal Control of Ciliary Activity in a Protozoan Cell Book
Author : Anonim
Publisher : Unknown
Release : 1979
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Download A Study of Chemosensory Transduction in Paramecium Membrane and Axonemal Control of Ciliary Activity in a Protozoan Cell book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Membranes and Sensory Transduction

Membranes and Sensory Transduction Book
Author : Giuliano Colombetti,Francesco Lenci
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1461326753
Language : En, Es, Fr & De

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Book Description :

The main purpose of this book is to unify approaches and ideas in the field of aneural sensory transduction. This field has recently come to the attention of several research groups in various disciplines, and their number seems to be growing. Unfortunately, because of the diverse scientific backgrounds of the researchers in the field, the apparent heterogeneity of experimental techniques (i. e. , behavioral response analysis, sophisticated biochemical and genetic manipulations, conventional and pulsed laser spectroscopy) and theoretical approaches may be discouraging, for both the experienced worker and the new comer. Actually, this heterogeneity is more apparent than real, and unifying concepts, approaches, and ideas already exist, particularly with respect to all the questions concerning the role of membranes and their properties (such as ion permeability, electric potentials, and active transport) in the various steps of sensory perception and transduction processes. It is currently accepted that most, if not all, the fundamental facts in molecular sensory physiology of aneural organisms, be they chemosensory, photosensory, or geosensory, can ultimately be understood in terms of a few basic ideas. Each chapter of this book emphasizes and clarifies the role of mem brane properties and phenomena in the particular sensory response examined. Of course, in some cases, this task has been rather complex because of the limited amount of experimental data clearly supporting a membrane-based model of sensory transduction.

Control of Ciliary Activity in Paramecium

Control of Ciliary Activity in Paramecium Book
Author : Mike J. Doughty
Publisher : Unknown
Release : 1981
ISBN : 9780080284163
Language : En, Es, Fr & De

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Download Control of Ciliary Activity in Paramecium book written by Mike J. Doughty, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Camp Signaling in Chemosensory Transduction

Camp Signaling in Chemosensory Transduction Book
Author : Craig Dane Roberts
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

CAMP is a second messenger in a variety of chemosensory receptors, including taste buds and glucose-sensitive pancreatic beta-cells. cAMP is modulated during taste transduction, yet the significance of cAMP changes and the taste cell types in which they occur (Type I glial-like; Type II Receptor; Type III Presynaptic) remain unclear. I developed techniques to image real-time changes in intracellular cAMP in taste cells using genetically-encoded cAMP reporters. This FRET-based reporter permits one to measure single-cell cAMP levels with excellent spatial and temporal resolution (Zaccolo & Pozzan 2002, Science 295:1711). Using a biolistic approach I have transfected rat fungiform taste buds with cAMP reporter plasmids. Focal application of bitter tastant to living fungiform tastebuds in situ produced a decrease in [cAMP]i within individual taste receptor cells. These results are qualitatively similar to previous biochemical measurements from homogenized taste tissue (Yan et al. 2001, Am J Physiol Cell Physiol 280:C742) but are now allowing us to examine the cAMP response in individual, identified cells. I next explored the effect of elevating cAMP on calcium levels, using Fura-2 imaging of isolated mouse vallate taste buds. Elevating [cAMP]i in taste buds evoked calcium responses in presynaptic/Type III taste cells, which do not express GAD1. cAMP induced responses were generated by calcium influx. Using pharmacological antagonists, I determined that the calcium influx triggered by cAMP is through L-type calcium channels, whereas influx following depolarization is primarily through P/Q-type calcium channels. Consistent with these data, single cell RT-PCR showed that the L-type subunit (alpha 1C) was expressed primarily in GAD-negative Presynaptic cells, while the P/Q-type (alpha 1A) was expressed in all Presynaptic cells. Thus, cAMP may modulate the function of synapses in some taste cells. Finally, we have developed a mouse strain expressing a cAMP reporter in a tissue-specific and tetracycline-inducible manner. We crossed this mouse with another strain expressing tet-activator in beta cells of the pancreas. Such islets responded to increasing concentrations of glucose (5.5 to 35mM) with an increase in cAMP levels. The half maximum of 9mM glucose for the cAMP response corresponds well with reported glucose concentrations that elicit insulin release from whole islets. Stimulating pancreatic islets with glucose is known to drive calcium influx into beta-cells. When we simultaneously imaged both second messengers, we found that cAMP changes precede and are independent of calcium changes. In conclusion, these studies have outlined novel potential functions for cAMP signaling in the transduction of both primary tastant and plasma glucose information. In addition, the flexibility of the tet-system will enable cAMP reporter expression in numerous cell types, including those which mediate gustatory transduction.

