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Chelation Therapy In The Treatment Of Metal Intoxication

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Chelation Therapy in the Treatment of Metal Intoxication

Chelation Therapy in the Treatment of Metal Intoxication Book
Author : Jan Aaseth,Guido Crisponi,Ole Anderson
Publisher : Academic Press
Release : 2016-04-18
ISBN : 0128030739
Language : En, Es, Fr & De

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Book Description :

Chelation Therapy in the Treatment of Metal Intoxication presents a practical guide to the use of chelation therapy, from its basic chemistry, to available chelating antidotes, and the application of chelating agents. Several metals have long been known to be toxic to humans, and continue to pose great difficulty to treat. These challenges pose particular problems in industrial settings, with lead smelting known to be associated with hemopoietic alterations and paralyses, and the inhalation of mercury vapor in mercury mining being extremely detrimental to the central nervous system. Clinical experience has demonstrated that acute and chronic human intoxications with a range of metals can be treated efficiently by administration of chelating agents. Chelation Therapy in the Treatment of Metal Intoxication describes the chemical and biological principles of chelation in the treatment of these toxic metal compounds, including new chelators such as meso-2,3-dimercaptosuccinic acid (DMSA) and D,L-2,3-dimercapto-1-propanesulfonic acid (DMPS). Presents all the current findings on the potential for chelation as a therapy for metal intoxication Presents practical guidelines for selecting the most appropriate chelating agent Includes coverage on radionuclide exposure and metal storage diseases Describes the chemical and biological principles of chelation in the treatment of toxic metal compounds

Evidence Based Clinical Chelation

Evidence Based Clinical Chelation Book
Author : Dr. Eleonore Blaurock-Busch, PhD,Dr. Swaran J.S. Flora, PhD,Dr. Ebrahim Sulaiman, MD
Publisher : BoD – Books on Demand
Release : 2020-06-02
ISBN : 3750428670
Language : En, Es, Fr & De

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Book Description :

This is an easy-to-read manual about chelation therapy. It contains specific protocols for the treatment of chronic metal overexposure, all of which are evidence-based, aiding the inexperienced and the experienced therapist in selecting the optimal chelating agent for the metal(s) in question. Expert chemists and chelation therapists have contributed invaluable knowledge and experience to this book. Most importantly, this is not a book promoting personal views or preferences. In fact, the information presents and explains different approaches, and allows the reader to draw his own conclusion. All the protocols listed have been modified for the treatment of chronic metal intoxication, included are oral and intravenous treatment plans. The authors explain in simple terms how a chelating agent ́s bioavailability affects metal binding and how various protocols such as the Cutler Protocol affect the detoxification process, why DMPS binds mercury and which chelators are useful for the detoxification of certain organ system. Also discussed is the importance and effect of treatment pauses. Diagnostic tests are discussed, and which are useful under certain conditions. Shown are tables comparing the average metal binding ability of the various EDTAs, DMPS, DMSA and other chelating agents. Detailed information explains which chelator binds which metal and why, all of which aids the therapist in finding optimal treatment schedules. Novel chelating agents are presented such as MIADMSA, a new oral chelator specifically designed for arsenic intoxication, or how natural Pectin may be used an alternative for gadolinium intoxication, which metals are bound by lipoic acid and why a slightly alkaline environment supports metal binding, even preventing the often-feared metal redistribution. All in all, this evidence-based chelation "cookbook" should be in medical libraries and on the bookshelf of every physician treating environmental disease.

