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Characterization Of Nanomaterials In Complex Environmental And Biological Media

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Characterization of Nanomaterials in Complex Environmental and Biological Media

Characterization of Nanomaterials in Complex Environmental and Biological Media Book
Author : Anonim
Publisher : Elsevier
Release : 2015-06-01
ISBN : 0080999506
Language : En, Es, Fr & De

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Book Description :

Characterization of Nanomaterials in Complex Environmental and Biological Media covers the novel properties of nanomaterials and their applications to consumer products and industrial processes. The book fills the growing gap in this challenging area, bringing together disparate strands in chemistry, physics, biology, and other relevant disciplines. It provides an overview on nanotechnology, nanomaterials, nano(eco)toxicology, and nanomaterial characterization, focusing on the characterization of a range of nanomaterial physicochemical properties of relevance to environmental and toxicological studies and their available analytical techniques. Readers will find a multidisciplinary approach that provides highly skilled scientists, engineers, and technicians with the tools they need to understand and interpret complicated sets of data obtained through sophisticated analytical techniques. Addresses the requirements, challenges, and solutions for nanomaterial characterization in environmentally complex media Focuses on technique limitations, appropriate data collection, data interpretation, and analysis Aids in understanding and comparing nanomaterial characterization data reported in the literature using different analytical tools Includes case studies of characterization relevant complex media to enhance understanding

Environmental and Safety Impacts of Nanotechnology

Environmental and Safety Impacts of Nanotechnology Book
Author : United States. Congress. House. Committee on Science
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Environmental and Safety Impacts of Nanotechnology book written by United States. Congress. House. Committee on Science, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Characterization of Nanoparticles

Characterization of Nanoparticles Book
Author : Wolfgang Unger,Ing. V. -D. Hodoroaba,Alex Shard
Publisher : Unknown
Release : 2019-09-30
ISBN : 0128141824
Language : En, Es, Fr & De

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Book Description :

Characterization of Nanoparticles: Measurement Processes for Nanoparticles surveys this fast growing field, including established methods for the physical and chemical characterization of nanoparticles. The book focuses on sample preparation issues (including potential pitfalls), with measurement procedures described in detail. In addition, the book explores data reduction, including the quantitative evaluation of the final result and its uncertainty of measurement. The results of published inter-laboratory comparisons are referred to, along with the availability of reference materials necessary for instrument calibration and method validation. The application of these methods are illustrated with practical examples on what is routine and what remains a challenge. In addition, this book summarizes promising methods still under development and analyzes the need for complementary methods to enhance the quality of nanoparticle characterization with solutions already in operation. Helps readers decide which nanocharacterization method is best for each measurement problem, including limitations, advantages and disadvantages Shows which nanocharacterization methods are best for different classes of nanomaterial Demonstrates the practical use of a method based on selected case studies

Biomedical Application of Nanoparticles

Biomedical Application of Nanoparticles Book
Author : Bertrand Henri Rihn
Publisher : CRC Press
Release : 2017-09-05
ISBN : 1498750028
Language : En, Es, Fr & De

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Book Description :

Biomedical Application of Nanoparticles explores nanoparticles, their chemical and physicals properties, and how they interact in biological systems with proteins, immune system and targeted cells. Risk assessment of nanoparticles for human is described, including: cellular paradigms, transcriptomics and toxicogenomics. Finally, the applications of nanoparticles in medicine and antioxidant regenerative therapeutics are presented in several chapters with emphasis on how nanoparticles enhance transport of drugs across biological membrane barriers and therefore may enhance drug bioavailability.

Environmental Nanotechnology Applications and Impacts of Nanomaterials Second Edition

Environmental Nanotechnology  Applications and Impacts of Nanomaterials  Second Edition Book
Author : Mark Wiesner,Jean-Yves Bottero
Publisher : McGraw Hill Professional
Release : 2016-10-14
ISBN : 0071828451
Language : En, Es, Fr & De

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Book Description :

Extensively revised and featuring new material, this timely, advanced resource covers the impacts of nanomaterials on organisms and ecosystems and their applications within industry. Cowritten by leaders of two of the most prominent research groups in the world considering the effects of nanomaterials on the environment, the second edition of Environmental Nanotechnology addresses the cutting-edge advances in this area. There is now much more known about the impacts of nanomaterials on organisms and ecosystems. Methods have been developed where there were few accepted procedures in the past. Thinking has evolved to consider the life cycle effects of nanomaterial production, and tools for risk forecasting are now under development. There has also been some experience among academics in using this book as the basis for new courses on Environmental Nanotechnology. Three new chapters cover the life cycle of nanomaterial fabrication and use and estimating nanomaterial exposure in the environment. A systematic discussion of the effects of nanomaterials on organisms and ecosystems is included, where the previous edition was largely limited to speculation. Features 75% new material New chapter on the life cycle aspects of nanomaterial fabrication and use Two new chapters on estimating nanomaterial exposure in the environment: implications that explore nanotoxicology; exposure estimation Contains end-of-chapter problems and questions