Genetics of Chemosensory Transduction

Genetics of Chemosensory Transduction Book
Author : Anonim
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Analysis of Daf 11 a Transmembrane Guanylyl Cyclase that Mediates Chemosensory Transduction in C Elegans

Analysis of Daf 11  a Transmembrane Guanylyl Cyclase that Mediates Chemosensory Transduction in C  Elegans Book
Author : Deborah Ann Birnby
Publisher : Unknown
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Download Analysis of Daf 11 a Transmembrane Guanylyl Cyclase that Mediates Chemosensory Transduction in C Elegans book written by Deborah Ann Birnby, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Chemosensory Transduction in Paramecium

Chemosensory Transduction in Paramecium Book
Author : Ashley P. Kurtz
Publisher : Unknown
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Chemosensory Transduction in Paramecium book written by Ashley P. Kurtz, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Fish Chemoreception

Fish Chemoreception Book
Author : T.J. Hara
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 9401123322
Language : En, Es, Fr & De

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Book Description :

This book describes in general how the chemosensory systems of fish function at various levels. In many ways, fish are typical vertebrates differing only slightly from other vertebrates including humans. In other ways, their aquatic environment imposes strict requirements or offers unique opportunities which have resulted in some unusual functions having no counterpart in higher vertebrates. This new volume is necessitated by advances in many vital areas as the field of chemical senses continues to grow at a rapid pace. Most significant is the application of the contemporary electrophysiological technique of patch-clamping, recognition of a second messenger system in chemosensory transduction processes and the identification of hormonal pheromones in fish reproductive behaviour. The last major synthesis of our knowledge about fish chemoreception, Chemoreception in Fishes, was published ten years ago (Elsevier, Amsterdam, 1982). In that volume four aspects of fish chemoreception, Le. morphology of the peripheral chemoreceptors. primary sensory processes, roles in behaviour, and its interactions with environment, were discussed. This book is intended to be helpful to students, scientists and aquacul turists not only as a source book but also as a textbook on chemical senses.

Studies of Chemosensory Signal Transduction in Caenorhabditis Elegans

Studies of Chemosensory Signal Transduction in Caenorhabditis Elegans Book
Author : Kayvan Roayaie
Publisher : Unknown
Release : 1996
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Studies of Chemosensory Signal Transduction in Caenorhabditis Elegans book written by Kayvan Roayaie, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Sensory Perception and Transduction in Aneural Organisms

Sensory Perception and Transduction in Aneural Organisms Book
Author : Giuliano Colombetti,Francesco Lenci,Pill-Soon Song
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1461324971
Language : En, Es, Fr & De

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Book Description :

This book is based on the lectures given at the NATO Advanced Study Institute on "Sensory Perception and Transduction in Aneural Organisms" held in Volterra (Pisa. Italy) from the third to the fourteenth of September. 1984. The Advanced Study Institute was planned as a high level course dealing with several aspects and problems of sensory perception and transduction of diverse environmental stimuli in aneural organisms. Scientists from different fields and cultural backgrounds were present at the meeting. both as lecturers and as students. The lectures and the discussions that followed represented a well integrated interdisci plinary approach to the questions considered. At the end of the Advanced Study Institute course. it was quite clear that. notwith standing the apparent heterogeneity of the topics dealt with. unifying concepts and ideas already existed, among the most important being the role of membranes and their physicochemical properties. All this should be reflected in the content of this book. We gratefully acknowledge the financial sponsorship of the Scientific Affairs Division of NATO (Brussels), that made both the Advanced Study Institute on "Sensory Perception and Transduction in Aneural Organisms" and this book possible. Finally. we are also indebted to Ms. Pat Parham Morgan who expertly retyped all the chapters of the book and Ms. Leslie Schmidt of Plenum Publishing Co. provided us valuable advice and suggestions on the preparation of this book. G. Colombetti F. Lenci P. S.

Olfaction and Taste XI

Olfaction and Taste XI Book
Author : Kenzo Kurihara,Noriyo Suzuki,Hisashi Ogawa
Publisher : Springer Science & Business Media
Release : 2013-11-11
ISBN : 4431683550
Language : En, Es, Fr & De

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Book Description :

In this compendium of current studies on olfaction and taste - the most comprehensive yet to appear in this series - the chemical senses are elucidated from points of view ranging from anatomy, electrophysiology, molecular biology (especially chemoreceptor gene cloning), biochemistry, and psychophysics to the latest clinical and technological applications of chemosensory research. Specific topics include the structure and function of the tastebud and olfactory epithelium; the genetics and mechanisms of olfactory and taste transduction; the chemistry and function of flavor compounds; the psychophysics of taste and olfaction in daily human life; the brain mechanisms of coding, learning, and memory in olfaction and taste; the clinical assessment of taste and olfaction with special reference to aging and disorders; noninvasive measurements of human olfactory and taste responses for therapeutic purposes; artifical sensing devices; chemoreception in aquatic organisms and other species; and chemosensory transduction in insects. With its multidisciplinary approach, this volume will be an invaluable source of information not only for researchers, clinicians, and students but also for technologists in fields such as artificial sensing, perfumery, brewery, food chemistry, aquafarming, and agriculture.