Biomedical Applications of Metals

Biomedical Applications of Metals Book
Author : Mahendra Rai,Avinash P. Ingle,Serenella Medici
Publisher : Springer
Release : 2018-02-24
ISBN : 3319748149
Language : En, Es, Fr & De

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Book Description :

Focused more specifically on the recent advances in applications of various metals and their complexes used in biomedicine, particularly in the diagnosis and treatment of chronic diseases. The editors give equal importance to other key aspects such as toxicological issues and safety concerns. The application of metals in the biomedical field is highly interdisciplinary and has a broad appeal across all biomedical specialties. Biomedical Applications of Metals is particularly focused on covering the role of metals in medicine and the development of novel therapeutic products and solutions in the form of alternative medicines, and some topics on Indian traditional medicine i.e., “Ayurveda”. In Section I, the book discusses the role of metals in medicines and include chapters on nanoparticles, noble metals, medical devices, copper. selenium, silver, and microbial pathogens; while Section II includes topics on metals toxicity including heavy metals, carcinogens, cancer therapy, Bhasma’s and chelating agents used in Ayurveda, and biochemical and molecular targets including actions of metals. These new and emerging concepts of applications of metals in medicine, their crucial role in management of microbial resistance, and their use in the treatment of various chronic diseases is essential information for toxicologists, and clinical and biomedical researchers.

Applications of Biodegradable and Bio Based Polymers for Human Health and a Cleaner Environment

Applications of Biodegradable and Bio Based Polymers for Human Health and a Cleaner Environment Book
Author : Iuliana Stoica,Omari Mukbaniani,Neha Kanwar Rawat,A. K. Haghi
Publisher : CRC Press
Release : 2021-12-23
ISBN : 1000345637
Language : En, Es, Fr & De

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Book Description :

The world faces significant challenges as the population and consumption continue to grow while nonrenewable fossil fuels and other raw materials are depleted at ever-increasing rates. This informative volume provides a technical approach to address these issues using green design and analysis. It takes an interdisciplinary look at concepts that can be applied across engineering disciplines in the development of products, processes, and systems to minimize environmental impacts across all life cycle phases. Topics include polymers for pollutant removal, wood-based biopolymers, bio-based polymers for drug formulations, biomaterial-based medical implants, biodegradabilty of biopolymer materials, bio-based polymers for food packaging applications, biodegradable polymers for tissue engineering applications, and more.

Integrative Medicine E Book

Integrative Medicine   E Book Book
Author : David Rakel
Publisher : Elsevier Health Sciences
Release : 2017-03-21
ISBN : 0323496172
Language : En, Es, Fr & De

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Book Description :

Stay on the cutting edge of today’s most promising trends in complementary and alternative medical treatments with Dr. David Rakel’s Integrative Medicine, 4th Edition. Written by physicians who are experts in both traditional and integrative medicine, this highly regarded, evidence-based reference covers therapies such as botanicals, supplements, mind-body, lifestyle choices, nutrition, exercise, spirituality, and more. Integrative Medicine, 4th Edition uses a clinical, disease-oriented approach, offering practical guidance for reducing costs and improving patient care. Helps you safely and effectively incorporate complementary and alternative therapies into your everyday practice, while focusing on prevention and wellness for a better quality of life. Uses the reliable SORT method (Strength of Recommendation Taxonomy) to provide evidence-based ratings, grading both the evidence and the relative potential harm. Explains how to make the best use of integrative medicine and the mechanisms by which these therapeutic modalities work, keeping you at the forefront of the trend toward integrative health care. Includes 13 brand-new chapters, covering hot topics such as personalized medicine, MTHFR mutation, food allergy and intolerance, the gut-immune influence on systemic inflammation and disease, chelation therapy, testosterone deficiency, adrenal fatigue, and much more. Features more than 100 significantly revised chapters and hundreds of new figures and tables throughout.