Dissertation Abstracts International

Dissertation Abstracts International Book
Author : Anonim
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Journal of Nanoscience and Nanotechnology

Journal of Nanoscience and Nanotechnology Book
Author : Anonim
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Indian Journal of Engineering and Materials Sciences

Indian Journal of Engineering and Materials Sciences Book
Author : Anonim
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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An Introduction to Green Nanotechnology

An Introduction to Green Nanotechnology Book
Author : Mahmoud Nasrollahzadeh,Mohammad S. Sajadi,Monireh Atarod,Mohaddeseh Sajjadi,Zahra Isaabadi
Publisher : Academic Press
Release : 2019-03-01
ISBN : 0128135875
Language : En, Es, Fr & De

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Book Description :

An Introduction to Green Nanotechnology, Volume 28, provides students, scientists and chemical engineers with an overview of several types of nanostructures, discusses the synthesis and characterization of nanostructures, and provides applications of nanotechnology in daily life. The book offers a foundation to green nanotechnology by explaining why green nanotechnology is important. Covers biological sources in green nanotechnology, antioxidants, green nanostructures, mechanism, synthesis and characterization. The book ends with an evaluation of the risks of nanotechnology in human life and future perspectives. Introduces novel sources of plants having a high potential to be used as bio media to synthesize nanostructures Provides phytochemical properties and antioxidant potential, and their effects on stability, morphology and size of green nanostructures Includes a medicinal and technological comparison of green synthesized nanostructures to nano-products from non-green methods Uses accessible language, avoiding complex concepts of mathematics, biology and chemistry

Reaching the Tumour

Reaching the Tumour Book
Author : Natalia Feiner Gracia
Publisher : Unknown
Release : 2020
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

"The precise delivery of therapeutic agents to their specific site of action is a big challenge in cancer treatment, which would enhance the efficacy and reduce the side effects of drugs. In this framework, nanotechnology can greatly contribute to the development of novel drug delivery systems. Nowadays, a large number of nanoparticles, differing in chemical nature, have been synthesized and evaluated for their therapeutic performances. However, most of the newly developed delivery systems are ineffective in the clinic because they don't reach the specific cancer cells. One of the main reasons of this failure is the lack of knowledge about the interactions between the designed nanosystems and the biological media before getting to the targeted cells, the so-called nanobiointeractions. In particular, undesired interactions with blood proteins and other molecules in vasculature are often responsible for the poor performance of nanocarriers. Further research about the biological interactions occurring in the blood vessels is needed in order to design novel and improved therapeutic nanoparticles. We believe that the understanding of these critical steps together with an in-depth study of the structural composition of nanoparticles will guide a rational design of systems, increasing their applicability and performance in the clinic. To accomplish a comprehensive study, in this thesis, we propose the use of advanced optical microscopy techniques to investigate the chemical and biological identity of nanomaterials and to understand their role with a nanometric precision.One of the first biological barriers nanoparticles encounter when introduced intravenously to the body are proteins which travel through the blood stream. These molecules form the so-called protein corona: a shell of proteins attached to the surface of the nanoparticle. One of the main drawbacks caused by protein corona formation is the hindering of the nanoparticle's surface, reducing the specific interactions of nanosystems with the cancer cells they are targeting. Protein corona formation is mainly studied using ensemble techniques which give only an approximate idea of the molecules interacting with the surface of the nanoparticles. In chapter two, STORM imaging of corona is presented as a new methodology to obtain an in situ characterization of protein corona on individual nanoparticles. This study reveals a high interparticle heterogeneity regarding the number of proteins per nanoparticle, which may be one of the causes of their poor clinical performance.Protein interactions are not only responsible of reducing specific interactions but can dramatically affect the stability of nanosized delivery systems. Therefore, it is important to study their stability in the blood complex environment. Polyplexes are nanocarriers characterized by the electrostatic interactions between the carrier and the nucleic acid. These systems need to be fully complexed during their circulation in the blood vessels in order to protect their cargo from degradation. Up to now, the challenges in characterizing the molecular distribution of the individual components have limited the rational design of nanosystems. In the third chapter, dSTORM imaging is used to visualize the exact molecular composition of polyplexes. dSTORM imaging unveiled the differences in the stoichiometry of individual systems, revealing a heterogeneity inside the same population. Once the system is fully characterized, his complexation can be followed under different blood-like conditions thanks to the molecular resolution of the technique. This new method allows to determine the real molecular stability of the system in contact with serum proteins and provides mechanistic insights into the disassembly process.The stability in complex biological media is a determining factor of the good performance of drug delivery systems, especially in the use of supramolecular structures, due to their dynamic nature. Therefore, it is necessary to understand the behavior of self-assembled nanoparticles in conditions close to the ones they would confront in vivo. Serum proteins can prematurely disassemble the system, as seen in the previous chapter, and lead to non-selective release of the cargo in healthy tissues. Another critical issue of self-assembling systems is the strong dilution they undergo when injected in blood, which may severely affect the supramolecular stability. Hence, it is of crucial importance to investigate the effect of dilution in biologically relevant media. These issues are often overlooked in the literature, most likely due to the difficulties of studying supramolecular assemblies in complex biological media. In chapter four, micelles that change their fluorescent properties upon disassembly are characterized under different blood- like conditions using a combination of fluorescence spectroscopy and microscopy techniques, allowing to predict the system with the best properties.A last critical step nanoparticles face when injected into the blood vessels is the flow, which may also affect the stability of the system. Moreover, their efficiency is directly proportional to the ability of extravasation from the blood vessel across the tight endothelial layer before reaching the cancer cells. In each of these barriers, the stability of supramolecular systems may be compromised. In chapter five a microfluidic chip mimicking the vascular tumor microenvironment is optimized to study the ability and stability of supramolecular structures during extravasation. A monolayer of human umbilical vein endothelial cells are grown in the microfluidic device forming a blood-vessel-like channel. Moreover, the chip contains a second channel of tumorigenic cells to test the stability of the nanocarrier in the extracellular matrix close to cancer cells after extravasation. This device allows to screen the behavior of the different delivery systems and predicts the most stable and promising system thus optimizing and reducing the pre-clinical and clinical testing." -- TDX.