The Molecular Basis of Smell and Taste Transduction

The Molecular Basis of Smell and Taste Transduction Book
Author : CIBA Foundation Symposium
Publisher : Wiley
Release : 1993-12-28
ISBN : 9780471939467
Language : En, Es, Fr & De

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Book Description :

Recent application of the techniques of molecular biology and patch-clamp physiology has led to rapid advances in understanding the molecular events in chemosensory transduction. In this book, the latest results are presented and discussed by leading scientists. The extensive coverage encompasses many important topics, including mucous domains; microchemical heterogeneity in the mucociliary complex of the olfactory epithelium; membrane currents and mechanisms of olfactory transduction, and genetic and pathological taste variation.

Signal Transduction

Signal Transduction Book
Author : Gerard Meurant
Publisher : Academic Press
Release : 2012-12-02
ISBN : 0323139124
Language : En, Es, Fr & De

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Book Description :

An explosion of information has occurred over the past few years in the field of signal transduction. As information form prokaryotes and eukaryotes has accumulated, it has become evident that diverse sensory systems share common mechanistic themes. This volume reviews our the current knowledge of molecular mechanisms for sensory transduction in a variety of microbial systems, as well as elegant work done in nematodes and Drosophila. Signal Transduction is intended for both researchers studying microbial systems and investigators and students of signal transduction in more complex organisms, who can learn from the paradigms and mechanisms conserved between prokaryotes and eukaryotes.

Chemosensory Information Processing

Chemosensory Information Processing Book
Author : Detlev Schild
Publisher : Springer Science & Business Media
Release : 2013-06-29
ISBN : 364275127X
Language : En, Es, Fr & De

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Book Description :

In July 1989 a symposium was held at the Physiology Department of the Georg August University, G6ttingen, on the physiological, biophysical, biochemical, and technical principles of the coding of chemical substances both in nervous systems and artificial devices. This book is the collection of the papers presented at that meeting. Biological and artificial systems for odor coding both have in common that the stimulus selectivity of the receptor cells (sensors) is usually very poor, and the mechanisms which determine selectivity and sensitivity are largely unknown. However, a poor selectivity allows the coding of an enormous number of stimuli by combinations of receptor activities. In the field of chemosensory information coding there are thus two major problems: the function of the receptors and the network that processes and evaluates the primary information of the sensors. Accordingly, this volume has three parts: sensors, the network following the sensors, and the coding in this network. The expert secretarial assistance of M. Holtmann in preparing the camera-ready manuscript is gratefully acknowledged. D. Schild G6ttingen, August 1989 CONTENTS l. Response of olfactory receptor cells, isolated and in situ, to low concentrations of odorants 1 Stephan Frings, Bernd Lindemann 2. Excitation and adaptation of frog olfactory receptor neurones upon stimulation with second messengers and natural odorants 9 D. Schild, J. A. DeSimone, S. Hellwig 3. Receptor selectivity and dimensionality of odours at the stage of the olfactory receptor cells 21 GiJJes Sicard 4.

Molecular Mechanisms of Signal Transduction in Chemosensory Neurons of Mice

Molecular Mechanisms of Signal Transduction in Chemosensory Neurons of Mice Book
Author : Daniela Brunert
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Download Molecular Mechanisms of Signal Transduction in Chemosensory Neurons of Mice book written by Daniela Brunert, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Methods in Chemosensory Research

Methods in Chemosensory Research Book
Author : Sidney A. Simon,Miguel A. L. Nicolelis
Publisher : CRC Press
Release : 2001-09-26
ISBN : 1420038729
Language : En, Es, Fr & De

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Book Description :

Written by world experts in the field of neuronal chemoreception, Methods in Chemosensory Research describes new molecular, electrophysiological, genetic, behavioral, psychophysical, and imaging techniques that have recently been adapted to investigate the basic neuronal mechanisms underlying chemoreception: taste, olfaction and chemical-induced irritation. This unique book includes a wide variety of new and innovative imaging methods, electrophysiological methods, methods to investigate development, and various aspects of behavioral testing. Covering the entire spectrum of chemoreception, each section not only describes what information can be obtained by using each method, but also shows how to apply each method to obtain reliable results. The book presents a comprehensive view of how the brain uses information about chemical stimuli that interact with receptors in the nose and tongue. Methods in Chemosensory Research gives you the new tools to learn how chemicals affect activity from the genetic to the behavioral levels.