Advances in Analytical Techniques and Methodology for Chemical Speciation Study

Advances in Analytical Techniques and Methodology for Chemical Speciation Study Book
Author : Ottavia Giuffrè,Carlos Rey-Castro,Anna Napoli
Publisher : Frontiers Media SA
Release : 2021-07-05
ISBN : 2889669785
Language : En, Es, Fr & De

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Book Description :

Download Advances in Analytical Techniques and Methodology for Chemical Speciation Study book written by Ottavia Giuffrè,Carlos Rey-Castro,Anna Napoli, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Metal Chelation in Medicine

Metal Chelation in Medicine Book
Author : Robert R Crichton,Roberta J Ward,Robert C Hider
Publisher : Royal Society of Chemistry
Release : 2016-10-18
ISBN : 1782623892
Language : En, Es, Fr & De

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Book Description :

Metal chelators are emerging as versatile tool with many medical applications. Their versatility allows them to be used in chelation therapy for treating diseases caused by toxic and heavy metal poisoning, chelating agents are capable of binding to toxic metal ions to form complex structures which are easily excreted from the body removing them from intracellular or extracellular spaces. In addition, metal chelators can also be applied as contrast agents in MRI scanning. Metal Chelation in Medicine provides a clear and timely perspective on the role of chelating agents in the management of metal intoxications and storage diseases. Written by leaders in the field of chelators, this publication is at the cutting-edge of the subject. It covers a broad range of topics such as the use of metal chelators in non-invasive assessment of brain iron overload, and the treatment of systemic iron overload and neurodegenerative diseases. As such it is particularly valuable to clinicians treating metal poisonings and metal storage diseases. However, it is also a useful text for researchers, industry professionals and university students with a specific interest in medicinal chemistry, chelation, metal ions, imaging and non-invasive techniques.

Reproductive and Developmental Toxicology

Reproductive and Developmental Toxicology Book
Author : Ramesh C. Gupta
Publisher : Academic Press
Release : 2017-03-24
ISBN : 0128042400
Language : En, Es, Fr & De

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Book Description :

Reproductive and Developmental Toxicology, Second Edition, is a comprehensive and authoritative resource that provides the latest literature on this complex subject with a primary focus on three core components—parent, placenta, and fetus—and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics, including nanoparticles and radiation, gases and solvents, smoking, alcohol and drug abuse, and metals, amongst others. With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages, also including discussions on reproductive and developmental toxicity in domestic animals, fish, and wildlife. Completely revised and updated to include the most recent developments in the field, the book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists, and teratologists from academia, industry, and regulatory agencies. Provides a complete, up-to-date, integrated source of information on the key risk stages during reproduction and development Includes new chapters covering significant developments, such as dose-response assessment for developmental toxicity, juvenile toxicity, and neural tube defects, as well as emerging science, such as stem cell application, toxicoproteomics, metabolomics, endocrine disruption, surveillance and regulatory considerations, and risk assessment Offers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis

Handbook of Neurological Therapy

Handbook of Neurological Therapy Book
Author : Carlo Colosimo,Antonio Gil-Nagel,Nils Erik Gilhus,Alan Rapoport,Olajide Williams
Publisher : Oxford University Press
Release : 2014-12-08
ISBN : 0199370206
Language : En, Es, Fr & De

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Book Description :

This is a practical book on neurological therapy. It is aimed at giving concise and updated answers to busy practicing clinicians in the clinic, ward, or emergency department. An evidence-based approach is used, but when there is no evidence or the data are inconclusive, an expert opinion is always given in order to meet the expectations of the reader. All neurological conditions, common and less common, are discussed; each chapter has a similar format, and contains an initial brief introduction on the epidemiology and clinical features of each disease. The therapy is then discussed, including pharmacological and non-pharmacological, with wide use of Tables & Figures. Flowcharts are also included in most of the chapters.

Pharmacological Perspectives of Toxic Chemicals and Their Antidotes

Pharmacological Perspectives of Toxic Chemicals and Their Antidotes Book
Author : S.J.S. Flora,James A. Romano,Steven I. Baskin,K. Sekhar
Publisher : Springer Science & Business Media
Release : 2004-09-10
ISBN : 9783540223788
Language : En, Es, Fr & De

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Book Description :

This is the first book on toxic chemicals that puts a special focus on chemical weapons and bioterrorism. Leading experts provide up-to-date pharmacological and toxicological information on chemical warfare agents, industrial chemicals, environmental toxins, metalloid and an array of miscellaneous agents including their mechanism of toxicity. Also discussed are a number of antidotes, which are being used, or currently being investigated, for the treatments of the common toxicants.