Nanoscience and Nanotechnology

Nanoscience and Nanotechnology Book
Author : Vicki H. Grassian
Publisher : John Wiley & Sons Incorporated
Release : 2008-10-06
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This comprehensive book covers various aspects of nanoscience and nanotechnology and what is known about the potential environmental and health impacts. Divided into three main sections, the book addresses the toxicity of nanomaterials, fate and transport of nanomaterials in the environment, and occupational health aspects of nanotechonology.

Sustainable Agriculture Reviews 48

Sustainable Agriculture Reviews 48 Book
Author : Inamuddin,Mohd Imran Ahamed,Eric Lichtfouse
Publisher : Springer Nature
Release : 2020-12-21
ISBN : 3030547191
Language : En, Es, Fr & De

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Book Description :

This book reviews advanced techniques for the determination of pesticide residues, with focus on extraction, detectors and cleaning protocols. Chapters also discuss pesticide occurrence, toxicity and remediation.

DNA and RNA Nanobiotechnologies in Medicine Diagnosis and Treatment of Diseases

DNA and RNA Nanobiotechnologies in Medicine  Diagnosis and Treatment of Diseases Book
Author : Volker A. Erdmann,Jan Barciszewski
Publisher : Springer Science & Business Media
Release : 2013-06-20
ISBN : 3642368530
Language : En, Es, Fr & De

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Book Description :

This book will provide latest insights in the functional potentials of ribonucleic acids in medine and the use of Spiegelmer and Spiegelzyme systems. It will also deal with a new type of delivery systems for cellular targeting.

Chemical Engineering Progress

Chemical Engineering Progress Book
Author : Anonim
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Chemical Engineering Progress book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

American Doctoral Dissertations

American Doctoral Dissertations Book
Author : Anonim
Publisher : Unknown
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download American Doctoral Dissertations book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Nanotechnology

Nanotechnology Book
Author : Ronald E. Hester,Roy M. Harrison
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Nanotechnology is a much talked about, and rapidly expanding area of science, which is sometimes little understood. It looks set to make a significant impact on human life and, with numerous commercial developments emerging, will become a major industry over the coming years. Nanotechnology can be broadly described as developing or exploiting products at nanometre dimensions (i.e. as having one dimension less than 100 nanometres). Such materials have a larger surface area to volume ratio than conventional materials which provides them with an increased level of reactivity, and consequently, toxicity per unit mass. This book sets the subject into context by first of all describing the current range of products containing nano-materials and then looking at the consequences for the environment and human health relating to the introduction of nanoparticles and nano-tubes. Nanotechnology: Consequences for Human Health and the Environment discusses some of the more controversial issues associated with the field including: nanoparticles in the environment, occupational exposure, toxicological properties, human health issues and safety. This authoritative and comprehensive book will be of interest to both scientists and technologists but also to regulators and government. This title is also available in hardback.

Research Development

Research   Development Book
Author : Anonim
Publisher : Unknown
Release : 2007-05
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

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Directory of Graduate Research

Directory of Graduate Research Book
Author : American Chemical Society. Committee on Professional Training
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.

Research EU

Research EU  Book
Author : Anonim
Publisher : Unknown
Release : 2013
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Research EU book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Info Source

Info Source Book
Author : Canada
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Info Source book written by Canada, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.