Gentle Detox

Gentle Detox Book
Author : Dr. Eleonore Blaurock-Busch PhD
Publisher : BoD – Books on Demand
Release : 2015-05-29
ISBN : 3734788196
Language : En, Es, Fr & De

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Book Description :

In the last decades, toxic metal syndromes have been described. Chronic overexposure to lead, mercury and other potentially toxic metals can affect body and brain, causing a wide variety of diseases, including skin and heart problems, contributing to Alzheimer, cancer and depression. International research has accumulated a large body of evidence linking chronic disease to environmental problems and some of it is listed here. Today, doctors and patients alike are more concerned about the diagnosis and treatment of chronic metal exposure and with this booklet we help them through the jungle of information. We explain what diagnostic tests are useful, and why and how the individual genetic make-up predisposes people to accumulate metals, where toxins are hidden. Medicine utilizes synthetic agents to detoxify acute and chronic metal intoxication. However, such chemical treatment may not be appropriate for sensitive patients, the very young or elderly. Nature has provided us with nutrients that are similarly capable of ‘chelating’ metals and this book explains not only the toxicity of metals, which symptoms they may cause or which organ systems they affect, nature also provides nutritional alternatives to synthetic chelation. We explain how natural detoxifying agents work, and provide nutritional self-treatment protocols. Nutritional detox requires more recovery and healing time. When it comes to chronic metal exposure, we need to admit that our organ systems did not get overburdened in one week or month. The body gradually adjusted to toxins, and it will appreciate a gradual and gentle elimination of the burdensome load so natural healing can take place. Reading The Gentle Detox leads the reader on to the safe road of natural detoxification.

Evidence Based Clinical Chelation

Evidence Based Clinical Chelation Book
Author : Dr. Eleonore Blaurock-Busch, PhD,Dr. Swaran J.S. Flora, PhD,Dr. Ebrahim Sulaiman, MD
Publisher : BoD – Books on Demand
Release : 2020-06-24
ISBN : 3750458103
Language : En, Es, Fr & De

GET BOOK

Book Description :

This is an easy-to-read manual about chelation therapy. It contains specific protocols for the treatment of chronic metal overexposure, all of which are evidence-based, aiding the inexperienced and the experienced therapist in selecting the optimal chelating agent for the metal(s) in question. Expert chemists and chelation therapists have contributed invaluable knowledge and experience to this book. Most importantly, this is not a book promoting personal views or preferences. In fact, the information presents and explains different approaches, and allows the reader to draw his own conclusion. All the protocols listed have been modified for the treatment of chronic metal intoxication, included are oral and intravenous treatment plans. The authors explain in simple terms how a chelating agent ́s bioavailability affects metal binding and how various protocols such as the Cutler Protocol affect the detoxification process, why DMPS binds mercury and which chelators are useful for the detoxification of certain organ system. Also discussed is the importance and effect of treatment pauses. Diagnostic tests are discussed, and which are useful under certain conditions. Shown are tables comparing the average metal binding ability of the various EDTAs, DMPS, DMSA and other chelating agents. Detailed information explains which chelator binds which metal and why, all of which aids the therapist in finding optimal treatment schedules. Novel chelating agents are presented such as MIADMSA, a new oral chelator specifically designed for arsenic intoxication, or how natural Pectin may be used an alternative for gadolinium intoxication, which metals are bound by lipoic acid and why a slightly alkaline environment supports metal binding, even preventing the often-feared metal redistribution. All in all, this evidence-based chelation "cookbook" should be in medical libraries and on the bookshelf of every physician treating environmental disease.

Issues in Environment Health and Pollution 2011 Edition

Issues in Environment  Health  and Pollution  2011 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-01-09
ISBN : 146496436X
Language : En, Es, Fr & De

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Book Description :

Issues in Environment, Health, and Pollution: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Environment, Health, and Pollution. The editors have built Issues in Environment, Health, and Pollution: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Environment, Health, and Pollution in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Environment, Health, and Pollution: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Trace Elements Medicine and Chelation Therapy

Trace Elements Medicine and Chelation Therapy Book
Author : David R Williams,David M Taylor
Publisher : Royal Society of Chemistry
Release : 2007-10-31
ISBN : 1847552196
Language : En, Es, Fr & De

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Book Description :

This book discusses, in relatively simple language, the importance of even minute amounts of certain trace elements for the protection of human health and how insufficiency or excess may produce serious diseases. It also examines the use of metal chelators in the treatment of such diseases.

Environmental Health Perspectives

Environmental Health Perspectives Book
Author : Anonim
Publisher : Unknown
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Environmental Health Perspectives book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Medicinal Applications of Coordination Chemistry

Medicinal Applications of Coordination Chemistry Book
Author : Chris J. Jones,John Thornback
Publisher : Royal Society of Chemistry
Release : 2007
ISBN : 0854045961
Language : En, Es, Fr & De

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Book Description :

Metals in pharmaceuticals have played an increasingly important role in medicine over the last century, particularly in cancer therapy and diagnostic imaging methods. Medicinal Applications of Coordination Chemistry focuses on the role that transition metals play in clinical applications. Medicinal Applications of Coordination Chemistry begins with a brief historical review and an introduction to the chemistry of d- and f- block metals. Subsequent sections discuss metallodrugs for a number of different applications, the design of new drugs and the relationship between structure and function. Key sections include diagnostic applications of metal compounds in anatomical and functional imaging, and therapeutic applications of metals compounds. This book is ideal for researchers in academia and industry and comes complete with examples of real life applications.

Pharmacology

Pharmacology Book
Author : Michelle A. Clark,Richard A. Harvey,Richard Finkel,Jose A. Rey,Karen Whalen
Publisher : Lippincott Williams & Wilkins
Release : 2011-12-15
ISBN : 1451113145
Language : En, Es, Fr & De

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Book Description :

Lippincott's Illustrated Reviews: Pharmacology, Fifth Edition enables rapid review and assimilation of complex information and focuses on the essentials of medical pharmacology. Clear, sequential pictures present mechanisms of action and actually show, rather than tell, students how drugs work. This book features a signature outline format with more than 500 full-color illustrations and cross-references to other volumes in this bestselling, student-oriented series.

Immune System Diseases Advances in Research and Treatment 2012 Edition

Immune System Diseases   Advances in Research and Treatment  2012 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-12-26
ISBN : 1481603469
Language : En, Es, Fr & De

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Book Description :

Immune System Diseases—Advances in Research and Treatment: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Immune System Diseases. The editors have built Immune System Diseases—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Immune System Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Immune System Diseases—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

A Critical Review of EDTA Chelation Therapy in the Treatment of Occlusive Atherosclerotic Vascular Disease

A Critical Review of EDTA Chelation Therapy in the Treatment of Occlusive Atherosclerotic Vascular Disease Book
Author : Stephen F. Olmstead
Publisher : Mwmc Foundation
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download A Critical Review of EDTA Chelation Therapy in the Treatment of Occlusive Atherosclerotic Vascular Disease book written by Stephen F. Olmstead, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Neurology Review for Psychiatrists

Neurology Review for Psychiatrists Book
Author : Sean I. Savitz,Michael Ronthal
Publisher : Lippincott Williams & Wilkins
Release : 2008-11-01
ISBN : 9780781766661
Language : En, Es, Fr & De

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Book Description :

This concise review of neurology is an excellent study aid for psychiatry residents preparing for their annual in-service exam (PRITE) and written psychiatry board exam, as well as for practicing psychiatrists preparing for recertification exams. Succinct chapters written by expert authors address the essential points of diagnosis and management of a wide variety of neurological problems, with special emphasis on psychiatric aspects. Key Points are included in each chapter for rapid review.